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Search of human proteins with 6912660
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912660 sirtuin 3 isoform a [Homo sapiens]
(399 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912660 sirtuin 3 isoform a [Homo sapiens] 811 0.0
gi|63054862 sirtuin 3 isoform b [Homo sapiens] 528 e-150
gi|13775600 sirtuin 2 isoform 1 [Homo sapiens] 288 5e-78
gi|13775602 sirtuin 2 isoform 2 [Homo sapiens] 286 2e-77
gi|7657575 sirtuin 1 isoform a [Homo sapiens] 194 9e-50
gi|215982798 sirtuin 1 isoform b [Homo sapiens] 155 6e-38
gi|6912662 sirtuin 4 [Homo sapiens] 85 1e-16
gi|13787215 sirtuin 5 isoform 2 [Homo sapiens] 84 2e-16
gi|6912664 sirtuin 5 isoform 1 [Homo sapiens] 84 2e-16
gi|7706710 sirtuin 6 [Homo sapiens] 84 3e-16
gi|7706712 sirtuin 7 [Homo sapiens] 66 5e-11
gi|239750914 PREDICTED: hypothetical protein XP_002347614 [Homo ... 33 0.45
gi|239745312 PREDICTED: hypothetical protein XP_002343435 [Homo ... 33 0.45
gi|225690502 junctophilin 4 [Homo sapiens] 33 0.45
gi|225690500 junctophilin 4 [Homo sapiens] 33 0.45
gi|122937207 coiled-coil domain containing 61 [Homo sapiens] 32 1.0
gi|169213235 PREDICTED: hypothetical protein [Homo sapiens] 31 1.7
gi|169212744 PREDICTED: hypothetical protein [Homo sapiens] 31 1.7
gi|239744552 PREDICTED: hypothetical protein [Homo sapiens] 31 1.7
gi|169202233 PREDICTED: hypothetical protein [Homo sapiens] 31 1.7
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 31 2.3
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens] 31 2.3
gi|11056048 doublesex and mab-3 related transcription factor 3 [... 31 2.3
gi|38194229 kelch-like 17 [Homo sapiens] 31 2.3
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens] 30 2.9
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 30 2.9
gi|4503615 even-skipped homeobox 1 [Homo sapiens] 30 2.9
gi|119372312 galactosidase, beta 1 isoform b [Homo sapiens] 30 3.8
gi|119372308 galactosidase, beta 1 isoform a preproprotein [Homo... 30 3.8
gi|169204952 PREDICTED: hypothetical protein [Homo sapiens] 30 3.8
>gi|6912660 sirtuin 3 isoform a [Homo sapiens]
Length = 399
Score = 811 bits (2095), Expect = 0.0
Identities = 399/399 (100%), Positives = 399/399 (100%)
Query: 1 MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEP 60
MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEP
Sbjct: 1 MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEP 60
Query: 61 LDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDK 120
LDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDK
Sbjct: 61 LDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDK 120
Query: 121 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIF 180
GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIF
Sbjct: 121 GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIF 180
Query: 181 ELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIP 240
ELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIP
Sbjct: 181 ELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIP 240
Query: 241 ASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ 300
ASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ
Sbjct: 241 ASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ 300
Query: 301 RFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDV 360
RFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDV
