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Search of human proteins with 73747840
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73747840 LON peptidase N-terminal domain and ring finger 3
isoform 1 [Homo sapiens]
(759 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is... 1546 0.0
gi|37622896 LON peptidase N-terminal domain and ring finger 3 is... 1446 0.0
gi|148528975 LON peptidase N-terminal domain and ring finger 2 [... 563 e-160
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 496 e-140
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 66 1e-10
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 65 2e-10
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 65 3e-10
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 65 3e-10
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 65 3e-10
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 64 4e-10
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 64 7e-10
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 62 3e-09
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 59 1e-08
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 59 1e-08
gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens] 57 5e-08
gi|7110679 tetratricopeptide repeat domain 33 [Homo sapiens] 57 8e-08
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 56 1e-07
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 55 2e-07
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens] 55 2e-07
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 55 3e-07
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 54 4e-07
gi|24025688 ligand of numb-protein X 2 [Homo sapiens] 54 4e-07
gi|31377566 ring finger protein 168 [Homo sapiens] 54 5e-07
gi|21071052 helicase-like transcription factor [Homo sapiens] 54 5e-07
gi|21071054 helicase-like transcription factor [Homo sapiens] 54 5e-07
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 54 7e-07
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens] 53 1e-06
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens] 53 1e-06
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 52 2e-06
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 52 2e-06
>gi|73747840 LON peptidase N-terminal domain and ring finger 3
isoform 1 [Homo sapiens]
Length = 759
Score = 1546 bits (4004), Expect = 0.0
Identities = 759/759 (100%), Positives = 759/759 (100%)
Query: 1 MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP 60
MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP
Sbjct: 1 MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP 60
Query: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA
Sbjct: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
Query: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL
Sbjct: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
Query: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240
CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP
Sbjct: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240
Query: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA
Sbjct: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
Query: 301 EIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPH 360
EIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPH
Sbjct: 301 EIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPH 360
Query: 361 CSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK 420
CSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK
Sbjct: 361 CSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK 420
Query: 421 RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTT 480
RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTT
Sbjct: 421 RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTT 480
Query: 481 PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRK 540
PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRK
