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Search of human proteins with 6912630
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912630 interferon-induced protein with tetratricopeptide
repeats 5 [Homo sapiens]
(482 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912630 interferon-induced protein with tetratricopeptide rep... 971 0.0
gi|116534937 interferon-induced protein with tetratricopeptide r... 538 e-153
gi|58330892 interferon-induced protein with tetratricopeptide re... 520 e-147
gi|153082755 interferon-induced protein with tetratricopeptide r... 403 e-112
gi|31542980 interferon-induced protein with tetratricopeptide re... 377 e-104
gi|72534658 interferon-induced protein with tetratricopeptide re... 377 e-104
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 54 3e-07
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 54 3e-07
gi|83415184 transmembrane and tetratricopeptide repeat containin... 53 7e-07
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 45 2e-04
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 43 7e-04
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ... 41 0.002
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ... 41 0.002
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 40 0.006
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 40 0.006
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 38 0.018
gi|189011544 ubiquitously transcribed tetratricopeptide repeat, ... 35 0.15
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 35 0.20
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 34 0.26
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 34 0.26
gi|239741018 PREDICTED: hypothetical protein XP_002342056 [Homo ... 33 0.44
gi|4557269 adenylosuccinate lyase isoform a [Homo sapiens] 33 0.58
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 33 0.58
gi|22749211 transmembrane and tetratricopeptide repeat containin... 33 0.58
gi|144446030 lymphocyte antigen 75 [Homo sapiens] 33 0.58
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 32 0.98
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 32 0.98
gi|52630440 FK506-binding protein 8 [Homo sapiens] 32 1.3
gi|28603842 tetratricopeptide repeat domain 9C [Homo sapiens] 32 1.3
gi|118766328 transmembrane and tetratricopeptide repeat containi... 32 1.3
>gi|6912630 interferon-induced protein with tetratricopeptide
repeats 5 [Homo sapiens]
Length = 482
Score = 971 bits (2510), Expect = 0.0
Identities = 482/482 (100%), Positives = 482/482 (100%)
Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60
MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV
Sbjct: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60
Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120
KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI
Sbjct: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120
Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180
GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY
Sbjct: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180
Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240
AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE
Sbjct: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240
Query: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300
ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI
Sbjct: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300
Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360
KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI
Sbjct: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360
Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420
FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL
Sbjct: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420
Query: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 480
KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL
Sbjct: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 480
Query: 481 SI 482
SI
Sbjct: 481 SI 482
>gi|116534937 interferon-induced protein with tetratricopeptide
repeats 1 isoform 2 [Homo sapiens]
Length = 478
Score = 538 bits (1385), Expect = e-153
Identities = 266/464 (57%), Positives = 351/464 (75%), Gaps = 3/464 (0%)
Query: 9 LKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNK 68
+K L +L CHFTW L +D ++ ++E+ + Q+EFL TK + ++NLLAYVKHLKGQN+
Sbjct: 10 VKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNE 69
Query: 69 DALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLS 128
+AL+ L++AE ++Q+EH ++ VRSLVTWGN+AW+YYHM +L EAQ Y K+ N+CKKLS
Sbjct: 70 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 129
Query: 129 SPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLD 188
+P Y++ECPE DCE+GWALLK GGK Y++AKA FEK LEV+P+NPE + GYAI+ YRLD
Sbjct: 130 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 189
Query: 189 DSD-REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISS 247
