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Search of human proteins with 7019503
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019503 prolactin regulatory element binding protein [Homo
sapiens]
(417 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019503 prolactin regulatory element binding protein [Homo sa... 844 0.0
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 47 4e-05
gi|222080092 WD repeat domain 91 [Homo sapiens] 46 7e-05
gi|32189425 WD repeat domain 69 [Homo sapiens] 46 7e-05
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 45 9e-05
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H... 45 9e-05
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 45 9e-05
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho... 45 9e-05
gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1... 45 1e-04
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 45 2e-04
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 43 6e-04
gi|16445438 bromodomain and WD repeat domain containing 1 isofor... 42 8e-04
gi|16445436 bromodomain and WD repeat domain containing 1 isofor... 42 8e-04
gi|55769546 PAK1 interacting protein 1 [Homo sapiens] 42 0.001
gi|55743075 angio-associated, migratory cell protein [Homo sapiens] 42 0.001
gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 40 0.003
gi|189571685 WD repeat, sterile alpha motif and U-box domain con... 40 0.003
gi|189571683 WD repeat, sterile alpha motif and U-box domain con... 40 0.003
gi|189571681 WD repeat, sterile alpha motif and U-box domain con... 40 0.003
gi|209969680 Fzr1 protein isoform 1 [Homo sapiens] 40 0.004
gi|209969678 Fzr1 protein isoform 3 [Homo sapiens] 40 0.004
gi|33620742 Fzr1 protein isoform 2 [Homo sapiens] 40 0.004
gi|21281677 WD repeat domain 36 [Homo sapiens] 40 0.005
gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo s... 40 0.005
gi|48928050 F-box and WD repeat domain containing 11 isoform C [... 39 0.007
gi|48928048 F-box and WD repeat domain containing 11 isoform A [... 39 0.007
gi|48928046 F-box and WD repeat domain containing 11 isoform B [... 39 0.007
gi|21071067 TBP-associated factor 5 [Homo sapiens] 39 0.009
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 39 0.009
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 39 0.009
>gi|7019503 prolactin regulatory element binding protein [Homo
sapiens]
Length = 417
Score = 844 bits (2181), Expect = 0.0
Identities = 417/417 (100%), Positives = 417/417 (100%)
Query: 1 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS 60
MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS
Sbjct: 1 MGRRRAPELYRAPFPLYALQVDPSTGLLIAAGGGGAAKTGIKNGVHFLQLELINGRLSAS 60
Query: 61 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG 120
LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG
Sbjct: 61 LLHSHDTETRATMNLALAGDILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQGPRQRKG 120
Query: 121 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV 180
AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV
Sbjct: 121 AAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRV 180
Query: 181 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF 240
WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF
Sbjct: 181 WKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTF 240
Query: 241 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH 300
SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH
Sbjct: 241 SSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGH 300
Query: 301 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE 360
EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE
Sbjct: 301 EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLPEKGRGPE 360
Query: 361 LLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL 417
LLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
Sbjct: 361 LLGSHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL 417
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 46.6 bits (109), Expect = 4e-05
Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLK 218
V F+ ++ LATG TD VR+W V F H G + LA P+GK L + G D +
Sbjct: 432 VKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQR 491
Query: 219 ASVW 222
+W
Sbjct: 492 LKLW 495
Score = 32.7 bits (73), Expect = 0.63
Identities = 17/64 (26%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPD-GKLVTVGRDLK 218
