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Search of human proteins with 13775222
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13775222 MAX dimerization protein 3 isoform a [Homo sapiens]
(206 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13775222 MAX dimerization protein 3 isoform a [Homo sapiens] 407 e-114
gi|219283190 MAX dimerization protein 3 isoform b [Homo sapiens] 330 5e-91
gi|57242782 MAX interactor 1 isoform a [Homo sapiens] 165 2e-41
gi|4505069 MAX dimerization protein 1 [Homo sapiens] 159 2e-39
gi|47717116 MAX interactor 1 isoform b [Homo sapiens] 153 9e-38
gi|5453734 MAD4 [Homo sapiens] 147 6e-36
gi|57242784 MAX interactor 1 isoform c [Homo sapiens] 117 7e-27
gi|9945318 MAX binding protein [Homo sapiens] 62 3e-10
gi|74315997 l-myc-1 proto-oncogene isoform 1 [Homo sapiens] 52 3e-07
gi|74315995 l-myc-1 proto-oncogene isoform 1 [Homo sapiens] 52 3e-07
gi|71774083 myc proto-oncogene protein [Homo sapiens] 52 3e-07
gi|19923312 v-myc myelocytomatosis viral related oncogene, neuro... 46 3e-05
gi|8659574 transcription factor E3 [Homo sapiens] 43 2e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 42 5e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 42 5e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 42 5e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 42 5e-04
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 42 5e-04
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 42 5e-04
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 42 5e-04
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 42 5e-04
gi|38156705 microphthalmia-associated transcription factor isofo... 40 0.001
gi|38156703 microphthalmia-associated transcription factor isofo... 40 0.001
gi|38156701 microphthalmia-associated transcription factor isofo... 40 0.001
gi|38156699 microphthalmia-associated transcription factor isofo... 40 0.001
gi|38156697 microphthalmia-associated transcription factor isofo... 40 0.001
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 40 0.001
gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isofo... 40 0.002
gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isofor... 40 0.002
gi|195947367 golgi autoantigen, golgin subfamily a, 8B [Homo sap... 39 0.002
>gi|13775222 MAX dimerization protein 3 isoform a [Homo sapiens]
Length = 206
Score = 407 bits (1045), Expect = e-114
Identities = 206/206 (100%), Positives = 206/206 (100%)
Query: 1 MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRS 60
MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRS
Sbjct: 1 MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRS 60
Query: 61 VHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLK 120
VHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLK
Sbjct: 61 VHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLK 120
Query: 121 ERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVF 180
ERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVF
Sbjct: 121 ERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVF 180
Query: 181 GGEAELLRGFVAGQEHSYSHGGGAWL 206
GGEAELLRGFVAGQEHSYSHGGGAWL
Sbjct: 181 GGEAELLRGFVAGQEHSYSHGGGAWL 206
>gi|219283190 MAX dimerization protein 3 isoform b [Homo sapiens]
Length = 193
Score = 330 bits (846), Expect = 5e-91
Identities = 168/168 (100%), Positives = 168/168 (100%)
Query: 1 MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRS 60
MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRS
Sbjct: 1 MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRS 60
Query: 61 VHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLK 120
VHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLK
Sbjct: 61 VHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLK 120
Query: 121 ERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQ 168
ERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQ
Sbjct: 121 ERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQ 168
>gi|57242782 MAX interactor 1 isoform a [Homo sapiens]
Length = 228
Score = 165 bits (418), Expect = 2e-41
Identities = 94/189 (49%), Positives = 126/189 (66%), Gaps = 14/189 (7%)
Query: 7 NIQVLLQAAEFLERREREAEHGYASLCPH---------RSPGPIHRRKKRPPQAPGAQDS 57
N+Q LL+AAEFLERRERE EHGYAS P + P + R +K + +
Sbjct: 8 NVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTA 67
Query: 58 GRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRAR 117
RS HNELEK RRA L+ CLERLK +PLG DC R+TTL LL +A+ HI+KLE+ E++++
Sbjct: 68 NRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQ 127
Query: 118 QLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVES 177
E L +Q+ L+ +LEQL+ G E ER+R DS+ S+ +SS+RSDS++EE+EVDVES
Sbjct: 128 HQLENLEREQRFLKWRLEQLQ---GPQEMERIRMDSIGST-ISSDRSDSEREEIEVDVES 183
Query: 178 LVFG-GEAE 185
F GE +
Sbjct: 184 TEFSHGEVD 192
>gi|4505069 MAX dimerization protein 1 [Homo sapiens]
Length = 221
Score = 159 bits (402), Expect = 2e-39
Identities = 89/171 (52%), Positives = 127/171 (74%), Gaps = 10/171 (5%)
Query: 7 NIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELE 66
NIQ+LL+AA++LERREREAEHGYAS+ P+ + KR ++ S RS HNE+E
Sbjct: 8 NIQMLLEAADYLERREREAEHGYASMLPYNNKD--RDALKRRNKSKKNNSSSRSTHNEME 65
Query: 67 KRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSK 126
K RRA L+ CLE+LK +PLG + +R+TTLSLL +A++HI+KLED +++A ++L+ +
Sbjct: 66 KNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQRE 125
Query: 127 QQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVES 177
Q+ L+RQLE+L G+ ER+R DS+ S+ +SSERSDSD+EE++VDVES
Sbjct: 126 QRHLKRQLEKL-GI------ERIRMDSIGST-VSSERSDSDREEIDVDVES 168
>gi|47717116 MAX interactor 1 isoform b [Homo sapiens]
Length = 295
Score = 153 bits (387), Expect = 9e-38
Identities = 89/192 (46%), Positives = 125/192 (65%), Gaps = 17/192 (8%)
Query: 7 NIQVLLQAAEFLERRERE---AEHGYASLCPH---------RSPGPIHRRKKRPPQAPGA 54
N+Q+LL+AA +LE+ E+E EHGYAS P + P + R +K +
Sbjct: 72 NVQILLEAASYLEQIEKENKKCEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT 131
Query: 55 QDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQ 114
+ RS HNELEK RRA L+ CLERLK +PLG DC R+TTL LL +A+ HI+KLE+ E+
Sbjct: 132 STANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAER 191
Query: 115 RARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVD 174
+++ E L +Q+ L+ +LEQL+ G E ER+R DS+ S+ +SS+RSDS++EE+EVD
Sbjct: 192 KSQHQLENLEREQRFLKWRLEQLQ---GPQEMERIRMDSIGST-ISSDRSDSEREEIEVD 247
Query: 175 VESLVFG-GEAE 185
VES F GE +
Sbjct: 248 VESTEFSHGEVD 259
>gi|5453734 MAD4 [Homo sapiens]
Length = 209
Score = 147 bits (371), Expect = 6e-36
Identities = 86/192 (44%), Positives = 123/192 (64%), Gaps = 13/192 (6%)
Query: 6 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL 65
+++ +LL+AAE+LERR+REAEHGYAS+ P G R K + + RS HNEL
Sbjct: 4 NSLLILLEAAEYLERRDREAEHGYASVLPF--DGDFAREKTKAAGLVRKAPNNRSSHNEL 61
Query: 66 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS 125
EK RRA+L+ LE+LKQ +PLG D R+TTLSLL+RA++HI+KLE+Q++RA +KE+L+
Sbjct: 62 EKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQ 121
Query: 126 KQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFG-GEA 184
+ + L+R+LEQL ER+R DS S+ +D E EVD+E + FG GE
Sbjct: 122 EHRFLKRRLEQL----SVQSVERVRTDSTGSA------VSTDDSEQEVDIEGMEFGPGEL 171
Query: 185 ELLRGFVAGQEH 196
+ + +H
Sbjct: 172 DSVGSSSDADDH 183
>gi|57242784 MAX interactor 1 isoform c [Homo sapiens]
Length = 182
Score = 117 bits (293), Expect = 7e-27
Identities = 68/149 (45%), Positives = 95/149 (63%), Gaps = 5/149 (3%)
Query: 38 PGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLS 97
P P + K P + AQ N RRA L+ CLERLK +PLG DC R+TTL
Sbjct: 2 PSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRRAHLRLCLERLKVLIPLGPDCTRHTTLG 61
