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Search of human proteins with 71044479
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71044479 death inducer-obliterator 1 isoform c [Homo
sapiens]
(2240 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 4554 0.0
gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens] 2374 0.0
gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens] 1082 0.0
gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens] 1082 0.0
gi|7662018 PHD finger protein 3 [Homo sapiens] 235 4e-61
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 130 2e-29
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 114 1e-24
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 110 2e-23
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 110 2e-23
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 107 1e-22
gi|47271475 SPOC domain containing 1 [Homo sapiens] 107 1e-22
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 105 4e-22
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 105 4e-22
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 102 6e-21
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 101 7e-21
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 100 2e-20
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 96 4e-19
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 96 4e-19
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 94 1e-18
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 93 3e-18
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 91 1e-17
gi|52426743 cisplatin resistance-associated overexpressed protei... 87 2e-16
gi|19923485 cisplatin resistance-associated overexpressed protei... 87 2e-16
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 87 2e-16
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 87 2e-16
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 86 3e-16
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 84 2e-15
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 83 3e-15
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 83 3e-15
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 83 3e-15
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 4554 bits (11813), Expect = 0.0
Identities = 2240/2240 (100%), Positives = 2240/2240 (100%)
Query: 1 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
Sbjct: 1 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
Query: 61 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
Sbjct: 61 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
Query: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
Sbjct: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
Query: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
Sbjct: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
Query: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
Sbjct: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
Query: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
Sbjct: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
Query: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
Sbjct: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
Query: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
Sbjct: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
Query: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK 540
KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
Sbjct: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK 540
Query: 541 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL 600
AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
Sbjct: 541 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL 600
Query: 601 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS 660
SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
Sbjct: 601 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS 660
Query: 661 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR 720
AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
Sbjct: 661 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR 720
Query: 721 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME 780
YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
Sbjct: 721 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME 780
Query: 781 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT 840
SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
Sbjct: 781 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT 840
Query: 841 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD 900
TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
Sbjct: 841 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD 900
Query: 901 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT 960
EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
Sbjct: 901 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT 960
Query: 961 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP 1020
VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
Sbjct: 961 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP 1020
Query: 1021 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF 1080
DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
Sbjct: 1021 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF 1080
Query: 1081 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF 1140
DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
Sbjct: 1081 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF 1140
Query: 1141 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIK 1200
SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIK
Sbjct: 1141 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIK 1200
Query: 1201 RPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGS 1260
RPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGS
Sbjct: 1201 RPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGS 1260
Query: 1261 PPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPLEHILQT 1320
PPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPLEHILQT
Sbjct: 1261 PPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPLEHILQT 1320
Query: 1321 LFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFSKDKALEEEE 1380
LFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFSKDKALEEEE
Sbjct: 1321 LFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFSKDKALEEEE 1380
Query: 1381 DDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDETILEEAKVT 1440
DDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDETILEEAKVT
Sbjct: 1381 DDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDETILEEAKVT 1440
Query: 1441 VDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLEEQEEAL 1500
VDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLEEQEEAL
Sbjct: 1441 VDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLEEQEEAL 1500
Query: 1501 RQQRAAVGVSMAHFSVSDALMSPPPKSSLPKAELFQQEQQSADKPASLPPASQASNHRDP 1560
RQQRAAVGVSMAHFSVSDALMSPPPKSSLPKAELFQQEQQSADKPASLPPASQASNHRDP
Sbjct: 1501 RQQRAAVGVSMAHFSVSDALMSPPPKSSLPKAELFQQEQQSADKPASLPPASQASNHRDP 1560
Query: 1561 RQARRLAAETGEGEGEPLSRLSARGAQGALPERDASRGGLVGQAPMPVPEEKEPASSPWA 1620
RQARRLAAETGEGEGEPLSRLSARGAQGALPERDASRGGLVGQAPMPVPEEKEPASSPWA
Sbjct: 1561 RQARRLAAETGEGEGEPLSRLSARGAQGALPERDASRGGLVGQAPMPVPEEKEPASSPWA 1620
Query: 1621 SGEKPPAGSEQDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGALQPGFPLQHDGER 1680
SGEKPPAGSEQDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGALQPGFPLQHDGER
Sbjct: 1621 SGEKPPAGSEQDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGALQPGFPLQHDGER 1680
Query: 1681 DPFTCPGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPG 1740
DPFTCPGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPG
Sbjct: 1681 DPFTCPGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPG 1740
Query: 1741 QKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIASNDGPRGPPPARF 1800
QKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIASNDGPRGPPPARF
Sbjct: 1741 QKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIASNDGPRGPPPARF 1800
Query: 1801 GAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAPY 1860
GAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAPY
Sbjct: 1801 GAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAPY 1860
Query: 1861 NEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPPP 1920
NEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPPP
Sbjct: 1861 NEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPPP 1920
Query: 1921 GHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPGPRGIQPQQFEDQRVHSPPRFTN 1980
GHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPGPRGIQPQQFEDQRVHSPPRFTN
Sbjct: 1921 GHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPGPRGIQPQQFEDQRVHSPPRFTN 1980
Query: 1981 QRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKDR 2040
QRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKDR
Sbjct: 1981 QRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKDR 2040
Query: 2041 WEEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPL 2100
WEEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPL
Sbjct: 2041 WEEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPL 2100
Query: 2101 EEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDRE 2160
EEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDRE
Sbjct: 2101 EEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDRE 2160
Query: 2161 READRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKES 2220
READRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKES
Sbjct: 2161 READRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKES 2220
Query: 2221 ARDPKPEASRASDAGTASQA 2240
ARDPKPEASRASDAGTASQA
Sbjct: 2221 ARDPKPEASRASDAGTASQA 2240
>gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]
Length = 1189
Score = 2374 bits (6153), Expect = 0.0
Identities = 1181/1181 (100%), Positives = 1181/1181 (100%)
Query: 1 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
Sbjct: 1 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
Query: 61 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
Sbjct: 61 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
Query: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
Sbjct: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
Query: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
Sbjct: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
Query: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
Sbjct: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
Query: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
Sbjct: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
Query: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
Sbjct: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
Query: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
Sbjct: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
Query: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK 540
KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK
Sbjct: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEK 540
Query: 541 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL 600
AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL
Sbjct: 541 AAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWL 600
Query: 601 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS 660
SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS
Sbjct: 601 SATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMS 660
Query: 661 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR 720
AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR
Sbjct: 661 AAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNR 720
Query: 721 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME 780
YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME
Sbjct: 721 YKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVME 780
Query: 781 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT 840
SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT
Sbjct: 781 SRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDT 840
Query: 841 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD 900
TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD
Sbjct: 841 TSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSAD 900
Query: 901 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT 960
EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT
Sbjct: 901 EVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTT 960
Query: 961 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP 1020
VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP
Sbjct: 961 VTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSP 1020
Query: 1021 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF 1080
DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF
Sbjct: 1021 DPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCF 1080
Query: 1081 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF 1140
DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF
Sbjct: 1081 DYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYF 1140
Query: 1141 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181
SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG
Sbjct: 1141 SSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181
Score = 36.6 bits (83), Expect = 0.28
Identities = 41/170 (24%), Positives = 66/170 (38%), Gaps = 27/170 (15%)
Query: 1212 DEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEPP 1271
D ++PE+ P+ P + E + S+ + A+ T PPGS P P
Sbjct: 508 DHNYNAVKPEKTAAPS-PSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNL 566
Query: 1272 VLKVLSSLKPAAPSPATAATTAAAAST--------AASSTASSASKTASPLEHILQTLFG 1323
V K S AA +PA + T A S+ +SA++ A P
Sbjct: 567 VPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGP---------- 616
Query: 1324 KKKSFDPSAREPPGSTA--GLPQEPKTTAEDGVPAPPLLDPIVQQFGQFS 1371
+ ++++ PGS A G ++P VP+ P+ P + G S
Sbjct: 617 APAAATAASKKFPGSAALVGAVRKPV------VPSVPMASPAPGRLGAMS 660
Score = 31.6 bits (70), Expect = 9.2
Identities = 42/183 (22%), Positives = 71/183 (38%), Gaps = 20/183 (10%)
Query: 1184 SPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSK 1243
+P+ + V + +K +S D + + PE A P+VA+ P E +
Sbjct: 868 APKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPE-----AVPEVASEPGLES--AS 920
Query: 1244 YPLCSADAAVSTTPPGSP-PPPPPL----PEPP------VLKVLSSLKPAAPSPATAATT 1292
+P + D PPG P P PL P P V V S + +P+++ T
Sbjct: 921 HP--NVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTA 978
Query: 1293 AAAASTAASSTASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAED 1352
A+A++ ST ++ P + + K PS+ P + P +T+E
Sbjct: 979 VASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSES 1038
Query: 1353 GVP 1355
P
Sbjct: 1039 RSP 1041
>gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens]
Length = 562
Score = 1082 bits (2798), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
Sbjct: 1 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
Query: 61 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
Sbjct: 61 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
Query: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
Sbjct: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
Query: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
Sbjct: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
Query: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
Sbjct: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
Query: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
Sbjct: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
Query: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
Sbjct: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
Query: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
Sbjct: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
Query: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK 529
KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK
Sbjct: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK 529
>gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens]
Length = 562
Score = 1082 bits (2798), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS
Sbjct: 1 MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLS 60
Query: 61 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE
Sbjct: 61 LRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASE 120
Query: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP
Sbjct: 121 TRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERP 180
Query: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG
Sbjct: 181 LKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEG 240
Query: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS
Sbjct: 241 KAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGIS 300
Query: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS
Sbjct: 301 EARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKS 360
Query: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK
Sbjct: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
Query: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK
Sbjct: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVK 480
Query: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK 529
KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK
Sbjct: 481 KAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYK 529
>gi|7662018 PHD finger protein 3 [Homo sapiens]
Length = 2039
Score = 235 bits (599), Expect = 4e-61
Identities = 255/952 (26%), Positives = 388/952 (40%), Gaps = 179/952 (18%)
Query: 942 PLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKP 1001
P++DLSP V V V+ + S A++S ++ S E +Q+ PK
Sbjct: 1128 PVDDLSP------KKVKVVVGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKS 1181
Query: 1002 VLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFI 1061
SP PR P P ES FL+RL+ IWKGFI
Sbjct: 1182 TF---------------SPAPR----PEMPGTVEVEST---------FLARLNFIWKGFI 1213
Query: 1062 NMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIR 1121
NM SVAKFVTKAYPVSG +YL+EDLPD+I +GGRI+P+TVWDYV K+K+S +KE+C++R
Sbjct: 1214 NMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVR 1273
Query: 1122 FHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181
F P TEE++++Y L++YFSSR R+GV ANN + VKD+YLIPL A D +P L+PF+GPG
Sbjct: 1274 FTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATDKIPHPLVPFDGPG 1333
Query: 1182 LESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKP 1241
LE RPN++LGL+I QK+KR
Sbjct: 1334 LELHRPNLLLGLIIRQKLKR---------------------------------------- 1353
Query: 1242 SKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAAS 1301
++ C++ + ++ TP +PP P + ++V + P + + T
Sbjct: 1354 -QHSACASTSHIAETPESAPPIALPPDKKSKIEVSTEEAPEEENDFFNSFTTVLHKQRNK 1412
Query: 1302 STASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKT--TAEDGVPAPPL 1359
+ + +E +++ K+ R PG G +P T A +P +
Sbjct: 1413 PQQNLQEDLPTAVEPLMEV---TKQEPPKPLRFLPGVLIGWENQPTTLELANKPLPVDDI 1469
Query: 1360 LDPIVQQFGQ-FSKDKALEEEE--DDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEA 1416
L ++ GQ + + +++ E+ + P+ E+ D V G E++ +
Sbjct: 1470 LQSLLGTTGQVYDQAQSVMEQNTVKEIPFLNEQTNSKIEKTDNVEVTDGENKEIKVKVDN 1529
Query: 1417 AAAEREEVAYDPEDET-ILEEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQ 1475
+ ++ A E ET ++ + ++ L + +P + A +L Q
Sbjct: 1530 ISESTDKSA---EIETSVVGSSSISAGSLTSLSLRG-------KPPDVSTEAFLTNLSIQ 1579
Query: 1476 QKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGVSMAHFSVSDALMSPPPKSSLPKAELF 1535
K E + + + KRQL+E +E Q + S P +S++ K +
Sbjct: 1580 SKQEETVESKEKTLKRQLQEDQENNLQD-------------NQTSNSSPCRSNVGKGNID 1626
Query: 1536 QQEQQSADKPASLPPASQASN-HRDPRQA--RRLAAETGEGEGEPLSRLSARGAQGALPE 1592
S + A+ + Q N RDPRQA R T E + R G + LP
Sbjct: 1627 GNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCR---NGEKHMLPG 1683
Query: 1593 RDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAGSEQDGWKAEPGEGTRPATVGDSSA 1652
++ L Q + EEK S EK + D K + + S A
Sbjct: 1684 LSHNKEHLTEQINV---EEK------LCSAEKNSCVQQSDNLKVAQNSPS-VENIQTSQA 1733
Query: 1653 RPARRVLLPTPPCGALQPGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRS 1712
A+ LQ +Q+ PF + A+ ++ +E S S
Sbjct: 1734 EQAK----------PLQEDILMQNIETVHPF------RRGSAVATSHFEVGNTCPSEFPS 1777
Query: 1713 SSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFP 1772
S T R R +P+ P QP Q + P G FP
Sbjct: 1778 KS---ITFTSRSTSPRTSTNFSPMRP-------QQPNLQHLKSSPP---------GFPFP 1818
Query: 1773 GPRGPAPPFPEENIASNDGPRGP---PPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPS 1829
GP P FP +++ P PP FG + P+ H P GP
Sbjct: 1819 GP----PNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQ 1874
Query: 1830 YLGGPRGVAPSQFEERK----------DPHGEKREFQ-DAPYNEVTGAPAQF 1870
R + P F + K DP G + + Q D P+N G +F
Sbjct: 1875 ---ASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRF 1923
Score = 177 bits (449), Expect = 1e-43
Identities = 109/283 (38%), Positives = 156/283 (55%), Gaps = 21/283 (7%)
Query: 660 SAAPSQPNS-QIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718
