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Search of human proteins with 7019535
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019535 B-cell linker isoform 1 [Homo sapiens]
(456 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019535 B-cell linker isoform 1 [Homo sapiens] 936 0.0
gi|166235901 B-cell linker isoform 2 [Homo sapiens] 877 0.0
gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens] 143 4e-34
gi|193083221 mast cell immunoreceptor signal transducer [Homo sa... 106 4e-23
gi|38348280 SH2 domain containing 6 [Homo sapiens] 104 2e-22
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 60 5e-09
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 60 5e-09
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 60 5e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 57 3e-08
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 56 6e-08
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 56 6e-08
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 56 6e-08
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 56 6e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 54 3e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 54 3e-07
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 54 3e-07
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 54 3e-07
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 53 7e-07
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 52 1e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 52 1e-06
gi|38787970 tensin like C1 domain containing phosphatase isoform... 52 1e-06
gi|38787957 tensin like C1 domain containing phosphatase isoform... 52 1e-06
gi|38787941 tensin like C1 domain containing phosphatase isoform... 52 1e-06
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 50 3e-06
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 50 6e-06
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 49 9e-06
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 49 1e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 49 1e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 49 1e-05
gi|110349719 titin isoform N2-A [Homo sapiens] 48 2e-05
>gi|7019535 B-cell linker isoform 1 [Homo sapiens]
Length = 456
Score = 936 bits (2418), Expect = 0.0
Identities = 456/456 (100%), Positives = 456/456 (100%)
Query: 1 MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60
MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE
Sbjct: 1 MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60
Query: 61 EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI 120
EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI
Sbjct: 61 EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI 120
Query: 121 DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV 180
DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV
Sbjct: 121 DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV 180
Query: 181 PVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPA 240
PVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPA
Sbjct: 181 PVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPA 240
Query: 241 APSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ 300
APSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ
Sbjct: 241 APSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ 300
Query: 301 KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEAL 360
KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEAL
Sbjct: 301 KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEAL 360
Query: 361 HRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFG 420
HRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFG
Sbjct: 361 HRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFG 420
Query: 421 SVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS 456
SVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS
Sbjct: 421 SVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS 456
>gi|166235901 B-cell linker isoform 2 [Homo sapiens]
Length = 433
Score = 877 bits (2265), Expect = 0.0
Identities = 433/456 (94%), Positives = 433/456 (94%), Gaps = 23/456 (5%)
Query: 1 MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60
MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE
Sbjct: 1 MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60
Query: 61 EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI 120
EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI
Sbjct: 61 EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI 120
Query: 121 DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV 180
DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV
Sbjct: 121 DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV 180
Query: 181 PVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPA 240
PVEDNDENYIHPTESSSPPPEK GRNSGAWETKSPPPA
Sbjct: 181 PVEDNDENYIHPTESSSPPPEK-----------------------GRNSGAWETKSPPPA 217
Query: 241 APSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ 300
APSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ
Sbjct: 218 APSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ 277
Query: 301 KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEAL 360
KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEAL
Sbjct: 278 KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEAL 337
Query: 361 HRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFG 420
HRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFG
Sbjct: 338 HRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFG 397
Query: 421 SVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS 456
SVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS
Sbjct: 398 SVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS 433
>gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]
Length = 533
Score = 143 bits (360), Expect = 4e-34
Identities = 135/502 (26%), Positives = 192/502 (38%), Gaps = 99/502 (19%)
Query: 1 MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60
+ K K+ VP KL Q +I NE ++ P VPR +ES ++
Sbjct: 54 IQKFPKLRVPILSKLSQ------EINKNEE------RRSIFTRKPQVPRFPEETESHEED 101
Query: 61 EEQWSDDFDSDYENPDEHSDSEM---YVMPAEENA-----DDSYEPPPVEQET---RPVH 109
WS + DYE+P++ D E Y P EE D YEPPP E +
Sbjct: 102 NGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSIL 161
Query: 110 PALPFARGE--YIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPK 167
PA PF YID PP KT P +P P ++ P P PP+
Sbjct: 162 PAKPFPNSNSMYIDR-------PPSGKT-PQQPPVPPQRPMAALPPPPAGRNHSPLPPPQ 213
Query: 168 PK----GLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGT 223
+ +P D + P + S P ++ P P S P+ P G
Sbjct: 214 TNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR 273
Query: 224 ASGRNSGAWETKSPPPAAP-----SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIP- 277
+ G + + PP SPLP GKKP P ++N ++P+P
Sbjct: 274 SLGEHLPKIQKPPLPPTTERHERSSPLP--GKKPPVPKHGWGPDRRENDEDDVHQRPLPQ 331
Query: 278 -------------------------------AERHRGSSHRQEAVQSPVF-------PPA 299
A SS Q A P F PP
Sbjct: 332 PALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPI 391
Query: 300 QKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEA 359
+ + P+PLP +P +E L + WY R AE A
Sbjct: 392 RAEGRNFPLPLPNKPRPPSPA----------------EEENSLNEEWYVSYITRPEAEAA 435
Query: 360 LHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYF 419
L + N+DG+FL+R SS + PY L+V + +VYNI +R+ + ++ Y LG G+E F
Sbjct: 436 LRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDF 495
Query: 420 GSVAEIIRNHQHSPLVLIDSQN 441
SV++II + PL+LID +N
Sbjct: 496 LSVSDIIDYFRKMPLLLIDGKN 517
>gi|193083221 mast cell immunoreceptor signal transducer [Homo
sapiens]
Length = 428
Score = 106 bits (265), Expect = 4e-23
Identities = 101/389 (25%), Positives = 160/389 (41%), Gaps = 76/389 (19%)
Query: 88 AEENADDSYEPPPVEQETR----PVHPALPFARGEYIDNR----SSQRHSPPFSKTLPS- 138
A+ ++DD Y+ P + E + PA P EY D + P ++T S
Sbjct: 61 AKGHSDDDYDDPELRMEETWQSIKILPARPIKESEYADTHYFKVAMDTPLPLDTRTSISI 120
Query: 139 -KPSW-----------PSEKARLTSTLPALTALQKPQVP-PKPKGLLEDEADYVVPVEDN 185
+P+W P K + + +++K ++P P P+ L+ Y
Sbjct: 121 GQPTWNTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLPPPRPLITLPKKY------- 173
Query: 186 DENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRN-SGAWETKSPPPAAPSP 244
+ P SS PP + R T P P S R+ S E +
Sbjct: 174 --QPLPPEPESSRPP----LSQRHTFPEVQRM---PSQISLRDLSEVLEAEK-------- 216
Query: 245 LPRAGKKPTTPLKTTPVASQQNASSV----------CEEKPIPAERHRGSSHRQEAVQSP 294
+P +KP ++T + QN + + HRG Q
Sbjct: 217 VPHNQRKP----ESTHLLENQNTQEIPLAISSSSFTTSNHSVQNRDHRGGM--QPCSPQR 270
Query: 295 VFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRK 354
PPA H+ +P ++T P P S + E WY G R+
Sbjct: 271 CQPPASCSPHENILPY-KYTSWRPP-----FPKRSDRKDVQHNE-------WYIGEYSRQ 317
Query: 355 SAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKN 414
+ EEA + NKDGSFL+R S ++PY L VF+ +VYN+ +RF+E +Q+ALG
Sbjct: 318 AVEEAFMKENKDGSFLVRDCSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFALGTGLR 377
Query: 415 GEEYFGSVAEIIRNHQHSPLVLIDSQNNT 443
G+E F SV +II ++++ P++LID ++ T
Sbjct: 378 GDEKFDSVEDIIEHYKNFPIILIDGKDKT 406
>gi|38348280 SH2 domain containing 6 [Homo sapiens]
Length = 175
Score = 104 bits (259), Expect = 2e-22
Identities = 52/132 (39%), Positives = 83/132 (62%), Gaps = 2/132 (1%)
Query: 325 LPSFS-SNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPY 383
LPS + + S + +++ +L +PWY+G CDR + E AL KDG++ +R SSG QP+
Sbjct: 43 LPSVAPTGSASAAEDSDLLTQPWYSGNCDRYAVESALLHLQKDGAYTVRPSSGPHGSQPF 102
Query: 384 TLVVFFNKRVYNIPVRFIEATKQYALGRK-KNGEEYFGSVAEIIRNHQHSPLVLIDSQNN 442
TL V RV+NIP+R ++ + YALGR+ +N EE F SVA ++++ PL L+D +
Sbjct: 103 TLAVLLRGRVFNIPIRRLDGGRHYALGREGRNREELFSSVAAMVQHFMWHPLPLVDRHSG 162
Query: 443 TKDSTRLKYAVK 454
+++ T L + K
Sbjct: 163 SRELTCLLFPTK 174
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 59.7 bits (143), Expect = 5e-09
Identities = 78/339 (23%), Positives = 128/339 (37%), Gaps = 32/339 (9%)
Query: 10 PASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFD 69
P RQ +K+ D + + K K ++ P S E + + +D+
Sbjct: 89 PLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE----GEGESSDSRSVNDEGS 144
Query: 70 SDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHS 129
SD ++ D+ + S +P+ ++ + + +Q + PAL G + +
Sbjct: 145 SDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV----TPAPSSA 200
Query: 130 PPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVP-VEDNDEN 188
PP + LP+ PS A P TA Q P P P + P +
Sbjct: 201 PPGTPQLPTPGPTPSATAVPPQGSP--TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 258
Query: 189 YIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPP----PAAPSP 244
HP SP P P+ + +P++ + A PP G G ++ P P P P
Sbjct: 259 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG-PPGPHSLQAGPLLQHPGPPQP 317
Query: 245 --LPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQ 302
LP + PL T+P A+ + S +PA + S +Q + P+ P
Sbjct: 318 FGLPPQASQGQAPLGTSPAAAYPHTS-----LQLPASQSALQS-QQPPREQPLPPAPLAM 371
Query: 303 IHQKP---IPLPRF----TEGGNPTVDGPLPSFSSNSTI 334
H KP P+P+ P + GP P FS N+ +
Sbjct: 372 PHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANL 409
Score = 44.7 bits (104), Expect = 2e-04
Identities = 66/292 (22%), Positives = 99/292 (33%), Gaps = 47/292 (16%)
Query: 126 QRHSPPFSKTLPSKP-SWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVED 184
Q PP + LP P + P K T+ +P L A Q + PP G + +P
Sbjct: 354 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 413
Query: 185 -----NDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGT----------ASGRNS 229
+ + HP + PP + P ++P S+PA PPG AS +
Sbjct: 414 ALKPLSSLSTHHPPSAHPPPLQLMPQ----SQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469
Query: 230 GAWETKSPPPAAPSPLPRAGKKPTTP-----LKTTPVASQQNASSVCEEKPIPAERHRGS 284
G + PP A P G P TP T P +A C G
Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 529
Query: 285 SH--------RQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISE 336
S ++EA+ P + P P PR VD P + S
Sbjct: 530 SSCPLPTVQIKEEALDDAEEP-------ESPPPPPRSPSPEPTVVDTPSHASQSARFYKH 582
Query: 337 QEAGV-------LCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQ 381
+ G L AG+ K EEA+ ++ ++ R+ + ++
Sbjct: 583 LDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEK 634
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 59.7 bits (143), Expect = 5e-09
Identities = 78/339 (23%), Positives = 128/339 (37%), Gaps = 32/339 (9%)
Query: 10 PASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFD 69
P RQ +K+ D + + K K ++ P S E + + +D+
Sbjct: 643 PLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE----GEGESSDSRSVNDEGS 698
Query: 70 SDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHS 129
SD ++ D+ + S +P+ ++ + + +Q + PAL G + +
Sbjct: 699 SDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV----TPAPSSA 754
Query: 130 PPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVP-VEDNDEN 188
PP + LP+ PS A P TA Q P P P + P +
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQGSP--TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812
Query: 189 YIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPP----PAAPSP 244
HP SP P P+ + +P++ + A PP G G ++ P P P P
Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG-PPGPHSLQAGPLLQHPGPPQP 871
Query: 245 --LPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQ 302
LP + PL T+P A+ + S +PA + S +Q + P+ P
Sbjct: 872 FGLPPQASQGQAPLGTSPAAAYPHTS-----LQLPASQSALQS-QQPPREQPLPPAPLAM 925
Query: 303 IHQKP---IPLPRF----TEGGNPTVDGPLPSFSSNSTI 334
H KP P+P+ P + GP P FS N+ +
Sbjct: 926 PHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANL 963
Score = 44.7 bits (104), Expect = 2e-04
Identities = 66/292 (22%), Positives = 99/292 (33%), Gaps = 47/292 (16%)
Query: 126 QRHSPPFSKTLPSKP-SWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVED 184
Q PP + LP P + P K T+ +P L A Q + PP G + +P
Sbjct: 908 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 967
Query: 185 -----NDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGT----------ASGRNS 229
+ + HP + PP + P ++P S+PA PPG AS +
Sbjct: 968 ALKPLSSLSTHHPPSAHPPPLQLMPQ----SQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023
Query: 230 GAWETKSPPPAAPSPLPRAGKKPTTP-----LKTTPVASQQNASSVCEEKPIPAERHRGS 284