Sbjct: 481 PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRK 540
Query: 541 LYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGD 600
LYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGD
Sbjct: 541 LYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGD 600
Query: 601 PVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQ 660
PVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQ
Sbjct: 601 PVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQ 660
Query: 661 GEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWM 720
GEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWM
Sbjct: 661 GEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWM 720
Query: 721 LAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 759
LAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN
Sbjct: 721 LAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 759
>gi|37622896 LON peptidase N-terminal domain and ring finger 3
isoform 2 [Homo sapiens]
Length = 718
Score = 1446 bits (3743), Expect = 0.0
Identities = 718/759 (94%), Positives = 718/759 (94%), Gaps = 41/759 (5%)
Query: 1 MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP 60
MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP
Sbjct: 1 MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSP 60
Query: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA
Sbjct: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
Query: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL
Sbjct: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
Query: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240
CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP
Sbjct: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240
Query: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA
Sbjct: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
Query: 301 EIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPH 360
EIACKLRPMGFK DNLELPH
Sbjct: 301 EIACKLRPMGFK-----------------------------------------DNLELPH 319
Query: 361 CSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK 420
CSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK
Sbjct: 320 CSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK 379
Query: 421 RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTT 480
RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTT
Sbjct: 380 RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTT 439
Query: 481 PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRK 540
PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRK
Sbjct: 440 PCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRK 499
Query: 541 LYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGD 600
LYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGD
Sbjct: 500 LYEEEMEELSNLNKNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGD 559
Query: 601 PVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQ 660
PVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQ
Sbjct: 560 PVKGFAEYGCILEIRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQ 619
Query: 661 GEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWM 720
GEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWM
Sbjct: 620 GEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWM 679
Query: 721 LAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 759
LAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN
Sbjct: 680 LAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN 718
>gi|148528975 LON peptidase N-terminal domain and ring finger 2
[Homo sapiens]
Length = 754
Score = 563 bits (1452), Expect = e-160
Identities = 318/730 (43%), Positives = 428/730 (58%), Gaps = 71/730 (9%)
Query: 61 GTSTPESKVLLTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEA 120
G + P+ + L DALA GR+ EAL +R + L E+LE+L L V
Sbjct: 52 GLAQPDRGLCLRLGDALARAGRLPEALGAFRGAARLGALRPEELEELAGGLVRAV----G 107
Query: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
