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Search of human proteins with 72534838
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|72534838 sorting nexin 6B [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72534838 sorting nexin 6B [Homo sapiens] 791 0.0
gi|88703041 sorting nexin 6 isoform b [Homo sapiens] 555 e-158
gi|23111047 sorting nexin 5 [Homo sapiens] 505 e-143
gi|7657599 sorting nexin 5 [Homo sapiens] 505 e-143
gi|88703043 sorting nexin 6 isoform a [Homo sapiens] 398 e-111
gi|23111038 sorting nexin 2 [Homo sapiens] 100 2e-21
gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 92 1e-18
gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 92 1e-18
gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 80 3e-15
gi|153791707 sorting nexin family member 30 [Homo sapiens] 53 4e-07
gi|23111055 sorting nexin 7 isoform b [Homo sapiens] 50 4e-06
gi|194294540 sorting nexin 7 isoform a [Homo sapiens] 50 4e-06
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens] 37 0.032
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens] 37 0.032
gi|23111030 sorting nexin 12 [Homo sapiens] 37 0.041
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 36 0.071
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 36 0.071
gi|4507143 sorting nexin 3 isoform a [Homo sapiens] 36 0.071
gi|117553613 coiled-coil domain containing 151 [Homo sapiens] 35 0.092
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo... 35 0.16
gi|51093830 bicaudal D homolog 1 isoform 2 [Homo sapiens] 33 0.46
gi|51039802 bicaudal D homolog 1 isoform 1 [Homo sapiens] 33 0.46
gi|110735404 protein tyrosine phosphatase, receptor type, U isof... 32 1.0
gi|110735406 protein tyrosine phosphatase, receptor type, U isof... 32 1.0
gi|110735402 protein tyrosine phosphatase, receptor type, U isof... 32 1.0
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 32 1.0
gi|81295809 pericentrin [Homo sapiens] 32 1.3
gi|224586875 coiled-coil domain containing 65 [Homo sapiens] 32 1.3
gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo sapi... 31 1.7
gi|57863310 stromal antigen 3 [Homo sapiens] 31 1.7
>gi|72534838 sorting nexin 6B [Homo sapiens]
Length = 403
Score = 791 bits (2043), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 METYAEVGKEGKPSCASVDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSV 60
METYAEVGKEGKPSCASVDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSV
Sbjct: 1 METYAEVGKEGKPSCASVDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSV 60
Query: 61 VRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMK 120
VRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMK
Sbjct: 61 VRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMK 120
Query: 121 QELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGG 180
QELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGG
Sbjct: 121 QELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGG 180
Query: 181 FLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLAD 240
FLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLAD
Sbjct: 181 FLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLAD 240
Query: 241 DYIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDS 300
DYIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDS
Sbjct: 241 DYIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDS 300
Query: 301 QAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELM 360
QAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELM
Sbjct: 301 QAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELM 360
Query: 361 DFKSRRVSSFRKNLIELAELELKHAKASTLILRNTLVALKGEP 403
DFKSRRVSSFRKNLIELAELELKHAKASTLILRNTLVALKGEP
Sbjct: 361 DFKSRRVSSFRKNLIELAELELKHAKASTLILRNTLVALKGEP 403
>gi|88703041 sorting nexin 6 isoform b [Homo sapiens]
Length = 418
Score = 555 bits (1431), Expect = e-158
Identities = 272/386 (70%), Positives = 333/386 (86%), Gaps = 3/386 (0%)
Query: 17 SVDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVE 76
+VDLQ D++LQV+ISDA+SERDKVKFTV TKS LP+F Q EFSVVRQHEEFIWLHD++VE