G + PP A P G P TP T P +A C G
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083
Query: 285 SH--------RQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISE 336
S ++EA+ P + P P PR VD P + S
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEP-------ESPPPPPRSPSPEPTVVDTPSHASQSARFYKH 1136
Query: 337 QEAGV-------LCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQ 381
+ G L AG+ K EEA+ ++ ++ R+ + ++
Sbjct: 1137 LDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEK 1188
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 59.7 bits (143), Expect = 5e-09
Identities = 78/339 (23%), Positives = 128/339 (37%), Gaps = 32/339 (9%)
Query: 10 PASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFD 69
P RQ +K+ D + + K K ++ P S E + + +D+
Sbjct: 643 PLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSE----GEGESSDSRSVNDEGS 698
Query: 70 SDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHS 129
SD ++ D+ + S +P+ ++ + + +Q + PAL G + +
Sbjct: 699 SDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGV----TPAPSSA 754
Query: 130 PPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVP-VEDNDEN 188
PP + LP+ PS A P TA Q P P P + P +
Sbjct: 755 PPGTPQLPTPGPTPSATAVPPQGSP--TASQAPNQPQAPTAPVPHTHIQQAPALHPQRPP 812
Query: 189 YIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPP----PAAPSP 244
HP SP P P+ + +P++ + A PP G G ++ P P P P
Sbjct: 813 SPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG-PPGPHSLQAGPLLQHPGPPQP 871
Query: 245 --LPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQ 302
LP + PL T+P A+ + S +PA + S +Q + P+ P
Sbjct: 872 FGLPPQASQGQAPLGTSPAAAYPHTS-----LQLPASQSALQS-QQPPREQPLPPAPLAM 925
Query: 303 IHQKP---IPLPRF----TEGGNPTVDGPLPSFSSNSTI 334
H KP P+P+ P + GP P FS N+ +
Sbjct: 926 PHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANL 963
Score = 44.7 bits (104), Expect = 2e-04
Identities = 66/292 (22%), Positives = 99/292 (33%), Gaps = 47/292 (16%)
Query: 126 QRHSPPFSKTLPSKP-SWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVED 184
Q PP + LP P + P K T+ +P L A Q + PP G + +P
Sbjct: 908 QSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP 967
Query: 185 -----NDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGT----------ASGRNS 229
+ + HP + PP + P ++P S+PA PPG AS +
Sbjct: 968 ALKPLSSLSTHHPPSAHPPPLQLMPQ----SQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023
Query: 230 GAWETKSPPPAAPSPLPRAGKKPTTP-----LKTTPVASQQNASSVCEEKPIPAERHRGS 284
G + PP A P G P TP T P +A C G
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083
Query: 285 SH--------RQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISE 336
S ++EA+ P + P P PR VD P + S
Sbjct: 1084 SSCPLPTVQIKEEALDDAEEP-------ESPPPPPRSPSPEPTVVDTPSHASQSARFYKH 1136
Query: 337 QEAGV-------LCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQ 381
+ G L AG+ K EEA+ ++ ++ R+ + ++
Sbjct: 1137 LDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEK 1188
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 57.0 bits (136), Expect = 3e-08
Identities = 71/277 (25%), Positives = 103/277 (37%), Gaps = 29/277 (10%)
Query: 98 PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLT--STLPA 155
PPP E P+ AL +R S P S S P P E++ L+ P
Sbjct: 469 PPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPP 528
Query: 156 LTALQKPQVPPKPKGLLE---DEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKP 212
AL+ P PP L +E+ P E+ + SPPPE++PM + P
Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPM----SPP 584
Query: 213 NSSTPASPPGTASGRNSGAWETKSPPPAAPSPL--PRAGKKPTTPLKTTPVASQQNAS-- 268
+P SPP AS E+ PP SPL P + + P + +P++ S
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPM 644
Query: 269 ----SVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKP------IPLPRFTEGGN 318
V P+P S +SP+ PP ++ P P P +
Sbjct: 645 SPPPEVSRLSPLPVV----SRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP 700
Query: 319 PTVDGPL--PSFSSNSTISEQEAGVLCKPWYAGACDR 353
P D P P S ++ +E+ +L P C R
Sbjct: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR 737
Score = 52.8 bits (125), Expect = 7e-07
Identities = 74/280 (26%), Positives = 98/280 (35%), Gaps = 31/280 (11%)
Query: 45 PSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQE 104
P P + + SP E +S +S P+E S P + S PP E+
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552
Query: 105 T-RPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKP-SWPSEKARLTSTLPALTALQKP 162
P LP + S P S P S P E +RL + P
Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE-----ESP 607
Query: 163 QVPPKPKGLLED--EADYVVPVEDNDENYIHPTESS-SPPPEKA-----PMVNRSTKPNS 214
PP + L EA + P ++ P ES SPPPE + P+V+R + P
Sbjct: 608 LSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPE 667
Query: 215 STPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSV---- 270
+P SPP S SPPP A P PT+P AS S+
Sbjct: 668 ESPLSPPPEES--------PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLP 719
Query: 271 CEEKP-IPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 309
EE P +P R E P P ++ H P P
Sbjct: 720 LEESPLLPLPEEPQLCPRSE---GPHLSPRPEEPHLSPRP 756
Score = 45.1 bits (105), Expect = 1e-04
Identities = 59/243 (24%), Positives = 97/243 (39%), Gaps = 28/243 (11%)
Query: 115 ARGEYIDNRSSQRHSPPFSKTLPSKPS-WPSEK--------------ARLTSTLPALTAL 159
A+G +++H+P S+ P +P P+++ +TS P
Sbjct: 352 AQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGP 411
Query: 160 QKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESS-SPPPEKAPM-----VNRSTKPN 213
+ + P K ++ E P+ + P ES SPPPE++P +R + P
Sbjct: 412 LQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPP 471
Query: 214 SSTPASPPGTASGRNSGAWETKSPPPAAPSPL-PRAGKKPTTPLKTTPVA-SQQNASSVC 271
PASP A + E+ PP SPL P P +PL+ +P++ +++ S
Sbjct: 472 EELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPA 531
Query: 272 EEKPI--PAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFS 329
E P+ P E S +E SP+ PP ++ P R + + P P S
Sbjct: 532 LETPLSPPPEASPLSPPFEE---SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588
Query: 330 SNS 332
S
Sbjct: 589 PMS 591
Score = 33.1 bits (74), Expect = 0.54
Identities = 57/233 (24%), Positives = 83/233 (35%), Gaps = 34/233 (14%)
Query: 69 DSDYENPDEHSDSEMYVMPAEE-NADDSYEPPPV---EQETRPVHPALPFARGEYIDNRS 124
DSD E+P E + P E N D PP+ PV PA P +
Sbjct: 966 DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPI-----LMEPL 1020
Query: 125 SQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGL-LEDEAD-YVVPV 182
+ SP +L + S PS+ + PAL + P K + + DEA+ + +
Sbjct: 1021 PPQCSPLLQHSLVPQNSPPSQ-----CSPPALPLSVPSPLSPIGKVVGVSDEAELHEMET 1075
Query: 183 EDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAP 242
E E E S+ P +PM + S S PA + G ++ + P + P
Sbjct: 1076 EKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQP 1135
Query: 243 SPLPRAGK-----------------KPTTPLKTTPVASQ-QNASSVCEEKPIP 277
P G P TP++ P Q S CEE+ P
Sbjct: 1136 EPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEP 1188
Score = 32.7 bits (73), Expect = 0.70
Identities = 36/118 (30%), Positives = 40/118 (33%), Gaps = 13/118 (11%)
Query: 131 PFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPK---PKGLLEDEADYVVPVEDNDE 187
P L +P T L L A +PQ PP+ P G L + PV
Sbjct: 4252 PLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALST-GPVLGPV----- 4305
Query: 188 NYIHPTESSSPPPE-KAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSP 244
HPT S P E K P S T A P T G T PPP SP
Sbjct: 4306 ---HPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSP 4360
Score = 29.6 bits (65), Expect = 5.9
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 21/103 (20%)
Query: 149 LTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNR 208
L S L L+ L++ P+P + Y V + D + S+PPPE+ +
Sbjct: 4869 LKSQLDILSLLKQESPAPEPP----TQHSYTYNVSNLDVRQL-----SAPPPEEP---SP 4916
Query: 209 STKPNSSTPASPPGTASGRNSGAWETKSPP---PAAPSPLPRA 248
P + +PASPP E + P P PSPLP A
Sbjct: 4917 PPSPLAPSPASPP------TEPLVELPTEPLAEPPVPSPLPLA 4953
Score = 29.6 bits (65), Expect = 5.9
Identities = 24/105 (22%), Positives = 35/105 (33%), Gaps = 12/105 (11%)
Query: 208 RSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSP-----LPRAGKKPTTPLKTTPVA 262
+ P P T + N + +PPP PSP P PT PL P
Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELP-- 4937
Query: 263 SQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKP 307
+ E P+P+ SS + PP + + + P
Sbjct: 4938 -----TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 56.2 bits (134), Expect = 6e-08
Identities = 59/209 (28%), Positives = 80/209 (38%), Gaps = 47/209 (22%)
Query: 81 SEMYVMPAEENADDSYEPPPVEQ-----ETRPVHPALPFARGEYIDNRSSQRHS------ 129
SE+ E +EPPP + +P+ + A G I+NR +
Sbjct: 261 SELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG-LIENRPQSPATGRTPVF 319
Query: 130 -----PPFSKTLPSKPSWPSEKARLTSTLPA---------LTALQKPQVPPKPKGLLEDE 175
PP LPS S S +A +TST P TALQ P VPP P L
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL---- 375
Query: 176 ADYVVPVEDNDENYIHPTESSSPPP--EKAPMVNRSTKPNSSTPASPPGTASGRNSGAWE 233
+ P +HP PP + +P V R+ + P P G G
Sbjct: 376 --QIAP------GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHP--LPQGEVQGL-- 423
Query: 234 TKSPPPAAPSPLPRAGKKPTTPLKTTPVA 262
PPP P PLP G +P++P+ T +A
Sbjct: 424 ---PPPPPPPPLPPPGIRPSSPVTVTALA 449
Score = 36.2 bits (82), Expect = 0.063
Identities = 40/175 (22%), Positives = 54/175 (30%), Gaps = 22/175 (12%)
Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPA 218
L +P PP P + +P + + SP + P+ T P P
Sbjct: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPL 331
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPA 278
P S + A T +PPP P P P P P A Q A V P P
Sbjct: 332 --PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP- 388
Query: 279 ERHRGSSHRQEAVQSPVFPPAQKQIHQKPI-------PLPRFTEGGNPTVDGPLP 326
+ P+ P+ P+ PLP+ G P P P
Sbjct: 389 ------------IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPP 431
Score = 35.4 bits (80), Expect = 0.11
Identities = 34/137 (24%), Positives = 51/137 (37%), Gaps = 13/137 (9%)
Query: 87 PAEENADDSYEPPPVEQETRP--VHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPS 144
PA + PPP + P +HPA P + + P +T+P P
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418
Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
E L P PP P + + V + + +HPT S++P P P
Sbjct: 419 EVQGLPPP---------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPH-VP 468
Query: 205 MVNRSTKPNSSTPASPP 221
++ S P+ PAS P
Sbjct: 469 LMPPS-PPSQVIPASEP 484
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 56.2 bits (134), Expect = 6e-08
Identities = 59/209 (28%), Positives = 80/209 (38%), Gaps = 47/209 (22%)
Query: 81 SEMYVMPAEENADDSYEPPPVEQ-----ETRPVHPALPFARGEYIDNRSSQRHS------ 129
SE+ E +EPPP + +P+ + A G I+NR +
Sbjct: 261 SELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG-LIENRPQSPATGRTPVF 319
Query: 130 -----PPFSKTLPSKPSWPSEKARLTSTLPA---------LTALQKPQVPPKPKGLLEDE 175
PP LPS S S +A +TST P TALQ P VPP P L
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL---- 375
Query: 176 ADYVVPVEDNDENYIHPTESSSPPP--EKAPMVNRSTKPNSSTPASPPGTASGRNSGAWE 233
+ P +HP PP + +P V R+ + P P G G
Sbjct: 376 --QIAP------GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHP--LPQGEVQGL-- 423
Query: 234 TKSPPPAAPSPLPRAGKKPTTPLKTTPVA 262
PPP P PLP G +P++P+ T +A
Sbjct: 424 ---PPPPPPPPLPPPGIRPSSPVTVTALA 449
Score = 36.2 bits (82), Expect = 0.063
Identities = 40/175 (22%), Positives = 54/175 (30%), Gaps = 22/175 (12%)
Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPA 218
L +P PP P + +P + + SP + P+ T P P
Sbjct: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPL 331
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPA 278
P S + A T +PPP P P P P P A Q A V P P
Sbjct: 332 --PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP- 388
Query: 279 ERHRGSSHRQEAVQSPVFPPAQKQIHQKPI-------PLPRFTEGGNPTVDGPLP 326
+ P+ P+ P+ PLP+ G P P P
Sbjct: 389 ------------IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPP 431
Score = 35.4 bits (80), Expect = 0.11
Identities = 34/137 (24%), Positives = 51/137 (37%), Gaps = 13/137 (9%)
Query: 87 PAEENADDSYEPPPVEQETRP--VHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPS 144
PA + PPP + P +HPA P + + P +T+P P
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418
Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
E L P PP P + + V + + +HPT S++P P P
Sbjct: 419 EVQGLPPP---------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPH-VP 468
Query: 205 MVNRSTKPNSSTPASPP 221
++ S P+ PAS P
Sbjct: 469 LMPPS-PPSQVIPASEP 484
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 56.2 bits (134), Expect = 6e-08
Identities = 59/209 (28%), Positives = 80/209 (38%), Gaps = 47/209 (22%)
Query: 81 SEMYVMPAEENADDSYEPPPVEQ-----ETRPVHPALPFARGEYIDNRSSQRHS------ 129
SE+ E +EPPP + +P+ + A G I+NR +
Sbjct: 261 SELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG-LIENRPQSPATGRTPVF 319
Query: 130 -----PPFSKTLPSKPSWPSEKARLTSTLPA---------LTALQKPQVPPKPKGLLEDE 175
PP LPS S S +A +TST P TALQ P VPP P L
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL---- 375
Query: 176 ADYVVPVEDNDENYIHPTESSSPPP--EKAPMVNRSTKPNSSTPASPPGTASGRNSGAWE 233
+ P +HP PP + +P V R+ + P P G G
Sbjct: 376 --QIAP------GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHP--LPQGEVQGL-- 423
Query: 234 TKSPPPAAPSPLPRAGKKPTTPLKTTPVA 262
PPP P PLP G +P++P+ T +A
Sbjct: 424 ---PPPPPPPPLPPPGIRPSSPVTVTALA 449
Score = 36.2 bits (82), Expect = 0.063
Identities = 40/175 (22%), Positives = 54/175 (30%), Gaps = 22/175 (12%)
Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPA 218
L +P PP P + +P + + SP + P+ T P P
Sbjct: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPL 331
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPA 278
P S + A T +PPP P P P P P A Q A V P P
Sbjct: 332 --PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP- 388
Query: 279 ERHRGSSHRQEAVQSPVFPPAQKQIHQKPI-------PLPRFTEGGNPTVDGPLP 326
+ P+ P+ P+ PLP+ G P P P
Sbjct: 389 ------------IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPP 431
Score = 35.4 bits (80), Expect = 0.11
Identities = 34/137 (24%), Positives = 51/137 (37%), Gaps = 13/137 (9%)
Query: 87 PAEENADDSYEPPPVEQETRP--VHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPS 144
PA + PPP + P +HPA P + + P +T+P P
