BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|6912630 interferon-induced protein with tetratricopeptide repeats 5 [Homo sapiens] (482 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|6912630 interferon-induced protein with tetratricopeptide rep... 971 0.0 gi|116534937 interferon-induced protein with tetratricopeptide r... 538 e-153 gi|58330892 interferon-induced protein with tetratricopeptide re... 520 e-147 gi|153082755 interferon-induced protein with tetratricopeptide r... 403 e-112 gi|31542980 interferon-induced protein with tetratricopeptide re... 377 e-104 gi|72534658 interferon-induced protein with tetratricopeptide re... 377 e-104 gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 54 3e-07 gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 54 3e-07 gi|83415184 transmembrane and tetratricopeptide repeat containin... 53 7e-07 gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 45 2e-04 gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 43 7e-04 gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ... 41 0.002 gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ... 41 0.002 gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 40 0.006 gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 40 0.006 gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 38 0.018 gi|189011544 ubiquitously transcribed tetratricopeptide repeat, ... 35 0.15 gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 35 0.20 gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 34 0.26 gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 34 0.26 gi|239741018 PREDICTED: hypothetical protein XP_002342056 [Homo ... 33 0.44 gi|4557269 adenylosuccinate lyase isoform a [Homo sapiens] 33 0.58 gi|54607135 translocase of outer mitochondrial membrane 70 homol... 33 0.58 gi|22749211 transmembrane and tetratricopeptide repeat containin... 33 0.58 gi|144446030 lymphocyte antigen 75 [Homo sapiens] 33 0.58 gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 32 0.98 gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 32 0.98 gi|52630440 FK506-binding protein 8 [Homo sapiens] 32 1.3 gi|28603842 tetratricopeptide repeat domain 9C [Homo sapiens] 32 1.3 gi|118766328 transmembrane and tetratricopeptide repeat containi... 32 1.3 >gi|6912630 interferon-induced protein with tetratricopeptide repeats 5 [Homo sapiens] Length = 482 Score = 971 bits (2510), Expect = 0.0 Identities = 482/482 (100%), Positives = 482/482 (100%) Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV Sbjct: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI Sbjct: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY Sbjct: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE Sbjct: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240 Query: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI Sbjct: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300 Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI Sbjct: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360 Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL Sbjct: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420 Query: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 480 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL Sbjct: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 480 Query: 481 SI 482 SI Sbjct: 481 SI 482 >gi|116534937 interferon-induced protein with tetratricopeptide repeats 1 isoform 2 [Homo sapiens] Length = 478 Score = 538 bits (1385), Expect = e-153 Identities = 266/464 (57%), Positives = 351/464 (75%), Gaps = 3/464 (0%) Query: 9 LKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNK 68 +K L +L CHFTW L +D ++ ++E+ + Q+EFL TK + ++NLLAYVKHLKGQN+ Sbjct: 10 VKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNE 69 Query: 69 DALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLS 128 +AL+ L++AE ++Q+EH ++ VRSLVTWGN+AW+YYHM +L EAQ Y K+ N+CKKLS Sbjct: 70 EALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLS 129 Query: 129 SPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLD 188 +P Y++ECPE DCE+GWALLK GGK Y++AKA FEK LEV+P+NPE + GYAI+ YRLD Sbjct: 130 NPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLD 189 Query: 189 DSD-REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISS 247 + K FSL PLR+AV LNPDN YIKV LALKLQD EAEGEKYIEE L +SS Sbjct: 190 GFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSS 249 Query: 248 QPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNR 307 Q YV RYAAKFYRRK S +KALELLKKAL+ TPTS LHHQ+GLCY+AQMIQIK+AT + Sbjct: 250 QTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQ 309 Query: 308 PKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367 P+G+++ K+D++I SAIFHF++A+E+ F A+ DLA MY E G + AE+ F+K L + Sbjct: 310 PRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCM 369 Query: 368 ENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKR 427 + + ++ IH+HYGRFQEF +KS+ AI HYL+A+K++ S R K ++LKKL ++ Sbjct: 370 KPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRK 429 Query: 428 LCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKI--DPENA 469 L ALD++SLS LGFVYKLEG +A EYYE+A ++ D EN+ Sbjct: 430 LRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENS 473 >gi|58330892 interferon-induced protein with tetratricopeptide repeats 1-like [Homo sapiens] Length = 474 Score = 520 bits (1339), Expect = e-147 Identities = 258/453 (56%), Positives = 337/453 (74%), Gaps = 1/453 (0%) Query: 13 LLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNKDALE 72 L++L CHFTW LL E ++ ++E+ I ++++FL TK + ++NLLAYVKHLKGQN++AL Sbjct: 14 LIQLRCHFTWKLLIEAPEIPDLENRIWEEIQFLDTKYNVGIHNLLAYVKHLKGQNEEALV 73 Query: 73 CLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSN 132 L++AE++IQ+EH+++ ++RSLVTWGN+AWVYYHM +L EAQ Y K+ N CKK ++PS Sbjct: 74 SLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSR 133 Query: 133 YKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDD-SD 191 Y++ECPE DCE+GWAL K GGK Y++AK FEKALE P+NPEFN GYAITVYRLD + Sbjct: 134 YRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNT 193 Query: 192 REGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYV 251 G K+FSL L++AV LNPD+ YI+V LALKLQD EAEGEKYIEE L ISSQ YV Sbjct: 194 ASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYV 253 Query: 252 LRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGK 311 +YAAKFYRRK S +KALELLK ALE TPTS+FLHHQMGLCYRAQMIQIK+AT+ +P+G+ Sbjct: 254 FQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQMIQIKEATNWQPRGQ 313 Query: 312 DKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENIT 371 D+ VD L+ AI F+ + F AY DLA YAE G + AE+ F+K LR++ Sbjct: 314 DRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMKIFE 373 Query: 372 DDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHN 431 D K +IHYHYGRFQE H KS++ AI HYL+ LK++ S R KL +AL+KL+ + + N Sbjct: 374 DQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSREKLLNALEKLAKRCIHQN 433 Query: 432 ALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKI 464 V+S+S LG ++KL+GE A YE+A ++ Sbjct: 434 VRVVESVSLLGLIHKLKGEVSDALLCYERALRL 466 >gi|153082755 interferon-induced protein with tetratricopeptide repeats 2 [Homo sapiens] Length = 472 Score = 403 bits (1035), Expect = e-112 Identities = 215/464 (46%), Positives = 299/464 (64%), Gaps = 13/464 (2%) Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 MSE K++L++ L +L+CHFTWNL++ + L + ED + + EF + + + NLLAY+ Sbjct: 1 MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60 Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 KHLKGQN+ ALECL +AEE+IQQEH+D+ E+RSLVTWGNYAWVYYHM +L + Q Y K+ Sbjct: 61 KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120 Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 +VC+K SSP Y++E PE DCE+GW LK GG ++AK FEKALE +P NPEF G Sbjct: 121 KHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGL 178 Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKL----QDVHAEAEGEK 236 AI YRLD+ + ++ PLR+A+ LNPDN Y+KV LALKL ++ E EGEK