Sbjct: 35 NVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVE 94
Query: 77 NEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVA 136
NE+YAG IIPPAPPRPDF+ASREKLQKLGEG+ S+T+EEF KMKQELEAEYLAIFKKTVA
Sbjct: 95 NEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVA 154
Query: 137 MHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITG 196
MHEVFL R+AAHP LRRD NF VFLEY QDLSVRGKN+KE L F +N+VKSAD ++
Sbjct: 155 MHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIV-- 212
Query: 197 MSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQE 256
SG+K+VDDFFEHERTFLLEYH R++DA ++DR+ R+HK ADDY I ++L +LGTQ+
Sbjct: 213 -SGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQD 271
Query: 257 VNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALAD 316
+ FLK++ELF++ RK+E RV++DEDLKLSD+L+YY+R+SQAAKDLLYRR R+L D
Sbjct: 272 STDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVD 331
Query: 317 YENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIE 376
YENANKALDKAR +N++V AE+ QQLCCQ+FE++S+SAKQEL+DFK+RRV++FRKNL+E
Sbjct: 332 YENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVE 391
Query: 377 LAELELKHAKASTLILRNTLVALKGE 402
LAELELKHAK + +L+N L L G+
Sbjct: 392 LAELELKHAKGNLQLLQNCLAVLNGD 417
>gi|23111047 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 505 bits (1301), Expect = e-143
Identities = 243/384 (63%), Positives = 317/384 (82%), Gaps = 3/384 (0%)
Query: 17 SVDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVE 76
SVDL D SLQ++I DA+SERDKVKFTV TK+ LP F EFSV RQHE+F+WLHD +E
Sbjct: 22 SVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIE 81
Query: 77 NEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVA 136
+YAGLIIPPAP +PDF+ REK+QKLGEG+ S+T+EEFAKMKQELEAEYLA+FKKTV+
Sbjct: 82 TTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVS 141
Query: 137 MHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITG 196
HEVFLQRL++HP L +D NF VFLEY QDLSVR KN KE+ GGF +++VKSADE L T
Sbjct: 142 SHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFT- 200
Query: 197 MSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQE 256
G+KEVDDFFE E+ FL+ Y+ RI+D+C++AD++ R+HK +ADDYI +A L SL +E
Sbjct: 201 --GVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEE 258
Query: 257 VNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALAD 316
++ LK+AELFE+LRK+EGRV+SDEDLKL+++LRYYM + +AAKDLLYRR +AL D
Sbjct: 259 PTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALID 318
Query: 317 YENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIE 376
YEN+NKALDKAR ++++V+ AE+HQQ CCQ+FE+LS+SAK+EL++FK +RV++FRKNLIE
Sbjct: 319 YENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIE 378
Query: 377 LAELELKHAKASTLILRNTLVALK 400
++ELE+KHA+ + +L++ + K
Sbjct: 379 MSELEIKHARNNVSLLQSCIDLFK 402
>gi|7657599 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 505 bits (1301), Expect = e-143
Identities = 243/384 (63%), Positives = 317/384 (82%), Gaps = 3/384 (0%)
Query: 17 SVDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVE 76
SVDL D SLQ++I DA+SERDKVKFTV TK+ LP F EFSV RQHE+F+WLHD +E
Sbjct: 22 SVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIE 81
Query: 77 NEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVA 136
+YAGLIIPPAP +PDF+ REK+QKLGEG+ S+T+EEFAKMKQELEAEYLA+FKKTV+
Sbjct: 82 TTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVS 141
Query: 137 MHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITG 196
HEVFLQRL++HP L +D NF VFLEY QDLSVR KN KE+ GGF +++VKSADE L T
Sbjct: 142 SHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFT- 200
Query: 197 MSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQE 256
G+KEVDDFFE E+ FL+ Y+ RI+D+C++AD++ R+HK +ADDYI +A L SL +E
Sbjct: 201 --GVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEE 258
Query: 257 VNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALAD 316
++ LK+AELFE+LRK+EGRV+SDEDLKL+++LRYYM + +AAKDLLYRR +AL D
Sbjct: 259 PTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALID 318
Query: 317 YENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIE 376
YEN+NKALDKAR ++++V+ AE+HQQ CCQ+FE+LS+SAK+EL++FK +RV++FRKNLIE
