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Search of human proteins with 74229019
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo
sapiens]
(719 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo sa... 1482 0.0
gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo sa... 1408 0.0
gi|45007007 2'-5'oligoadenylate synthetase 3 [Homo sapiens] 574 e-164
gi|74229015 2',5'-oligoadenylate synthetase 1 isoform 3 [Homo sa... 378 e-105
gi|74229013 2',5'-oligoadenylate synthetase 1 isoform 1 [Homo sa... 368 e-102
gi|74229011 2',5'-oligoadenylate synthetase 1 isoform 2 [Homo sa... 368 e-102
gi|74229021 2'-5'-oligoadenylate synthetase 2 isoform 3 [Homo sa... 304 2e-82
gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo... 228 1e-59
gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo... 123 5e-28
gi|7656888 angiopoietin-like 3 precursor [Homo sapiens] 33 0.92
gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens] 33 0.92
gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens] 33 0.92
gi|156142186 cytokine receptor-like factor 3 [Homo sapiens] 33 1.2
gi|111548654 hypothetical protein LOC51057 isoform 1 [Homo sapiens] 32 2.1
gi|111548652 hypothetical protein LOC51057 isoform 2 [Homo sapiens] 32 2.1
gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens] 32 2.7
gi|18254456 testis-specific gene A2 [Homo sapiens] 31 3.5
gi|13376259 nucleoporin 85 [Homo sapiens] 31 3.5
gi|28872780 cytosine-5-methyltransferase 3-like protein isoform ... 30 6.0
gi|28872778 cytosine-5-methyltransferase 3-like protein isoform ... 30 6.0
gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens] 30 6.0
gi|33186882 testis serine protease 2 [Homo sapiens] 30 6.0
gi|33946311 solute carrier family 8 (sodium/calcium exchanger), ... 30 6.0
gi|188528616 testis specific, 10 [Homo sapiens] 30 7.8
gi|13376858 testis specific, 10 [Homo sapiens] 30 7.8
gi|239751222 PREDICTED: hypothetical protein XP_002347759 [Homo ... 30 7.8
gi|239745712 PREDICTED: hypothetical protein XP_002343531 [Homo ... 30 7.8
>gi|74229019 2'-5'-oligoadenylate synthetase 2 isoform 1 [Homo
sapiens]
Length = 719
Score = 1482 bits (3837), Expect = 0.0
Identities = 719/719 (100%), Positives = 719/719 (100%)
Query: 1 MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60
MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG
Sbjct: 1 MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60
Query: 61 GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120
GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI
Sbjct: 61 GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120
Query: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC 180
QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC
Sbjct: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC 180
Query: 181 FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD 240
FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD
Sbjct: 181 FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD 240
Query: 241 NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN 300
NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN
Sbjct: 241 NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN 300
Query: 301 VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK 360
VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK
Sbjct: 301 VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK 360
Query: 361 CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS 420
CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS
Sbjct: 361 CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS 420
Query: 421 YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF 480
YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF
Sbjct: 421 YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF 480
Query: 481 DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK 540
DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK
Sbjct: 481 DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK 540
Query: 541 DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT 600
DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT
Sbjct: 541 DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT 600
Query: 601 QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA 660
QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA
Sbjct: 601 QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA 660
Query: 661 KEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIHPIVNEMFSSRSHRILNNNSKRNF 719
KEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIHPIVNEMFSSRSHRILNNNSKRNF
