Guide to the Human Genome
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Search of human proteins with 71274178

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71274178 developing brain homeobox 1 [Homo sapiens]
         (382 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71274178 developing brain homeobox 1 [Homo sapiens]                778   0.0  
gi|116174748 developing brain homeobox 2 [Homo sapiens]               127   1e-29
gi|11386181 H2.0-like homeobox [Homo sapiens]                          87   3e-17
gi|153218470 BarH-like homeobox 1 [Homo sapiens]                       80   4e-15
gi|6633798 BarH-like homeobox 2 [Homo sapiens]                         63   4e-10
gi|4885185 distal-less homeobox 3 [Homo sapiens]                       60   3e-09
gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]                  59   7e-09
gi|4885187 distal-less homeobox 5 [Homo sapiens]                       59   1e-08
gi|89257348 homeo box HB9 [Homo sapiens]                               57   4e-08
gi|4504465 homeobox B2 [Homo sapiens]                                  56   5e-08
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...    56   6e-08
gi|147901462 brain specific homeobox [Homo sapiens]                    56   6e-08
gi|4506049 hematopoietically expressed homeobox [Homo sapiens]         55   8e-08
gi|24497513 homeobox A3 isoform a [Homo sapiens]                       52   9e-07
gi|13562112 homeobox A3 isoform a [Homo sapiens]                       52   9e-07
gi|39930383 BarH-like homeobox 2 [Homo sapiens]                        52   9e-07
gi|13273317 homeobox B8 [Homo sapiens]                                 52   1e-06
gi|14149728 BarH-like homeobox 1 [Homo sapiens]                        50   3e-06
gi|4758168 distal-less homeobox 2 [Homo sapiens]                       50   3e-06
gi|28912912 NK6 transcription factor related, locus 2 [Homo sapi...    50   3e-06
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap...    49   8e-06
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]                   48   2e-05
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap...    47   2e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   3e-05
gi|157426823 NK2 homeobox 4 [Homo sapiens]                             46   5e-05
gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]            46   6e-05
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]    46   6e-05
gi|118766339 thyroid transcription factor 1 isoform 1 [Homo sapi...    45   1e-04
gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]     45   1e-04
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     45   1e-04

>gi|71274178 developing brain homeobox 1 [Homo sapiens]
          Length = 382

 Score =  778 bits (2008), Expect = 0.0
 Identities = 382/382 (100%), Positives = 382/382 (100%)

Query: 1   MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPT 60
           MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPT
Sbjct: 1   MMFPGLLAPPAGYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPT 60

Query: 61  ASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGP 120
           ASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGP
Sbjct: 61  ASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGP 120

Query: 121 RTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRR 180
           RTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRR
Sbjct: 121 RTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRR 180

Query: 181 GMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRP 240
           GMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRP
Sbjct: 181 GMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRP 240

Query: 241 RASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNP 300
           RASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNP
Sbjct: 241 RASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNP 300

Query: 301 HPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSPGK 360
           HPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSPGK
Sbjct: 301 HPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSPGK 360

Query: 361 PSDFSDSEEEEEGEEQEEITVS 382
           PSDFSDSEEEEEGEEQEEITVS
Sbjct: 361 PSDFSDSEEEEEGEEQEEITVS 382


>gi|116174748 developing brain homeobox 2 [Homo sapiens]
          Length = 339

 Score =  127 bits (320), Expect = 1e-29
 Identities = 122/361 (33%), Positives = 156/361 (43%), Gaps = 77/361 (21%)

Query: 2   MFPGLLAPPAG-YPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPT 60
           M P  +A  AG Y  ++  +  L LP +      G  SFL+E+L+R+   P   PR  P 
Sbjct: 1   MLPSAVAAHAGAYWDVVASSALLNLPAAPGFGNLG-KSFLIENLLRVGGAPT--PRLQPP 57

Query: 61  ASMSP------------PRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFL 108
           A   P            P   +P  L    A++  SP              SP++++  L
Sbjct: 58  APHDPATALATAGAQLRPLPASPVPLKLCPAAEQVSPAGAPYGTRWAFQVLSPSADSARL 117

Query: 109 KFGV----NAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPI 164
                   +          + P LL S PP  F      GS +    S+ FP   S++P+
Sbjct: 118 PGRAPGDRDCTFQPSAPAPSKPFLL-STPP--FYSACCGGSCRRPASSTAFPREESMLPL 174

Query: 165 PGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQ 224
               S       K RRG+LRRAVFS+ QRKALEKMFQKQKYISK DRKKLA  LGLK+S 
Sbjct: 175 LTQDS-----NSKARRGILRRAVFSEDQRKALEKMFQKQKYISKTDRKKLAINLGLKES- 228

Query: 225 DTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELL 284
                                                 QVKIWFQNRRMKWRNSKE+E+L
Sbjct: 229 --------------------------------------QVKIWFQNRRMKWRNSKEKEVL 250

Query: 285 SSG-----GCREQTLPTKL----NPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSD 335
           S+      G +E  L        +P P + DV Q+       E  P  PS RL   +S  
Sbjct: 251 SNRCIQEVGLQEDPLSRSALGFPSPCPSIWDVPQQHSSPRWRENSP-EPSERLIQESSGA 309

Query: 336 P 336
           P
Sbjct: 310 P 310


>gi|11386181 H2.0-like homeobox [Homo sapiens]
          Length = 488

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 100/346 (28%), Positives = 129/346 (37%), Gaps = 84/346 (24%)

Query: 15  SLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPTASMSPP--RQGAPT 72
           S LRPTP +  P  + + F    S L         P     +  P     PP  R GA  
Sbjct: 91  SPLRPTPVVA-PSEVPAGFPQRLSPL-SAAYHHHHPQQQQQQQQPQQQQPPPPPRAGA-- 146