Query: 98 LLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSS 157
LL +A+ HI+KLE+ E++++ E L +Q+ L+ +LEQL+ G E ER+R DS+ S+
Sbjct: 62 LLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQ---GPQEMERIRMDSIGST 118
Query: 158 GLSSERSDSDQEELEVDVESLVFG-GEAE 185
+SS+RSDS++EE+EVDVES F GE +
Sbjct: 119 -ISSDRSDSEREEIEVDVESTEFSHGEVD 146
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 62.0 bits (149), Expect = 3e-10
Identities = 43/126 (34%), Positives = 67/126 (53%), Gaps = 11/126 (8%)
Query: 59 RSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQ 118
R VHN+LEK RRA LK C E LK+ +P D + + LS+LR A +IQ L+ +E+
Sbjct: 222 REVHNKLEKNRRAHLKECFETLKRNIP-NVDDKKTSNLSVLRTALRYIQSLKRKEKEYEH 280
Query: 119 LKERLRSKQQSLQRQLEQLR----GLAGAAERERL------RADSLDSSGLSSERSDSDQ 168
ERL ++ + Q++L +L+ E +R+ D S+ +SE D+
Sbjct: 281 EMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNID 340
Query: 169 EELEVD 174
E++E D
Sbjct: 341 EDMEED 346
Score = 27.7 bits (60), Expect = 7.2
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 1/37 (2%)
Query: 97 SLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQ 133
+LL AR ++ Q+QRAR+ +ERLR +Q+ Q Q
Sbjct: 5 TLLEAARF-LEWQAQQQQRAREEQERLRLEQEREQEQ 40
>gi|74315997 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]
Length = 364
Score = 52.4 bits (124), Expect = 3e-07
Identities = 28/81 (34%), Positives = 46/81 (56%)
Query: 59 RSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQ 118
R HN LE++RR L+ L+ Q+P A C++ + +L +A ++Q L E+R
Sbjct: 283 RKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMAT 342
Query: 119 LKERLRSKQQSLQRQLEQLRG 139
K +LR +QQ LQ+++ L G
Sbjct: 343 EKRQLRCRQQQLQKRIAYLTG 363
>gi|74315995 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]
Length = 364
Score = 52.4 bits (124), Expect = 3e-07
Identities = 28/81 (34%), Positives = 46/81 (56%)
Query: 59 RSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQ 118
R HN LE++RR L+ L+ Q+P A C++ + +L +A ++Q L E+R
Sbjct: 283 RKNHNFLERKRRNDLRSRFLALRDQVPTLASCSKAPKVVILSKALEYLQALVGAEKRMAT 342
Query: 119 LKERLRSKQQSLQRQLEQLRG 139
K +LR +QQ LQ+++ L G
Sbjct: 343 EKRQLRCRQQQLQKRIAYLTG 363
>gi|71774083 myc proto-oncogene protein [Homo sapiens]
Length = 454
Score = 52.4 bits (124), Expect = 3e-07
Identities = 28/97 (28%), Positives = 56/97 (57%)
Query: 42 HRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRR 101
+R+ P + ++ R HN LE++RR +LKR L+ Q+P + + + +L++
Sbjct: 354 NRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKK 413
Query: 102 ARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLR 138
A +I ++ +EQ+ ++ LR +++ L+ +LEQLR
Sbjct: 414 ATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLR 450
>gi|19923312 v-myc myelocytomatosis viral related oncogene,
neuroblastoma derived [Homo sapiens]
Length = 464
Score = 45.8 bits (107), Expect = 3e-05
Identities = 28/109 (25%), Positives = 53/109 (48%)
Query: 30 ASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGAD 89
AS P +S P + P + R HN LE++RR L+ L+ +P
Sbjct: 354 ASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVK 413
Query: 90 CARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLR 138
+ + +L++A ++ L+ +E + KE+L+++QQ L +++E R
Sbjct: 414 NEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHAR 462
>gi|8659574 transcription factor E3 [Homo sapiens]
Length = 575
Score = 43.1 bits (100), Expect = 2e-04
Identities = 29/109 (26%), Positives = 58/109 (53%), Gaps = 4/109 (3%)
Query: 33 CPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCA- 91
CP P + +A + + HN +E+RRR + ++ L +P +D
Sbjct: 322 CPAELPNIKREISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEM 381
Query: 92 RYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQ---SLQRQLEQL 137
R+ ++L+ + +I+KL+ ++QR++ L+ R RS +Q SLQ ++++L
Sbjct: 382 RWNKGTILKASVDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQEL 430