+ F+ + LA+ G D +++W + S E + H I L PD G + + D
Sbjct: 474 LAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNS 533
Query: 219 ASVW 222
VW
Sbjct: 534 VRVW 537
>gi|222080092 WD repeat domain 91 [Homo sapiens]
Length = 747
Score = 45.8 bits (107), Expect = 7e-05
Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 148 QTDFSSDPLQKVV---CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLAL 204
Q FS DP + FNH+ LL TG DG +R++ + E + ++AH GE+ +
Sbjct: 553 QLQFSLDPEPIAINCTAFNHNGNLLVTGAADGVIRLFDMQQHECAMSWRAHYGEVYSVEF 612
Query: 205 GPDGKLV-TVGRDLKASVW 222
D V ++G D K W
Sbjct: 613 SYDENTVYSIGEDGKFIQW 631
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 45.8 bits (107), Expect = 7e-05
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 161 CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKA 219
CF++ L+AT DG R++ + + + + + HEGEI ++ P G L+T D A
Sbjct: 310 CFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTA 369
Query: 220 SVW 222
+W
Sbjct: 370 RIW 372
Score = 43.5 bits (101), Expect = 4e-04
Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 3/71 (4%)
Query: 158 KVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVG 214
++VC FN +TL+ATG D ++W + + E+V + H EI L+ G +++T
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGS 238
Query: 215 RDLKASVWQKD 225
D VW D
Sbjct: 239 FDHTVVVWDAD 249
Score = 33.1 bits (74), Expect = 0.48
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG-RDLKASVW 222
+ATG D ++W V + + F+ H EI L+ P LV G D A +W
Sbjct: 150 IATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLW 204
Score = 32.0 bits (71), Expect = 1.1
Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 1/65 (1%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG-RDLK 218
+ FN L TG +D R+W + + + + H EI A G +V G +D
Sbjct: 351 ISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNT 410
Query: 219 ASVWQ 223
+W+
Sbjct: 411 CRIWR 415
Score = 31.6 bits (70), Expect = 1.4
Identities = 16/50 (32%), Positives = 24/50 (48%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211
FN D +L+ TG D ++W + + V H+ EI D GKL+
Sbjct: 269 FNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLI 318
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 45.4 bits (106), Expect = 9e-05
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Query: 161 CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKA 219
CF+ D +A+ G D ++V+K + EK+LE KAHE E+ A D + + T D K
Sbjct: 622 CFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKV 681
Query: 220 SVW 222
+W
Sbjct: 682 KIW 684
Score = 40.0 bits (92), Expect = 0.004
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 11/67 (16%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA---------HEGEIEDLALGPDGK-LV 211
F+ D+TLLATG +G +R+W V + E +L A H G + DL PDGK L+
Sbjct: 1092 FSVDSTLLATGDDNGEIRIWNVSNGE-LLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1150
Query: 212 TVGRDLK 218
+ G +K
Sbjct: 1151 SAGGYIK 1157
Score = 36.2 bits (82), Expect = 0.057
Identities = 46/224 (20%), Positives = 79/224 (35%), Gaps = 31/224 (13%)
Query: 139 LRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGE 198
L + N + Q+ F + F D L + D ++VW L+K + + H+
Sbjct: 945 LELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNW-QLDKCIFLRGHQET 1003
Query: 199 IEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQV-PD 257
++D L + +L++ D VW + + + T S + A +F D
Sbjct: 1004 VKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSAD 1063
Query: 258 QPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGL 317
+ A + F + +P LR C V C S T L
Sbjct: 1064 KTAKIWSFDLLLPLHELRGHNGC----------------------VRCSAFSVDSTLLAT 1101
Query: 318 GTVTGSVAIYIAFSLQCLYYV-------REAHGIVVTDVAFLPE 354
G G + I+ + + L+ HG VTD+ F P+
Sbjct: 1102 GDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPD 1145
Score = 29.3 bits (64), Expect = 6.9
Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 4/59 (6%)
Query: 157 QKVVCFNHDNT----LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211
++V C + N+ LLATG +D ++++W + E H + PD KL+
Sbjct: 700 EQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLL 758
Score = 28.9 bits (63), Expect = 9.0
Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK 209
+CF+ D +L + G GY++ W V + E F + ++ + + PD K
Sbjct: 1140 LCFSPDGKMLISAG--GYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFK 1187
>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
sapiens]
Length = 1248