+A+ S+P++ QIRQ++R SLK+IL KR+ DS+ L + E + K+A IEKE+F+ F+ TD
Sbjct: 916 AASASKPSADQIRQSVRHSLKDILMKRLTDSN-LKVPEEKAAKVATKIEKELFSFFRDTD 974
Query: 719 NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSV 778
+YK+KYRS+MFNLKDPKN LF +VL+ E++ L+R+ PEEL SKEL+ W+ R R
Sbjct: 975 AKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHT 1034
Query: 779 MESRTKLHNESKK---TAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKS------TAPL 829
+E K E ++ T + ++E P+ + E E KS +
Sbjct: 1035 IEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLEKPEGSEKQ 1094
Query: 830 LDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDS 889
+ SM KDTTSQHR HLFDLNCKIC G++ D+ +PKK K+ V + KH
Sbjct: 1095 KEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVVVGVAR-----KHSD 1149
Query: 890 SAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYFPGP 932
+ + D+ E E ES T+ P P
Sbjct: 1150 NEAESIADALSSTSNILASEFFEEEKQESPK-----STFSPAP 1187
Score = 72.4 bits (176), Expect = 5e-12
Identities = 67/291 (23%), Positives = 125/291 (42%), Gaps = 49/291 (16%)
Query: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323
+ P+ C++PH NRFM+ C RC++WFHGDCVG+S ++ + + ++Y+C C
Sbjct: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770
Query: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377
+++ +E D Q ++ GD +C +G + + ++ D+ K + +
Sbjct: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822
Query: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437
K K+KI + + G G +S C ++ I K A ++ + +
Sbjct: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867
Query: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAA 497
+EK + P++ + C G K S E K+ V+K V L A
Sbjct: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGV--------LNVHPA 916
Query: 498 CESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASK 548
+S PS + ++ + L+ + T + + E+ AA A+K
Sbjct: 917 ASASKPS------ADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATK 961
Score = 70.9 bits (172), Expect = 1e-11
Identities = 74/280 (26%), Positives = 115/280 (41%), Gaps = 38/280 (13%)
Query: 1964 PQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQA---PQVMK 2020
P +F + + R T+ R F +R P + + +P F F G PQ M
Sbjct: 1772 PSEFPSKSITFTSRSTSPRTST--NFSPMRPQQPNLQHLKSSPPGFPFPGPPNFPPQSMF 1829
Query: 2021 PGPRPLLELPSHPP------QHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGK 2074
P P L P PP Q+ W PP PGQ G + A G
Sbjct: 1830 GFP-PHLPPPLLPPPGFGFAQNPMVPW----PPVV---HLPGQPQRMMGPLSQASRYIGP 1881
Query: 2075 GHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRER---DWDR 2131
+ Y+ + +R D ++ + R DR+R + RER +W++
Sbjct: 1882 QNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQ 1941
Query: 2132 PREWDRHRDKDSSRDWDRNRERSANRDRER----EADRGKEWDRSRERSRNRERERDRRR 2187
E R RD+ +D DR ++D+ER DRG + SR+ SRN +++ D+ +
Sbjct: 1942 ESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPK 2000
Query: 2188 DRDRSRSRERDRDKARDRE---------RGRDRKDRSKSK 2218
D + +ER+ K++ RE + RD DR+KSK
Sbjct: 2001 SEDYEKDKERE--KSKHREGEKDRDRYHKDRDHTDRTKSK 2038
Score = 61.6 bits (148), Expect = 8e-09
Identities = 65/243 (26%), Positives = 92/243 (37%), Gaps = 31/243 (12%)
Query: 1993 RGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSS 2052
R S FS Q P+ H + P PGP P+ PPQ + PP L
Sbjct: 1790 RTSTNFSPMRPQQPNLQHLKSSPPGFPFPGP------PNFPPQSMFG-FPPHLPPPLLPP 1842
Query: 2053 SAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASED 2112
G W G+ Q R+ +GP+ + +
Sbjct: 1843 PGFGFAQNPMVPWPPVVHLPGQPQRMMGPL---SQASRY-IGPQNFY--------QVKDI 1890
Query: 2113 RRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRS 2172
RR ER W R+ R ++R + DR R S + +RE KEW++
Sbjct: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKG-------DRQRFYSDSHHLKRERHE-KEWEQE 1942
Query: 2173 RERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESAR--DPKPEASR 2230
ER R R+R +D +DRDR E +DK R R DR K+ +R D KP+ +
Sbjct: 1943 SERHRRRDRSQD--KDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPK 2000
Query: 2231 ASD 2233
+ D
Sbjct: 2001 SED 2003
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 130 bits (326), Expect = 2e-29
Identities = 65/142 (45%), Positives = 96/142 (67%), Gaps = 1/142 (0%)
Query: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
+++ER ++ + + E + R +R RERER R +E++ +R RE DR RD+ R
Sbjct: 298 KEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKER 357
Query: 2146 DWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDR 2205
D DR+RER +RDRER +DR K+ RSRE+SR+RERER+R R+R+R R RER+R++ R+R
Sbjct: 358 DRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERER 417
Query: 2206 ERGRDRKDRSKSKESARDPKPE 2227
ER R+R +R K K+ R+ E
Sbjct: 418 ERERER-EREKDKKRDREEDEE 438
Score = 121 bits (303), Expect = 9e-27
Identities = 62/138 (44%), Positives = 91/138 (65%), Gaps = 5/138 (3%)
Query: 2084 EGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDS 2143
E R+RER +E+ E + + +R RE+E+ R RERD DR R +R RD+D
Sbjct: 308 ERRERER----ERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDR 363
Query: 2144 SRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKAR 2203
RD DR+RERS++R+++R R K DR RER R RERER+R R+R+R R RER+R++ R
Sbjct: 364 ERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERER 423
Query: 2204 DRERGRDRKDRSKSKESA 2221
+RE+ + ++DR + +E A
Sbjct: 424 EREKDK-KRDREEDEEDA 440
Score = 117 bits (293), Expect = 1e-25
Identities = 58/143 (40%), Positives = 88/143 (61%), Gaps = 1/143 (0%)
Query: 2072 EGKGH-EYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWD 2130
E KG E Q E +RER +E+ E + + +R +E+ER R R+RD D
Sbjct: 293 EEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRD 352
Query: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRD 2190
R +E DR RD++ RD DR R N+DR R ++ ++ +R RER R RERER+R R+R+
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERE 412
Query: 2191 RSRSRERDRDKARDRERGRDRKD 2213
R R RER+R++ R++++ RDR++
Sbjct: 413 REREREREREREREKDKKRDREE 435
Score = 111 bits (277), Expect = 9e-24
Identities = 63/165 (38%), Positives = 94/165 (56%), Gaps = 10/165 (6%)
Query: 2060 EADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERER 2119
E + Q + RE + R + R+RER +EK E +R R+R+R
Sbjct: 299 EKERQEIEKERRERERERERERERREREREREREREREKEKER-------ERERERDRDR 351
Query: 2120 GRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNR 2179
R R+RD DR R+ DR R++ S R+ DR+R R +RDRERE +R +E +R RER R R
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411
Query: 2180 ERERDRRRDRDRSRSRERDRDKARDRERGRDRKD---RSKSKESA 2221
ERER+R R+R+R R +++ RD+ D E +R+ + + KE+A
Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAA 456
Score = 107 bits (267), Expect = 1e-22
Identities = 63/145 (43%), Positives = 88/145 (60%), Gaps = 17/145 (11%)
Query: 2094 GPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRER 2153
G KEK +E E RRERER R RER +R RE +R R+++ ++ +R RER
Sbjct: 296 GKKEKERQE-------IEKERRERERERERERERR-EREREREREREREKEKERERERER 347
Query: 2154 SANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDR-- 2211
+RDR +E DR DR RER R+R+RER R++DRSRSRE+ RD+ R+RER R+R
Sbjct: 348 DRDRDRTKERDR----DRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERER 403
Query: 2212 ---KDRSKSKESARDPKPEASRASD 2233
++R + +E R+ + E R D
Sbjct: 404 EREREREREREREREREREREREKD 428
Score = 94.0 bits (232), Expect = 2e-18
Identities = 52/119 (43%), Positives = 77/119 (64%), Gaps = 11/119 (9%)
Query: 2113 RRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRS 2172
++ E E+G+ ++ ++ R ++ R+ +R RER R+RERE +R +E ++
Sbjct: 289 KKLEEEKGKKEKERQEIEKER-------RERERERERERERR-EREREREREREREKEKE 340
Query: 2173 RERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDR-KDRSKSKESARDPKPEASR 2230
RER R R+R+RDR ++RDR R RERDRD RDRER DR KDRS+S+E +RD + E R
Sbjct: 341 RERERERDRDRDRTKERDRDRDRERDRD--RDRERSSDRNKDRSRSREKSRDRERERER 397
Score = 77.4 bits (189), Expect = 1e-13
Identities = 44/162 (27%), Positives = 83/162 (51%), Gaps = 2/162 (1%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDWDRP 2132
K E + R R+R +++ E + D S DR ++R R R SR+R+ +R
Sbjct: 337 KEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERE 396
Query: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRS 2192
RE +R R+++ R+ +R RER R+RERE D+ ++ + E + R + + R+++ +
Sbjct: 397 REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAA 456
Query: 2193 RSRERDRDKARDRERGRD-RKDRSKSKESARDPKPEASRASD 2233
+ R+R++ R+ K+ + +E R+ EA R +
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE 498
Score = 66.6 bits (161), Expect = 3e-10
Identities = 49/150 (32%), Positives = 76/150 (50%), Gaps = 15/150 (10%)
Query: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
R RER K++ ++ R E R RERER R RER+ +R RE +R R+++ +
Sbjct: 369 RDRERSSDRNKDRSRSREKSRDRERE-REREREREREREREREREREREREREREREREK 427
Query: 2146 DWDRNRE----------RSANRDREREA---DRGKEWD-RSRERSRNRERERDRRRDRDR 2191
D R+RE + + RE+EA +R K W+ R R+++R E+E +R +R R
Sbjct: 428 DKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRR 487
Query: 2192 SRSRERDRDKARDRERGRDRKDRSKSKESA 2221
++E R K + DR D + SA
Sbjct: 488 EMAKEAKRLKEFLEDYDDDRDDPKYYRGSA 517
Score = 58.9 bits (141), Expect = 5e-08
Identities = 38/98 (38%), Positives = 57/98 (58%), Gaps = 9/98 (9%)
Query: 2150 NRERSANRDRER--EADRGK-EWDRSRERSRNRERERDRRRDRDR-SRSRERDRDKARDR 2205
+RE S RD + E ++GK E +R RERER+R R+R+R R RER+R++ R++
Sbjct: 278 SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337
Query: 2206 ERGRDR-----KDRSKSKESARDPKPEASRASDAGTAS 2238
E+ R+R +DR ++KE RD E R D +S
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSS 375
Score = 42.4 bits (98), Expect = 0.005
Identities = 50/212 (23%), Positives = 86/212 (40%), Gaps = 45/212 (21%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDA--QGRASEDRRRERERGRNWSR--E 2126
RE + + + + E + + ++ E+ L E +A Q R RER++ R + + E
Sbjct: 421 REREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAE 480
Query: 2127 RDWDRPREW--DRHRDKDSSRDWDRNRE------------RSANRDREREADRGKEWDRS 2172
R+ +R RE + R K+ D+D +R+ R +R++E EAD E DR
Sbjct: 481 REEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD---ERDRK 537
Query: 2173 RERS---------------------RNRERERDRRRD---RDRSRSRERDRDKARDRERG 2208
RE+ + E+E +RRR + S E + +K E+
Sbjct: 538 REKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKR 597
Query: 2209 RDRKDRSKSKESARDPKPEASRASDAGTASQA 2240
+ + + E KP S A + S A
Sbjct: 598 EEPMEEEEEPEQKPCLKPTLRPISSAPSVSSA 629
Score = 38.1 bits (87), Expect = 0.098
Identities = 77/369 (20%), Positives = 132/369 (35%), Gaps = 84/369 (22%)
Query: 133 KERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERPLKGIQSRLRKK- 191
+ER E+ + D D + + D ++L+ +LR K + + LK + R RKK
Sbjct: 415 REREREREREREKDKKRDREEDEEDAYERRKLERKLREK--EAAYQERLKNWEIRERKKT 472
Query: 192 -------RREEGPAETVGSEA---SDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEGK 241
REE + EA + +E + +P+ +G Q DRE ++E
Sbjct: 473 REYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA- 531
Query: 242 AAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISE 301
DE D R K E E E
Sbjct: 532 ------DER--DRKREKEELE--------------------------------------E 545
Query: 302 ARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKSS 361
R RLL D P+ + +++ E +E Q + K P + E+K
Sbjct: 546 IRQRLLAEGHPD---PDAELQRMEQE--AERRRQPQIKQEPESEEEE--------EEKQE 592
Query: 362 EDQGIKGRIEKAANPSGKKKLK-IFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDC--I 418
+++ + +E+ P K LK +P+ AP S G A P++ + C I
Sbjct: 593 KEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGN-----ATPNTPGDESPCGII 647
Query: 419 LKHAAATMKFLSSGKEQKPKPKEKMKM-KPEKPSLPKCGAQAGIKISSVHKRPAPEKKET 477
+ H + + +E +PK +K+ P P + + + SV + E +
Sbjct: 648 IPHENSPDQ--QQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDD 705
Query: 478 TVKKAVVVP 486
+K +VP
Sbjct: 706 VPRKRKLVP 714
Score = 37.4 bits (85), Expect = 0.17
Identities = 49/229 (21%), Positives = 90/229 (39%), Gaps = 20/229 (8%)
Query: 720 RYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVM 779
R K K R + +D + R LRE+ A RLK E+ ++ + E+ A
Sbjct: 425 REKDKKRDREEDEEDAYERRKLERKLREK-EAAYQERLKNWEIRERKKTREYEKEAEREE 483
Query: 780 ESRTKLHNESKKTAPRQEAIPDLEDSPP----------VSDSEEQQESARAVPEKSTAPL 829
E R ++ E+K+ E D D P + D E++ E+ ++ L
Sbjct: 484 ERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEEL 543
Query: 830 LDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDS 889
++ +L + A L + + + P + EP ++++ K+E + + +
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEE---EEKQEKEEKREEP 600
Query: 890 SAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHP 938
+ P+ + P P ++S P + SAS P PGD P
Sbjct: 601 MEEEEEPEQKPCLKPTLRP-ISSAPSVSSAS-----GNATPNTPGDESP 643
Score = 31.6 bits (70), Expect = 9.2
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 2180 ERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASR 2230
E E D+R R S+ RD K + E+G+ K+R + ++ R+ + E R
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERER 318
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 114 bits (285), Expect = 1e-24
Identities = 81/233 (34%), Positives = 118/233 (50%), Gaps = 22/233 (9%)
Query: 2012 QGQAPQVMKPGPRPLL--ELPSHPPQHR-KDRWEEAGPPSALSSSAPGQG--PEADGQWA 2066
+G+ P++ + G R ++ SH D WE SS P + PE D +
Sbjct: 564 RGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETR-------SSYPERDRYPERDNRDQ 616
Query: 2067 SADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRE 2126
+ D + H R++ + R+R+ ++P QGR E R ER R R
Sbjct: 617 ARDSSFERRHGERDRR-DNRERD-------QRPSSPIRHQGRNDELERDERREERRVDRV 668
Query: 2127 RDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRR 2186
D R E R RD++ RD +R RER RDRERE +R E +R+RER R RE+ERDR
Sbjct: 669 DD--RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726
Query: 2187 RDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGTASQ 2239
RDRDR RER+R++ RDRE+ R+R+ + +E R+ + E R + A +
Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARE 779
Score = 101 bits (252), Expect = 7e-21
Identities = 63/149 (42%), Positives = 89/149 (59%), Gaps = 9/149 (6%)
Query: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
R+RER KE+ LE A+ R +R RE+ER R R+RD DR RE +R RD++ R
Sbjct: 693 RERERDREREKERELERERARER---EREREKERDRERDRDRDHDRERERERERDREKER 749
Query: 2146 DWDRN-RERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERD-RDKAR 2203
+ +R RER R+RERE +R +E +R+RER + RER+RD D+D+ R R+ R++ R
Sbjct: 750 EREREERERERERERERERERERERERARERDKERERQRD-WEDKDKGRDDRREKREEIR 808
Query: 2204 DRERGRDRKDRSKSKESARD---PKPEAS 2229
+ RD D KSK+ R+ P P S
Sbjct: 809 EDRNPRDGHDERKSKKRYRNEGSPSPRQS 837
Score = 79.7 bits (195), Expect = 3e-14
Identities = 74/226 (32%), Positives = 95/226 (42%), Gaps = 37/226 (16%)
Query: 2027 LELPSHPPQHRKDRWEEAGPPSALSSSAPGQGP----EADGQWASADFREGKGHEYRNQT 2082
L PS+ HR +++G L S + + E G+ S + +G R+ T
Sbjct: 1206 LRSPSNDSAHRSGD-DQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRS-T 1263
Query: 2083 FEGRQRERFDVGPKEKPLEEPDAQGRA----SEDRRRERER---GRNWSRERDWDRPREW 2135
RQ R + P + R+ S DR +ER+R R RER R REW
Sbjct: 1264 SSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREW 1323
Query: 2136 DRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSR 2195
DR DKD W RNR DR R R R RERERD+RRD DR R R
Sbjct: 1324 DRDADKD----WPRNR------------------DRDRLRERERERERDKRRDLDRERER 1361
Query: 2196 ERDRDKARDRERGRDRKDRSKSKESAR--DPKPEASRASDAGTASQ 2239
RDR+R RDR S ES + + K E D + S+
Sbjct: 1362 LISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSR 1407
Score = 65.9 bits (159), Expect = 4e-10
Identities = 50/169 (29%), Positives = 74/169 (43%), Gaps = 15/169 (8%)
Query: 2069 DFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASE---DRRRERERGRNW-S 2124
D K E + R+RER +E+ + + R E DR +ERER R
Sbjct: 698 DREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERE 757
Query: 2125 RERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERD 2184
RER+ +R RE R+ +R RER+ RD+ERE R E D+ + R RE+ +
Sbjct: 758 RERERERERE----------RERERERERARERDKERERQRDWE-DKDKGRDDRREKREE 806
Query: 2185 RRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
R DR+ + + K R R G +S + P +A + D
Sbjct: 807 IREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGD 855
Score = 59.3 bits (142), Expect = 4e-08
Identities = 44/127 (34%), Positives = 56/127 (44%), Gaps = 12/127 (9%)
Query: 2110 SEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEW 2169
S DRR ER R+R+ D E + +D+ SSRD +RE RDR D
Sbjct: 409 SHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDT---- 464
Query: 2170 DRSRERSRNRERERDRRRDRDRSRSRERDRD-----KARDRERGRDRKDRSKSKESARDP 2224
R R R+ RD R RD SR + RD RD RDR+ R ++ D
Sbjct: 465 -RDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKE--DT 521
Query: 2225 KPEASRA 2231
PE SR+
Sbjct: 522 YPEESRS 528
Score = 58.9 bits (141), Expect = 5e-08
Identities = 59/217 (27%), Positives = 100/217 (46%), Gaps = 20/217 (9%)
Query: 2037 RKDRWEEA--GPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVG 2094
RK R ++ G PS S+S+ Q + S+ + + H R+ +F+ R +R
Sbjct: 1247 RKSRIDQLKRGEPSR-STSSDRQDSRSHSSRRSSPESDRQVHS-RSGSFDSR--DRLQER 1302
Query: 2095 PKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRER- 2153
+ + E + + R + R +R+ ++W R RD DR RE +R R++D RD DR RER
Sbjct: 1303 DRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERL 1362
Query: 2154 ---------SANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDR-DKAR 2203
+RDR E+ + + R E E ERD S + +++R DK
Sbjct: 1363 ISDSVERDRDRDRDRTFESSQIESVKRC-EAKLEGEHERDLESTSRDSLALDKERMDKDL 1421
Query: 2204 DRERGRDRKDRSKSKES--ARDPKPEASRASDAGTAS 2238
+G + ++S+ ES A D + + A G+ +
Sbjct: 1422 GSVQGFEETNKSERTESLEAGDDESKLDDAHSLGSGA 1458
Score = 58.5 bits (140), Expect = 7e-08
Identities = 45/162 (27%), Positives = 73/162 (45%), Gaps = 17/162 (10%)
Query: 2085 GRQRERFDVGPKEKPLEEPDAQGRASEDRRRERER---------GRNWSRERDWDRPREW 2135
G +R P+ K P Q + RR R S R RE
Sbjct: 339 GSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREK 398
Query: 2136 DRHRDKDSSRDWDRNRERSAN----RDREREADRGKEWDRSRERSRNRERERDRRRDRDR 2191
RH + +S+ DR ER + RDRE+++ +E+++ + SR+ +R+ R RDR
Sbjct: 399 GRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDR 458
Query: 2192 SRSRE-RDRDK---ARDRERGRDRKDRSKSKESARDPKPEAS 2229
+R+ RDR + +RD R+ +D S+ + +RDP+ S
Sbjct: 459 RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRS 500
Score = 55.1 bits (131), Expect = 8e-07
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 11/163 (6%)
Query: 2069 DFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERD 2128
D + ++ + R+R+R +E+ E + + +R RERER R R+++
Sbjct: 724 DRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKE 783
Query: 2129 WDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRD 2188
+R R+W+ DKD RD DR +R R+ +R G + +S++R RN R
Sbjct: 784 RERQRDWE---DKDKGRD-DRREKREEIRE-DRNPRDGHDERKSKKRYRNEGSPSPR--- 835
Query: 2189 RDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRA 2231
+S R R+ D D K+ K + ++ +P+ SR+
Sbjct: 836 --QSPKRRREHSPDSDAYNSGDDKN-EKHRLLSQVVRPQESRS 875
Score = 54.7 bits (130), Expect = 1e-06
Identities = 57/213 (26%), Positives = 76/213 (35%), Gaps = 49/213 (23%)
Query: 2059 PEADGQWASADFREGKGH-EYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRER 2117
PE + RE E RN E R R ++ D GR+
Sbjct: 523 PEESRSYGRNHLREESSRTEIRN---ESRNESRSEI--------RNDRMGRSRGRVPELP 571
Query: 2118 ERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSR 2177
E+G SR D + D +R R+R RD +A R ER R
Sbjct: 572 EKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDR 631
Query: 2178 NRERERDRR----------------------------------RDRDRSRSRERDRDKAR 2203
RERD+R R R+R R RERDR++ R
Sbjct: 632 RDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERER 691
Query: 2204 DRERGRDR---KDRSKSKESARDPKPEASRASD 2233
+RER RDR K+R +E AR+ + E + D
Sbjct: 692 ERERERDREREKERELERERAREREREREKERD 724
Score = 44.7 bits (104), Expect = 0.001
Identities = 63/277 (22%), Positives = 114/277 (41%), Gaps = 36/277 (12%)
Query: 1238 EKKPSKYPLCSADAAVSTTPPGSPPPP--PPLPEPPVLKVLSSLKPAAPSPATAATTAAA 1295
E P + + A+ + T PGS P P LP PP + + A PAT A T AA
Sbjct: 1070 EDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATAT----ATTVPATLAATTAA 1125
Query: 1296 ASTAASSTASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDGVP 1355
A+T+ S++A + S +A+P T + + S R+ + + P T ED
Sbjct: 1126 AATSFSTSAITISTSATPTNTTNNTF-----ANEDSHRKCHRTRVEKVETPHVTIEDAQH 1180
Query: 1356 APPLLDPIVQQFGQFSKDKALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPE 1415
P+ ++ +++ R P + R+ D Q GR+ R
Sbjct: 1181 RKPMDQ---KRSSSLGSNRSNRSHTSGRLRSPSND-SAHRSGDDQ---SGRK----RVLH 1229
Query: 1416 AAAAEREEVAYDPEDETILEEAKVTVDDL----PNRMCADVRRNS---VERPAEPVAGAA 1468
+ + +RE+ + I E K +D L P+R + R++S R + P +
Sbjct: 1230 SGSRDREKT----KSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQ 1285
Query: 1469 TPS---LVEQQKMLEELNKQIEEQKRQLEEQEEALRQ 1502
S + + L+E ++ +++R+ E ++ R+
Sbjct: 1286 VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQRE 1322
Score = 41.6 bits (96), Expect = 0.009
Identities = 75/323 (23%), Positives = 117/323 (36%), Gaps = 73/323 (22%)
Query: 730 FNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNES 789
+N D KN+ HR+L + + + L P L WKE E R ES
Sbjct: 851 YNSGDDKNEK--HRLLSQVVRPQESRSLSPSHLTEDRQGRWKE-------EDRKPERKES 901
Query: 790 KKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSS-MLKDTTSQHRAHL 848