Sbjct: 301 RFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDV 360
Query: 361 AQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK 399
AQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK
Sbjct: 361 AQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK 399
>gi|63054862 sirtuin 3 isoform b [Homo sapiens]
Length = 257
Score = 528 bits (1359), Expect = e-150
Identities = 257/257 (100%), Positives = 257/257 (100%)
Query: 143 MVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPG 202
MVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPG
Sbjct: 1 MVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPG 60
Query: 203 NYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRP 262
NYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRP
Sbjct: 61 NYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRP 120
Query: 263 FPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSL 322
FPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSL
Sbjct: 121 FPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSL 180
Query: 323 EVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEE 382
EVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEE
Sbjct: 181 EVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEE 240
Query: 383 MRDLVQRETGKLDGPDK 399
MRDLVQRETGKLDGPDK
Sbjct: 241 MRDLVQRETGKLDGPDK 257
>gi|13775600 sirtuin 2 isoform 1 [Homo sapiens]
Length = 389
Score = 288 bits (738), Expect = 5e-78
Identities = 162/356 (45%), Positives = 219/356 (61%), Gaps = 29/356 (8%)
Query: 62 DPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDK- 120
DP+ PL+ +A + Q + S GG + F S S GS +
Sbjct: 5 DPSHPLET-------QAGKVQEAQDSDSDSEGGAAGGEADMDFLRNLFSQTLSLGSQKER 57
Query: 121 --GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEA 178
+L+L+ VA +++ C+RV+ +VGAGIST +GIPDFRSP +GLY NL++Y LPYPEA
Sbjct: 58 LLDELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEA 117
Query: 179 IFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSG 238
IFE+ +F +P+PFF LAKELYPG +KP + HYF+RLL DKGLLLR YTQNID LER++G
Sbjct: 118 IFEISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAG 177
Query: 239 IPASKLVEAHGTFASATC--TVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGE 296
+ LVEAHGTF ++ C C+ +P ++ + ++ P+C C +VKPDIVFFGE
Sbjct: 178 LEQEDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGE 237
Query: 297 PLPQRFLLHV-VDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRD--------- 346
LP RF + DF DLLL++GTSL+V+PFASL S PRLLIN++
Sbjct: 238 SLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFL 297
Query: 347 -----LVGPLAWHPRS--RDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLD 395
L G + + + RDVA LG+ G +L ELLGW +E+ DLV+RE +D
Sbjct: 298 GMIMGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASID 353
>gi|13775602 sirtuin 2 isoform 2 [Homo sapiens]
Length = 352
Score = 286 bits (732), Expect = 2e-77
Identities = 148/293 (50%), Positives = 198/293 (67%), Gaps = 19/293 (6%)
Query: 122 KLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFE 181
+L+L+ VA +++ C+RV+ +VGAGIST +GIPDFRSP +GLY NL++Y LPYPEAIFE
Sbjct: 24 ELTLEGVARYMQSERCRRVICLVGAGISTSAGIPDFRSPSTGLYDNLEKYHLPYPEAIFE 83
Query: 182 LPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPA 241
+ +F +P+PFF LAKELYPG +KP + HYF+RLL DKGLLLR YTQNID LER++G+
Sbjct: 84 ISYFKKHPEPFFALAKELYPGQFKPTICHYFMRLLKDKGLLLRCYTQNIDTLERIAGLEQ 143