Score = 45.4 bits (106), Expect = 9e-05
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Query: 161 CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKA 219
CF+ D +A+ G D ++V+K + EK+LE KAHE E+ A D + + T D K
Sbjct: 622 CFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKV 681
Query: 220 SVW 222
+W
Sbjct: 682 KIW 684
Score = 40.0 bits (92), Expect = 0.004
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 11/67 (16%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA---------HEGEIEDLALGPDGK-LV 211
F+ D+TLLATG +G +R+W V + E +L A H G + DL PDGK L+
Sbjct: 1135 FSVDSTLLATGDDNGEIRIWNVSNGE-LLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1193
Query: 212 TVGRDLK 218
+ G +K
Sbjct: 1194 SAGGYIK 1200
Score = 36.2 bits (82), Expect = 0.057
Identities = 46/224 (20%), Positives = 79/224 (35%), Gaps = 31/224 (13%)
Query: 139 LRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGE 198
L + N + Q+ F + F D L + D ++VW L+K + + H+
Sbjct: 988 LELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNW-QLDKCIFLRGHQET 1046
Query: 199 IEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQV-PD 257
++D L + +L++ D VW + + + T S + A +F D
Sbjct: 1047 VKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSAD 1106
Query: 258 QPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGL 317
+ A + F + +P LR C V C S T L
Sbjct: 1107 KTAKIWSFDLLLPLHELRGHNGC----------------------VRCSAFSVDSTLLAT 1144
Query: 318 GTVTGSVAIYIAFSLQCLYYV-------REAHGIVVTDVAFLPE 354
G G + I+ + + L+ HG VTD+ F P+
Sbjct: 1145 GDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPD 1188
Score = 29.3 bits (64), Expect = 6.9
Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 4/59 (6%)
Query: 157 QKVVCFNHDNT----LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211
++V C + N+ LLATG +D ++++W + E H + PD KL+
Sbjct: 700 EQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLL 758
Score = 28.9 bits (63), Expect = 9.0
Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK 209
+CF+ D +L + G GY++ W V + E F + ++ + + PD K
Sbjct: 1183 LCFSPDGKMLISAG--GYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFK 1230
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 45.4 bits (106), Expect = 9e-05
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Query: 161 CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKA 219
CF+ D +A+ G D ++V+K + EK+LE KAHE E+ A D + + T D K
Sbjct: 611 CFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKV 670
Query: 220 SVW 222
+W
Sbjct: 671 KIW 673
Score = 40.0 bits (92), Expect = 0.004
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 11/67 (16%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA---------HEGEIEDLALGPDGK-LV 211
F+ D+TLLATG +G +R+W V + E +L A H G + DL PDGK L+
Sbjct: 1081 FSVDSTLLATGDDNGEIRIWNVSNGE-LLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1139
Query: 212 TVGRDLK 218
+ G +K
Sbjct: 1140 SAGGYIK 1146
Score = 36.2 bits (82), Expect = 0.057
Identities = 46/224 (20%), Positives = 79/224 (35%), Gaps = 31/224 (13%)
Query: 139 LRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGE 198
L + N + Q+ F + F D L + D ++VW L+K + + H+
Sbjct: 934 LELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNW-QLDKCIFLRGHQET 992
Query: 199 IEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQV-PD 257
++D L + +L++ D VW + + + T S + A +F D
Sbjct: 993 VKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSAD 1052
Query: 258 QPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGL 317
+ A + F + +P LR C V C S T L
Sbjct: 1053 KTAKIWSFDLLLPLHELRGHNGC----------------------VRCSAFSVDSTLLAT 1090
Query: 318 GTVTGSVAIYIAFSLQCLYYV-------REAHGIVVTDVAFLPE 354
G G + I+ + + L+ HG VTD+ F P+
Sbjct: 1091 GDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPD 1134
Score = 29.3 bits (64), Expect = 6.9
Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 4/59 (6%)
Query: 157 QKVVCFNHDNT----LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211
++V C + N+ LLATG +D ++++W + E H + PD KL+
Sbjct: 689 EQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLL 747
Score = 28.9 bits (63), Expect = 9.0
Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK 209
+CF+ D +L + G GY++ W V + E F + ++ + + PD K
Sbjct: 1129 LCFSPDGKMLISAG--GYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFK 1176
>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
sapiens]
Length = 1237
Score = 45.4 bits (106), Expect = 9e-05