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 41.6 bits (96), Expect = 5e-04
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 16/136 (11%)
Query: 41 IHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLR 100
+ R+K+ Q Q++ R + + ++++ AQ+K Q C TLSL
Sbjct: 883 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 942
Query: 101 RARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLS 160
IQKLE E+R RQL+E R +Q+ L + L+Q +++ + L G
Sbjct: 943 -----IQKLE--EERERQLREEQRRQQRELMKALQQ---------QQQQQQQKLSGWGNV 986
Query: 161 SERSDSDQEELEVDVE 176
S+ S + + LE+ E
Sbjct: 987 SKPSGTTKSLLEIQQE 1002
Score = 35.8 bits (81), Expect = 0.026
Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 8/114 (7%)
Query: 64 ELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERL 123
+LEK + A+L++ ER + +M + LRR + I + + +E+R R+ +E L
Sbjct: 722 QLEKAKAAKLEQ--ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 779
Query: 124 --RSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSD----QEEL 171
R ++++L+RQ EQ L E E + L R + + QEEL
Sbjct: 780 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 833
Score = 30.8 bits (68), Expect = 0.85
Identities = 45/181 (24%), Positives = 78/181 (43%), Gaps = 20/181 (11%)
Query: 2 EPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKK-----RPPQAPGAQD 56
E L + +L+ + ER+ RE E L + + R+++ R + +
Sbjct: 753 EELRRQQEEILRRQQEEERKRREEEE----LARRKQEEALRRQREQEIALRRQREEEERQ 808
Query: 57 SGRSVHNELEKRRRAQLKRCL--ERLKQQMPLGADCARYTTLSLLR----RARMHIQKLE 110
LE+RRR + +R E L++Q A AR + R R RM +
Sbjct: 809 QQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 868
Query: 111 ---DQEQRARQLKERLRSKQQSLQRQLEQ--LRGLAGAAERERLRADSLDSSGLSSERSD 165
++E+R R+ E R K+ QRQ +Q LR L ++++L L SS ++S+
Sbjct: 869 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 928
Query: 166 S 166
+
Sbjct: 929 T 929
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 41.6 bits (96), Expect = 5e-04
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 16/136 (11%)
Query: 41 IHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLR 100
+ R+K+ Q Q++ R + + ++++ AQ+K Q C TLSL
Sbjct: 910 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 969
Query: 101 RARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLS 160
IQKLE E+R RQL+E R +Q+ L + L+Q +++ + L G
Sbjct: 970 -----IQKLE--EERERQLREEQRRQQRELMKALQQ---------QQQQQQQKLSGWGNV 1013
Query: 161 SERSDSDQEELEVDVE 176
S+ S + + LE+ E
Sbjct: 1014 SKPSGTTKSLLEIQQE 1029
Score = 35.8 bits (81), Expect = 0.026
Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 8/114 (7%)
Query: 64 ELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERL 123
+LEK + A+L++ ER + +M + LRR + I + + +E+R R+ +E L
Sbjct: 749 QLEKAKAAKLEQ--ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 806
Query: 124 --RSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSD----QEEL 171
R ++++L+RQ EQ L E E + L R + + QEEL
Sbjct: 807 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 860
Score = 30.8 bits (68), Expect = 0.85
Identities = 45/181 (24%), Positives = 78/181 (43%), Gaps = 20/181 (11%)
Query: 2 EPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKK-----RPPQAPGAQD 56
E L + +L+ + ER+ RE E L + + R+++ R + +
Sbjct: 780 EELRRQQEEILRRQQEEERKRREEEE----LARRKQEEALRRQREQEIALRRQREEEERQ 835
Query: 57 SGRSVHNELEKRRRAQLKRCL--ERLKQQMPLGADCARYTTLSLLR----RARMHIQKLE 110
LE+RRR + +R E L++Q A AR + R R RM +
Sbjct: 836 QQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 895
Query: 111 ---DQEQRARQLKERLRSKQQSLQRQLEQ--LRGLAGAAERERLRADSLDSSGLSSERSD 165
++E+R R+ E R K+ QRQ +Q LR L ++++L L SS ++S+
Sbjct: 896 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 955
Query: 166 S 166
+
Sbjct: 956 T 956
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 41.6 bits (96), Expect = 5e-04
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 16/136 (11%)
