Guide to the Human Genome
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Name: JAK3 Sequence: fasta or formatted (1124aa) NCBI GI: 47157315
Description:

Janus kinase 3

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.8         88           2
 C cysteine            2.8         32           2
 D aspartate           5.2         59           1
 E glutamate           5.9         66           2
 F phenylalanine       4.1         46           2
 G glycine             7.0         79           2
 H histidine           3.3         37           2
 I isoleucine          3.3         37           1
 K lysine              3.7         42           2
 L leucine            13.4        151           3
 M methionine          1.8         20           2
 N asparagine          1.3         15           1
 P proline             6.9         77           2
 Q glutamine           4.7         53           2
 R arginine            6.9         78           3
 S serine              7.9         89           2
 T threonine           3.4         38           2
 V valine              6.4         72           2
 W tryptophan          1.3         15           1
 Y tyrosine            2.7         30           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Janus kinase 3 
JAK2                  0.460   Janus kinase 2 
JAK1                  0.327   janus kinase 1 
TYK2                  0.304   tyrosine kinase 2 
ERBB4                 0.070   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.070   v-erb-a erythroblastic leukemia viral oncogene homolo...
EGFR                  0.069   epidermal growth factor receptor isoform a precursor...
TNK2                  0.069   tyrosine kinase, non-receptor, 2 isoform 1 
TNK2                  0.069   tyrosine kinase, non-receptor, 2 isoform 2 
ERBB2                 0.068   erbB-2 isoform b 
ERBB2                 0.068   erbB-2 isoform a 
ZAP70                 0.061   zeta-chain associated protein kinase 70kDa isoform 2...
ZAP70                 0.061   zeta-chain associated protein kinase 70kDa isoform 1...
SYK                   0.060   spleen tyrosine kinase isoform 2 
SYK                   0.060   spleen tyrosine kinase isoform 1 
FGFR4                 0.060   fibroblast growth factor receptor 4 isoform 2 precur...
FGFR4                 0.060   fibroblast growth factor receptor 4 isoform 1 precur...
FGFR4                 0.060   fibroblast growth factor receptor 4 isoform 1 precur...
NTRK1                 0.059   neurotrophic tyrosine kinase, receptor, type 1 isofo...
NTRK1                 0.059   neurotrophic tyrosine kinase, receptor, type 1 isofor...
NTRK1                 0.059   neurotrophic tyrosine kinase, receptor, type 1 isofo...
SRMS                  0.059   src-related kinase lacking C-terminal regulatory tyr...
TEK                   0.058   TEK tyrosine kinase, endothelial precursor 
ABL2                  0.057   arg tyrosine kinase isoform c 
ABL2                  0.057   arg tyrosine kinase isoform b 
ABL2                  0.057   arg tyrosine kinase isoform e 
ABL2                  0.057   arg tyrosine kinase isoform d 
ABL2                  0.057   arg tyrosine kinase isoform a 
PTK7                  0.057   PTK7 protein tyrosine kinase 7 isoform a precursor [...
PTK7                  0.057   PTK7 protein tyrosine kinase 7 isoform d precursor [...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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