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Query: 161 CFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKA 219
CF+ D +A+ G D ++V+K + EK+LE KAHE E+ A D + + T D K
Sbjct: 611 CFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKV 670
Query: 220 SVW 222
+W
Sbjct: 671 KIW 673
Score = 40.0 bits (92), Expect = 0.004
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 11/67 (16%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA---------HEGEIEDLALGPDGK-LV 211
F+ D+TLLATG +G +R+W V + E +L A H G + DL PDGK L+
Sbjct: 1124 FSVDSTLLATGDDNGEIRIWNVSNGE-LLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1182
Query: 212 TVGRDLK 218
+ G +K
Sbjct: 1183 SAGGYIK 1189
Score = 36.2 bits (82), Expect = 0.057
Identities = 46/224 (20%), Positives = 79/224 (35%), Gaps = 31/224 (13%)
Query: 139 LRVENLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGE 198
L + N + Q+ F + F D L + D ++VW L+K + + H+
Sbjct: 977 LELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNW-QLDKCIFLRGHQET 1035
Query: 199 IEDLALGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQV-PD 257
++D L + +L++ D VW + + + T S + A +F D
Sbjct: 1036 VKDFRLLKNSRLLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSAD 1095
Query: 258 QPAGLRLFTVQIPHKRLRQPPPCYLTAWDGSNFLPLRTKSCGHEVVSCLDVSESGTFLGL 317
+ A + F + +P LR C V C S T L
Sbjct: 1096 KTAKIWSFDLLLPLHELRGHNGC----------------------VRCSAFSVDSTLLAT 1133
Query: 318 GTVTGSVAIYIAFSLQCLYYV-------REAHGIVVTDVAFLPE 354
G G + I+ + + L+ HG VTD+ F P+
Sbjct: 1134 GDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPD 1177
Score = 29.3 bits (64), Expect = 6.9
Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 4/59 (6%)
Query: 157 QKVVCFNHDNT----LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV 211
++V C + N+ LLATG +D ++++W + E H + PD KL+
Sbjct: 689 EQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLL 747
Score = 28.9 bits (63), Expect = 9.0
Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK 209
+CF+ D +L + G GY++ W V + E F + ++ + + PD K
Sbjct: 1172 LCFSPDGKMLISAG--GYIKWWNVVTGESSQTFYTNGTNLKKIHVSPDFK 1219
>gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1
[Homo sapiens]
Length = 1129
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/200 (20%), Positives = 76/200 (38%), Gaps = 14/200 (7%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP-DGKLVTVGRDLK 218
V FN D T +A G +D V++ V + F+ H+ + L+ P D L + D
Sbjct: 100 VVFNGDGTKIAAGSSDFLVKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGS 159
Query: 219 ASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPP 278
VWQ + W P A ++ QP +L + +
Sbjct: 160 VRVWQISDQTCAISW----PLLQKCNDVINAKSICRLAWQPKSGKLLAIPVEKSVKLYRR 215
Query: 279 PCYLTAWD-GSNFLPLRTKSCGHEVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYY 337
+ +D NF+ + ++ + S G +L G++ G + ++ + C+
Sbjct: 216 ESWSHQFDLSDNFI--------SQTLNIVTWSPCGQYLAAGSINGLIIVWNVETKDCMER 267
Query: 338 VREAHGIVVTDVAFLPEKGR 357
V+ G + +A+ P GR
Sbjct: 268 VKHEKGYAICGLAWHPTCGR 287
Score = 29.3 bits (64), Expect = 6.9
Identities = 10/23 (43%), Positives = 16/23 (69%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWK 182
VCF+ + + T G+DG VR+W+
Sbjct: 19 VCFDDSGSFIVTCGSDGDVRIWE 41
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTV--GRDLKA 219
F D LLATG +G +++W V + + +L H + DL PDG L+ V RD
Sbjct: 136 FGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTL 195
Query: 220 SVW 222
VW
Sbjct: 196 RVW 198
Score = 31.2 bits (69), Expect = 1.8
Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKAS 220
F+ D+++L + G V +W + + + + H ++ PDG L+ T D +
Sbjct: 222 FSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVY 281
Query: 221 VW 222
+W
Sbjct: 282 IW 283
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 42.7 bits (99), Expect = 6e-04
Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 19/149 (12%)
Query: 84 AGQDAHC--QLLRFQAHQQQGNKAEKAGSKEQGPRQRKGAAPAEKKCGAETQHEGLELRV 141
A HC +L+ + +Q K +A S+ + +P EK GL
Sbjct: 42 AWSQGHCIVKLIPWPLEEQFIPKGFEAKSRSSKNETKGRGSPKEKTLDCGQIVWGLAF-- 99
Query: 142 ENLQAVQTDFSSDPLQKVVCFNHDNT------LLATGGTDGYVRVWKVPSLEKVLEFKAH 195
+ + S P +K+ +H +LATG DG +++W+V + +L H
Sbjct: 100 -------SPWPSPPSRKLWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGH 152
Query: 196 EGEIEDLALGPDGKLVTV--GRDLKASVW 222
+ + DL+ P G L+ V RD +W
Sbjct: 153 QDVVRDLSFTPSGSLILVSASRDKTLRIW 181
Score = 33.9 bits (76), Expect = 0.28