L P + A E G A A D C +C L PV+L CG T CK
Sbjct: 108 LRDRPLSAENPGGEPEAPGEGGPAPEPRAPR--DLLGCPRCRRLLHKPVTLPCGLTVCKR 165
Query: 181 CLERGRAADRRCALCGVKLSALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPGP 240
C+E G A P RVNVVLSGLL K FP
Sbjct: 166 CVEPGPAR-------------------------------PQVRRVNVVLSGLLEKCFPAE 194
Query: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
R +L + L R++Q EAALL+ ++A++LAP+D+ L R+++Y T++++E AL DA
Sbjct: 195 CRLRRLAGQARSLQRQQQPEAALLRCDQALELAPDDNSLLLLRAELYLTMKNYEQALQDA 254
Query: 301 EIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLEL-- 358
AC+ P+ K H KAQAL+ LG+ +E L+EFLYC++L+ + + EAQ+ E+
Sbjct: 255 SAACQNEPLLIKGHQVKAQALSGLGRSKEVLKEFLYCLALNPECNSVKKEAQKVMCEVLF 314
Query: 359 -------PHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASS 411
+ +S ++ + G S M+ + +G ++ E+ + T+
Sbjct: 315 SATANVHENLTSSIQSRLKAQGHSHMNAQALLEEGDAGSSENSSEKSDMLGNTNSSVLYF 374
Query: 412 KTGKCQEKKRKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLA------------- 458
G E+ +K +ES T P+ K+ P D D P L+ P
Sbjct: 375 ILGLHFEEDKK--ALESILPTA-PSAGLKRQFPDDVEDAPDLNAPGKIPKKDLSLQRSPN 431
Query: 459 ---------SFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLS 509
S D +D ECALCMRL +EPVTTPCGHTFCLKCLERCLDH CPLCKD LS
Sbjct: 432 SETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPHCPLCKDKLS 491
Query: 510 QCLASRKYSKNVIMEELIAKFLPEELKERRKLYEEEMEELSNLNKNVPIFVCTMAYPTVP 569
+ LASR ++ V+ EELI ++LP+EL +R+++Y+EEM ELSNL ++VPIFVC MA+PTVP
Sbjct: 492 ELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSELSNLTRDVPIFVCAMAFPTVP 551
Query: 570 CPLHIFEPCYRLMIRRCIETGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDS 629
CPLH+FEP YRLMIRRC+ETGT++FGMCL G +EYGC+LEI++V+ F DG SVVD+
Sbjct: 552 CPLHVFEPRYRLMIRRCMETGTKRFGMCLSAEHAGLSEYGCMLEIKDVRTFPDGSSVVDA 611
Query: 630 IGKRRFRVLHQSQRDGYNTADIEYIEDQKVQGEDCAELMGLHNCVYQQASLWFHSLKLSL 689
IG RFRVL RDGYNTADIEY+ED+KV+G + EL LH+ V+QQ+ WF SL+ +
Sbjct: 612 IGISRFRVLSHRHRDGYNTADIEYLEDEKVEGPEYEELAALHDSVHQQSVSWFASLQDRM 671
Query: 690 KNRILNHFGPMPEKDADPQMNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRR 749
K +IL+HFG MP+++ +PQ NP+GPAW WW+LAVLPLE +AQL L M SLK+RL IRR
Sbjct: 672 KEQILSHFGVMPDREPEPQSNPSGPAWSWWILAVLPLERKAQLAILGMTSLKERLLAIRR 731
Query: 750 VLAFISRNQN 759
+L I+R N
Sbjct: 732 ILVIITRKMN 741
>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
sapiens]
Length = 773
Score = 496 bits (1277), Expect = e-140
Identities = 300/747 (40%), Positives = 407/747 (54%), Gaps = 78/747 (10%)
Query: 68 KVLLTQADALASRGRIREALEVYRQLSERQQLVA-EQLEQLVRCLAEKVPQGEALAPAPP 126
++LL + + LA G ++ ALE + R E L LV CL L
Sbjct: 49 ELLLRRGELLALGGHLKGALEAFAAALRRGAPARPECLGALVDCLVFNYRLRHGL----- 103
Query: 127 DEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKLCLERGR 186
G AA GA A +C C GFLS+PV++ CGH++C+ CL R
Sbjct: 104 -------GWSAAPVAGADGGAGGL-----LRCLGCRGFLSEPVTVPCGHSYCRRCLRREL 151
Query: 187 AADRRCALCGVKLSALMVATGRARGARRAGQQPPP--------PLRVNVVLSGLLGKLFP 238
A RC LC +L AT A A +PPP R +VVL+ L K FP
Sbjct: 152 RA--RCRLCRDRLPP---ATASATDAEGTAPRPPPLAAAIAASDFRTSVVLNHLAEKWFP 206
Query: 239 GPARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALH 298
G ++ L + + AL EA++ P+D ++ R++ Y L+ + A+
Sbjct: 207 GQRERARAAGRLGELLHQGRYREALAAACEALRAEPSDLIVKIYRAESYAGLQEFKAAIE 266
Query: 299 DAEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLEL 358
D P + +FRK + L G + +AL+ FL C++LD A+ + Q+ +L
Sbjct: 267 DLNAVLFQLPDWPEVYFRKGKVLCDAGFLGDALQLFLQCLALDEDFAPAKLQVQKILCDL 326
Query: 359 PHCSSQEEAAARGDGSSL-------MDPAKVKGDGQQHHMKDQEEEEEKWDATSP----- 406
+ +E SSL D V + Q + ++ EE + TS
Sbjct: 327 LLPENLKEGLKESSWSSLPCTKNRPFDFHSVMEESQSLNEPSPKQSEEIPEVTSEPVKGS 386
Query: 407 -----------------------KAASSKTGKCQEK----KRKHCQIESQ---EETGMPN 436
+ +S QEK KRK +E E G N
Sbjct: 387 LNRAQSAQSINSTEMPAREDCLKRVSSEPVLSVQEKGVLLKRKLSLLEQDVIVNEDGR-N 445
Query: 437 KASKQDPPTDQGDKPALS---LPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLER 493
K KQ ++ +L+ +P D SD EC+LCMRLF+EPVTTPCGH+FC CLER