+ K FSL PLR+AV LNPDN YIKV LALKLQD EAEGEKYIEE L +SS
Sbjct: 190 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 249
Query: 248 QPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNR 307
Q YV RYAAKFYRRK S +KALELLKKAL+ TPTS LHHQ+GLCY+AQMIQIK+AT +
Sbjct: 250 QTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQ 309
Query: 308 PKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367
P+G+++ K+D++I SAIFHF++A+E+ F A+ DLA MY E G + AE+ F+K L +
Sbjct: 310 PRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 369
Query: 368 ENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKR 427
+ + ++ IH+HYGRFQEF +KS+ AI HYL+A+K++ S R K ++LKKL ++
Sbjct: 370 KPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRK 429
Query: 428 LCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKI--DPENA 469
L ALD++SLS LGFVYKLEG +A EYYE+A ++ D EN+
Sbjct: 430 LRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473
>gi|58330892 interferon-induced protein with tetratricopeptide
repeats 1-like [Homo sapiens]
Length = 474
Score = 520 bits (1339), Expect = e-147
Identities = 258/453 (56%), Positives = 337/453 (74%), Gaps = 1/453 (0%)
Query: 13 LLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNKDALE 72
L++L CHFTW LL E ++ ++E+ I ++++FL TK + ++NLLAYVKHLKGQN++AL
Sbjct: 14 LIQLRCHFTWKLLIEAPEIPDLENRIWEEIQFLDTKYNVGIHNLLAYVKHLKGQNEEALV 73
Query: 73 CLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSN 132
L++AE++IQ+EH+++ ++RSLVTWGN+AWVYYHM +L EAQ Y K+ N CKK ++PS
Sbjct: 74 SLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSR 133
Query: 133 YKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDD-SD 191
Y++ECPE DCE+GWAL K GGK Y++AK FEKALE P+NPEFN GYAITVYRLD +
Sbjct: 134 YRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNT 193
Query: 192 REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYV 251
G K+FSL L++AV LNPD+ YI+V LALKLQD EAEGEKYIEE L ISSQ YV
Sbjct: 194 ASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYV 253
Query: 252 LRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGK 311
+YAAKFYRRK S +KALELLK ALE TPTS+FLHHQMGLCYRAQMIQIK+AT+ +P+G+
Sbjct: 254 FQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQMIQIKEATNWQPRGQ 313
Query: 312 DKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENIT 371
D+ VD L+ AI F+ + F AY DLA YAE G + AE+ F+K LR++
Sbjct: 314 DRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMKIFE 373
Query: 372 DDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHN 431
D K +IHYHYGRFQE H KS++ AI HYL+ LK++ S R KL +AL+KL+ + + N
Sbjct: 374 DQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSREKLLNALEKLAKRCIHQN 433
Query: 432 ALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKI 464
V+S+S LG ++KL+GE A YE+A ++
Sbjct: 434 VRVVESVSLLGLIHKLKGEVSDALLCYERALRL 466
>gi|153082755 interferon-induced protein with tetratricopeptide
repeats 2 [Homo sapiens]
Length = 472
Score = 403 bits (1035), Expect = e-112
Identities = 215/464 (46%), Positives = 299/464 (64%), Gaps = 13/464 (2%)
Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60
MSE K++L++ L +L+CHFTWNL++ + L + ED + + EF + + + NLLAY+
Sbjct: 1 MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60
Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120
KHLKGQN+ ALECL +AEE+IQQEH+D+ E+RSLVTWGNYAWVYYHM +L + Q Y K+
Sbjct: 61 KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120
Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180
+VC+K SSP Y++E PE DCE+GW LK GG ++AK FEKALE +P NPEF G
Sbjct: 121 KHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGL 178
Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKL----QDVHAEAEGEK 236
AI YRLD+ + ++ PLR+A+ LNPDN Y+KV LALKL ++ E EGEK
Sbjct: 179 AIASYRLDNWPPSQN----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEK 234
Query: 237 YIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQ 296
+EE L++ VLR AAKFYRRK+ +KA+ELLKKALE P +++LH Q+G CYRA+
Sbjct: 235 LVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAK 294
Query: 297 MIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSN 356
+ Q+ N GK KL ELI A+ H K A E + + LA+++A QY +
Sbjct: 295 VFQVMNLRENGMYGKRKLL--ELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYED 352
Query: 357 AEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKL 416
AE F+K E +T K +H YG FQ + K E+ AIHH++E +K+ +S + K+
Sbjct: 353 AEYYFQKEFSKE-LTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKM 411
Query: 417 TSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEK 460
L+K++ RL N D ++L L F+ +L + +QA E E+
Sbjct: 412 KDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSER 455
>gi|31542980 interferon-induced protein with tetratricopeptide
repeats 3 [Homo sapiens]
Length = 490
Score = 377 bits (968), Expect = e-104
Identities = 205/460 (44%), Positives = 291/460 (63%), Gaps = 20/460 (4%)
Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60
MSE+ K++L+ IL +L+CHFTWNL KED ++ED + Q+EFL T+ + +YNLLAY+