Identities = 31/130 (23%), Positives = 49/130 (37%), Gaps = 7/130 (5%)
Query: 143 NLQAVQTDFSSDPLQKVVC--FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIE 200
N Q S LQ V C + D ++L + + V +W + S + + + H+ +
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVV 243
Query: 201 DLALGPDGK-LVTVGRDLKASVWQ--KDQLVTQLHWQENGPTFSSTPYRYQACRFGQVPD 257
PD LVT D +W + + LH + P + + R V
Sbjct: 244 SCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLR--SVCF 301
Query: 258 QPAGLRLFTV 267
P GL L TV
Sbjct: 302 SPEGLYLATV 311
>gi|16445438 bromodomain and WD repeat domain containing 1 isoform B
[Homo sapiens]
Length = 2269
Score = 42.4 bits (98), Expect = 8e-04
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-----LVTVGRDL 217
N++NT++A G D +RVW + + V + H G I L P K +V+ G D
Sbjct: 237 NYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADG 296
Query: 218 KASVWQKD 225
WQ D
Sbjct: 297 TVCFWQWD 304
Score = 32.3 bits (72), Expect = 0.82
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 156 LQKVVCFNHDNT--LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTV 213
L V C D T + TG D V++W + + + H EI D+A+ + ++
Sbjct: 186 LSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAA 245
Query: 214 GR-DLKASVW 222
G D VW
Sbjct: 246 GSCDKIIRVW 255
>gi|16445436 bromodomain and WD repeat domain containing 1 isoform A
[Homo sapiens]
Length = 2320
Score = 42.4 bits (98), Expect = 8e-04
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
Query: 163 NHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-----LVTVGRDL 217
N++NT++A G D +RVW + + V + H G I L P K +V+ G D
Sbjct: 237 NYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADG 296
Query: 218 KASVWQKD 225
WQ D
Sbjct: 297 TVCFWQWD 304
Score = 32.3 bits (72), Expect = 0.82
Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 156 LQKVVCFNHDNT--LLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTV 213
L V C D T + TG D V++W + + + H EI D+A+ + ++
Sbjct: 186 LSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAA 245
Query: 214 GR-DLKASVW 222
G D VW
Sbjct: 246 GSCDKIIRVW 255
>gi|55769546 PAK1 interacting protein 1 [Homo sapiens]
Length = 392
Score = 42.0 bits (97), Expect = 0.001
Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASVW 222
+ N L +G DG + +W E + KAH+G++ L++ P GKL ++VG D W
Sbjct: 91 YGNRHLISGAEDGLICIWDAKKWECLKSIKAHKGQVTFLSIHPSGKLALSVGTDKTLRTW 150
Score = 30.4 bits (67), Expect = 3.1
Identities = 13/36 (36%), Positives = 22/36 (61%)
Query: 167 TLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDL 202
++LA G + +R + SL + EFKAHE ++D+
Sbjct: 216 SVLAVAGDEEVIRFFDCDSLVCLCEFKAHENRVKDM 251
>gi|55743075 angio-associated, migratory cell protein [Homo sapiens]
Length = 434
Score = 41.6 bits (96), Expect = 0.001
Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 2/53 (3%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214
F+HD+TL+ATG G ++VW+V + E+V F+A G++E + P ++ G
Sbjct: 142 FSHDSTLVATGDMSGLLKVWQVDTKEEVWSFEA--GDLEWMEWHPRAPVLLAG 192
Score = 35.4 bits (80), Expect = 0.097
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 159 VVCFNHD---NTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR 215
V C + D NTL TGG D VW++ E + E H+ + D LV G
Sbjct: 94 VFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATG- 152
Query: 216 DLKA--SVWQKD 225
D+ VWQ D
Sbjct: 153 DMSGLLKVWQVD 164
Score = 35.4 bits (80), Expect = 0.097
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 171 TGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASVW 222
T DG VR+W + + +++ H EI D AL D L VT D KA V+
Sbjct: 375 TCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSGDHKAKVF 427
>gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo
sapiens]
Length = 513
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 145 QAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEF-KAHEGEIEDLA 203
QA D +CF+ D +LATG DG ++VWK+ S + + F +AH + L+
Sbjct: 255 QAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLS 314
Query: 204 LGPDGKLVTVGRDLKASVWQKDQLVTQLHWQENGPT 239
D + L AS DQ + ++H ++G T
Sbjct: 315 FSKDSSQI-----LSASF---DQTI-RIHGLKSGKT 341
Score = 30.4 bits (67), Expect = 3.1
Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 9/71 (12%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPS--LEKVLEFKAHEG--EIEDLAL----GPDGKLVTV 213
F+ D L TG DG++ VW + + K L+++A + ++D L D +++
Sbjct: 222 FSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLAT 281