Query: 73  ALTDTGASDLGSPGPGSRRGGSPPTAFS-PASETTFLKFGVNAILSS--GPRTETSPALL 129
                    L  P  G+R   +P  + S PA  +  LKFG++ ILS+   P+ +    L 
Sbjct: 147 ---------LQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLR 197

Query: 130 QSVPPKTFAFP-------------YFEGSFQPFIRSSYF-------PASSSVVPIPGTFS 169
                 T   P              F  S  P   +S         P +S       TF 
Sbjct: 198 DLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNPRNSVQHQFQDTFP 257

Query: 170 WPLAARGKP-------RRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKD 222
            P A   K        R+    RAVFS++QRK LEK F+ QKY++KPDRK+LAA LGL D
Sbjct: 258 GPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTD 317

Query: 223 SQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERE 282
           +                                       QVK+WFQNRRMKWR+SKE +
Sbjct: 318 A---------------------------------------QVKVWFQNRRMKWRHSKEAQ 338

Query: 283 LLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRL 328
                       P+   P  D     +    +E E E   S S  L
Sbjct: 339 AQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESL 384


>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
          Length = 254

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 80/266 (30%), Positives = 108/266 (40%), Gaps = 77/266 (28%)

Query: 85  PGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEG 144
           PGP   +G +P  A + A E   LKFGV A+L++ P   +  A+L++     F FP    
Sbjct: 39  PGP---KGAAPAAAAAAAGE--LLKFGVQALLAARP-FHSHLAVLKAEQAAVFKFP---- 88

Query: 145 SFQPFIRSSYFPASSSVVP-IPGTFSWP-----LAARGK------------PRRGMLRRA 186
              P   S    A  +  P +PG    P     L  RGK             ++G   R 
Sbjct: 89  -LAPLGCSGLSSALLAAGPGLPGAAGAPHLPLELQLRGKLEAAGPGEPGTKAKKGRRSRT 147

Query: 187 VFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRPRASPGA 246
           VF+++Q   LEK F+KQKY+S PDR  LA  LGL                          
Sbjct: 148 VFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQ------------------------ 183

Query: 247 PDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQTLP---TKLNPHPD 303
                           QVK W+QNRRMKW+    + +L  GG    T P    K N  P 
Sbjct: 184 ---------------LQVKTWYQNRRMKWK----KIVLQGGGLESPTKPKGRPKKNSIPT 224

Query: 304 LSDVGQKGPGNEEEE--EGPGSPSHR 327
              + ++    + E+  E PG PS R
Sbjct: 225 SEQLTEQERAKDAEKPAEVPGEPSDR 250


>gi|6633798 BarH-like homeobox 2 [Homo sapiens]
          Length = 279

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 55/212 (25%), Positives = 76/212 (35%), Gaps = 48/212 (22%)

Query: 152 SSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDR 211
           S+  P   ++         P   + KPRR    R +F+++Q   LEK FQKQKY+S PDR
Sbjct: 107 SAEAPGGEALASSESETEQPTPRQKKPRRS---RTIFTELQLMGLEKKFQKQKYLSTPDR 163

Query: 212 KKLAAKLGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNR 271
             LA  LGL                                          QVK W+QNR
Sbjct: 164 LDLAQSLGLTQ---------------------------------------LQVKTWYQNR 184

Query: 272 RMKW-----RNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSH 326
           RMKW     +  +E      G  ++ ++PT      +   +  +  G E+ E   G    
Sbjct: 185 RMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAE-EKMNSQAQGQEQLEPSQGQEEL 243

Query: 327 RLAYHASSDPQHLRDPRLPGPLPPSPAHSSSP 358
             A    +    L     P P    P  SS P
Sbjct: 244 CEAQEPKARDVPLEMAEPPDPPQELPIPSSEP 275


>gi|4885185 distal-less homeobox 3 [Homo sapiens]
          Length = 287

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 58/203 (28%), Positives = 80/203 (39%), Gaps = 63/203 (31%)

Query: 176 GKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPD 235
           GKP++    R ++S  Q  AL++ FQK +Y++ P+R +LAA+LGL  +            
Sbjct: 124 GKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQT------------ 171

Query: 236 STPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRN-SKEREL-LSSGGCREQT 293
                                      QVKIWFQNRR K++   K  E+ L        +
Sbjct: 172 ---------------------------QVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDS 204

Query: 294 LPTKLNPHPDLSDVGQKG-PGNEEEEEGPGSPSHRLAYHASSDPQHLRDP--------RL 344
           +     P P L D      P     +  P  P        S+ P +L DP         L
Sbjct: 205 MACNSPPSPALWDTSSHSTPAPARSQLPPPLP-------YSASPSYLDDPTNSWYHAQNL 257

Query: 345 PGP----LPPSPA--HSSSPGKP 361
            GP     PP PA  H +SPG P
Sbjct: 258 SGPHLQQQPPQPATLHHASPGPP 280


>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
          Length = 291

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 69/248 (27%), Positives = 94/248 (37%), Gaps = 72/248 (29%)

Query: 64  SPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPT--------------AFSPASETTFLK 109
           SP +  AP      GAS LG P PG R G + P+              A S +   +   
Sbjct: 26  SPDQDSAPAPRGPDGASYLGGP-PGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLSLAP 84

Query: 110 FGVNAILSSGPRTETSPALLQSVPPKT-----------FAFPYFEGSFQPFIRSSYFPAS 158
            GV  + +  P     P  L S  P               FP+ E S + F++   F A+
Sbjct: 85  AGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESS-RRFVKDR-FTAA 142