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418
Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
E L P PP P + + V + + +HPT S++P P P
Sbjct: 419 EVQGLPPP---------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPH-VP 468
Query: 205 MVNRSTKPNSSTPASPP 221
++ S P+ PAS P
Sbjct: 469 LMPPS-PPSQVIPASEP 484
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 56.2 bits (134), Expect = 6e-08
Identities = 59/209 (28%), Positives = 80/209 (38%), Gaps = 47/209 (22%)
Query: 81 SEMYVMPAEENADDSYEPPPVEQ-----ETRPVHPALPFARGEYIDNRSSQRHS------ 129
SE+ E +EPPP + +P+ + A G I+NR +
Sbjct: 261 SELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG-LIENRPQSPATGRTPVF 319
Query: 130 -----PPFSKTLPSKPSWPSEKARLTSTLPA---------LTALQKPQVPPKPKGLLEDE 175
PP LPS S S +A +TST P TALQ P VPP P L
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL---- 375
Query: 176 ADYVVPVEDNDENYIHPTESSSPPP--EKAPMVNRSTKPNSSTPASPPGTASGRNSGAWE 233
+ P +HP PP + +P V R+ + P P G G
Sbjct: 376 --QIAP------GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHP--LPQGEVQGL-- 423
Query: 234 TKSPPPAAPSPLPRAGKKPTTPLKTTPVA 262
PPP P PLP G +P++P+ T +A
Sbjct: 424 ---PPPPPPPPLPPPGIRPSSPVTVTALA 449
Score = 36.2 bits (82), Expect = 0.063
Identities = 40/175 (22%), Positives = 54/175 (30%), Gaps = 22/175 (12%)
Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPA 218
L +P PP P + +P + + SP + P+ T P P
Sbjct: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPL 331
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPA 278
P S + A T +PPP P P P P P A Q A V P P
Sbjct: 332 --PSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP- 388
Query: 279 ERHRGSSHRQEAVQSPVFPPAQKQIHQKPI-------PLPRFTEGGNPTVDGPLP 326
+ P+ P+ P+ PLP+ G P P P
Sbjct: 389 ------------IAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPP 431
Score = 35.4 bits (80), Expect = 0.11
Identities = 34/137 (24%), Positives = 51/137 (37%), Gaps = 13/137 (9%)
Query: 87 PAEENADDSYEPPPVEQETRP--VHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPS 144
PA + PPP + P +HPA P + + P +T+P P
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418
Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
E L P PP P + + V + + +HPT S++P P P
Sbjct: 419 EVQGLPPP---------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPH-VP 468
Query: 205 MVNRSTKPNSSTPASPP 221
++ S P+ PAS P
Sbjct: 469 LMPPS-PPSQVIPASEP 484
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 53.9 bits (128), Expect = 3e-07
Identities = 55/242 (22%), Positives = 88/242 (36%), Gaps = 31/242 (12%)
Query: 123 RSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQ--VPPKPKGLLEDEAD--Y 178
++S + P SK L P+ KA T+ PALT ++P P +P E
Sbjct: 181 KTSAKDLAPTSKVLAK----PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 236
Query: 179 VVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPP 238
+ + T S+P K P + +P +TP P T + + TKS P
Sbjct: 237 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT-KEPAPTTTKSAP 295
Query: 239 PAAPSPLPRAGKKP----------TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQ 288
P P KKP TTP + TP ++ A + E P + ++ ++
Sbjct: 296 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 355
Query: 289 EAVQSPVFPPAQKQIHQKPI------------PLPRFTEGGNPTVDGPLPSFSSNSTISE 336
A +P P P P P T+ T P P+ + ++ +
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
Query: 337 QE 338
+E
Sbjct: 416 KE 417
Score = 52.8 bits (125), Expect = 7e-07
Identities = 52/199 (26%), Positives = 73/199 (36%), Gaps = 18/199 (9%)
Query: 97 EPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPAL 156
EP P ++ P P P ++ + P + P+ P+ P E A T PA
Sbjct: 402 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPAP 460
Query: 157 TALQKPQ--VPPKPKGLLEDEADYVVP--VEDNDENYIHPTESSSPPPEKAPMVNRSTKP 212
T +KP P +P E P + + PT P P P T P
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTP 519
Query: 213 NSSTPASP--PGTASGRNSGAWETKSPPPAAPS-PLPRAGKKP--TTPLKTTPVASQQNA 267
TP +P P + + + K P P P P P K+P TTP +T P + A
Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579
Query: 268 SSVCEE-------KPIPAE 279
+ +E KP P E
Sbjct: 580 PTTLKEPAPTTPKKPAPKE 598
Score = 48.5 bits (114), Expect = 1e-05
Identities = 49/186 (26%), Positives = 63/186 (33%), Gaps = 29/186 (15%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPS--WPS 144
P E EP P +E P P P + T P KP+ P
Sbjct: 322 PKEPTPTTPKEPAPTTKEPAPTTPKEP-------------------APTAPKKPAPTTPK 362
Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
E A T PA T ++P P PK E + T S+P K P
Sbjct: 363 EPAPTTPKEPAPTTTKEPS-PTTPK---EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418
Query: 205 MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPS-PLPRAGKK--PTTPLKTTPV 261
+ +P +TP P T + K P P P P P KK PTTP + P
Sbjct: 419 SPTTTKEPAPTTPKEPAPTTP-KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477
Query: 262 ASQQNA 267
++ A
Sbjct: 478 TPKETA 483
Score = 48.1 bits (113), Expect = 2e-05
Identities = 56/234 (23%), Positives = 87/234 (37%), Gaps = 21/234 (8%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P E + EP P ++ P P P + + +P +K P+ P E
Sbjct: 221 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE--PAPTTPKEP 278
Query: 147 ARLTSTLPALTALQK-PQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPM 205
A T+ PA T + P P +P + P E PT ++ P E AP
Sbjct: 279 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPT 336
Query: 206 VNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAP-SPLPRAGKK--PTTP------- 255
+P +TP P TA + K P P P P P K+ PTTP
Sbjct: 337 TK---EPAPTTPKEPAPTAP-KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 392
Query: 256 LKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 309
K+ P +++ A + + P + ++ ++ A +P P +KP P
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP--KKPAP 444
Score = 46.6 bits (109), Expect = 5e-05
Identities = 50/211 (23%), Positives = 77/211 (36%), Gaps = 9/211 (4%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P E + EP P ++ P P P ++ + P + P+ P+ P E
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEP 333
Query: 147 ARLTSTLPALTALQKPQ--VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
A T PA T ++P P KP E P E P S + P E AP
Sbjct: 334 APTTKE-PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP--SPTTPKEPAP 390
Query: 205 MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQ 264
+S + PA P T + E P+P PTTP K P +
Sbjct: 391 TTTKSAPTTTKEPA--PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 448
Query: 265 QNASSVCEE-KPIPAERHRGSSHRQEAVQSP 294
+ A + +E P ++ ++ ++ A +P
Sbjct: 449 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 479
Score = 45.1 bits (105), Expect = 1e-04
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 11/151 (7%)
Query: 135 TLPSKPSWPSEKARLTSTL--PALTALQKPQ----VPPKPKGLLEDEADYVVPVEDNDEN 188
T P +P+ + K +TL PA T +KP P KG +D P +
Sbjct: 634 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 693
Query: 189 YIHPTESSSPPPEK-APMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPR 247
P E + P+K AP + P +S ++P T +S P + P P+
Sbjct: 694 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 753
Query: 248 A----GKKPTTPLKTTPVASQQNASSVCEEK 274
A K+P P TP A++ ++ ++K
Sbjct: 754 ALENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/240 (24%), Positives = 82/240 (34%), Gaps = 27/240 (11%)
Query: 99 PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTA 158
P +E P P P ++ + + P + P+ P+ P E A T PA T
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTT 566
Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPA 218
K P PKG P T P E AP +TK +ST
Sbjct: 567 -PKETAPTTPKGTAPTTLKEPAPT----------TPKKPAPKELAPT---TTKEPTSTTC 612
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPA 278
P + + + K P P P PTTP T P ++ A + +KP P
Sbjct: 613 DKPAPTTPKGTAPTTPKEPAPTTPKE-----PAPTTPKGTAPTTLKEPAPTT-PKKPAPK 666
Query: 279 E----RHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTV-DGPLPSFSSNST 333
E +G + +P P K P P + PT + P P+ S ST
Sbjct: 667 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-PAPTTPKKPAPTTPETPPPTTSEVST 725
Score = 40.0 bits (92), Expect = 0.004
Identities = 47/188 (25%), Positives = 69/188 (36%), Gaps = 23/188 (12%)
Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDE-----NY 189
T P KP+ P E A T+ P T KP P PKG P +
Sbjct: 589 TTPKKPA-PKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 646
Query: 190 IHPTESSSPPP----EKAP--MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPS 243
PT P P + AP + +TK +ST + P + + + K P P P
Sbjct: 647 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 706
Query: 244 -PLPRAGKKP--TTPLKTTPVASQQNAS-------SVCEEKPIPAERHRGSSHRQEAVQS 293
P P + P TT +TP +++ + S E P + +S ++ V +
Sbjct: 707 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 766
Query: 294 PVFPPAQK 301
P A K
Sbjct: 767 TKTPAATK 774
Score = 37.0 bits (84), Expect = 0.037
Identities = 50/246 (20%), Positives = 87/246 (35%), Gaps = 36/246 (14%)
Query: 45 PSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSD-SEMYVMPAEENADDSYEPPPVEQ 103
P+ P++ PA + S+ P + + ++ P E + S EP P
Sbjct: 702 PTTPKK------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 755
Query: 104 ETRPVHPALPFARGEYID---------NRSSQRHSPPFSKTLPSKPSWPSEKA------- 147
E P P +P + +++++R +T + P E A
Sbjct: 756 ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 815
Query: 148 --RLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPM 205
++T+T +T+ P L+ + P + I TE + P E A
Sbjct: 816 ESKITATTTQVTSTTTQDTTPFKITTLKTTT--LAPKVTTTKKTITTTEIMNKPEETAKP 873
Query: 206 VNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPL--KTTPVAS 263
+R+T ++TP T + + K P +PR K TTP K T
Sbjct: 874 KDRATNSKATTPKPQKPTKAPK-------KPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 926
Query: 264 QQNASS 269
+ N +S
Sbjct: 927 ELNPTS 932
Score = 33.5 bits (75), Expect = 0.41
Identities = 56/261 (21%), Positives = 85/261 (32%), Gaps = 56/261 (21%)
Query: 140 PSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIH-------P 192
P+ P E A T PA T +KP P P+ ++ P + IH P
Sbjct: 686 PTTPKETAPTTPKEPAPTTPKKP-APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 744
Query: 193 TESSSPPPE------KAPMVNRSTKPNSSTP-----------------------ASPPGT 223
S+ P P+ K P V + P ++ P A+P T
Sbjct: 745 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804
Query: 224 ASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVC------------ 271
+ T+S A + + + TTP K T + + A V
Sbjct: 805 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 864
Query: 272 ---EEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTE-GGNPT---VDGP 324
EE P +R S Q P P + +KP +PR + PT +
Sbjct: 865 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTST 924
Query: 325 LPSFSSNSTISEQEAGVLCKP 345
+P + S I+E +P
Sbjct: 925 MPELNPTSRIAEAMLQTTTRP 945
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 53.9 bits (128), Expect = 3e-07
Identities = 55/242 (22%), Positives = 88/242 (36%), Gaps = 31/242 (12%)
Query: 123 RSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQ--VPPKPKGLLEDEAD--Y 178
++S + P SK L P+ KA T+ PALT ++P P +P E
Sbjct: 222 KTSAKDLAPTSKVLAK----PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 277
Query: 179 VVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPP 238
+ + T S+P K P + +P +TP P T + + TKS P
Sbjct: 278 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT-KEPAPTTTKSAP 336
Query: 239 PAAPSPLPRAGKKP----------TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQ 288
P P KKP TTP + TP ++ A + E P + ++ ++
Sbjct: 337 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 396
Query: 289 EAVQSPVFPPAQKQIHQKPI------------PLPRFTEGGNPTVDGPLPSFSSNSTISE 336
A +P P P P P T+ T P P+ + ++ +
Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456
Query: 337 QE 338
+E
Sbjct: 457 KE 458
Score = 52.8 bits (125), Expect = 7e-07
Identities = 52/199 (26%), Positives = 73/199 (36%), Gaps = 18/199 (9%)
Query: 97 EPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPAL 156
EP P ++ P P P ++ + P + P+ P+ P E A T PA
Sbjct: 443 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPAP 501
Query: 157 TALQKPQ--VPPKPKGLLEDEADYVVP--VEDNDENYIHPTESSSPPPEKAPMVNRSTKP 212
T +KP P +P E P + + PT P P P T P
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTP 560
Query: 213 NSSTPASP--PGTASGRNSGAWETKSPPPAAPS-PLPRAGKKP--TTPLKTTPVASQQNA 267
TP +P P + + + K P P P P P K+P TTP +T P + A
Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620
Query: 268 SSVCEE-------KPIPAE 279
+ +E KP P E
Sbjct: 621 PTTLKEPAPTTPKKPAPKE 639
Score = 48.5 bits (114), Expect = 1e-05
Identities = 49/186 (26%), Positives = 63/186 (33%), Gaps = 29/186 (15%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPS--WPS 144
P E EP P +E P P P + T P KP+ P
Sbjct: 363 PKEPTPTTPKEPAPTTKEPAPTTPKEP-------------------APTAPKKPAPTTPK 403
Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
E A T PA T ++P P PK E + T S+P K P
Sbjct: 404 EPAPTTPKEPAPTTTKEPS-PTTPK---EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459
Query: 205 MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPS-PLPRAGKK--PTTPLKTTPV 261
+ +P +TP P T + K P P P P P KK PTTP + P
Sbjct: 460 SPTTTKEPAPTTPKEPAPTTP-KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518
Query: 262 ASQQNA 267
++ A
Sbjct: 519 TPKETA 524
Score = 48.1 bits (113), Expect = 2e-05
Identities = 56/234 (23%), Positives = 87/234 (37%), Gaps = 21/234 (8%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P E + EP P ++ P P P + + +P +K P+ P E
Sbjct: 262 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE--PAPTTPKEP 319
Query: 147 ARLTSTLPALTALQK-PQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPM 205
A T+ PA T + P P +P + P E PT ++ P E AP
Sbjct: 320 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPT 377
Query: 206 VNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAP-SPLPRAGKK--PTTP------- 255
+P +TP P TA + K P P P P P K+ PTTP
Sbjct: 378 TK---EPAPTTPKEPAPTAP-KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 433
Query: 256 LKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 309
K+ P +++ A + + P + ++ ++ A +P P +KP P
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP--KKPAP 485
Score = 46.6 bits (109), Expect = 5e-05
Identities = 50/211 (23%), Positives = 77/211 (36%), Gaps = 9/211 (4%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P E + EP P ++ P P P ++ + P + P+ P+ P E