Query: 41 IHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLR 100
+ R+K+ Q Q++ R + + ++++ AQ+K Q C TLSL
Sbjct: 889 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 948
Query: 101 RARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLS 160
IQKLE E+R RQL+E R +Q+ L + L+Q +++ + L G
Sbjct: 949 -----IQKLE--EERERQLREEQRRQQRELMKALQQ---------QQQQQQQKLSGWGNV 992
Query: 161 SERSDSDQEELEVDVE 176
S+ S + + LE+ E
Sbjct: 993 SKPSGTTKSLLEIQQE 1008
Score = 35.8 bits (81), Expect = 0.026
Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 8/114 (7%)
Query: 64 ELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERL 123
+LEK + A+L++ ER + +M + LRR + I + + +E+R R+ +E L
Sbjct: 728 QLEKAKAAKLEQ--ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 124 --RSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSD----QEEL 171
R ++++L+RQ EQ L E E + L R + + QEEL
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
Score = 30.8 bits (68), Expect = 0.85
Identities = 45/181 (24%), Positives = 78/181 (43%), Gaps = 20/181 (11%)
Query: 2 EPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKK-----RPPQAPGAQD 56
E L + +L+ + ER+ RE E L + + R+++ R + +
Sbjct: 759 EELRRQQEEILRRQQEEERKRREEEE----LARRKQEEALRRQREQEIALRRQREEEERQ 814
Query: 57 SGRSVHNELEKRRRAQLKRCL--ERLKQQMPLGADCARYTTLSLLR----RARMHIQKLE 110
LE+RRR + +R E L++Q A AR + R R RM +
Sbjct: 815 QQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 874
Query: 111 ---DQEQRARQLKERLRSKQQSLQRQLEQ--LRGLAGAAERERLRADSLDSSGLSSERSD 165
++E+R R+ E R K+ QRQ +Q LR L ++++L L SS ++S+
Sbjct: 875 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 934
Query: 166 S 166
+
Sbjct: 935 T 935
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 41.6 bits (96), Expect = 5e-04
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 16/136 (11%)
Query: 41 IHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLR 100
+ R+K+ Q Q++ R + + ++++ AQ+K Q C TLSL
Sbjct: 889 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 948
Query: 101 RARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLS 160
IQKLE E+R RQL+E R +Q+ L + L+Q +++ + L G
Sbjct: 949 -----IQKLE--EERERQLREEQRRQQRELMKALQQ---------QQQQQQQKLSGWGNV 992
Query: 161 SERSDSDQEELEVDVE 176
S+ S + + LE+ E
Sbjct: 993 SKPSGTTKSLLEIQQE 1008
Score = 35.8 bits (81), Expect = 0.026
Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 8/114 (7%)
Query: 64 ELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERL 123
+LEK + A+L++ ER + +M + LRR + I + + +E+R R+ +E L
Sbjct: 728 QLEKAKAAKLEQ--ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 124 --RSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSD----QEEL 171
R ++++L+RQ EQ L E E + L R + + QEEL
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
Score = 30.8 bits (68), Expect = 0.85
Identities = 45/181 (24%), Positives = 78/181 (43%), Gaps = 20/181 (11%)
Query: 2 EPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKK-----RPPQAPGAQD 56
E L + +L+ + ER+ RE E L + + R+++ R + +
Sbjct: 759 EELRRQQEEILRRQQEEERKRREEEE----LARRKQEEALRRQREQEIALRRQREEEERQ 814
Query: 57 SGRSVHNELEKRRRAQLKRCL--ERLKQQMPLGADCARYTTLSLLR----RARMHIQKLE 110
LE+RRR + +R E L++Q A AR + R R RM +
Sbjct: 815 QQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 874
Query: 111 ---DQEQRARQLKERLRSKQQSLQRQLEQ--LRGLAGAAERERLRADSLDSSGLSSERSD 165
++E+R R+ E R K+ QRQ +Q LR L ++++L L SS ++S+
Sbjct: 875 LRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSN 934
Query: 166 S 166
+
Sbjct: 935 T 935
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/149 (24%), Positives = 73/149 (48%), Gaps = 27/149 (18%)
Query: 6 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL 65
SN + L Q + ++++R+ E L +H+R++R + +
Sbjct: 364 SNSEALKQQQQLQQQQQRDPEAHIKHL--------LHQRQRR-------------IEEQK 402
Query: 66 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS 125
E+RRR + ++ ER ++++ R + LRR Q +QE + +QL+E+ +S