Sbjct: 446 KLKKQGETPNEVCMFSLAYGDIPEELIDVSDFECSLCMRLFFEPVTTPCGHSFCKNCLER 505
Query: 494 CLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRKLYEEEMEELSNLN 553
CLDH CPLCK+ L + LA R+Y ++EELI K+LP+EL ER+K+Y+EE ELS+L
Sbjct: 506 CLDHAPYCPLCKESLKEYLADRRYCVTQLLEELIVKYLPDELSERKKIYDEETAELSHLT 565
Query: 554 KNVPIFVCTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGDPVKGFAEYGCILE 613
KNVPIFVCTMAYPTVPCPLH+FEP YRLMIRR I+TGT+QFGMC+ D FA+YGC+L+
Sbjct: 566 KNVPIFVCTMAYPTVPCPLHVFEPRYRLMIRRSIQTGTKQFGMCVSDTQNSFADYGCMLQ 625
Query: 614 IRNVQFFADGRSVVDSIGKRRFRVLHQSQRDGYNTADIEYIEDQKVQGED-CAELMGLHN 672
IRNV F DGRSVVD++G +RFRVL + +DGY TADIEY+ED KV+ ED L LH+
Sbjct: 626 IRNVHFLPDGRSVVDTVGGKRFRVLKRGMKDGYCTADIEYLEDVKVENEDEIKNLRELHD 685
Query: 673 CVYQQASLWFHSLKLSLKNRILNHFGPMPEKDADPQMNPNGPAWCWWMLAVLPLESRAQL 732
VY QA WF +L+ +++IL HFG MPE++ + Q PNGPAWCWW+LAVLP++ R QL
Sbjct: 686 LVYSQACSWFQNLRDRFRSQILQHFGSMPEREENLQAAPNGPAWCWWLLAVLPVDPRYQL 745
Query: 733 PFLAMRSLKDRLNGIRRVLAFISRNQN 759
L+M+SLK+RL I+ +L + SR+Q+
Sbjct: 746 SVLSMKSLKERLTKIQHILTYFSRDQS 772
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 66.2 bits (160), Expect = 1e-10
Identities = 40/111 (36%), Positives = 63/111 (56%), Gaps = 3/111 (2%)
Query: 238 PGPARASQLRHEGNRLYRERQVEAALLKYNEAVKL--APNDH-LLYSNRSQIYFTLESHE 294
PG + QLR EGN L++ AL Y +A+ L P D +L+ NR+ + LE ++
Sbjct: 16 PGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYD 75
Query: 295 NALHDAEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNK 345
A +A A + KA +R++QAL LG++++A+ + CVSL+ KNK
Sbjct: 76 KAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNK 126
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 65.1 bits (157), Expect = 2e-10
Identities = 41/134 (30%), Positives = 68/134 (50%), Gaps = 5/134 (3%)
Query: 242 RASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAE 301
+A QL+ EGN +E AA+ Y +A++L PN+ + Y NR+ L + +A+ D E
Sbjct: 84 KADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDAIKDCE 143
Query: 302 IACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPHC 361
A + KA+ R AL L K EEA+ + + LD +N ++ + NL++
Sbjct: 144 KAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEN-----DSYKSNLKIAEQ 198
Query: 362 SSQEEAAARGDGSS 375
+E ++ G G S
Sbjct: 199 KLREVSSPTGTGLS 212
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 64.7 bits (156), Expect = 3e-10
Identities = 48/158 (30%), Positives = 77/158 (48%), Gaps = 13/158 (8%)
Query: 213 RRAGQQPPPPLRVNVVLSGLLGKLFP-GP----ARASQLRHEGNRLYRERQVEAALLKYN 267
RR + PP + + + +G+ P GP A + + N+ + A++ YN
Sbjct: 23 RREPESPPASAPIPLFGADTIGQRSPDGPVLSKAEFVEKVRQSNQACHDGDFHTAIVLYN 82
Query: 268 EAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEIACKLRPMGFKAHFRKAQALATLGKV 327
EA+ + P + +LYSNRS Y ++ ++ AL DA A L P KA+FR+ AL LG+
Sbjct: 83 EALAVDPQNCILYSNRSAAYMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRH 142
Query: 328 EEALREFLYCVSLDGKN--------KRARCEAQRDNLE 357
+AL F ++ D K+ + A RD+LE
Sbjct: 143 ADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDSLE 180
>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
Length = 929
Score = 64.7 bits (156), Expect = 3e-10
Identities = 39/119 (32%), Positives = 65/119 (54%), Gaps = 3/119 (2%)
Query: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLL---YSNRSQIYFTLESHENALHD 299
A QL+ EGNR ++ + +AA Y++A+KL + LL Y NR+ ES+ A D
Sbjct: 6 AVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAASD 65
Query: 300 AEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLEL 358
A A + KA +R+ QAL LGK+++A ++ C +L+ +N+ + +R N +
Sbjct: 66 ASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
Length = 931
Score = 64.7 bits (156), Expect = 3e-10
Identities = 39/119 (32%), Positives = 65/119 (54%), Gaps = 3/119 (2%)
Query: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLL---YSNRSQIYFTLESHENALHD 299
A QL+ EGNR ++ + +AA Y++A+KL + LL Y NR+ ES+ A D
Sbjct: 6 AVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAASD 65