Sbjct: 661 KEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIHPIVNEMFSSRSHRILNNNSKRNF 719
>gi|74229017 2'-5'-oligoadenylate synthetase 2 isoform 2 [Homo
sapiens]
Length = 687
Score = 1408 bits (3645), Expect = 0.0
Identities = 683/683 (100%), Positives = 683/683 (100%)
Query: 1 MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60
MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG
Sbjct: 1 MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60
Query: 61 GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120
GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI
Sbjct: 61 GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120
Query: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC 180
QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC
Sbjct: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVC 180
Query: 181 FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD 240
FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD
Sbjct: 181 FTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKD 240
Query: 241 NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN 300
NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN
Sbjct: 241 NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNN 300
Query: 301 VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK 360
VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK
Sbjct: 301 VSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNK 360
Query: 361 CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS 420
CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS
Sbjct: 361 CFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKS 420
Query: 421 YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF 480
YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF
Sbjct: 421 YTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSF 480
Query: 481 DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK 540
DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK
Sbjct: 481 DVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLK 540
Query: 541 DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT 600
DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT
Sbjct: 541 DLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVT 600
Query: 601 QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA 660
QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA
Sbjct: 601 QYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEA 660
Query: 661 KEWLSSPCFKDGTGNPIPPWKVP 683
KEWLSSPCFKDGTGNPIPPWKVP
Sbjct: 661 KEWLSSPCFKDGTGNPIPPWKVP 683
>gi|45007007 2'-5'oligoadenylate synthetase 3 [Homo sapiens]
Length = 1087
Score = 574 bits (1480), Expect = e-164
Identities = 336/699 (48%), Positives = 445/699 (63%), Gaps = 47/699 (6%)
Query: 8 LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKT 67
LS +P ++L FIQ++LKP + Q + + ++ I L E V+ GGS+GR T
Sbjct: 408 LSQIPTKELDRFIQDHLKPSPQFQEQVKKAIDIILRCLHE-NCVHKASRVSKGGSFGRGT 466
Query: 68 VLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKW-------LKNNFEI 120
LR D L++F + ++DQ + +ILD+ +L+ W L F
Sbjct: 467 DLRDGCDVELIIFLNCFTDYKDQGPRRAEILDEMRAQLE-----SWWQDQVPSLSLQFPE 521
Query: 121 QKSLDGFTIQVFTKNQRISFEV--LAAFNA---LSLNDNPSPWIYRELKRSLDKTNASPG 175
Q + Q+ + + +V L AF+A LS P+P +Y L S G
Sbjct: 522 QNVPEALQFQLVSTALKSWTDVSLLPAFDAVGQLSSGTKPNPQVYSRLLTS----GCQEG 577
Query: 176 EFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDL----PSLSP-YALELLTV 230
E CF EL++ F + RP KLK+LILL+KHW++Q + K SL P YALELLT+
Sbjct: 578 EHKACFAELRRNFMNIRPVKLKNLILLVKHWYRQVAAQNKGKGPAPASLPPAYALELLTI 637
Query: 231 YAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPV 290
+AWEQGCR+D F++A+G RTVL L++ ++LC+YW VNY+ ED +R LL QL+ RP+
Sbjct: 638 FAWEQGCRQDCFNMAQGFRTVLGLVQQHQQLCVYWTVNYSTEDPAMRMHLLGQLRKPRPL 697
Query: 291 ILDPVDPTNNVSGDKICWQWLKKEA-----QTWLTSPNLDNELPAPSWNVLPAPLFTTPG 345
+LDP DPT NV W+ L +EA Q S + + P W+V+PA L+ TP
Sbjct: 698 VLDPADPTWNVGHGS--WELLAQEAAALGMQACFLSRDGTSVQP---WDVMPALLYQTPA 752
Query: 346 HLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAK-IQIVRGGSTAKGTALK 404
LDKFI EFLQPN+ FL Q++ AV+ I +FLKENCFR S K I++V+GGS+AKGTAL+
Sbjct: 753 GDLDKFISEFLQPNRQFLAQVNKAVDTICSFLKENCFRNSPIKVIKVVKGGSSAKGTALR 812
Query: 405 TGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRV 464
SDADLVVF + +T Q N+R +I+ EI QL+A ++E + EV FE KW+ PRV
Sbjct: 813 GRSDADLVVFLSCFSQFTEQGNKRAEIISEIRAQLEAC--QQERQFEVKFEVSKWENPRV 870
Query: 465 LSFSLKSK-VLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTC 523
LSFSL S+ +L++SV FDVLPAF+ALGQL SGS PS +VY LI Y ++ GE+STC
Sbjct: 871 LSFSLTSQTMLDQSVDFDVLPAFDALGQLVSGSRPSSQVYVDLIHSYSNA----GEYSTC 926