+ QE VS ++Q+E + E S D+ +D + RAH
Sbjct: 902 SRRYEEQEL------KEKVSSVDKQREQTEIL-ESSRMRAQDIIGHHQSEDRETSDRAH- 953
Query: 849 FDLNCK------------------ICTGQVPSAEDEP---APKKQKLSASVKKEDLKSKH 887
D N K I G + + ++ +PKK + S++K+ KSK
Sbjct: 954 -DENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKG 1012
Query: 888 DSSAPD--PAPDSADEVMPEAVPEVASEPGLESASHPN--------VDRTYFPGPPGDGH 937
DS D A S + P P E +E + N + T F +
Sbjct: 1013 DSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDV 1072
Query: 938 PE-------------------PSPLEDLSPCPASCGSGVVTTV--TVSGRDPRTAPSSSC 976
P+ PSPL L P P + TTV T++ A S S
Sbjct: 1073 PDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFST 1132
Query: 977 TA--VASAASRPDSTHMVEARQD 997
+A ++++A+ ++T+ A +D
Sbjct: 1133 SAITISTSATPTNTTNNTFANED 1155
Score = 38.5 bits (88), Expect = 0.075
Identities = 39/174 (22%), Positives = 67/174 (38%), Gaps = 33/174 (18%)
Query: 2092 DVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERD-WDRPREWD---RHRDKDSSRDW 2147
D+ +K E+ + R E R ++RGR++ R+R+ D+PR +H SSR
Sbjct: 273 DIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHH 332
Query: 2148 DRNRERSANRDREREADRGKEW----------------------------DRSRERSRNR 2179
+ + ++ R + R K R + R+R
Sbjct: 333 SSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHR 392
Query: 2180 ERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
R++ R S+ DR R RE R ++DR K R+ + + S + D
Sbjct: 393 SPMREKGRHDHERTSQSHDRRHER-REDTRGKRDREKDSREEREYEQDQSSSRD 445
Score = 37.0 bits (84), Expect = 0.22
Identities = 45/179 (25%), Positives = 69/179 (38%), Gaps = 19/179 (10%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEP-----DAQGRASEDRRRERERGRNWSR 2125
RE + E + R+RER +E+ E + + + +DRR +RE R
Sbjct: 753 REERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRN 812
Query: 2126 ERD-WDRPREWDRHRDKDS---SRDWDRNRERSANRDREREADRGKEWDR---------- 2171
RD D + R+R++ S + R RE S + D D E R
Sbjct: 813 PRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQE 872
Query: 2172 SRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASR 2230
SR S + E + R ++ R ER R E+ K S K+ + E+SR
Sbjct: 873 SRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSR 931
Score = 36.6 bits (83), Expect = 0.28
Identities = 41/184 (22%), Positives = 67/184 (36%), Gaps = 27/184 (14%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWD 2130
RE R + +E + + R D K + + E D R D R+ ++R RN
Sbjct: 778 RERDKERERQRDWEDKDKGRDDRREKREEIRE-DRNPRDGHDERKSKKRYRNEGSPSPRQ 836
Query: 2131 RPREWDRHR-DKDSSRDWDRNRER----------------SANRDREREADRGKEWDRSR 2173
P+ H D D+ D E+ S + E R KE DR
Sbjct: 837 SPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKP 896
Query: 2174 ERSRNRERERDRR---------RDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDP 2224
ER + R ++ + R+++ E R +A+D +DR S + +
Sbjct: 897 ERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDEN 956
Query: 2225 KPEA 2228
K +A
Sbjct: 957 KKKA 960
Score = 33.5 bits (75), Expect = 2.4
Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 2139 RDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERD 2198
R K S ++ R+ ER RER ++ ++ D ++ E R++ R R RE++
Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKE 125
Query: 2199 RDKARDRERGRDRKDRSKSKESARD 2223
D +ER + ++ + E+ RD
Sbjct: 126 -DIKITKERTPESEEENVEWETNRD 149
Score = 33.1 bits (74), Expect = 3.1
Identities = 48/239 (20%), Positives = 93/239 (38%), Gaps = 25/239 (10%)
Query: 1964 PQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGS-APFSEKNEQTPSRFHFQGQAPQVMKPG 2022
P+ D+R S R+ N+ +P+P Q R +P S+ + QV++P
Sbjct: 813 PRDGHDER-KSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQ 871
Query: 2023 PRPLLELPSHPPQHRKDRW-EEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQ 2081
L PSH + R+ RW EE P SS + E + +S D
Sbjct: 872 ESRSLS-PSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVD------------ 918
Query: 2082 TFEGRQRERFDVGPKEKPLEEPDAQGRASEDRR-RERERGRNWSRERDWDRPREWDRHRD 2140
+QRE+ ++ + + SEDR +R N + + +P + +
Sbjct: 919 ----KQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIK----KK 970
Query: 2141 KDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDR 2199
K+ +R + + D + + + + +S E+ R + + D + ++ ++ R
Sbjct: 971 KEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKR 1029
Score = 31.6 bits (70), Expect = 9.2
Identities = 40/162 (24%), Positives = 67/162 (41%), Gaps = 23/162 (14%)
Query: 2069 DFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERER--------- 2119
D R+ K YRN EG R PK + PD+ S D + E+ R
Sbjct: 818 DERKSK-KRYRN---EGSPSPR--QSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQ 871
Query: 2120 -GRNWSRER-DWDRPREW---DRHRD-KDSSRDWDRN--RERSANRDREREADRGKEWDR 2171
R+ S DR W DR + K+SSR ++ +E+ ++ D++RE E R
Sbjct: 872 ESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSR 931
Query: 2172 SRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKD 2213
R + + + R DR+ + + K + + + ++D
Sbjct: 932 MRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKED 973
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 110 bits (275), Expect = 2e-23
Identities = 63/162 (38%), Positives = 94/162 (58%), Gaps = 4/162 (2%)
Query: 2073 GKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRP 2132
G G +++ + RQRER V K + + D + R E RR+E+E RN RE+ +
Sbjct: 64 GLGQAHKDADGDDRQRERDRVREKTEKERDRDRK-RDRERRRKEKETNRNRDREKQTEIE 122
Query: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRS 2192
R+ +R + K R+ DR RER +RDRE+E +R E DR +R ERERDR R++ +
Sbjct: 123 RDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE 182
Query: 2193 RSRERDRDKARDRERGRDRK-DRSKSKESARDPKPEASRASD 2233
R ERDRD+ RD E+ R+R+ DR + ++ R + E R +D
Sbjct: 183 RETERDRDRQRDTEKERERQTDRERDRQ--RKTQTERQRETD 222
Score = 104 bits (260), Expect = 9e-22
Identities = 63/173 (36%), Positives = 91/173 (52%), Gaps = 17/173 (9%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASE-DRRRERERGRNWSRERDWDRP 2132
+ + QT R RER K+K E +GR E DR RE+ER R ++RD R
Sbjct: 111 RNRDREKQTEIERDRER----EKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRE 166
Query: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDR--- 2189
E +R RD++ + +R ER +R R+ E +R ++ DR R+R R + ER R DR
Sbjct: 167 TETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGE 226
Query: 2190 ---DRSRSRERDRDKARDRERGRDRKDRSKS------KESARDPKPEASRASD 2233
DR R R+RDRD+ ++R+R RDRK+ K K+ ++ K E R D
Sbjct: 227 RETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
Score = 104 bits (259), Expect = 1e-21
Identities = 54/153 (35%), Positives = 88/153 (57%), Gaps = 3/153 (1%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEP-DAQGRASEDRRRERERGRNWSRERDWDRP 2132
KG E R+R+R +E+ E+ D Q +R R+RER + RE + DR
Sbjct: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD 190
Query: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRS 2192
R+ D ++++ D +R+R+R +R+RE DR E +R +R R R+R+RDR ++RDR
Sbjct: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDR--EGERETDRRRERQRDRDRGKERDRE 248
Query: 2193 RSRERDRDKARDRERGRDRKDRSKSKESARDPK 2225
R R+ +R K R +ER ++RK++ K ++ D K
Sbjct: 249 RDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Score = 61.6 bits (148), Expect = 8e-09
Identities = 47/127 (37%), Positives = 68/127 (53%), Gaps = 31/127 (24%)
Query: 2119 RGRNWSRERDWDRPREW---DRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRER 2175
RGR S+E PR W H+D D DR+RE DR +E +ER
Sbjct: 51 RGRLGSQES----PRSWGLGQAHKDADGD-------------DRQRERDRVRE-KTEKER 92
Query: 2176 SRNRERERDRRRDRDRSRSRERDRDK----ARDRER----GRDR-KDRSKSKESARDPKP 2226
R+R+R+R+RRR +++ +R RDR+K RDRER GR+R +DR + +E RD +
Sbjct: 93 DRDRKRDRERRR-KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREK 151
Query: 2227 EASRASD 2233
E R ++
Sbjct: 152 ERERQTE 158
Score = 39.3 bits (90), Expect = 0.044
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 22/90 (24%)
Query: 2077 EYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWD 2136
E QT R R+R +++ E D +G DRRRER+R R+ +ERD +R R+ +
Sbjct: 198 ERERQTDRERDRQRKTQTERQR---ETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
Query: 2137 RHRDK-------------------DSSRDW 2147
R +++ D R W
Sbjct: 255 RKKERKKERKKERKEKKKEEKRREDKKRKW 284
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 110 bits (274), Expect = 2e-23
Identities = 65/182 (35%), Positives = 95/182 (52%), Gaps = 8/182 (4%)
Query: 2057 QGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRE 2116
+G E + + RE + R RER +EK E + Q R+RE
Sbjct: 13 RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREK---ERERQKERDRQRQRE 69
Query: 2117 RERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERS 2176
RE R R+R+ R RE R D++ +D DR R+R +R+RER G+E D+ ER
Sbjct: 70 RETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERE 129
Query: 2177 RNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKS-----KESARDPKPEASRA 2231
R+RERER R+R+R+R R RER R+ R+R+R +R++R K K+ ++ K E R
Sbjct: 130 RDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRR 189
Query: 2232 SD 2233
D
Sbjct: 190 ED 191
Score = 103 bits (258), Expect = 1e-21
Identities = 56/159 (35%), Positives = 92/159 (57%), Gaps = 5/159 (3%)
Query: 2077 EYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWD 2136
E + +T G++ ER +E+ + DR RER+R + +ER+ + R+
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQ 65
Query: 2137 RHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRER----SRNRERERDRRRDRDRS 2192
R R++++ R+ +R RER R+R+R+ DR ++ DR RER RNRER R R+RD+
Sbjct: 66 RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQ 125
Query: 2193 RSRERDRDKARDRERGRDR-KDRSKSKESARDPKPEASR 2230
RERDR++ R R+R R+R + R + +E+ R+ + A R
Sbjct: 126 TERERDRERERQRQRERERQRQRERKRETDRERQRWAER 164
Score = 101 bits (252), Expect = 7e-21
Identities = 62/158 (39%), Positives = 91/158 (57%), Gaps = 5/158 (3%)
Query: 2071 REGKGHEYRN-QTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERD 2128
R+ H R+ QT ++RER +++ E E + + +R+R+RER R RERD
Sbjct: 38 RQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERD 97
Query: 2129 WDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRD 2188
DR RE R R+ D +R+ +R R ++ ERE DR +E R RER R R+RER R D
Sbjct: 98 KDRDRE--RKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD 155
Query: 2189 RDRSRSRER-DRDKARDRERGRDRKDRSKSKESARDPK 2225
R+R R ER +R K R +ER ++RK++ K ++ D K
Sbjct: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKK 193
Score = 95.5 bits (236), Expect = 5e-19
Identities = 57/154 (37%), Positives = 85/154 (55%), Gaps = 9/154 (5%)
Query: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
R+R+R KE E + R ++ R R R R+ RERD RE +R R K+ R
Sbjct: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE--R 62
Query: 2146 DWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRE------RDR 2199
D R RER R+ ER+ +R ++ +R R+ R R+++RDR R R+ R+RE R+R
Sbjct: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
Query: 2200 DKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
DK +RER R+R +R + +E R + E R +D
Sbjct: 123 DKQTERERDRER-ERQRQRERERQRQRERKRETD 155
Score = 89.7 bits (221), Expect = 3e-17
Identities = 48/129 (37%), Positives = 73/129 (56%), Gaps = 16/129 (12%)
Query: 2121 RNWSRERDWDRPREWDRHRDKDSSRD-----------WDRNRERSANRDREREADRGKEW 2169
R R+R+ DR +E +R RD+ R+ DR+RER DRE+E +R KE
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 2170 DRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRK-----DRSKSKESARDP 2224
DR R+R R ERE +R+R+R R R R+R D+ RD++R R+RK +R ++++ R+
Sbjct: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
Query: 2225 KPEASRASD 2233
+ R D
Sbjct: 123 DKQTERERD 131
Score = 78.6 bits (192), Expect = 7e-14
Identities = 44/109 (40%), Positives = 65/109 (59%), Gaps = 8/109 (7%)
Query: 2130 DRPREWDRHRD--KDSSRDWDRNRERSANRDRE---READRGKEWDRSRERSRNRERERD 2184
+R RE R D K++ R+ DR RER +RE R+ DR +E DR +R + RER+++
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 2185 RRRDRDRSRSRERDRDKARDRERGRDRK---DRSKSKESARDPKPEASR 2230
R R R R R ER+ ++ R+R+R R+RK DR + K+ R+ K E R
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR 110
Score = 50.4 bits (119), Expect = 2e-05
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPR 2133
+ E + +T R+R R ++K E R R+RER R RER+ R R
Sbjct: 100 RDRERKRETDRNRERNRKGGRERDKQTE-----------RERDRERERQRQRERERQRQR 148
Query: 2134 EWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRR 2187
E R D++ R W ER R +ER+ +R +E+ + +R D++R
Sbjct: 149 ERKRETDRERQR-WAEREERKKERKKERKKER-------KEKKKEEKRREDKKR 194
Score = 50.1 bits (118), Expect = 2e-05
Identities = 30/77 (38%), Positives = 44/77 (57%), Gaps = 4/77 (5%)
Query: 2167 KEWDRSRERSRNRERERDRRRDRDRSRSRERD-RDKARDRERGRDRK-DRSKSKE--SAR 2222
++ +R RE R +E ER+R R R+R ER+ R + RDR R RDR+ DR K +E R
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKER 62
Query: 2223 DPKPEASRASDAGTASQ 2239
D + + R ++ T Q
Sbjct: 63 DRQRQRERETERETERQ 79
Score = 47.4 bits (111), Expect = 2e-04
Identities = 20/60 (33%), Positives = 35/60 (58%)
Query: 2174 ERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
ER R R+RE DR ++ +R R R+R+R+ +RE ++DR + ++ D + E R +
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 107 bits (268), Expect = 1e-22
Identities = 65/170 (38%), Positives = 97/170 (57%), Gaps = 7/170 (4%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWD 2130
RE + R++ ++RER K + E D + +R+RERER R +R+R+ +
Sbjct: 262 RERERDRDRDRDRRQKERER-QTDRKRQRRTERDRETERKRERQRERERERERNRKRERE 320
Query: 2131 RPREWDRHRDKDSSRDWDRNRERSANR----DREREADRGKEWDRSRERSRNRERERDRR 2186
R RE +R R +++ RD ++ RER R DRER G+E R ER R RERERDR+
Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQ 380
Query: 2187 RDRDR-SRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAG 2235
R+R R R+RDRD+ ++RER + KDR +E+ + + E R S+ G
Sbjct: 381 SAREREERERDRDRDRQKERER-QTEKDRDGQRETEKQREREKDRESERG 429
Score = 105 bits (262), Expect = 5e-22
Identities = 68/191 (35%), Positives = 103/191 (53%), Gaps = 23/191 (12%)
Query: 2041 WEEAGPPSALSSSAPG--QGPEADG-----QWASADFREGKGHEYRNQTFEGRQRERFDV 2093
W E P S PG + P G + A D RE + R + E RQ ER
Sbjct: 17 WVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD 76
Query: 2094 GPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRER 2153
+E+ R +DR R+R+R R R+R+ +R R+ DR RD+ R+ +RNR++
Sbjct: 77 RKRER---------RREKDRHRKRDRHRERQRDREKERERQTDRERDR--QREKERNRQK 125
Query: 2154 SANRDREREADRGK----EWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGR 2209
R+ ERE +RG+ + R RER R+ E+ER+R+ DR+R R ER+R K R+RE+ R
Sbjct: 126 ERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNR 185
Query: 2210 -DRKDRSKSKE 2219
+R++R + +E
Sbjct: 186 QERRERERQRE 196
Score = 102 bits (253), Expect = 6e-21
Identities = 63/172 (36%), Positives = 95/172 (55%), Gaps = 20/172 (11%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERE------RGRNWSRER 2127
K E E R+RER +EK + D +R RERE R R RER
Sbjct: 177 KEREREKNRQERRERER----QREKENKTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 2128 DWDRPREWDRHR--------DKDSSRDWDRNRERSANRDRE-READRGKEWDRSRERSRN 2178
D R E +R + ++++ RD +R RER +RDR+ R+ +R ++ DR R+R
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 2179 RERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASR 2230
R+RE +R+R+R R R RER+R++ R+RER R+R +R + +E+ RD + E R
Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERER-ERERQRETERDREKERER 343
Score = 101 bits (251), Expect = 9e-21
Identities = 65/195 (33%), Positives = 94/195 (48%), Gaps = 32/195 (16%)
Query: 2077 EYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASE-DRRRERERGRNWSRER-DWDRPRE 2134
E + QT R R+R +EK E A R +E D+ RERER R+ R+R +R R+
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 2135 WDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRD---- 2190
DR R + + RD + R+R R+RERE +R ++ +R RER R RER+R+ RDR+
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
Query: 2191 --------------------------RSRSRERDRDKARDRERGRDRKDRSKSKESARDP 2224
R R RER+RD+ RER +DR + ++ R+
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER 402
Query: 2225 KPEASRASDAGTASQ 2239
+ E R T Q
Sbjct: 403 QTEKDRDGQRETEKQ 417
Score = 100 bits (250), Expect = 1e-20
Identities = 58/164 (35%), Positives = 94/164 (57%), Gaps = 5/164 (3%)
Query: 2072 EGKGHEYRNQTFEG-RQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDW 2129
E +G R++ +G R+RER KE+ + + + Q + +R++ERER +N R+
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
Query: 2130 DRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDR 2189
+R RE + +K R +R RER R+ E E +R ++ DR R+R R ERER+++ +R
Sbjct: 192 ERQREKE---NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAER 248
Query: 2190 DRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
+R+ RE +RDK R+RER RDR + KE R + R ++
Sbjct: 249 ERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Score = 100 bits (250), Expect = 1e-20
Identities = 60/178 (33%), Positives = 100/178 (56%), Gaps = 9/178 (5%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLE---EPDAQGRASEDRRRERERGRNWSRER 2127
R+ + R + E + +R +E+ E E + + + DR R+R+R RE+
Sbjct: 185 RQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREK 244
Query: 2128 DWDRPREWDRH--RDKDSSRDWDRNRERS-ANRDREREADRGKE--WDRSRERSRNRERE 2182
+R R +R RDK+ R+ DR+R+R ++RER+ DR ++ +R RE R RER+
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 2183 RDRRRDRDRSRSRERDRDKARDRERGRD-RKDRSKSKESARDPKPEASRASDAGTASQ 2239
R+R R+R+R+R RER+R++ R+RER R+ +DR K +E R + E R + T +
Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362
Score = 98.2 bits (243), Expect = 8e-20
Identities = 68/194 (35%), Positives = 100/194 (51%), Gaps = 21/194 (10%)
Query: 2056 GQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRR 2115
G+ + DGQ R+ + E QT RQR+ KE+ E+ + Q R +R+R
Sbjct: 138 GRDRQTDGQRERERQRDAE-KERERQTDRERQRQTERNRQKEREREK-NRQERRERERQR 195
Query: 2116 ERE---------RGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRG 2166
E+E RGR RER+ + E R D++ R RER +RER ++R
Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
Query: 2167 KEWDRSRERSRNRERERDRRR-------DRDRSRSRERDRDKARDRERGRDR---KDRSK 2216
E D+ RER R+R+R+RDRR+ DR R R ERDR+ R RER R+R ++R++
Sbjct: 256 TERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNR 315
Query: 2217 SKESARDPKPEASR 2230
+E R+ + E R
Sbjct: 316 KRERERERERERER 329
Score = 95.9 bits (237), Expect = 4e-19
Identities = 56/166 (33%), Positives = 88/166 (53%), Gaps = 9/166 (5%)
Query: 2077 EYRNQTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDWDRPREW 2135
E QT R R+R ++K E E + +G DR+ + +R R R+ + +R R+
Sbjct: 104 ERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163
Query: 2136 DRHRDKDSSRDWDRNRERSANRDREREADRGKE-----WDRSRERSRNRERERDRRRDRD 2190
DR R + + R+ + RER NR RE +R +E DR ER R RERER+ + +
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE 223
Query: 2191 RSRSRERDRDKARDRERGRDR---KDRSKSKESARDPKPEASRASD 2233
R R +R+RD+ R ER R++ ++R+ +E+ RD + E R D
Sbjct: 224 RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Score = 95.1 bits (235), Expect = 7e-19
Identities = 59/175 (33%), Positives = 92/175 (52%), Gaps = 17/175 (9%)
Query: 2079 RNQTFEGRQRERFDVGPKEKPLEEPDAQGRASE-DRRRERERGRNWSRERDWDRPR---- 2133
+ +T R+ ER +E+ E + R E +R RERER R R+R+ +R R
Sbjct: 288 QRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
Query: 2134 --EWDRHRDKDSSRDWDRNRERSANRDRER---------EADRGKEWDRSRERSRNRERE 2182
E DR R++ + R+ R ER R+RER E +R ++ DR +ER R E++
Sbjct: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Query: 2183 RDRRRDRDRSRSRERDRDKARDRERGRDR-KDRSKSKESARDPKPEASRASDAGT 2236
RD +R+ ++ R RE+DR+ R RERGR+R K + + ++ R +A R T
Sbjct: 408 RDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST 462
Score = 88.6 bits (218), Expect = 6e-17
Identities = 62/176 (35%), Positives = 95/176 (53%), Gaps = 21/176 (11%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRR---ERERGRNWSRE- 2126
RE + RN+ E R+RER +++ E + R + +R+ +RER R RE
Sbjct: 305 RERERERERNRKRE-RERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG 363
Query: 2127 -RDWDRPREWDRHRDKDSSRDW-----DRNRERSANRDREREADRGKEWDRSRERSRNRE 2180
R +R RE +R RD+ S+R+ DR+R+R R+R+ E DR D RE + RE
Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDR----DGQRETEKQRE 419
Query: 2181 RERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESAR-----DPKPEASRA 2231
RE+DR +R R R RER++ K R+R+R R + DR ++ R +P P +R+
Sbjct: 420 REKDRESERGRERGREREKQKGRERDRER-QTDRQAGRQRKRSTLYVNPPPRTARS 474
Score = 86.3 bits (212), Expect = 3e-16
Identities = 55/176 (31%), Positives = 88/176 (50%), Gaps = 22/176 (12%)
Query: 2077 EYRNQTFEGRQRERFDVGPKEKPLE-----EPDAQGRASEDRRRERERGRNWS------- 2124
E + +T R++ER ++ ++ + +GR +R RERER R+
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 2125 RERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERD 2184
RERD DR R+ +R R + RD R E+ R+++RE++RG+E R RE+ + RER+R+
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRE 447
Query: 2185 RRRDRDRSRSRERD----RDKARDRERGRDRKDRSKS------KESARDPKPEASR 2230
R+ DR R R+R R G + D ++ K S DPK ++R
Sbjct: 448 RQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTR 503
Score = 33.5 bits (75), Expect = 2.4
Identities = 54/235 (22%), Positives = 86/235 (36%), Gaps = 18/235 (7%)
Query: 30 RRTTIAKREGAGDAEADPLEPPPPQQQLGLSLRRSGRQPKRTERVEQFLTIARRRGR-RS 88
+R +RE D E Q++ R R+ + +R ++ T R R R
Sbjct: 152 QRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