Query: 242 SKLVEAHGTFASATC--TVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLP 299
LVEAHGTF ++ C C+ +P ++ + ++ P+C C +VKPDIVFFGE LP
Sbjct: 144 EDLVEAHGTFYTSHCVSASCRHEYPLSWMKEKIFSEVTPKCEDCQSLVKPDIVFFGESLP 203
Query: 300 QRFLLHV-VDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRD------------ 346
RF + DF DLLL++GTSL+V+PFASL S PRLLIN++
Sbjct: 204 ARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTPRLLINKEKAGQSDPFLGMI 263
Query: 347 --LVGPLAWHPRS--RDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLD 395
L G + + + RDVA LG+ G +L ELLGW +E+ DLV+RE +D
Sbjct: 264 MGLGGGMDFDSKKAYRDVAWLGECDQGCLALAELLGWKKELEDLVRREHASID 316
>gi|7657575 sirtuin 1 isoform a [Homo sapiens]
Length = 747
Score = 194 bits (494), Expect = 9e-50
Identities = 106/263 (40%), Positives = 167/263 (63%), Gaps = 18/263 (6%)
Query: 124 SLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQY--DLPYPEAIFE 181
+++D +L++ C++++V+ GAG+S GIPDFRS G+Y+ L DLP P+A+F+
Sbjct: 242 TIEDAVKLLQE--CKKIIVLTGAGVSVSCGIPDFRSR-DGIYARLAVDFPDLPDPQAMFD 298
Query: 182 LPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPA 241
+ +F +P+PFF AKE+YPG ++P++ H F+ L +G LLR YTQNID LE+V+GI
Sbjct: 299 IEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGI-- 356
Query: 242 SKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVC-----TGVVKPDIVFFGE 296
++++ HG+FA+A+C +C+ E +R D+ VPRCP C ++KP+IVFFGE
Sbjct: 357 QRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGE 416
Query: 297 PLPQRFLLHV-VDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHP 355
LP++F + D DLL+++G+SL+V P A + ++ VP++LINR+ + L +
Sbjct: 417 NLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHF-- 474
Query: 356 RSRDVAQLGDVVHGVESLVELLG 378
DV LGD + L LG
Sbjct: 475 ---DVELLGDCDVIINELCHRLG 494
>gi|215982798 sirtuin 1 isoform b [Homo sapiens]
Length = 452
Score = 155 bits (392), Expect = 6e-38
Identities = 83/206 (40%), Positives = 129/206 (62%), Gaps = 13/206 (6%)
Query: 179 IFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSG 238
+F++ +F +P+PFF AKE+YPG ++P++ H F+ L +G LLR YTQNID LE+V+G
Sbjct: 1 MFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAG 60
Query: 239 IPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVC-----TGVVKPDIVF 293
I ++++ HG+FA+A+C +C+ E +R D+ VPRCP C ++KP+IVF
Sbjct: 61 I--QRIIQCHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVF 118
Query: 294 FGEPLPQRFLLHV-VDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLA 352
FGE LP++F + D DLL+++G+SL+V P A + ++ VP++LINR+ + L
Sbjct: 119 FGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLH 178
Query: 353 WHPRSRDVAQLGDVVHGVESLVELLG 378
+ DV LGD + L LG
Sbjct: 179 F-----DVELLGDCDVIINELCHRLG 199
>gi|6912662 sirtuin 4 [Homo sapiens]
Length = 314
Score = 85.1 bits (209), Expect = 1e-16
Identities = 76/255 (29%), Positives = 114/255 (44%), Gaps = 40/255 (15%)
Query: 138 QRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAK 197
+R++VM GAGIST SGIPD+RS GLY+ + + + + + P F
Sbjct: 55 KRLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQHGDFVRSAPIRQRYWARNFVGWP 114
Query: 198 ELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCT 257
+ +++PN H+ L G L L TQN+D L +G + +L E HG C
Sbjct: 115 QF--SSHQPNPAHWALSTWEKLGKLYWLVTQNVDALHTKAG--SRRLTELHGCMDRVLCL 170
Query: 258 VC---------QRPF---------------PGEDI---RADVMADRVPRCPVCTGVVKPD 290
C Q F P D+ V + +VP C C G +KPD
Sbjct: 171 DCGEQTPRGVLQERFQVLNPTWSAEAHGLAPDGDVFLSEEQVRSFQVPTCVQCGGHLKPD 230