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEP 374
Query: 147 ARLTSTLPALTALQKPQ--VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
A T PA T ++P P KP E P E P S + P E AP
Sbjct: 375 APTTKE-PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP--SPTTPKEPAP 431
Query: 205 MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQ 264
+S + PA P T + E P+P PTTP K P +
Sbjct: 432 TTTKSAPTTTKEPA--PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 489
Query: 265 QNASSVCEE-KPIPAERHRGSSHRQEAVQSP 294
+ A + +E P ++ ++ ++ A +P
Sbjct: 490 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 520
Score = 45.1 bits (105), Expect = 1e-04
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 11/151 (7%)
Query: 135 TLPSKPSWPSEKARLTSTL--PALTALQKPQ----VPPKPKGLLEDEADYVVPVEDNDEN 188
T P +P+ + K +TL PA T +KP P KG +D P +
Sbjct: 675 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 734
Query: 189 YIHPTESSSPPPEK-APMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPR 247
P E + P+K AP + P +S ++P T +S P + P P+
Sbjct: 735 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 794
Query: 248 A----GKKPTTPLKTTPVASQQNASSVCEEK 274
A K+P P TP A++ ++ ++K
Sbjct: 795 ALENSPKEPGVPTTKTPAATKPEMTTTAKDK 825
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/240 (24%), Positives = 82/240 (34%), Gaps = 27/240 (11%)
Query: 99 PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTA 158
P +E P P P ++ + + P + P+ P+ P E A T PA T
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTT 607
Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPA 218
K P PKG P T P E AP +TK +ST
Sbjct: 608 -PKETAPTTPKGTAPTTLKEPAPT----------TPKKPAPKELAPT---TTKEPTSTTC 653
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPA 278
P + + + K P P P PTTP T P ++ A + +KP P
Sbjct: 654 DKPAPTTPKGTAPTTPKEPAPTTPKE-----PAPTTPKGTAPTTLKEPAPTT-PKKPAPK 707
Query: 279 E----RHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTV-DGPLPSFSSNST 333
E +G + +P P K P P + PT + P P+ S ST
Sbjct: 708 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-PAPTTPKKPAPTTPETPPPTTSEVST 766
Score = 40.0 bits (92), Expect = 0.004
Identities = 47/188 (25%), Positives = 69/188 (36%), Gaps = 23/188 (12%)
Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDE-----NY 189
T P KP+ P E A T+ P T KP P PKG P +
Sbjct: 630 TTPKKPA-PKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 687
Query: 190 IHPTESSSPPP----EKAP--MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPS 243
PT P P + AP + +TK +ST + P + + + K P P P
Sbjct: 688 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 747
Query: 244 -PLPRAGKKP--TTPLKTTPVASQQNAS-------SVCEEKPIPAERHRGSSHRQEAVQS 293
P P + P TT +TP +++ + S E P + +S ++ V +
Sbjct: 748 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 807
Query: 294 PVFPPAQK 301
P A K
Sbjct: 808 TKTPAATK 815
Score = 37.0 bits (84), Expect = 0.037
Identities = 50/246 (20%), Positives = 87/246 (35%), Gaps = 36/246 (14%)
Query: 45 PSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSD-SEMYVMPAEENADDSYEPPPVEQ 103
P+ P++ PA + S+ P + + ++ P E + S EP P
Sbjct: 743 PTTPKK------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 796
Query: 104 ETRPVHPALPFARGEYID---------NRSSQRHSPPFSKTLPSKPSWPSEKA------- 147
E P P +P + +++++R +T + P E A
Sbjct: 797 ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 856
Query: 148 --RLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPM 205
++T+T +T+ P L+ + P + I TE + P E A
Sbjct: 857 ESKITATTTQVTSTTTQDTTPFKITTLKTTT--LAPKVTTTKKTITTTEIMNKPEETAKP 914
Query: 206 VNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPL--KTTPVAS 263
+R+T ++TP T + + K P +PR K TTP K T
Sbjct: 915 KDRATNSKATTPKPQKPTKAPK-------KPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 967
Query: 264 QQNASS 269
+ N +S
Sbjct: 968 ELNPTS 973
Score = 33.5 bits (75), Expect = 0.41
Identities = 56/261 (21%), Positives = 85/261 (32%), Gaps = 56/261 (21%)
Query: 140 PSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIH-------P 192
P+ P E A T PA T +KP P P+ ++ P + IH P
Sbjct: 727 PTTPKETAPTTPKEPAPTTPKKP-APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 785
Query: 193 TESSSPPPE------KAPMVNRSTKPNSSTP-----------------------ASPPGT 223
S+ P P+ K P V + P ++ P A+P T
Sbjct: 786 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845
Query: 224 ASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVC------------ 271
+ T+S A + + + TTP K T + + A V
Sbjct: 846 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 905
Query: 272 ---EEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTE-GGNPT---VDGP 324
EE P +R S Q P P + +KP +PR + PT +
Sbjct: 906 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTST 965
Query: 325 LPSFSSNSTISEQEAGVLCKP 345
+P + S I+E +P
Sbjct: 966 MPELNPTSRIAEAMLQTTTRP 986
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 53.9 bits (128), Expect = 3e-07
Identities = 55/242 (22%), Positives = 88/242 (36%), Gaps = 31/242 (12%)
Query: 123 RSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQ--VPPKPKGLLEDEAD--Y 178
++S + P SK L P+ KA T+ PALT ++P P +P E
Sbjct: 274 KTSAKDLAPTSKVLAK----PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 329
Query: 179 VVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPP 238
+ + T S+P K P + +P +TP P T + + TKS P
Sbjct: 330 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT-KEPAPTTTKSAP 388
Query: 239 PAAPSPLPRAGKKP----------TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQ 288
P P KKP TTP + TP ++ A + E P + ++ ++
Sbjct: 389 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 448
Query: 289 EAVQSPVFPPAQKQIHQKPI------------PLPRFTEGGNPTVDGPLPSFSSNSTISE 336
A +P P P P P T+ T P P+ + ++ +
Sbjct: 449 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508
Query: 337 QE 338
+E
Sbjct: 509 KE 510
Score = 52.8 bits (125), Expect = 7e-07
Identities = 52/199 (26%), Positives = 73/199 (36%), Gaps = 18/199 (9%)
Query: 97 EPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPAL 156
EP P ++ P P P ++ + P + P+ P+ P E A T PA
Sbjct: 495 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPAP 553
Query: 157 TALQKPQ--VPPKPKGLLEDEADYVVP--VEDNDENYIHPTESSSPPPEKAPMVNRSTKP 212
T +KP P +P E P + + PT P P P T P
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTP 612
Query: 213 NSSTPASP--PGTASGRNSGAWETKSPPPAAPS-PLPRAGKKP--TTPLKTTPVASQQNA 267
TP +P P + + + K P P P P P K+P TTP +T P + A
Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 672
Query: 268 SSVCEE-------KPIPAE 279
+ +E KP P E
Sbjct: 673 PTTLKEPAPTTPKKPAPKE 691
Score = 48.5 bits (114), Expect = 1e-05
Identities = 49/186 (26%), Positives = 63/186 (33%), Gaps = 29/186 (15%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPS--WPS 144
P E EP P +E P P P + T P KP+ P
Sbjct: 415 PKEPTPTTPKEPAPTTKEPAPTTPKEP-------------------APTAPKKPAPTTPK 455
Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
E A T PA T ++P P PK E + T S+P K P
Sbjct: 456 EPAPTTPKEPAPTTTKEPS-PTTPK---EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 205 MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPS-PLPRAGKK--PTTPLKTTPV 261
+ +P +TP P T + K P P P P P KK PTTP + P
Sbjct: 512 SPTTTKEPAPTTPKEPAPTTP-KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 570
Query: 262 ASQQNA 267
++ A
Sbjct: 571 TPKETA 576
Score = 48.1 bits (113), Expect = 2e-05
Identities = 56/234 (23%), Positives = 87/234 (37%), Gaps = 21/234 (8%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P E + EP P ++ P P P + + +P +K P+ P E
Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE--PAPTTPKEP 371
Query: 147 ARLTSTLPALTALQK-PQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPM 205
A T+ PA T + P P +P + P E PT ++ P E AP
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPT 429
Query: 206 VNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAP-SPLPRAGKK--PTTP------- 255
+P +TP P TA + K P P P P P K+ PTTP
Sbjct: 430 TK---EPAPTTPKEPAPTAP-KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 485
Query: 256 LKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 309
K+ P +++ A + + P + ++ ++ A +P P +KP P
Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP--KKPAP 537
Score = 46.6 bits (109), Expect = 5e-05
Identities = 50/211 (23%), Positives = 77/211 (36%), Gaps = 9/211 (4%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P E + EP P ++ P P P ++ + P + P+ P+ P E
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEP 426
Query: 147 ARLTSTLPALTALQKPQ--VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
A T PA T ++P P KP E P E P S + P E AP
Sbjct: 427 APTTKE-PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP--SPTTPKEPAP 483
Query: 205 MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQ 264
+S + PA P T + E P+P PTTP K P +
Sbjct: 484 TTTKSAPTTTKEPA--PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 541
Query: 265 QNASSVCEE-KPIPAERHRGSSHRQEAVQSP 294
+ A + +E P ++ ++ ++ A +P
Sbjct: 542 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 572
Score = 45.1 bits (105), Expect = 1e-04
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 11/151 (7%)
Query: 135 TLPSKPSWPSEKARLTSTL--PALTALQKPQ----VPPKPKGLLEDEADYVVPVEDNDEN 188
T P +P+ + K +TL PA T +KP P KG +D P +
Sbjct: 727 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 786
Query: 189 YIHPTESSSPPPEK-APMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPR 247
P E + P+K AP + P +S ++P T +S P + P P+
Sbjct: 787 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 846
Query: 248 A----GKKPTTPLKTTPVASQQNASSVCEEK 274
A K+P P TP A++ ++ ++K
Sbjct: 847 ALENSPKEPGVPTTKTPAATKPEMTTTAKDK 877
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/240 (24%), Positives = 82/240 (34%), Gaps = 27/240 (11%)
Query: 99 PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTA 158
P +E P P P ++ + + P + P+ P+ P E A T PA T
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTT 659
Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPA 218
K P PKG P T P E AP +TK +ST
Sbjct: 660 -PKETAPTTPKGTAPTTLKEPAPT----------TPKKPAPKELAPT---TTKEPTSTTC 705
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPA 278
P + + + K P P P PTTP T P ++ A + +KP P
Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKE-----PAPTTPKGTAPTTLKEPAPTT-PKKPAPK 759
Query: 279 E----RHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTV-DGPLPSFSSNST 333
E +G + +P P K P P + PT + P P+ S ST
Sbjct: 760 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-PAPTTPKKPAPTTPETPPPTTSEVST 818
Score = 40.0 bits (92), Expect = 0.004
Identities = 47/188 (25%), Positives = 69/188 (36%), Gaps = 23/188 (12%)
Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDE-----NY 189
T P KP+ P E A T+ P T KP P PKG P +
Sbjct: 682 TTPKKPA-PKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 739
Query: 190 IHPTESSSPPP----EKAP--MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPS 243
PT P P + AP + +TK +ST + P + + + K P P P
Sbjct: 740 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 799
Query: 244 -PLPRAGKKP--TTPLKTTPVASQQNAS-------SVCEEKPIPAERHRGSSHRQEAVQS 293
P P + P TT +TP +++ + S E P + +S ++ V +
Sbjct: 800 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 859
Query: 294 PVFPPAQK 301
P A K
Sbjct: 860 TKTPAATK 867
Score = 37.0 bits (84), Expect = 0.037
Identities = 50/246 (20%), Positives = 87/246 (35%), Gaps = 36/246 (14%)
Query: 45 PSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSD-SEMYVMPAEENADDSYEPPPVEQ 103
P+ P++ PA + S+ P + + ++ P E + S EP P
Sbjct: 795 PTTPKK------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 848
Query: 104 ETRPVHPALPFARGEYID---------NRSSQRHSPPFSKTLPSKPSWPSEKA------- 147
E P P +P + +++++R +T + P E A
Sbjct: 849 ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 908
Query: 148 --RLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPM 205
++T+T +T+ P L+ + P + I TE + P E A
Sbjct: 909 ESKITATTTQVTSTTTQDTTPFKITTLKTTT--LAPKVTTTKKTITTTEIMNKPEETAKP 966
Query: 206 VNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPL--KTTPVAS 263
+R+T ++TP T + + K P +PR K TTP K T
Sbjct: 967 KDRATNSKATTPKPQKPTKAPK-------KPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1019
Query: 264 QQNASS 269
+ N +S
Sbjct: 1020 ELNPTS 1025
Score = 33.5 bits (75), Expect = 0.41
Identities = 56/261 (21%), Positives = 85/261 (32%), Gaps = 56/261 (21%)
Query: 140 PSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIH-------P 192
P+ P E A T PA T +KP P P+ ++ P + IH P
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKP-APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 837
Query: 193 TESSSPPPE------KAPMVNRSTKPNSSTP-----------------------ASPPGT 223
S+ P P+ K P V + P ++ P A+P T
Sbjct: 838 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897
Query: 224 ASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVC------------ 271
+ T+S A + + + TTP K T + + A V
Sbjct: 898 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 957
Query: 272 ---EEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTE-GGNPT---VDGP 324
EE P +R S Q P P + +KP +PR + PT +
Sbjct: 958 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTST 1017
Query: 325 LPSFSSNSTISEQEAGVLCKP 345
+P + S I+E +P
Sbjct: 1018 MPELNPTSRIAEAMLQTTTRP 1038
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 53.9 bits (128), Expect = 3e-07
Identities = 55/242 (22%), Positives = 88/242 (36%), Gaps = 31/242 (12%)
Query: 123 RSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQ--VPPKPKGLLEDEAD--Y 178
++S + P SK L P+ KA T+ PALT ++P P +P E
Sbjct: 315 KTSAKDLAPTSKVLAK----PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 370
Query: 179 VVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPP 238
+ + T S+P K P + +P +TP P T + + TKS P
Sbjct: 371 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT-KEPAPTTTKSAP 429
Query: 239 PAAPSPLPRAGKKP----------TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQ 288
P P KKP TTP + TP ++ A + E P + ++ ++
Sbjct: 430 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 489
Query: 289 EAVQSPVFPPAQKQIHQKPI------------PLPRFTEGGNPTVDGPLPSFSSNSTISE 336
A +P P P P P T+ T P P+ + ++ +
Sbjct: 490 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549