Sbjct: 319 YENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIE 378
Query: 377 LAELELKHAKASTLILRNTLVALK 400
++ELE+KHA+ + +L++ + K
Sbjct: 379 MSELEIKHARNNVSLLQSCIDLFK 402
>gi|88703043 sorting nexin 6 isoform a [Homo sapiens]
Length = 290
Score = 398 bits (1023), Expect = e-111
Identities = 196/292 (67%), Positives = 246/292 (84%), Gaps = 3/292 (1%)
Query: 111 VTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVR 170
+T+EEF KMKQELEAEYLAIFKKTVAMHEVFL R+AAHP LRRD NF VFLEY QDLSVR
Sbjct: 1 MTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVR 60
Query: 171 GKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADR 230
GKN+KE L F +N+VKSAD ++ SG+K+VDDFFEHERTFLLEYH R++DA ++DR
Sbjct: 61 GKNKKEKLEDFFKNMVKSADGVIV---SGVKDVDDFFEHERTFLLEYHNRVKDASAKSDR 117
Query: 231 VMRAHKCLADDYIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLS 290
+ R+HK ADDY I ++L +LGTQ+ + FLK++ELF++ RK+E RV++DEDLKLS
Sbjct: 118 MTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLS 177
Query: 291 DMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESHQQLCCQRFER 350
D+L+YY+R+SQAAKDLLYRR R+L DYENANKALDKAR +N++V AE+ QQLCCQ+FE+
Sbjct: 178 DLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEK 237
Query: 351 LSDSAKQELMDFKSRRVSSFRKNLIELAELELKHAKASTLILRNTLVALKGE 402
+S+SAKQEL+DFK+RRV++FRKNL+ELAELELKHAK + +L+N L L G+
Sbjct: 238 ISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGD 289
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 100 bits (249), Expect = 2e-21
Identities = 95/376 (25%), Positives = 170/376 (45%), Gaps = 46/376 (12%)
Query: 29 EISDAVSERDKV--------KFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEY 80
+I VS+ +KV + V TK+ L F+++EFSV R+ +F+ LH +
Sbjct: 141 DIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLH 200
Query: 81 AGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEV 140
G I+PPAP + ++ K+G+ DSS T EF + ++ A E
Sbjct: 201 VGYIVPPAPEKSIVGMTK---VKVGKEDSSST--EFVEKRR--------------AALER 241
Query: 141 FLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGL 200
+LQR HPTL +D + FLE + R N + L G + +V A +A+ +
Sbjct: 242 YLQRTVKHPTLLQDPDLRQFLESSE--LPRAVNTQALSGAGILRMVNKAADAVNKMTIKM 299
Query: 201 KEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEVN-Q 259
E D +FE ++ ++R + + ++ K L+ + + + + LG E +
Sbjct: 300 NESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTA 359
Query: 260 LRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYEN 319
L + +LAE+ E++ +L A + S++L Y+R A K + R++ +E+
Sbjct: 360 LSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWED 419
Query: 320 ANKAL----------------DKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFK 363
A L DK + E+R E+ Q + FE++S + ++E+ F+
Sbjct: 420 AQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFE 479
Query: 364 SRRVSSFRKNLIELAE 379
RV F+ +I+ E
Sbjct: 480 KERVKDFKTVIIKYLE 495
>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
Length = 457
Score = 91.7 bits (226), Expect = 1e-18
Identities = 86/357 (24%), Positives = 162/357 (45%), Gaps = 38/357 (10%)
Query: 40 VKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASRE 99
V + V T++ LP F +F+V R+ +F+ L++ E G I+PP P + ++
Sbjct: 98 VAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTK- 156
Query: 100 KLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFV 159
K+G+ DSS AE+L +K A E +LQR+ HPT+ +D +
Sbjct: 157 --VKVGKEDSS-------------SAEFL---EKRRAALERYLQRIVNHPTMLQDPDVRE 198
Query: 160 FLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHT 219
FLE ++ R + L G L + A +A+ + E D +FE + +
Sbjct: 199 FLE--KEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQ 256
Query: 220 RIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEVN-QLRTSFLKLAELFERLRKLE 278
R+R + ++ K LA + + +L+ LG+ E N L + +LAE+ E++ +L
Sbjct: 257 RLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLH 316
Query: 279 GRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKAL-------------- 324
A+++ L+++L Y+R + +R++ +++A L
Sbjct: 317 QEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWAN 376
Query: 325 --DKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAE 379