Sbjct: 1 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60
Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120
KHL G N+ ALECL QAEE+IQQEH+D+ E+RSLVTWGNYAWVYYH+ +L +AQ Y K+
Sbjct: 61 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120
Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180
CKK S+P Y +E E DCE+GW LK G ++AK FEKALE +P+NPEF+ G
Sbjct: 121 KQTCKKFSNP--YSIEYSELDCEEGWTQLKCGRN--ERAKVCFEKALEEKPNNPEFSSGL 176
Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240
AI +Y LD+ K FS L++A+ L+PDN Y+KV L LKLQ ++ EAEGE+++EE
Sbjct: 177 AIAMYHLDNHPE----KQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEE 232
Query: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300
L++ Q VLR AAKFYRRK +KA+EL ++ LE TP + +L+HQ+G CY+A++ Q+
Sbjct: 233 ALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQM 292
Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360
+ + G +K ++ L A+ + A+E+ AY+DLA + E Y
Sbjct: 293 QNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLETECYQTP--- 347
Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420
F K + D K Q H Y Q+++ KSE+TA+ H LE L + +S + ++
Sbjct: 348 FNK-----EVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQP 402
Query: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEK 460
+ +S L NA + L G ++K G+ QAA+ YEK
Sbjct: 403 QNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEK 440
>gi|72534658 interferon-induced protein with tetratricopeptide
repeats 3 [Homo sapiens]
Length = 490
Score = 377 bits (968), Expect = e-104
Identities = 205/460 (44%), Positives = 291/460 (63%), Gaps = 20/460 (4%)
Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60
MSE+ K++L+ IL +L+CHFTWNL KED ++ED + Q+EFL T+ + +YNLLAY+
Sbjct: 1 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60
Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120
KHL G N+ ALECL QAEE+IQQEH+D+ E+RSLVTWGNYAWVYYH+ +L +AQ Y K+
Sbjct: 61 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120
Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180
CKK S+P Y +E E DCE+GW LK G ++AK FEKALE +P+NPEF+ G
Sbjct: 121 KQTCKKFSNP--YSIEYSELDCEEGWTQLKCGRN--ERAKVCFEKALEEKPNNPEFSSGL 176
Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240
AI +Y LD+ K FS L++A+ L+PDN Y+KV L LKLQ ++ EAEGE+++EE
Sbjct: 177 AIAMYHLDNHPE----KQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEE 232
Query: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300
L++ Q VLR AAKFYRRK +KA+EL ++ LE TP + +L+HQ+G CY+A++ Q+
Sbjct: 233 ALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQM 292
Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360
+ + G +K ++ L A+ + A+E+ AY+DLA + E Y
Sbjct: 293 QNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLETECYQTP--- 347
Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420
F K + D K Q H Y Q+++ KSE+TA+ H LE L + +S + ++
Sbjct: 348 FNK-----EVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQP 402
Query: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEK 460
+ +S L NA + L G ++K G+ QAA+ YEK
Sbjct: 403 QNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEK 440
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 53.9 bits (128), Expect = 3e-07
Identities = 62/261 (23%), Positives = 104/261 (39%), Gaps = 39/261 (14%)
Query: 154 KYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPD 213
+ + +A AA+ +AL + P++ + A Y E + ++ R+A+ L P
Sbjct: 229 RIFDRAVAAYLRALSLSPNHAVVHGNLACVYY-------EQGLIDLAIDTYRRAIELQPH 281
Query: 214 NSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLK 273
LA L++ + AE E L + L A R + + +A+ L +
Sbjct: 282 FPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYR 341
Query: 274 KALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMER 333
KALEV P + H + A ++Q +GK + A+ H+K A+
Sbjct: 342 KALEVFPEFAAAHSNL-----ASVLQ--------QQGK--------LQEALMHYKEAIRI 380
Query: 334 DSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE-NITDDHKH--QIHYHYGRFQEFHR 390
FA AY+++ N E A + +A+++ D H + IH G E
Sbjct: 381 SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPE--- 437
Query: 391 KSENTAIHHYLEALKVKDRSP 411
AI Y ALK+K P
Sbjct: 438 -----AIASYRTALKLKPDFP 453
Score = 45.8 bits (107), Expect = 9e-05
Identities = 49/165 (29%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 326 HFKA-AMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGR 384
HF A++++ + A AY++L N+Y E GQ A + +R ALRL+ D +
Sbjct: 66 HFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVA 125
Query: 385 FQEFHRKSENTAIHHYLEALKVKD-----RSPLRTKLTSALKKLSTKRLCH-NALDVQ-- 436
+ A+ Y+ AL+ RS L L AL +L + C+ A++ Q
Sbjct: 126 AGDMEG-----AVQAYVSALQYNPDLYCVRSDLGN-LLKALGRLEEAKACYLKAIETQPN 179
Query: 437 ---SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478
+ S LG V+ +GE A ++EKA +DP FL A L
Sbjct: 180 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP---NFLDAYINL 221
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 53.9 bits (128), Expect = 3e-07
Identities = 62/261 (23%), Positives = 104/261 (39%), Gaps = 39/261 (14%)