Query: 89 MPVSLEDSGEPTSCPATDAETASEGSVESASETRSGPQSASTAVKERPASSEKVKGGDDH 148
E E TD E + E E ++ + AS ER E+ + D
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRD 271
Query: 149 DDTSDSDSDGLTLKELQNRLRRKREQEPTERPLKGIQSRLRKKRREEGPAETVGSEASDT 208
D KE + + RKR Q TER + + R R++ RE E
Sbjct: 272 RDRRQ--------KERERQTDRKR-QRRTERDRETERKRERQRERERERERNRKRERERE 322
Query: 209 VEGVLPSKQEPENDQGVVSQAGKDDRESKLEGKAAQD-IKDEEPGDLGRPKPECE 262
E ++E E D+ + +RE K + + D ++ + G GR + E E
Sbjct: 323 RERERERQRETERDR-------EKERERKRKRQTEMDRERNRQTGREGRRQAERE 370
>gi|47271475 SPOC domain containing 1 [Homo sapiens]
Length = 1216
Score = 107 bits (267), Expect = 1e-22
Identities = 98/361 (27%), Positives = 157/361 (43%), Gaps = 60/361 (16%)
Query: 596 KRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVP--------SVP 647
KRP + G + + P+P+ TA G + P P P
Sbjct: 523 KRPMVQ-----GPAGCQVFQPSPSGGTAGDP---------GGLSDPFYPPRSGSLALGDP 568
Query: 648 MASPAPGRLGAMSAA----PSQPNSQ-------------IRQNIRRSLKEILWKRVNDSD 690
+ PA + G M A P QP +R + RS++E+LW R+ +
Sbjct: 569 SSDPACSQSGPMEAEEDSLPEQPEDSAQLQQEKPSLYIGVRGTVVRSMQEVLWTRLRELP 628
Query: 691 DLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEIS 750
D +++E V IA IE +++L Q T+ RYK+KYRS++FNL+DP+N LF +V+ +++
Sbjct: 629 DPVLSEEVVEGIAAGIEAALWDLTQGTNGRYKTKYRSLLFNLRDPRNLDLFLKVVHGDVT 688
Query: 751 LAKLVRLKPEELVSKELSTWK---ERPARSVMESRTK---LHNESKKTAPRQEAIP-DLE 803
LVR+ +L +EL+ W+ E+ +++E + K SK T + I D++
Sbjct: 689 PYDLVRMSSMQLAPQELARWRDQEEKRGLNIIEQQQKEPCRLPASKMTHKGEVEIQRDMD 748
Query: 804 DSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSA 863
+ + D Q P+ P+ +DTT QH H D NC IC PS
Sbjct: 749 QTLTLEDLVGPQMFMDCSPQ--ALPIAS------EDTTGQHDHHFLDPNCHICKDWEPSN 800
Query: 864 EDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPD--SADEVMPEAVPEVASEPGLESASH 921
E + + K +++ K S P PAP+ E+ P + GL +
Sbjct: 801 ELLGSFEAAKSCG----DNIFQKALSQTPMPAPEMPKTRELSPTEPQDRVPPSGLHVPAA 856
Query: 922 P 922
P
Sbjct: 857 P 857
Score = 73.6 bits (179), Expect = 2e-12
Identities = 54/180 (30%), Positives = 87/180 (48%), Gaps = 16/180 (8%)
Query: 1010 KSILAKPSSSPDPRYLSVPPSPNISTSE--SRSPPEG-----DTTLFLSRLSTIWKGFIN 1062
K++ P +P+ +P + +S +E R PP G T L L W+G ++
Sbjct: 819 KALSQTPMPAPE-----MPKTRELSPTEPQDRVPPSGLHVPAAPTKALPCLPP-WEGVLD 872
Query: 1063 MQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRF 1122
M S+ +F +A VSG L + LP I G I VWD + + + +K++C++R
Sbjct: 873 MFSIKRFRARAQLVSGHSCRLVQALPTVIRSAGCIPSNIVWDLLASICPAKAKDVCVVRL 932
Query: 1123 HPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGL 1182
P + LYSY + R R G+ + + + L+PL A P+P++L P GPGL
Sbjct: 933 CPHGARDTQNCRLLYSYLNDRQRHGLASVEH---MGMVLLPLPAFQPLPTRLRPLGGPGL 989
Score = 40.8 bits (94), Expect = 0.015
Identities = 95/413 (23%), Positives = 142/413 (34%), Gaps = 91/413 (22%)
Query: 1549 PPASQASNHRDP------RQARRLAA--ETGEGEGEPLSRLSARGAQGAL----PERDAS 1596
PP ++ DP ++ RR A E EG G+ L + L P + A
Sbjct: 189 PPGRPLTSSPDPVPVRVRKKWRRQGAHSECEEGAGDFLWLDQSPRGDNLLSVGDPPQVAD 248
Query: 1597 RGGLVGQAPMPVPEEKEPA-SSPWASGEKPPAGSEQDGWKAEPGEGTRPATVGDSSARPA 1655
L G P P++ P SG +G+E+ G+ G+G +P +
Sbjct: 249 LESLGGPCRPPSPKDTGSGPGEPGGSGAGCASGTEKFGYLPATGDGPQPGS--------- 299
Query: 1656 RRVLLPTPPCGALQPGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRSSSP 1715
PCG + GFP+ GE +L SA P++ +S+
Sbjct: 300 --------PCGPV--GFPVPSGGE--------------SLSSAAQAPPQSAALCLGASAQ 335
Query: 1716 AGETEGDREPQARPG--EGTAPLPPPGQKVGGSQPPFQGQREPGPHALG---------MS 1764
A + + R G EG AP + +QP +G+ E G A +
Sbjct: 336 ASAEQQEAVCVVRTGSDEGQAPAQDQEELEAKAQPASRGRLEQGLAAPADTCASSREPLG 395
Query: 1765 GLHGP-NFPGPRGPAPPFPEENIASNDGPRGPPPARFGAQKGPIPSLFSGQHGPPPYGDS 1823
GL + R + PF E+ + +KGP+P G
Sbjct: 396 GLSSSLDTEASRACSGPFMEQRRSKGTK---------NLKKGPVPC-------AQDRGTD 439
Query: 1824 RGPSPSYLGGPRGVAPS---QFEERKDPHGEKR--EFQDAPYNEVTGAPAQFEGTEQAP- 1877
R S+ P +P + EE K PHG K P ++ GA + + Q P
Sbjct: 440 RSSDNSHQDRPEEPSPGGCPRLEEVKIPHGVKLVCYLGSGPVIQLLGAISHGQAGGQLPP 499
Query: 1878 -------FLGSRGGAPFQFGGQRRPLLSQLKGPRGGP--PPSQFGGQRGPPPG 1921
+ +P Q RR ++GP G PS GG G P G
Sbjct: 500 KLEVLEDLMEVSSPSPAQ--RLRRKKRPMVQGPAGCQVFQPSPSGGTAGDPGG 550
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 105 bits (263), Expect = 4e-22
Identities = 63/173 (36%), Positives = 91/173 (52%), Gaps = 15/173 (8%)
Query: 2072 EGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDR 2131
EG+ +T + ++ R + + +E + R SE R R+R+R RN R+RD +R
Sbjct: 6 EGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSE-RDRQRDRERNRERDRDRER 64
Query: 2132 PREWDRH--RDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDR 2189
++ DR R ++ RD DR RE RD+ERE DR E DR R++ + RE ER R R+R
Sbjct: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRER 124
Query: 2190 ------------DRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASR 2230
DR RER+R R+RE GR+RK + +E R+ K E R
Sbjct: 125 EKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERER 177
Score = 100 bits (250), Expect = 1e-20
Identities = 61/177 (34%), Positives = 93/177 (52%), Gaps = 10/177 (5%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDW 2129
+E K + ++ R RER +++ E + D +G +R R+R+R R RERD
Sbjct: 35 KESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERD- 93
Query: 2130 DRPREWDRHRDKDSSRDWDRNRERSANRDREREAD----RGKEWDRSRERSRNRERERDR 2185
+ RE DRH + D R + RE RDRERE R ++ DR +R R R+ ER+R
Sbjct: 94 -KERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERER 152
Query: 2186 RRDRDRS---RSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGTASQ 2239
R+R R RER+R++ R+RER R+ K+R + + R+ + E R D S+
Sbjct: 153 ETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESE 209
Score = 92.0 bits (227), Expect = 6e-18
Identities = 55/144 (38%), Positives = 82/144 (56%), Gaps = 10/144 (6%)
Query: 2086 RQRERFDVGPKEKPLE-----EPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRD 2140
RQRER +++ E E + DR R++++ R R RD +R ++ + R+
Sbjct: 74 RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRE 133
Query: 2141 KDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRD 2200
+ + R+ DR RER A R+RE +R E DR RER R R+RER+R+R+ ++ RER D
Sbjct: 134 RQTDRETDRERERQAERERETGRERKTE-DRHRERERERKRERERKRE---TKERERHTD 189
Query: 2201 KARDRERGRDRK-DRSKSKESARD 2223
R+R+R DRK DR + E RD
Sbjct: 190 MERERQRETDRKRDRQRESERERD 213
Score = 44.7 bits (104), Expect = 0.001
Identities = 31/92 (33%), Positives = 45/92 (48%), Gaps = 11/92 (11%)
Query: 2075 GHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRE--RERGRNWSRERDWDRP 2132
G E + R+RER + E + R +EDR RE RER R R+R+
Sbjct: 131 GRERQTDRETDRERER------QAERERETGRERKTEDRHRERERERKRERERKRE---T 181
Query: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREAD 2164
+E +RH D + R + +R+R R+ ERE D
Sbjct: 182 KERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 36.2 bits (82), Expect = 0.37
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 17/79 (21%)
Query: 2172 SRERSRNRERERDRR-RDRDRSRSRERDRDKA---------------RDRERGRDR-KDR 2214
S+ R+ E + R R+R R +R+RD+A RDRER R+R +DR
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDR 62
Query: 2215 SKSKESARDPKPEASRASD 2233
+ K++ R+ + + R D
Sbjct: 63 EREKQTDREGERQRERERD 81
Score = 32.0 bits (71), Expect = 7.0
Identities = 31/133 (23%), Positives = 53/133 (39%), Gaps = 4/133 (3%)
Query: 1372 KDKALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDE 1431
+D+A E + +DR + + + D ER + +R R E + E E D + E
Sbjct: 31 RDRAKESKTEDRHSERDRQRDRERNRER---DRDREREKQTDREGERQRERERDRDRQRE 87
Query: 1432 TILEEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKR 1491
T E K D + R+ ER E V E + + + E++R
Sbjct: 88 TERERDKERETDRHTETDRE-RQKQKEREMERVRDREREKQKEMGRERQTDRETDRERER 146
Query: 1492 QLEEQEEALRQQR 1504
Q E + E R+++
Sbjct: 147 QAERERETGRERK 159
>gi|119226260 calcium homeostasis endoplasmic reticulum protein [Homo
sapiens]
Length = 916
Score = 105 bits (263), Expect = 4e-22
Identities = 146/545 (26%), Positives = 206/545 (37%), Gaps = 103/545 (18%)
Query: 1725 PQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEE 1784
P P AP PP + S+PP Q A G G+ P GPRGP P +
Sbjct: 358 PAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEAPG--GVQDPAAAGPRGPGP---HD 412
Query: 1785 NIASNDGP---RGPPPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQ 1841
I N P + P A +G Q+ P + G PP+ S + G
Sbjct: 413 QIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSHEGMWG-------- 464
Query: 1842 FEERKDPHGEKREFQDAPYNEVTGAP--AQFEGT-----EQAPFLGSRGGAPFQFGGQ-- 1892
E+R DP + +DAP+N A +QFEG EQ P+ G + PF+
Sbjct: 465 -EQRGDPGWNGQ--RDAPWNNQPDAAWNSQFEGPWNSQHEQPPWGGGQREPPFRMQRPPH 521
Query: 1893 -RRPLLSQLKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQ 1951
R P + P+ PP R PP F+ P FE R P+P++F+ P+G
Sbjct: 522 FRGPFPPHQQHPQFNQPPHPHNFNRFPP--RFMQDDFPPRHPFE--RPPYPHRFDYPQGD 577
Query: 1952 APNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFG----GLRGSAPFSEKNEQTPS 2007
P M P + ++ P + + P FG G G P + Q P
Sbjct: 578 FPAEMGPPHHHPGHRMPHPGINEHPPWAGPQHP---DFGPPPHGFNGQPPHMRR--QGPP 632
Query: 2008 RFHFQGQAPQVMKPGP---------RPLLELPSHP--PQHRKD-RWEEAGPPSALSSSAP 2055
H P ++ P PL++L H P KD R PPS +A
Sbjct: 633 --HINHDDPSLVPNVPYFDLPAGLMAPLVKLEDHEYKPLDPKDIRLPPPMPPSERLLAAV 690
Query: 2056 G---QGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASED 2112
P D S + + +E+ R+R+ +EK P S
Sbjct: 691 EAFYSPPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKG-----QEKRNSGP------SRS 739
Query: 2113 RRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRS 2172
R R + RGR+ SR R SS + R+R RS +R + RS
Sbjct: 740 RSRSKSRGRSSSRSNS----------RSSKSSGSYSRSRSRSCSRS----------YSRS 779
Query: 2173 RERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRAS 2232
R RSR+R R RSRSR + R +++ GR R+ RS+S P P +S
Sbjct: 780 RSRSRSRSRS-------SRSRSRSQSRSRSKSYSPGRRRRSRSRS------PTPPSSAGL 826
Query: 2233 DAGTA 2237
+ +A
Sbjct: 827 GSNSA 831
Score = 46.2 bits (108), Expect = 4e-04
Identities = 93/390 (23%), Positives = 132/390 (33%), Gaps = 97/390 (24%)
Query: 1476 QKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGVSMAHFSVSDALMSPPPKSSLPKAELF 1535
Q+ ++ L Q EE L +Q++ +QQ+ + + V +PPP + P
Sbjct: 311 QQQIQTLKTQHEEFVTSLAQQQQQQQQQQQQLQMPQMEAEVK---ATPPPPAPPP----- 362
Query: 1536 QQEQQSADKPA-SLPPASQASNHRDPRQARRLAAETGEGEGEPLSRLSARGAQGALPERD 1594
A PA ++PP +Q + + P Q G E E A G + +D
Sbjct: 363 ------APAPAPAIPPTTQPDDSKPPIQM------PGSSEYE---------APGGV--QD 399
Query: 1595 ASRGGLVGQAPM-PVPEEKEP------ASSPWAS---GEKPPAGSEQDG-WKAEPGEGTR 1643
+ G G P +P K P +PW E+PP Q G P +
Sbjct: 400 PAAAGPRGPGPHDQIPPNKPPWFDQPHPVAPWGQQQPPEQPPYPHHQGGPPHCPPWNNSH 459
Query: 1644 PATVGDSSARPARRVLLPTPPCGALQPGFPLQHDGERDPFTCPGFASQDKALGSAQYEDP 1703
G+ P +G+RD + +Q A ++Q+E P
Sbjct: 460 EGMWGEQRGDPG--------------------WNGQRD----APWNNQPDAAWNSQFEGP 495
Query: 1704 RNLHSAGRSSSPAGETEGDREP---QARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHA 1760
N + P G G REP RP P PP Q +QPP PH
Sbjct: 496 WN---SQHEQPPWG--GGQREPPFRMQRPPHFRGPFPPHQQHPQFNQPPH-------PHN 543
Query: 1761 LGMSGLHGPNFPGPRGPAPPFPEENIASNDGPRGPPPARFGAQKGPIPSLFSGQHGPPPY 1820
FP PR FP + R P P RF +G P+ H P +
Sbjct: 544 FN-------RFP-PRFMQDDFPPR----HPFERPPYPHRFDYPQGDFPAEMGPPHHHPGH 591
Query: 1821 GDSRGPSPSYLGGPRGVAPSQFEERKDPHG 1850
R P P P P + PHG
Sbjct: 592 ---RMPHPGINEHPPWAGPQHPDFGPPPHG 618
Score = 33.5 bits (75), Expect = 2.4
Identities = 41/191 (21%), Positives = 68/191 (35%), Gaps = 17/191 (8%)
Query: 1236 QSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEP--PVLKVLSSLKPAAPSPATAATTA 1293
Q +++ + + +A V TPP PPP P P P P KP P ++ A
Sbjct: 334 QQQQQQQQLQMPQMEAEVKATPPPPAPPPAPAPAPAIPPTTQPDDSKPPIQMPGSSEYEA 393
Query: 1294 AAASTAASSTASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDG 1353
A++ + P + I K FD P P++P G
Sbjct: 394 PG---GVQDPAAAGPRGPGPHDQIPP---NKPPWFDQPHPVAPWGQQQPPEQPPYPHHQG 447
Query: 1354 VP--APPLLDPIVQQFGQFSKDKALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVE 1411
P PP + +G+ D + D P++ + P+ A+++Q G +
Sbjct: 448 GPPHCPPWNNSHEGMWGEQRGDPGWNGQR-DAPWNNQ----PDAAWNSQF--EGPWNSQH 500
Query: 1412 RAPEAAAAERE 1422
P +RE
Sbjct: 501 EQPPWGGGQRE 511
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 102 bits (253), Expect = 6e-21
Identities = 120/413 (29%), Positives = 156/413 (37%), Gaps = 73/413 (17%)
Query: 1591 PERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAGSEQDGWKAEPGEGTRPATVGDS 1650
P+ +GG Q P P P + + PP G + PG+ P GD
Sbjct: 57 PQGPPPQGGNQPQGPPPPPGKPQGP---------PPQGGNKPQGPPPPGKPQGPPPQGDK 107
Query: 1651 SARPARRVLLPT--PPCGALQPGFPLQHDGE-RDPFTCPGFASQDKAL-GSAQYEDPRNL 1706
S P P PP G QP P G+ + P G Q G Q P+
Sbjct: 108 SRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 167
Query: 1707 HSAGRSSSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGL 1766
+ + S SP G+ +G P + P PPPG+ G PP QG +P
Sbjct: 168 NKSRSSRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQG---PPPQGGNKP---------- 212
Query: 1767 HGPNFPG-PRGPAPPFPEENIASNDGP---RGPPPARFGAQKGPIPSLFSGQHGPPPYGD 1822
GP PG P+GP P ++ ++ P +GPPP +GP P Q GPPP G
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-GPPPQGG 271
Query: 1823 SRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAPYNEVTGAPAQFEGTEQA--PFLG 1880
++ P G P+G P G K +P + G P Q Q P G
Sbjct: 272 NKPQGPPPPGKPQGPPPQ--------GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323
Query: 1881 SRGGAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETARGP 1940
G P Q G + P+G PPP G +GPPP S+ +AR P
Sbjct: 324 KPQGPPPQGGNK----------PQGPPPP---GKPQGPPP--------QGGSKSRSARSP 362
Query: 1941 HPNQFEGP---RGQAPNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFG 1990
P + +GP G P P P G PQQ +PP Q P P Q G
Sbjct: 363 -PGKPQGPPQQEGNNPQGPPPPAGGNPQQ-----PQAPPAGQPQGPPRPPQGG 409
Score = 92.0 bits (227), Expect = 6e-18
Identities = 113/390 (28%), Positives = 149/390 (38%), Gaps = 51/390 (13%)
Query: 1698 AQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPG 1757
+Q E P + + + P G + + P + PG+ P P G + G PP + G
Sbjct: 24 SQEESPSLIAGNPQGAPPQGGNK-PQGPPSPPGKPQGPPPQGGNQPQGPPPP--PGKPQG 80
Query: 1758 PHALGMSGLHGPNFPG-PRGPAPPFPEENIASNDGPRGPPPARFGAQKGPIPSLFSGQHG 1816
P G + GP PG P+GP P + PR PP G +GP P + G
Sbjct: 81 PPPQGGNKPQGPPPPGKPQGPPPQGDKSR-----SPRSPP----GKPQGPPPQGGNQPQG 131
Query: 1817 -PPPYGDSRGPSPSYLGGPRGVAPSQFEERKDPHGE-KREFQDAPYNEVTGAPAQFEGTE 1874
PPP G +GP P P+G P + P G+ K +P + G P Q
Sbjct: 132 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP 191
Query: 1875 QA--PFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPPP----------SQFGGQRGPPPGH 1922
Q P G G P Q G +P G GPPP S G +GPPP
Sbjct: 192 QGPPPPPGKPQGPPPQ--GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG 249
Query: 1923 FVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPG-PRGIQPQQFEDQR-VHSPPRFTN 1980
P+GP P + +GP P P+G P PG P+G PQ R SPP
Sbjct: 250 GNQPQGPPPPPGK-PQGPPPQGGNKPQGPPP---PGKPQGPPPQGGSKSRSSRSPP--GK 303
Query: 1981 QRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQ----- 2035
+ P P +G P K + P + G PQ GP P + PPQ
Sbjct: 304 PQGPPPQGGNQPQGPPPPPGKPQGPPPQ---GGNKPQ----GPPPPGKPQGPPPQGGSKS 356
Query: 2036 --HRKDRWEEAGPPSALSSSAPGQGPEADG 2063
R + GPP ++ G P A G
Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQGPPPPAGG 386
Score = 91.3 bits (225), Expect = 1e-17
Identities = 110/419 (26%), Positives = 152/419 (36%), Gaps = 47/419 (11%)
Query: 1517 SDALMSPPPKSSLPKAELFQQEQQSAD-KPASLPPASQASNHRDPRQARRLAAETGEGEG 1575
S +L++ P+ + P+ Q S KP PP P + +G
Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 87
Query: 1576 EPLSRLSARGAQGALPERDASR------GGLVGQAPMPVPEEKEPASSPWASGEKPPAGS 1629
+P QG P+ D SR G G P + + P P PP G
Sbjct: 88 KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147
Query: 1630 EQDGWKAEPGEGTRPATVGDSSARPARRVL---LPTPPCGALQPGFPLQHDGE-RDPFTC 1685
+ PG+ P GD+ +R +R PP G QP P G+ + P
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 207
Query: 1686 PGFASQDKAL-GSAQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPGQKVG 1744
G Q G Q P+ + + + SP G+ +G P + P PPPG+ G
Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP--PPQGGNQPQGPPPPPGKPQG 265
Query: 1745 GSQPPFQGQREPGPHALGMSGLHGPNFPG-PRGPAPPFPEENIASNDGP---RGPPPARF 1800
PP QG +P GP PG P+GP P ++ +S P +GPPP
Sbjct: 266 ---PPPQGGNKP----------QGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG 312
Query: 1801 GAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAPY 1860
+GP P Q GPPP G ++ P G P+G P G K +P
Sbjct: 313 NQPQGPPPPPGKPQ-GPPPQGGNKPQGPPPPGKPQGPPPQG--------GSKSRSARSPP 363
Query: 1861 NEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPP 1919
+ G P Q Q P P G ++P P+G P P Q G PP
Sbjct: 364 GKPQGPPQQEGNNPQGP-------PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 34.3 bits (77), Expect = 1.4
Identities = 36/147 (24%), Positives = 48/147 (32%), Gaps = 17/147 (11%)
Query: 1229 PKVATVPQSEKKPSKY----PLCSADAAVSTTPPGSPPPPPPL-------PEPPVLK--- 1274
P+ PQ P K P + + S +PPG P PPP P PP K
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 327
Query: 1275 --VLSSLKP-AAPSPATAATTAAAASTAASSTASSASKTASPLEHILQTLFGKKKSFDPS 1331
KP P P + + S S K P + G +
Sbjct: 328 PPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGN 387
Query: 1332 AREPPGSTAGLPQEPKTTAEDGVPAPP 1358
++P AG PQ P + G P+ P
Sbjct: 388 PQQPQAPPAGQPQGPPRPPQGGRPSRP 414
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 101 bits (252), Expect = 7e-21
Identities = 217/873 (24%), Positives = 285/873 (32%), Gaps = 173/873 (19%)
Query: 1423 EVAYDPEDETILEEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEEL 1482
EV D +++ LEE K T ++ M N P L+EQ K+
Sbjct: 520 EVLNDRKEDIKLEEKKKTQAEIEQEMATLQYTN--------------PQLLEQLKIERLA 565
Query: 1483 NKQIEEQKRQLEEQEEALRQQRAAVGVSMAHFSVSDALMSPPPKSSLPKAELFQQEQQSA 1542
KQ+E+ + L Q P S +P+ FQQ S
Sbjct: 566 QKQVEQIQPPPSSGTPLLGPQ---------------PFPGQGPMSQIPQG--FQQPHPSQ 608
Query: 1543 DKP---ASLPPASQASNHRDPRQARRLAAE---TGEGEGEPLSRLSARGAQG---ALPER 1593
P A + P R P ++ + +G G P + +G QG LP R
Sbjct: 609 QMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLP-R 667
Query: 1594 DASRGGLVGQAPMPVPEEK-EPASSPWASGEKPPAGSEQDGWKAEPGEGTRPATVGDSSA 1652
G G P P P P G P G G + PG G
Sbjct: 668 PQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHM--GPQGPPGPQGHIGPQGPPGP 725
Query: 1653 RPARRVLLPTPPCGALQPGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRS 1712
+ P G P P G P G G L+ G
Sbjct: 726 QGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQ 785
Query: 1713 SSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHAL-GMSGLHGPNF 1771
P G RE Q +G PP Q++ G PP G GP + G + G
Sbjct: 786 GPP-----GPRENQGPAPQGMIMGHPP-QEMRGPHPP-GGLLGHGPQEMRGPQEIRGMQG 838
Query: 1772 PGPRGPAPPFPEENIASNDGPRGPPPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPSYL 1831
P P+G P+E RGPP ++ +Q+GP G GPPP G +GP
Sbjct: 839 PPPQGSMLGPPQEL-------RGPPGSQ--SQQGPP----QGSLGPPPQGGMQGPP---- 881
Query: 1832 GGPRGVAPSQFEERKDPHGEKREFQDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGG 1891
GP+G Q + PH + P F+ ++ P LG APF G
Sbjct: 882 -GPQG----QQNPARGPHPSQ-------------GPIPFQ-QQKTPLLGDGPRAPFNQEG 922
Query: 1892 QRR---PLLSQL--KGPRGGPPPSQFGGQRGP-------PPGHFVGPRGP--HPSQFETA 1937
Q PL+ L +G +G PP G GP PP H +GP H
Sbjct: 923 QSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPE 982
Query: 1938 RGPHPNQFEGPRGQAPNFMPGPRGIQPQQFED----QRVHSPPRFTNQRAPAPLQFGGLR 1993
GP F G GQ P RG P +D H RF ++ +F G
Sbjct: 983 HGPERGPFRG--GQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLR----EFEGRG 1036
Query: 1994 GSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRK-----DRWEEAGPPS 2048
G P EK + GP P PP HR+ R GPP
Sbjct: 1037 GPLPQEEKWR----------------RGGPGP-----PFPPDHREFSEGDGRGAARGPPG 1075
Query: 2049 ALSSSAPG--------QGPEADGQWASADFREGKGHEYRNQTFEGRQRERF----DVGPK 2096
A PG + P G+ FR G + + R R+ F D GP+
Sbjct: 1076 AWEGRRPGDERFPRDPEDPRFRGR-REESFRRGAPPRHEGRA-PPRGRDGFPGPEDFGPE 1133
Query: 2097 EK-PLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSA 2155
E E A+GR R R RG R+ P E+ R WD NRE
Sbjct: 1134 ENFDASEEAARGRDLRGRGRGTPRG---GRKGLLPTPDEFPRFEGGRKPDSWDGNREPGP 1190
Query: 2156 NRDREREADR------GKEWDRSRERSRNRE---------RERDRRRDRDRSRSRERDRD 2200
+ R+ R SRERS + + R+R S RE +
Sbjct: 1191 GHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAP 1250
Query: 2201 KARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
+RG K R + R PK S + D
Sbjct: 1251 GGPSEDRG--GKGRGGPGPAQRVPKSGRSSSLD 1281
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 100 bits (249), Expect = 2e-20
Identities = 69/173 (39%), Positives = 91/173 (52%), Gaps = 20/173 (11%)
Query: 2077 EYRNQTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDWDRPREW 2135
E Q RQR+R +EK E E D + DR R+R R R+ RER DR RE
Sbjct: 59 ERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRET 118
Query: 2136 D--------RHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRE-----RSRNRERE 2182
+ R RD+ +D +R R+R D++RE + K+ DR RE R R+RERE
Sbjct: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERE 178
Query: 2183 RDRRRDRDRSRSRERDRDKARDRERGRDR-----KDRSKSKESARDPKPEASR 2230
R ++R+ R R RER R+K DRER RDR KDR + +E+ RD E R
Sbjct: 179 RQKQRETRRDRDRERQREK-EDRERDRDRQKEREKDRYRERETGRDRDKERDR 230
Score = 98.2 bits (243), Expect = 8e-20
Identities = 57/142 (40%), Positives = 82/142 (57%), Gaps = 8/142 (5%)