Query: 337 QE 338
+E
Sbjct: 550 KE 551
Score = 52.8 bits (125), Expect = 7e-07
Identities = 52/199 (26%), Positives = 73/199 (36%), Gaps = 18/199 (9%)
Query: 97 EPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPAL 156
EP P ++ P P P ++ + P + P+ P+ P E A T PA
Sbjct: 536 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPAP 594
Query: 157 TALQKPQ--VPPKPKGLLEDEADYVVP--VEDNDENYIHPTESSSPPPEKAPMVNRSTKP 212
T +KP P +P E P + + PT P P P T P
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTP 653
Query: 213 NSSTPASP--PGTASGRNSGAWETKSPPPAAPS-PLPRAGKKP--TTPLKTTPVASQQNA 267
TP +P P + + + K P P P P P K+P TTP +T P + A
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713
Query: 268 SSVCEE-------KPIPAE 279
+ +E KP P E
Sbjct: 714 PTTLKEPAPTTPKKPAPKE 732
Score = 48.5 bits (114), Expect = 1e-05
Identities = 49/186 (26%), Positives = 63/186 (33%), Gaps = 29/186 (15%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPS--WPS 144
P E EP P +E P P P + T P KP+ P
Sbjct: 456 PKEPTPTTPKEPAPTTKEPAPTTPKEP-------------------APTAPKKPAPTTPK 496
Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
E A T PA T ++P P PK E + T S+P K P
Sbjct: 497 EPAPTTPKEPAPTTTKEPS-PTTPK---EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 205 MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPS-PLPRAGKK--PTTPLKTTPV 261
+ +P +TP P T + K P P P P P KK PTTP + P
Sbjct: 553 SPTTTKEPAPTTPKEPAPTTP-KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 611
Query: 262 ASQQNA 267
++ A
Sbjct: 612 TPKETA 617
Score = 48.1 bits (113), Expect = 2e-05
Identities = 56/234 (23%), Positives = 87/234 (37%), Gaps = 21/234 (8%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P E + EP P ++ P P P + + +P +K P+ P E
Sbjct: 355 PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE--PAPTTPKEP 412
Query: 147 ARLTSTLPALTALQK-PQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPM 205
A T+ PA T + P P +P + P E PT ++ P E AP
Sbjct: 413 APTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT--PKEPAPT 470
Query: 206 VNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAP-SPLPRAGKK--PTTP------- 255
+P +TP P TA + K P P P P P K+ PTTP
Sbjct: 471 TK---EPAPTTPKEPAPTAP-KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 526
Query: 256 LKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 309
K+ P +++ A + + P + ++ ++ A +P P +KP P
Sbjct: 527 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP--KKPAP 578
Score = 46.6 bits (109), Expect = 5e-05
Identities = 50/211 (23%), Positives = 77/211 (36%), Gaps = 9/211 (4%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P E + EP P ++ P P P ++ + P + P+ P+ P E
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEP 467
Query: 147 ARLTSTLPALTALQKPQ--VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP 204
A T PA T ++P P KP E P E P S + P E AP
Sbjct: 468 APTTKE-PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP--SPTTPKEPAP 524
Query: 205 MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQ 264
+S + PA P T + E P+P PTTP K P +
Sbjct: 525 TTTKSAPTTTKEPA--PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 582
Query: 265 QNASSVCEE-KPIPAERHRGSSHRQEAVQSP 294
+ A + +E P ++ ++ ++ A +P
Sbjct: 583 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP 613
Score = 45.1 bits (105), Expect = 1e-04
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 11/151 (7%)
Query: 135 TLPSKPSWPSEKARLTSTL--PALTALQKPQ----VPPKPKGLLEDEADYVVPVEDNDEN 188
T P +P+ + K +TL PA T +KP P KG +D P +
Sbjct: 768 TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA 827
Query: 189 YIHPTESSSPPPEK-APMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPR 247
P E + P+K AP + P +S ++P T +S P + P P+
Sbjct: 828 PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 887
Query: 248 A----GKKPTTPLKTTPVASQQNASSVCEEK 274
A K+P P TP A++ ++ ++K
Sbjct: 888 ALENSPKEPGVPTTKTPAATKPEMTTTAKDK 918
Score = 44.3 bits (103), Expect = 2e-04
Identities = 59/240 (24%), Positives = 82/240 (34%), Gaps = 27/240 (11%)
Query: 99 PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTA 158
P +E P P P ++ + + P + P+ P+ P E A T PA T
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA-PTTPKEPAPTTPKEPAPTT 700
Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPA 218
K P PKG P T P E AP +TK +ST
Sbjct: 701 -PKETAPTTPKGTAPTTLKEPAPT----------TPKKPAPKELAPT---TTKEPTSTTC 746
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPA 278
P + + + K P P P PTTP T P ++ A + +KP P
Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKE-----PAPTTPKGTAPTTLKEPAPTT-PKKPAPK 800
Query: 279 E----RHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTV-DGPLPSFSSNST 333
E +G + +P P K P P + PT + P P+ S ST
Sbjct: 801 ELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-PAPTTPKKPAPTTPETPPPTTSEVST 859
Score = 40.0 bits (92), Expect = 0.004
Identities = 47/188 (25%), Positives = 69/188 (36%), Gaps = 23/188 (12%)
Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDE-----NY 189
T P KP+ P E A T+ P T KP P PKG P +
Sbjct: 723 TTPKKPA-PKELAPTTTKEPTSTTCDKP-APTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 780
Query: 190 IHPTESSSPPP----EKAP--MVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPS 243
PT P P + AP + +TK +ST + P + + + K P P P
Sbjct: 781 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 840
Query: 244 -PLPRAGKKP--TTPLKTTPVASQQNAS-------SVCEEKPIPAERHRGSSHRQEAVQS 293
P P + P TT +TP +++ + S E P + +S ++ V +
Sbjct: 841 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 900
Query: 294 PVFPPAQK 301
P A K
Sbjct: 901 TKTPAATK 908
Score = 37.0 bits (84), Expect = 0.037
Identities = 50/246 (20%), Positives = 87/246 (35%), Gaps = 36/246 (14%)
Query: 45 PSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSD-SEMYVMPAEENADDSYEPPPVEQ 103
P+ P++ PA + S+ P + + ++ P E + S EP P
Sbjct: 836 PTTPKK------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKAL 889
Query: 104 ETRPVHPALPFARGEYID---------NRSSQRHSPPFSKTLPSKPSWPSEKA------- 147
E P P +P + +++++R +T + P E A
Sbjct: 890 ENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTT 949
Query: 148 --RLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPM 205
++T+T +T+ P L+ + P + I TE + P E A
Sbjct: 950 ESKITATTTQVTSTTTQDTTPFKITTLKTTT--LAPKVTTTKKTITTTEIMNKPEETAKP 1007
Query: 206 VNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPL--KTTPVAS 263
+R+T ++TP T + + K P +PR K TTP K T
Sbjct: 1008 KDRATNSKATTPKPQKPTKAPK-------KPTSTKKPKTMPRVRKPKTTPTPRKMTSTMP 1060
Query: 264 QQNASS 269
+ N +S
Sbjct: 1061 ELNPTS 1066
Score = 33.5 bits (75), Expect = 0.41
Identities = 56/261 (21%), Positives = 85/261 (32%), Gaps = 56/261 (21%)
Query: 140 PSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIH-------P 192
P+ P E A T PA T +KP P P+ ++ P + IH P
Sbjct: 820 PTTPKETAPTTPKEPAPTTPKKP-APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 878
Query: 193 TESSSPPPE------KAPMVNRSTKPNSSTP-----------------------ASPPGT 223
S+ P P+ K P V + P ++ P A+P T
Sbjct: 879 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 938
Query: 224 ASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVC------------ 271
+ T+S A + + + TTP K T + + A V
Sbjct: 939 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 998
Query: 272 ---EEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTE-GGNPT---VDGP 324
EE P +R S Q P P + +KP +PR + PT +
Sbjct: 999 NKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTST 1058
Query: 325 LPSFSSNSTISEQEAGVLCKP 345
+P + S I+E +P
Sbjct: 1059 MPELNPTSRIAEAMLQTTTRP 1079
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 52.8 bits (125), Expect = 7e-07
Identities = 51/185 (27%), Positives = 72/185 (38%), Gaps = 19/185 (10%)
Query: 130 PPFSKTLPSKPSWPSEK--------ARLTSTLPALT---ALQKPQVPPKPKGLLEDEADY 178
P LP +PS PS + AR + PALT L +P + P+ LLEDE
Sbjct: 860 PALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPP 919
Query: 179 VVPVEDND-ENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSP 237
P+ + Y+ + PP P V ++P P PP S + + P
Sbjct: 920 APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQP--PPPLPPPPHPSVQQQLQQQPPPP 977
Query: 238 PPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFP 297
PP P P P+ +P PV Q S ++P P + + H Q P
Sbjct: 978 PPPQPQPPPQQQHQP----PPRPVHLQPMQFSTHIQQPPPPQGQQ-PPHPPPGQQPPPPQ 1032
Query: 298 PAQKQ 302
PA+ Q
Sbjct: 1033 PAKPQ 1037
Score = 43.9 bits (102), Expect = 3e-04
Identities = 69/319 (21%), Positives = 114/319 (35%), Gaps = 68/319 (21%)
Query: 37 KKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDE----------------HSD 80
+K+ V A S + +SES + E SD DS+ E + H
Sbjct: 684 EKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHH 743
Query: 81 SEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKP 140
+M PA +PPP Q+ P P + Q+ PP P P
Sbjct: 744 QQMQQAPAPV----PQQPPPPPQQPPPPPPP-----------QQQQQPPPP-----PPPP 783
Query: 141 SWPSEKA-RLTSTLPALTALQKPQVPPKPKGLLEDEADYVV-----------------PV 182
S P + A + S+ P A Q P + P+ G + D + P
Sbjct: 784 SMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPP 843
Query: 183 EDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSP----- 237
E + +++ SPP + + ++P++ A PP A T++P
Sbjct: 844 EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQP 903
Query: 238 PPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFP 297
P A P + ++P P P+ S Q + + + + S + ++ P P
Sbjct: 904 PMAQPPQVLLEDEEPPAP----PLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP 959
Query: 298 P-----AQKQIHQKPIPLP 311
P Q+Q+ Q+P P P
Sbjct: 960 PPPHPSVQQQLQQQPPPPP 978
Score = 34.7 bits (78), Expect = 0.18
Identities = 48/218 (22%), Positives = 68/218 (31%), Gaps = 47/218 (21%)
Query: 97 EPPPV--EQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLP 154
+PP V E E P P + + Q + K P P PS K +
Sbjct: 907 QPPQVLLEDEEPPAPP---------LTSMQMQLYLQQLQKVQPPTPLLPSVKVQ------ 951
Query: 155 ALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNS 214
+ P +PP P ++ + P + P + PPP V+ S
Sbjct: 952 ---SQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP---VHLQPMQFS 1005
Query: 215 STPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEK 274
+ PP PP P P G++P P P Q+ S K
Sbjct: 1006 THIQQPP---------------PPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHK 1050
Query: 275 PIPAERHRGSSHRQEA-----VQSPVFPPAQKQIHQKP 307
P + H +EA + SP Q HQ P
Sbjct: 1051 SDP----YSTGHLREAPSPLMIHSPQMSQFQSLTHQSP 1084
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 52.0 bits (123), Expect = 1e-06
Identities = 59/247 (23%), Positives = 90/247 (36%), Gaps = 50/247 (20%)
Query: 98 PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKAR--------- 148
PPPV RP+ + P RG ++ SP P+ P +P +
Sbjct: 184 PPPVPSTPRPIQSS-PHNRGSPPVPGGPRQPSPG-----PTPPPFPGNRGTALGGGSIRQ 237
Query: 149 --LTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMV 206
L+S+ P +P +PP P L+D+ P N + PP P V
Sbjct: 238 SPLSSSSPFSN---RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPV 294
Query: 207 NRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQN 266
+ +P++S+ A PP PPP+ P P P ++ TP Q+N
Sbjct: 295 PSTPRPSASSQAPPP--------------PPPPSRPGPPPL--PPSSSGNDETPRLPQRN 338
Query: 267 ASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLP 326
S P+P+ G P+ PP ++P P R G + + P P
Sbjct: 339 LSLSSSTPPLPSPGRSG----------PLPPPPS----ERPPPPVRDPPGRSGPLPPPPP 384
Query: 327 SFSSNST 333
+ ST
Sbjct: 385 VSRNGST 391
Score = 36.6 bits (83), Expect = 0.049
Identities = 50/184 (27%), Positives = 66/184 (35%), Gaps = 42/184 (22%)
Query: 95 SYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLP 154
S PPP +RP P L PP S P P L+S+ P
Sbjct: 304 SQAPPPPPPPSRPGPPPL-----------------PPSSSGNDETPRLPQRNLSLSSSTP 346
Query: 155 ALTAL-QKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPN 213
L + + +PP P PV D P S P P P V+R+ +
Sbjct: 347 PLPSPGRSGPLPPPPSERPPP------PVRD-------PPGRSGPLPPPPP-VSRNGSTS 392
Query: 214 SSTPASPP-GTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNA--SSV 270
+ PA+P + SG +S P P P P AG P P P S +N S
Sbjct: 393 RALPATPQLPSRSGVDS---PRSGPRPPLPPDRPSAGAPPPPP----PSTSIRNGFQDSP 445
Query: 271 CEEK 274
CE++
Sbjct: 446 CEDE 449
Score = 30.4 bits (67), Expect = 3.5
Identities = 43/149 (28%), Positives = 53/149 (35%), Gaps = 37/149 (24%)
Query: 194 ESSSPPPEKAPMVNRSTKPNSSTPASPPG----TASGRNSGAWETKSPPPAAPSPLPRAG 249
+S P P RST +P S PG + G SG E + P P P G
Sbjct: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQR--NRMPPPRPDVG 177
Query: 250 KKPTT---PLKTTPVASQQNASSVCEEKPIPAERH-RGSSHRQEAVQSPVFPPAQKQIHQ 305
KP + P+ +TP +PI + H RG SP P +Q
Sbjct: 178 SKPDSIPPPVPSTP-------------RPIQSSPHNRG---------SPPVPGGPRQPSP 215
Query: 306 KPIPLP----RFTE-GGNPTVDGPLPSFS 329
P P P R T GG PL S S
Sbjct: 216 GPTPPPFPGNRGTALGGGSIRQSPLSSSS 244
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 52.0 bits (123), Expect = 1e-06
Identities = 59/247 (23%), Positives = 90/247 (36%), Gaps = 50/247 (20%)
Query: 98 PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKAR--------- 148
PPPV RP+ + P RG ++ SP P+ P +P +
Sbjct: 184 PPPVPSTPRPIQSS-PHNRGSPPVPGGPRQPSPG-----PTPPPFPGNRGTALGGGSIRQ 237
Query: 149 --LTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMV 206
L+S+ P +P +PP P L+D+ P N + PP P V
Sbjct: 238 SPLSSSSPFSN---RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPV 294
Query: 207 NRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQN 266
+ +P++S+ A PP PPP+ P P P ++ TP Q+N
Sbjct: 295 PSTPRPSASSQAPPP--------------PPPPSRPGPPPL--PPSSSGNDETPRLPQRN 338
Query: 267 ASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLP 326
S P+P+ G P+ PP ++P P R G + + P P
Sbjct: 339 LSLSSSTPPLPSPGRSG----------PLPPPPS----ERPPPPVRDPPGRSGPLPPPPP 384
Query: 327 SFSSNST 333
+ ST
Sbjct: 385 VSRNGST 391
Score = 36.6 bits (83), Expect = 0.049
Identities = 50/184 (27%), Positives = 66/184 (35%), Gaps = 42/184 (22%)
Query: 95 SYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLP 154
S PPP +RP P L PP S P P L+S+ P
Sbjct: 304 SQAPPPPPPPSRPGPPPL-----------------PPSSSGNDETPRLPQRNLSLSSSTP 346
Query: 155 ALTAL-QKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPN 213
L + + +PP P PV D P S P P P V+R+ +
Sbjct: 347 PLPSPGRSGPLPPPPSERPPP------PVRD-------PPGRSGPLPPPPP-VSRNGSTS 392
Query: 214 SSTPASPP-GTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNA--SSV 270