Query: 159 SSVVPIPGT--FSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAA 216
           +++ P   T     P   R  P+R   R + FS VQ   LEK F +QKY++  +R  LA 
Sbjct: 143 AALTPFTVTRRIGHPYQNRTPPKRKKPRTS-FSRVQICELEKRFHRQKYLASAERAALAK 201

Query: 217 KLGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWR 276
            L + D+                                       QVK WFQNRR KWR
Sbjct: 202 SLKMTDA---------------------------------------QVKTWFQNRRTKWR 222

Query: 277 --NSKERE 282
              ++ERE
Sbjct: 223 RQTAEERE 230


>gi|4885187 distal-less homeobox 5 [Homo sapiens]
          Length = 289

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 67/280 (23%), Positives = 114/280 (40%), Gaps = 65/280 (23%)

Query: 60  TASMSPPRQGAPTALTDTGA--SDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILS 117
           +A+M  P Q +PT L ++ A  SD  SP  G+  G   PT+ S        ++  + +  
Sbjct: 24  SAAMHHPSQESPT-LPESSATDSDYYSPTGGAPHGYCSPTSASYGKALNPYQYQYHGVNG 82

Query: 118 SGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRS-SYFPASSSVVPIPGTFSWPLAARG 176
           S            S P K +A   +  S+  +  + +  P++++      T        G
Sbjct: 83  SAG----------SYPAKAYADYSYASSYHQYGGAYNRVPSATNQPEKEVTEPEVRMVNG 132

Query: 177 KPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDS 236
           KP++    R ++S  Q  AL++ FQK +Y++ P+R +LAA LGL  +             
Sbjct: 133 KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQT------------- 179

Query: 237 TPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPT 296
                                     QVKIWFQN+R     SK ++++ +G    +  P+
Sbjct: 180 --------------------------QVKIWFQNKR-----SKIKKIMKNGEMPPEHSPS 208

Query: 297 KLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDP 336
             +P      +    P +    E  GS S  L++H  + P
Sbjct: 209 SSDP------MACNSPQSPAVWEPQGS-SRSLSHHPHAHP 241


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 80/323 (24%), Positives = 116/323 (35%), Gaps = 93/323 (28%)

Query: 70  APTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLK--FGVNAILSSGPRTETSPA 127
           A  A     A+  G    G   GG+   A  PA    +    +G +A  ++       PA
Sbjct: 122 AAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPA 181

Query: 128 LLQSVPPKTFAFPYFE--------GSFQPFIRSSYFPASSSVVPIPGTFSWPLAAR---- 175
           L  S P    A P           G+FQ      +  AS++ + +P    +   A+    
Sbjct: 182 LSYSYPQVQGAHPAHPADPIKLGAGTFQ---LDQWLRASTAGMILPKMPDFNSQAQSNLL 238

Query: 176 GKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPD 235
           GK RR    R  F+  Q   LE  F+  KY+S+P R ++A  L L ++Q           
Sbjct: 239 GKCRRP---RTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQ----------- 284

Query: 236 STPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQTLP 295
                                       VKIWFQNRRMKW+ SK+ +  ++    +Q   
Sbjct: 285 ----------------------------VKIWFQNRRMKWKRSKKAKEQAAQEAEKQK-- 314

Query: 296 TKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHS 355
                       G  G G  EE   PG+                    L G  PP+P   
Sbjct: 315 ---------GGGGGAGKGGAEE---PGA------------------EELLG--PPAPGDK 342

Query: 356 SSPGKPSDFSDSEEEEEGEEQEE 378
            S  +  D  DS+ EE+ +E +E
Sbjct: 343 GSGRRLRDLRDSDPEEDEDEDDE 365


>gi|4504465 homeobox B2 [Homo sapiens]
          Length = 356

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 75/285 (26%), Positives = 100/285 (35%), Gaps = 81/285 (28%)

Query: 101 PASETTFLKFGVNAILSSGPRT----ETSPALLQSVPPKTFAFPYF-EGSFQPFIRSSYF 155
           P  E TF      A     PR+    E  PAL    PP   A P   E  +    +S+  
Sbjct: 47  PPFEQTFPSLQPGASTLQRPRSQKRAEDGPALPPPPPPPLPAAPPAPEFPWMKEKKSAKK 106

Query: 156 PASSSVVPIPGTFSWPLAARGKPRRGM-----------LRRAVFSDVQRKALEKMFQKQK 204
           P+ S+  P P   + P +  G P  G+             R  +++ Q   LEK F   K
Sbjct: 107 PSQSATSPSPAASAVPASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNK 166

Query: 205 YISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQV 264
           Y+ +P R ++AA L L +                                        QV
Sbjct: 167 YLCRPRRVEIAALLDLTER---------------------------------------QV 187

Query: 265 KIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSP 324
           K+WFQNRRMK +   +      G   E   P  L    D+ D        EE    PG P
Sbjct: 188 KVWFQNRRMKHKRQTQHREPPDG---EPACPGALE---DICDPA------EEPAASPGGP 235

Query: 325 S-HRLAYHASSDPQHLRDPRLPGPLPPSP---------AHSSSPG 359
           S  R A+ A   P  +    +PG L   P         A +SSPG
Sbjct: 236 SASRAAWEACCHPPEV----VPGALSADPRPLAVRLEGAGASSPG 276


>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 74/295 (25%), Positives = 110/295 (37%), Gaps = 73/295 (24%)

Query: 4   PGLLAPPA--GYPSLLRPTPTLTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPTA 61
           PG L PPA  G  SL  P      PQ L SA + H    + D++     P     ++P+A
Sbjct: 69  PGGLKPPATGGLSSLGSP------PQQL-SAATPHG---INDILSRPSMPVASGAALPSA 118