Query: 154 KYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPD 213
+ + +A AA+ +AL + P++ + A Y E + ++ R+A+ L P
Sbjct: 239 RIFDRAVAAYLRALSLSPNHAVVHGNLACVYY-------EQGLIDLAIDTYRRAIELQPH 291
Query: 214 NSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLK 273
LA L++ + AE E L + L A R + + +A+ L +
Sbjct: 292 FPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYR 351
Query: 274 KALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMER 333
KALEV P + H + A ++Q +GK + A+ H+K A+
Sbjct: 352 KALEVFPEFAAAHSNL-----ASVLQ--------QQGK--------LQEALMHYKEAIRI 390
Query: 334 DSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE-NITDDHKH--QIHYHYGRFQEFHR 390
FA AY+++ N E A + +A+++ D H + IH G E
Sbjct: 391 SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPE--- 447
Query: 391 KSENTAIHHYLEALKVKDRSP 411
AI Y ALK+K P
Sbjct: 448 -----AIASYRTALKLKPDFP 463
Score = 45.8 bits (107), Expect = 9e-05
Identities = 49/165 (29%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 326 HFKA-AMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGR 384
HF A++++ + A AY++L N+Y E GQ A + +R ALRL+ D +
Sbjct: 76 HFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVA 135
Query: 385 FQEFHRKSENTAIHHYLEALKVKD-----RSPLRTKLTSALKKLSTKRLCH-NALDVQ-- 436
+ A+ Y+ AL+ RS L L AL +L + C+ A++ Q
Sbjct: 136 AGDMEG-----AVQAYVSALQYNPDLYCVRSDLGN-LLKALGRLEEAKACYLKAIETQPN 189
Query: 437 ---SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478
+ S LG V+ +GE A ++EKA +DP FL A L
Sbjct: 190 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP---NFLDAYINL 231
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 52.8 bits (125), Expect = 7e-07
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
Query: 314 LKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDD 373
LK E AI K +++ FA AY+ LA++ AE ++ AE+I++ ++ N D
Sbjct: 450 LKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIK--NCPD- 506
Query: 374 HKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPL---------RTKLTSALKKLS 424
+H +YG F E A+ HY +A+K+ + R+ +++ +
Sbjct: 507 -SSDLHNNYGVFLVDTGLPEK-AVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEW 564
Query: 425 TKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478
KR A + LS LG +Y G +A + Y++A + P E AL ++
Sbjct: 565 YKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQV 618
Score = 39.7 bits (91), Expect = 0.006
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 12/128 (9%)
Query: 358 EDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDR--SPLRTK 415
E +FR ++ T H ++HY+Y F + +++ AI+HY ALK+ R S L
Sbjct: 361 ESLFRSGVQ----TLPHNAKVHYNYANFLKDQGRNKE-AIYHYRTALKLYPRHASALNNL 415
Query: 416 LTSALKKLSTKRLCHNALDV-----QSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAE 470
T K AL + ++L LG + K + +K +A + + K PE A+
Sbjct: 416 GTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFAD 475
Query: 471 FLTALCEL 478
++L L
Sbjct: 476 AYSSLASL 483
Score = 38.5 bits (88), Expect = 0.014
Identities = 33/163 (20%), Positives = 72/163 (44%), Gaps = 17/163 (10%)
Query: 205 RKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNS 264
++A L P +++ LA L + E EK I+ + + R + Y ++ +
Sbjct: 599 QEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQEN 658
Query: 265 WNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAI 324
+KAL+ + KAL++ P + ++ KG ++L+ L+ A
Sbjct: 659 HDKALDAIDKALQLKPKDPKVISELFF----------------TKG-NQLREQNLLDKAF 701
Query: 325 FHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367
++ A++ + A A+ ++ + G+Y +A + +AL+L
Sbjct: 702 ESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQL 744
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 44.7 bits (104), Expect = 2e-04
Identities = 48/187 (25%), Positives = 83/187 (44%), Gaps = 9/187 (4%)
Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360
K+A + G D K + +A+ H+ A E D T+ A +Y E G Y+ ++
Sbjct: 223 KQALKEKELGNDAYKKKDF-DTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCREL 281
Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSE--NTAIHHYLEALKVKDRSPLRTKLTS 418
KA+ + + QI Y R + K E AIH Y ++L + R+P K
Sbjct: 282 CEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSL-AEHRTPDVLKKCQ 340
Query: 419 ALKKL--STKRLCHNALDVQ-SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLT-- 473
+K+ +RL + D+ G +G+ QA ++Y +A K +P++A+ +
Sbjct: 341 QAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNR 400
Query: 474 ALCELRL 480
A C +L
Sbjct: 401 AACYTKL 407
>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
Length = 860
Score = 42.7 bits (99), Expect = 7e-04
Identities = 61/276 (22%), Positives = 101/276 (36%), Gaps = 29/276 (10%)
Query: 117 TGKIGNVCKKLSSPSNYKL--ECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNP 174
T KI + K ++ + + T+ E A + G Y +A F L+ EPD
Sbjct: 118 TEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLV 177
Query: 175 EFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEG 234
G I + D + + +L L + +TL PD + A L + E