Query: 2100 LEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDR 2159
+ E + Q R+R +ER R RE + DR R+ R R++ RD DR RER +RDR
Sbjct: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
Query: 2160 EREADRGKEWDRSRERSRNRERERDRRR----DRDRSRSRERDRDKAR---DRERGRDR- 2211
E E +R +E +R R+R R ++RER R+R D+DR E+DRD+ R + ER RDR
Sbjct: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRE 176
Query: 2212 KDRSKSKESARDPKPEASRASD 2233
++R K +E+ RD E R +
Sbjct: 177 RERQKQRETRRDRDRERQREKE 198
Score = 95.1 bits (235), Expect = 7e-19
Identities = 59/140 (42%), Positives = 84/140 (60%), Gaps = 10/140 (7%)
Query: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
R+RER+ +E E + + R DR+RE++R R RE D+ RE + +D+D R
Sbjct: 106 RKRERWGDRDRETETERQEERER-QRDRKREKDRERQRQREIGIDKDREIETEKDRDRER 164
Query: 2146 DWDRNRERSANRDREREADRGKEWDRSRERSR---NRERERDRRRDRDRSRSRER----D 2198
+ ER +R+RER+ R DR RER R +RER+RDR+++R++ R RER D
Sbjct: 165 EMGET-ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRD 223
Query: 2199 RDKARDRERGRDRKDRSKSK 2218
RDK RDRER R+ KDR + K
Sbjct: 224 RDKERDRERQRE-KDRDRQK 242
Score = 71.2 bits (173), Expect = 1e-11
Identities = 48/141 (34%), Positives = 67/141 (47%), Gaps = 21/141 (14%)
Query: 2069 DFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERD 2128
D + K E + Q G ++R K++ E + DR RER++ R R+RD
Sbjct: 131 DRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRD 190
Query: 2129 WDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRD 2188
+R RE +D RD DR +ER +R RERE R +RD+ RD
Sbjct: 191 RERQRE-----KEDRERDRDRQKEREKDRYRERETGR----------------DRDKERD 229
Query: 2189 RDRSRSRERDRDKARDRERGR 2209
R+R R ++RDR KA D GR
Sbjct: 230 RERQREKDRDRQKAIDCVPGR 250
Score = 52.8 bits (125), Expect = 4e-06
Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 9/90 (10%)
Query: 2153 RSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDR--DKARDRERGRD 2210
RS DR+ RG + R R R+RER+R+R R + R RE+DR +K RDR+R RD
Sbjct: 36 RSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRD 95
Query: 2211 R-------KDRSKSKESARDPKPEASRASD 2233
R +DR + + RD + E R +
Sbjct: 96 RERQRWRDRDRKRERWGDRDRETETERQEE 125
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
sapiens]
Length = 624
Score = 95.9 bits (237), Expect = 4e-19
Identities = 59/179 (32%), Positives = 92/179 (51%), Gaps = 22/179 (12%)
Query: 2066 ASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSR 2125
A+ + GK +E + GR R + K + R + + R R N SR
Sbjct: 291 AAIEPESGKSNERKG----GRSRSH----TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSR 342
Query: 2126 ERDWDRPREWDRHRDKDSSRDWDRNRERSANRDRE-------READRGKEWDRSRERSRN 2178
R DR R H+ + SR+ ++R RS +RD+ +E +R KE DR +ER R
Sbjct: 343 SRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 402
Query: 2179 RERERDRRR----DRDRSRSRERDRDKARDRERGRDR---KDRSKSKESARDPKPEASR 2230
+ERE+++ R DRD+ R ++R++DK +DRER R++ KDR K KE +D + E +
Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461
Score = 89.7 bits (221), Expect = 3e-17
Identities = 44/170 (25%), Positives = 99/170 (58%), Gaps = 11/170 (6%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRA-SEDRRRE-RERGRNWSRERDWDR 2131
+ H + R+R + + K E ++ R+ S D+R++ RE+ + R ++ DR
Sbjct: 336 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 395
Query: 2132 PREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDR 2191
+E +R ++++ ++ +N++R R+++RE D+ K+ +R RE+ ++R++++ +++D+
Sbjct: 396 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 455
Query: 2192 SRSRERDRDKARDRERGRDRKDRS---------KSKESARDPKPEASRAS 2232
+ RE+DR K D +R +D+K R+ +S+ S+R+ + SR+S
Sbjct: 456 EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS 505
Score = 88.2 bits (217), Expect = 8e-17
Identities = 56/179 (31%), Positives = 94/179 (52%), Gaps = 24/179 (13%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASE-DRRRERERGRNWSRERDW 2129
RE + R+ + + R+ R + KE+ E+ + R E +R +E+ERG+N +D
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN----KDR 417
Query: 2130 DRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDR 2189
D+ RE DR +DK+ R+ +R +E +RD+E+E KE D+ +ER ++R +E D +R +
Sbjct: 418 DKEREKDREKDKEKDREREREKEHEKDRDKEKE----KEQDKEKEREKDRSKEIDEKRKK 473
Query: 2190 D--------------RSRSRERDRDKARDRERGRD-RKDRSKSKESARDPKPEASRASD 2233
D RSRS R+R + R R R R ++ ++S+R P P + D
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 532
Score = 83.6 bits (205), Expect = 2e-15
Identities = 47/162 (29%), Positives = 88/162 (54%), Gaps = 4/162 (2%)
Query: 2071 REGKGHEYRNQTFEGRQ-RERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDW 2129
R H+ R+++ E R+ R R K K E + +++ RE+ER R RE++
Sbjct: 350 RSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK 409
Query: 2130 DRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDR 2189
+R + DR ++++ R+ D+ ++R R++E E DR KE + +E+ + +ERE+DR ++
Sbjct: 410 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KEKEQDKEKEREKDRSKEI 467
Query: 2190 DRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRA 2231
D R +++ + + R R+ RS S+E R +SR+
Sbjct: 468 DEKRKKDK-KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 508
Score = 83.6 bits (205), Expect = 2e-15
Identities = 41/138 (29%), Positives = 84/138 (60%), Gaps = 8/138 (5%)
Query: 2108 RASEDRRRERERGRNWSRERDWD---RPREWDRHRDKDSSRDWDRNRERSANRDREREAD 2164
+ S+ R R + R R+ SR++ D + +E +R ++KD ++ +R +ER ++R + D
Sbjct: 357 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD 416
Query: 2165 RGKEWDRSRERSRNRERERDR----RRDRDRSRSRERDRDKARDRERGRDRKDRSKSKES 2220
R KE ++ RE+ + ++RER+R +DRD+ + +E+D++K R+++R ++ ++ K +
Sbjct: 417 RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK 476
Query: 2221 ARDPKPEASRASDAGTAS 2238
+R P P + AS +S
Sbjct: 477 SRTP-PRSYNASRRSRSS 493
Score = 68.2 bits (165), Expect = 9e-11
Identities = 46/154 (29%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDWDRP 2132
K E + + R++E+ K++ E E D + +DR RERE +E + DR
Sbjct: 393 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE------KEHEKDRD 446
Query: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRS 2192
+E ++ +DK+ R+ DR++E R +++++ + RSR+ RER RRR R S
Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 506
Query: 2193 RSRERDRDKARDRERG---RDRKDRSKSKESARD 2223
RS + R R R R + K +E RD
Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 540
Score = 65.9 bits (159), Expect = 4e-10
Identities = 41/124 (33%), Positives = 66/124 (53%), Gaps = 9/124 (7%)
Query: 2116 ERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRN-RERSANRDREREADRGKEWDRSRE 2174
E E G+ S ER R R R + + SS+ R R +S +R R R ++ DR R
Sbjct: 294 EPESGK--SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS 351
Query: 2175 RSRNRERERDRRRDRDRSRSRERD-----RDKARDRERGRDRKDRSKSKESARDPKPEAS 2229
+S +++R + R R + RSRS RD R+K +++ER ++ KDR K +E ++ + E
Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE-KDREKEREREKEREKEKE 410
Query: 2230 RASD 2233
R +
Sbjct: 411 RGKN 414
Score = 41.2 bits (95), Expect = 0.012
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 12/94 (12%)
Query: 2149 RNRERSANRDREREADRGKEWDRSRERSRNRERERDR-------RRDRDRSRSRERDRDK 2201
R RE + E + GK +R RSR+ R + R RR R +S+ R R ++
Sbjct: 281 RVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNR 340
Query: 2202 ARDRERGRDR-----KDRSKSKESARDPKPEASR 2230
+R R++ R R K RSKS+E + SR
Sbjct: 341 SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSR 374
Score = 37.4 bits (85), Expect = 0.17
Identities = 45/221 (20%), Positives = 81/221 (36%), Gaps = 24/221 (10%)
Query: 52 PPQQQLGLSLRRSGRQPKRTERVEQFLTIA---------RRRGRRSMPVSLEDSGEPTSC 102
PP+ + + KR + F++ A R+G RS + S +
Sbjct: 263 PPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKS 322
Query: 103 PATDAETASEGSVESASETRS---------GPQSASTAVKERPASSEKVKGGDDHDDTSD 153
+ + S+ S + +RS P + +ER S + D DT +
Sbjct: 323 HSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTRE 382
Query: 154 SDSDGLTLKELQNRLRRKREQE---PTERPLKGIQSRLRKKRREEGPAETVGSEASDTVE 210
+ +KE R+RE+E ER + + R+K RE+ + E E
Sbjct: 383 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 442
Query: 211 GVLPSKQEPENDQGVVSQAGKDDRESKLEGKAAQDIKDEEP 251
++E E D+ + + DR +++ K +D K P
Sbjct: 443 KDRDKEKEKEQDK---EKEREKDRSKEIDEKRKKDKKSRTP 480
Score = 35.4 bits (80), Expect = 0.63
Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 27/164 (16%)
Query: 2066 ASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSR 2125
AS R R ++ + R K K P + R +D++RE+E
Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE------- 538
Query: 2126 ERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDR 2185
RD S R R RERS + + GKE E++ +E++
Sbjct: 539 -------------RDHISER---RERERSTSMRKSSNDRDGKE---KLEKNSTSLKEKEH 579
Query: 2186 RRDRDRSRSRE-RDRDKARDRERGRDRKDRSKSKESARDPKPEA 2228
++ D S S+E D+D R E + E K EA
Sbjct: 580 NKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEA 623
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
sapiens]
Length = 508
Score = 95.9 bits (237), Expect = 4e-19
Identities = 59/179 (32%), Positives = 92/179 (51%), Gaps = 22/179 (12%)
Query: 2066 ASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSR 2125
A+ + GK +E + GR R + K + R + + R R N SR
Sbjct: 175 AAIEPESGKSNERKG----GRSRSH----TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSR 226
Query: 2126 ERDWDRPREWDRHRDKDSSRDWDRNRERSANRDRE-------READRGKEWDRSRERSRN 2178
R DR R H+ + SR+ ++R RS +RD+ +E +R KE DR +ER R
Sbjct: 227 SRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 286
Query: 2179 RERERDRRR----DRDRSRSRERDRDKARDRERGRDR---KDRSKSKESARDPKPEASR 2230
+ERE+++ R DRD+ R ++R++DK +DRER R++ KDR K KE +D + E +
Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345
Score = 89.7 bits (221), Expect = 3e-17
Identities = 44/170 (25%), Positives = 99/170 (58%), Gaps = 11/170 (6%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRA-SEDRRRE-RERGRNWSRERDWDR 2131
+ H + R+R + + K E ++ R+ S D+R++ RE+ + R ++ DR
Sbjct: 220 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 279
Query: 2132 PREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDR 2191
+E +R ++++ ++ +N++R R+++RE D+ K+ +R RE+ ++R++++ +++D+
Sbjct: 280 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 339
Query: 2192 SRSRERDRDKARDRERGRDRKDRS---------KSKESARDPKPEASRAS 2232
+ RE+DR K D +R +D+K R+ +S+ S+R+ + SR+S
Sbjct: 340 EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS 389
Score = 88.2 bits (217), Expect = 8e-17
Identities = 56/179 (31%), Positives = 94/179 (52%), Gaps = 24/179 (13%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASE-DRRRERERGRNWSRERDW 2129
RE + R+ + + R+ R + KE+ E+ + R E +R +E+ERG+N +D
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN----KDR 301
Query: 2130 DRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDR 2189
D+ RE DR +DK+ R+ +R +E +RD+E+E KE D+ +ER ++R +E D +R +
Sbjct: 302 DKEREKDREKDKEKDREREREKEHEKDRDKEKE----KEQDKEKEREKDRSKEIDEKRKK 357
Query: 2190 D--------------RSRSRERDRDKARDRERGRD-RKDRSKSKESARDPKPEASRASD 2233
D RSRS R+R + R R R R ++ ++S+R P P + D
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 416
Score = 83.6 bits (205), Expect = 2e-15
Identities = 47/162 (29%), Positives = 88/162 (54%), Gaps = 4/162 (2%)
Query: 2071 REGKGHEYRNQTFEGRQ-RERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDW 2129
R H+ R+++ E R+ R R K K E + +++ RE+ER R RE++
Sbjct: 234 RSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK 293
Query: 2130 DRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDR 2189
+R + DR ++++ R+ D+ ++R R++E E DR KE + +E+ + +ERE+DR ++
Sbjct: 294 ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KEKEQDKEKEREKDRSKEI 351
Query: 2190 DRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRA 2231
D R +++ + + R R+ RS S+E R +SR+
Sbjct: 352 DEKRKKDK-KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 392
Score = 83.6 bits (205), Expect = 2e-15
Identities = 41/138 (29%), Positives = 84/138 (60%), Gaps = 8/138 (5%)
Query: 2108 RASEDRRRERERGRNWSRERDWD---RPREWDRHRDKDSSRDWDRNRERSANRDREREAD 2164
+ S+ R R + R R+ SR++ D + +E +R ++KD ++ +R +ER ++R + D
Sbjct: 241 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD 300
Query: 2165 RGKEWDRSRERSRNRERERDR----RRDRDRSRSRERDRDKARDRERGRDRKDRSKSKES 2220
R KE ++ RE+ + ++RER+R +DRD+ + +E+D++K R+++R ++ ++ K +
Sbjct: 301 RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK 360
Query: 2221 ARDPKPEASRASDAGTAS 2238
+R P P + AS +S
Sbjct: 361 SRTP-PRSYNASRRSRSS 377
Score = 68.2 bits (165), Expect = 9e-11
Identities = 46/154 (29%), Positives = 75/154 (48%), Gaps = 10/154 (6%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLE-EPDAQGRASEDRRRERERGRNWSRERDWDRP 2132
K E + + R++E+ K++ E E D + +DR RERE +E + DR
Sbjct: 277 KDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE------KEHEKDRD 330
Query: 2133 REWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRS 2192
+E ++ +DK+ R+ DR++E R +++++ + RSR+ RER RRR R S
Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 390
Query: 2193 RSRERDRDKARDRERG---RDRKDRSKSKESARD 2223
RS + R R R R + K +E RD
Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 424
Score = 65.9 bits (159), Expect = 4e-10
Identities = 41/124 (33%), Positives = 66/124 (53%), Gaps = 9/124 (7%)
Query: 2116 ERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRN-RERSANRDREREADRGKEWDRSRE 2174
E E G+ S ER R R R + + SS+ R R +S +R R R ++ DR R
Sbjct: 178 EPESGK--SNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS 235
Query: 2175 RSRNRERERDRRRDRDRSRSRERD-----RDKARDRERGRDRKDRSKSKESARDPKPEAS 2229
+S +++R + R R + RSRS RD R+K +++ER ++ KDR K +E ++ + E
Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE-KDREKEREREKEREKEKE 294
Query: 2230 RASD 2233
R +
Sbjct: 295 RGKN 298
Score = 41.2 bits (95), Expect = 0.012
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 12/94 (12%)
Query: 2149 RNRERSANRDREREADRGKEWDRSRERSRNRERERDR-------RRDRDRSRSRERDRDK 2201
R RE + E + GK +R RSR+ R + R RR R +S+ R R ++
Sbjct: 165 RVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNR 224
Query: 2202 ARDRERGRDR-----KDRSKSKESARDPKPEASR 2230
+R R++ R R K RSKS+E + SR
Sbjct: 225 SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSR 258
Score = 37.4 bits (85), Expect = 0.17
Identities = 45/221 (20%), Positives = 81/221 (36%), Gaps = 24/221 (10%)
Query: 52 PPQQQLGLSLRRSGRQPKRTERVEQFLTIA---------RRRGRRSMPVSLEDSGEPTSC 102
PP+ + + KR + F++ A R+G RS + S +
Sbjct: 147 PPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKS 206
Query: 103 PATDAETASEGSVESASETRS---------GPQSASTAVKERPASSEKVKGGDDHDDTSD 153
+ + S+ S + +RS P + +ER S + D DT +
Sbjct: 207 HSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTRE 266
Query: 154 SDSDGLTLKELQNRLRRKREQE---PTERPLKGIQSRLRKKRREEGPAETVGSEASDTVE 210
+ +KE R+RE+E ER + + R+K RE+ + E E
Sbjct: 267 KIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHE 326
Query: 211 GVLPSKQEPENDQGVVSQAGKDDRESKLEGKAAQDIKDEEP 251
++E E D+ + + DR +++ K +D K P
Sbjct: 327 KDRDKEKEKEQDK---EKEREKDRSKEIDEKRKKDKKSRTP 364
Score = 35.4 bits (80), Expect = 0.63
Identities = 39/164 (23%), Positives = 59/164 (35%), Gaps = 27/164 (16%)
Query: 2066 ASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSR 2125
AS R R ++ + R K K P + R +D++RE+E
Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE------- 422
Query: 2126 ERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDR 2185
RD S R R RERS + + GKE E++ +E++
Sbjct: 423 -------------RDHISER---RERERSTSMRKSSNDRDGKE---KLEKNSTSLKEKEH 463
Query: 2186 RRDRDRSRSRE-RDRDKARDRERGRDRKDRSKSKESARDPKPEA 2228
++ D S S+E D+D R E + E K EA
Sbjct: 464 NKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEA 507
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 94.4 bits (233), Expect = 1e-18
Identities = 87/293 (29%), Positives = 114/293 (38%), Gaps = 41/293 (13%)
Query: 1703 PRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALG 1762
P+ G+ P + + R P++ PG+ P P G + G PP + GP G
Sbjct: 68 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP--PGKPQGPPPQG 125
Query: 1763 MSGLHGPNFPG-PRGPAPPFPEENIASNDGPRGPPPARFGAQKGPIPSLFSGQHGPPPY- 1820
+ GP PG P+GP P + PR PP G +GP P + GPPP
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSR-----SPRSPP----GKPQGPPPQGGNQPQGPPPPP 176
Query: 1821 GDSRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAPYNEVTGAPAQFEGTEQAPFLG 1880
G +GP P P+G P + P G+K +P + G P Q Q P
Sbjct: 177 GKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP--- 233
Query: 1881 SRGGAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETARGP 1940
P G P+G PP Q PPPG GP S+ ++AR P
Sbjct: 234 -----PPPPG-----------KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP 277
Query: 1941 HPNQFEGP---RGQAPNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFG 1990
P + +GP G P P P G PQQ +PP Q P P Q G
Sbjct: 278 -PGKPQGPPQQEGNNPQGPPPPAGGNPQQ-----PQAPPAGQPQGPPRPPQGG 324
Score = 90.5 bits (223), Expect = 2e-17
Identities = 96/360 (26%), Positives = 136/360 (37%), Gaps = 46/360 (12%)
Query: 1566 LAAETGEGEGEPLSRLSARGAQGALPERDASRGGLVGQAPMPVPEEKEPASSPWASGEKP 1625
LA + + E +S+ + P+ + +GG Q P P P + + P
Sbjct: 11 LALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP---------P 61
Query: 1626 PAGSEQDGWKAEPGEGTRPATVGDSSARPARRVLLP--TPPCGALQPGFPLQHDGERDPF 1683
P G + PG+ P GD S P P PP G QP + P
Sbjct: 62 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP---------QGPP 112
Query: 1684 TCPGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPGQKV 1743
PG G + P+ G+ P + + R P++ PG+ P P G +
Sbjct: 113 PPPGKPQGPPPQGGNR---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 169
Query: 1744 GGSQPPFQGQREPGPHALGMSGLHGPNFPG-PRGPAPPFPEENIASND---GPRGPPPAR 1799
G PP + GP G GP PG P+GP PP +++ +S P+GPPP
Sbjct: 170 QGPPPP--PGKPQGPPPQGGKKPQGPPPPGKPQGP-PPQGDKSRSSQSPPGKPQGPPPQG 226
Query: 1800 FGAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAP 1859
+GP P Q GPPP G ++ P G P+G P+Q G K + +P
Sbjct: 227 GNQPQGPPPPPGKPQ-GPPPQGGNKPQGPPPPGKPQG-PPAQ-------GGSKSQSARSP 277
Query: 1860 YNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPP 1919
+ G P Q Q P P G ++P P+G P P Q G PP
Sbjct: 278 PGKPQGPPQQEGNNPQGP-------PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
Score = 77.0 bits (188), Expect = 2e-13
Identities = 83/290 (28%), Positives = 109/290 (37%), Gaps = 32/290 (11%)
Query: 1786 IASNDGPRGPPPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQFEER 1845
IA N P+GP P +GP PPP G +GP P P+G P +
Sbjct: 32 IAGN--PQGPSPQGGNKPQGP----------PPPPGKPQGPPPQGGNKPQGPPPPGKPQG 79
Query: 1846 KDPHGEKREFQDAPYNEVTGAPAQFEGTEQA--PFLGSRGGAPFQFGGQRRPLLSQLKGP 1903
P G+K +P + G P Q Q P G G P Q G RP G
Sbjct: 80 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ--GGNRPQGPPPPGK 137
Query: 1904 RGGPPP---------SQFGGQRGPPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPN 1954
GPPP S G +GPPP P+GP P + +GP P + P+G P
Sbjct: 138 PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGGKKPQGPPP- 195
Query: 1955 FMPG-PRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQG 2013
PG P+G PQ + + SPP + P P +G P K + P + +
Sbjct: 196 --PGKPQGPPPQGDKSRSSQSPP--GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 251
Query: 2014 QAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADG 2063
Q P P + S R + GPP ++ G P A G
Sbjct: 252 QGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG 301
Score = 72.8 bits (177), Expect = 4e-12
Identities = 90/346 (26%), Positives = 125/346 (36%), Gaps = 59/346 (17%)
Query: 1722 DREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPF 1781
+ P G P P G K G PP PG P+GP P
Sbjct: 26 EESPSLIAGNPQGPSPQGGNKPQGPPPP------PGK---------------PQGPPPQ- 63
Query: 1782 PEENIASNDGPRGPPPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQ 1841
+ P+GPPP G +GP P + P G +GP P P+G P
Sbjct: 64 ------GGNKPQGPPPP--GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115
Query: 1842 FE-ERKDPHGEKREFQDAPYNEVTGAPAQFEGTE--QAPFLGSRGGAPFQFGGQRRPLLS 1898
+ + P G R P + G P Q + + ++P G G P Q G Q
Sbjct: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPPPQGGNQ------ 168
Query: 1899 QLKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPG 1958
P+G PPP G +GPPP P+GP P +GP P +G + ++ PG
Sbjct: 169 ----PQGPPPPP--GKPQGPPPQGGKKPQGPPPP--GKPQGPPP---QGDKSRSSQSPPG 217
Query: 1959 PRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQAPQV 2018
P Q +Q PP + P P Q G P K + P++ + Q+ +
Sbjct: 218 KPQGPPPQGGNQPQGPPPPPGKPQGPPP-QGGNKPQGPPPPGKPQGPPAQGGSKSQSAR- 275
Query: 2019 MKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQ 2064
PG P PPQ + + PP+ + P P Q
Sbjct: 276 SPPGK------PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ 315
Score = 53.9 bits (128), Expect = 2e-06
Identities = 76/299 (25%), Positives = 95/299 (31%), Gaps = 43/299 (14%)
Query: 1540 QSADKPASLPPASQASNHRDPRQARRLAAETGEGEGEPLSRLSARGAQGALPERDASR-- 1597
Q +KP PP P +G +P QG P+ D SR
Sbjct: 42 QGGNKPQGPPPPPGKPQGPPP-----------QGGNKPQGPPPPGKPQGPPPQGDKSRSP 90
Query: 1598 ----GGLVGQAPMPVPEEKEPASSPWASGEKPPAGSEQDGWKAEPGEGTRPATVGDSSAR 1653
G G P + + P P PP G + PG+ P GD S
Sbjct: 91 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS 150
Query: 1654 PARRVLLPT--PPCGALQPGFPLQHDGE-RDPFTCPGFASQDKALGSAQYEDPRNLHSAG 1710
P P PP G QP P G+ + P G Q P +
Sbjct: 151 PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSR 210