Sbjct: 179 AIASYRLDNWPPSQN----AIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEK 234 Query: 237 YIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQ 296 +EE L++ VLR AAKFYRRK+ +KA+ELLKKALE P +++LH Q+G CYRA+ Sbjct: 235 LVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAK 294 Query: 297 MIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSN 356 + Q+ N GK KL ELI A+ H K A E + + LA+++A QY + Sbjct: 295 VFQVMNLRENGMYGKRKLL--ELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYED 352 Query: 357 AEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKL 416 AE F+K E +T K +H YG FQ + K E+ AIHH++E +K+ +S + K+ Sbjct: 353 AEYYFQKEFSKE-LTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKM 411 Query: 417 TSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEK 460 L+K++ RL N D ++L L F+ +L + +QA E E+ Sbjct: 412 KDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSER 455 >gi|31542980 interferon-induced protein with tetratricopeptide repeats 3 [Homo sapiens] Length = 490 Score = 377 bits (968), Expect = e-104 Identities = 205/460 (44%), Positives = 291/460 (63%), Gaps = 20/460 (4%) Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 MSE+ K++L+ IL +L+CHFTWNL KED ++ED + Q+EFL T+ + +YNLLAY+ Sbjct: 1 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60 Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 KHL G N+ ALECL QAEE+IQQEH+D+ E+RSLVTWGNYAWVYYH+ +L +AQ Y K+ Sbjct: 61 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120 Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 CKK S+P Y +E E DCE+GW LK G ++AK FEKALE +P+NPEF+ G Sbjct: 121 KQTCKKFSNP--YSIEYSELDCEEGWTQLKCGRN--ERAKVCFEKALEEKPNNPEFSSGL 176 Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240 AI +Y LD+ K FS L++A+ L+PDN Y+KV L LKLQ ++ EAEGE+++EE Sbjct: 177 AIAMYHLDNHPE----KQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEE 232 Query: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300 L++ Q VLR AAKFYRRK +KA+EL ++ LE TP + +L+HQ+G CY+A++ Q+ Sbjct: 233 ALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQM 292 Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360 + + G +K ++ L A+ + A+E+ AY+DLA + E Y Sbjct: 293 QNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLETECYQTP--- 347 Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420 F K + D K Q H Y Q+++ KSE+TA+ H LE L + +S + ++ Sbjct: 348 FNK-----EVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQP 402 Query: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEK 460 + +S L NA + L G ++K G+ QAA+ YEK Sbjct: 403 QNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEK 440 >gi|72534658 interferon-induced protein with tetratricopeptide repeats 3 [Homo sapiens] Length = 490 Score = 377 bits (968), Expect = e-104 Identities = 205/460 (44%), Positives = 291/460 (63%), Gaps = 20/460 (4%) Query: 1 MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60 MSE+ K++L+ IL +L+CHFTWNL KED ++ED + Q+EFL T+ + +YNLLAY+ Sbjct: 1 MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60 Query: 61 KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120 KHL G N+ ALECL QAEE+IQQEH+D+ E+RSLVTWGNYAWVYYH+ +L +AQ Y K+ Sbjct: 61 KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120 Query: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180 CKK S+P Y +E E DCE+GW LK G ++AK FEKALE +P+NPEF+ G Sbjct: 121 KQTCKKFSNP--YSIEYSELDCEEGWTQLKCGRN--ERAKVCFEKALEEKPNNPEFSSGL 176 Query: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240 AI +Y LD+ K FS L++A+ L+PDN Y+KV L LKLQ ++ EAEGE+++EE Sbjct: 177 AIAMYHLDNHPE----KQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEE 232 Query: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300 L++ Q VLR AAKFYRRK +KA+EL ++ LE TP + +L+HQ+G CY+A++ Q+ Sbjct: 233 ALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQM 292 Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360 + + G +K ++ L A+ + A+E+ AY+DLA + E Y Sbjct: 293 QNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLETECYQTP--- 347 Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420 F K + D K Q H Y Q+++ KSE+TA+ H LE L + +S + ++ Sbjct: 348 FNK-----EVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQP 402 Query: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEK 460 + +S L NA + L G ++K G+ QAA+ YEK Sbjct: 403 QNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEK 440 >gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] Length = 1036 Score = 53.9 bits (128), Expect = 3e-07 Identities = 62/261 (23%), Positives = 104/261 (39%), Gaps = 39/261 (14%) Query: 154 KYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPD 213 + + +A AA+ +AL + P++ + A Y E + ++ R+A+ L P Sbjct: 229 RIFDRAVAAYLRALSLSPNHAVVHGNLACVYY-------EQGLIDLAIDTYRRAIELQPH 281 Query: 214 NSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLK 273 LA L++ + AE E L + L A R + + +A+ L + Sbjct: 282 FPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYR 341 Query: 274 KALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMER 333 KALEV P + H + A ++Q +GK + A+ H+K A+ Sbjct: 342 KALEVFPEFAAAHSNL-----ASVLQ--------QQGK--------LQEALMHYKEAIRI 380 Query: 334 DSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE-NITDDHKH--QIHYHYGRFQEFHR 390 FA AY+++ N E A + +A+++ D H + IH G E Sbjct: 381 SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPE--- 437 Query: 391 KSENTAIHHYLEALKVKDRSP 411 AI Y ALK+K P Sbjct: 438 -----AIASYRTALKLKPDFP 453 Score = 45.8 bits (107), Expect = 9e-05 Identities = 49/165 (29%), Positives = 76/165 (46%), Gaps = 21/165 (12%) Query: 326 HFKA-AMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGR 384 HF A++++ + A AY++L N+Y E GQ A + +R ALRL+ D + Sbjct: 66 HFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVA 125 Query: 385 FQEFHRKSENTAIHHYLEALKVKD-----RSPLRTKLTSALKKLSTKRLCH-NALDVQ-- 436 + A+ Y+ AL+ RS L L AL +L + C+ A++ Q Sbjct: 126 AGDMEG-----AVQAYVSALQYNPDLYCVRSDLGN-LLKALGRLEEAKACYLKAIETQPN 179 Query: 437 ---SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 + S LG V+ +GE A ++EKA +DP FL A L Sbjct: 180 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP---NFLDAYINL 221 >gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] Length = 1046 Score = 53.9 bits (128), Expect = 3e-07 Identities = 62/261 (23%), Positives = 104/261 (39%), Gaps = 39/261 (14%) Query: 154 KYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPD 213 + + +A AA+ +AL + P++ + A Y E + ++ R+A+ L P Sbjct: 239 RIFDRAVAAYLRALSLSPNHAVVHGNLACVYY-------EQGLIDLAIDTYRRAIELQPH 291 Query: 214 NSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLK 273 LA L++ + AE E L + L A R + + +A+ L + Sbjct: 292 FPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYR 351 Query: 274 KALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMER 333 KALEV P + H + A ++Q +GK + A+ H+K A+ Sbjct: 352 KALEVFPEFAAAHSNL-----ASVLQ--------QQGK--------LQEALMHYKEAIRI 390 Query: 334 DSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE-NITDDHKH--QIHYHYGRFQEFHR 390 FA AY+++ N E A + +A+++ D H + IH G E Sbjct: 391 SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPE--- 447 Query: 391 KSENTAIHHYLEALKVKDRSP 411 AI Y ALK+K P Sbjct: 448 -----AIASYRTALKLKPDFP 463 Score = 45.8 bits (107), Expect = 9e-05 Identities = 49/165 (29%), Positives = 76/165 (46%), Gaps = 21/165 (12%) Query: 326 HFKA-AMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGR 384 HF A++++ + A AY++L N+Y E GQ A + +R ALRL+ D + Sbjct: 76 HFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVA 135 Query: 385 FQEFHRKSENTAIHHYLEALKVKD-----RSPLRTKLTSALKKLSTKRLCH-NALDVQ-- 436 + A+ Y+ AL+ RS L L AL +L + C+ A++ Q Sbjct: 136 AGDMEG-----AVQAYVSALQYNPDLYCVRSDLGN-LLKALGRLEEAKACYLKAIETQPN 189 Query: 437 ---SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 + S LG V+ +GE A ++EKA +DP FL A L Sbjct: 190 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP---NFLDAYINL 231 >gi|83415184 transmembrane and tetratricopeptide repeat containing 1 [Homo sapiens] Length = 774 Score = 52.8 bits (125), Expect = 7e-07 Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 14/174 (8%) Query: 314 LKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDD 373 LK E AI K +++ FA AY+ LA++ AE ++ AE+I++ ++ N D Sbjct: 450 LKSQEKKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIK--NCPD- 506 Query: 374 HKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPL---------RTKLTSALKKLS 424 +H +YG F E A+ HY +A+K+ + R+ +++ + Sbjct: 507 -SSDLHNNYGVFLVDTGLPEK-AVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEW 564 Query: 425 TKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478 KR A + LS LG +Y G +A + Y++A + P E AL ++ Sbjct: 565 YKRALQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQV 618 Score = 39.7 bits (91), Expect = 0.006 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 12/128 (9%) Query: 358 EDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDR--SPLRTK 415 E +FR ++ T H ++HY+Y F + +++ AI+HY ALK+ R S L Sbjct: 361 ESLFRSGVQ----TLPHNAKVHYNYANFLKDQGRNKE-AIYHYRTALKLYPRHASALNNL 415 Query: 416 LTSALKKLSTKRLCHNALDV-----QSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAE 470 T K AL + ++L LG + K + +K +A + + K PE A+ Sbjct: 416 GTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFAD 475 Query: 471 FLTALCEL 478 ++L L Sbjct: 476 AYSSLASL 483 Score = 38.5 bits (88), Expect = 0.014 Identities = 33/163 (20%), Positives = 72/163 (44%), Gaps = 17/163 (10%) Query: 205 RKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNS 264 ++A L P +++ LA L + E EK I+ + + R + Y ++ + Sbjct: 599 QEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQEN 658 Query: 265 WNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAI 324 +KAL+ + KAL++ P + ++ KG ++L+ L+ A Sbjct: 659 HDKALDAIDKALQLKPKDPKVISELFF----------------TKG-NQLREQNLLDKAF 701 Query: 325 FHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367 ++ A++ + A A+ ++ + G+Y +A + +AL+L Sbjct: 702 ESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQL 744 >gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein) [Homo sapiens] Length = 543 Score = 44.7 bits (104), Expect = 2e-04 Identities = 48/187 (25%), Positives = 83/187 (44%), Gaps = 9/187 (4%) Query: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360 K+A + G D K + +A+ H+ A E D T+ A +Y E G Y+ ++ Sbjct: 223 KQALKEKELGNDAYKKKDF-DTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCREL 281 Query: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSE--NTAIHHYLEALKVKDRSPLRTKLTS 418 KA+ + + QI Y R + K E AIH Y ++L + R+P K Sbjct: 282 CEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNKSL-AEHRTPDVLKKCQ 340 Query: 419 ALKKL--STKRLCHNALDVQ-SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLT-- 473 +K+ +RL + D+ G +G+ QA ++Y +A K +P++A+ + Sbjct: 341 QAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNR 400 Query: 474 ALCELRL 480 A C +L Sbjct: 401 AACYTKL 407 >gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo sapiens] Length = 860 Score = 42.7 bits (99), Expect = 7e-04 Identities = 61/276 (22%), Positives = 101/276 (36%), Gaps = 29/276 (10%) Query: 117 TGKIGNVCKKLSSPSNYKL--ECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNP 174 T KI + K ++ + + T+ E A + G Y +A F L+ EPD Sbjct: 118 TEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLV 177 Query: 175 EFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEG 234 G I + D + + +L L + +TL PD + A L + E Sbjct: 178 SAIYGRGIAYGKKGLHDIKNA--ELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEA 235 Query: 235 EKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYR 294 + + + Q+ + R+ Y + A E +++LE+ GL + Sbjct: 236 VNDLTKAI-QLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFF 294 Query: 295 AQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQY 354 + L+ AI FK A+++ F AY L Y E G + Sbjct: 295 HR---------------------GLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNF 333 Query: 355 SNAEDIFRKALRLEN---ITDDHKHQIHYHYGRFQE 387 A + F+KAL L T + + YH+G QE Sbjct: 334 EAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQE 369 >gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo sapiens] Length = 833 Score = 41.2 bits (95), Expect = 0.002 Identities = 79/347 (22%), Positives = 139/347 (40%), Gaps = 41/347 (11%) Query: 156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFS---LGPLR----KAV 208 Y A ++E + + P+ GY +T+ DRE K+F PL K + Sbjct: 297 YSDAINSYEHIMSMAPN---LKAGYNLTICYFAIGDREKMKKAFQKLITVPLEIDEDKYI 353 Query: 209 TLNPDNSYIKVFLALK---LQDVHAE--AEGEKYIEEILDQISSQPYVLRYAAKFYRRKN 263 + + D V A+K L+ + E A EKYI I+ P + A Y Sbjct: 354 SPSDDPHTNLVTEAIKNDHLRQMERERKAMAEKYIMTSAKLIA--PVIETSFAAGYDWCV 411 Query: 264 SWNKALELLKKA--LEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDEL-- 319 KA + ++ A LE+ ++L Q +++++ + +R K + L Sbjct: 412 EVVKASQYVELANDLEINKAVTYLR-QKDYNQAVEILKVLEKKDSRVKSAAATNLSALYY 470 Query: 320 ----ISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHK 375 + A + A+ D A T+ N G Y A + +++ALR ++ + Sbjct: 471 MGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEAL 530 Query: 376 HQIHYHYGR----------FQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLST 425 + I Y + F + H N+A Y ++ + L + A++ L Sbjct: 531 YNIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLY----QIANIYELMENPSQAIEWLM- 585 Query: 426 KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFL 472 + + D Q LS LG +Y EG+K QA +YY ++ + P N E + Sbjct: 586 QVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVI 632 >gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo sapiens] Length = 824 Score = 41.2 bits (95), Expect = 0.002 Identities = 79/347 (22%), Positives = 139/347 (40%), Gaps = 41/347 (11%) Query: 156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFS---LGPLR----KAV 208 Y A ++E + + P+ GY +T+ DRE K+F PL K + Sbjct: 288 YSDAINSYEHIMSMAPN---LKAGYNLTICYFAIGDREKMKKAFQKLITVPLEIDEDKYI 344 Query: 209 TLNPDNSYIKVFLALK---LQDVHAE--AEGEKYIEEILDQISSQPYVLRYAAKFYRRKN 263 + + D V A+K L+ + E A EKYI I+ P + A Y Sbjct: 345 SPSDDPHTNLVTEAIKNDHLRQMERERKAMAEKYIMTSAKLIA--PVIETSFAAGYDWCV 402 Query: 264 SWNKALELLKKA--LEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDEL-- 319 KA + ++ A LE+ ++L Q +++++ + +R K + L Sbjct: 403 EVVKASQYVELANDLEINKAVTYLR-QKDYNQAVEILKVLEKKDSRVKSAAATNLSALYY 461 Query: 320 ----ISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHK 375 + A + A+ D A T+ N G Y A + +++ALR ++ + Sbjct: 462 MGKDFAQASSYADIAVNSDRYNPAALTNKGNTVFANGDYEKAAEFYKEALRNDSSCTEAL 521 Query: 376 HQIHYHYGR----------FQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLST 425 + I Y + F + H N+A Y ++ + L + A++ L Sbjct: 522 YNIGLTYEKLNRLDEALDCFLKLHAILRNSAEVLY----QIANIYELMENPSQAIEWLM- 576 Query: 426 KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFL 472 + + D Q LS LG +Y EG+K QA +YY ++ + P N E + Sbjct: 577 QVVSVIPTDPQVLSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVI 623 >gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] Length = 519 Score = 39.7 bits (91), Expect = 0.006 Identities = 23/57 (40%), Positives = 33/57 (57%), Gaps = 4/57 (7%) Query: 430 HNALDVQ----SLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRLSI 482 HNAL++ + LG ++ LEG+ +A E Y+KA + PEN E LT L L L + Sbjct: 159 HNALNLNRHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQL 215 >gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo sapiens] Length = 807 Score = 39.7 bits (91), Expect = 0.006 Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 17/138 (12%) Query: 266 NKALELLKKALEVTPTSSFLHHQMGLCYRAQ--------MIQIKKATHNRP-----KGKD 312 N+A+ L KA+++ P++ H+ L + ++ Q + N+P KG Sbjct: 180 NEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLT 239 Query: 313 KLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEN--- 369 L+ AI FK A+++ F AY L Y E G + A + F+KAL L Sbjct: 240 FFHRG-LLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHV 298 Query: 370 ITDDHKHQIHYHYGRFQE 387 T + + YH+G QE Sbjct: 299 QTLQLRGMMLYHHGSLQE 316 >gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] Length = 1564 Score = 38.1 bits (87), Expect = 0.018 Identities = 37/151 (24%), Positives = 63/151 (41%), Gaps = 32/151 (21%) Query: 340 AYTDLANMYAEGG-------QYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKS 392 +Y DLA ++A Y AE F++AL + ++ +Q+ Y E RK Sbjct: 415 SYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKD 474 Query: 393 ENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYK-LEGEK 451 + A+ H+L+A + L K C+ LG Y+ + G+K Sbjct: 475 KTKALTHFLKAAR--------------LDTYMGKVFCY----------LGHYYRDVVGDK 510 Query: 452 RQAAEYYEKAQKIDPENAEFLTALCELRLSI 482 +A Y KA ++D +AE A +L + + Sbjct: 511 NRARGCYRKAFELDDTDAESGAAAVDLSVEL 541 Score = 34.7 bits (78), Expect = 0.20 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 17/138 (12%) Query: 233 EGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLC 292 E K +E++L V A + K + +A + ++ALE + H+Q+GL Sbjct: 404 EAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLT 463 Query: 293 YRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAE-G 351 Y + + KDK K A+ HF A D+ + L + Y + Sbjct: 464 YWFMGEETR---------KDKTK-------ALTHFLKAARLDTYMGKVFCYLGHYYRDVV 507 Query: 352 GQYSNAEDIFRKALRLEN 369 G + A +RKA L++ Sbjct: 508 GDKNRARGCYRKAFELDD 525 >gi|189011544 ubiquitously transcribed tetratricopeptide repeat, X chromosome [Homo sapiens] Length = 1401 Score = 35.0 bits (79), Expect = 0.15 Identities = 55/260 (21%), Positives = 104/260 (40%), Gaps = 40/260 (15%) Query: 145 GWALLKFGGKYYQKAKAAFEKALEVEPD-----NPEFNIGYAITVYRLDDSDREGSVKSF 199 G L+ F +Q A AF++ L V+P +G V ++D E S+K F Sbjct: 135 GLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKV----NTDYESSLKHF 190 Query: 200 SLGPLRKAVTLNP---DNSYIKVFLALKLQDVHAEAEGEKYIEEIL--DQISSQ--PYVL 252 L V NP N+ I+ +A + ++ E++L + +S+Q VL Sbjct: 191 QLA----LVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVKATVL 246 Query: 253 RYAAKFYR-------RKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRA-QMIQIKKAT 304 + + + + A++ L+K+LE P S + +G CY + +Q + Sbjct: 247 QQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFIS 306 Query: 305 HNRPKGKDKLKVDELISSAIFH------------FKAAMERDSMFAFAYTDLANMYAEGG 352 + + K + D S + + + A++ D A A+ DL +Y Sbjct: 307 YRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCN 366 Query: 353 QYSNAEDIFRKALRLENITD 372 Q +A + A R ++ ++ Sbjct: 367 QPQDAIKCYLNATRSKSCSN 386 >gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] Length = 2481 Score = 34.7 bits (78), Expect = 0.20 Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 19/129 (14%) Query: 340 AYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRK-SENTAIH 398 AY ++ N Y G Y A R+ L++ +D Q H + + + A+ Sbjct: 516 AYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQ 575 Query: 399 HYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYY 458 HY L + + L + ++LS LG + GE QAA YY Sbjct: 576 HYQNHLNI------------------ARELRDIQSEARALSNLGNFHCSRGEYVQAAPYY 617 Query: 459 EKAQKIDPE 467 E+ ++ P+ Sbjct: 618 EQYLRLAPD 626 >gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapiens] Length = 830 Score = 34.3 bits (77), Expect = 0.26 Identities = 50/243 (20%), Positives = 99/243 (40%), Gaps = 40/243 (16%) Query: 239 EEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMI 298 +++ D + P A + + + A++ ++A++V P ++ + +G Sbjct: 563 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG-------- 614 Query: 299 QIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAE 358 + + E + A+ F+ A+ + A+ L +Y + ++S AE Sbjct: 615 -------------HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 661 Query: 359 DIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPL------ 412 F+KAL + + + H G Q +KSE A+ +A+ + ++PL Sbjct: 662 MHFQKALDI----NPQSSVLLCHIGVVQHALKKSEK-ALDTLNKAIVIDPKNPLCKFHRA 716 Query: 413 -----RTKLTSALKKLST-KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDP 466 K SAL++L K++ V L +G VYK G+ A + A +DP Sbjct: 717 SVLFANEKYKSALQELEELKQIVPKESLVYFL--IGKVYKKLGQTHLALMNFSWAMDLDP 774 Query: 467 ENA 469 + A Sbjct: 775 KGA 777 >gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapiens] Length = 824 Score = 34.3 bits (77), Expect = 0.26 