Query: 214 G-RDLKASVWQ 223
G +D K VW+
Sbjct: 282 GAQDGKIKVWK 292
>gi|189571685 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 40.4 bits (93), Expect = 0.003
Identities = 58/219 (26%), Positives = 84/219 (38%), Gaps = 28/219 (12%)
Query: 146 AVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALG 205
AV S P+ +V F+ D+T LA+G DG V +W S + +G + A
Sbjct: 90 AVMEQPSGSPV-RVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFS 148
Query: 206 PDGKLVTVGRDL-KASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVP--DQPAGL 262
P+G G +VW D + LH E T C F P D GL
Sbjct: 149 PNGSFFVTGSSCGDLTVW--DDKMRCLH-SEKAHDLGIT-----CCDFSSQPVSDGEQGL 200
Query: 263 RLFTVQIPHKRLRQPPPCYLTAWDGSNF------LPLRTKSCGH--EVVSCLDVSESGTF 314
+ F + + C + W S L ++ GH V++C S G
Sbjct: 201 QFFRLASCGQ------DCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLACA-FSHDGQM 253
Query: 315 LGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLP 353
L G+V SV +Y + L+ + + H VT AF P
Sbjct: 254 LVSGSVDKSVIVYDTNTENILHTLTQ-HTRYVTTCAFAP 291
>gi|189571683 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 40.4 bits (93), Expect = 0.003
Identities = 58/219 (26%), Positives = 84/219 (38%), Gaps = 28/219 (12%)
Query: 146 AVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALG 205
AV S P+ +V F+ D+T LA+G DG V +W S + +G + A
Sbjct: 90 AVMEQPSGSPV-RVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFS 148
Query: 206 PDGKLVTVGRDL-KASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVP--DQPAGL 262
P+G G +VW D + LH E T C F P D GL
Sbjct: 149 PNGSFFVTGSSCGDLTVW--DDKMRCLH-SEKAHDLGIT-----CCDFSSQPVSDGEQGL 200
Query: 263 RLFTVQIPHKRLRQPPPCYLTAWDGSNF------LPLRTKSCGH--EVVSCLDVSESGTF 314
+ F + + C + W S L ++ GH V++C S G
Sbjct: 201 QFFRLASCGQ------DCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLACA-FSHDGQM 253
Query: 315 LGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLP 353
L G+V SV +Y + L+ + + H VT AF P
Sbjct: 254 LVSGSVDKSVIVYDTNTENILHTLTQ-HTRYVTTCAFAP 291
>gi|189571681 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 40.4 bits (93), Expect = 0.003
Identities = 58/219 (26%), Positives = 84/219 (38%), Gaps = 28/219 (12%)
Query: 146 AVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALG 205
AV S P+ +V F+ D+T LA+G DG V +W S + +G + A
Sbjct: 90 AVMEQPSGSPV-RVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFS 148
Query: 206 PDGKLVTVGRDL-KASVWQKDQLVTQLHWQENGPTFSSTPYRYQACRFGQVP--DQPAGL 262
P+G G +VW D + LH E T C F P D GL
Sbjct: 149 PNGSFFVTGSSCGDLTVW--DDKMRCLH-SEKAHDLGIT-----CCDFSSQPVSDGEQGL 200
Query: 263 RLFTVQIPHKRLRQPPPCYLTAWDGSNF------LPLRTKSCGH--EVVSCLDVSESGTF 314
+ F + + C + W S L ++ GH V++C S G
Sbjct: 201 QFFRLASCGQ------DCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLACA-FSHDGQM 253
Query: 315 LGLGTVTGSVAIYIAFSLQCLYYVREAHGIVVTDVAFLP 353
L G+V SV +Y + L+ + + H VT AF P
Sbjct: 254 LVSGSVDKSVIVYDTNTENILHTLTQ-HTRYVTTCAFAP 291
>gi|209969680 Fzr1 protein isoform 1 [Homo sapiens]
Length = 496
Score = 40.0 bits (92), Expect = 0.004
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 164 HDNTLLATGG-TDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214
H N L++T G + + VWK PSL +V + H + LA+ PDG+ + G
Sbjct: 410 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTG 461
Score = 34.7 bits (78), Expect = 0.16
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 12/72 (16%)
Query: 147 VQTDFSSDPLQ---------KVVC---FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA 194
+Q D + PLQ + VC ++ D+ LLA+GG D + VW SL V ++
Sbjct: 294 LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTE 353
Query: 195 HEGEIEDLALGP 206
H ++ +A P
Sbjct: 354 HLAAVKAIAWSP 365
>gi|209969678 Fzr1 protein isoform 3 [Homo sapiens]
Length = 404
Score = 40.0 bits (92), Expect = 0.004
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 164 HDNTLLATGG-TDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214
H N L++T G + + VWK PSL +V + H + LA+ PDG+ + G
Sbjct: 321 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTG 372
Score = 34.7 bits (78), Expect = 0.16
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 12/72 (16%)
Query: 147 VQTDFSSDPLQ---------KVVC---FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA 194
+Q D + PLQ + VC ++ D+ LLA+GG D + VW SL V ++
Sbjct: 205 LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTE 264
Query: 195 HEGEIEDLALGP 206
H ++ +A P
Sbjct: 265 HLAAVKAIAWSP 276
>gi|33620742 Fzr1 protein isoform 2 [Homo sapiens]
