Guide to the Human Genome
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Search of human proteins with 74275352

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74275352 translocator protein isoform PBR-S [Homo sapiens]
         (102 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74275352 translocator protein isoform PBR-S [Homo sapiens]         227   2e-60
gi|71274111 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    32   0.082
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 32   0.11 
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i...    31   0.24 
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s...    31   0.24 
gi|153792074 proline rich 12 [Homo sapiens]                            30   0.41 
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]             30   0.53 
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]              30   0.53 
gi|23397672 homeobox D4 [Homo sapiens]                                 30   0.53 
gi|47157315 Janus kinase 3 [Homo sapiens]                              30   0.53 
gi|169168212 PREDICTED: hypothetical protein LOC100129566 [Homo ...    30   0.53 
gi|20162566 chromosome 7 open reading frame 11 [Homo sapiens]          30   0.53 
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    30   0.53 
gi|169208912 PREDICTED: hypothetical protein [Homo sapiens]            29   0.70 
gi|169208667 PREDICTED: hypothetical protein [Homo sapiens]            29   0.70 
gi|169208084 PREDICTED: hypothetical protein [Homo sapiens]            29   0.70 
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]       29   0.70 
gi|187960042 selectin E precursor [Homo sapiens]                       29   0.91 
gi|89886480 zinedin isoform 2 [Homo sapiens]                           29   0.91 
gi|89886477 zinedin isoform 1 [Homo sapiens]                           29   0.91 
gi|142976884 phospholipase A2, group III precursor [Homo sapiens]      29   0.91 
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]            29   0.91 
gi|238859653 pleckstrin homology domain containing family A memb...    28   1.2  
gi|238859651 pleckstrin homology domain containing family A memb...    28   1.2  
gi|169167975 PREDICTED: hypothetical protein LOC100129566 [Homo ...    28   1.2  
gi|113414915 PREDICTED: hypothetical protein [Homo sapiens]            28   1.2  
gi|169167690 PREDICTED: hypothetical protein LOC100129566 [Homo ...    28   1.2  
gi|239741942 PREDICTED: hypothetical protein [Homo sapiens]            28   1.2  
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]            28   1.2  
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]             28   1.2  

>gi|74275352 translocator protein isoform PBR-S [Homo sapiens]
          Length = 102

 Score =  227 bits (578), Expect = 2e-60
 Identities = 102/102 (100%), Positives = 102/102 (100%)

Query: 1   MAPHLLWCPTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDHTQLLR 60
           MAPHLLWCPTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDHTQLLR
Sbjct: 1   MAPHLLWCPTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDHTQLLR 60

Query: 61  MAGQPWLAWGTAAARVSARPTRDCSCTSRCHHACDVVAVTLS 102
           MAGQPWLAWGTAAARVSARPTRDCSCTSRCHHACDVVAVTLS
Sbjct: 61  MAGQPWLAWGTAAARVSARPTRDCSCTSRCHHACDVVAVTLS 102


>gi|71274111 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           A [Homo sapiens]
          Length = 353

 Score = 32.3 bits (72), Expect = 0.082
 Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 2/36 (5%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPAL 44
           P+ G G GG   G  GGGS   G  PG P+G P A+
Sbjct: 71  PSPGTGGGGGAGG--GGGSSQAGGAPGPPSGGPGAV 104


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 20/51 (39%), Positives = 21/51 (41%)

Query: 15  LGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDHTQLLRMAGQP 65
           LG  PA          GL PG P G PP L  PG+ GL      L   G P
Sbjct: 413 LGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPP 463


>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
           isoform [Homo sapiens]
          Length = 302

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 18/43 (41%), Positives = 19/43 (44%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAG 51
           P+ G GLGG   G  GGGS   G    EP   P     PG  G
Sbjct: 98  PSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140


>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
           sapiens]
          Length = 411

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 18/43 (41%), Positives = 19/43 (44%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAG 51
           P+ G GLGG   G  GGGS   G    EP   P     PG  G
Sbjct: 98  PSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 13/88 (14%)

Query: 12  GLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDHT------QLLRMAGQP 65
           G G GG  A        Y G  P  P+G PP    PGLA    ++      QL  + G+P
Sbjct: 458 GQGFGGGQAQDLSKAPSYSGGPPQPPSGPPP----PGLATCQSYSPDQLQGQLYGVQGEP 513

Query: 66  WLAWGTAAARVSARPTRDCSCTSRCHHA 93
           +      AA     PT   S +    H+
Sbjct: 514 YPG---PAAHSQGLPTASPSLSYSTGHS 538


>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
          Length = 392

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 3/40 (7%)

Query: 12  GLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAG 51
           G G+  SP+  W GG    G  P +    PP +P P  AG
Sbjct: 347 GFGVDQSPSAAWMGGF---GAQPPQGQAPPPVIPPPNQAG 383


>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 3/40 (7%)