Query: 1711 RSSSPAGETEGD--------REPQARPGEGTAPLPPPGQKVGGSQPP------------- 1749
S SP G+ +G + P PG+ P P G K G PP
Sbjct: 211 SSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK 270
Query: 1750 FQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIASNDG-PRGPP-PARFGAQKGP 1806
Q R P G G N GP PA P++ A G P+GPP P + G P
Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329
Score = 36.2 bits (82), Expect = 0.37
Identities = 35/137 (25%), Positives = 45/137 (32%), Gaps = 13/137 (9%)
Query: 1235 PQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPL-------PEPPVLK-----VLSSLKP- 1281
P KP P + S +PPG P PPP P PP K KP
Sbjct: 193 PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252
Query: 1282 AAPSPATAATTAAAASTAASSTASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAG 1341
P P A + + S S K P + G + ++P AG
Sbjct: 253 GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAG 312
Query: 1342 LPQEPKTTAEDGVPAPP 1358
PQ P + G P+ P
Sbjct: 313 QPQGPPRPPQGGRPSRP 329
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 92.8 bits (229), Expect = 3e-18
Identities = 63/182 (34%), Positives = 88/182 (48%), Gaps = 16/182 (8%)
Query: 2072 EGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRAS-------------EDRRRERE 2118
EG+ H R+++ EGR+ E D K+ EE + + +S EDR + +E
Sbjct: 57 EGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKE 116
Query: 2119 RGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRN 2178
R + R R RE RHR + R R+R R + R R +R K RSRER R
Sbjct: 117 RKSSRGRSHSRSRSRE-RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRR 175
Query: 2179 -RERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGTA 2237
R R R R R R R+RSR R R ++RDR++ R K R S+ +R P P R +
Sbjct: 176 IRSRSRSRSRHRHRTRSRSRTRSRSRDRKK-RIEKPRRFSRSLSRTPSPPPFRGRNTAMD 234
Query: 2238 SQ 2239
+Q
Sbjct: 235 AQ 236
Score = 83.2 bits (204), Expect = 3e-15
Identities = 59/196 (30%), Positives = 95/196 (48%), Gaps = 26/196 (13%)
Query: 2049 ALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGR 2108
A ++P + + + S R K H Y R+R+R + D +GR
Sbjct: 12 APEKTSPDRDKKKEQSEVSVSPRASK-HHYSRSRSRSRERKR-----------KSDNEGR 59
Query: 2109 ASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSA------NRDRERE 2162
R R +E R+ S+++ + + + H DK+ S D R R S+ ++ +ER+
Sbjct: 60 KHRSRSRSKEGRRHESKDKS-SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERK 118
Query: 2163 ADRGKEWDRSRER-------SRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRS 2215
+ RG+ RSR R SR R++ R R R+R +SRSR R+R K+R R R R R+ RS
Sbjct: 119 SSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRS 178
Query: 2216 KSKESARDPKPEASRA 2231
+S+ +R SR+
Sbjct: 179 RSRSRSRHRHRTRSRS 194
Score = 65.9 bits (159), Expect = 4e-10
Identities = 39/148 (26%), Positives = 71/148 (47%), Gaps = 10/148 (6%)
Query: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
+++ V P+ ++ R+ E +R+ GR + R R +E RH KD S
Sbjct: 24 KEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR---KHRSRSRSKEGRRHESKDKSS 80
Query: 2146 DWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDR 2205
++ E + D+E +D+G+E R S +R +R++R SR R R ++R+R
Sbjct: 81 KKHKSEEHN---DKEHSSDKGRE----RLNSSENGEDRHKRKERKSSRGRSHSRSRSRER 133
Query: 2206 ERGRDRKDRSKSKESARDPKPEASRASD 2233
++R KS+ +R+ K SR+ +
Sbjct: 134 RHRSRSRERKKSRSRSRERKKSRSRSRE 161
Score = 59.7 bits (143), Expect = 3e-08
Identities = 50/189 (26%), Positives = 83/189 (43%), Gaps = 15/189 (7%)
Query: 2035 QHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVG 2094
+H D+ E L+SS G+ + S+ R R + R RER
Sbjct: 92 EHSSDKGRER-----LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER---- 142
Query: 2095 PKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERS 2154
K + + S R RER++ R+ SRER R R R R + R R+R RS
Sbjct: 143 ---KKSRSRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRHRTRSRSRTRS 198
Query: 2155 ANRDREREADRGKEWDRSRERSRNRE--RERDRRRDRDRSRSRERDRDKARDRERGRDRK 2212
+RDR++ ++ + + RS R+ + R R+ D + +R +R K +R ++
Sbjct: 199 RSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMV 258
Query: 2213 DRSKSKESA 2221
++ K +E A
Sbjct: 259 EKQKQQEIA 267
Score = 53.9 bits (128), Expect = 2e-06
Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 20/164 (12%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPR 2133
KG E N + G R + + ++ R R R RER ++ SR R+ + R
Sbjct: 97 KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156
Query: 2134 EWDRHRDKDSSRDWDR---------NRERSANRDREREADRGKEWDRSRERSRNRERERD 2184
R R K SR +R +R R +R R R RSR R R + E+
Sbjct: 157 SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSR------TRSRSRDRKKRIEKP 210
Query: 2185 RRRDRDRSRSRE----RDRDKARDRERGRDRK-DRSKSKESARD 2223
RR R SR+ R R+ A D + R+ +R+K + R+
Sbjct: 211 RRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 254
Score = 50.8 bits (120), Expect = 1e-05
Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 10/104 (9%)
Query: 2142 DSSRDWDRNRERSANRDRERE------ADRGKEWDRSRERSRNRERER----DRRRDRDR 2191
D+ RD + S +RD+++E + R + SR RSR+RER+R + R+ R R
Sbjct: 5 DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 2192 SRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAG 2235
SRS+E R +++D+ + + + KE + D E +S+ G
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENG 108
Score = 48.9 bits (115), Expect = 6e-05
Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 47/171 (27%)
Query: 2109 ASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANR----------- 2157
A+ D R+ S +RD + + + S + R+R RS R
Sbjct: 2 AASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKH 61
Query: 2158 ----------------------------DREREADRGKEWDRSRERSRNRERERDRRRDR 2189
D+E +D+G+E S E +R + ++R+ R
Sbjct: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSR 121
Query: 2190 DRSRSRERDRDKARDRERGRDRK-------DRSKSKESARDPKPEASRASD 2233
RS SR R R++ R R R R+RK +R KS+ +R+ K SR+ +
Sbjct: 122 GRSHSRSRSRER-RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRE 171
Score = 47.4 bits (111), Expect = 2e-04
Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 9/124 (7%)
Query: 2126 ERDWDRPREWDRHRDKD--------SSRDWDRNRERSANRDREREADRGKEWDRSRERSR 2177
ERD P + RDK S R + RS +R RER+ E + R RSR
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
Query: 2178 NRERERDRRRDRDRSRSR-ERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGT 2236
++E R +D+ + + E DK ++GR+R + S++ E K S + +
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 126
Query: 2237 ASQA 2240
S++
Sbjct: 127 RSRS 130
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 [Homo
sapiens]
Length = 1125
Score = 90.9 bits (224), Expect = 1e-17
Identities = 142/515 (27%), Positives = 196/515 (38%), Gaps = 116/515 (22%)
Query: 1736 LPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIASNDGPRGP 1795
+PPP PP G +P P G+ P F GP P PP P + P
Sbjct: 677 VPPPQVPPHQPGPPVVGALQP-PAFTPPLGIPPPGF-GPGVPPPPPPPPFLRPGFNPMHL 734
Query: 1796 PPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQFEERKDPHGEKREF 1855
PP GP P + PPP+ P+ + G RG A S K
Sbjct: 735 PPGFL--PPGPPPPITPPVSIPPPHTPPIS-IPNLVSGARGNAESG-------DSVKMYG 784
Query: 1856 QDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQR---------RPLLSQLKGPRGG 1906
P T P T+ LG++G AP G + RP L L+ P G
Sbjct: 785 SAVPPAAPTNLPTP-PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGM 843
Query: 1907 PPPSQFGGQRGP--PPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPGPRGIQP 1964
PPP QR P PP P PH RGP P GP G A MP P G++
Sbjct: 844 PPPHL---QRFPLMPPR----PMPPHMMH----RGPPP----GPGGFA---MPPPHGMKG 885
Query: 1965 QQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPR 2024
PP R P GL G P E R Q PQ + P+
Sbjct: 886 P--------FPPHGPFVR---PGGMPGLGGPGPGPGGPEDRDGR----QQPPQQPQQQPQ 930
Query: 2025 PLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFE 2084
P + P P Q ++ + PP + Q P+ FR ++ R Q
Sbjct: 931 P--QAPQQPQQQQQQQ-----PPPSQQPPPTQQQPQ--------QFR----NDNRQQFNS 971
Query: 2085 GRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSS 2144
GR +ERF GR S R E +R R +R D D + +RD+
Sbjct: 972 GRDQERF---------------GRRSFGNRVENDRERYGNRNDDRD-----NSNRDR--- 1008
Query: 2145 RDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARD 2204
R+W R RS +RDR R+ + +R+R S +R+RERD SR+R+ + ++
Sbjct: 1009 REWGR---RSPDRDRHRDLE-----ERNRRSSGHRDRERD---------SRDRESRREKE 1051
Query: 2205 RERGRDRKDRSKSKESARDPKPEASRASDAGTASQ 2239
RG+++ + + + +P S+ + TAS+
Sbjct: 1052 EARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASE 1086
Score = 49.7 bits (117), Expect = 3e-05
Identities = 25/68 (36%), Positives = 36/68 (52%)
Query: 2160 EREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKE 2219
+ R + RS +R R+R R RR RSRSR RDR + R R ++R+DR K +E
Sbjct: 430 DNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERE 489
Query: 2220 SARDPKPE 2227
+ P+
Sbjct: 490 RRQKGLPQ 497
Score = 48.1 bits (113), Expect = 9e-05
Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 16/135 (11%)
Query: 2095 PKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERS 2154
P P+++P +AS + E + +E + ++P + R +R ++R RS
Sbjct: 385 PPTPPVQQPF---QASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNR---KSRSRS 438
Query: 2155 ANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDR 2214
A+R +R R RS +R R RR R RSR R R ++R +ER K+R
Sbjct: 439 ASRSPKRR----------RSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKER 488
Query: 2215 SKSKESARDPKPEAS 2229
+ ++ KPE +
Sbjct: 489 ERRQKGLPQVKPETA 503
Score = 43.9 bits (102), Expect = 0.002
Identities = 40/183 (21%), Positives = 68/183 (37%), Gaps = 6/183 (3%)
Query: 47 PLEPPPPQQQLGLSLRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATD 106
P + PPP QQ R RQ + R ++ R GRRS +E+ E D
Sbjct: 947 PSQQPPPTQQQPQQFRNDNRQQFNSGRDQE------RFGRRSFGNRVENDRERYGNRNDD 1000
Query: 107 AETASEGSVESASETRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQN 166
+ ++ E + + + R +S + + D D S + + KE
Sbjct: 1001 RDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPE 1060
Query: 167 RLRRKREQEPTERPLKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVV 226
R + E P+ + + E+G +E + S+ + S EPE D G
Sbjct: 1061 VTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSA 1120
Query: 227 SQA 229
++A
Sbjct: 1121 AEA 1123
Score = 39.7 bits (91), Expect = 0.034
Identities = 76/353 (21%), Positives = 120/353 (33%), Gaps = 58/353 (16%)
Query: 1255 TTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPL 1314
T GSPPPP + P + + PA P ++ AA A ++ L
Sbjct: 149 TNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQ-------L 201
Query: 1315 EHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFSKDK 1374
+ ILQT ++PP PQ P ++ V A VQ K
Sbjct: 202 QQILQTF-----------QQPP-----KPQSP--ALDNAVMAQ------VQAITAQLKTT 237
Query: 1375 ALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDETIL 1434
+ E + P E+ + AFD +L++ R + + PEA ++E D T
Sbjct: 238 PTQPSEQKAAFPPPEQ---KTAFDKKLLD---RFDYDDEPEAVEESKKE---DTTAVTTT 288
Query: 1435 EEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLE 1494
A V P + P P A P QQ + + Q R +
Sbjct: 289 APA-AAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 347
Query: 1495 EQEEALRQQ-RAAVGVSMAHFSVSDALMSPPPKSSL-----PKAELFQQEQQSADKPASL 1548
Q++ + Q M F + PP + P + FQ Q+ ++P +
Sbjct: 348 IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQ 407
Query: 1549 PPASQASNHRDP--RQARRLAAETGEGEGEPLSRLSARGAQGALPERDASRGG 1599
P Q P ++ +R ++ + SR P+R SR G
Sbjct: 408 KPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR---------SPKRRRSRSG 451
Score = 38.1 bits (87), Expect = 0.098
Identities = 37/104 (35%), Positives = 43/104 (41%), Gaps = 22/104 (21%)
Query: 1729 PGEGTAPLPPP-GQKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIA 1787
PG G +PPP G K G PP PG GM GL GP PGP GP
Sbjct: 870 PGPGGFAMPPPHGMK--GPFPPHGPFVRPG----GMPGLGGPG-PGPGGP---------E 913
Query: 1788 SNDGPRGPP--PARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPS 1829
DG + PP P + + P Q PPP S+ P P+
Sbjct: 914 DRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPP---SQQPPPT 954
Score = 35.0 bits (79), Expect = 0.83
Identities = 67/306 (21%), Positives = 110/306 (35%), Gaps = 42/306 (13%)
Query: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
SED+ R+ +G K++I QP+++ + P +V +
Sbjct: 104 SEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEG---------- 153
Query: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGI-------------KISSVH 467
+K S +P + P P LP A A + +I
Sbjct: 154 SPPPPVKVSS-----EPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTF 208
Query: 468 KRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLL 527
++P P+ + + AV+ A+ +A+ + +TP+ S+ PE+ A LL
Sbjct: 209 QQP-PKPQSPALDNAVM--AQVQAITAQL---KTTPTQPSEQKAAFPPPEQKTAFDKKLL 262
Query: 528 YKSTKEDRRS--EEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKK 585
+ +D EE + T P +AV PAP VP + A AAA+P +
Sbjct: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAV--PPAPTATVP---AAAAPAAASPPPPQ 317
Query: 586 PPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPS 645
P GF G ++P + + R G P + + G P P
Sbjct: 318 APFGFPGDGMQQPAYTQHQNMDQFQPRMMG-IQQDPMHHQVPLPPNGQMPGFGLLPTPPF 376
Query: 646 VPMASP 651
PMA P
Sbjct: 377 PPMAQP 382
Score = 33.9 bits (76), Expect = 1.8
Identities = 43/149 (28%), Positives = 52/149 (34%), Gaps = 26/149 (17%)
Query: 1219 QPEEADVPAYPKVA--TVPQSEKKPSKY--PLCSADAAVSTTPP-GSPPP------PPPL 1267
+P VP P A TVP + P + P+ A + TPP G PPP PPP
Sbjct: 660 KPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPP 719
Query: 1268 PEPPVLK--------VLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPLEHILQ 1319
P PP L+ L P P P T + T S + S E
Sbjct: 720 PPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAES--- 776
Query: 1320 TLFGKKKSFDPSAREPPGSTAGLPQEPKT 1348
G SA PP + LP P T
Sbjct: 777 ---GDSVKMYGSA-VPPAAPTNLPTPPVT 801
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 87.0 bits (214), Expect = 2e-16
Identities = 59/161 (36%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Query: 2069 DFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERD 2128
D R K + R + + R+RER + K + EE + RA + RR+R R R+ R
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRT 303
Query: 2129 WDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRR-- 2186
DR R RD SR +R R RS +R R R DR + RSR R R R + RDR+
Sbjct: 304 SDR--RCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSY 361
Query: 2187 RDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPE 2227
+ R +SR RE+DR +RG D K +S K +R+ + E
Sbjct: 362 KHRSKSRDREQDRKSKEKEKRGSDDK-KSSVKSGSREKQSE 401
Score = 86.7 bits (213), Expect = 2e-16
Identities = 57/160 (35%), Positives = 79/160 (49%), Gaps = 25/160 (15%)
Query: 2098 KPLEEPDAQGRASEDR--RRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDR-----N 2150
K EEPD R +++ R ERE+ R RE + R + R+K+ +RD +R +
Sbjct: 236 KRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRS 295
Query: 2151 RERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRD--------RSRSRERDRDKA 2202
R R ++R +R R ++ RSR R R R R RDRRR R RSRSR+R R K+
Sbjct: 296 RSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKS 355
Query: 2203 RDR----------ERGRDRKDRSKSKESARDPKPEASRAS 2232
RDR +R +DRK + K K + D K S
Sbjct: 356 RDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGS 395
Score = 62.8 bits (151), Expect = 4e-09
Identities = 45/124 (36%), Positives = 62/124 (50%), Gaps = 22/124 (17%)
Query: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDRERE----ADRGKEWDRSRERSRNRERER--- 2183
R R + RD+ ++ ER R+RERE R +E +R +ER+R+RER +
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSR 294
Query: 2184 ----------DRR----RDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEAS 2229
DRR RD RSRSRER R ++RDR R R DRS+ K +R S
Sbjct: 295 SRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH-DRSERKHRSRSRDRRRS 353
Query: 2230 RASD 2233
++ D
Sbjct: 354 KSRD 357
Score = 60.8 bits (146), Expect = 1e-08
Identities = 49/140 (35%), Positives = 76/140 (54%), Gaps = 22/140 (15%)
Query: 2105 AQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREAD 2164
A+ +A+ + +E+ R R +RD +R ++ + R++ R+ +R RER ERE
Sbjct: 221 AKIKATVEELKEKLRKRTEEPDRD-ERLKKEKQEREE---REKERERERE-----ERERK 271
Query: 2165 RGKEWDRSRERSRNRERERDRRRDRDRSR----------SRERDRDKARDRERGRDR-KD 2213
R +E + RE+ R R+RER R+R R RSR SR RD ++R RER R R +D
Sbjct: 272 RRRE-EEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD 329
Query: 2214 RSKSKESARDPKPEASRASD 2233
R +S+ R + SR+ D
Sbjct: 330 RRRSRSHDRSERKHRSRSRD 349
Score = 60.5 bits (145), Expect = 2e-08
Identities = 47/166 (28%), Positives = 72/166 (43%), Gaps = 8/166 (4%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWD 2130
R + E + R+R + D + S D +R R R R SR RD
Sbjct: 272 RRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR 331
Query: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERER---DRRR 2187
R R DR K SR DR R +S RDR+ R K DR ++R +++E+E+ D ++
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKS--RDRKSYKHRSKSRDREQDR-KSKEKEKRGSDDKK 388
Query: 2188 DRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
+S SRE+ + + D K+ ++ D K E S+
Sbjct: 389 SSVKSGSREKQSEDTNTESKESDTKNEVNG--TSEDIKSEGDTQSN 432
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 87.0 bits (214), Expect = 2e-16
Identities = 59/161 (36%), Positives = 82/161 (50%), Gaps = 5/161 (3%)
Query: 2069 DFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERD 2128
D R K + R + + R+RER + K + EE + RA + RR+R R R+ R
Sbjct: 244 DERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRT 303
Query: 2129 WDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRR-- 2186
DR R RD SR +R R RS +R R R DR + RSR R R R + RDR+
Sbjct: 304 SDR--RCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSY 361
Query: 2187 RDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPE 2227
+ R +SR RE+DR +RG D K +S K +R+ + E
Sbjct: 362 KHRSKSRDREQDRKSKEKEKRGSDDK-KSSVKSGSREKQSE 401
Score = 86.7 bits (213), Expect = 2e-16
Identities = 57/160 (35%), Positives = 79/160 (49%), Gaps = 25/160 (15%)
Query: 2098 KPLEEPDAQGRASEDR--RRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDR-----N 2150
K EEPD R +++ R ERE+ R RE + R + R+K+ +RD +R +
Sbjct: 236 KRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRS 295
Query: 2151 RERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRD--------RSRSRERDRDKA 2202
R R ++R +R R ++ RSR R R R R RDRRR R RSRSR+R R K+
Sbjct: 296 RSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKS 355
Query: 2203 RDR----------ERGRDRKDRSKSKESARDPKPEASRAS 2232
RDR +R +DRK + K K + D K S
Sbjct: 356 RDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGS 395
Score = 62.8 bits (151), Expect = 4e-09
Identities = 45/124 (36%), Positives = 62/124 (50%), Gaps = 22/124 (17%)
Query: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDRERE----ADRGKEWDRSRERSRNRERER--- 2183
R R + RD+ ++ ER R+RERE R +E +R +ER+R+RER +
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSR 294
Query: 2184 ----------DRR----RDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEAS 2229
DRR RD RSRSRER R ++RDR R R DRS+ K +R S
Sbjct: 295 SRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH-DRSERKHRSRSRDRRRS 353
Query: 2230 RASD 2233
++ D
Sbjct: 354 KSRD 357
Score = 60.8 bits (146), Expect = 1e-08
Identities = 49/140 (35%), Positives = 76/140 (54%), Gaps = 22/140 (15%)
Query: 2105 AQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREAD 2164
A+ +A+ + +E+ R R +RD +R ++ + R++ R+ +R RER ERE
Sbjct: 221 AKIKATVEELKEKLRKRTEEPDRD-ERLKKEKQEREE---REKERERERE-----ERERK 271
Query: 2165 RGKEWDRSRERSRNRERERDRRRDRDRSR----------SRERDRDKARDRERGRDR-KD 2213
R +E + RE+ R R+RER R+R R RSR SR RD ++R RER R R +D
Sbjct: 272 RRRE-EEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRD 329
Query: 2214 RSKSKESARDPKPEASRASD 2233
R +S+ R + SR+ D
Sbjct: 330 RRRSRSHDRSERKHRSRSRD 349
Score = 60.5 bits (145), Expect = 2e-08
Identities = 47/166 (28%), Positives = 72/166 (43%), Gaps = 8/166 (4%)
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWD 2130
R + E + R+R + D + S D +R R R R SR RD
Sbjct: 272 RRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR 331
Query: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERER---DRRR 2187
R R DR K SR DR R +S RDR+ R K DR ++R +++E+E+ D ++
Sbjct: 332 RSRSHDRSERKHRSRSRDRRRSKS--RDRKSYKHRSKSRDREQDR-KSKEKEKRGSDDKK 388
Query: 2188 DRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASD 2233
+S SRE+ + + D K+ ++ D K E S+
Sbjct: 389 SSVKSGSREKQSEDTNTESKESDTKNEVNG--TSEDIKSEGDTQSN 432
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 [Homo
sapiens]
Length = 1132
Score = 86.7 bits (213), Expect = 2e-16
Identities = 150/529 (28%), Positives = 204/529 (38%), Gaps = 133/529 (25%)
Query: 1728 RPGEGTAPL--PPPGQKVGGSQPPFQGQREPGPHAL--GMSGLHGPNFPGPRGPAPPFPE 1783
+P T PL PPPG G PP P P L G + +H P PG P PP P
Sbjct: 681 QPPAFTPPLGIPPPGFGPGVPPPP------PPPPFLRPGFNPMHLP--PGFLPPGPPPPI 732
Query: 1784 ENIASNDGPRGPPPARFGAQKGPIP-SLFSGQHGPPPYGDSRG-PSPSYLGGPRGVAPSQ 1841
S P PP + IP S +G + S G P P+ + G RG A S
Sbjct: 733 TPPVSIPPPHTPPIS--------IPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESG 784
Query: 1842 FEERKDPHGEKREFQDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQR-------- 1893
K P T P T+ LG++G AP G +
Sbjct: 785 -------DSVKMYGSAVPPAAPTNLPTP-PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG 836