Query: 524 FTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGV 583
FT LQR+FI SRPTKLK LIRLVKHWY++C + K +GSLPP++ LELLT+YAWEQG
Sbjct: 927 FTELQRDFIISRPTKLKSLIRLVKHWYQQCTKISKGRGSLPPQHGLELLTVYAWEQGGKD 986
Query: 584 PDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTG 643
F+ AEGFRTVLELVTQY+QLCI+W +NYN +D+TV FL QLQK RP+ILDPA+PTG
Sbjct: 987 SQFNMAEGFRTVLELVTQYRQLCIYWTINYNAKDKTVGDFLKQQLQKPRPIILDPADPTG 1046
Query: 644 DVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKV 682
++G R W LLAKEA S+ C G PI PW V
Sbjct: 1047 NLGHNAR--WDLLAKEAAACTSALCCMGRNGIPIQPWPV 1083
Score = 446 bits (1146), Expect = e-125
Identities = 291/773 (37%), Positives = 403/773 (52%), Gaps = 116/773 (15%)
Query: 8 LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP-----EQFPLVQGVAIGGS 62
L S PA L F+ L+P +E + + L+E P V GGS
Sbjct: 3 LYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRERGGRLGAAAPRVLKTVKGGS 62
Query: 63 YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFE--- 119
GR T L+G D LV+F K + DQ+ + +IL + L+ W +N
Sbjct: 63 SGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLE-----SWWQNPVPGLR 117
Query: 120 ---IQKSLDG---FTIQVFTKNQRISFEVLAAFNALSLNDN---PSPWIYRELKRSLDKT 170
++S+ G F + + ++ AFN L + P P +Y L S
Sbjct: 118 LTFPEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLNS---- 173
Query: 171 NASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHW-HQQCQKKI--KDLPSLSPYALEL 227
GE A CFTEL++ F + RP KLK+LILL+KHW HQ C + + + LP + YALEL
Sbjct: 174 GCQGGEHAACFTELRRNFVNIRPAKLKNLILLVKHWYHQVCLQGLWKETLPPV--YALEL 231
Query: 228 LTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSA 287
LT++AWEQGC+KD F +AEG+RTVL LI+ + LC++W VNY FED + L QL+
Sbjct: 232 LTIFAWEQGCKKDAFSLAEGLRTVLGLIQQHQHLCVFWTVNYGFEDPAVGQFLQRQLKRP 291
Query: 288 RPVILDPVDPTNNVSGDKICWQW--LKKEA-----------------QTWL--------- 319
RPVILDP DPT ++ G+ W W L +EA Q+W
Sbjct: 292 RPVILDPADPTWDL-GNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSWKGPGLPRAGC 350
Query: 320 --------TSPNLDNELPAPSWNVL-----------PAP------------------LFT 342
PN + S N + PAP L
Sbjct: 351 SGLGHPIQLDPNQKTPENSKSLNAVYPRAGSKPPSCPAPGPTGAASIVPSVPGMALDLSQ 410
Query: 343 TPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTA 402
P LD+FI++ L+P+ F EQ+ A++II L ENC +++ ++ +GGS +GT
Sbjct: 411 IPTKELDRFIQDHLKPSPQFQEQVKKAIDIILRCLHENCVHKAS---RVSKGGSFGRGTD 467
Query: 403 LKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAP 462
L+ G D +L++F N Y Q R +I+ E+ QL+++W+++ L + F P+ P
Sbjct: 468 LRDGCDVELIIFLNCFTDYKDQGPRRAEILDEMRAQLESWWQDQVPSLSLQF--PEQNVP 525
Query: 463 RVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFST 522
L F L S L +LPAF+A+GQLSSG+ P+P+VY+ L+ +S GE
Sbjct: 526 EALQFQLVSTALKSWTDVSLLPAFDAVGQLSSGTKPNPQVYSRLL----TSGCQEGEHKA 581
Query: 523 CFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKG----SLPPKYALELLTIYAWE 578
CF L+RNF+ RP KLK+LI LVKHWY++ + K KG SLPP YALELLTI+AWE
Sbjct: 582 CFAELRRNFMNIRPVKLKNLILLVKHWYRQVAAQNKGKGPAPASLPPAYALELLTIFAWE 641
Query: 579 QGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDP 638
QG F+ A+GFRTVL LV Q+QQLC++W VNY+ ED +R LL QL+K RP++LDP
Sbjct: 642 QGCRQDCFNMAQGFRTVLGLVQQHQQLCVYWTVNYSTEDPAMRMHLLGQLRKPRPLVLDP 701
Query: 639 AEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKV-PTM--QTP 688
A+PT +VG G W LLA+EA CF G + PW V P + QTP
Sbjct: 702 ADPTWNVGHGS---WELLAQEAAALGMQACFLSRDGTSVQPWDVMPALLYQTP 751
Score = 307 bits (787), Expect = 2e-83
Identities = 164/362 (45%), Positives = 221/362 (61%), Gaps = 10/362 (2%)
Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAK---IQIVRGGS 396
L++TP LD+F+ LQP K F+E+ A+ + L+E R A ++ V+GGS
Sbjct: 3 LYSTPAAALDRFVARRLQPRKEFVEKARRALGALAAALRERGGRLGAAAPRVLKTVKGGS 62
Query: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456
+ +GTALK G D++LV+F + KSY Q+ R +I+ E+ L+++W+ L ++F
Sbjct: 63 SGRGTALKGGCDSELVIFLDCFKSYVDQRARRAEILSEMRASLESWWQNPVPGLRLTF-- 120
Query: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516
P+ P L F L S L + + ++PAFN LGQ SG P P+VY+ L++ S
Sbjct: 121 PEQSVPGALQFRLTSVDLEDWMDVSLVPAFNVLGQAGSGVKPKPQVYSTLLN----SGCQ 176
Query: 517 GGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYA 576
GGE + CFT L+RNF+ RP KLK+LI LVKHWY + + K +LPP YALELLTI+A
Sbjct: 177 GGEHAACFTELRRNFVNIRPAKLKNLILLVKHWYHQVCLQGLWKETLPPVYALELLTIFA 236
Query: 577 WEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVIL 636
WEQG F AEG RTVL L+ Q+Q LC+FW VNY FED V +FL QL++ RPVIL
Sbjct: 237 WEQGCKKDAFSLAEGLRTVLGLIQQHQHLCVFWTVNYGFEDPAVGQFLQRQLKRPRPVIL 296
Query: 637 DPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIH 696
DPA+PT D+G G W W LLA+EA PCF G G+P+ WK P + G C H