Sbjct: 178 SAIYGRGIAYGKKGLHDIKNA--ELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEA 235
Query: 235 EKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYR 294
+ + + Q+ + R+ Y + A E +++LE+ GL +
Sbjct: 236 VNDLTKAI-QLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFF 294
Query: 295 AQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQY 354
+ L+ AI FK A+++ F AY L Y E G +
Sbjct: 295 HR---------------------GLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNF 333
Query: 355 SNAEDIFRKALRLEN---ITDDHKHQIHYHYGRFQE 387
A + F+KAL L T + + YH+G QE
Sbjct: 334 EAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQE 369
>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
sapiens]
Length = 833
Score = 41.2 bits (95), Expect = 0.002
Identities = 79/347 (22%), Positives = 139/347 (40%), Gaps = 41/347 (11%)
Query: 156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFS---LGPLR----KAV 208
Y A ++E + + P+ GY +T+ DRE K+F PL K +
Sbjct: 297 YSDAINSYEHIMSMAPN---LKAGYNLTICYFAIGDREKMKKAFQKLITVPLEIDEDKYI 353
Query: 209 TLNPDNSYIKVFLALK---LQDVHAE--AEGEKYIEEILDQISSQPYVLRYAAKFYRRKN 263
+ + D V A+K L+ + E A EKYI I+ P + A Y
Sbjct: 354 SPSDDPHTNLVTEAIKNDHLRQMERERKAMAEKYIMTSAKLIA--PVIETSFAAGYDWCV 411
Query: 264 SWNKALELLKKA--LEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDEL-- 319
KA + ++ A LE+ ++L Q +++++ + +R K + L
Sbjct: 412 EVVKASQYVELANDLEINKAVTYLR-QKDYNQAVEILKVLEKKDSRVKSAAATNLSALYY 470
Query: 320 ----ISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHK 375
+ A + A+ D A T+ N G Y A + +++ALR ++ +
Sbjct: 471 MGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEAL 530
Query: 376 HQIHYHYGR----------FQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLST 425
+ I Y + F + H N+A Y ++ + L + A++ L
Sbjct: 531 YNIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLY----QIANIYELMENPSQAIEWLM- 585
Query: 426 KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFL 472
+ + D Q LS LG +Y EG+K QA +YY ++ + P N E +
Sbjct: 586 QVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVI 632
>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
sapiens]
Length = 824
Score = 41.2 bits (95), Expect = 0.002
Identities = 79/347 (22%), Positives = 139/347 (40%), Gaps = 41/347 (11%)
Query: 156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFS---LGPLR----KAV 208
Y A ++E + + P+ GY +T+ DRE K+F PL K +
Sbjct: 288 YSDAINSYEHIMSMAPN---LKAGYNLTICYFAIGDREKMKKAFQKLITVPLEIDEDKYI 344
Query: 209 TLNPDNSYIKVFLALK---LQDVHAE--AEGEKYIEEILDQISSQPYVLRYAAKFYRRKN 263
+ + D V A+K L+ + E A EKYI I+ P + A Y
Sbjct: 345 SPSDDPHTNLVTEAIKNDHLRQMERERKAMAEKYIMTSAKLIA--PVIETSFAAGYDWCV 402
Query: 264 SWNKALELLKKA--LEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDEL-- 319
KA + ++ A LE+ ++L Q +++++ + +R K + L
Sbjct: 403 EVVKASQYVELANDLEINKAVTYLR-QKDYNQAVEILKVLEKKDSRVKSAAATNLSALYY 461
Query: 320 ----ISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHK 375
+ A + A+ D A T+ N G Y A + +++ALR ++ +
Sbjct: 462 MGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEAL 521
Query: 376 HQIHYHYGR----------FQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLST 425
+ I Y + F + H N+A Y ++ + L + A++ L
Sbjct: 522 YNIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLY----QIANIYELMENPSQAIEWLM- 576
Query: 426 KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFL 472
+ + D Q LS LG +Y EG+K QA +YY ++ + P N E +
Sbjct: 577 QVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVI 623
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 39.7 bits (91), Expect = 0.006
Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 4/57 (7%)
Query: 430 HNALDVQ----SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRLSI 482
HNAL++ + LG ++ LEG+ +A E Y+KA + PEN E LT L L L +
Sbjct: 159 HNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQL 215
>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
sapiens]
Length = 807
Score = 39.7 bits (91), Expect = 0.006
Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 17/138 (12%)
Query: 266 NKALELLKKALEVTPTSSFLHHQMGLCYRAQ--------MIQIKKATHNRP-----KGKD 312
N+A+ L KA+++ P++ H+ L + ++ Q + N+P KG
Sbjct: 180 NEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLT 239
Query: 313 KLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEN--- 369
L+ AI FK A+++ F AY L Y E G + A + F+KAL L
Sbjct: 240 FFHRG-LLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHV 298
Query: 370 ITDDHKHQIHYHYGRFQE 387
T + + YH+G QE
Sbjct: 299 QTLQLRGMMLYHHGSLQE 316
>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
Length = 1564
Score = 38.1 bits (87), Expect = 0.018
Identities = 37/151 (24%), Positives = 63/151 (41%), Gaps = 32/151 (21%)
Query: 340 AYTDLANMYAEGG-------QYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKS 392
+Y DLA ++A Y AE F++AL + ++ +Q+ Y E RK
Sbjct: 415 SYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKD 474
Query: 393 ENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYK-LEGEK 451
+ A+ H+L+A + L K C+ LG Y+ + G+K