+ PA+P + SG +S P P P P AG P P P S +N S
Sbjct: 393 RALPATPQLPSRSGVDS---PRSGPRPPLPPDRPSAGAPPPPP----PSTSIRNGFQDSP 445
Query: 271 CEEK 274
CE++
Sbjct: 446 CEDE 449
Score = 30.4 bits (67), Expect = 3.5
Identities = 43/149 (28%), Positives = 53/149 (35%), Gaps = 37/149 (24%)
Query: 194 ESSSPPPEKAPMVNRSTKPNSSTPASPPG----TASGRNSGAWETKSPPPAAPSPLPRAG 249
+S P P RST +P S PG + G SG E + P P P G
Sbjct: 120 DSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQR--NRMPPPRPDVG 177
Query: 250 KKPTT---PLKTTPVASQQNASSVCEEKPIPAERH-RGSSHRQEAVQSPVFPPAQKQIHQ 305
KP + P+ +TP +PI + H RG SP P +Q
Sbjct: 178 SKPDSIPPPVPSTP-------------RPIQSSPHNRG---------SPPVPGGPRQPSP 215
Query: 306 KPIPLP----RFTE-GGNPTVDGPLPSFS 329
P P P R T GG PL S S
Sbjct: 216 GPTPPPFPGNRGTALGGGSIRQSPLSSSS 244
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 52.0 bits (123), Expect = 1e-06
Identities = 99/454 (21%), Positives = 161/454 (35%), Gaps = 74/454 (16%)
Query: 10 PASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFD 69
P S Q +K+ ++I EGG + A P + + + E W
Sbjct: 709 PGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGP-------LASAESLEPVSWR---- 757
Query: 70 SDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHS 129
E P HS A +A P + P+H + P + + S R
Sbjct: 758 ---EGPSGHSTLPRSPRDAPCSASSELSGP-----STPLHTSSP------VQGKESTRRQ 803
Query: 130 PPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENY 189
S T S P+++ LP ++ + P P G + P+ + +
Sbjct: 804 DTRSPT-----SAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE------PLAPSPVSP 852
Query: 190 IHPTESSSP-PPEKAPMVNRSTKPNSSTPASP-PGTASGRNSGAWETKSPPPAAP----- 242
P S S P E++P + ++P SP P T G W+ PP +P
Sbjct: 853 TFPPSSPSDWPQERSP----GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPL 908
Query: 243 SPLPR------AGKKP--TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSP 294
+P+P A +P ++P P+A+ + + + + P+P +RH +Q P
Sbjct: 909 TPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGL-SQPPLPEKRHLPGPGQQPGPWGP 967
Query: 295 --VFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACD 352
PA+ H P ++ T + P SN + + K WY
Sbjct: 968 EQASSPARGISHHVTFA-PLLSDNVPQTPEPPTQESQSNVKFVQDTS----KFWYKPHLS 1022
Query: 353 RKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVV---------FFNKRVYNIPVRFIEA 403
R A AL + G+FLIR S L V + V + F+
Sbjct: 1023 RDQAI-ALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIE 1081
Query: 404 TKQYALGRKK-NGEEYFGSVAEIIRNHQHSPLVL 436
T + K E YFGS++ ++ H SP+ L
Sbjct: 1082 TGPKGVKIKGCPSEPYFGSLSALVSQHSISPISL 1115
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 52.0 bits (123), Expect = 1e-06
Identities = 99/454 (21%), Positives = 161/454 (35%), Gaps = 74/454 (16%)
Query: 10 PASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFD 69
P S Q +K+ ++I EGG + A P + + + E W
Sbjct: 833 PGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGP-------LASAESLEPVSWR---- 881
Query: 70 SDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHS 129
E P HS A +A P + P+H + P + + S R
Sbjct: 882 ---EGPSGHSTLPRSPRDAPCSASSELSGP-----STPLHTSSP------VQGKESTRRQ 927
Query: 130 PPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENY 189
S T S P+++ LP ++ + P P G + P+ + +
Sbjct: 928 DTRSPT-----SAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE------PLAPSPVSP 976
Query: 190 IHPTESSSP-PPEKAPMVNRSTKPNSSTPASP-PGTASGRNSGAWETKSPPPAAP----- 242
P S S P E++P + ++P SP P T G W+ PP +P
Sbjct: 977 TFPPSSPSDWPQERSP----GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPL 1032
Query: 243 SPLPR------AGKKP--TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSP 294
+P+P A +P ++P P+A+ + + + + P+P +RH +Q P
Sbjct: 1033 TPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGL-SQPPLPEKRHLPGPGQQPGPWGP 1091
Query: 295 --VFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACD 352
PA+ H P ++ T + P SN + + K WY
Sbjct: 1092 EQASSPARGISHHVTFA-PLLSDNVPQTPEPPTQESQSNVKFVQDTS----KFWYKPHLS 1146
Query: 353 RKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVV---------FFNKRVYNIPVRFIEA 403
R A AL + G+FLIR S L V + V + F+
Sbjct: 1147 RDQAI-ALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIE 1205
Query: 404 TKQYALGRKK-NGEEYFGSVAEIIRNHQHSPLVL 436
T + K E YFGS++ ++ H SP+ L
Sbjct: 1206 TGPKGVKIKGCPSEPYFGSLSALVSQHSISPISL 1239
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 52.0 bits (123), Expect = 1e-06
Identities = 99/454 (21%), Positives = 161/454 (35%), Gaps = 74/454 (16%)
Query: 10 PASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFD 69
P S Q +K+ ++I EGG + A P + + + E W
Sbjct: 843 PGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGP-------LASAESLEPVSWR---- 891
Query: 70 SDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHS 129
E P HS A +A P + P+H + P + + S R
Sbjct: 892 ---EGPSGHSTLPRSPRDAPCSASSELSGP-----STPLHTSSP------VQGKESTRRQ 937
Query: 130 PPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENY 189
S T S P+++ LP ++ + P P G + P+ + +
Sbjct: 938 DTRSPT-----SAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPE------PLAPSPVSP 986
Query: 190 IHPTESSSP-PPEKAPMVNRSTKPNSSTPASP-PGTASGRNSGAWETKSPPPAAP----- 242
P S S P E++P + ++P SP P T G W+ PP +P
Sbjct: 987 TFPPSSPSDWPQERSP----GGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPL 1042
Query: 243 SPLPR------AGKKP--TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSP 294
+P+P A +P ++P P+A+ + + + + P+P +RH +Q P
Sbjct: 1043 TPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGL-SQPPLPEKRHLPGPGQQPGPWGP 1101
Query: 295 --VFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACD 352
PA+ H P ++ T + P SN + + K WY
Sbjct: 1102 EQASSPARGISHHVTFA-PLLSDNVPQTPEPPTQESQSNVKFVQDTS----KFWYKPHLS 1156
Query: 353 RKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVV---------FFNKRVYNIPVRFIEA 403
R A AL + G+FLIR S L V + V + F+
Sbjct: 1157 RDQAI-ALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIE 1215
Query: 404 TKQYALGRKK-NGEEYFGSVAEIIRNHQHSPLVL 436
T + K E YFGS++ ++ H SP+ L
Sbjct: 1216 TGPKGVKIKGCPSEPYFGSLSALVSQHSISPISL 1249
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 50.4 bits (119), Expect = 3e-06
Identities = 63/281 (22%), Positives = 98/281 (34%), Gaps = 38/281 (13%)
Query: 59 DEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGE 118
+EE++ ++ D + E +E + +E +MPA E + PPP+ P LP
Sbjct: 365 EEEKKEEEEKDKEGEEKEERAVAEE-MMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTS 423
Query: 119 YIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTS---TLPALTALQKPQVPPKPKGLLEDE 175
P LPS P P+++ + S +PA + ++ + P P E E
Sbjct: 424 PPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAERE 483
Query: 176 ADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRST------------------------- 210
A P + T + PP + + +ST
Sbjct: 484 AARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTP 543
Query: 211 -KPNSSTPASPPGTASGRNSGAWETKSPP-PAAPSPLPRAGKKPTTPLKTTPVASQQNAS 268
+ P PP T SPP P P+P+P + PT P +TPV +
Sbjct: 544 RRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP--STPVPLPEKRR 601
Query: 269 SVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 309
S+ E R +S +E P PP P P
Sbjct: 602 SILREPTF-----RWTSLTRELPPPPPAPPPPPAPSPPPAP 637
Score = 36.2 bits (82), Expect = 0.063
Identities = 35/131 (26%), Positives = 40/131 (30%), Gaps = 26/131 (19%)
Query: 194 ESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPT 253
E+ PPP P P+ P PP T SPPP P P P
Sbjct: 398 EAKLPPPPLTPPA-----PSPPPPLPPPST------------SPPPPLCPPPPPPVSPPP 440
Query: 254 TPLKTTPVASQQNASSVCEEKPIPAERHRG-----SSHRQEAVQSPVFPPAQKQIHQKPI 308
P P A ++ S P R RG S R E + P P
Sbjct: 441 LPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGT----SPPT 496
Query: 309 PLPRFTEGGNP 319
P P GG P
Sbjct: 497 PTPSTATGGPP 507
Score = 35.8 bits (81), Expect = 0.083
Identities = 46/175 (26%), Positives = 60/175 (34%), Gaps = 41/175 (23%)
Query: 98 PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALT 157
PPPV+Q P LP P S T P+ SW L LP +
Sbjct: 2212 PPPVKQ------PPLP----------------PTISPTAPT--SWTLPPGPLLGVLPVVG 2247
Query: 158 ALQK-PQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPP---PEKAPMVNRSTKPN 213
++ P PP P L+ P + + SPP P KAP ++ + +
Sbjct: 2248 VVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEAS 2307
Query: 214 SSTPASPPGTASGRNS----------GAWETKSP--PPAAPSPLPRAGKKPTTPL 256
TP PG SG S G + P P SP P + P PL
Sbjct: 2308 EDTP-QVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPL 2361
Score = 30.4 bits (67), Expect = 3.5
Identities = 52/218 (23%), Positives = 72/218 (33%), Gaps = 47/218 (21%)
Query: 110 PALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPK 169
PA P A G S P S+ L + P+ P+ P + L P PK
Sbjct: 2138 PAPPLANG-----------SQP-SQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPK 2185
Query: 170 GLLEDEADYVVPVEDNDENYIHPTESSSP--PPEKAPMVNRSTKPNSSTPAS-PPGTASG 226
++ V + ++ P PP K P + + P + T + PPG G
Sbjct: 2186 ----PATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLG 2241
Query: 227 RNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSH 286
+ PP P PL T L + P + + A I +R S
Sbjct: 2242 VLPVVGVVRPAPPPPPPPL-------TLVLSSGPASPPRQA--------IRVKRVSTFSG 2286
Query: 287 RQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGP 324
R SP PP P PR E G + D P
Sbjct: 2287 R-----SPPAPP--------PYKAPRLDEDGEASEDTP 2311
Score = 30.0 bits (66), Expect = 4.5
Identities = 39/159 (24%), Positives = 58/159 (36%), Gaps = 32/159 (20%)
Query: 134 KTLPSKPSWPSEK-ARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENY--- 189
+ L +P P E+ A L + T + P +P G + D V V E +
Sbjct: 1779 RILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPI 1838
Query: 190 ------IHPTESSSPPPE---------KAPMVNRSTKPNSSTPASP---PGTASGRNS-- 229
+ P S+PPP K P + S +P P PG+ S
Sbjct: 1839 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI 1898
Query: 230 ---GAWETKSPPPAAPSPLPRAGKKPTT-----PLKTTP 260
G + +PP + P P A + P + PLKT+P
Sbjct: 1899 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSP 1937
Score = 29.6 bits (65), Expect = 5.9
Identities = 39/192 (20%), Positives = 66/192 (34%), Gaps = 33/192 (17%)
Query: 73 ENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPF 132
E+ D SD E + ++D+ P + R P RG ++++ P
Sbjct: 112 ESSDGESDEEEF---QGFHSDEDVAPSSLRSALRSQRGRAPRGRGR--KHKTTPLPPPRL 166
Query: 133 SKTLPSKPSWPSEKARLTST---LPALTAL-QKPQVPPKPKGLLEDEADYVVPVEDNDEN 188
+ P+ P P+ K T + ALT L ++ Q P P+ + +
Sbjct: 167 ADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPST----------- 215
Query: 189 YIHPTESSSPPP----------EKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPP 238
P S PP ++A +V + PP +G+W+ K P
Sbjct: 216 ---PRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGP 272
Query: 239 PAAPSPLPRAGK 250
P R G+
Sbjct: 273 GPGPGTPRRGGQ 284
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 49.7 bits (117), Expect = 6e-06
Identities = 40/142 (28%), Positives = 56/142 (39%), Gaps = 18/142 (12%)
Query: 199 PPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAW-ETKSPPPAAPSPLPRAGKKPTTPLK 257
P AP + P +S A P R G E SPP P+P PR + TTP
Sbjct: 257 PSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAP 316
Query: 258 TTP----------VASQQNASSVCEEK--PIPAERHRGSSHRQEAVQSPVFPP-----AQ 300
TP + Q +SS+ + +P + RG+ E +P P Q
Sbjct: 317 PTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQ 376
Query: 301 KQIHQKPIPLPRFTEGGNPTVD 322
+ +KP PLP + G P+ D
Sbjct: 377 AEPKKKPAPLPPSSSPGPPSQD 398
Score = 39.7 bits (91), Expect = 0.006
Identities = 72/310 (23%), Positives = 109/310 (35%), Gaps = 49/310 (15%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
PA AD P E RP P P G+ + SPP + P+ P SE
Sbjct: 262 PAGAEADG----PKASPEARPQIPTKPRVPGKL-----QELASPPAGRPTPA-PRKASE- 310
Query: 147 ARLTSTLPALTALQKPQVPPKPKGLLEDEAD--------YVVPVEDNDENYIHPTESSSP 198
ST PA +P+ + + L+E + +PV P+E +
Sbjct: 311 ----STTPA-PPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVP-KPRGTPKPSEGTPA 364
Query: 199 PPEKAPMVNR-----STKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPT 253
P + P + KP P+S PG S + + A PSP KP
Sbjct: 365 PRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPY 424
Query: 254 TPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP---- 309
P + ++ A + PA H S+ + + P + + ++P P
Sbjct: 425 NPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPS 484
Query: 310 -------LPRFTEGGNPTVDGPLPSFSSNSTISE---QEAGV-LCKPWYAGACDRKSAEE 358
R + P+ P P+ S S SE Q AG L +P A + S+E
Sbjct: 485 ASPLALHASRLSHSEPPSAT-PSPALSVESLSSESASQTAGAELLEP---PAVPKSSSEP 540
Query: 359 ALHRSNKDGS 368
A+H G+
Sbjct: 541 AVHAPGTPGN 550
Score = 32.7 bits (73), Expect = 0.70
Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 13/116 (11%)
Query: 221 PGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS---------QQNASSVC 271
PG ++ A P A+P P+ KP P K +AS + AS
Sbjct: 253 PGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASEST 312
Query: 272 EEKPIPAERHRGSSHRQEAV-QSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLP 326
P P R R S ++ V Q+ ++H+ P+P PR T P+ P P
Sbjct: 313 TPAP-PTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTP--KPSEGTPAP 365
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 48.9 bits (115), Expect = 9e-06
Identities = 55/182 (30%), Positives = 67/182 (36%), Gaps = 22/182 (12%)
Query: 154 PALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAP---MVNRST 210
PA T P P P L A + P + SPP AP M R+
Sbjct: 507 PATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTK 566
Query: 211 KPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTP--LKTTPVASQQNAS 268
+P + P PP SG ++S PPA PLP P TP L V S A
Sbjct: 567 RPAPARPTMPPPQVSG-------SRSSPPA--PPLPPGSGSPGTPQALPRRLVGSSLRAP 617
Query: 269 SVCEE-KPIPAERHRGSSHRQEAVQSPVFP-PAQKQIHQKPIPL--PRFTEGGNPTVDGP 324
+V P P + R S R A SP P PA P+ L P + G T +G
Sbjct: 618 TVPPPLPPTPPQPARRQSRRSPASPSPASPGPAS----PSPVSLSNPAQVDLGAATAEGG 673
Query: 325 LP 326
P
Sbjct: 674 AP 675
Score = 31.6 bits (70), Expect = 1.6
Identities = 49/198 (24%), Positives = 70/198 (35%), Gaps = 19/198 (9%)
Query: 142 WPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDN-------DENYIHPTE 194
WP EK + L A ++ QV + L++ AD + P + N + T
Sbjct: 433 WPPEKEGDQAQLDA-ASVSSIQVVGVVEALIQS-ADTLFPGDINFNVSGLFSAVTLQDTV 490
Query: 195 SSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTT 254
S E+ P T + PA P A + TK + P P + K +