Query: 12  GLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAG 51
           G G+  SP+  W GG    G  P +    PP +P P  AG
Sbjct: 330 GFGVDQSPSAAWMGGF---GAQPPQGQAPPPVIPPPNQAG 366


>gi|23397672 homeobox D4 [Homo sapiens]
          Length = 255

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 18/49 (36%), Positives = 21/49 (42%), Gaps = 2/49 (4%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDHTQ 57
           P + L   G      G G HY    PGEP   PPA P   L G   ++Q
Sbjct: 69  PGSALPARGHGQEPGGPGGHYAA--PGEPCPAPPAPPPAPLPGARAYSQ 115


>gi|47157315 Janus kinase 3 [Homo sapiens]
          Length = 1124

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 2/36 (5%)

Query: 36  EPAGRPPA--LPLPGLAGLHDHTQLLRMAGQPWLAW 69
           +PAG      + LPG  G HD   LLR+AG   +AW
Sbjct: 246 DPAGAAETFHVGLPGALGGHDGLGLLRVAGDGGIAW 281


>gi|169168212 PREDICTED: hypothetical protein LOC100129566 [Homo
           sapiens]
          Length = 155

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 10/54 (18%)

Query: 2   APHLLWCPTNGLGLGGSPAGQWGGG---------SHYRGLVPGEPAGRPPALPL 46
           APH+   P   + +G  P G   GG           +R ++PG P  RPPA P+
Sbjct: 94  APHMRGPPMMPM-MGPPPPGMMPGGPAPGMRPLMGGHRPMMPGSPVIRPPACPM 146


>gi|20162566 chromosome 7 open reading frame 11 [Homo sapiens]
          Length = 179

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 18/40 (45%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 17 GSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDHT 56
          G   G WG GS +RG  PG    RPP+ P  G    H HT
Sbjct: 15 GPGGGGWGSGSSFRG-TPGGGGPRPPS-PRDGYGSPH-HT 51


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 21/57 (36%), Positives = 21/57 (36%), Gaps = 7/57 (12%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDHTQLLRMAGQP 65
           P  G G GG P G  GGG       PG   G P    L G A  H H   L     P
Sbjct: 153 PGGGGGPGGGPGGGGGGG-------PGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHP 202


>gi|169208912 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 17  GSPAGQWGGGSHYRGLVPGE---PAGRPPALPLPGLAGLHDHTQLLRMAGQPWLAWGTAA 73
           G+P   W  G    G   GE   P G  P     G  G+   +  + ++   +L+W ++ 
Sbjct: 45  GAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLS---FLSWSSSR 101

Query: 74  ARVSARPTRDCSCTSR 89
            RV AR +   +C+ R
Sbjct: 102 CRVPARSSAASACSCR 117


>gi|169208667 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 17  GSPAGQWGGGSHYRGLVPGE---PAGRPPALPLPGLAGLHDHTQLLRMAGQPWLAWGTAA 73
           G+P   W  G    G   GE   P G  P     G  G+   +  + ++   +L+W ++ 
Sbjct: 45  GAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLS---FLSWSSSR 101

Query: 74  ARVSARPTRDCSCTSR 89
            RV AR +   +C+ R
Sbjct: 102 CRVPARSSAASACSCR 117


>gi|169208084 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 266

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 6/76 (7%)

Query: 17  GSPAGQWGGGSHYRGLVPGE---PAGRPPALPLPGLAGLHDHTQLLRMAGQPWLAWGTAA 73
           G+P   W  G    G   GE   P G  P     G  G+   +  + ++   +L+W ++ 
Sbjct: 45  GAPGAPWRRGDEGPGPAGGEAGGPCGAAPGGCASGGCGVMGVSLTVSLS---FLSWSSSR 101

Query: 74  ARVSARPTRDCSCTSR 89
            RV AR +   +C+ R
Sbjct: 102 CRVPARSSAASACSCR 117


>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
          Length = 734

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 2/63 (3%)

Query: 23  WGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDHTQLLRMAGQPWLAWGTAA--ARVSARP 80
           WG  +H  G+    PA   P  P+  L       + +R+  Q WL  G     A + A P
Sbjct: 216 WGSRNHSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACP 275

Query: 81  TRD 83
             D
Sbjct: 276 VSD 278


>gi|187960042 selectin E precursor [Homo sapiens]
          Length = 610

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 28/82 (34%), Positives = 36/82 (43%), Gaps = 6/82 (7%)

Query: 8   CPTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLH-DHTQLLRMAGQPW 66
           CP  G  L GS A   G   H+ GL+P   A  P    +P +AGL      LL +A  P+
Sbjct: 520 CP-EGWTLNGSAARTCGATGHWSGLLPTCEA--PTESNIPLVAGLSAAGLSLLTLA--PF 574