Sbjct: 475 KTKALTHFLKAAR--------------LDTYMGKVFCY----------LGHYYRDVVGDK 510
Query: 452 RQAAEYYEKAQKIDPENAEFLTALCELRLSI 482
+A Y KA ++D +AE A +L + +
Sbjct: 511 NRARGCYRKAFELDDTDAESGAAAVDLSVEL 541
Score = 34.7 bits (78), Expect = 0.20
Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 17/138 (12%)
Query: 233 EGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLC 292
E K +E++L V A + K + +A + ++ALE + H+Q+GL
Sbjct: 404 EAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLT 463
Query: 293 YRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAE-G 351
Y + + KDK K A+ HF A D+ + L + Y +
Sbjct: 464 YWFMGEETR---------KDKTK-------ALTHFLKAARLDTYMGKVFCYLGHYYRDVV 507
Query: 352 GQYSNAEDIFRKALRLEN 369
G + A +RKA L++
Sbjct: 508 GDKNRARGCYRKAFELDD 525
>gi|189011544 ubiquitously transcribed tetratricopeptide repeat, X
chromosome [Homo sapiens]
Length = 1401
Score = 35.0 bits (79), Expect = 0.15
Identities = 55/260 (21%), Positives = 104/260 (40%), Gaps = 40/260 (15%)
Query: 145 GWALLKFGGKYYQKAKAAFEKALEVEPD-----NPEFNIGYAITVYRLDDSDREGSVKSF 199
G L+ F +Q A AF++ L V+P +G V ++D E S+K F
Sbjct: 135 GLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKV----NTDYESSLKHF 190
Query: 200 SLGPLRKAVTLNP---DNSYIKVFLALKLQDVHAEAEGEKYIEEIL--DQISSQ--PYVL 252
L V NP N+ I+ +A + ++ E++L + +S+Q VL
Sbjct: 191 QLA----LVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVKATVL 246
Query: 253 RYAAKFYR-------RKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRA-QMIQIKKAT 304
+ + + + A++ L+K+LE P S + +G CY + +Q +
Sbjct: 247 QQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFIS 306
Query: 305 HNRPKGKDKLKVDELISSAIFH------------FKAAMERDSMFAFAYTDLANMYAEGG 352
+ + K + D S + + + A++ D A A+ DL +Y
Sbjct: 307 YRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCN 366
Query: 353 QYSNAEDIFRKALRLENITD 372
Q +A + A R ++ ++
Sbjct: 367 QPQDAIKCYLNATRSKSCSN 386
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 34.7 bits (78), Expect = 0.20
Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 19/129 (14%)
Query: 340 AYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRK-SENTAIH 398
AY ++ N Y G Y A R+ L++ +D Q H + + + A+
Sbjct: 516 AYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQ 575
Query: 399 HYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYY 458
HY L + + L + ++LS LG + GE QAA YY
Sbjct: 576 HYQNHLNI------------------ARELRDIQSEARALSNLGNFHCSRGEYVQAAPYY 617
Query: 459 EKAQKIDPE 467
E+ ++ P+
Sbjct: 618 EQYLRLAPD 626
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 34.3 bits (77), Expect = 0.26
Identities = 50/243 (20%), Positives = 99/243 (40%), Gaps = 40/243 (16%)
Query: 239 EEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMI 298
+++ D + P A + + + A++ ++A++V P ++ + +G
Sbjct: 563 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG-------- 614
Query: 299 QIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAE 358
+ + E + A+ F+ A+ + A+ L +Y + ++S AE
Sbjct: 615 -------------HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 661
Query: 359 DIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPL------ 412
F+KAL + + + H G Q +KSE A+ +A+ + ++PL
Sbjct: 662 MHFQKALDI----NPQSSVLLCHIGVVQHALKKSEK-ALDTLNKAIVIDPKNPLCKFHRA 716
Query: 413 -----RTKLTSALKKLST-KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDP 466
K SAL++L K++ V L +G VYK G+ A + A +DP
Sbjct: 717 SVLFANEKYKSALQELEELKQIVPKESLVYFL--IGKVYKKLGQTHLALMNFSWAMDLDP 774
Query: 467 ENA 469
+ A
Sbjct: 775 KGA 777
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 34.3 bits (77), Expect = 0.26
Identities = 50/243 (20%), Positives = 99/243 (40%), Gaps = 40/243 (16%)
Query: 239 EEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMI 298
+++ D + P A + + + A++ ++A++V P ++ + +G
Sbjct: 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG-------- 608
Query: 299 QIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAE 358
+ + E + A+ F+ A+ + A+ L +Y + ++S AE
Sbjct: 609 -------------HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655
Query: 359 DIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPL------ 412
F+KAL + + + H G Q +KSE A+ +A+ + ++PL
Sbjct: 656 MHFQKALDI----NPQSSVLLCHIGVVQHALKKSEK-ALDTLNKAIVIDPKNPLCKFHRA 710
Query: 413 -----RTKLTSALKKLST-KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDP 466
K SAL++L K++ V L +G VYK G+ A + A +DP
Sbjct: 711 SVLFANEKYKSALQELEELKQIVPKESLVYFL--IGKVYKKLGQTHLALMNFSWAMDLDP 768
Query: 467 ENA 469
+ A
Sbjct: 769 KGA 771
>gi|239741018 PREDICTED: hypothetical protein XP_002342056 [Homo
sapiens]
Length = 566
Score = 33.5 bits (75), Expect = 0.44
Identities = 57/215 (26%), Positives = 87/215 (40%), Gaps = 34/215 (15%)
Query: 163 FEKALEVEPDNPEFNIGYAITVYRLDDSDR--EGSVKSFSLGP---LRKAVTLNPDN--- 214
F L EP N + G A+ LD + V + LGP + + +L P+
Sbjct: 201 FNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGTVVPELRSLKPEAQAL 260
Query: 215 ------SYIKVFLALKLQDVHA-----EAEGEKYIEEILDQISS-QPYVLRYAAKFYRRK 262
S+ + L+ +L D A + +G + E L +I S QP+ A +