Query: 62  SMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPP----------TAFSPASETTFLKFG 111
           S S     + ++ + + AS   +    +    S P          ++ SP      L F 
Sbjct: 119 SPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFS 178

Query: 112 VNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWP 171
            +A   +       P  L  +P +T         F P +  S     + +   P   S  
Sbjct: 179 PSAAAVAAVGRYPKP--LAELPGRT-------PIFWPGVMQSPPWRDARLACTPHQGSIL 229

Query: 172 LAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTE 231
           L   GK +     R  FS  Q  ALEK F++ KY++ P+R +LA  LG+ +S        
Sbjct: 230 LDKDGKRKH---TRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTES-------- 278

Query: 232 PAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSS 286
                                          QVK+WFQNRR KWR     E+ ++
Sbjct: 279 -------------------------------QVKVWFQNRRTKWRKKHAAEMATA 302


>gi|147901462 brain specific homeobox [Homo sapiens]
          Length = 233

 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 45/125 (36%), Positives = 59/125 (47%), Gaps = 20/125 (16%)

Query: 158 SSSVVPIPGTFSWPLAAR--GKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLA 215
           ++S +P+P  F  P  A   GK  R    R VFSD Q   LEK F+ Q+Y+S P+R +LA
Sbjct: 85  TTSGMPVPALFPHPQHAELPGKHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELA 144

Query: 216 AKLGLKDSQDTA---------------RRTEP-APDSTPRPRASP-GAPDLTSASPFFS- 257
             L L ++Q                   + EP APD    P  SP G+   T+A    S 
Sbjct: 145 TALSLSETQVKTWFQNRRMKHKKQLRKSQDEPKAPDGPESPEGSPRGSEAATAAEARLSL 204

Query: 258 PAGTF 262
           PAG F
Sbjct: 205 PAGPF 209


>gi|4506049 hematopoietically expressed homeobox [Homo sapiens]
          Length = 270

 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 71/277 (25%), Positives = 98/277 (35%), Gaps = 76/277 (27%)

Query: 85  PGPGSRRGGSPPTAFSPASETTF-LKFGVNAILSSGPRTETSPALLQSVPPKTFAF---P 140
           PGP +   G P  A +P  +      F +  IL  GP   T    L S P  +F     P
Sbjct: 6   PGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPS-PNSSFTSLVSP 64

Query: 141 YFEGSFQPF----IRSSYFPASSSVVPIPGTFSWPLAA-----------------RGKP- 178
           Y    ++P       S +  A+ +    PG F  PL                    GKP 
Sbjct: 65  YRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPL 124

Query: 179 ------RRGMLRR----AVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTAR 228
                 +R + +R      FS+ Q   LEK F+ QKY+S P+RK+LA  L L +      
Sbjct: 125 LWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSER----- 179

Query: 229 RTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGG 288
                                             QVK WFQNRR KWR  K+    S+  
Sbjct: 180 ----------------------------------QVKTWFQNRRAKWRRLKQENPQSNKK 205

Query: 289 CREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPS 325
              ++L +  +   DL     KG   +  +  P   S
Sbjct: 206 EELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPAS 242


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 85/345 (24%), Positives = 119/345 (34%), Gaps = 78/345 (22%)

Query: 18  RPTPTLTLPQSLQSAFSGHSSFLVEDLIR-ISRPPAYLPRSVPTASMSPPRQGAPTA-LT 75
           RP  +L  P S       H   L E  +R +S PP+  P         PP Q AP A   
Sbjct: 47  RPACSLQSPSSAGGHPKAHE--LSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQP 104

Query: 76  DTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTETSPALLQSVPPK 135
              A    +P P +     PP++ SP           NA  +  P       LL S    
Sbjct: 105 PQPAPQPPAPTPAAP---PPPSSASPPQ---------NASNNPTPANAAKSPLLNSPTVA 152

Query: 136 TFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKA 195
              FP+ + S Q   + +   +SSS     G  S P  A  K  R       ++  Q   
Sbjct: 153 KQIFPWMKESRQNTKQKT--SSSSSGESCAGDKSPPGQASSKRAR-----TAYTSAQLVE 205

Query: 196 LEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPF 255
           LEK F   +Y+ +P R ++A  L L +                                 
Sbjct: 206 LEKEFHFNRYLCRPRRVEMANLLNLTER-------------------------------- 233

Query: 256 FSPAGTFQVKIWFQNRRMKWRNSKERE--LLSSGGCREQTLPTKLNPHPDLSDVGQKGPG 313
                  Q+KIWFQNRRMK++  ++ +  L SSGG      P                PG
Sbjct: 234 -------QIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVP--------------PG 272

Query: 314 NEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSP 358
                    S  + + Y   S P   + P+    LPP+   +S P
Sbjct: 273 AGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLP 317


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 85/345 (24%), Positives = 119/345 (34%), Gaps = 78/345 (22%)

Query: 18  RPTPTLTLPQSLQSAFSGHSSFLVEDLIR-ISRPPAYLPRSVPTASMSPPRQGAPTA-LT 75
           RP  +L  P S       H   L E  +R +S PP+  P         PP Q AP A   
Sbjct: 47  RPACSLQSPSSAGGHPKAHE--LSEACLRTLSAPPSQPPSLGEPPLHPPPPQAAPPAPQP 104

Query: 76  DTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTETSPALLQSVPPK 135
              A    +P P +     PP++ SP           NA  +  P       LL S    
Sbjct: 105 PQPAPQPPAPTPAAP---PPPSSASPPQ---------NASNNPTPANAAKSPLLNSPTVA 152

Query: 136 TFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKA 195
              FP+ + S Q   + +   +SSS     G  S P  A  K  R       ++  Q   
Sbjct: 153 KQIFPWMKESRQNTKQKT--SSSSSGESCAGDKSPPGQASSKRAR-----TAYTSAQLVE 205