Length = 493
Score = 40.0 bits (92), Expect = 0.004
Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 164 HDNTLLATGG-TDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214
H N L++T G + + VWK PSL +V + H + LA+ PDG+ + G
Sbjct: 410 HANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTG 461
Score = 34.7 bits (78), Expect = 0.16
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 12/72 (16%)
Query: 147 VQTDFSSDPLQ---------KVVC---FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKA 194
+Q D + PLQ + VC ++ D+ LLA+GG D + VW SL V ++
Sbjct: 294 LQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTE 353
Query: 195 HEGEIEDLALGP 206
H ++ +A P
Sbjct: 354 HLAAVKAIAWSP 365
>gi|21281677 WD repeat domain 36 [Homo sapiens]
Length = 951
Score = 39.7 bits (91), Expect = 0.005
Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Query: 152 SSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-L 210
SS P ++ + D+ +L D + V + + + V EF H+G+I D+A PDG+ L
Sbjct: 580 SSSP--NIMLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPDGRWL 637
Query: 211 VTVGRDLKASVW 222
++ D W
Sbjct: 638 ISAAMDCSIRTW 649
>gi|4759276 RNA, U3 small nucleolar interacting protein 2 [Homo
sapiens]
Length = 475
Score = 39.7 bits (91), Expect = 0.005
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLKASVW 222
+ GG DG VRVWK+P E L F H+G I+ + L + +V+ D ++W
Sbjct: 298 VTAGGRDGTVRVWKIPE-ESQLVFYGHQGSIDCIHLINEEHMVSGADDGSVALW 350
>gi|48928050 F-box and WD repeat domain containing 11 isoform C
[Homo sapiens]
Length = 542
Score = 39.3 bits (90), Expect = 0.007
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 159 VVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLK 218
V+C +D ++ TG +D VRVW V + E VL H E +G +VT +D
Sbjct: 283 VLCLQYDERVIVTGSSDSTVRVWDVNTGE-VLNTLIHHNEAVLHLRFSNGLMVTCSKDRS 341
Query: 219 ASVW 222
+VW
Sbjct: 342 IAVW 345
Score = 35.8 bits (81), Expect = 0.074
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 143 NLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDL 202
NLQ +Q S+ + V C +D+ + +G D +++W SLE + H G + L
Sbjct: 229 NLQRIQC--RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--L 284
Query: 203 ALGPDGKLVTVG-RDLKASVWQ---KDQLVTQLHWQE 235
L D +++ G D VW + L T +H E
Sbjct: 285 CLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNE 321
>gi|48928048 F-box and WD repeat domain containing 11 isoform A
[Homo sapiens]
Length = 508
Score = 39.3 bits (90), Expect = 0.007
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 159 VVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLK 218
V+C +D ++ TG +D VRVW V + E VL H E +G +VT +D
Sbjct: 249 VLCLQYDERVIVTGSSDSTVRVWDVNTGE-VLNTLIHHNEAVLHLRFSNGLMVTCSKDRS 307
Query: 219 ASVW 222
+VW
Sbjct: 308 IAVW 311
Score = 35.8 bits (81), Expect = 0.074
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 143 NLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDL 202
NLQ +Q S+ + V C +D+ + +G D +++W SLE + H G + L
Sbjct: 195 NLQRIQC--RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--L 250
Query: 203 ALGPDGKLVTVG-RDLKASVWQ---KDQLVTQLHWQE 235
L D +++ G D VW + L T +H E
Sbjct: 251 CLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNE 287
>gi|48928046 F-box and WD repeat domain containing 11 isoform B
[Homo sapiens]
Length = 529
Score = 39.3 bits (90), Expect = 0.007
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 159 VVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGRDLK 218
V+C +D ++ TG +D VRVW V + E VL H E +G +VT +D
Sbjct: 270 VLCLQYDERVIVTGSSDSTVRVWDVNTGE-VLNTLIHHNEAVLHLRFSNGLMVTCSKDRS 328
Query: 219 ASVW 222
+VW
Sbjct: 329 IAVW 332
Score = 35.8 bits (81), Expect = 0.074
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 8/97 (8%)
Query: 143 NLQAVQTDFSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDL 202
NLQ +Q S+ + V C +D+ + +G D +++W SLE + H G + L
Sbjct: 216 NLQRIQC--RSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--L 271
Query: 203 ALGPDGKLVTVG-RDLKASVWQ---KDQLVTQLHWQE 235
L D +++ G D VW + L T +H E
Sbjct: 272 CLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNE 308
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 38.9 bits (89), Expect = 0.009
Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG-RDLKAS 220
F+ ++ +ATG D VR+W V + V F H+G I L P+G+ + G D +
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVL 694
Query: 221 VW 222
+W
Sbjct: 695 LW 696