Sbjct: 261 ITQGLYSHCRALLS-QLPDTGAPLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQ 319
Query: 263 NSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKL----KVDE 318
S+ +A L+KAL PTS ++GL +Q+KK + P L +VD
Sbjct: 320 GSYEEAGTHLEKALHRAPTSEAARARLGL------LQLKKG--DVPGAARDLQSLAEVDA 371
Query: 319 LISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQ 353
S + H A ER S+ A A A + GQ
Sbjct: 372 PDLSCLLHLLEASERQSL-AQAAAQEAGTLLDAGQ 405
>gi|4557269 adenylosuccinate lyase isoform a [Homo sapiens]
Length = 484
Score = 33.1 bits (74), Expect = 0.58
Identities = 22/109 (20%), Positives = 48/109 (44%), Gaps = 10/109 (9%)
Query: 34 VEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNKDALECL----EQAEEIIQQEHSDKE 89
+E I Q+L F+ T+ N++ + G +D E + +QA +++QE D +
Sbjct: 369 IERRIRQELPFMATE------NIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDND 422
Query: 90 EVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECP 138
+ + ++ ++ +D L + +TG+ ++ Y L P
Sbjct: 423 LIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKP 471
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 33.1 bits (74), Expect = 0.58
Identities = 44/200 (22%), Positives = 78/200 (39%), Gaps = 24/200 (12%)
Query: 103 VYYH-------MDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLK--FGG 153
VY+H +DQ+EEA + C +L + E +K +AL + + G
Sbjct: 403 VYHHRGQLKILLDQVEEAVADFDE----CIRL------RPESALAQAQKCFALYRQAYTG 452
Query: 154 KYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPD 213
+ +AA + EV P GYA+ L D + G K + L PD
Sbjct: 453 NNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEM----YDKCIDLEPD 508
Query: 214 NSYIKVFLAL-KLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELL 272
N+ V L +LQ G + I + ++ + + ++ + KA+++
Sbjct: 509 NATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMF 568
Query: 273 KKALEVTPTSSFLHHQMGLC 292
KA+ + + + H LC
Sbjct: 569 NKAINLAKSEMEMAHLYSLC 588
Score = 32.3 bits (72), Expect = 0.98
Identities = 51/236 (21%), Positives = 90/236 (38%), Gaps = 45/236 (19%)
Query: 147 ALLKFGGKYYQKAKAA-----FEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSL 201
AL+K G Y Q+ + F A +++P N + LD E +V F
Sbjct: 369 ALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQV--EEAVADFD- 425
Query: 202 GPLRKAVTLNPDNS----------YIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYV 251
+ + L P+++ Y + + + A +G EE++ +
Sbjct: 426 ----ECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKG---FEEVIKKFPRCAEG 478
Query: 252 LRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGK 311
A+ + + KA E+ K +++ P ++ + GL +Q K+
Sbjct: 479 YALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLL----QLQWKQ--------- 525
Query: 312 DKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367
D + ELIS AI E D+ FAY + + + G A D+F KA+ L
Sbjct: 526 DLDRGLELISKAI-------EIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINL 574
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 33.1 bits (74), Expect = 0.58
Identities = 50/248 (20%), Positives = 95/248 (38%), Gaps = 34/248 (13%)
Query: 251 VLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHN---- 306
++ Y K R W L + ++V P ++ + L ++++ + + A N
Sbjct: 463 IVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGNVLKSQSKISEAESAYRNALYY 522
Query: 307 RPKGKDKL-------KVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAED 359
R D L + + + A+ ++K A+ A AY + + G+ A
Sbjct: 523 RSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARR 582
Query: 360 IFRKALRL--ENITDDHKHQIH-----YHYGRFQEFHRKSE-NTAIHHYLEALKVKDRS- 410
F K + EN+ D H H+ Y+ G+ +H + A+ Y EA++ R
Sbjct: 583 TFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKL--YHEQGHYEEALSVYKEAIQKMPRQF 640
Query: 411 ---PLRTKLTSALKKLST---------KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYY 458
L + A +LS + L + + G + L G K +A + +
Sbjct: 641 APQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKLF 700
Query: 459 EKAQKIDP 466
KA ++DP
Sbjct: 701 LKAIELDP 708
>gi|144446030 lymphocyte antigen 75 [Homo sapiens]
Length = 1722
Score = 33.1 bits (74), Expect = 0.58
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Query: 309 KGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE 368
K ++L++ SSA+ +K E S++ A LA G SNA D+++K E
Sbjct: 90 KSVNELRMFSCDSSAMLWWKC--EHHSLYGAARYRLALKDGHGTAISNASDVWKKGGSEE 147
Query: 369 NITDDHKHQIHYH----YGRFQEF 388
++ D H+I+ YGR EF
Sbjct: 148 SLCDQPYHEIYTRDGNSYGRPCEF 171
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 32.3 bits (72), Expect = 0.98
Identities = 40/208 (19%), Positives = 86/208 (41%), Gaps = 30/208 (14%)
Query: 83 QEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDC 142
+E + K ++S + AW +D++ + K + + LS S + + D
Sbjct: 77 REENTKNRIKS---YDYEAWAKLDVDRILDE---LDKDDSTHESLSQESESEEDGIHVDS 130
Query: 143 EKGWALLKFGGKYYQKAKA-----AFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVK 197
+K L + G KY+++ K + K ++ +P NP A +RL K
Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL---------K 181