Query: 196 LEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPF 255
           LEK F   +Y+ +P R ++A  L L +                                 
Sbjct: 206 LEKEFHFNRYLCRPRRVEMANLLNLTER-------------------------------- 233

Query: 256 FSPAGTFQVKIWFQNRRMKWRNSKERE--LLSSGGCREQTLPTKLNPHPDLSDVGQKGPG 313
                  Q+KIWFQNRRMK++  ++ +  L SSGG      P                PG
Sbjct: 234 -------QIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVP--------------PG 272

Query: 314 NEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSP 358
                    S  + + Y   S P   + P+    LPP+   +S P
Sbjct: 273 AGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLP 317


>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
          Length = 387

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 43/139 (30%), Positives = 57/139 (41%), Gaps = 48/139 (34%)

Query: 171 PLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRT 230
           P+ A+ KPR+    R  FSD Q   LE+ F++QKY+S  DR  LAA L L D+       
Sbjct: 226 PVRAK-KPRKA---RTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDT------- 274

Query: 231 EPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKE--RELLSSGG 288
                                           QVK W+QNRR KW+       ELL+  G
Sbjct: 275 --------------------------------QVKTWYQNRRTKWKRQTAVGLELLAEAG 302

Query: 289 ---CREQTLPTKLNPHPDL 304
                ++  P+    HP L
Sbjct: 303 NYSALQRMFPSPYFYHPSL 321


>gi|13273317 homeobox B8 [Homo sapiens]
          Length = 243

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 43/152 (28%), Positives = 62/152 (40%), Gaps = 46/152 (30%)

Query: 168 FSW--PLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQD 225
           F W  P AA G+ RRG   R  +S  Q   LEK F    Y+++  R +++  LGL + Q 
Sbjct: 135 FPWMRPQAAAGR-RRG---RQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQ- 189

Query: 226 TARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLS 285
                                                 VKIWFQNRRMKW+    ++   
Sbjct: 190 --------------------------------------VKIWFQNRRMKWKKENNKDKFP 211

Query: 286 SGGCREQTL-PTKLNPHPDLSDVGQKGPGNEE 316
           S  C ++ L   KL   P+ +D G    G+++
Sbjct: 212 SSKCEQEELEKQKLERAPEAADEGDAQKGDKK 243


>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
          Length = 327

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 68/265 (25%), Positives = 90/265 (33%), Gaps = 60/265 (22%)

Query: 42  EDLIRISRPPAYL-PRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFS 100
           + L+   R P  L PRS  ++  S P       L        G+ GPG      P    +
Sbjct: 26  DPLLGDCRSPLELSPRSESSSDCSSPASPGRDCLETGTPRPGGASGPGLDSHLQPGQLSA 85

Query: 101 PA-SETTFLKFGVNAIL-------------SSGPRTETSPA-LLQSVPPKTFAFPYFEGS 145
           PA S T    F +  IL             SSG      P   L +   + F     +  
Sbjct: 86  PAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAAEDFRDKLDKSG 145

Query: 146 FQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKY 205
                 S Y         I  +   P     KPR+    R  F+D Q   LE+ F++QKY
Sbjct: 146 SNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKA---RTAFTDHQLAQLERSFERQKY 202

Query: 206 ISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVK 265
           +S  DR +LAA L L D+                                       QVK
Sbjct: 203 LSVQDRMELAASLNLTDT---------------------------------------QVK 223

Query: 266 IWFQNRRMKWRNSKE--RELLSSGG 288
            W+QNRR KW+       ELL+  G
Sbjct: 224 TWYQNRRTKWKRQTAVGLELLAEAG 248


>gi|4758168 distal-less homeobox 2 [Homo sapiens]
          Length = 328

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 39/101 (38%)

Query: 176 GKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPD 235
           GKP++    R ++S  Q  AL++ FQK +Y++ P+R +LAA LGL  +            
Sbjct: 147 GKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQT------------ 194

Query: 236 STPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWR 276
                                      QVKIWFQNRR K++
Sbjct: 195 ---------------------------QVKIWFQNRRSKFK 208


>gi|28912912 NK6 transcription factor related, locus 2 [Homo
           sapiens]
          Length = 277

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 32/102 (31%), Positives = 43/102 (42%), Gaps = 39/102 (38%)

Query: 185 RAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDSTPRPRASP 244
           R  FS  Q  ALEK F++ KY++ P+R +LA  LG+ +S                     
Sbjct: 152 RPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTES--------------------- 190

Query: 245 GAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSS 286
                             QVK+WFQNRR KWR     E+ S+
Sbjct: 191 ------------------QVKVWFQNRRTKWRKRHAAEMASA 214


>gi|210147470 NK2 transcription factor related, locus 6 [Homo
           sapiens]
          Length = 219

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 44/160 (27%), Positives = 64/160 (40%), Gaps = 47/160 (29%)

Query: 177 KPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPDS 236
           K R+    R +FS  Q  ALE+ F++Q+Y+S P+R+ LA+ L L  +             
Sbjct: 46  KARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTST------------- 92

Query: 237 TPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPT 296
                                     QVKIWFQNRR K +  ++ + L   G     L  
Sbjct: 93  --------------------------QVKIWFQNRRYKCKRQRQDKSLELAG---HPLTP 123

Query: 297 KLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDP 336
           +    P L   G+   G      GPG+P+    Y A+  P
Sbjct: 124 RRVAVPVLVRDGKPCLG-----PGPGAPAFPSPYSAAVSP 158


>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
          Length = 330

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 64/249 (25%), Positives = 86/249 (34%), Gaps = 83/249 (33%)