Query: 291 IVFFGEPL-PQRFLLHVVDFPMADLLLILGTSLEV-EPFASLTEAVRSSVPRLLINRDLV 348
+VFFG+ + P + AD LL++G+SL+V + + A +P ++N +
Sbjct: 231 VVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQVYSGYRFILTAWEKKLPIAILN---I 287
Query: 349 GPLAWHPRSRDVAQL 363
GP RS D+A L
Sbjct: 288 GP----TRSDDLACL 298
>gi|13787215 sirtuin 5 isoform 2 [Homo sapiens]
Length = 299
Score = 84.3 bits (207), Expect = 2e-16
Identities = 73/226 (32%), Positives = 105/226 (46%), Gaps = 41/226 (18%)
Query: 138 QRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPK---PFFT 194
+ +V++ GAG+S SG+P FR G G + Q DL P A F HNP F+
Sbjct: 51 KHIVIISGAGVSAESGVPTFRGAG-GYWRKWQAQDLATPLA------FAHNPSRVWEFYH 103
Query: 195 LAKELYPGNYKPNVTHYFL----RLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGT 250
+E+ G+ +PN H + L +G + + TQNID L R +G L+E HG+
Sbjct: 104 YRREVM-GSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAG--TKNLLEIHGS 160
Query: 251 FASATCTVC------------------QRPFPGEDIRADVMADRVPRCPV--CTGVVKPD 290
CT C P PG A + +++PRC C G+++P
Sbjct: 161 LFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQ-DASIPVEKLPRCEEAGCGGLLRPH 219
Query: 291 IVFFGEPLPQRFLLHVVDFPMA--DLLLILGTSLEVEPFASLTEAV 334
+V+FGE L +L VD +A DL L++GTS V P A V
Sbjct: 220 VVWFGENLDPA-ILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQV 264
>gi|6912664 sirtuin 5 isoform 1 [Homo sapiens]
Length = 310
Score = 84.3 bits (207), Expect = 2e-16
Identities = 73/226 (32%), Positives = 105/226 (46%), Gaps = 41/226 (18%)
Query: 138 QRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPK---PFFT 194
+ +V++ GAG+S SG+P FR G G + Q DL P A F HNP F+
Sbjct: 51 KHIVIISGAGVSAESGVPTFRGAG-GYWRKWQAQDLATPLA------FAHNPSRVWEFYH 103
Query: 195 LAKELYPGNYKPNVTHYFL----RLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGT 250
+E+ G+ +PN H + L +G + + TQNID L R +G L+E HG+
Sbjct: 104 YRREVM-GSKEPNAGHRAIAECETRLGKQGRRVVVITQNIDELHRKAG--TKNLLEIHGS 160
Query: 251 FASATCTVC------------------QRPFPGEDIRADVMADRVPRCPV--CTGVVKPD 290
CT C P PG A + +++PRC C G+++P
Sbjct: 161 LFKTRCTSCGVVAENYKSPICPALSGKGAPEPGTQ-DASIPVEKLPRCEEAGCGGLLRPH 219
Query: 291 IVFFGEPLPQRFLLHVVDFPMA--DLLLILGTSLEVEPFASLTEAV 334
+V+FGE L +L VD +A DL L++GTS V P A V
Sbjct: 220 VVWFGENLDPA-ILEEVDRELAHCDLCLVVGTSSVVYPAAMFAPQV 264
>gi|7706710 sirtuin 6 [Homo sapiens]
Length = 355
Score = 83.6 bits (205), Expect = 3e-16
Identities = 89/300 (29%), Positives = 127/300 (42%), Gaps = 53/300 (17%)
Query: 101 SISFSVGASSVVGSGGSSDKGKLSLQDVA-----------ELIR-ARACQRVVVMVGAGI 148
S++++ G S +DKGK L ++ EL R VV GAGI
Sbjct: 2 SVNYAAGLSPY------ADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGI 55
Query: 149 STPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNV 208
ST SGIPDFR P G+++ ++ P + FE + +P
Sbjct: 56 STASGIPDFRGP-HGVWTMEERGLAPKFDTTFE---------------------SARPTQ 93
Query: 209 THYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDI 268
TH L L GLL L +QN+DGL SG P KL E HG C C+ + + +
Sbjct: 94 THMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTV 153
Query: 269 RADVMADRVPR-CPV--------CTGVVKPDIVFFGEPLPQRFLLHVVDFPM-ADLLLIL 318
+ R C V C G ++ I+ + + LP R L + ADL + L
Sbjct: 154 VGTMGLKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITL 213
Query: 319 GTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLG 378
GTSL++ P +L A + RL+I + P H R D+ G V + L+E LG
Sbjct: 214 GTSLQIRPSGNLPLATKRRGGRLVIVN--LQPTK-HDRHADLRIHGYVDEVMTRLMEHLG 270