Query: 67  LAWGTAAARVSARPTRDCSCTS 88
           L W     R + +     SC S
Sbjct: 575 LLWLRKCLRKAKKFVPASSCQS 596


>gi|89886480 zinedin isoform 2 [Homo sapiens]
          Length = 760

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 5/47 (10%)

Query: 9  PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDH 55
          P +    G  PAG+ GGG    G  PG  AG P  L LPG+     H
Sbjct: 33 PVSAPAPGPGPAGKGGGG----GGSPGPTAG-PEPLSLPGILHFIQH 74


>gi|89886477 zinedin isoform 1 [Homo sapiens]
          Length = 753

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 5/47 (10%)

Query: 9  PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLPGLAGLHDH 55
          P +    G  PAG+ GGG    G  PG  AG P  L LPG+     H
Sbjct: 33 PVSAPAPGPGPAGKGGGG----GGSPGPTAG-PEPLSLPGILHFIQH 74


>gi|142976884 phospholipase A2, group III precursor [Homo sapiens]
          Length = 509

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 15/29 (51%), Positives = 17/29 (58%), Gaps = 1/29 (3%)

Query: 12 GLGLGGSPAGQWGGGS-HYRGLVPGEPAG 39
          G+ LGGSPA +W   S H    VPG P G
Sbjct: 15 GVALGGSPALRWYRTSCHLTKAVPGNPLG 43


>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
          Length = 284

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 10/47 (21%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPP----ALPLPGLAG 51
           P  G+   G+P G +GG +      PG P G+PP        PGL G
Sbjct: 67  PNPGMFPSGTPGGPYGGAA------PGGPYGQPPPSSYGAQQPGLYG 107


>gi|238859653 pleckstrin homology domain containing family A member
           4 isoform 2 [Homo sapiens]
          Length = 583

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 17/45 (37%), Positives = 20/45 (44%)

Query: 37  PAGRPPALPLPGLAGLHDHTQLLRMAGQPWLAWGTAAARVSARPT 81
           PA RPPA           HT L R+  +P L WG     +S  PT
Sbjct: 252 PARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPT 296


>gi|238859651 pleckstrin homology domain containing family A member
           4 isoform 1 [Homo sapiens]
          Length = 779

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 17/45 (37%), Positives = 20/45 (44%)

Query: 37  PAGRPPALPLPGLAGLHDHTQLLRMAGQPWLAWGTAAARVSARPT 81
           PA RPPA           HT L R+  +P L WG     +S  PT
Sbjct: 252 PARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPT 296


>gi|169167975 PREDICTED: hypothetical protein LOC100129566 [Homo
           sapiens]
          Length = 155

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 14/38 (36%), Positives = 19/38 (50%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPL 46
           P  G+  GG   G       +R ++PG P  RPPA P+
Sbjct: 109 PPPGMMPGGPAPGMRPLMGGHRPMMPGSPVIRPPACPM 146


>gi|113414915 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 220

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 3/46 (6%)

Query: 8  CPTNGLGLGGSPAGQWGGGSH---YRGLVPGEPAGRPPALPLPGLA 50
          CP      GG PAG   GG+      G + G      PA P PGL+
Sbjct: 38 CPNPASATGGGPAGSRDGGAQGPVSSGRIQGGSRRPLPAGPHPGLS 83


>gi|169167690 PREDICTED: hypothetical protein LOC100129566 [Homo
           sapiens]
          Length = 155

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 14/38 (36%), Positives = 19/38 (50%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPL 46
           P  G+  GG   G       +R ++PG P  RPPA P+
Sbjct: 109 PPPGMMPGGPAPGMRPLMGGHRPMMPGSPVIRPPACPM 146


>gi|239741942 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 220

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 3/46 (6%)

Query: 8  CPTNGLGLGGSPAGQWGGGSH---YRGLVPGEPAGRPPALPLPGLA 50
          CP      GG PAG   GG+      G + G      PA P PGL+
Sbjct: 38 CPNPASATGGGPAGSRDGGAQGPVSSGRIQGGSRRPLPAGPHPGLS 83


>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
          Length = 397

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/39 (38%), Positives = 17/39 (43%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLP 47
           P+  LG      G   G   YR L PG P G PP+   P
Sbjct: 286 PSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAP 324


>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
          Length = 402

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/39 (38%), Positives = 17/39 (43%)

Query: 9   PTNGLGLGGSPAGQWGGGSHYRGLVPGEPAGRPPALPLP 47
           P+  LG      G   G   YR L PG P G PP+   P
Sbjct: 291 PSGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAP 329


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.492 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,257,125
Number of Sequences: 37866
Number of extensions: 300080
Number of successful extensions: 1543
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 81
Number of HSP's that attempted gapping in prelim test: 1438
Number of HSP's gapped (non-prelim): 185
length of query: 102
length of database: 18,247,518
effective HSP length: 73
effective length of query: 29
effective length of database: 15,483,300
effective search space: 449015700
effective search space used: 449015700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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