Sbjct: 403 EERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQS 462
Query: 126 KQQSLQRQLEQ----LRGLAGAAERERLR 150
++ LQRQL+Q L+ L ++++L+
Sbjct: 463 ER--LQRQLQQEHAYLKSLQQQQQQQQLQ 489
Score = 30.4 bits (67), Expect = 1.1
Identities = 29/131 (22%), Positives = 64/131 (48%), Gaps = 12/131 (9%)
Query: 68 RRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQ 127
R + + K E LKQQ L R + +++E+Q++ R+++E+ R ++
Sbjct: 357 RLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRRER 416
Query: 128 QSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELL 187
+ QR+L++ + ++ R + + + ER +++E+ E + L ++E L
Sbjct: 417 E--QRKLQE--------KEQQRRLEDMQALRREEERRQAEREQ-EYKRKQLEEQRQSERL 465
Query: 188 RGFVAGQEHSY 198
+ + QEH+Y
Sbjct: 466 QRQLQ-QEHAY 475
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/149 (24%), Positives = 73/149 (48%), Gaps = 27/149 (18%)
Query: 6 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL 65
SN + L Q + ++++R+ E L +H+R++R + +
Sbjct: 364 SNSEALKQQQQLQQQQQRDPEAHIKHL--------LHQRQRR-------------IEEQK 402
Query: 66 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS 125
E+RRR + ++ ER ++++ R + LRR Q +QE + +QL+E+ +S
Sbjct: 403 EERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQS 462
Query: 126 KQQSLQRQLEQ----LRGLAGAAERERLR 150
++ LQRQL+Q L+ L ++++L+
Sbjct: 463 ER--LQRQLQQEHAYLKSLQQQQQQQQLQ 489
Score = 30.4 bits (67), Expect = 1.1
Identities = 29/131 (22%), Positives = 64/131 (48%), Gaps = 12/131 (9%)
Query: 68 RRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQ 127
R + + K E LKQQ L R + +++E+Q++ R+++E+ R ++
Sbjct: 357 RLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRRER 416
Query: 128 QSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELL 187
+ QR+L++ + ++ R + + + ER +++E+ E + L ++E L
Sbjct: 417 E--QRKLQE--------KEQQRRLEDMQALRREEERRQAEREQ-EYKRKQLEEQRQSERL 465
Query: 188 RGFVAGQEHSY 198
+ + QEH+Y
Sbjct: 466 QRQLQ-QEHAY 475
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/149 (24%), Positives = 73/149 (48%), Gaps = 27/149 (18%)
Query: 6 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL 65
SN + L Q + ++++R+ E L +H+R++R + +
Sbjct: 364 SNSEALKQQQQLQQQQQRDPEAHIKHL--------LHQRQRR-------------IEEQK 402
Query: 66 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS 125
E+RRR + ++ ER ++++ R + LRR Q +QE + +QL+E+ +S
Sbjct: 403 EERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQS 462
Query: 126 KQQSLQRQLEQ----LRGLAGAAERERLR 150
++ LQRQL+Q L+ L ++++L+
Sbjct: 463 ER--LQRQLQQEHAYLKSLQQQQQQQQLQ 489
Score = 30.4 bits (67), Expect = 1.1
Identities = 29/131 (22%), Positives = 64/131 (48%), Gaps = 12/131 (9%)
Query: 68 RRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQ 127
R + + K E LKQQ L R + +++E+Q++ R+++E+ R ++
Sbjct: 357 RLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRRER 416
Query: 128 QSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELL 187
+ QR+L++ + ++ R + + + ER +++E+ E + L ++E L
Sbjct: 417 E--QRKLQE--------KEQQRRLEDMQALRREEERRQAEREQ-EYKRKQLEEQRQSERL 465
Query: 188 RGFVAGQEHSY 198
+ + QEH+Y
Sbjct: 466 QRQLQ-QEHAY 475
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/149 (24%), Positives = 73/149 (48%), Gaps = 27/149 (18%)
Query: 6 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL 65
SN + L Q + ++++R+ E L +H+R++R + +
Sbjct: 364 SNSEALKQQQQLQQQQQRDPEAHIKHL--------LHQRQRR-------------IEEQK 402
Query: 66 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS 125
E+RRR + ++ ER ++++ R + LRR Q +QE + +QL+E+ +S
Sbjct: 403 EERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQS 462
Query: 126 KQQSLQRQLEQ----LRGLAGAAERERLR 150
++ LQRQL+Q L+ L ++++L+
Sbjct: 463 ER--LQRQLQQEHAYLKSLQQQQQQQQLQ 489
Score = 30.4 bits (67), Expect = 1.1
Identities = 29/131 (22%), Positives = 64/131 (48%), Gaps = 12/131 (9%)
Query: 68 RRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQ 127