>gi|7706712 sirtuin 7 [Homo sapiens]
Length = 400
Score = 66.2 bits (160), Expect = 5e-11
Identities = 64/211 (30%), Positives = 93/211 (44%), Gaps = 40/211 (18%)
Query: 128 VAELIRA-RACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFF 186
V EL A R + +VV GAGIST + IPD+R P +G+++ LQ
Sbjct: 89 VRELASAVRNAKYLVVYTGAGISTAASIPDYRGP-NGVWTLLQ----------------- 130
Query: 187 HNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVE 246
K A +L +P +TH + LH++ L+ + +QN DGL SG+P + + E
Sbjct: 131 ---KGRSVSAADL--SEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISE 185
Query: 247 AHGTFASATCTVCQRPFPG-EDIRADVMADRVP--------RCPVCTGVVKPDIVFFGE- 296
HG CT C P E +R + +R C C ++ IV FGE
Sbjct: 186 LHGNMYIEVCTSC---VPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGER 242
Query: 297 ---PLPQRFLLHVVDFPMADLLLILGTSLEV 324
P + AD +L LG+SL+V
Sbjct: 243 GTLGQPLNWEAATEAASRADTILCLGSSLKV 273
>gi|239750914 PREDICTED: hypothetical protein XP_002347614 [Homo
sapiens]
Length = 492
Score = 33.1 bits (74), Expect = 0.45
Identities = 29/97 (29%), Positives = 35/97 (36%), Gaps = 14/97 (14%)
Query: 21 RVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFR 80
R E GGG G R DV+AG R EPL R RP P P
Sbjct: 358 RGEGGGG-------------GSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPC- 403
Query: 81 RQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGS 117
P A + + GGR + S G + G G +
Sbjct: 404 LPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAA 440
>gi|239745312 PREDICTED: hypothetical protein XP_002343435 [Homo
sapiens]
Length = 492
Score = 33.1 bits (74), Expect = 0.45
Identities = 29/97 (29%), Positives = 35/97 (36%), Gaps = 14/97 (14%)
Query: 21 RVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFR 80
R E GGG G R DV+AG R EPL R RP P P
Sbjct: 358 RGEGGGG-------------GSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPLPC- 403
Query: 81 RQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGS 117
P A + + GGR + S G + G G +
Sbjct: 404 LPPAAVCHALAGAGAPGGRLELGLSPGTRLIRGGGAA 440
>gi|225690502 junctophilin 4 [Homo sapiens]
Length = 628
Score = 33.1 bits (74), Expect = 0.45
Identities = 28/71 (39%), Positives = 29/71 (40%), Gaps = 4/71 (5%)
Query: 4 WGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDP 63
WG A A L G E + G GP G L LGG D S LR G EPL P
Sbjct: 499 WGGAGAQAEELAGYEAE--DEAGMQGPGPRDGSPL-LGGCSDSSGSLREEEGEDEEPLPP 555
Query: 64 AR-PLQRPPRP 73
R P P P
Sbjct: 556 LRAPAGTEPEP 566
>gi|225690500 junctophilin 4 [Homo sapiens]
Length = 628
Score = 33.1 bits (74), Expect = 0.45
Identities = 28/71 (39%), Positives = 29/71 (40%), Gaps = 4/71 (5%)
Query: 4 WGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDP 63
WG A A L G E + G GP G L LGG D S LR G EPL P
Sbjct: 499 WGGAGAQAEELAGYEAE--DEAGMQGPGPRDGSPL-LGGCSDSSGSLREEEGEDEEPLPP 555
Query: 64 AR-PLQRPPRP 73
R P P P
Sbjct: 556 LRAPAGTEPEP 566
>gi|122937207 coiled-coil domain containing 61 [Homo sapiens]
Length = 531
Score = 32.0 bits (71), Expect = 1.0
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 9/74 (12%)
Query: 51 RGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASS 110
RG G+RG RP + P P RA R P A F + + +R I +
Sbjct: 338 RGGRGSRGR----GRPARPSPSPTGGRALRFDPTA-----FVKAKERKQREIQMKQQQRN 388
Query: 111 VVGSGGSSDKGKLS 124
+GSGGS D +S
Sbjct: 389 RLGSGGSGDGPSVS 402
>gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]
Length = 308
Score = 31.2 bits (69), Expect = 1.7