Query: 198 SFSLGPLRKAVTLNPDNSYIKV--------FLALKLQDVHAEAEGEKYIEEILDQISSQP 249
F++ + + + SY K F KL++ A+ + E+ +E + +
Sbjct: 182 KFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE--AKKDYERVLELEPNNFEATN 239
Query: 250 YVLRYAAKFYRRKNSWNKALELLKKALE 277
+ + + ++NS+ K +++ K+ E
Sbjct: 240 ELRKISQALASKENSYPKEADIVIKSTE 267
Score = 29.6 bits (65), Expect = 6.4
Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 33/159 (20%)
Query: 47 TKSRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQE--------HSDKEEVRSLVTWG 98
TK+R+ Y+ A+ K + D L+ + E + QE H D ++ L G
Sbjct: 81 TKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKG 140
Query: 99 NYAWVYYHMDQLEEA-QKYTGKIG----NVCKKLSSPSNY----KLECPETDCEKGWALL 149
N Y+ + +EA YT + N + S Y K E+DC AL
Sbjct: 141 NK---YFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALN 197
Query: 150 KFGGKYY-------------QKAKAAFEKALEVEPDNPE 175
+ K Y ++AK +E+ LE+EP+N E
Sbjct: 198 RSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFE 236
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 32.3 bits (72), Expect = 0.98
Identities = 40/208 (19%), Positives = 86/208 (41%), Gaps = 30/208 (14%)
Query: 83 QEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDC 142
+E + K ++S + AW +D++ + K + + LS S + + D
Sbjct: 77 REENTKNRIKS---YDYEAWAKLDVDRILDE---LDKDDSTHESLSQESESEEDGIHVDS 130
Query: 143 EKGWALLKFGGKYYQKAKA-----AFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVK 197
+K L + G KY+++ K + K ++ +P NP A +RL K
Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL---------K 181
Query: 198 SFSLGPLRKAVTLNPDNSYIKV--------FLALKLQDVHAEAEGEKYIEEILDQISSQP 249
F++ + + + SY K F KL++ A+ + E+ +E + +
Sbjct: 182 KFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE--AKKDYERVLELEPNNFEATN 239
Query: 250 YVLRYAAKFYRRKNSWNKALELLKKALE 277
+ + + ++NS+ K +++ K+ E
Sbjct: 240 ELRKISQALASKENSYPKEADIVIKSTE 267
Score = 29.6 bits (65), Expect = 6.4
Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 33/159 (20%)
Query: 47 TKSRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQE--------HSDKEEVRSLVTWG 98
TK+R+ Y+ A+ K + D L+ + E + QE H D ++ L G
Sbjct: 81 TKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKG 140
Query: 99 NYAWVYYHMDQLEEA-QKYTGKIG----NVCKKLSSPSNY----KLECPETDCEKGWALL 149
N Y+ + +EA YT + N + S Y K E+DC AL
Sbjct: 141 NK---YFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALN 197
Query: 150 KFGGKYY-------------QKAKAAFEKALEVEPDNPE 175
+ K Y ++AK +E+ LE+EP+N E
Sbjct: 198 RSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFE 236
>gi|52630440 FK506-binding protein 8 [Homo sapiens]
Length = 413
Score = 32.0 bits (71), Expect = 1.3
Identities = 39/165 (23%), Positives = 64/165 (38%), Gaps = 29/165 (17%)
Query: 256 AKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLK 315
A F NS++ A++ + + +V T AQ++Q+K N +LK
Sbjct: 236 ADFVLAANSYDLAIKAITSSAKVDMTFE---------EEAQLLQLKVKCLNN-LAASQLK 285
Query: 316 VDELISSAIFHFKAAMERDSMFAFAYTD-------LANMYAEGGQYSNAEDIFRKALRLE 368
+D H++AA+ S+ D + A+ G+YS A I R AL+LE
Sbjct: 286 LD--------HYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLE 337
Query: 369 NITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLR 413
IH + + H +T Y + L R P +
Sbjct: 338 ----PSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAK 378
>gi|28603842 tetratricopeptide repeat domain 9C [Homo sapiens]
Length = 171
Score = 32.0 bits (71), Expect = 1.3
Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 9/106 (8%)
Query: 135 LECPETDCEKGWA--LLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDR 192
L +TDC A LL+ Y++ + +K LE +PDN + + + L D D+
Sbjct: 67 LHTTQTDCYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDQ 126
Query: 193 EGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYI 238
L AV P ++ ++ +L L ++ + EK +
Sbjct: 127 ARHY-------LLAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQL 165
>gi|118766328 transmembrane and tetratricopeptide repeat containing
4 isoform 2 [Homo sapiens]
Length = 741
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 21/108 (19%)
Query: 261 RKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELI 320
R W +L + AL V P ++ +H+ +G + KG
Sbjct: 460 RSGEWRSEEQLFRSALSVCPLNAKVHYNIG-------------KNLADKGNQ-------- 498
Query: 321 SSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE 368
++AI +++ A+ + + A +L N+ E + AE++ A++++
Sbjct: 499 TAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQ 546
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,779,039
Number of Sequences: 37866
Number of extensions: 698736
Number of successful extensions: 2398
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 2226
Number of HSP's gapped (non-prelim): 164
length of query: 482
length of database: 18,247,518
effective HSP length: 106
effective length of query: 376
effective length of database: 14,233,722
effective search space: 5351879472
effective search space used: 5351879472
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.