Sbjct: 297 DPADPTWDLGNGAAWHWDLLAQEAASCYDHPCFLRGMGDPVQSWKGPGLPRAG-CSGLGH 355
Query: 697 PI 698
PI
Sbjct: 356 PI 357
>gi|74229015 2',5'-oligoadenylate synthetase 1 isoform 3 [Homo
sapiens]
Length = 414
Score = 378 bits (971), Expect = e-105
Identities = 194/362 (53%), Positives = 255/362 (70%), Gaps = 13/362 (3%)
Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKI---QIVRGGS 396
L TP LDKFI+++L P+ CF QI+ A++II FLKE CFR S+ + ++V+GGS
Sbjct: 4 LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
Query: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456
+ KGT L+ SDADLVVF + L ++ Q N R + ++EI QL+A RE+ ++ +
Sbjct: 64 SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
Query: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516
P+W PR LSF L S L E V FDVLPAF+ALGQL+ G P+P++Y LI+ + +DL
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIE--ECTDLQ 181
Query: 517 G-GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIY 575
GEFSTCFT LQR+F++ RPTKLK LIRLVKHWY+ C++KL G LPP+YALELLT+Y
Sbjct: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKL---GKLPPQYALELLTVY 238
Query: 576 AWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVI 635
AWE+GS F+TA+GFRTVLELV YQQLCI+W Y+F++ + K+L QL K RPVI
Sbjct: 239 AWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVI 298
Query: 636 LDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARI 695
LDPA+PTG++GGGD W LA+EA+ WL+ PCFK+ G+P+ W + T TPGS I
Sbjct: 299 LDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQHTPGS----I 354
Query: 696 HP 697
HP
Sbjct: 355 HP 356
Score = 230 bits (586), Expect = 4e-60
Identities = 144/357 (40%), Positives = 194/357 (54%), Gaps = 23/357 (6%)
Query: 8 LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP----EQFPL-VQGVAIGGS 62
L + PA+ L FI++YL P + I+ ++ IC L+E +P+ V V GGS
Sbjct: 4 LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
Query: 63 YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQK 122
G+ T LRG SD LV+F S L FQDQ + + + + +L+ C + FE+Q
Sbjct: 64 SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
Query: 123 SLDG------FTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLDKTNAS 173
G F + + + F+VL AF+AL P+P IY +L
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKE 183
Query: 174 PGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAW 233
GEF+ CFTELQ+ F RP KLK LI L+KHW+Q C+KK+ LP YALELLTVYAW
Sbjct: 184 -GEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPP--QYALELLTVYAW 240
Query: 234 EQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILD 293
E+G K +F+ A+G RTVLEL+ ++LCIYW Y+F++ I L QL RPVILD
Sbjct: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300
Query: 294 PVDPTNNV-SGDKICWQWLKKEAQTWLTSPNLDN--ELPAPSWNVLPAPLFTTPGHL 347
P DPT N+ GD W+ L +EA+ WL P N P SW +L TPG +
Sbjct: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLTQ---HTPGSI 354
>gi|74229013 2',5'-oligoadenylate synthetase 1 isoform 1 [Homo
sapiens]
Length = 400
Score = 368 bits (945), Expect = e-102
Identities = 186/345 (53%), Positives = 246/345 (71%), Gaps = 9/345 (2%)
Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKI---QIVRGGS 396
L TP LDKFI+++L P+ CF QI+ A++II FLKE CFR S+ + ++V+GGS
Sbjct: 4 LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
Query: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456
+ KGT L+ SDADLVVF + L ++ Q N R + ++EI QL+A RE+ ++ +
Sbjct: 64 SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
Query: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516
P+W PR LSF L S L E V FDVLPAF+ALGQL+ G P+P++Y LI+ + +DL
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIE--ECTDLQ 181
Query: 517 G-GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIY 575
GEFSTCFT LQR+F++ RPTKLK LIRLVKHWY+ C++KL G LPP+YALELLT+Y
Sbjct: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKL---GKLPPQYALELLTVY 238
Query: 576 AWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVI 635
AWE+GS F+TA+GFRTVLELV YQQLCI+W Y+F++ + K+L QL K RPVI
Sbjct: 239 AWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVI 298
Query: 636 LDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPW 680
LDPA+PTG++GGGD W LA+EA+ WL+ PCFK+ G+P+ W
Sbjct: 299 LDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343
Score = 229 bits (585), Expect = 5e-60
Identities = 141/346 (40%), Positives = 190/346 (54%), Gaps = 20/346 (5%)
Query: 8 LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP----EQFPL-VQGVAIGGS 62
L + PA+ L FI++YL P + I+ ++ IC L+E +P+ V V GGS
Sbjct: 4 LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
Query: 63 YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQK 122
G+ T LRG SD LV+F S L FQDQ + + + + +L+ C + FE+Q