Identities = 44/152 (28%), Positives = 53/152 (34%), Gaps = 18/152 (11%)
Query: 10 AALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQR 69
AAL + GR E AG G +L R VSAG GS R PA P
Sbjct: 24 AALAISGRADEEGAAGAG--------SKLWRRPRGAVSAGAPGSPLYRVSAPPPAPP--P 73
Query: 70 PPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVA 129
PP P P R P F S GRR +S G GS+ + + S ++
Sbjct: 74 PPPPGGPSRSERPRAGLRPGAFVSPGPLGRR--------ASCSGRAGSAGRLRCSAAALS 125
Query: 130 ELIRARACQRVVVMVGAGISTPSGIPDFRSPG 161
R + V S P SPG
Sbjct: 126 AAQRGGPARAQVPPALRTFSPGPASPPRASPG 157
>gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]
Length = 308
Score = 31.2 bits (69), Expect = 1.7
Identities = 44/152 (28%), Positives = 53/152 (34%), Gaps = 18/152 (11%)
Query: 10 AALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQR 69
AAL + GR E AG G +L R VSAG GS R PA P
Sbjct: 24 AALAISGRADEEGAAGAG--------SKLWRRPRGAVSAGAPGSPLYRVSAPPPAPP--P 73
Query: 70 PPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVA 129
PP P P R P F S GRR +S G GS+ + + S ++
Sbjct: 74 PPPPGGPSRSERPRAGLRPGAFVSPGPLGRR--------ASCSGRAGSAGRLRCSAAALS 125
Query: 130 ELIRARACQRVVVMVGAGISTPSGIPDFRSPG 161
R + V S P SPG
Sbjct: 126 AAQRGGPARAQVPPALRTFSPGPASPPRASPG 157
>gi|239744552 PREDICTED: hypothetical protein [Homo sapiens]
Length = 221
Score = 31.2 bits (69), Expect = 1.7
Identities = 33/103 (32%), Positives = 39/103 (37%), Gaps = 11/103 (10%)
Query: 4 WGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGG--RDDVSAGLRGSHGARGEPL 61
WG L G + + G G +A R GG R+ + G RG ARG
Sbjct: 25 WGGEEVQGLARAGLATGKGQRPPGPGRVRAAQARARRGGGARERPAEGARGPRAARGGAR 84
Query: 62 DPARPLQRPPRPEVPRAFRR-----QPRAAAPSFFFSSIKGGR 99
P P P P A RR +P A APS SS GR
Sbjct: 85 AAPMPSSAPRGPTEP-ALRRPSSAERPLAQAPS---SSASVGR 123
>gi|169202233 PREDICTED: hypothetical protein [Homo sapiens]
Length = 381
Score = 31.2 bits (69), Expect = 1.7
Identities = 20/34 (58%), Positives = 22/34 (64%), Gaps = 4/34 (11%)
Query: 56 ARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPS 89
+RGEP PA P + PPRP P A RR P A APS
Sbjct: 303 SRGEPR-PAEP-RAPPRP--PPAARRPPPATAPS 332
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 30.8 bits (68), Expect = 2.3
Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 49 GLRGSHGARGEP--LDPARPLQRPPRPEVPRAFRRQPRAAAPS 89
G RG G +GEP ++P ++ PP PE P P P+
Sbjct: 447 GPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPT 489
>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
Length = 669
Score = 30.8 bits (68), Expect = 2.3
Identities = 21/46 (45%), Positives = 26/46 (56%), Gaps = 8/46 (17%)
Query: 49 GLRGSHGARGEPLDPARPLQRPP-RPEVP------RAFRRQPRAAA 87
GLR SH R PL PA L PP +P +P ++FRR P AA+
Sbjct: 432 GLRPSHPPRRRPLPPASSLGHPPAKPPLPPGPVDMQSFRR-PSAAS 476
>gi|11056048 doublesex and mab-3 related transcription factor 3
[Homo sapiens]
Length = 472
Score = 30.8 bits (68), Expect = 2.3
Identities = 46/206 (22%), Positives = 80/206 (38%), Gaps = 27/206 (13%)
Query: 66 PLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRS-ISFSVGASSVVGSGGSSDKGKL- 123
P +P +P+ PR AAA + G ++ ++ +G G S+D ++
Sbjct: 111 PASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVF 170
Query: 124 --------SLQDVAELIRARAC----QRVVVMV---GAGISTPSGIPDFRSPGSGLYSNL 168
S DVA +++ C +V V G + G P+ R ++
Sbjct: 171 SDKDTDQRSSPDVA---KSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQ 227