DK + E+ ES + FER+S ++E++ F+ + F+ ++I+ E
Sbjct: 377 KPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLE 433
>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
Length = 522
Score = 91.7 bits (226), Expect = 1e-18
Identities = 86/357 (24%), Positives = 162/357 (45%), Gaps = 38/357 (10%)
Query: 40 VKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASRE 99
V + V T++ LP F +F+V R+ +F+ L++ E G I+PP P + ++
Sbjct: 163 VAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTK- 221
Query: 100 KLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFV 159
K+G+ DSS AE+L +K A E +LQR+ HPT+ +D +
Sbjct: 222 --VKVGKEDSS-------------SAEFL---EKRRAALERYLQRIVNHPTMLQDPDVRE 263
Query: 160 FLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHT 219
FLE ++ R + L G L + A +A+ + E D +FE + +
Sbjct: 264 FLE--KEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQ 321
Query: 220 RIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEVN-QLRTSFLKLAELFERLRKLE 278
R+R + ++ K LA + + +L+ LG+ E N L + +LAE+ E++ +L
Sbjct: 322 RLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLH 381
Query: 279 GRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKAL-------------- 324
A+++ L+++L Y+R + +R++ +++A L
Sbjct: 382 QEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWAN 441
Query: 325 --DKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAE 379
DK + E+ ES + FER+S ++E++ F+ + F+ ++I+ E
Sbjct: 442 KPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLE 498
>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
Length = 474
Score = 80.5 bits (197), Expect = 3e-15
Identities = 83/341 (24%), Positives = 153/341 (44%), Gaps = 54/341 (15%)
Query: 40 VKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASRE 99
V + V T++ LP F +F+V R+ +F+ L++ E G I+PP P + ++
Sbjct: 163 VAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTK- 221
Query: 100 KLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFV 159
K+G+ DSS AE+L +K A E +LQR+ HPT+ +D +
Sbjct: 222 --VKVGKEDSS-------------SAEFL---EKRRAALERYLQRIVNHPTMLQDPDVRE 263
Query: 160 FLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHT 219
FLE ++ R + L G L + A +A+ + E D +FE + +
Sbjct: 264 FLE--KEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQ 321
Query: 220 RIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEVN-QLRTSFLKLAELFERLRKLE 278
R+R + ++ K LA + + +L+ LG+ E N L + +LAE+ E++ +L
Sbjct: 322 RLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLH 381
Query: 279 GRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNREVRPAE 338
A+++ L+++L Y+ RL A+ +E +R E
Sbjct: 382 QEQANNDFFLLAELLSDYI------------RLLAIVRWE--------SRVTQYE----- 416
Query: 339 SHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAE 379
+ FER+S ++E++ F+ + F+ ++I+ E
Sbjct: 417 -------RDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLE 450
>gi|153791707 sorting nexin family member 30 [Homo sapiens]
Length = 437
Score = 53.1 bits (126), Expect = 4e-07
Identities = 82/351 (23%), Positives = 153/351 (43%), Gaps = 50/351 (14%)
Query: 40 VKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASRE 99
+ + + TKS F E+SV R++++F WL E++ +IPP P E
Sbjct: 109 ITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTH--LIPPLP---------E 157
Query: 100 KLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFV 159
K G D EEF + +++ A+ K FL+R+ HP L + +F +
Sbjct: 158 KFVVKGVVDR--FSEEFVETRRK------ALDK--------FLKRITDHPVLSFNEHFNI 201
Query: 160 FLEYGQDLSVRGKNRKELL---GGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLE 216
FL +DL+ K LL G ++++ + L T + D+ + TF L+
Sbjct: 202 FLT-AKDLNAYKKQGIALLTRMGESVKHV--TGGYKLRTRPLEFAAIGDYLD---TFALK 255
Query: 217 YHTRIRDACLRADRVMRAH-KCLAD--DYIPISAALSSLGTQEVNQLRTSFLKLAELFER 273
T R A R+++ + L + +Y P+ + S+L + L +
Sbjct: 256 LGTIDR----IAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTA 311
Query: 274 LRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKALDKARTRNRE 333
L +L + D +LR Y+ S + K +L +R + A+YE +A+ R +R
Sbjct: 312 LEELTDDMTED----FLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAV-ALRKEDRP 366