Query: 70  APTALTDTGASDLGSPG-PGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRT------ 122
           A T     GA   G PG PG   GG    +  P + +    + VN  L+ GP        
Sbjct: 64  AATGAGGAGAYGTGGPGGPGGPAGGGGACSMGPLTGS----YNVNMALAGGPGPGGGGGS 119

Query: 123 -----ETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPG-------TFSW 170
                  S A +  VP      P       P   ++  P   SV  +PG       TF W
Sbjct: 120 SGGAGALSAAGVIRVPAHR---PLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPW 176

Query: 171 ---------------PLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLA 215
                          P   R  P++   R + F+ +Q   LEK F +QKY++  +R  LA
Sbjct: 177 MESNRRYTKDRFTGHPYQNRTPPKKKKPRTS-FTRLQICELEKRFHRQKYLASAERAALA 235

Query: 216 AKLGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKW 275
             L + D+                                       QVK WFQNRR KW
Sbjct: 236 KALKMTDA---------------------------------------QVKTWFQNRRTKW 256

Query: 276 R--NSKERE 282
           R   ++ERE
Sbjct: 257 RRQTAEERE 265


>gi|148746211 NK2 transcription factor related, locus 3 [Homo
           sapiens]
          Length = 364

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 33/113 (29%), Positives = 47/113 (41%), Gaps = 39/113 (34%)

Query: 175 RGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAP 234
           R KPR     R +FS  Q   LE+ F++Q+Y+S P+R+ LA+ L L  +           
Sbjct: 142 RPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTST----------- 190

Query: 235 DSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSG 287
                                       QVKIWFQNRR K +  ++ + L  G
Sbjct: 191 ----------------------------QVKIWFQNRRYKCKRQRQDKSLELG 215


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 92/394 (23%), Positives = 129/394 (32%), Gaps = 77/394 (19%)

Query: 10   PAGYPSLLRPTPTLTLPQSLQSAFSG--HSSFLVEDLIRISRPPAYLPRSVPTASMSPPR 67
            PA  P    PTP    P SL+   +   H             P    P S      + P 
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKG--------APNPAVVTPPSPKGGPATSPP 1306

Query: 68   QGAPTALTDTGASDLGSPG-PGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTETS- 125
            +GAPT    T  S  GSPG P  +   +PP    P+ + T            GP T +S 
Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366

Query: 126  ---------------PALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPI-----P 165
                           PA+    P +  A P  +G           P S +V+P+     P
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD----------PTSPAVIPLSPKKAP 1416

Query: 166  GTFSWPLAARG--KPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDS 223
             T   P+   G   P +G L     + V  K       K    S P  K   A    K  
Sbjct: 1417 AT---PVTREGAATPSKGDLTPPAVTPVSLK-------KAPATSAP--KGGPATPSSKGD 1464

Query: 224  QDTARRTEPAPDSTPRPR--ASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKER 281
                  T P+P   P P+  A+  +P    A+P    A T    I    + +    S  R
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524

Query: 282  E-LLSSGGCREQTLPTKLNPHPDLSDVG------QKGPGNEEEEEGPGSPSHRLA----- 329
            + +  +     +  P  L P   L          +K P     +E P +PS + A     
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584

Query: 330  -----YHASSDPQHLRDPRLPGPLPPSPAHSSSP 358
                 Y  +  P+ L  P  P    PSP  + +P
Sbjct: 1585 VTPSTYKGAPSPKELLIP--PAVTSPSPKEAPTP 1616



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 58/227 (25%), Positives = 76/227 (33%), Gaps = 31/227 (13%)

Query: 50   PPAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPAS------ 103
            PPA  P S      +P  +GAPT    T  S  G P   S +G   P A +P S      
Sbjct: 965  PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024

Query: 104  ETTFLKFGVNAILSSGPRTETSPAL------LQSVPPKTF-------AFPYFEGSFQPFI 150
             T F K       ++ P  + SPA         + P  T        A P  +G+  P  
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084

Query: 151  RSSYFPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPD 210
             +   P      P P     P AA     +G L              K        + P 
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP---------HKGAPTTPAATPPS 1135

Query: 211  RKKLAAKLGLKDSQDTARRTEPAPD---STPRPRASPGAPDLTSASP 254
             K   A    K +  T   T P+P    +TP P+ +P  P  T  SP
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 68/263 (25%), Positives = 91/263 (34%), Gaps = 40/263 (15%)

Query: 3    FP-GLLAPPAGYPSLLRPTPTLT-LPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPT 60
            FP G   PPA  P   + +P  T LP+   +                  P A LP S   
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAATPLPKGAPTT-----------------PAATLP-SPKG 1069

Query: 61   ASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGP 120
               +P  +GAPT    T  S  G P   S +G   P A +P S     K G+      G 
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP----KGGLATPPHKG- 1124

Query: 121  RTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIP-GTFSWPLAARGKPR 179
               T+PA     P    A P  +G+      +   P      P P G  + P A    P+
Sbjct: 1125 -APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183

Query: 180  RGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPD---S 236
             G+   +           K        + P  K   A    K +  T   T P+P    +
Sbjct: 1184 GGLATPS----------PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233

Query: 237  TPRPRASPGAPDLTSASPFFSPA 259
            TP P+ +P  P  T  SP   PA
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPA 1256



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 74/312 (23%), Positives = 100/312 (32%), Gaps = 66/312 (21%)

Query: 51   PAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKF 110
            PA  P S      +PP +GAPT    T  S  G     S +G     A +P S     K 
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP----KG 1207

Query: 111  GVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSW 170
            G+      G    T+PA     P    A P  +G+      +   P      P P     
Sbjct: 1208 GLATPSPKG--APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265