Query: 169 QQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLR-----LLHDKGLLL 223
+ P LPF +P + K+++P N KP V L+ L+ +LL
Sbjct: 228 NHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFP-NQKPTVLELILKGCGGDLVSAVEVLL 286
Query: 224 RLYTQNIDGLERVSGIPASKLVEAHG 249
++ G ER S P S + ++G
Sbjct: 287 S-SRSSVTGAERTSAEPESLALPSNG 311
>gi|38194229 kelch-like 17 [Homo sapiens]
Length = 642
Score = 30.8 bits (68), Expect = 2.3
Identities = 17/36 (47%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
Query: 54 HGARGE-PLDPARPLQRPPRPEVPRAFRRQPRAAAP 88
HG+ G P P P +PP PE R RQ R AAP
Sbjct: 17 HGSPGPGPEAPPPPPPQPPAPEAERTRPRQARPAAP 52
>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
Length = 496
Score = 30.4 bits (67), Expect = 2.9
Identities = 43/126 (34%), Positives = 49/126 (38%), Gaps = 24/126 (19%)
Query: 7 RAAAALRLW-GRVV-ERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPA 64
R+ RLW RVV +R E G G G GG +D GS G+R EP A
Sbjct: 6 RSGLVRRLWRSRVVPDREEGGSGGGG----------GGDED------GSLGSRAEPAPRA 49
Query: 65 RPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLS 124
R R EV R+PR A G RR S G+G S S
Sbjct: 50 REGGGCGRSEVRPVAPRRPRDAVGQRGAQG-AGRRRRAGGPPRPMSEPGAGAGS-----S 103
Query: 125 LQDVAE 130
L DVAE
Sbjct: 104 LLDVAE 109
>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
Length = 1604
Score = 30.4 bits (67), Expect = 2.9
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 7/68 (10%)
Query: 49 GLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGA 108
GL G G +GEP DP P + P + + + +P + SS+ G + +S S GA
Sbjct: 522 GLPGKPGPKGEPGDPV-PARGDPGIQGIKGEKGEPCLSC-----SSVVGAQHLVS-STGA 574
Query: 109 SSVVGSGG 116
S VGS G
Sbjct: 575 SGDVGSPG 582
>gi|4503615 even-skipped homeobox 1 [Homo sapiens]
Length = 407
Score = 30.4 bits (67), Expect = 2.9
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 2/60 (3%)
Query: 40 LGGRDDVSAGLRGSHGARGEPLDPARPLQRP-PRPEVPRAFRRQPRAAAPSFFFSSIKGG 98
LG SA G+ PLD R L +P PRPE+ AFR P P+ + GG
Sbjct: 287 LGAASAASAAASPFSGSL-RPLDTFRVLSQPYPRPELLCAFRHPPLYPGPAHGLGASAGG 345
>gi|119372312 galactosidase, beta 1 isoform b [Homo sapiens]
Length = 647
Score = 30.0 bits (66), Expect = 3.8
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 13/47 (27%)
Query: 182 LPFFFHNPKPFFTLAKELYPGNYKPNVTH---YFLRLLHDKGLLLRL 225
+P+ FH P +PG Y+ + H YFLRL H+ GLL+ L
Sbjct: 54 VPWNFHEP----------WPGQYQFSEDHDVEYFLRLAHELGLLVIL 90
>gi|119372308 galactosidase, beta 1 isoform a preproprotein [Homo
sapiens]
Length = 677
Score = 30.0 bits (66), Expect = 3.8
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 13/47 (27%)
Query: 182 LPFFFHNPKPFFTLAKELYPGNYKPNVTH---YFLRLLHDKGLLLRL 225
+P+ FH P +PG Y+ + H YFLRL H+ GLL+ L
Sbjct: 84 VPWNFHEP----------WPGQYQFSEDHDVEYFLRLAHELGLLVIL 120
>gi|169204952 PREDICTED: hypothetical protein [Homo sapiens]
Length = 88
Score = 30.0 bits (66), Expect = 3.8
Identities = 17/43 (39%), Positives = 19/43 (44%)
Query: 42 GRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPR 84
GR G H +R L P+ PL PP P R RR PR
Sbjct: 32 GRGHRRLGPGAQHCSRTGGLKPSPPLPPPPPPPPDRGIRRFPR 74
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.141 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,912,979
Number of Sequences: 37866
Number of extensions: 872352
Number of successful extensions: 3255
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 3191
Number of HSP's gapped (non-prelim): 97
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.