Query: 334 VRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELKH 384
PA+ + C R E + K ++ +++ + FR+ L+ +A+ +++
Sbjct: 367 KVPADVEK--CQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQY 415
>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
Length = 336
Score = 50.1 bits (118), Expect = 4e-06
Identities = 63/289 (21%), Positives = 121/289 (41%), Gaps = 40/289 (13%)
Query: 40 VKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASRE 99
+ + + TK+ F +EF V R++++F+WL E + LIIPP P + + E
Sbjct: 50 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKL--EEAHPTLIIPPLPEKFIVKGMVE 107
Query: 100 KLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFV 159
+ ++F + +++ A+H+ FL R+A HPTL + +F +
Sbjct: 108 RF-----------NDDFIETRRK-------------ALHK-FLNRIADHPTLTFNEDFKI 142
Query: 160 FL-EYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYH 218
FL +LS K LL + + A+ + M G+K + F F+ +
Sbjct: 143 FLTAQAWELSSHKKQGPGLLSRMGQTV-----RAVASSMRGVKNRPEEFMEMNNFIELFS 197
Query: 219 TRIRDACLRADRVMRAHKCLAD---DYIPISAALSSLGTQEVNQLRTSFLKLAELFERLR 275
+I + R+ + + D +Y PI S+ V+ L+ +A +R
Sbjct: 198 QKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLK----DVASCIDRCC 253
Query: 276 KLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKAL 324
K + S L ++ Y+ S+ ++ RR + A+ ++ + L
Sbjct: 254 KATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVL 302
>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
Length = 451
Score = 50.1 bits (118), Expect = 4e-06
Identities = 63/289 (21%), Positives = 121/289 (41%), Gaps = 40/289 (13%)
Query: 40 VKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASRE 99
+ + + TK+ F +EF V R++++F+WL E + LIIPP P + + E
Sbjct: 114 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKL--EEAHPTLIIPPLPEKFIVKGMVE 171
Query: 100 KLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFV 159
+ ++F + +++ A+H+ FL R+A HPTL + +F +
Sbjct: 172 RF-----------NDDFIETRRK-------------ALHK-FLNRIADHPTLTFNEDFKI 206
Query: 160 FL-EYGQDLSVRGKNRKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYH 218
FL +LS K LL + + A+ + M G+K + F F+ +
Sbjct: 207 FLTAQAWELSSHKKQGPGLLSRMGQTV-----RAVASSMRGVKNRPEEFMEMNNFIELFS 261
Query: 219 TRIRDACLRADRVMRAHKCLAD---DYIPISAALSSLGTQEVNQLRTSFLKLAELFERLR 275
+I + R+ + + D +Y PI S+ V+ L+ +A +R
Sbjct: 262 QKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVDTLK----DVASCIDRCC 317
Query: 276 KLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYENANKAL 324
K + S L ++ Y+ S+ ++ RR + A+ ++ + L
Sbjct: 318 KATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVL 366
>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
Length = 855
Score = 37.0 bits (84), Expect = 0.032
Identities = 63/284 (22%), Positives = 120/284 (42%), Gaps = 45/284 (15%)
Query: 76 ENEEYAGLIIPPAPP--RPDF--------EASREKLQKLGEGDSSVTREEFAKMK-QELE 124
E EEYA L++ P R + E +REK+Q G + + + K++ +ELE
Sbjct: 6 EEEEYARLVMEAQPEWLRAEVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELE 65
Query: 125 AEYLAIFKKTVAMHEVFLQRLAAHPTL-----RRDHNFFVFLEYGQDLSVRGKNRKELLG 179
+Y AI + + E F Q H + R+ + + VR +
Sbjct: 66 VDYEAIRSEMEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTEL 125
Query: 180 GFLRNIV---KSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHK 236
LRN++ +S +E L + LKE++ E +R L + I++ R R+++ +
Sbjct: 126 KQLRNVLTNTQSENERLASVAQELKEINQNVEIQRGRLRD---DIKEYKFREARLLQDYS 182
Query: 237 CLADDYIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYY 296
L ++ I + ++V+ LR + ++ L +++LE + ++ L
Sbjct: 183 ELEEENISLQ--------KQVSVLRQNQVEFEGLKHEIKRLE---------EETEYLNSQ 225
Query: 297 MRDSQAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESH 340
+ D+ K++ R+L E A + L R + +R SH
Sbjct: 226 LEDAIRLKEISERQL------EEALETLKTEREQKNSLRKELSH 263
Score = 32.3 bits (72), Expect = 0.78
Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 27/164 (16%)
Query: 182 LRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADD 241
LR ++K+ + ++ LK +E+E+ + E ++R+ K L +D
Sbjct: 693 LRTVLKANKQTAEVALANLKSK---YENEKAMVTETMMKLRNEL----------KALKED 739
Query: 242 YIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQ 301