Sbjct: 491 SDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRS 550
Query: 255 PLKT-TPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP--LP 311
P +T PV + ++P PA + SP PP P LP
Sbjct: 551 PPETAAPVEDMARRT----KRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALP 606
Query: 312 RFTEGGN---PTVDGPLP 326
R G + PTV PLP
Sbjct: 607 RRLVGSSLRAPTVPPPLP 624
Score = 29.6 bits (65), Expect = 5.9
Identities = 32/127 (25%), Positives = 44/127 (34%), Gaps = 25/127 (19%)
Query: 129 SPPFSKTLPSKPSWPSEKARLTST-LPALTALQKPQV---------PPKPKGLLEDEADY 178
SP +++ P + + AR T PA + PQV PP P G
Sbjct: 544 SPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQ 603
Query: 179 VVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPP 238
+P + PT PP TP P S R+ + SP
Sbjct: 604 ALPRRLVGSSLRAPTVPPPLPP---------------TPPQPARRQSRRSPASPSPASPG 648
Query: 239 PAAPSPL 245
PA+PSP+
Sbjct: 649 PASPSPV 655
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 48.5 bits (114), Expect = 1e-05
Identities = 69/321 (21%), Positives = 117/321 (36%), Gaps = 45/321 (14%)
Query: 7 ITVPASQKLRQLQ---KMVHDIKNNEGGIMNKI-KKLKVKAPPSV--------------- 47
+ VPA KL +L+ + V +NE + +I K++ PP +
Sbjct: 327 LKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFP 386
Query: 48 -PRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYV-MPAEENADDSYEPPPVEQET 105
P +D S + ++ D + N + + S + + ++ D E P + +
Sbjct: 387 FPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPS 446
Query: 106 RPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVP 165
P+ P + E + S+ S T S S SE +S L+ P
Sbjct: 447 SSAPPSAPQSLPEPV--ASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPE 504
Query: 166 PKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTAS 225
P+P + + D N++ + PPE RST+P P S + S
Sbjct: 505 PEPPTTNKWQLD----------NWLTKVSQPAAPPEGP----RSTEPPRRHPESKGSSDS 550
Query: 226 GRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS--------QQNASSVCEEKPIP 277
+ E+K PPP + S PRA + P K + S +Q + +KP+
Sbjct: 551 ATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVK 610
Query: 278 AERHRGSSHRQEAVQSPVFPP 298
A GS + + P P
Sbjct: 611 ASARAGSRTSLQGEREPGLLP 631
Score = 42.4 bits (98), Expect = 9e-04
Identities = 64/289 (22%), Positives = 99/289 (34%), Gaps = 53/289 (18%)
Query: 40 KVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPP 99
KV P + P ++E P E SD EHS+S+ +PP
Sbjct: 521 KVSQPAAPPEGPRSTEPPRRHPESKGS---SDSATSQEHSESK--------------DPP 563
Query: 100 PVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTAL 159
P P P G+ +S + PP +T+ +K P + + ++ + T+L
Sbjct: 564 PKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ--PKKPVKASARAGSRTSL 621
Query: 160 QKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPAS 219
Q + P GLL P D+ S P K R+ N PA
Sbjct: 622 QGEREP----GLL--------PYGSRDQT------SKDKPKVKTKGRPRAAASNEPKPAV 663
Query: 220 PPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTP--LKTTPVASQQNASSVCEEKPIP 277
PP + ++ + S + P P + + TP P+ Q
Sbjct: 664 PPSSEKKKHKSSLPAPSKALSGPEP-AKDNVEDRTPEHFALVPLTESQGPP--------- 713
Query: 278 AERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLP 326
H GS R + V + + P+PL R T+ +P D P P
Sbjct: 714 ---HSGSGSRTSGCRQAVVVQEDSRKDRLPLPL-RDTKLLSPLRDTPPP 758
Score = 34.3 bits (77), Expect = 0.24
Identities = 36/136 (26%), Positives = 48/136 (35%), Gaps = 24/136 (17%)
Query: 124 SSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVE 183
SS H SKT PS+PS S K + P ++ QKP P + E
Sbjct: 840 SSSSHKES-SKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRRE---------- 888
Query: 184 DNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASG-RNSGAWETKSPPPAAP 242
++ P K+ +S +SS P G R+S + S A P
Sbjct: 889 ---------ADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANP 939
Query: 243 SP---LPRAGKKPTTP 255
P LP KP P
Sbjct: 940 FPVPSLPNGNSKPGKP 955
Score = 32.7 bits (73), Expect = 0.70
Identities = 40/183 (21%), Positives = 63/183 (34%), Gaps = 8/183 (4%)
Query: 162 PQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPP 221
PQ P+P + D+D + +ESSS E+ + + P P
Sbjct: 454 PQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLE------TPAPEPEP 507
Query: 222 GTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERH 281
T + W TK PAAP PR+ + P ++ + + E K P +
Sbjct: 508 PTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSS 567
Query: 282 RGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRF--TEGGNPTVDGPLPSFSSNSTISEQEA 339
+ P QK Q+ P + T+ V + S S E+E
Sbjct: 568 SKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREP 627
Query: 340 GVL 342
G+L
Sbjct: 628 GLL 630
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/243 (24%), Positives = 90/243 (37%), Gaps = 44/243 (18%)
Query: 98 PPPVEQETRPVHPALPFARGEYIDNRSSQRHSP------------PFSKTLPSKPSWPSE 145
P + +P+ PA P A+ + SS++ P P + P+KP P++
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP--PTQ 413
Query: 146 KARLTSTLPALTALQKPQVPPKP-KGLLEDEADYVVPVED-----NDENYIHPTESSS-- 197
+ L LQ P P P K ++ +P + PT+ S
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473
Query: 198 PPPEKAPMVNRSTKPNSSTPASP----PGTASGRNSGAWETKSPPPAAPSPLPRAGKKPT 253
P P K P P PA P PG+A + TK PPP P P A P
Sbjct: 474 PGPAKPP-------PQQPGPAKPPPQQPGSAKPPSQQPGSTK-PPPQQPGP---AKPSPQ 522
Query: 254 TPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQ-------EAVQSPVFPPAQKQIHQK 306
P T P + Q ++ ++P PA+ S + + +Q P P+ KQ +
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
Query: 307 PIP 309
+P
Sbjct: 583 GLP 585
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/235 (24%), Positives = 88/235 (37%), Gaps = 34/235 (14%)
Query: 100 PVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTAL 159
P Q+T P A P + + + PP K P+ PS KA+ P +L
Sbjct: 677 PQPQQTSPKKDAAP---KQDLSKAPEPKKPPPLVKQ-PTLHGSPSAKAKQP---PEADSL 729
Query: 160 QKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTK-PNSSTPA 218
KP P +P E + PV D+ P++ MV +T +SS+
Sbjct: 730 SKPAPPKEPSVPSEQDK---APVADDK-------------PKQPKMVKPTTDLVSSSSAT 773
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEK---- 274
+ P S + E K+ PP + P T K +P S+ + K
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833
Query: 275 PIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKP--IPLPRFTEGGNPTVDGPLPS 327
P P+ +G + AQ ++ KP P+P+ G+PT GP P+
Sbjct: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK----GSPTPPGPRPT 884
Score = 42.7 bits (99), Expect = 7e-04
Identities = 55/234 (23%), Positives = 80/234 (34%), Gaps = 24/234 (10%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P + D + P +RP RGE + PP + P KP P+++
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP--PAQQ 318
Query: 147 ARLTSTLPALTALQKPQVPP-KPKGLLEDEADYVVPVEDNDENYIHPTESSSPP-----P 200
+ P P PP +P GL + A V+ + P ++ PP P
Sbjct: 319 PGHEKSQPG------PAKPPAQPSGLTKPLAQQPGTVKPP----VQPPGTTKPPAQPLGP 368
Query: 201 EKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTP---LK 257
K P ++ SS P A G + P PA P KP L+
Sbjct: 369 AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 258 TTPVASQQNASSVCEEKP--IPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 309
+ A + V + P IPA++ G P PP+Q KP P
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQ-AGPGKTSAQQTGPTKPPSQLPGPAKPPP 481
Score = 39.7 bits (91), Expect = 0.006
Identities = 67/301 (22%), Positives = 100/301 (33%), Gaps = 45/301 (14%)
Query: 42 KAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPV 101
K PP + ++ SP+ + +Q P E P E + + PV
Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQ-----------PPEADSLSKPAPPKEPSVPSEQDKAPV 749
Query: 102 EQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK----ARLTSTLPALT 157
+ +P P + + + + S+ +KP PS K A +T P T
Sbjct: 750 ADD-KPKQPKMVKPTTDLVSSSSAT-----------TKPDIPSSKVQSQAEEKTTPPLKT 797
Query: 158 ALQKPQVPPKPKGLLEDEADY-VVPVEDNDENYI-HPTESSSPPPEKA--PMVNRSTKPN 213
KP P G D +P +D I HP SS +K P+ +
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Query: 214 SSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQ-----NAS 268
+ T SP A G+ P P P P AG+ TP ++ Q N
Sbjct: 858 AQTKMSPKPDAKPMPKGS-------PTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG 910
Query: 269 SVCE-EKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEG-GNPTVDGPLP 326
S+ + K P + + + +F A I P P G G P P P
Sbjct: 911 SITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP 970
Query: 327 S 327
S
Sbjct: 971 S 971
Score = 36.6 bits (83), Expect = 0.049
Identities = 59/272 (21%), Positives = 98/272 (36%), Gaps = 36/272 (13%)
Query: 45 PSVPRRDYASESPADEEEQWSDDFDSDYENPDEHS----------DSEMYVMPAEENADD 94
P +P +S+ + EE+ + +D P + DS+ PA ++
Sbjct: 776 PDIP----SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831
Query: 95 SYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPS-KPSWPSEKARLTSTL 153
S+ P E++ P + E ++ P +K +P P+ P + T+
Sbjct: 832 SHPGP--SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTV 889
Query: 154 PALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPN 213
P PQ PKP+ + + + D ++ PT K S
Sbjct: 890 PT------PQQSPKPQEQSRRFSLNLGSITDAPKS--QPTTPQETVTGKLFGFGASIFSQ 941
Query: 214 SS---TPASPPGTASGRNSGAWETKSP----PPAAPSPLPRAGKKPTTPLKTTPVASQQN 266
+S + A PG S GA ++P PP + P G+ P P K+ PV +
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK 1001
Query: 267 ASSVCEEKPIPAERHRGSSHRQEAVQSPVFPP 298
A + EK P + R E + P PP
Sbjct: 1002 APAA--EKLEPKAEQAPTVKRTETEKKP--PP 1029
Score = 35.0 bits (79), Expect = 0.14
Identities = 45/176 (25%), Positives = 63/176 (35%), Gaps = 29/176 (16%)
Query: 98 PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALT 157
PPPV + + L F H P PSKP P + LP T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT------------HRPE-----PSKP--PIAPKPVIPQLPTTT 2523
Query: 158 ALQKP-QVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKA-PMVNRSTKPN-- 213
QKP + PKP GL + + V D PT SP K+ P ++S
Sbjct: 2524 --QKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYV 2581
Query: 214 ----SSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQ 265
S P +P +++ + +W SP S P P P++S+Q
Sbjct: 2582 VITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQ 2637
Score = 31.2 bits (69), Expect = 2.0
Identities = 59/267 (22%), Positives = 90/267 (33%), Gaps = 43/267 (16%)
Query: 73 ENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALP----FARGEYIDN-RSSQR 127
E+P H E+ DS PP +Q RP P P ++ D RS Q+
Sbjct: 77 ESPSMHRKQEL----------DSSHPP--KQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124
Query: 128 ---HSPPFSKTLPSKPSWPSEKARLTSTLP-------ALTALQKPQVPPKPKGLLED--- 174
SP SK ++ +S +P AL+A+ P L+ D
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184
Query: 175 ------EADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRN 228
+ VV E I PP+ P + +P +S +
Sbjct: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQP 244
Query: 229 SGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGS--SH 286
+ KS PP P+ + P T P+ + + + E + S S
Sbjct: 245 E---KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301
Query: 287 RQEAVQSPV--FPPAQKQIHQKPIPLP 311
+ +Q P PPAQ+ H+K P P
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGP 328
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/243 (24%), Positives = 90/243 (37%), Gaps = 44/243 (18%)
Query: 98 PPPVEQETRPVHPALPFARGEYIDNRSSQRHSP------------PFSKTLPSKPSWPSE 145
P + +P+ PA P A+ + SS++ P P + P+KP P++
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP--PTQ 413
Query: 146 KARLTSTLPALTALQKPQVPPKP-KGLLEDEADYVVPVED-----NDENYIHPTESSS-- 197
+ L LQ P P P K ++ +P + PT+ S
Sbjct: 414 QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473
Query: 198 PPPEKAPMVNRSTKPNSSTPASP----PGTASGRNSGAWETKSPPPAAPSPLPRAGKKPT 253
P P K P P PA P PG+A + TK PPP P P A P
Sbjct: 474 PGPAKPP-------PQQPGPAKPPPQQPGSAKPPSQQPGSTK-PPPQQPGP---AKPSPQ 522
Query: 254 TPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQ-------EAVQSPVFPPAQKQIHQK 306
P T P + Q ++ ++P PA+ S + + +Q P P+ KQ +
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
Query: 307 PIP 309
+P
Sbjct: 583 GLP 585
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/235 (24%), Positives = 88/235 (37%), Gaps = 34/235 (14%)
Query: 100 PVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTAL 159
P Q+T P A P + + + PP K P+ PS KA+ P +L
Sbjct: 677 PQPQQTSPKKDAAP---KQDLSKAPEPKKPPPLVKQ-PTLHGSPSAKAKQP---PEADSL 729
Query: 160 QKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTK-PNSSTPA 218
KP P +P E + PV D+ P++ MV +T +SS+
Sbjct: 730 SKPAPPKEPSVPSEQDK---APVADDK-------------PKQPKMVKPTTDLVSSSSAT 773
Query: 219 SPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEK---- 274
+ P S + E K+ PP + P T K +P S+ + K
Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISH 833
Query: 275 PIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKP--IPLPRFTEGGNPTVDGPLPS 327
P P+ +G + AQ ++ KP P+P+ G+PT GP P+
Sbjct: 834 PGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK----GSPTPPGPRPT 884
Score = 42.7 bits (99), Expect = 7e-04
Identities = 55/234 (23%), Positives = 80/234 (34%), Gaps = 24/234 (10%)
Query: 87 PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
P + D + P +RP RGE + PP + P KP P+++
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKP--PAQQ 318
Query: 147 ARLTSTLPALTALQKPQVPP-KPKGLLEDEADYVVPVEDNDENYIHPTESSSPP-----P 200
+ P P PP +P GL + A V+ + P ++ PP P
Sbjct: 319 PGHEKSQPG------PAKPPAQPSGLTKPLAQQPGTVKPP----VQPPGTTKPPAQPLGP 368
Query: 201 EKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTP---LK 257
K P ++ SS P A G + P PA P KP L+
Sbjct: 369 AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 258 TTPVASQQNASSVCEEKP--IPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 309
+ A + V + P IPA++ G P PP+Q KP P
Sbjct: 429 SPAKAPGPTKTPVQQPGPGKIPAQQ-AGPGKTSAQQTGPTKPPSQLPGPAKPPP 481
Score = 39.7 bits (91), Expect = 0.006
Identities = 67/301 (22%), Positives = 100/301 (33%), Gaps = 45/301 (14%)
Query: 42 KAPPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPV 101
K PP + ++ SP+ + +Q P E P E + + PV
Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQ-----------PPEADSLSKPAPPKEPSVPSEQDKAPV 749
Query: 102 EQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK----ARLTSTLPALT 157
+ +P P + + + + S+ +KP PS K A +T P T
Sbjct: 750 ADD-KPKQPKMVKPTTDLVSSSSAT-----------TKPDIPSSKVQSQAEEKTTPPLKT 797