Query: 300 AEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLEL 358
A A + KA +R+ QAL LGK+++A ++ C +L+ +N+ + +R N +
Sbjct: 66 ASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 64.3 bits (155), Expect = 4e-10
Identities = 36/114 (31%), Positives = 62/114 (54%)
Query: 242 RASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAE 301
RA +L+ + N ++ + E A+ Y++A++L P++ + Y NRS Y E + AL DA
Sbjct: 27 RAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDAT 86
Query: 302 IACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDN 355
A +L K ++R+A + LGK ALR++ V + +K A+ + Q N
Sbjct: 87 RAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECN 140
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 63.5 bits (153), Expect = 7e-10
Identities = 34/93 (36%), Positives = 53/93 (56%)
Query: 242 RASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAE 301
+ ++L+ +GN+ ++ AL Y+EA+KL P++H+LYSNRS Y ++ A D
Sbjct: 3 QVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGC 62
Query: 302 IACKLRPMGFKAHFRKAQALATLGKVEEALREF 334
L+P K + RKA AL L + EEA R +
Sbjct: 63 KTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTY 95
Score = 60.1 bits (144), Expect = 8e-09
Identities = 37/114 (32%), Positives = 55/114 (48%)
Query: 240 PARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHD 299
P A + +++GN +++ A+ Y EA+K P D LYSNR+ Y L + AL D
Sbjct: 357 PDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKD 416
Query: 300 AEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQR 353
E +L P K + RKA AL + +A+ + + LD K A QR
Sbjct: 417 CEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGYQR 470
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 61.6 bits (148), Expect = 3e-09
Identities = 38/104 (36%), Positives = 60/104 (57%), Gaps = 3/104 (2%)
Query: 245 QLRHEGNRLYRERQVEAALLKYNEAVKL--APNDH-LLYSNRSQIYFTLESHENALHDAE 301
QLR EGN L++ AL Y +A+ L P D +L+ NR+ + LE ++ A +A
Sbjct: 8 QLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAETEAS 67
Query: 302 IACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNK 345
A + KA +R++QAL LG++++A+ + CVSL+ KNK
Sbjct: 68 KAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNK 111
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 59.3 bits (142), Expect = 1e-08
Identities = 70/299 (23%), Positives = 113/299 (37%), Gaps = 36/299 (12%)
Query: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEI 302
A +L+ +GNRL+ R+ A Y A+ P + Y+NR+ Y ++ HE AL D
Sbjct: 26 AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRR 85
Query: 303 ACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPHCS 362
A +L KAHF Q + +EA+ NL+ +
Sbjct: 86 ALELDGQSVKAHFFLGQCQLEMESYDEAIA----------------------NLQRAYSL 123
Query: 363 SQEEAAARGDG--SSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK 420
++E+ GD S+L K + + + QE E + S A+ + + +E +
Sbjct: 124 AKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSY--LSRLIAAERERELEECQ 181
Query: 421 RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPL----ASFDASDLECA-LCMRLFY 475
R H E + D L + D D C + L
Sbjct: 182 RNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMR 241
Query: 476 EPVTTPCGHTFCLKCLERCLDHNAKC-PLCKDGLSQCLASRKYSKNVIMEELIAKFLPE 533
EP TP G T+ K +E L P+ + L+Q + N+ M+E+I F+ E
Sbjct: 242 EPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQ----EQLIPNLAMKEVIDAFISE 296
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 59.3 bits (142), Expect = 1e-08
Identities = 39/131 (29%), Positives = 65/131 (49%), Gaps = 5/131 (3%)
Query: 241 ARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDA 300
A A +L+ EGN + EAA+ Y +A++L P + + + NR+ Y L ++ A+ D
Sbjct: 89 AEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAGAVQDC 148
Query: 301 EIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPH 360
E A + P KA+ R AL++L K EA+ + + LD N E + NL++
Sbjct: 149 ERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDN-----ETYKSNLKIAE 203
Query: 361 CSSQEEAAARG 371
+E + G
Sbjct: 204 LKLREAPSPTG 214
>gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens]
Length = 977
Score = 57.4 bits (137), Expect = 5e-08
Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 12/94 (12%)
Query: 249 EGNRLYRERQVEAALLKYNEAVKLA----------PNDHL--LYSNRSQIYFTLESHENA 296
EGN L+RE+ + AL++Y E + +A P + L L+ NR+ YFT+ +E A
Sbjct: 42 EGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLHVNRAACYFTMGLYEKA 101
Query: 297 LHDAEIACKLRPMGFKAHFRKAQALATLGKVEEA 330
L D+E A L +A FRKA+AL LG+ +EA
Sbjct: 102 LEDSEKALGLDSESIRALFRKARALNELGRHKEA 135
>gi|7110679 tetratricopeptide repeat domain 33 [Homo sapiens]
Length = 262
Score = 56.6 bits (135), Expect = 8e-08
Identities = 30/93 (32%), Positives = 53/93 (56%)
Query: 242 RASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAE 301
++ QL+ EG L ++ A+ K++EA++L PND LY +SQ+ +L A+H AE
Sbjct: 58 KSKQLKDEGASLAENKRYREAIQKWDEALQLTPNDATLYEMKSQVLMSLHEMFPAVHAAE 117
Query: 302 IACKLRPMGFKAHFRKAQALATLGKVEEALREF 334
+A + P +++ +A LG++ A+R F
Sbjct: 118 MAVQQNPHSWESWQTLGRAQLGLGEIILAIRSF 150
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 56.2 bits (134), Expect = 1e-07
Identities = 32/92 (34%), Positives = 49/92 (53%), Gaps = 7/92 (7%)
Query: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEI 302
A L+ +GN + E E A+L+Y+E ++ + +LY+NR+Q Y LE +E AL D E
Sbjct: 106 ADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEW 165
Query: 303 ACKLRPMGFKAHFRKAQALATLGKVEEALREF 334
A K KA+F +GK AL+ +
Sbjct: 166 ALKCDEKCTKAYFH-------MGKANLALKNY 190
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 55.5 bits (132), Expect = 2e-07
Identities = 26/74 (35%), Positives = 38/74 (51%)
Query: 462 ASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNV 521
A +L C++C+ F EPVTTPCGH FC CL LC + A + KN
Sbjct: 8 AEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNT 67
Query: 522 IMEELIAKFLPEEL 535
++ ++ +FL +L
Sbjct: 68 VLCNVVEQFLQADL 81
Score = 30.8 bits (68), Expect = 4.9
Identities = 14/38 (36%), Positives = 16/38 (42%)
Query: 158 CRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALC 195
C C +PV+ CGH FC CL A LC
Sbjct: 13 CSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLC 50
>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
Length = 676
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/165 (26%), Positives = 75/165 (45%), Gaps = 16/165 (9%)
Query: 240 PARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLE---SHENA 296
P +++ + N + +Q A+ Y++AV+ AP++ +LY NR+ Y + H +A
Sbjct: 358 PPYLERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDA 417
Query: 297 LHDAEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNK------RARCE 350
L D A L P KAHFR A+ L L V EAL C+ D K K + C+
Sbjct: 418 LRDCLKAISLNPCHLKAHFRLARCLFELKYVAEALE----CLD-DFKGKFPEQAHSSACD 472
Query: 351 AQRDNLELPHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQE 395
A ++ S + +G G P +++ ++ + + E
Sbjct: 473 ALGRDITAALFSKNDGEEKKGPGGGA--PVRLRSTSRKDSISEDE 515
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 54.7 bits (130), Expect = 3e-07
Identities = 31/113 (27%), Positives = 51/113 (45%)
Query: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEI 302
A + +GN Y ++ A Y +A+ + P + Y NR+ L AL DA+
Sbjct: 28 AETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQQ 87
Query: 303 ACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDN 355
+ +L + H R+ + +LG A R F + LD KN +A+ E + N
Sbjct: 88 SVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNAN 140
Score = 48.1 bits (113), Expect = 3e-05
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 247 RHEGNRLYRERQVEAALLKYNEAVKLAPND----HLLYSNRSQIYFTLESHENALHDAEI 302
+ +GN+ ++E + A Y EA+ + PN+ LY NR + L ++A+ D
Sbjct: 260 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTN 319
Query: 303 ACKLRPMGFKAHFRKAQALATLGKVEEALREF 334
A KL KA+ R+AQ + EEA+R++
Sbjct: 320 AVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDY 351
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 54.3 bits (129), Expect = 4e-07