+A SSL + +L E+ +L A DE L+ +LR ++
Sbjct: 740 ----AATFSSLRAMFATRCDEYITQLDEMQRQLA-----AAEDEKKTLNSLLRMAIQQKL 790
Query: 302 AAKDLLYRRLRALA-DYENANKALDKARTRNREVRPAESHQQLC 344
A L +RL L D+E + KA + + P+ SH C
Sbjct: 791 A----LTQRLELLELDHEQTRRGRAKAAPKTKPATPSVSHTCAC 830
>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
Length = 824
Score = 37.0 bits (84), Expect = 0.032
Identities = 63/284 (22%), Positives = 120/284 (42%), Gaps = 45/284 (15%)
Query: 76 ENEEYAGLIIPPAPP--RPDF--------EASREKLQKLGEGDSSVTREEFAKMK-QELE 124
E EEYA L++ P R + E +REK+Q G + + + K++ +ELE
Sbjct: 6 EEEEYARLVMEAQPEWLRAEVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELE 65
Query: 125 AEYLAIFKKTVAMHEVFLQRLAAHPTL-----RRDHNFFVFLEYGQDLSVRGKNRKELLG 179
+Y AI + + E F Q H + R+ + + VR +
Sbjct: 66 VDYEAIRSEMEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTEL 125
Query: 180 GFLRNIV---KSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHK 236
LRN++ +S +E L + LKE++ E +R L + I++ R R+++ +
Sbjct: 126 KQLRNVLTNTQSENERLASVAQELKEINQNVEIQRGRLRD---DIKEYKFREARLLQDYS 182
Query: 237 CLADDYIPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYY 296
L ++ I + ++V+ LR + ++ L +++LE + ++ L
Sbjct: 183 ELEEENISLQ--------KQVSVLRQNQVEFEGLKHEIKRLE---------EETEYLNSQ 225
Query: 297 MRDSQAAKDLLYRRLRALADYENANKALDKARTRNREVRPAESH 340
+ D+ K++ R+L E A + L R + +R SH
Sbjct: 226 LEDAIRLKEISERQL------EEALETLKTEREQKNSLRKELSH 263
>gi|23111030 sorting nexin 12 [Homo sapiens]
Length = 162
Score = 36.6 bits (83), Expect = 0.041
Identities = 28/121 (23%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 42 FTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASREKL 101
+ V+ ++ LP F E V R++ +F WL + E E + +++PP P + K
Sbjct: 50 YEVRMRTNLPIFKLKESCVRRRYSDFEWLKN---ELERDSKIVVPPLPGKA------LKR 100
Query: 102 QKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVFL 161
Q GD + E F + +++ E F+ ++A HP + + +FL
Sbjct: 101 QLPFRGDEGIFEESFIEERRQ--------------GLEQFINKIAGHPLAQNERCLHMFL 146
Query: 162 E 162
+
Sbjct: 147 Q 147
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 35.8 bits (81), Expect = 0.071
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)
Query: 296 YMRDSQAAKDLLYRRLRALADYENANKALDKARTRNRE----VRPAESHQQLCCQRFERL 351
Y+ K+ + +R R L DY++A L+ ++ R+ + AE Q + FE
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
Query: 352 SDSAKQELMDFKSRRVSSFRKNLIELAELELKHAK 386
+ ++EL SRRV + ++ LE K K
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHK 218
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 35.8 bits (81), Expect = 0.071
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 4/95 (4%)
Query: 296 YMRDSQAAKDLLYRRLRALADYENANKALDKARTRNRE----VRPAESHQQLCCQRFERL 351
Y+ K+ + +R R L DY++A L+ ++ R+ + AE Q + FE
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
Query: 352 SDSAKQELMDFKSRRVSSFRKNLIELAELELKHAK 386
+ ++EL SRRV + ++ LE K K
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHK 218
>gi|4507143 sorting nexin 3 isoform a [Homo sapiens]
Length = 162
Score = 35.8 bits (81), Expect = 0.071
Identities = 29/122 (23%), Positives = 52/122 (42%), Gaps = 25/122 (20%)
Query: 42 FTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAPPRPDFEASREKL 101
+ ++ K+ LP F E +V R++ +F WL E E + +++PP P +
Sbjct: 49 YEIRVKTNLPIFKLKESTVRRRYSDFEWLRS---ELERESKVVVPPLPGKAFLR------ 99
Query: 102 QKLGEGDSSVTREEFAK-MKQELEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVF 160
Q GD + + F + KQ LE F+ ++A HP + + +F
Sbjct: 100 QLPFRGDDGIFDDNFIEERKQGLEQ---------------FINKVAGHPLAQNERCLHMF 144
Query: 161 LE 162
L+
Sbjct: 145 LQ 146
>gi|117553613 coiled-coil domain containing 151 [Homo sapiens]
Length = 595
Score = 35.4 bits (80), Expect = 0.092
Identities = 51/245 (20%), Positives = 96/245 (39%), Gaps = 21/245 (8%)
Query: 123 LEAEYLAIFKKTVAMHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFL 182
+EAE + + A+H V + L A + L+Y ++ VR + ++E ++
Sbjct: 251 MEAEVVRTKHELEALHVVNQEALNARDIAKNQ------LQYLEETLVRERKKRER---YI 301
Query: 183 RNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDY 242
K A+E + ++ H LL+ I+D+ + +R +