Query: 1894 -RPLLSQLKGPRGGPPPSQFGGQRGP--PPGHFVGPRGPHPSQFETARGPHPNQFEGPRG 1950
RP L L+ P G PPP QR P PP P PH RGP P GP G
Sbjct: 837 ARPGLIPLQRPPGMPPPHL---QRFPLMPPR----PMPPHMMH----RGPPP----GPGG 881
Query: 1951 QAPNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFH 2010
A MP P G++ PP R P GL G P E R
Sbjct: 882 FA---MPPPHGMKGP--------FPPHGPFVR---PGGMPGLGGPGPGPGGPEDRDGR-- 925
Query: 2011 FQGQAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADF 2070
Q PQ + P+P + P P Q ++ + PP + Q P+ F
Sbjct: 926 --QQPPQQPQQQPQP--QAPQQPQQQQQQQ-----PPPSQQPPPTQQQPQ--------QF 968
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWD 2130
R ++ R Q GR +ERF GR S R E +R R +R D D
Sbjct: 969 R----NDNRQQFNSGRDQERF---------------GRRSFGNRVENDRERYGNRNDDRD 1009
Query: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRD 2190
+ +RD+ R+W R RS +RDR R+ + +R+R S +R+RERD
Sbjct: 1010 -----NSNRDR---REWGR---RSPDRDRHRDLE-----ERNRRSSGHRDRERD------ 1047
Query: 2191 RSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGTASQ 2239
SR+R+ + ++ RG+++ + + + +P S+ + TAS+
Sbjct: 1048 ---SRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASE 1093
Score = 49.7 bits (117), Expect = 3e-05
Identities = 25/68 (36%), Positives = 36/68 (52%)
Query: 2160 EREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKE 2219
+ R + RS +R R+R R RR RSRSR RDR + R R ++R+DR K +E
Sbjct: 415 DNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERE 474
Query: 2220 SARDPKPE 2227
+ P+
Sbjct: 475 RRQKGLPQ 482
Score = 48.1 bits (113), Expect = 9e-05
Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 16/135 (11%)
Query: 2095 PKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERS 2154
P P+++P +AS + E + +E + ++P + R +R ++R RS
Sbjct: 370 PPTPPVQQPF---QASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNR---KSRSRS 423
Query: 2155 ANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDR 2214
A+R +R R RS +R R RR R RSR R R ++R +ER K+R
Sbjct: 424 ASRSPKRR----------RSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKER 473
Query: 2215 SKSKESARDPKPEAS 2229
+ ++ KPE +
Sbjct: 474 ERRQKGLPQVKPETA 488
Score = 43.9 bits (102), Expect = 0.002
Identities = 40/183 (21%), Positives = 68/183 (37%), Gaps = 6/183 (3%)
Query: 47 PLEPPPPQQQLGLSLRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATD 106
P + PPP QQ R RQ + R ++ R GRRS +E+ E D
Sbjct: 954 PSQQPPPTQQQPQQFRNDNRQQFNSGRDQE------RFGRRSFGNRVENDRERYGNRNDD 1007
Query: 107 AETASEGSVESASETRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQN 166
+ ++ E + + + R +S + + D D S + + KE
Sbjct: 1008 RDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPE 1067
Query: 167 RLRRKREQEPTERPLKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVV 226
R + E P+ + + E+G +E + S+ + S EPE D G
Sbjct: 1068 VTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSA 1127
Query: 227 SQA 229
++A
Sbjct: 1128 AEA 1130
Score = 39.7 bits (91), Expect = 0.034
Identities = 76/353 (21%), Positives = 120/353 (33%), Gaps = 58/353 (16%)
Query: 1255 TTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPL 1314
T GSPPPP + P + + PA P ++ AA A ++ L
Sbjct: 134 TNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQ-------L 186
Query: 1315 EHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFSKDK 1374
+ ILQT ++PP PQ P ++ V A VQ K
Sbjct: 187 QQILQTF-----------QQPP-----KPQSP--ALDNAVMAQ------VQAITAQLKTT 222
Query: 1375 ALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDETIL 1434
+ E + P E+ + AFD +L++ R + + PEA ++E D T
Sbjct: 223 PTQPSEQKAAFPPPEQ---KTAFDKKLLD---RFDYDDEPEAVEESKKE---DTTAVTTT 273
Query: 1435 EEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLE 1494
A V P + P P A P QQ + + Q R +
Sbjct: 274 APA-AAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 332
Query: 1495 EQEEALRQQ-RAAVGVSMAHFSVSDALMSPPPKSSL-----PKAELFQQEQQSADKPASL 1548
Q++ + Q M F + PP + P + FQ Q+ ++P +
Sbjct: 333 IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQ 392
Query: 1549 PPASQASNHRDP--RQARRLAAETGEGEGEPLSRLSARGAQGALPERDASRGG 1599
P Q P ++ +R ++ + SR P+R SR G
Sbjct: 393 KPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR---------SPKRRRSRSG 436
Score = 35.0 bits (79), Expect = 0.83
Identities = 67/306 (21%), Positives = 110/306 (35%), Gaps = 42/306 (13%)
Query: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
SED+ R+ +G K++I QP+++ + P +V +
Sbjct: 89 SEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEG---------- 138
Query: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGI-------------KISSVH 467
+K S +P + P P LP A A + +I
Sbjct: 139 SPPPPVKVSS-----EPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTF 193
Query: 468 KRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLL 527
++P P+ + + AV+ A+ +A+ + +TP+ S+ PE+ A LL
Sbjct: 194 QQP-PKPQSPALDNAVM--AQVQAITAQL---KTTPTQPSEQKAAFPPPEQKTAFDKKLL 247
Query: 528 YKSTKEDRRS--EEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKK 585
+ +D EE + T P +AV PAP VP + A AAA+P +
Sbjct: 248 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAV--PPAPTATVP---AAAAPAAASPPPPQ 302
Query: 586 PPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPS 645
P GF G ++P + + R G P + + G P P
Sbjct: 303 APFGFPGDGMQQPAYTQHQNMDQFQPRMMG-IQQDPMHHQVPLPPNGQMPGFGLLPTPPF 361
Query: 646 VPMASP 651
PMA P
Sbjct: 362 PPMAQP 367
Score = 32.3 bits (72), Expect = 5.4
Identities = 42/164 (25%), Positives = 57/164 (34%), Gaps = 34/164 (20%)
Query: 1219 QPEEADVPAYPKVA--TVPQSEKKPSKY--PLCSADAAVSTTPP----------GSPPPP 1264
+P VP P A TVP + P + P+ A + TPP G PPPP
Sbjct: 645 KPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPP 704
Query: 1265 PPLP--EP---PVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSA-----------S 1308
PP P P P+ L P P P T + T S +S
Sbjct: 705 PPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDL 764
Query: 1309 KTASPLEHILQTLFGKKKSFDP----SAREPPGSTAGLPQEPKT 1348
+P+ ++ G +S D + PP + LP P T
Sbjct: 765 SIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVT 808
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [Homo
sapiens]
Length = 1147
Score = 86.7 bits (213), Expect = 2e-16
Identities = 150/529 (28%), Positives = 204/529 (38%), Gaps = 133/529 (25%)
Query: 1728 RPGEGTAPL--PPPGQKVGGSQPPFQGQREPGPHAL--GMSGLHGPNFPGPRGPAPPFPE 1783
+P T PL PPPG G PP P P L G + +H P PG P PP P
Sbjct: 696 QPPAFTPPLGIPPPGFGPGVPPPP------PPPPFLRPGFNPMHLP--PGFLPPGPPPPI 747
Query: 1784 ENIASNDGPRGPPPARFGAQKGPIP-SLFSGQHGPPPYGDSRG-PSPSYLGGPRGVAPSQ 1841
S P PP + IP S +G + S G P P+ + G RG A S
Sbjct: 748 TPPVSIPPPHTPPIS--------IPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESG 799
Query: 1842 FEERKDPHGEKREFQDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQR-------- 1893
K P T P T+ LG++G AP G +
Sbjct: 800 -------DSVKMYGSAVPPAAPTNLPTP-PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG 851
Query: 1894 -RPLLSQLKGPRGGPPPSQFGGQRGP--PPGHFVGPRGPHPSQFETARGPHPNQFEGPRG 1950
RP L L+ P G PPP QR P PP P PH RGP P GP G
Sbjct: 852 ARPGLIPLQRPPGMPPPHL---QRFPLMPPR----PMPPHMMH----RGPPP----GPGG 896
Query: 1951 QAPNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFH 2010
A MP P G++ PP R P GL G P E R
Sbjct: 897 FA---MPPPHGMKGP--------FPPHGPFVR---PGGMPGLGGPGPGPGGPEDRDGR-- 940
Query: 2011 FQGQAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADF 2070
Q PQ + P+P + P P Q ++ + PP + Q P+ F
Sbjct: 941 --QQPPQQPQQQPQP--QAPQQPQQQQQQQ-----PPPSQQPPPTQQQPQ--------QF 983
Query: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWD 2130
R ++ R Q GR +ERF GR S R E +R R +R D D
Sbjct: 984 R----NDNRQQFNSGRDQERF---------------GRRSFGNRVENDRERYGNRNDDRD 1024
Query: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRD 2190
+ +RD+ R+W R RS +RDR R+ + +R+R S +R+RERD
Sbjct: 1025 -----NSNRDR---REWGR---RSPDRDRHRDLE-----ERNRRSSGHRDRERD------ 1062
Query: 2191 RSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGTASQ 2239
SR+R+ + ++ RG+++ + + + +P S+ + TAS+
Sbjct: 1063 ---SRDRESRREKEEARGKEKPEVTDRAGGNKTVEPPISQVGNVDTASE 1108
Score = 49.7 bits (117), Expect = 3e-05
Identities = 25/68 (36%), Positives = 36/68 (52%)
Query: 2160 EREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKE 2219
+ R + RS +R R+R R RR RSRSR RDR + R R ++R+DR K +E
Sbjct: 430 DNRKSRSRSASRSPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERE 489
Query: 2220 SARDPKPE 2227
+ P+
Sbjct: 490 RRQKGLPQ 497
Score = 48.1 bits (113), Expect = 9e-05
Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 16/135 (11%)
Query: 2095 PKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERS 2154
P P+++P +AS + E + +E + ++P + R +R ++R RS
Sbjct: 385 PPTPPVQQPF---QASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNR---KSRSRS 438
Query: 2155 ANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDR 2214
A+R +R R RS +R R RR R RSR R R ++R +ER K+R
Sbjct: 439 ASRSPKRR----------RSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKER 488
Query: 2215 SKSKESARDPKPEAS 2229
+ ++ KPE +
Sbjct: 489 ERRQKGLPQVKPETA 503
Score = 43.9 bits (102), Expect = 0.002
Identities = 40/183 (21%), Positives = 68/183 (37%), Gaps = 6/183 (3%)
Query: 47 PLEPPPPQQQLGLSLRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATD 106
P + PPP QQ R RQ + R ++ R GRRS +E+ E D
Sbjct: 969 PSQQPPPTQQQPQQFRNDNRQQFNSGRDQE------RFGRRSFGNRVENDRERYGNRNDD 1022
Query: 107 AETASEGSVESASETRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQN 166
+ ++ E + + + R +S + + D D S + + KE
Sbjct: 1023 RDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRESRREKEEARGKEKPE 1082
Query: 167 RLRRKREQEPTERPLKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVV 226
R + E P+ + + E+G +E + S+ + S EPE D G
Sbjct: 1083 VTDRAGGNKTVEPPISQVGNVDTASELEKGVSEAAVLKPSEELPAEATSSVEPEKDSGSA 1142
Query: 227 SQA 229
++A
Sbjct: 1143 AEA 1145
Score = 39.7 bits (91), Expect = 0.034
Identities = 76/353 (21%), Positives = 120/353 (33%), Gaps = 58/353 (16%)
Query: 1255 TTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPL 1314
T GSPPPP + P + + PA P ++ AA A ++ L
Sbjct: 149 TNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQ-------L 201
Query: 1315 EHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFSKDK 1374
+ ILQT ++PP PQ P ++ V A VQ K
Sbjct: 202 QQILQTF-----------QQPP-----KPQSP--ALDNAVMAQ------VQAITAQLKTT 237
Query: 1375 ALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDETIL 1434
+ E + P E+ + AFD +L++ R + + PEA ++E D T
Sbjct: 238 PTQPSEQKAAFPPPEQ---KTAFDKKLLD---RFDYDDEPEAVEESKKE---DTTAVTTT 288
Query: 1435 EEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLE 1494
A V P + P P A P QQ + + Q R +
Sbjct: 289 APA-AAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMG 347
Query: 1495 EQEEALRQQ-RAAVGVSMAHFSVSDALMSPPPKSSL-----PKAELFQQEQQSADKPASL 1548
Q++ + Q M F + PP + P + FQ Q+ ++P +
Sbjct: 348 IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQ 407
Query: 1549 PPASQASNHRDP--RQARRLAAETGEGEGEPLSRLSARGAQGALPERDASRGG 1599
P Q P ++ +R ++ + SR P+R SR G
Sbjct: 408 KPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR---------SPKRRRSRSG 451
Score = 35.0 bits (79), Expect = 0.83
Identities = 67/306 (21%), Positives = 110/306 (35%), Gaps = 42/306 (13%)
Query: 361 SEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILK 420
SED+ R+ +G K++I QP+++ + P +V +
Sbjct: 104 SEDKSKIVRVLNLWQKNGVFKIEIIQPLLDMAAGTSNAAPVAENVTNNEG---------- 153
Query: 421 HAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGI-------------KISSVH 467
+K S +P + P P LP A A + +I
Sbjct: 154 SPPPPVKVSS-----EPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTF 208
Query: 468 KRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLL 527
++P P+ + + AV+ A+ +A+ + +TP+ S+ PE+ A LL
Sbjct: 209 QQP-PKPQSPALDNAVM--AQVQAITAQL---KTTPTQPSEQKAAFPPPEQKTAFDKKLL 262
Query: 528 YKSTKEDRRS--EEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKK 585
+ +D EE + T P +AV PAP VP + A AAA+P +
Sbjct: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAV--PPAPTATVP---AAAAPAAASPPPPQ 317
Query: 586 PPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPS 645
P GF G ++P + + R G P + + G P P
Sbjct: 318 APFGFPGDGMQQPAYTQHQNMDQFQPRMMG-IQQDPMHHQVPLPPNGQMPGFGLLPTPPF 376
Query: 646 VPMASP 651
PMA P
Sbjct: 377 PPMAQP 382
Score = 32.3 bits (72), Expect = 5.4
Identities = 42/164 (25%), Positives = 57/164 (34%), Gaps = 34/164 (20%)
Query: 1219 QPEEADVPAYPKVA--TVPQSEKKPSKY--PLCSADAAVSTTPP----------GSPPPP 1264
+P VP P A TVP + P + P+ A + TPP G PPPP
Sbjct: 660 KPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPP 719
Query: 1265 PPLP--EP---PVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSA-----------S 1308
PP P P P+ L P P P T + T S +S
Sbjct: 720 PPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDL 779
Query: 1309 KTASPLEHILQTLFGKKKSFDP----SAREPPGSTAGLPQEPKT 1348
+P+ ++ G +S D + PP + LP P T
Sbjct: 780 SIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVT 823
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 86.3 bits (212), Expect = 3e-16
Identities = 76/255 (29%), Positives = 121/255 (47%), Gaps = 35/255 (13%)
Query: 2012 QGQAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFR 2071
Q Q +K PR + + + E S S +P + P + + R
Sbjct: 226 QKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSR--SRSHHR 283
Query: 2072 EGKGHEYRNQTFEG-RQRERFDVGPKEKPLEEPDAQG--RASEDRR---RERERGRNWSR 2125
EG G ++ E ++R+R + KE+ E ++ R E RR RER R R+ SR
Sbjct: 284 EGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSR 343
Query: 2126 ERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERS--------- 2176
+R DR R+ DR R+K++ +R R R + D+ER +R KE +RSRERS
Sbjct: 344 DRKGDR-RDRDREREKEN----ERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEV 398
Query: 2177 ------------RNRERERDRRRDRDRSRSRERDRD-KARDRERGRDRKDRSKSKESARD 2223
R+R+ +RD ++++ SRSR R+R ++R R R ++ RS+SKE +
Sbjct: 399 EEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSK 458
Query: 2224 PKPEASRASDAGTAS 2238
K E+ S+ + S
Sbjct: 459 HKNESKEKSNKRSRS 473
Score = 65.9 bits (159), Expect = 4e-10
Identities = 64/293 (21%), Positives = 122/293 (41%), Gaps = 25/293 (8%)
Query: 1960 RGIQPQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQAPQVM 2019
R ++ ++ R PR + +R+ + GS+ F + E+ R + +A +
Sbjct: 253 RHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKERE 312
Query: 2020 KPGPRPLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEAD---------GQWASADF 2070
K R + R+ R E + S G + D G+ D+
Sbjct: 313 KERRRS--RSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDY 370
Query: 2071 REGKGHEYRNQTFEGRQR--ERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERD 2128
+ +G+E + R+R E+ G E+ + D R D +R+ ++ + SR R
Sbjct: 371 DKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRS 430
Query: 2129 WDRPR----------EWDRHRDKD-SSRDWDRNRERSANRDREREADRGKEWDRSRERSR 2177
+R + R R K+ SS+ + ++E+S R R R ++S++R
Sbjct: 431 RERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREH 490
Query: 2178 NRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASR 2230
+ +E+ R+R R + RS +RD ++D+ DR+ RS+S E K ++
Sbjct: 491 SPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRR-RSQSIEQESQEKQHKNK 542
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 83.6 bits (205), Expect = 2e-15
Identities = 143/682 (20%), Positives = 225/682 (32%), Gaps = 113/682 (16%)
Query: 1614 PASSPWASGEKPPAGSEQDGWKAEPGEG---TRPATVGDSSARPARRVLLPTPPCGALQP 1670
P+ S + + P S + A P T+PAT +S P+ +
Sbjct: 16 PSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPS 75
Query: 1671 GFPLQHDGERDPFTCPGFASQDKALGSA------QYEDPRNLHSAGRSSSPAGETEGDRE 1724
P R P S D A + R HS GR+ G R
Sbjct: 76 NRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRS 135
Query: 1725 PQ--ARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFP 1782
P + PG PG P Q G G ++ PR
Sbjct: 136 PSRASTPGRIRTHGARPGMASRVRTPTSQ-----------QKGSRGKSYGRPR------T 178
Query: 1783 EENIASNDGPRGPPPARFGAQKGPIPSLFSGQHGPPPYGDSRG--------PSPSYLGGP 1834
S+ PR S + PP G G PS + P
Sbjct: 179 SNRERSDSQPRN----------------LSKKSYRPPGGSGIGRSSELAVTPSTAKCQTP 222
Query: 1835 RGVAPSQFEERKDPHGEKREFQDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRR 1894
G+ + + P R+ + + + TE + SR + Q + R
Sbjct: 223 TGIPSKEKSDNPSP-SSSRKVKSYGQMIIPSREKSYSPTE----MSSRVKSYNQASTRSR 277
Query: 1895 PLL-SQLKGPRGGPPPSQ---------------FGGQRGPPPGHFVGPRGPHPSQFETAR 1938
P SQ + PR SQ R + G H ++
Sbjct: 278 PQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSK 337
Query: 1939 GPHPNQFEGPR-GQAPNFMPGPRGIQPQQFEDQRVHSPPRFTNQR-----APAPLQFGGL 1992
G NQ PR G++ N+ P +R HS R +++ + +P + G
Sbjct: 338 GKSQNQSRTPRRGRSHNWSRNP--------SKERSHSHSRSSSKERDHRGSSSPRKESGR 389
Query: 1993 RGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSS 2052
S+ R H + ++P + R S P +DR P A
Sbjct: 390 ------SQSGSPNKQRDHSRSRSPNKARDRSR------SRSPYKARDRSRSRSPNKARDC 437
Query: 2053 SAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEK-------PLEEPDA 2105
S +A + S + + H + R R R KE+ P +E D
Sbjct: 438 SRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDH 497
Query: 2106 QGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADR 2165
+ S + R+ + R+ S+ERD R R + R + SR ++ R+RS +R E +
Sbjct: 498 RRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH 557
Query: 2166 GKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRD---RKDRSKSKESA- 2221
+ S+ER R R R + R+R +SRS +RD +R R + + R+ SKE A
Sbjct: 558 RQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAH 617
Query: 2222 ---RDPKPEASRASDAGTASQA 2240
R P E + + ++ ++
Sbjct: 618 SRSRTPSKEGNHSQSRTSSKES 639
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 83.2 bits (204), Expect = 3e-15
Identities = 58/170 (34%), Positives = 80/170 (47%), Gaps = 16/170 (9%)
Query: 2084 EGRQRERFDVGPKEKPLEEPDAQGRAS-------------EDRRRERERGRNWSRERDWD 2130
+GR+ E D K+ EE + + +S EDR + +ER + R
Sbjct: 10 QGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 69
Query: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRN-RERERDRRRDR 2189
R RE RHR + R R+R R + R R +R K RSRER R R R R R R R
Sbjct: 70 RSRE-RRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHR 128
Query: 2190 DRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGTASQ 2239
R+RSR R R ++RDR++ R K R S+ +R P P R + +Q
Sbjct: 129 HRTRSRSRTRSRSRDRKK-RIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQ 177
Score = 67.0 bits (162), Expect = 2e-10
Identities = 39/108 (36%), Positives = 59/108 (54%), Gaps = 4/108 (3%)
Query: 2118 ERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSR 2177
++GR + + + + H DK+ S D R R S+ +R + ++ R R SR
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68
Query: 2178 NRERE---RDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESAR 2222
+R RE R R R+R +SRSR R+R K+R R R R +K RS+S+E R
Sbjct: 69 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRER-KKSRSRSRERKR 115
Score = 59.7 bits (143), Expect = 3e-08
Identities = 50/189 (26%), Positives = 83/189 (43%), Gaps = 15/189 (7%)
Query: 2035 QHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVG 2094
+H D+ E L+SS G+ + S+ R R + R RER
Sbjct: 33 EHSSDKGRER-----LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER---- 83
Query: 2095 PKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERS 2154
K + + S R RER++ R+ SRER R R R R + R R+R RS
Sbjct: 84 ---KKSRSRSRERKKSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRHRTRSRSRTRS 139
Query: 2155 ANRDREREADRGKEWDRSRERSRNRE--RERDRRRDRDRSRSRERDRDKARDRERGRDRK 2212
+RDR++ ++ + + RS R+ + R R+ D + +R +R K +R ++
Sbjct: 140 RSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMV 199
Query: 2213 DRSKSKESA 2221
++ K +E A
Sbjct: 200 EKQKQQEIA 208
Score = 53.9 bits (128), Expect = 2e-06
Identities = 46/164 (28%), Positives = 68/164 (41%), Gaps = 20/164 (12%)
Query: 2074 KGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPR 2133
KG E N + G R + + ++ R R R RER ++ SR R+ + R
Sbjct: 38 KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97
Query: 2134 EWDRHRDKDSSRDWDR---------NRERSANRDREREADRGKEWDRSRERSRNRERERD 2184
R R K SR +R +R R +R R R RSR R R + E+
Sbjct: 98 SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSR------TRSRSRDRKKRIEKP 151
Query: 2185 RRRDRDRSRSRE----RDRDKARDRERGRDRK-DRSKSKESARD 2223
RR R SR+ R R+ A D + R+ +R+K + R+
Sbjct: 152 RRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQRE 195
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 82.8 bits (203), Expect = 3e-15
Identities = 129/465 (27%), Positives = 159/465 (34%), Gaps = 57/465 (12%)
Query: 1548 LPPASQASNHRDPRQARRLAAETGEGEGEPLSRLSARGAQGAL-PERDASRGGLVGQAPM 1606
+P A+ P+ R E G EG P + RG G + P A G G+
Sbjct: 751 MPGERGAAGIAGPKGDRGDVGEKGP-EGAP-GKDGGRGLTGPIGPPGPAGANGEKGEVGP 808
Query: 1607 PVPEEKEPA-SSPWASGEK----------PPAGSEQDGWKAEPGEGTRPATVGDSSARPA 1655
P P A +P GE PP Q G K E GE + G +
Sbjct: 809 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 868
Query: 1656 RRVLLPTPPCGALQPGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRSSSP 1715
P P G P G PG A + GS P P
Sbjct: 869 SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGP 928
Query: 1716 AGETEGDREPQARPGEG--TAPLPPPGQK-VGGSQPPFQGQREPGPHAL----GMSGLHG 1768
G GD P R GE P PPG+K G P + PGP L G+ GL G
Sbjct: 929 KG-ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPG 987