Sbjct: 64 SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
Query: 123 SLDG------FTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLDKTNAS 173
G F + + + F+VL AF+AL P+P IY +L
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKE 183
Query: 174 PGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAW 233
GEF+ CFTELQ+ F RP KLK LI L+KHW+Q C+KK+ LP YALELLTVYAW
Sbjct: 184 -GEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPP--QYALELLTVYAW 240
Query: 234 EQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILD 293
E+G K +F+ A+G RTVLEL+ ++LCIYW Y+F++ I L QL RPVILD
Sbjct: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300
Query: 294 PVDPTNNV-SGDKICWQWLKKEAQTWLTSPNLDN--ELPAPSWNVL 336
P DPT N+ GD W+ L +EA+ WL P N P SW +L
Sbjct: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILL 346
>gi|74229011 2',5'-oligoadenylate synthetase 1 isoform 2 [Homo
sapiens]
Length = 364
Score = 368 bits (945), Expect = e-102
Identities = 186/345 (53%), Positives = 246/345 (71%), Gaps = 9/345 (2%)
Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKI---QIVRGGS 396
L TP LDKFI+++L P+ CF QI+ A++II FLKE CFR S+ + ++V+GGS
Sbjct: 4 LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
Query: 397 TAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEP 456
+ KGT L+ SDADLVVF + L ++ Q N R + ++EI QL+A RE+ ++ +
Sbjct: 64 SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
Query: 457 PKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLP 516
P+W PR LSF L S L E V FDVLPAF+ALGQL+ G P+P++Y LI+ + +DL
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIE--ECTDLQ 181
Query: 517 G-GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIY 575
GEFSTCFT LQR+F++ RPTKLK LIRLVKHWY+ C++KL G LPP+YALELLT+Y
Sbjct: 182 KEGEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKL---GKLPPQYALELLTVY 238
Query: 576 AWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVI 635
AWE+GS F+TA+GFRTVLELV YQQLCI+W Y+F++ + K+L QL K RPVI
Sbjct: 239 AWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVI 298
Query: 636 LDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPW 680
LDPA+PTG++GGGD W LA+EA+ WL+ PCFK+ G+P+ W
Sbjct: 299 LDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSW 343
Score = 231 bits (589), Expect = 2e-60
Identities = 142/349 (40%), Positives = 191/349 (54%), Gaps = 20/349 (5%)
Query: 8 LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP----EQFPL-VQGVAIGGS 62
L + PA+ L FI++YL P + I+ ++ IC L+E +P+ V V GGS
Sbjct: 4 LRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGS 63
Query: 63 YGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQK 122
G+ T LRG SD LV+F S L FQDQ + + + + +L+ C + FE+Q
Sbjct: 64 SGKGTTLRGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQA 123
Query: 123 SLDG------FTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLDKTNAS 173
G F + + + F+VL AF+AL P+P IY +L
Sbjct: 124 PRWGNPRALSFVLSSLQLGEGVEFDVLPAFDALGQLTGGYKPNPQIYVKLIEECTDLQKE 183
Query: 174 PGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAW 233
GEF+ CFTELQ+ F RP KLK LI L+KHW+Q C+KK+ LP YALELLTVYAW
Sbjct: 184 -GEFSTCFTELQRDFLKQRPTKLKSLIRLVKHWYQNCKKKLGKLPP--QYALELLTVYAW 240
Query: 234 EQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILD 293
E+G K +F+ A+G RTVLEL+ ++LCIYW Y+F++ I L QL RPVILD
Sbjct: 241 ERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKNPIIEKYLRRQLTKPRPVILD 300
Query: 294 PVDPTNNV-SGDKICWQWLKKEAQTWLTSPNLDN--ELPAPSWNVLPAP 339
P DPT N+ GD W+ L +EA+ WL P N P SW +L P
Sbjct: 301 PADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLVRP 349
>gi|74229021 2'-5'-oligoadenylate synthetase 2 isoform 3 [Homo
sapiens]
Length = 172
Score = 304 bits (778), Expect = 2e-82
Identities = 150/150 (100%), Positives = 150/150 (100%)
Query: 1 MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60
MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG
Sbjct: 1 MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIG 60
Query: 61 GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120
GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI
Sbjct: 61 GSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEI 120
Query: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALS 150
QKSLDGFTIQVFTKNQRISFEVLAAFNALS
Sbjct: 121 QKSLDGFTIQVFTKNQRISFEVLAAFNALS 150
Score = 63.5 bits (153), Expect = 6e-10
Identities = 47/156 (30%), Positives = 75/156 (48%), Gaps = 16/156 (10%)
Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAK 399
L + P L FI+E+L+P + ID VN I L+E Q + GGS +
Sbjct: 8 LSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP--EQFPLVQGVAIGGSYGR 65