Identities = 53/228 (23%), Positives = 89/228 (39%), Gaps = 16/228 (7%)
Query: 121 LAPAPPDEGSTASGTVAAEETGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKL 180
+A + P E + + V + +G A G + + P+ L G +
Sbjct: 1 MAASKPVEAAVVAAAVPSSGSGVGGGGTAGPGTGGLPRWQLALAVGAPLLLGAGAIYLWS 60
Query: 181 CLERGRAADRRCALCGVKL-SALMVATGRARGARRAGQQPPPPLRVNVVLSGLLGKLFPG 239
+R R A R G+K S GRA A +G P +++
Sbjct: 61 RQQRRREARGRGDASGLKRNSERKTPEGRASPAPGSGHPEGPGAHLDM----------NS 110
Query: 240 PARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDH-----LLYSNRSQIYFTLESHE 294
RA +++GN+ ++ + E A+ Y EA+ L P + Y NR+ + L+ +
Sbjct: 111 LDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWK 170
Query: 295 NALHDAEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDG 342
D A +L P KA FR+A+A L +E L + L+G
Sbjct: 171 EVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILEG 218
Score = 30.8 bits (68), Expect = 4.9
Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 283 RSQIYFTLESHENALHDAEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDG 342
R +Y + + D +A + P + + Q L +VEEA+ +F C+ L
Sbjct: 373 RGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRP 432
Query: 343 KNKRA---RCEAQRDNLELPHCSSQEEAAARG 371
++ A +C A + SSQ +AA +G
Sbjct: 433 ESALAQAQKCFALYRQAYTGNNSSQIQAAMKG 464
>gi|24025688 ligand of numb-protein X 2 [Homo sapiens]
Length = 690
Score = 54.3 bits (129), Expect = 4e-07
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 464 DLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIM 523
DL C +C++ +P+ TPCGHTFC KCL L CPL + L L + ++++
Sbjct: 47 DLVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKK---SSILV 103
Query: 524 EELIAKFL 531
+L+ K L
Sbjct: 104 HKLLDKLL 111
Score = 33.1 bits (74), Expect = 0.98
Identities = 15/32 (46%), Positives = 16/32 (50%)
Query: 151 EVWDGFKCRKCHGFLSDPVSLSCGHTFCKLCL 182
EV D C C L P+ CGHTFC CL
Sbjct: 43 EVDDDLVCHICLQPLLQPLDTPCGHTFCYKCL 74
>gi|31377566 ring finger protein 168 [Homo sapiens]
Length = 571
Score = 53.9 bits (128), Expect = 5e-07
Identities = 29/87 (33%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 463 SDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDH-NAKCPLCKDGLSQCL---ASRKYS 518
S+ +C +CM + EPVT PC HT C C + ++ + CP C+ +S R
Sbjct: 12 SECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSL 71
Query: 519 KNVIMEELIAKFLPEELKERRKLYEEE 545
NV + +I K P E K R E E
Sbjct: 72 VNVELWTIIQKHYPRECKLRASGQESE 98
Score = 33.9 bits (76), Expect = 0.58
Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLCLERG-RAADRRCALCGVKLSA 201
+C C L +PV+L C HT CK C + A C C ++S+
Sbjct: 15 QCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSS 60
>gi|21071052 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 53.9 bits (128), Expect = 5e-07
Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 18/122 (14%)
Query: 436 NKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCL 495
N S D P + K + L SD ECA+C+ PV T C H FC C+ + +
Sbjct: 729 NGPSGNDTPEELRKKLIRKMKLILSSGSDEECAICLDSLTVPVITHCAHVFCKPCICQVI 788
Query: 496 DH---NAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEEL-KERRKLYEEEMEELSN 551
+ +AKCPLC +N I E+ + + PEEL ++ K + E S
Sbjct: 789 QNEQPHAKCPLC--------------RNDIHEDNLLECPPEELARDSEKKSDMEWTSSSK 834
Query: 552 LN 553
+N
Sbjct: 835 IN 836
Score = 30.0 bits (66), Expect = 8.3
Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLCL---ERGRAADRRCALC 195
+C C L+ PV C H FCK C+ + +C LC
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLC 800
>gi|21071054 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 53.9 bits (128), Expect = 5e-07
Identities = 37/122 (30%), Positives = 54/122 (44%), Gaps = 18/122 (14%)
Query: 436 NKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCL 495
N S D P + K + L SD ECA+C+ PV T C H FC C+ + +
Sbjct: 729 NGPSGNDTPEELRKKLIRKMKLILSSGSDEECAICLDSLTVPVITHCAHVFCKPCICQVI 788
Query: 496 DH---NAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEEL-KERRKLYEEEMEELSN 551