Score = 36.2 bits (82), Expect = 0.057
Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDG-KLVTVGRDLKAS 220
F+ D L + DG VR+W + + ++ +K H + D P G V+ G D A
Sbjct: 551 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVAR 610
Query: 221 VWQKD 225
+W D
Sbjct: 611 LWATD 615
Score = 35.0 bits (79), Expect = 0.13
Identities = 18/53 (33%), Positives = 26/53 (49%)
Query: 162 FNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVG 214
F+ + LATG TDG V +W + V E K H + L DG+++ G
Sbjct: 677 FSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASG 729
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 38.9 bits (89), Expect = 0.009
Identities = 42/185 (22%), Positives = 74/185 (40%), Gaps = 21/185 (11%)
Query: 58 SASLLHSHDTETRATMNLALAGD---ILAAGQDAHCQLLRFQAHQQQGNKAEKAGSKEQG 114
S +LL + D A +++L+ D + G D + F+ + + + ++ K+
Sbjct: 485 SGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTR 544
Query: 115 PRQRKGAAPAEKKCGAETQHEGLELRVENLQAVQTDFSSDPLQ----------KVVCFN- 163
Q + C + + ++ L L V L F D L+ V+C +
Sbjct: 545 TLQ----LDEDVLCVSYSPNQKL-LAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDI 599
Query: 164 -HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKL-VTVGRDLKASV 221
HD L+ATG D V++W + + AH+ + L P L T G+D K
Sbjct: 600 SHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQ 659
Query: 222 WQKDQ 226
W D+
Sbjct: 660 WDADK 664
Score = 32.7 bits (73), Expect = 0.63
Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 1/75 (1%)
Query: 151 FSSDPLQKVVCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK- 209
F+ D + F + L T G D ++ W E + + H EI LA+ P G
Sbjct: 630 FAHDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDY 689
Query: 210 LVTVGRDLKASVWQK 224
+V+ D +W++
Sbjct: 690 VVSSSHDKSLRLWER 704
Score = 30.8 bits (68), Expect = 2.4
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGP-DGKLVTVGRDLK 218
+C + D LA G DG +R++ + S E + F H+ I L G+L + +D
Sbjct: 71 LCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTD 130
Query: 219 ASVW 222
VW
Sbjct: 131 IIVW 134
Score = 29.6 bits (65), Expect = 5.3
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEI-EDLALGPDGKLVTVGRDLKASVWQKD 225
LA+G D + VW V + + K H+ I + L L LVT G+D W D
Sbjct: 122 LASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLD 179
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 38.9 bits (89), Expect = 0.009
Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLVTVGR-DLK 218
+ F+ D +L TGG D + RVW + + ++ + H EI + P+G + G D
Sbjct: 371 IAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNT 430
Query: 219 ASVWQKDQ 226
VW Q
Sbjct: 431 CKVWDLRQ 438
Score = 35.4 bits (80), Expect = 0.097
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 164 HDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLKASVW 222
H N LL TG D ++W P + HEG++ L + DG+L+ T D +W
Sbjct: 461 HGNFLL-TGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLW 519
Query: 223 QKD 225
+
Sbjct: 520 MAE 522
Score = 31.6 bits (70), Expect = 1.4
Identities = 43/195 (22%), Positives = 71/195 (36%), Gaps = 35/195 (17%)
Query: 169 LATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGK-LVTVGRDLKASVWQKDQL 227
LA+ DG V++W + S E V + + H + + P G+ L T D +W +
Sbjct: 296 LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQ 355
Query: 228 VTQLHWQENGPTFSSTPYRYQACRFGQVPDQPAGLRLFTVQIPHKRLRQPPPCYLTAWDG 287
LH + + + G GL F WD
Sbjct: 356 EEILHQEGHSMGVYDIAFHQDGSLAG-----TGGLDAFG----------------RVWD- 393
Query: 288 SNFLPLRTKSC-----GH-EVVSCLDVSESGTFLGLGTVTGSVAIYIAFSLQCLYYVREA 341
LRT C GH + + ++ S +G + G+ + ++ +C+Y + A
Sbjct: 394 -----LRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTI-PA 447
Query: 342 HGIVVTDVAFLPEKG 356
H +VT V F P G
Sbjct: 448 HQNLVTGVKFEPIHG 462
Score = 30.8 bits (68), Expect = 2.4
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 160 VCFNHDNTLLATGGTDGYVRVWKVPSLEKVLEFKAHEGEIEDLALGPDGKLV-TVGRDLK 218
V ++ L T D R+W + + E++L + H + D+A DG L T G D
Sbjct: 329 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAF 388
Query: 219 ASVW 222
VW
Sbjct: 389 GRVW 392
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,303,442
Number of Sequences: 37866
Number of extensions: 810317
Number of successful extensions: 3077
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 109
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 2495
Number of HSP's gapped (non-prelim): 622
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.