Query: 400 GTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLK----AFWREKEEELEVSFE 455
T L+ SD LV+F + LK + QK + I+ + ++LK W + E++ S +
Sbjct: 66 KTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLD 125
Query: 456 PPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQ 491
F+++ N+ +SF+VL AFNAL +
Sbjct: 126 ----------GFTIQVFTKNQRISFEVLAAFNALSK 151
>gi|11321577 2'-5'-oligoadenylate synthetase-like isoform a [Homo
sapiens]
Length = 514
Score = 228 bits (582), Expect = 1e-59
Identities = 127/352 (36%), Positives = 201/352 (57%), Gaps = 19/352 (5%)
Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFR------QSTAKIQIVR 393
L++TP LD F+ ++LQP++ + E++ AV + FL++ F+ Q +++V+
Sbjct: 7 LYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVK 66
Query: 394 GGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVS 453
GS GT L++ + +LV F + S+ +++ I K W + ++ L++
Sbjct: 67 VGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIW---KTMW-QSQDLLDLG 122
Query: 454 FEPPKW--KAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYK 511
E + + P L F+++++ E ++ ++PA+ ALG S P PEVY LI K
Sbjct: 123 LEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLI---K 179
Query: 512 SSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALEL 571
+ PG F F+ LQRNF++ RPTKLK L+RLVKHWY++ + P+ +LPP YALEL
Sbjct: 180 ACGGPGN-FCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238
Query: 572 LTIYAWEQGSGVPD-FDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQK 630
LTIYAWE G+ + F EGF TV++L+ +Y+ +CI+W Y + + + QL+K
Sbjct: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
Query: 631 TRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKV 682
RP+ILDPA+PT +V G R W ++A+ A + L C D NPI W V
Sbjct: 299 ERPIILDPADPTLNVAEGYR--WDIVAQRASQCLKQDCCYDNRENPISSWNV 348
Score = 169 bits (429), Expect = 6e-42
Identities = 122/351 (34%), Positives = 179/351 (50%), Gaps = 30/351 (8%)
Query: 7 QLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP--------EQFPLVQGVA 58
+L S PA +L F+ ++L+P+ E + + + V T+ + L++ +Q V V
Sbjct: 6 ELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVV 65
Query: 59 IGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILD-------KTGDKLKFCLFT 111
GS+G TVLR + LV F S FQ+ + +D+L ++ D L L
Sbjct: 66 KVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGL-- 123
Query: 112 KWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLD 168
+ L+ + +L FTIQ + I+ ++ A+ AL N P P +Y SL
Sbjct: 124 EDLRMEQRVPDALV-FTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYV----SLI 178
Query: 169 KTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSP-YALEL 227
K PG F F+ELQ+ F +RP KLK L+ L+KHW+QQ K +L P YALEL
Sbjct: 179 KACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALEL 238
Query: 228 LTVYAWEQGCRKD-NFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQS 286
LT+YAWE G +D NF + EG TV++L+ E +CIYW Y + I + + QL+
Sbjct: 239 LTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKK 298
Query: 287 ARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNL--DNELPAPSWNV 335
RP+ILDP DPT NV+ + W + + A L + E P SWNV
Sbjct: 299 ERPIILDPADPTLNVA-EGYRWDIVAQRASQCLKQDCCYDNRENPISSWNV 348
>gi|38016930 2'-5'-oligoadenylate synthetase-like isoform b [Homo
sapiens]
Length = 255
Score = 123 bits (309), Expect = 5e-28
Identities = 72/221 (32%), Positives = 123/221 (55%), Gaps = 16/221 (7%)
Query: 340 LFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFR------QSTAKIQIVR 393
L++TP LD F+ ++LQP++ + E++ AV + FL++ F+ Q +++V+
Sbjct: 7 LYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVK 66
Query: 394 GGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVS 453
GS GT L++ + +LV F + S+ +++ I K W + ++ L++
Sbjct: 67 VGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIW---KTMW-QSQDLLDLG 122
Query: 454 FEPPKW--KAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYK 511
E + + P L F+++++ E ++ ++PA+ ALG S P PEVY LI K
Sbjct: 123 LEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLI---K 179
Query: 512 SSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKE 552
+ PG F F+ LQRNF++ RPTKLK L+RLVKHWY++
Sbjct: 180 ACGGPGN-FCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQ 219
Score = 90.1 bits (222), Expect = 6e-18
Identities = 70/221 (31%), Positives = 109/221 (49%), Gaps = 25/221 (11%)
Query: 7 QLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEP--------EQFPLVQGVA 58
+L S PA +L F+ ++L+P+ E + + + V T+ + L++ +Q V V
Sbjct: 6 ELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVV 65
Query: 59 IGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILD-------KTGDKLKFCLFT 111
GS+G TVLR + LV F S FQ+ + +D+L ++ D L L