+ +AKCPLC +N I E+ + + PEEL ++ K + E S
Sbjct: 789 QNEQPHAKCPLC--------------RNDIHEDNLLECPPEELARDSEKKSDMEWTSSSK 834
Query: 552 LN 553
+N
Sbjct: 835 IN 836
Score = 30.0 bits (66), Expect = 8.3
Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLCL---ERGRAADRRCALC 195
+C C L+ PV C H FCK C+ + +C LC
Sbjct: 759 ECAICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLC 800
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 53.5 bits (127), Expect = 7e-07
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 9/104 (8%)
Query: 439 SKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKCLERCLDHN 498
+K++ Q K + + ++L+C +C F E VT C H+FC C+ +
Sbjct: 375 TKEEKEKMQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRK 434
Query: 499 AKCPLCKDGLSQCLASRKYSKNVIMEELIAKF---LPEELKERR 539
+CP+C+ + S+ YS ++++ I K L E+KERR
Sbjct: 435 IECPICRKDIK----SKTYS--LVLDNCINKMVNNLSSEVKERR 472
Score = 33.5 bits (75), Expect = 0.75
Identities = 11/39 (28%), Positives = 19/39 (48%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALC 195
+C C + + V+L+C H+FC C+ C +C
Sbjct: 402 QCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPIC 440
>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 52.8 bits (125), Expect = 1e-06
Identities = 26/87 (29%), Positives = 48/87 (55%)
Query: 246 LRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEIACK 305
++ +GN + + + + A++ Y A++ P ++LLY NR+ + NAL D + A
Sbjct: 234 MKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATI 293
Query: 306 LRPMGFKAHFRKAQALATLGKVEEALR 332
L+ K H+R AL+ LG+ + AL+
Sbjct: 294 LKNTWPKGHYRYCDALSMLGEYDWALQ 320
>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 52.8 bits (125), Expect = 1e-06
Identities = 26/87 (29%), Positives = 48/87 (55%)
Query: 246 LRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEIACK 305
++ +GN + + + + A++ Y A++ P ++LLY NR+ + NAL D + A
Sbjct: 234 MKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATI 293
Query: 306 LRPMGFKAHFRKAQALATLGKVEEALR 332
L+ K H+R AL+ LG+ + AL+
Sbjct: 294 LKNTWPKGHYRYCDALSMLGEYDWALQ 320
>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
Length = 1884
Score = 52.4 bits (124), Expect = 2e-06
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 465 LECALCMRLFYEPVTTPCGHTFCLKCLERCLDHN---AKCPLCKDGLSQCLASRKYSKNV 521
LEC +C+ L EPV+T C H FC C+ + L+ ++CPLCK+ +++ +
Sbjct: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81
Query: 522 IMEELI 527
++EEL+
Sbjct: 82 LVEELL 87
Score = 34.3 bits (77), Expect = 0.44
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLC---LERGRAADRRCALC 195
+C C + +PVS C H FCK C L + +C LC
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLC 64
>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
Length = 699
Score = 52.4 bits (124), Expect = 2e-06
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 465 LECALCMRLFYEPVTTPCGHTFCLKCLERCLDHN---AKCPLCKDGLSQCLASRKYSKNV 521
LEC +C+ L EPV+T C H FC C+ + L+ ++CPLCK+ +++ +
Sbjct: 22 LECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQ 81
Query: 522 IMEELI 527
++EEL+
Sbjct: 82 LVEELL 87
Score = 34.3 bits (77), Expect = 0.44
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 157 KCRKCHGFLSDPVSLSCGHTFCKLC---LERGRAADRRCALC 195
+C C + +PVS C H FCK C L + +C LC
Sbjct: 23 ECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLC 64
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,782,662
Number of Sequences: 37866
Number of extensions: 1599569
Number of successful extensions: 10894
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 313
Number of HSP's successfully gapped in prelim test: 248
Number of HSP's that attempted gapping in prelim test: 9719
Number of HSP's gapped (non-prelim): 1335
length of query: 759
length of database: 18,247,518
effective HSP length: 110
effective length of query: 649
effective length of database: 14,082,258
effective search space: 9139385442
effective search space used: 9139385442
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.