Sbjct: 302 SECKKRAEEKKLENERMERKT-----HREHLLLQSDDTIQDSLHAKEEELRQRWSMYQME 356
Query: 243 IPISAALSSLGTQEVNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQA 302
+ + GT E + L FL + F +L L+ S+ + L + + + +
Sbjct: 357 VIFGKVKDATGTDETHSLVRRFLAQGDTFAQLETLK----SENEQTLVRLKQEKQQLQRE 412
Query: 303 AKDLLYRRLRALADYENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDF 362
+DL Y L + +A + R + E R AE+ QL +R R AK L
Sbjct: 413 LEDLKYSGEATLVSQQKL-QAEAQERLKKEERRHAEAKDQL--ERALRAMQVAKDSLEHL 469
Query: 363 KSRRV 367
S+ +
Sbjct: 470 ASKLI 474
>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
sapiens]
Length = 805
Score = 34.7 bits (78), Expect = 0.16
Identities = 43/183 (23%), Positives = 77/183 (42%), Gaps = 32/183 (17%)
Query: 200 LKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQ-EVN 258
L++ + + ++ + H RIRD LRA M H +D + ++SL Q E
Sbjct: 371 LRQKEIVIDRQKQQITHLHERIRDNELRAQHAMLGHYVNCED-----SYVASLQPQYENT 425
Query: 259 QLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADYE 318
L+T F + + + + E ++AS E ++ + L +RL + E
Sbjct: 426 SLQTPFSEESVSHSQQGEFEQKLASTE------------KEVLQLNEFLKQRLSLFS--E 471
Query: 319 NANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELA 378
K +K +TR+R + S + CQ+ + E K RR+ + K L +L
Sbjct: 472 EKKKLEEKLKTRDRYI----SSLKKKCQK--------ESEQNKEKQRRIETLEKYLADLP 519
Query: 379 ELE 381
L+
Sbjct: 520 TLD 522
>gi|51093830 bicaudal D homolog 1 isoform 2 [Homo sapiens]
Length = 835
Score = 33.1 bits (74), Expect = 0.46
Identities = 58/249 (23%), Positives = 102/249 (40%), Gaps = 41/249 (16%)
Query: 95 EASREKLQKLGEGDSSVTREEFAKMKQ---ELEAEYLAIFKKTVAMHEVFLQRLAAHPTL 151
E + EK+Q G V EE +KQ ELEAEY ++ ++ + E F Q + H +
Sbjct: 26 ETTHEKIQAAEYG--LVVLEEKLTLKQQYDELEAEYDSLKQELEQLKEAFGQSFSIHRKV 83
Query: 152 RRDHNFFVFLEYGQDLSVRGKNRKE--LLGGFLR------------NIVKSADEALITGM 197
D E ++ ++ KE LG L V++ +E L +
Sbjct: 84 AEDG------ETREETLLQESASKEAYYLGKILEMQNELKQSRAVVTNVQAENERLTAVV 137
Query: 198 SGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEV 257
LKE ++ E +R + IR+ R R+++ + L ++ I + +S+L +
Sbjct: 138 QDLKENNEMVELQR---IRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTL---KQ 191
Query: 258 NQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADY 317
NQ+ LK +++ E +E + L+ L +R + A+ L L L +
Sbjct: 192 NQVEYEGLK-----HEIKRFE-----EETVLLNSQLEDAIRLKEIAEHQLEEALETLKNE 241
Query: 318 ENANKALDK 326
L K
Sbjct: 242 REQKNNLRK 250
>gi|51039802 bicaudal D homolog 1 isoform 1 [Homo sapiens]
Length = 975
Score = 33.1 bits (74), Expect = 0.46
Identities = 58/249 (23%), Positives = 102/249 (40%), Gaps = 41/249 (16%)
Query: 95 EASREKLQKLGEGDSSVTREEFAKMKQ---ELEAEYLAIFKKTVAMHEVFLQRLAAHPTL 151
E + EK+Q G V EE +KQ ELEAEY ++ ++ + E F Q + H +
Sbjct: 26 ETTHEKIQAAEYG--LVVLEEKLTLKQQYDELEAEYDSLKQELEQLKEAFGQSFSIHRKV 83
Query: 152 RRDHNFFVFLEYGQDLSVRGKNRKE--LLGGFLR------------NIVKSADEALITGM 197
D E ++ ++ KE LG L V++ +E L +
Sbjct: 84 AEDG------ETREETLLQESASKEAYYLGKILEMQNELKQSRAVVTNVQAENERLTAVV 137
Query: 198 SGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQEV 257
LKE ++ E +R + IR+ R R+++ + L ++ I + +S+L +
Sbjct: 138 QDLKENNEMVELQR---IRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTL---KQ 191
Query: 258 NQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALADY 317
NQ+ LK +++ E +E + L+ L +R + A+ L L L +
Sbjct: 192 NQVEYEGLK-----HEIKRFE-----EETVLLNSQLEDAIRLKEIAEHQLEEALETLKNE 241
Query: 318 ENANKALDK 326
L K
Sbjct: 242 REQKNNLRK 250
>gi|110735404 protein tyrosine phosphatase, receptor type, U isoform 1
precursor [Homo sapiens]
Length = 1436
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/88 (22%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 30 ISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAP 89
+ D + + + + V +C+ ++++ E++I++HDA +E A L
Sbjct: 1087 VLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE----ACLCGETTI 1142
Query: 90 PRPDFEASREKLQKLG-EGDSSVTREEF 116
P +F+A+ +++ ++ + +SS REEF
Sbjct: 1143 PVSEFKATYKEMIRIDPQSNSSQLREEF 1170
>gi|110735406 protein tyrosine phosphatase, receptor type, U isoform 2
precursor [Homo sapiens]