Sbjct: 66 KVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGL-- 123
Query: 112 KWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSL---NDNPSPWIYRELKRSLD 168
+ L+ + +L FTIQ + I+ ++ A+ AL N P P +Y SL
Sbjct: 124 EDLRMEQRVPDALV-FTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYV----SLI 178
Query: 169 KTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQ 209
K PG F F+ELQ+ F +RP KLK L+ L+KHW+QQ
Sbjct: 179 KACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQ 219
>gi|7656888 angiopoietin-like 3 precursor [Homo sapiens]
Length = 460
Score = 33.1 bits (74), Expect = 0.92
Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 8/88 (9%)
Query: 401 TALKT---GSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPP 457
T+LKT D + +++ Q N++H +KEI QL+ ++ E+ +S +P
Sbjct: 162 TSLKTFVEKQDNSIKDLLQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKP- 220
Query: 458 KWKAPRVLSFSLKSKVLNESVSFDVLPA 485
+APR F +++ N V D +PA
Sbjct: 221 --RAPRTTPFLQLNEIRN--VKHDGIPA 244
>gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]
Length = 770
Score = 33.1 bits (74), Expect = 0.92
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 9/100 (9%)
Query: 478 VSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRN-----FI 532
VS + + LG + S + ++ +Y S LP + FT L FI
Sbjct: 203 VSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFI 262
Query: 533 RSRPTKLKDLIRLVKHWYK-ECERKLKPKGSLPPKYALEL 571
SRP KD+++L++H Y +C LK L P + L++
Sbjct: 263 NSRPVHQKDILKLIRHHYNLKC---LKESTRLYPVFFLKI 299
>gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]
Length = 932
Score = 33.1 bits (74), Expect = 0.92
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 9/100 (9%)
Query: 478 VSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRN-----FI 532
VS + + LG + S + ++ +Y S LP + FT L FI
Sbjct: 203 VSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFI 262
Query: 533 RSRPTKLKDLIRLVKHWYK-ECERKLKPKGSLPPKYALEL 571
SRP KD+++L++H Y +C LK L P + L++
Sbjct: 263 NSRPVHQKDILKLIRHHYNLKC---LKESTRLYPVFFLKI 299
>gi|156142186 cytokine receptor-like factor 3 [Homo sapiens]
Length = 442
Score = 32.7 bits (73), Expect = 1.2
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 14 QKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPE 49
Q++ QE +KP ++CQ LI+ VNT D+++E E
Sbjct: 79 QEVDTIEQETIKPLDDCQKLIEHGVNTAEDLVREGE 114
>gi|111548654 hypothetical protein LOC51057 isoform 1 [Homo sapiens]
Length = 587
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 7/74 (9%)
Query: 372 IIRTFLKEN--CFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERH 429
II +FL +N CF Q T K++ S+ L+ S D +F+ + ++ ERH
Sbjct: 15 IILSFLAQNKLCFIQFTKKME-----SSDVNKRLEKLSALDYKIFYYEIPGPINKTTERH 69
Query: 430 KIVKEIHEQLKAFW 443
+ +H+++ +W
Sbjct: 70 LAINCVHDRVVCWW 83
>gi|111548652 hypothetical protein LOC51057 isoform 2 [Homo sapiens]
Length = 746
Score = 32.0 bits (71), Expect = 2.1
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 7/74 (9%)
Query: 372 IIRTFLKEN--CFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERH 429
II +FL +N CF Q T K++ S+ L+ S D +F+ + ++ ERH
Sbjct: 174 IILSFLAQNKLCFIQFTKKME-----SSDVNKRLEKLSALDYKIFYYEIPGPINKTTERH 228
Query: 430 KIVKEIHEQLKAFW 443
+ +H+++ +W
Sbjct: 229 LAINCVHDRVVCWW 242
>gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]
Length = 893
Score = 31.6 bits (70), Expect = 2.7
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 9/69 (13%)
Query: 509 LYKSSDLPGGEFSTCFTVLQRN-----FIRSRPTKLKDLIRLVKHWYK-ECERKLKPKGS 562
+Y S LP + FT L FI SRP KD+++L++H Y +C LK
Sbjct: 195 IYLSGFLPKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKC---LKESTR 251
Query: 563 LPPKYALEL 571
L P + L++
Sbjct: 252 LYPVFFLKI 260
>gi|18254456 testis-specific gene A2 [Homo sapiens]
Length = 309
Score = 31.2 bits (69), Expect = 3.5
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 445 EKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYA 504
E+EEE E+ PKWKA ++ +L + L + + P +A G S+G P E A
Sbjct: 195 EEEEEEELVTVVPKWKATQITELALWTPTLPKKPTSTDGPGQDAPGAESAGE-PGEEAQA 253
Query: 505 GLIDLYKSSDL-PGGE 519
L D+ PG E
Sbjct: 254 LLEGFEGEMDMRPGDE 269
>gi|13376259 nucleoporin 85 [Homo sapiens]
Length = 656
Score = 31.2 bits (69), Expect = 3.5
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 7/76 (9%)
Query: 162 ELKRSLDK-TNASPGEFAVC--FTELQQKFFDNRPGK---LKDLILLIKHWHQQCQKKIK 215
E ++ L K +ASP +C +L + PG L +L L +HWH++C++ ++
Sbjct: 211 EARQMLSKEADASPASAGICRIMGDLMRTMPILSPGNTQTLTELELKWQHWHEECERYLQ 270
Query: 216 DLP-SLSPYALELLTV 230
D + SP+ LL +
Sbjct: 271 DSTFATSPHLESLLKI 286
>gi|28872780 cytosine-5-methyltransferase 3-like protein isoform 2
[Homo sapiens]
Length = 386