Query: 1769 -------PNFPGPRGPAPPFPEENIASNDGPRGP--PPARFGAQKGPIPSLFSGQHGPPP 1819
P PGP G + + GP GP PP G P G GPP
Sbjct: 988 QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG 1047
Query: 1820 YGDSRGPS-----PSYLGGPRGVAPSQFEERKDPHGEKREFQDAPYNEVTG--APAQFEG 1872
+ G +G P P P G++ + +A G PA G
Sbjct: 1048 RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1107
Query: 1873 TE--QAPFLGSRG--GAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPPPGHFVGPRG 1928
+ Q P G +G G P + G + + L+G G P PS G GP GPRG
Sbjct: 1108 IQGPQGP-RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPS--GPRG 1164
Query: 1929 P----HPSQFETARG-PHPNQFEGPRGQA-------PNFMPGPRG 1961
P PS + A G P P GPRG++ P PGP G
Sbjct: 1165 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPG 1209
Score = 74.3 bits (181), Expect = 1e-12
Identities = 119/418 (28%), Positives = 145/418 (34%), Gaps = 51/418 (12%)
Query: 1583 ARGAQG--ALPERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAG-SEQDGWKAEPG 1639
A+G QG LP + G P P + P GE+ AG + G + + G
Sbjct: 712 AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG 771
Query: 1640 EGTRPATVGDSSARPARRVLLPTPPCGA------LQPGFPLQHDGERDPFTCPGFASQDK 1693
E G R + P P GA + P P G R PG +
Sbjct: 772 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG---APGERGETG 828
Query: 1694 ALGSAQYEDPRNLHSAGRSSSPAGET--EGDREPQARPGEGTAPLPPPGQKVGGSQPPFQ 1751
G A + P + GE +GD G AP P V G +
Sbjct: 829 PPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARG 888
Query: 1752 GQREPG----PHALGMSGLHGPNF-PGPRGPAPPFPEENIASNDGPRGP-----PPARFG 1801
Q PG P A G G G N PGP GP P + DGP+G PP R G
Sbjct: 889 AQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP------SGKDGPKGARGDSGPPGRAG 942
Query: 1802 AQKGPIPSLFSGQHGPP----PYGDSRGPSPSYLGGPRGVA--PSQFEER-----KDPHG 1850
P+ G+ G P P G P P L G RG+ P Q ER P G
Sbjct: 943 EPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 1002
Query: 1851 E--KREFQDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPP 1908
E K+ A + P G R G+P G R + +KG RG
Sbjct: 1003 EPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETG 1062
Query: 1909 PSQFGGQRGPPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPGPRGIQPQQ 1966
G GPP GP GP Q + RG Q GP G P+ G RGIQ Q
Sbjct: 1063 AVGAPGAPGPPGS--PGPAGPTGKQGD--RGEAGAQ--GPMG--PSGPAGARGIQGPQ 1112
Score = 71.2 bits (173), Expect = 1e-11
Identities = 144/515 (27%), Positives = 177/515 (34%), Gaps = 99/515 (19%)
Query: 1523 PPPKSSLPKAELFQQEQQSADKPASLPPASQASNHRDPRQARRLAAETGEGEGEPLSRLS 1582
PP + P + FQ +P P R P + GE G+P +
Sbjct: 211 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP----RGPPGPPGKPGDDGEA-GKP-GKAG 264
Query: 1583 ARGAQGALPERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAGSEQ-DGWKAEPGEG 1641
RG G P+ G G +P K P G K AG+ G PGE
Sbjct: 265 ERGPPG--PQGARGFPGTPG-----LPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 317
Query: 1642 TRPATVGDSSARPARRVLLPTPPCGAL----QPGFPLQHDGERDPFTCPGFASQDKALGS 1697
P +G R P GA QPG P G P PGF A G
Sbjct: 318 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG-PAGPPGPVGPAGGPGFPGAPGAKGE 376
Query: 1698 AQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPG 1757
A + A EG + P+ PG +P P G S P
Sbjct: 377 A-------------GPTGARGPEGAQGPRGEPGTPGSPGP-----AGASGNPGTDGIPGA 418
Query: 1758 PHALGMSGLHG-PNFPGPRGPAPPFPEENIASNDGPRG----PPPARFGAQKGP--IPSL 1810
+ G G+ G P FPGPRGP P + GP+G P A F ++GP P
Sbjct: 419 KGSAGAPGIAGAPGFPGPRGPPGP---QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 475
Query: 1811 FSGQHGPPPYGD--SRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAPYNEVTGAPA 1868
Q P P G+ RG G P GV P P GE+ AP N G P
Sbjct: 476 AGPQGAPGPAGEEGKRGAR----GEPGGVGPI------GPPGER----GAPGNR--GFPG 519
Query: 1869 Q--FEGTEQAPFLGSRG--------GAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGP 1918
Q G + AP G RG GA G P L +G G P + G+ GP
Sbjct: 520 QDGLAGPKGAP--GERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 577
Query: 1919 --PPGHFVGPRGPHPSQFETARG-PHPNQFEGPRG-------QAPNFMPGPRGIQ--PQQ 1966
PG P P P + ARG P F GP+G +PG G++ P +
Sbjct: 578 SGAPGEDGRPGPPGP---QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK 634
Query: 1967 FEDQRVHSPP-------RFTNQRAPAPLQFGGLRG 1994
+ PP Q AP P F GL G
Sbjct: 635 DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG 669
Score = 69.7 bits (169), Expect = 3e-11
Identities = 148/556 (26%), Positives = 178/556 (32%), Gaps = 132/556 (23%)
Query: 1614 PASSPWASGEKPPAGSE----QDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGALQ 1669
P P G PAG+ DG G P G R P P GA
Sbjct: 391 PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG---PPGPQGATG 447
Query: 1670 PGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARP 1729
P P GE PG A G P A PAGE EG R + P
Sbjct: 448 PLGPKGQTGE------PGIAGFKGEQGPKGEPGPAGPQGA---PGPAGE-EGKRGARGEP 497
Query: 1730 GEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPN-FPGPRGPAPPFPEENIAS 1788
G G P+ PPG++ F GQ GL GP PG RGP+ +
Sbjct: 498 G-GVGPIGPPGERGAPGNRGFPGQ----------DGLAGPKGAPGERGPSGLAGPKGANG 546
Query: 1789 NDGPRGPP-----------PARFGAQKGPIPSLFSGQHGPP----PYGDSRGPSPSYLGG 1833
+ G G P P G Q PS G+ G P P G P G
Sbjct: 547 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG 606
Query: 1834 PRGV--APSQFEERKDPHGEKREFQDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGG 1891
P+G P + E+ P AP + G P + T A G G A G
Sbjct: 607 PKGANGEPGKAGEKGLP--------GAP--GLRGLPGKDGETGAAGPPGPAGPA-----G 651
Query: 1892 QRRPLLSQLKGPRGGPPPSQFGGQRGP--PPGH-----------------FVGPRGPHPS 1932
+R G +G P PS F G GP PPG VGPRG
Sbjct: 652 ER--------GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER-- 701
Query: 1933 QFETARG-PHPNQFEGPRG-------QAPNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAP 1984
F RG P +GPRG P GP G Q PP Q P
Sbjct: 702 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ-------GPPGL--QGMP 752
Query: 1985 APLQFGGLRG----SAPFSEKN-EQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKD 2039
G+ G EK E P + +G + PG P
Sbjct: 753 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG-----------PAGANG 801
Query: 2040 RWEEAGPP----SALSSSAPGQ----GPEADGQWASADFREGKGHEYRNQTFEGRQRERF 2091
E GPP SA + APG+ GP +A +G+ Q G++ +
Sbjct: 802 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861
Query: 2092 DVGPKEKPLEEPDAQG 2107
GP + P P QG
Sbjct: 862 APGP-QGPSGAPGPQG 876
Score = 54.3 bits (129), Expect = 1e-06
Identities = 92/317 (29%), Positives = 113/317 (35%), Gaps = 58/317 (18%)
Query: 1573 GEGEPLSRLSARGAQG-ALPERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPP----- 1626
G P + +GA+G + P A GL G A P E+ EP + E PP
Sbjct: 918 GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP-GEKGEPGDDGPSGAEGPPGPQGL 976
Query: 1627 AGSE----------QDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGALQPGFPLQH 1676
AG + G+ PG P G A R P P G P
Sbjct: 977 AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA----- 1031
Query: 1677 DGERDPFTCPGFASQDKALGSAQYEDPRNLHSA---------GRSSSPAGET--EGDREP 1725
GE PG G+A + R A S PAG T +GDR
Sbjct: 1032 -GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090
Query: 1726 QARPGEGTAPLPPPGQKVGGSQPPFQGQR----EPGPHAL----GMSGLHGPNFPGPRGP 1777
G P + + G Q P +G + EPG L G +GL G PGP GP
Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGP-RGDKGEAGEPGERGLKGHRGFTGLQG--LPGPPGP 1147
Query: 1778 APPFPEENIASNDGPRGP-----PPARFGAQ--KGPI----PSLFSGQHGPP-PYGDSRG 1825
+ A GPRGP P + GA GPI P SG+ GP P G+
Sbjct: 1148 SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGP 1207
Query: 1826 PSPSYLGGPRGVAPSQF 1842
P P GP G+ S F
Sbjct: 1208 PGPPGPPGP-GIDMSAF 1223
Score = 47.4 bits (111), Expect = 2e-04
Identities = 92/350 (26%), Positives = 112/350 (32%), Gaps = 102/350 (29%)
Query: 1735 PLPPPGQKVGGSQPPFQGQR-EPGPHALGMSGLHGPNFPGPRGPA--------------- 1778
P+ P QP +GQ+ EPG + G GP PGP+GPA
Sbjct: 87 PICPTDLATASGQPGPKGQKGEPGD-IKDIVGPKGP--PGPQGPAGEQGPRGDRGDKGEK 143
Query: 1779 -PPFP-----EENIASNDGPRGPP-------------------------PARFGAQKGPI 1807
P P E N GP GPP A+ G +GP+
Sbjct: 144 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 203
Query: 1808 ----------------PSLFSGQHGPP-------PYGDSRGPSPSYLGGPRGVA--PSQF 1842
P F G G P P G P P G G A P +
Sbjct: 204 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 263
Query: 1843 EERKDPHGE-KREFQDAP----------YNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGG 1891
ER P + R F P Y + GA +G AP + G+P + G
Sbjct: 264 GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGA----KGEAGAPGVKGESGSPGENGS 319
Query: 1892 QRRPLLSQLKGPRGGPPPSQFGGQRG----PPPGHFVGPRGPHPSQFETARGPHPNQFEG 1947
L G RG P+ G RG P P GP GP A GP G
Sbjct: 320 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP-------AGGPGFPGAPG 372
Query: 1948 PRGQA-PNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSA 1996
+G+A P GP G Q + E SP P G +GSA
Sbjct: 373 AKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 422
Score = 42.0 bits (97), Expect = 0.007
Identities = 69/239 (28%), Positives = 83/239 (34%), Gaps = 45/239 (18%)
Query: 1575 GEPLSRLSARGAQGALPERDASRG--------GLVGQAPMPVPEEKEPASSPWASGEKPP 1626
GEP R + GA G P RD + G G VG P P P + G P
Sbjct: 1032 GEP-GREGSPGADGP-PGRDGAAGVKGDRGETGAVGAPGAPGP--------PGSPGPAGP 1081
Query: 1627 AGSEQDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGAL-QPGFPLQHDGERDPFTC 1685
G + D GE +G S AR + P P G + G P GER
Sbjct: 1082 TGKQGDR-----GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP----GERGLKGH 1132
Query: 1686 PGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLP--PPGQKV 1743
GF G + S P G G P + G P P PPG
Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP-GPVGPSGKDGANGIPGPIGPPG--- 1188
Query: 1744 GGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIASNDGPR--GPPPARF 1800
P E GP G G GP PGP GP P + + + GPR GP P ++
Sbjct: 1189 -----PRGRSGETGP--AGPPGNPGP--PGPPGPPGPGIDMSAFAGLGPREKGPDPLQY 1238
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 82.8 bits (203), Expect = 3e-15
Identities = 129/465 (27%), Positives = 159/465 (34%), Gaps = 57/465 (12%)
Query: 1548 LPPASQASNHRDPRQARRLAAETGEGEGEPLSRLSARGAQGAL-PERDASRGGLVGQAPM 1606
+P A+ P+ R E G EG P + RG G + P A G G+
Sbjct: 682 MPGERGAAGIAGPKGDRGDVGEKGP-EGAP-GKDGGRGLTGPIGPPGPAGANGEKGEVGP 739
Query: 1607 PVPEEKEPA-SSPWASGEK----------PPAGSEQDGWKAEPGEGTRPATVGDSSARPA 1655
P P A +P GE PP Q G K E GE + G +
Sbjct: 740 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 799
Query: 1656 RRVLLPTPPCGALQPGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRSSSP 1715
P P G P G PG A + GS P P
Sbjct: 800 SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGP 859
Query: 1716 AGETEGDREPQARPGEG--TAPLPPPGQK-VGGSQPPFQGQREPGPHAL----GMSGLHG 1768
G GD P R GE P PPG+K G P + PGP L G+ GL G
Sbjct: 860 KG-ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPG 918
Query: 1769 -------PNFPGPRGPAPPFPEENIASNDGPRGP--PPARFGAQKGPIPSLFSGQHGPPP 1819
P PGP G + + GP GP PP G P G GPP
Sbjct: 919 QRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG 978
Query: 1820 YGDSRGPS-----PSYLGGPRGVAPSQFEERKDPHGEKREFQDAPYNEVTG--APAQFEG 1872
+ G +G P P P G++ + +A G PA G
Sbjct: 979 RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1038
Query: 1873 TE--QAPFLGSRG--GAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPPPGHFVGPRG 1928
+ Q P G +G G P + G + + L+G G P PS G GP GPRG
Sbjct: 1039 IQGPQGP-RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPS--GPRG 1095
Query: 1929 P----HPSQFETARG-PHPNQFEGPRGQA-------PNFMPGPRG 1961
P PS + A G P P GPRG++ P PGP G
Sbjct: 1096 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPG 1140
Score = 74.3 bits (181), Expect = 1e-12
Identities = 119/418 (28%), Positives = 145/418 (34%), Gaps = 51/418 (12%)
Query: 1583 ARGAQG--ALPERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAG-SEQDGWKAEPG 1639
A+G QG LP + G P P + P GE+ AG + G + + G
Sbjct: 643 AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG 702
Query: 1640 EGTRPATVGDSSARPARRVLLPTPPCGA------LQPGFPLQHDGERDPFTCPGFASQDK 1693
E G R + P P GA + P P G R PG +
Sbjct: 703 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG---APGERGETG 759
Query: 1694 ALGSAQYEDPRNLHSAGRSSSPAGET--EGDREPQARPGEGTAPLPPPGQKVGGSQPPFQ 1751
G A + P + GE +GD G AP P V G +
Sbjct: 760 PPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARG 819
Query: 1752 GQREPG----PHALGMSGLHGPNF-PGPRGPAPPFPEENIASNDGPRGP-----PPARFG 1801
Q PG P A G G G N PGP GP P + DGP+G PP R G
Sbjct: 820 AQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP------SGKDGPKGARGDSGPPGRAG 873
Query: 1802 AQKGPIPSLFSGQHGPP----PYGDSRGPSPSYLGGPRGVA--PSQFEER-----KDPHG 1850
P+ G+ G P P G P P L G RG+ P Q ER P G
Sbjct: 874 EPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 933
Query: 1851 E--KREFQDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPP 1908
E K+ A + P G R G+P G R + +KG RG
Sbjct: 934 EPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETG 993
Query: 1909 PSQFGGQRGPPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPGPRGIQPQQ 1966
G GPP GP GP Q + RG Q GP G P+ G RGIQ Q
Sbjct: 994 AVGAPGAPGPPGS--PGPAGPTGKQGD--RGEAGAQ--GPMG--PSGPAGARGIQGPQ 1043
Score = 71.2 bits (173), Expect = 1e-11
Identities = 144/515 (27%), Positives = 177/515 (34%), Gaps = 99/515 (19%)
Query: 1523 PPPKSSLPKAELFQQEQQSADKPASLPPASQASNHRDPRQARRLAAETGEGEGEPLSRLS 1582
PP + P + FQ +P P R P + GE G+P +
Sbjct: 142 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP----RGPPGPPGKPGDDGEA-GKP-GKAG 195
Query: 1583 ARGAQGALPERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAGSEQ-DGWKAEPGEG 1641
RG G P+ G G +P K P G K AG+ G PGE
Sbjct: 196 ERGPPG--PQGARGFPGTPG-----LPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN 248
Query: 1642 TRPATVGDSSARPARRVLLPTPPCGAL----QPGFPLQHDGERDPFTCPGFASQDKALGS 1697
P +G R P GA QPG P G P PGF A G
Sbjct: 249 GSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG-PAGPPGPVGPAGGPGFPGAPGAKGE 307
Query: 1698 AQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPG 1757
A + A EG + P+ PG +P P G S P
Sbjct: 308 A-------------GPTGARGPEGAQGPRGEPGTPGSPGP-----AGASGNPGTDGIPGA 349
Query: 1758 PHALGMSGLHG-PNFPGPRGPAPPFPEENIASNDGPRG----PPPARFGAQKGP--IPSL 1810
+ G G+ G P FPGPRGP P + GP+G P A F ++GP P
Sbjct: 350 KGSAGAPGIAGAPGFPGPRGPPGP---QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 406
Query: 1811 FSGQHGPPPYGD--SRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAPYNEVTGAPA 1868
Q P P G+ RG G P GV P P GE+ AP N G P
Sbjct: 407 AGPQGAPGPAGEEGKRGAR----GEPGGVGPI------GPPGER----GAPGNR--GFPG 450
Query: 1869 Q--FEGTEQAPFLGSRG--------GAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGP 1918
Q G + AP G RG GA G P L +G G P + G+ GP
Sbjct: 451 QDGLAGPKGAP--GERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 508
Query: 1919 --PPGHFVGPRGPHPSQFETARG-PHPNQFEGPRG-------QAPNFMPGPRGIQ--PQQ 1966
PG P P P + ARG P F GP+G +PG G++ P +
Sbjct: 509 SGAPGEDGRPGPPGP---QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK 565
Query: 1967 FEDQRVHSPP-------RFTNQRAPAPLQFGGLRG 1994
+ PP Q AP P F GL G
Sbjct: 566 DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG 600
Score = 69.7 bits (169), Expect = 3e-11
Identities = 148/556 (26%), Positives = 178/556 (32%), Gaps = 132/556 (23%)
Query: 1614 PASSPWASGEKPPAGSE----QDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGALQ 1669
P P G PAG+ DG G P G R P P GA
Sbjct: 322 PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG---PPGPQGATG 378
Query: 1670 PGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARP 1729
P P GE PG A G P A PAGE EG R + P
Sbjct: 379 PLGPKGQTGE------PGIAGFKGEQGPKGEPGPAGPQGA---PGPAGE-EGKRGARGEP 428
Query: 1730 GEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPN-FPGPRGPAPPFPEENIAS 1788
G G P+ PPG++ F GQ GL GP PG RGP+ +
Sbjct: 429 G-GVGPIGPPGERGAPGNRGFPGQ----------DGLAGPKGAPGERGPSGLAGPKGANG 477
Query: 1789 NDGPRGPP-----------PARFGAQKGPIPSLFSGQHGPP----PYGDSRGPSPSYLGG 1833
+ G G P P G Q PS G+ G P P G P G
Sbjct: 478 DPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPG 537
Query: 1834 PRGV--APSQFEERKDPHGEKREFQDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGG 1891
P+G P + E+ P AP + G P + T A G G A G
Sbjct: 538 PKGANGEPGKAGEKGLP--------GAP--GLRGLPGKDGETGAAGPPGPAGPA-----G 582
Query: 1892 QRRPLLSQLKGPRGGPPPSQFGGQRGP--PPGH-----------------FVGPRGPHPS 1932
+R G +G P PS F G GP PPG VGPRG
Sbjct: 583 ER--------GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER-- 632
Query: 1933 QFETARG-PHPNQFEGPRG-------QAPNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAP 1984
F RG P +GPRG P GP G Q PP Q P
Sbjct: 633 GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ-------GPPGL--QGMP 683
Query: 1985 APLQFGGLRG----SAPFSEKN-EQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKD 2039
G+ G EK E P + +G + PG P
Sbjct: 684 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG-----------PAGANG 732
Query: 2040 RWEEAGPP----SALSSSAPGQ----GPEADGQWASADFREGKGHEYRNQTFEGRQRERF 2091
E GPP SA + APG+ GP +A +G+ Q G++ +
Sbjct: 733 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792
Query: 2092 DVGPKEKPLEEPDAQG 2107
GP + P P QG
Sbjct: 793 APGP-QGPSGAPGPQG 807
Score = 54.3 bits (129), Expect = 1e-06
Identities = 92/317 (29%), Positives = 113/317 (35%), Gaps = 58/317 (18%)
Query: 1573 GEGEPLSRLSARGAQG-ALPERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPP----- 1626
G P + +GA+G + P A GL G A P E+ EP + E PP
Sbjct: 849 GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP-GEKGEPGDDGPSGAEGPPGPQGL 907
Query: 1627 AGSE----------QDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGALQPGFPLQH 1676
AG + G+ PG P G A R P P G P
Sbjct: 908 AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA----- 962
Query: 1677 DGERDPFTCPGFASQDKALGSAQYEDPRNLHSA---------GRSSSPAGET--EGDREP 1725
GE PG G+A + R A S PAG T +GDR
Sbjct: 963 -GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021
Query: 1726 QARPGEGTAPLPPPGQKVGGSQPPFQGQR----EPGPHAL----GMSGLHGPNFPGPRGP 1777
G P + + G Q P +G + EPG L G +GL G PGP GP
Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGP-RGDKGEAGEPGERGLKGHRGFTGLQG--LPGPPGP 1078
Query: 1778 APPFPEENIASNDGPRGP-----PPARFGAQ--KGPI----PSLFSGQHGPP-PYGDSRG 1825
+ A GPRGP P + GA GPI P SG+ GP P G+
Sbjct: 1079 SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGP 1138
Query: 1826 PSPSYLGGPRGVAPSQF 1842
P P GP G+ S F
Sbjct: 1139 PGPPGPPGP-GIDMSAF 1154
Score = 44.3 bits (103), Expect = 0.001
Identities = 90/338 (26%), Positives = 109/338 (32%), Gaps = 102/338 (30%)
Query: 1747 QPPFQGQR-EPGPHALGMSGLHGPNFPGPRGPA----------------PPFP-----EE 1784
QP +GQ+ EPG + G GP PGP+GPA P P E
Sbjct: 30 QPGPKGQKGEPGD-IKDIVGPKGP--PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86
Query: 1785 NIASNDGPRGPP-------------------------PARFGAQKGPI------------ 1807
N GP GPP A+ G +GP+
Sbjct: 87 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 146
Query: 1808 ----PSLFSGQHGPP-------PYGDSRGPSPSYLGGPRGVA--PSQFEERKDPHGE-KR 1853
P F G G P P G P P G G A P + ER P + R
Sbjct: 147 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 206
Query: 1854 EFQDAP----------YNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGP 1903
F P Y + GA +G AP + G+P + G L G
Sbjct: 207 GFPGTPGLPGVKGHRGYPGLDGA----KGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 262
Query: 1904 RGGPPPSQFGGQRG----PPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQA-PNFMPG 1958
RG P+ G RG P P GP GP A GP G +G+A P G
Sbjct: 263 RGRTGPAGAAGARGNDGQPGPAGPPGPVGP-------AGGPGFPGAPGAKGEAGPTGARG 315
Query: 1959 PRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSA 1996
P G Q + E SP P G +GSA
Sbjct: 316 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 353
Score = 42.0 bits (97), Expect = 0.007
Identities = 69/239 (28%), Positives = 83/239 (34%), Gaps = 45/239 (18%)
Query: 1575 GEPLSRLSARGAQGALPERDASRG--------GLVGQAPMPVPEEKEPASSPWASGEKPP 1626
GEP R + GA G P RD + G G VG P P P + G P
Sbjct: 963 GEP-GREGSPGADGP-PGRDGAAGVKGDRGETGAVGAPGAPGP--------PGSPGPAGP 1012
Query: 1627 AGSEQDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGAL-QPGFPLQHDGERDPFTC 1685
G + D GE +G S AR + P P G + G P GER
Sbjct: 1013 TGKQGDR-----GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP----GERGLKGH 1063
Query: 1686 PGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLP--PPGQKV 1743
GF G + S P G G P + G P P PPG
Sbjct: 1064 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP-GPVGPSGKDGANGIPGPIGPPG--- 1119
Query: 1744 GGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIASNDGPR--GPPPARF 1800
P E GP G G GP PGP GP P + + + GPR GP P ++
Sbjct: 1120 -----PRGRSGETGP--AGPPGNPGP--PGPPGPPGPGIDMSAFAGLGPREKGPDPLQY 1169
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 114,510,718
Number of Sequences: 37866
Number of extensions: 7525669
Number of successful extensions: 83328
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 679
Number of HSP's successfully gapped in prelim test: 2216
Number of HSP's that attempted gapping in prelim test: 35592
Number of HSP's gapped (non-prelim): 29463
length of query: 2240
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2122
effective length of database: 13,779,330
effective search space: 29239738260
effective search space used: 29239738260
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.