Length = 1442
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/88 (22%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 30 ISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAP 89
+ D + + + + V +C+ ++++ E++I++HDA +E A L
Sbjct: 1093 VLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE----ACLCGETTI 1148
Query: 90 PRPDFEASREKLQKLG-EGDSSVTREEF 116
P +F+A+ +++ ++ + +SS REEF
Sbjct: 1149 PVSEFKATYKEMIRIDPQSNSSQLREEF 1176
>gi|110735402 protein tyrosine phosphatase, receptor type, U isoform 3
precursor [Homo sapiens]
Length = 1446
Score = 32.0 bits (71), Expect = 1.0
Identities = 20/88 (22%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 30 ISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVENEEYAGLIIPPAP 89
+ D + + + + V +C+ ++++ E++I++HDA +E A L
Sbjct: 1097 VLDVMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEEQYIFIHDAILE----ACLCGETTI 1152
Query: 90 PRPDFEASREKLQKLG-EGDSSVTREEF 116
P +F+A+ +++ ++ + +SS REEF
Sbjct: 1153 PVSEFKATYKEMIRIDPQSNSSQLREEF 1180
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 32.0 bits (71), Expect = 1.0
Identities = 30/113 (26%), Positives = 54/113 (47%), Gaps = 11/113 (9%)
Query: 273 RLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKD--LLYRRLRALADYENANKALDKARTR 330
R + +EG + SDE +L+ R AA++ +L ++ RA YE K +++ +
Sbjct: 41 RPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYE---KQMEERWRK 97
Query: 331 NREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIELAELELK 383
E R E Q+ + + KQ+L + + R + R++L +LELK
Sbjct: 98 LEEQRQRED------QKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELK 144
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 31.6 bits (70), Expect = 1.3
Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 26/149 (17%)
Query: 255 QEVNQLRTSFL-KLAELFERLRKLEGRVASDEDLKLS---DMLRYYMRDSQAAKDLLYRR 310
QEV QLR+ K EL L++LE L+ + LR+ R+SQ+AK L
Sbjct: 2632 QEVLQLRSMLSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKAL---- 2687
Query: 311 LRALADYENANKALDKARTRNREVRPAESHQQLC---CQRFERLSDSAKQELMDFKSRRV 367
E +L+ R ++ + A H+Q Q+ R+ S + L+ + ++
Sbjct: 2688 -------EELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQL 2740
Query: 368 SSFRKNL-------IELAELELKHAKAST 389
S +K+L +EL+E L+H + T
Sbjct: 2741 SELQKDLAAEKSRTLELSE-ALRHERLLT 2768
>gi|224586875 coiled-coil domain containing 65 [Homo sapiens]
Length = 484
Score = 31.6 bits (70), Expect = 1.3
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 11/84 (13%)
Query: 319 NANKALDKARTRNREVRPAESHQ--QLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIE 376
N NK + RT REV+ E H+ ++ Q FER ++D K + S K+L E
Sbjct: 57 NLNKINTQWRTVLREVKTRELHKDIEILSQTFER--------VVDCKDNVIKSLAKDLSE 108
Query: 377 LAELELKHAKASTLILRNTLVALK 400
AE + HA S L + L+AL+
Sbjct: 109 -AEEQYAHALRSHLHNVDQLLALQ 131
>gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo
sapiens]
Length = 941
Score = 31.2 bits (69), Expect = 1.7
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 307 LYRRLRALADYENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRR 366
L+ L L YENA K L+KA RE P + H + + E + + Q + R
Sbjct: 436 LWLALARLETYENARKVLNKA----RENIPTDRHIWITAAKLEEANGNT-QMVEKIIDRA 490
Query: 367 VSSFRKNLIEL 377
++S R N +E+
Sbjct: 491 ITSLRANGVEI 501
>gi|57863310 stromal antigen 3 [Homo sapiens]
Length = 1225
Score = 31.2 bits (69), Expect = 1.7
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 14/104 (13%)
Query: 174 RKELLGGFLRNIVKSADEALITGMSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMR 233
R+ LL GF + L+ G+ + D F+H F +Y I++ RA ++ R
Sbjct: 870 RRRLLAGFCK--------LLLYGVLEMDAASDVFKHYNKFYNDYGDIIKETLTRARQIDR 921
Query: 234 AHKCLADDYIPISAALSSL----GTQEVNQLRTSFLKLAELFER 273
+H C + + + L G Q +N+L +F+++ +L R
Sbjct: 922 SH-CSRILLLSLKQLYTELLQEHGPQGLNEL-PAFIEMRDLARR 963
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,309,523
Number of Sequences: 37866
Number of extensions: 537899
Number of successful extensions: 2084
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 2041
Number of HSP's gapped (non-prelim): 86
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.