Query: 171  PLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRT 230
            P AA     +G L           A+         ++ P  K   A    K +      T
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAV---------VTPPSPKGGPATSPPKGAPTPPAAT 1316

Query: 231  EPAP---DSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSG 287
             P+P     TP P+ +P  P +T  SP  +P                             
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP----------------------------- 1347

Query: 288  GCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGP----GSPSHRLAYHASSDPQHLRDPR 343
                 TLP         +   + GP     +EGP     +PSH+    A + P   R P 
Sbjct: 1348 -----TLPA-------TTPSSKGGPTTPSSKEGPTPPAATPSHK-GGPAMTPPSPKRGPA 1394

Query: 344  LPGPL--PPSPA 353
            +P P   P SPA
Sbjct: 1395 IPSPKGDPTSPA 1406



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 51/208 (24%), Positives = 70/208 (33%), Gaps = 39/208 (18%)

Query: 50   PPAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLK 109
            PPA  P S      +P  + APT    T  S  G P   S +G   P A +P S      
Sbjct: 942  PPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP----- 996

Query: 110  FGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFS 169
                     GP T  SP    + P  T   P    +  PF + +  P +++         
Sbjct: 997  -------KGGPAT-PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT--------- 1039

Query: 170  WPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARR 229
             P + +G P                 L K        + P  K   A   LK +      
Sbjct: 1040 -PPSPKGSP-------------AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085

Query: 230  TEPAP---DSTPRPRASPGAPDLTSASP 254
            T P+P    +TP P+ +P  P  T  SP
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATPPSP 1113



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 49/201 (24%), Positives = 70/201 (34%), Gaps = 26/201 (12%)

Query: 64   SPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVNAILSSGPRTE 123
            SP    +PT  +  GA    +  P S +G + P   +P      L F      +  P+  
Sbjct: 849  SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA 908

Query: 124  TSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLAARGKPRRGML 183
             + ++  S P K  A P  +G           PAS S    P     P A    P+ G  
Sbjct: 909  PALSMTSSSPKKARATPAPKG----------IPASPSPKGAPTP---PAATPPSPKGGPA 955

Query: 184  RRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPD---STPRP 240
              +           K        + P  K   A    K +      T P+P    +TP P
Sbjct: 956  TPS----------PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005

Query: 241  RASPGAPDLTSASPFFSPAGT 261
            + +P  P +T  SP  SPA T
Sbjct: 1006 KGAPTPPAVTPPSPKGSPAAT 1026



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 76/312 (24%), Positives = 106/312 (33%), Gaps = 100/312 (32%)

Query: 54  LPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGSRRGGSPPTAFSPASETTFLKFGVN 113
           +P+SVP+ S+ PP    P      G S   +  P +      PT  S AS T   K G  
Sbjct: 730 IPKSVPSPSL-PPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSK-GTL 787

Query: 114 AILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVPIPGTFSWPLA 173
             L+  P    SP L  SV P+T   P  +GS  P   +     SS V P+  +F     
Sbjct: 788 TYLADSP----SP-LGVSVSPQTKRPPTKKGSAGP--DTPIGNLSSPVSPVEASFL---- 836

Query: 174 ARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPA 233
               P   +                 FQ                 G KDS        PA
Sbjct: 837 ----PENSL----------------SFQ-----------------GSKDS--------PA 851

Query: 234 PDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGGCREQT 293
              +P P +  GAP  ++ +P  SP G                                T
Sbjct: 852 TTHSPTPPSPKGAPTPSAVTPL-SPKGV-------------------------------T 879

Query: 294 LPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLA---YHASSDPQHLRDPRLPGPLPP 350
           LP K  P P + ++          +EGP +P+ + A      SS P+  R    P  +P 
Sbjct: 880 LPPKETPTPSVVNL-------PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA 932

Query: 351 SPAHSSSPGKPS 362
           SP+   +P  P+
Sbjct: 933 SPSPKGAPTPPA 944



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 66/273 (24%), Positives = 103/273 (37%), Gaps = 51/273 (18%)

Query: 8    APPAGYPSLLRPTPT---LTLPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPTASMS 64
            +PPA  PS  +  P+   L +P ++ S     +            PPA  P S      +
Sbjct: 1581 SPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP----------TPPAVTPPSPEKGPAT 1630

Query: 65   PPRQGAPTALTDTGASDLGSP-GPGS---RRGGSPPTA-----------------FSPAS 103
            P  +G PT+   T +S   SP  P S   + G + P A                  +PA 
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690

Query: 104  ETTFLKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPASSSVVP 163
            E+T +   + A    GP+T+ S A    + P   A     GS  P   S+  PA   ++P
Sbjct: 1691 ESTPI---ITAPTRKGPQTKKSSATSPPICPDPSA---KNGSKGPL--STVAPA--PLLP 1740

Query: 164  IPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQK--QKYISKPDRKKLAAKLGLK 221
            +    S    A+GK       +   +  + KA   +     +K + KP+   ++A     
Sbjct: 1741 VQKDSS--KTAKGKD-ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPP 1797

Query: 222  DSQDTARRTEPAPDSTPRPRASPGAPDLTSASP 254
             S   A    P P   P+ +  P +P L   SP
Sbjct: 1798 VSLPLA--PSPVPTLPPKQQFLPSSPGLVLESP 1828


>gi|157426823 NK2 homeobox 4 [Homo sapiens]
          Length = 354

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 53/194 (27%), Positives = 72/194 (37%), Gaps = 59/194 (30%)

Query: 173 AARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEP 232
           AA   PRR   RR +FS  Q   LE+ F++QKY+S P+R+ LA+ + L            
Sbjct: 183 AAAAAPRRK--RRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHL------------ 228