R + + K E LKQQ L R + +++E+Q++ R+++E+ R ++
Sbjct: 357 RLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRRER 416
Query: 128 QSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELL 187
+ QR+L++ + ++ R + + + ER +++E+ E + L ++E L
Sbjct: 417 E--QRKLQE--------KEQQRRLEDMQALRREEERRQAEREQ-EYKRKQLEEQRQSERL 465
Query: 188 RGFVAGQEHSY 198
+ + QEH+Y
Sbjct: 466 QRQLQ-QEHAY 475
>gi|38156705 microphthalmia-associated transcription factor isoform
6 [Homo sapiens]
Length = 495
Score = 40.4 bits (93), Expect = 0.001
Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
Query: 33 CPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADC-A 91
CP P + +A + + HN +E+RRR + ++ L +P D
Sbjct: 256 CPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDM 315
Query: 92 RYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRA 151
R+ ++L+ + +I+KL+ ++QRA++L+ R + + + + L +++ L A L
Sbjct: 316 RWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGL-- 373
Query: 152 DSLDSSGLSS 161
+ S+GL S
Sbjct: 374 SLIPSTGLCS 383
>gi|38156703 microphthalmia-associated transcription factor isoform
2 [Homo sapiens]
Length = 504
Score = 40.4 bits (93), Expect = 0.001
Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
Query: 33 CPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADC-A 91
CP P + +A + + HN +E+RRR + ++ L +P D
Sbjct: 265 CPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDM 324
Query: 92 RYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRA 151
R+ ++L+ + +I+KL+ ++QRA++L+ R + + + + L +++ L A L
Sbjct: 325 RWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGL-- 382
Query: 152 DSLDSSGLSS 161
+ S+GL S
Sbjct: 383 SLIPSTGLCS 392
>gi|38156701 microphthalmia-associated transcription factor isoform
3 [Homo sapiens]
Length = 519
Score = 40.4 bits (93), Expect = 0.001
Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
Query: 33 CPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADC-A 91
CP P + +A + + HN +E+RRR + ++ L +P D
Sbjct: 280 CPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDM 339
Query: 92 RYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRA 151
R+ ++L+ + +I+KL+ ++QRA++L+ R + + + + L +++ L A L
Sbjct: 340 RWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGL-- 397
Query: 152 DSLDSSGLSS 161
+ S+GL S
Sbjct: 398 SLIPSTGLCS 407
>gi|38156699 microphthalmia-associated transcription factor isoform
1 [Homo sapiens]
Length = 520
Score = 40.4 bits (93), Expect = 0.001
Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
Query: 33 CPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADC-A 91
CP P + +A + + HN +E+RRR + ++ L +P D
Sbjct: 281 CPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDM 340
Query: 92 RYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRA 151
R+ ++L+ + +I+KL+ ++QRA++L+ R + + + + L +++ L A L
Sbjct: 341 RWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGL-- 398
Query: 152 DSLDSSGLSS 161
+ S+GL S
Sbjct: 399 SLIPSTGLCS 408
>gi|38156697 microphthalmia-associated transcription factor isoform
5 [Homo sapiens]
Length = 413
Score = 40.4 bits (93), Expect = 0.001
Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 3/130 (2%)
Query: 33 CPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADC-A 91
CP P + +A + + HN +E+RRR + ++ L +P D
Sbjct: 174 CPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDM 233
Query: 92 RYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRA 151
R+ ++L+ + +I+KL+ ++QRA++L+ R + + + + L +++ L A L
Sbjct: 234 RWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGL-- 291
Query: 152 DSLDSSGLSS 161
+ S+GL S
Sbjct: 292 SLIPSTGLCS 301
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 17/103 (16%)
Query: 48 PPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQ 107
PP P + + N L K LE + +Q L A+ LSLL R + +
Sbjct: 152 PPAGPSKVEQLQDETNHLRKE--------LESVGRQ--LQAEVENNQMLSLLNRRQE--E 199