Query: 158 ALQKPQVPPKPKGLLEDEADY-VVPVEDNDENYI-HPTESSSPPPEKA--PMVNRSTKPN 213
KP P G D +P +D I HP SS +K P+ +
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Query: 214 SSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQ-----NAS 268
+ T SP A G+ P P P P AG+ TP ++ Q N
Sbjct: 858 AQTKMSPKPDAKPMPKGS-------PTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG 910
Query: 269 SVCE-EKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEG-GNPTVDGPLP 326
S+ + K P + + + +F A I P P G G P P P
Sbjct: 911 SITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAP 970
Query: 327 S 327
S
Sbjct: 971 S 971
Score = 36.6 bits (83), Expect = 0.049
Identities = 59/272 (21%), Positives = 98/272 (36%), Gaps = 36/272 (13%)
Query: 45 PSVPRRDYASESPADEEEQWSDDFDSDYENPDEHS----------DSEMYVMPAEENADD 94
P +P +S+ + EE+ + +D P + DS+ PA ++
Sbjct: 776 PDIP----SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831
Query: 95 SYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPS-KPSWPSEKARLTSTL 153
S+ P E++ P + E ++ P +K +P P+ P + T+
Sbjct: 832 SHPGP--SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTV 889
Query: 154 PALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPN 213
P PQ PKP+ + + + D ++ PT K S
Sbjct: 890 PT------PQQSPKPQEQSRRFSLNLGSITDAPKS--QPTTPQETVTGKLFGFGASIFSQ 941
Query: 214 SS---TPASPPGTASGRNSGAWETKSP----PPAAPSPLPRAGKKPTTPLKTTPVASQQN 266
+S + A PG S GA ++P PP + P G+ P P K+ PV +
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK 1001
Query: 267 ASSVCEEKPIPAERHRGSSHRQEAVQSPVFPP 298
A + EK P + R E + P PP
Sbjct: 1002 APAA--EKLEPKAEQAPTVKRTETEKKP--PP 1029
Score = 35.0 bits (79), Expect = 0.14
Identities = 45/176 (25%), Positives = 63/176 (35%), Gaps = 29/176 (16%)
Query: 98 PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALT 157
PPPV + + L F H P PSKP P + LP T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT------------HRPE-----PSKP--PIAPKPVIPQLPTTT 2523
Query: 158 ALQKP-QVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKA-PMVNRSTKPN-- 213
QKP + PKP GL + + V D PT SP K+ P ++S
Sbjct: 2524 --QKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYV 2581
Query: 214 ----SSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQ 265
S P +P +++ + +W SP S P P P++S+Q
Sbjct: 2582 VITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQ 2637
Score = 31.2 bits (69), Expect = 2.0
Identities = 59/267 (22%), Positives = 90/267 (33%), Gaps = 43/267 (16%)
Query: 73 ENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALP----FARGEYIDN-RSSQR 127
E+P H E+ DS PP +Q RP P P ++ D RS Q+
Sbjct: 77 ESPSMHRKQEL----------DSSHPP--KQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124
Query: 128 ---HSPPFSKTLPSKPSWPSEKARLTSTLP-------ALTALQKPQVPPKPKGLLED--- 174
SP SK ++ +S +P AL+A+ P L+ D
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184
Query: 175 ------EADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRN 228
+ VV E I PP+ P + +P +S +
Sbjct: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQP 244
Query: 229 SGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGS--SH 286
+ KS PP P+ + P T P+ + + + E + S S
Sbjct: 245 E---KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301
Query: 287 RQEAVQSPV--FPPAQKQIHQKPIPLP 311
+ +Q P PPAQ+ H+K P P
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGP 328
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 48.1 bits (113), Expect = 2e-05
Identities = 72/314 (22%), Positives = 112/314 (35%), Gaps = 71/314 (22%)
Query: 50 RDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVH 109
+++ P +E +Q+ + + +YE +EH E Y+ E+ PV +E P
Sbjct: 9754 KEFEEYEPTEEYDQYEEYEEREYERYEEH---EEYITEPEK----PIPVKPVPEEPVPTK 9806
Query: 110 PALPFAR-------GEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKP 162
P P A+ E + ++ PP K EK R++ T + +P
Sbjct: 9807 PKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEP 9866
Query: 163 --QVPPKPKGLLEDEADYV-------------VPVE---------------------DND 186
+VP KPK ++ +E V VP E + +
Sbjct: 9867 AAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEE 9926
Query: 187 ENYIHP-----TESSSPP--PEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWET-KSPP 238
E YIH TE P P K P V R P P P + E K P
Sbjct: 9927 EEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPE 9986
Query: 239 PAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEK-PIPAERHRGSSHRQEAVQSPVFP 297
P +P+ K P + P V EEK P+P + + EA + V
Sbjct: 9987 EKVPVLIPKKEKPPPAKVPEVP------KKPVPEEKVPVPVPK------KVEAPPAKVPE 10034
Query: 298 PAQKQIHQKPIPLP 311
+K + +K +P+P
Sbjct: 10035 VPKKPVPEKKVPVP 10048
Score = 48.1 bits (113), Expect = 2e-05
Identities = 69/318 (21%), Positives = 115/318 (36%), Gaps = 38/318 (11%)
Query: 6 KITVPASQKLRQLQKMVHDIKNN---EGGIMNKIKKLKVKAPPSVPRRDYASESPADEEE 62
K+ VPA +K+ V ++ E + K PP VP++ P +
Sbjct: 10044 KVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQ 10103
Query: 63 QWSDDFDSDYENPDEHSDSEMYVMPAEENA-DDSYEPPPVEQETRPVHPALPFARGEYID 121
+ F+ + +E E V+P EE + E P E+E P +P EY+
Sbjct: 10104 EEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVP-PEEEYVP 10162
Query: 122 NRSS----QRHSPPFSKTLPSKPSWPSEKARLTS---TLPALTALQKPQVPPKPKGLLED 174
+ P +P P K ++T +P +VP PK + +
Sbjct: 10163 EEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKV--E 10220
Query: 175 EADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWET 234
E ++P E+ + P E + P E+ P+ P PP
Sbjct: 10221 EKRIILPKEEE----VLPVEVTEEPEEE-PI------SEEEIPEEPPSIEEVEEVA---- 10265
Query: 235 KSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSP 294
PP P + +A P TPV + A K IP E+ ++EA +
Sbjct: 10266 ---PPRVPEVIKKA-----VPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAK 10317
Query: 295 VFPPAQKQIHQKPIPLPR 312
V P K++ +K + +P+
Sbjct: 10318 V-PEVPKKVPEKKVLVPK 10334
Score = 44.7 bits (104), Expect = 2e-04
Identities = 75/321 (23%), Positives = 113/321 (35%), Gaps = 62/321 (19%)
Query: 48 PRRDYAS---ESPADEEEQWSDDFDSD---YENPDEHSDSEM----------YVMPAEEN 91
P DY E+ + E+W +DF+ YE + + + E + +E
Sbjct: 9097 PDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEV 9156
Query: 92 ADDSYE------------PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTL-PS 138
++S+E PPP + +PV + + + P SK + P
Sbjct: 9157 YEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQ 9216
Query: 139 KPS-WPSEKARLTSTLPALTALQKPQVPPKPKGLL----EDEADYVVPVEDND---ENYI 190
KPS P ++ + +PA+ K V + K E+E VP + E I
Sbjct: 9217 KPSRTPVQEEVIEVKVPAVHT--KKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKI 9274
Query: 191 HPTESSS-PPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWET-KSPPPAAPSPLPRA 248
H S PP K P + P P P E K P P P+P
Sbjct: 9275 HVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVP 9334
Query: 249 GKKPTTPLKTTPVASQQNASSVCEEK-PIP-AERHRGSSHRQEAVQSPVF---------- 296
K+P P K V + V EEK P+P A++ + VQ V
Sbjct: 9335 KKEPAAPPKVPEVPKK----PVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQ 9390
Query: 297 -----PPAQKQIHQKPIPLPR 312
PPA +I +K +P R
Sbjct: 9391 REESPPPAVPEIPKKKVPEER 9411
Score = 42.4 bits (98), Expect = 9e-04
Identities = 53/241 (21%), Positives = 83/241 (34%), Gaps = 43/241 (17%)
Query: 75 PDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSK 134
P+ + E + EE E VE+E +H F E + P
Sbjct: 9897 PEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEV--------VPVIPV 9948
Query: 135 TLPSKPSWPSEKARLTSTLPA---LTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIH 191
+P P P + + +P + P+VP KP E++ ++P ++
Sbjct: 9949 KVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKP----EEKVPVLIPKKEK------ 9998
Query: 192 PTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWET-KSPPPAAPSPLPRAGK 250
PPP K P V + P P P + E K P P P+P K
Sbjct: 9999 ------PPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKK 10052
Query: 251 KPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPL 310
P K V + E+KP P + + EA PP + ++P+P+
Sbjct: 10053 VEAPPAKVPEVPKKLIPE---EKKPTPVPK------KVEA------PPPKVPKKREPVPV 10097
Query: 311 P 311
P
Sbjct: 10098 P 10098
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/148 (27%), Positives = 55/148 (37%), Gaps = 16/148 (10%)
Query: 134 KTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKP----KGLLEDEADYVVPVEDNDENY 189
K LP + P E+ L S L ++P+V PK K E PVE+ +
Sbjct: 10934 KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT 10993
Query: 190 IHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAG 249
+ E P P K P + KP PA P + +T PPP P P P A
Sbjct: 10994 VTKRERKIPEPTKVPEI----KPAIPLPAPEP---KPKPEAEVKTIKPPPVEPEPTPIA- 11045
Query: 250 KKPTTPLKTTPVASQQNASSVCEEKPIP 277
P+ V + A + EE P
Sbjct: 11046 ----APVTVPVVGKKAEAKAPKEEAAKP 11069
Score = 37.4 bits (85), Expect = 0.028
Identities = 64/300 (21%), Positives = 103/300 (34%), Gaps = 42/300 (14%)
Query: 46 SVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPP--PVEQ 103
+VP + P E + F+ E E +E+ P PP PV +
Sbjct: 10644 AVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPE 10703
Query: 104 ETRPV----HPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPS------------EKA 147
+ P P LP + + P +P KP P EK
Sbjct: 10704 KKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPL--VVPKKPEAPPAKVPEVPKEVVPEKK 10761
Query: 148 RLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDEN----------YIHPTESSS 197
P + + P+VP KP +LE++ VPV + E+ I P E +
Sbjct: 10762 VAVPKKPEVPPAKVPEVPKKP--VLEEKP--AVPVPERAESPPPEVYEEPEEIAPEEEIA 10817
Query: 198 PPPEKAPMVNRSTKPNSSTPASPPG----TASGRNSGAWETKSPPPAAPSP---LPRAGK 250
P EK V +P PA P + + ++PPP P P + +
Sbjct: 10818 PEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKL 10877
Query: 251 KPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQ-SPVFPPAQKQIHQKPIP 309
KP P + + + K IP ++ E V+ +P+ P ++ +K +P
Sbjct: 10878 KPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLP 10937
Score = 36.6 bits (83), Expect = 0.049
Identities = 59/261 (22%), Positives = 86/261 (32%), Gaps = 26/261 (9%)
Query: 76 DEHSDSEMYVMPAEENADDSY---EPPPVEQETR--PVHPALPFARGEYIDNRSSQRHSP 130
+E + E Y E + + + E VE+E R VH + E ++ + +P
Sbjct: 10381 EEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPK-AP 10439
Query: 131 PFSKTLPSK---PSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDE 187
P + K P P K PA +VP PK ++ +E V +E
Sbjct: 10440 PKGPEISEKIIPPKKPPTKVVPRKEPPA-------KVPEVPKKIVVEEK-----VRVPEE 10487
Query: 188 NYIHPTESSS--PPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPL 245
+ PT+ PP E P P A PP E K P P P
Sbjct: 10488 PRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPE 10547
Query: 246 PRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQ 305
K P P P A E P P E + P PP + ++
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPESP-PPEVPEAPKEVVPEKKVPAAPPKKPEV-- 10604
Query: 306 KPIPLPRFTEGGNPTVDGPLP 326
P+ +P + P P+P
Sbjct: 10605 TPVKVPEAPKEVVPEKKVPVP 10625
Score = 36.2 bits (82), Expect = 0.063
Identities = 45/178 (25%), Positives = 63/178 (35%), Gaps = 27/178 (15%)
Query: 124 SSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYV-VPV 182
S + PP LP KP+ P E A + +P P+VP PK + +E V VP
Sbjct: 9279 SKRVEPPPKVPELPEKPA-PEEVAPVP--IPKKVEPPAPKVPEVPKKPVPEEKKPVPVPK 9335
Query: 183 EDNDENYIHPTESSSPPPEK---APMVNRSTKPNSSTPASPPGTASGRNSG--AWETKSP 237
++ P P PE+ P+ + P + P G + +SP
Sbjct: 9336 KEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESP 9395
Query: 238 PPAAPS-----------PLPRAG-------KKPTTPLKTTPVASQQNASSVCEEKPIP 277
PPA P P+PR K P P K P V ++ P P
Sbjct: 9396 PPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPP 9453
Score = 35.0 bits (79), Expect = 0.14
Identities = 31/113 (27%), Positives = 41/113 (36%), Gaps = 27/113 (23%)
Query: 192 PTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKK 251
P + PPP K P + P PA P + K PPP +P KK
Sbjct: 9569 PAKIEEPPPAKVPEAPKKIVPEKKVPAPVPK----------KEKVPPP----KVPEEPKK 9614
Query: 252 PTTPLKTTPVASQQNASSVCEEKPIPA---ERHRGSSHRQE---AVQSPVFPP 298
P K P + E+P+PA ERH + ++ AV PP
Sbjct: 9615 PVPEKKVPPKVIKM-------EEPLPAKVTERHMQITQEEKVLVAVTKKEAPP 9660
Score = 33.1 bits (74), Expect = 0.54
Identities = 65/290 (22%), Positives = 90/290 (31%), Gaps = 52/290 (17%)
Query: 37 KKLKVKAPPS--VPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADD 94
K + K PP+ VPR++ ++ P ++ ++ E P V+P +E +
Sbjct: 10448 KIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPE 10507
Query: 95 SYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLP 154
P P ++ P +P A E + + PP P KP P K
Sbjct: 10508 KKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVP--VPP-----PKKPEVPPTK-------- 10552
Query: 155 ALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNS 214
VP PK VP + E ES P +AP + P
Sbjct: 10553 ---------VPEVPKA--------AVPEKKVPEAIPPKPESPPPEVPEAP---KEVVPEK 10592
Query: 215 STPASPP--------GTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQN 266
PA+PP E K P P P K P P P
Sbjct: 10593 KVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPE 10652
Query: 267 ASSVCEEKPIP-----AERHRGSSHRQEAVQ--SPVFPPAQKQIHQKPIP 309
A E P P E E V+ P PP +KP+P
Sbjct: 10653 AIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVP 10702
Score = 29.3 bits (64), Expect = 7.7
Identities = 22/93 (23%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 211 KPNSSTPASPPGTASGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSV 270
KP S +P +PP A+ ++ SP +PSP+ +P+++ A++ + S +
Sbjct: 260 KPKSRSP-TPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARISTSPI 318
Query: 271 -CEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQ 302
P+ + + S+ P PP KQ
Sbjct: 319 RSVRSPLLMRKTQAST----VATGPEVPPPWKQ 347
Score = 29.3 bits (64), Expect = 7.7
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 289 EAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYA 348
++V++P P++ ++ +P PLP+F P D P S ++E GV
Sbjct: 857 KSVKAPTVKPSETRVRAEPTPLPQF-----PFADTPDTYKSEAGVEVKKEVGVS----IT 907
Query: 349 GACDRKSAEEALH 361
G R+ E LH
Sbjct: 908 GTTVREERFEVLH 920
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,577,688
Number of Sequences: 37866
Number of extensions: 1407755
Number of successful extensions: 12851
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 178
Number of HSP's successfully gapped in prelim test: 1180
Number of HSP's that attempted gapping in prelim test: 8353
Number of HSP's gapped (non-prelim): 3872
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.