Query: 233 APDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKW-RNSKER---ELLSSGG 288
               TP                        QVKIWFQN R K  R +K++   +L   GG
Sbjct: 229 ----TPT-----------------------QVKIWFQNHRYKMKRQAKDKAAQQLQQEGG 261

Query: 289 CREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDPQHLRDPRLPGPL 348
                 P    P P    V       +  + G  +P+   A            P+ P P 
Sbjct: 262 LGPPPPPP---PSPRRVAVPVLVKDGKPCQNGASTPTPGQA-----------GPQPPAPT 307

Query: 349 PPSPAHSSSPGKPS 362
           P       SP  P+
Sbjct: 308 PAPELEELSPSPPA 321


>gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
          Length = 255

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 44/113 (38%)

Query: 176 GKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEPAPD 235
           GK ++    R ++S +Q +AL + FQ+ +Y++ P+R +LAA LGL  +            
Sbjct: 123 GKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQT------------ 170

Query: 236 STPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGG 288
                                      QVKIWFQN+R     SK ++L+  GG
Sbjct: 171 ---------------------------QVKIWFQNKR-----SKFKKLMKQGG 191


>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
          Length = 324

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 39/116 (33%)

Query: 173 AARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLGLKDSQDTARRTEP 232
           A R + RR    R +FS  Q   LE+ F++Q+Y+S P+R +LA+ L L  +         
Sbjct: 130 AERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTST--------- 180

Query: 233 APDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNSKERELLSSGG 288
                                         QVKIWFQNRR K +  ++ + L   G
Sbjct: 181 ------------------------------QVKIWFQNRRYKCKRQRQDQTLELVG 206


>gi|118766339 thyroid transcription factor 1 isoform 1 [Homo
           sapiens]
          Length = 401

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 57/220 (25%), Positives = 84/220 (38%), Gaps = 75/220 (34%)

Query: 158 SSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAK 217
           S ++ P+P            PRR   RR +FS  Q   LE+ F++QKY+S P+R+ LA+ 
Sbjct: 180 SKNMAPLPSA----------PRRK--RRVLFSQAQVYELERRFKQQKYLSAPEREHLASM 227

Query: 218 LGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKW-R 276
           + L                TP                        QVKIWFQN R K  R
Sbjct: 228 IHL----------------TPT-----------------------QVKIWFQNHRYKMKR 248

Query: 277 NSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDP 336
            +K++         +Q L           D G  G G      G G P  + A   S  P
Sbjct: 249 QAKDK-------AAQQQLQ---------QDSGGGGGGG-----GTGCPQQQQAQQQS--P 285

Query: 337 QHLRDPRLPGPLPPSPAHSSSPGKPSDFSDSEEEEEGEEQ 376
           + +  P L     P  A + +PG  S    ++++ + + Q
Sbjct: 286 RRVAVPVLVKDGKPCQAGAPAPGAASLQGHAQQQAQHQAQ 325


>gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]
          Length = 371

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 57/220 (25%), Positives = 84/220 (38%), Gaps = 75/220 (34%)

Query: 158 SSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAK 217
           S ++ P+P            PRR   RR +FS  Q   LE+ F++QKY+S P+R+ LA+ 
Sbjct: 150 SKNMAPLPSA----------PRRK--RRVLFSQAQVYELERRFKQQKYLSAPEREHLASM 197

Query: 218 LGLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKW-R 276
           + L                TP                        QVKIWFQN R K  R
Sbjct: 198 IHL----------------TPT-----------------------QVKIWFQNHRYKMKR 218

Query: 277 NSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGSPSHRLAYHASSDP 336
            +K++         +Q L           D G  G G      G G P  + A   S  P
Sbjct: 219 QAKDK-------AAQQQLQ---------QDSGGGGGGG-----GTGCPQQQQAQQQS--P 255

Query: 337 QHLRDPRLPGPLPPSPAHSSSPGKPSDFSDSEEEEEGEEQ 376
           + +  P L     P  A + +PG  S    ++++ + + Q
Sbjct: 256 RRVAVPVLVKDGKPCQAGAPAPGAASLQGHAQQQAQHQAQ 295


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 64/244 (26%), Positives = 82/244 (33%), Gaps = 77/244 (31%)

Query: 50  PPAYLPRS----VPTASMSPPRQGAP-TALTDTGASDLGSPGPGSRRGG------SPPTA 98
           PP Y   S    V  A   P   GAP  A  D  A+  G PGP +           PP  
Sbjct: 39  PPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWAAAYG-PGPAAPAASPASLAFGPPPD 97

Query: 99  FSPASETTFLKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSYFPAS 158
           FSP         G+ A    GP T +SP   +  P +             ++R S     
Sbjct: 98  FSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQRPTPYE-------------WMRRSVAAGG 144

Query: 159 SSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKL 218
                            GK R     R V++D QR  LEK F   +YI+   + +LAA L
Sbjct: 145 GG-------------GSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANL 191

Query: 219 GLKDSQDTARRTEPAPDSTPRPRASPGAPDLTSASPFFSPAGTFQVKIWFQNRRMKWRNS 278
           GL +                                        QVKIWFQNRR K R  
Sbjct: 192 GLTER---------------------------------------QVKIWFQNRRAKERKV 212

Query: 279 KERE 282
            +++
Sbjct: 213 NKKK 216


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,746,855
Number of Sequences: 37866
Number of extensions: 1342688
Number of successful extensions: 12284
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 275
Number of HSP's successfully gapped in prelim test: 487
Number of HSP's that attempted gapping in prelim test: 9816
Number of HSP's gapped (non-prelim): 2763
length of query: 382
length of database: 18,247,518
effective HSP length: 104
effective length of query: 278
effective length of database: 14,309,454
effective search space: 3978028212
effective search space used: 3978028212
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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