Query: 108 KLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLR 150
+L +QE+R R+ +ERLR +++ L Q E+LR + ERLR
Sbjct: 200 RLREQEERLREQEERLREQEERLCEQEERLR-----EQEERLR 237
Score = 36.2 bits (82), Expect = 0.020
Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 21/114 (18%)
Query: 65 LEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLR 124
L +R+ +L+ ERL++Q R R ++L +QE+R R+ +ERLR
Sbjct: 193 LNRRQEERLREQEERLREQE---------------ERLREQEERLCEQEERLREQEERLR 237
Query: 125 SKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESL 178
+++ L Q E+LR E E + + ER +E L E L
Sbjct: 238 EQEERLCEQEERLR------EHEERLCEQEERLCEQEERLREQEERLHEQEERL 285
Score = 33.9 bits (76), Expect = 0.10
Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 101 RARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAG--AAERERLRADSLDSSG 158
R R ++L +QE+R + +ERLR +++ L Q E+LR + ERLR
Sbjct: 270 RLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLRE---QEER 326
Query: 159 LSSERSDSDQEELEVDVESLV 179
L + QE L +VE L+
Sbjct: 327 LCEQEKLPGQERLLEEVEKLL 347
Score = 30.4 bits (67), Expect = 1.1
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 107 QKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDS 166
++L +QE+R R+ +ERL +++ L Q E+LR E+E + + ER
Sbjct: 262 ERLCEQEERLREQEERLHEQEERLCEQEERLR------EQEERLCEQEERLREQEERLCE 315
Query: 167 DQEELEVDVESL 178
+E L E L
Sbjct: 316 QEERLREQEERL 327
>gi|195972857 Rho/Rac guanine nucleotide exchange factor 18 isoform
b [Homo sapiens]
Length = 1173
Score = 39.7 bits (91), Expect = 0.002
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 64 ELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERL 123
E ++ RA L++ +L+ + ++ L R +L+++E ARQL+ERL
Sbjct: 859 EKQREERAALEKLQSQLRHEQQRWERERQWQHQELERAGA----RLQEREGEARQLRERL 914
Query: 124 RSKQQSLQRQ-------LEQLRGLAGAAERERLRADSL 154
++ L+RQ LE+LR A ERER R + L
Sbjct: 915 EQERAELERQRQAYQHDLERLREAQRAVERERERLELL 952
>gi|41327769 Rho/Rac guanine nucleotide exchange factor 18 isoform a
[Homo sapiens]
Length = 1015
Score = 39.7 bits (91), Expect = 0.002
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 11/98 (11%)
Query: 64 ELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERL 123
E ++ RA L++ +L+ + ++ L R +L+++E ARQL+ERL
Sbjct: 701 EKQREERAALEKLQSQLRHEQQRWERERQWQHQELERAGA----RLQEREGEARQLRERL 756
Query: 124 RSKQQSLQRQ-------LEQLRGLAGAAERERLRADSL 154
++ L+RQ LE+LR A ERER R + L
Sbjct: 757 EQERAELERQRQAYQHDLERLREAQRAVERERERLELL 794
>gi|195947367 golgi autoantigen, golgin subfamily a, 8B [Homo
sapiens]
Length = 603
Score = 39.3 bits (90), Expect = 0.002
Identities = 41/144 (28%), Positives = 72/144 (50%), Gaps = 21/144 (14%)
Query: 48 PPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQ 107
PP AP +V +E+E + L++ LER+ + L A +SLL R + +
Sbjct: 288 PPDAP-------AVSSEVELQ---DLRKELERVAGE--LQAQVENNQCISLLNRGQK--E 333
Query: 108 KLEDQEQRARQLKERLRSKQQSLQR------QLEQLR-GLAGAAERERLRADSLDSSGLS 160
+L +QE+R ++ +ERLR +++ LQ+ LE+L+ A + E+ + + G
Sbjct: 334 RLREQEERLQEQQERLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKELQEKLGQV 393
Query: 161 SERSDSDQEELEVDVESLVFGGEA 184
E S ++E E V + GGE+
Sbjct: 394 METLTSAEKEPEAAVPASGTGGES 417
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,180,163
Number of Sequences: 37866
Number of extensions: 381828
Number of successful extensions: 5620
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 223
Number of HSP's successfully gapped in prelim test: 431
Number of HSP's that attempted gapping in prelim test: 3498
Number of HSP's gapped (non-prelim): 1908
length of query: 206
length of database: 18,247,518
effective HSP length: 97
effective length of query: 109
effective length of database: 14,574,516
effective search space: 1588622244
effective search space used: 1588622244
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.