Score = 30.4 bits (67), Expect = 6.0
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 10/62 (16%)
Query: 438 QLKAFW-REKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGS 496
QLKAF+ RE E LE+ P W+ V SL + E S LG L SGS
Sbjct: 163 QLKAFYDRESENPLEMFETVPVWRRQPVRVLSLFEDIKKELTS---------LGFLESGS 213
Query: 497 TP 498
P
Sbjct: 214 DP 215
>gi|28872778 cytosine-5-methyltransferase 3-like protein isoform 1
[Homo sapiens]
Length = 387
Score = 30.4 bits (67), Expect = 6.0
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 10/62 (16%)
Query: 438 QLKAFW-REKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGS 496
QLKAF+ RE E LE+ P W+ V SL + E S LG L SGS
Sbjct: 163 QLKAFYDRESENPLEMFETVPVWRRQPVRVLSLFEDIKKELTS---------LGFLESGS 213
Query: 497 TP 498
P
Sbjct: 214 DP 215
>gi|58331272 zinc finger, CCHC domain containing 6 [Homo sapiens]
Length = 1495
Score = 30.4 bits (67), Expect = 6.0
Identities = 17/62 (27%), Positives = 26/62 (41%), Gaps = 1/62 (1%)
Query: 518 GEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAW 577
G + C T + KL L+ ++W K C +G LPP Y L+ I+
Sbjct: 412 GNENACLTTKHLTALGKLEPKLVPLVIAFRYWAKLCSIDRPEEGGLPP-YVFALMAIFFL 470
Query: 578 EQ 579
+Q
Sbjct: 471 QQ 472
>gi|33186882 testis serine protease 2 [Homo sapiens]
Length = 293
Score = 30.4 bits (67), Expect = 6.0
Identities = 16/64 (25%), Positives = 32/64 (50%), Gaps = 8/64 (12%)
Query: 20 IQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVL 79
+ +Y+ YEEC +I + +++ DV +++G+ G K +G+S G L
Sbjct: 222 VDQYIMCYEECNKIIQKALSSTKDV--------IIKGMVCGYKEQGKDSCQGDSGGRLAC 273
Query: 80 FFSD 83
++D
Sbjct: 274 EYND 277
>gi|33946311 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform C precursor [Homo sapiens]
Length = 927
Score = 30.4 bits (67), Expect = 6.0
Identities = 42/183 (22%), Positives = 69/183 (37%), Gaps = 16/183 (8%)
Query: 322 PNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENC 381
P + N LP P VL +P T L D F +C + ++ ++
Sbjct: 500 PAIFNSLPLPR-AVLASPCVATVTILDDDHAGIFTF--ECDTIHVSESIGVMEV----KV 552
Query: 382 FRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKA 441
R S A+ ++ T +GTA G D + K+ + K R KIV E
Sbjct: 553 LRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRVKIVDEEE----- 607
Query: 442 FWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPA--FNALGQLSSGSTPS 499
E++E ++ PKW + + L V + ++ + A +G+ G P
Sbjct: 608 --YERQENFFIALGEPKWMERGISALLLSPDVTDRKLTMEEEEAKRIAEMGKPVLGEHPK 665
Query: 500 PEV 502
EV
Sbjct: 666 LEV 668
>gi|188528616 testis specific, 10 [Homo sapiens]
Length = 698
Score = 30.0 bits (66), Expect = 7.8
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 12/111 (10%)
Query: 348 LDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQS-----TAKIQIVRGGSTAKGTA 402
L +K N+ +EQ+ A + EN RQS T K++++ + A+G
Sbjct: 399 LKNILKSEESENRQMMEQLRKANEDAENW--ENKARQSEADNNTLKLELIT--AEAEGNR 454
Query: 403 LKTGSDA---DLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEEL 450
LK D+ ++ N+ +SY SQ + HK V ++ E+L+ EK L
Sbjct: 455 LKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSAL 505
>gi|13376858 testis specific, 10 [Homo sapiens]
Length = 698
Score = 30.0 bits (66), Expect = 7.8
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 12/111 (10%)
Query: 348 LDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQS-----TAKIQIVRGGSTAKGTA 402
L +K N+ +EQ+ A + EN RQS T K++++ + A+G
Sbjct: 399 LKNILKSEESENRQMMEQLRKANEDAENW--ENKARQSEADNNTLKLELIT--AEAEGNR 454
Query: 403 LKTGSDA---DLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEEL 450
LK D+ ++ N+ +SY SQ + HK V ++ E+L+ EK L
Sbjct: 455 LKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSAL 505
>gi|239751222 PREDICTED: hypothetical protein XP_002347759 [Homo
sapiens]
Length = 95
Score = 30.0 bits (66), Expect = 7.8
Identities = 15/39 (38%), Positives = 20/39 (51%)
Query: 626 SQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWL 664
+QL + R +L PA+P D GG + E KEWL
Sbjct: 28 TQLCQRRGTVLAPAQPRADSGGSGEVVQSQSSVERKEWL 66
>gi|239745712 PREDICTED: hypothetical protein XP_002343531 [Homo
sapiens]
Length = 95
Score = 30.0 bits (66), Expect = 7.8
Identities = 15/39 (38%), Positives = 20/39 (51%)
Query: 626 SQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWL 664
+QL + R +L PA+P D GG + E KEWL
Sbjct: 28 TQLCQRRGTVLAPAQPRADSGGSGEVVQSQSSVERKEWL 66
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,095,251
Number of Sequences: 37866
Number of extensions: 1462770
Number of successful extensions: 3768
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3657
Number of HSP's gapped (non-prelim): 43
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.