Identities = 50/243 (20%), Positives = 99/243 (40%), Gaps = 40/243 (16%) Query: 239 EEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMI 298 +++ D + P A + + + A++ ++A++V P ++ + +G Sbjct: 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG-------- 608 Query: 299 QIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAE 358 + + E + A+ F+ A+ + A+ L +Y + ++S AE Sbjct: 609 -------------HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655 Query: 359 DIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPL------ 412 F+KAL + + + H G Q +KSE A+ +A+ + ++PL Sbjct: 656 MHFQKALDI----NPQSSVLLCHIGVVQHALKKSEK-ALDTLNKAIVIDPKNPLCKFHRA 710 Query: 413 -----RTKLTSALKKLST-KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDP 466 K SAL++L K++ V L +G VYK G+ A + A +DP Sbjct: 711 SVLFANEKYKSALQELEELKQIVPKESLVYFL--IGKVYKKLGQTHLALMNFSWAMDLDP 768 Query: 467 ENA 469 + A Sbjct: 769 KGA 771 >gi|239741018 PREDICTED: hypothetical protein XP_002342056 [Homo sapiens] Length = 566 Score = 33.5 bits (75), Expect = 0.44 Identities = 57/215 (26%), Positives = 87/215 (40%), Gaps = 34/215 (15%) Query: 163 FEKALEVEPDNPEFNIGYAITVYRLDDSDR--EGSVKSFSLGP---LRKAVTLNPDN--- 214 F L EP N + G A+ LD + V + LGP + + +L P+ Sbjct: 201 FNTVLRAEPGNVQALCGRALVHLALDQLQEAVDDIVSALKLGPGTVVPELRSLKPEAQAL 260 Query: 215 ------SYIKVFLALKLQDVHA-----EAEGEKYIEEILDQISS-QPYVLRYAAKFYRRK 262 S+ + L+ +L D A + +G + E L +I S QP+ A + Sbjct: 261 ITQGLYSHCRALLS-QLPDTGAPLEDKDTQGLLAVGEALIKIDSGQPHWHLLLADILMAQ 319 Query: 263 NSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKL----KVDE 318 S+ +A L+KAL PTS ++GL +Q+KK + P L +VD Sbjct: 320 GSYEEAGTHLEKALHRAPTSEAARARLGL------LQLKKG--DVPGAARDLQSLAEVDA 371 Query: 319 LISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQ 353 S + H A ER S+ A A A + GQ Sbjct: 372 PDLSCLLHLLEASERQSL-AQAAAQEAGTLLDAGQ 405 >gi|4557269 adenylosuccinate lyase isoform a [Homo sapiens] Length = 484 Score = 33.1 bits (74), Expect = 0.58 Identities = 22/109 (20%), Positives = 48/109 (44%), Gaps = 10/109 (9%) Query: 34 VEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNKDALECL----EQAEEIIQQEHSDKE 89 +E I Q+L F+ T+ N++ + G +D E + +QA +++QE D + Sbjct: 369 IERRIRQELPFMATE------NIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDND 422 Query: 90 EVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECP 138 + + ++ ++ +D L + +TG+ ++ Y L P Sbjct: 423 LIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKP 471 >gi|54607135 translocase of outer mitochondrial membrane 70 homolog A [Homo sapiens] Length = 608 Score = 33.1 bits (74), Expect = 0.58 Identities = 44/200 (22%), Positives = 78/200 (39%), Gaps = 24/200 (12%) Query: 103 VYYH-------MDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLK--FGG 153 VY+H +DQ+EEA + C +L + E +K +AL + + G Sbjct: 403 VYHHRGQLKILLDQVEEAVADFDE----CIRL------RPESALAQAQKCFALYRQAYTG 452 Query: 154 KYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPD 213 + +AA + EV P GYA+ L D + G K + L PD Sbjct: 453 NNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEM----YDKCIDLEPD 508 Query: 214 NSYIKVFLAL-KLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELL 272 N+ V L +LQ G + I + ++ + + ++ + KA+++ Sbjct: 509 NATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMF 568 Query: 273 KKALEVTPTSSFLHHQMGLC 292 KA+ + + + H LC Sbjct: 569 NKAINLAKSEMEMAHLYSLC 588 Score = 32.3 bits (72), Expect = 0.98 Identities = 51/236 (21%), Positives = 90/236 (38%), Gaps = 45/236 (19%) Query: 147 ALLKFGGKYYQKAKAA-----FEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSL 201 AL+K G Y Q+ + F A +++P N + LD E +V F Sbjct: 369 ALIKRGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQV--EEAVADFD- 425 Query: 202 GPLRKAVTLNPDNS----------YIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYV 251 + + L P+++ Y + + + A +G EE++ + Sbjct: 426 ----ECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKG---FEEVIKKFPRCAEG 478 Query: 252 LRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGK 311 A+ + + KA E+ K +++ P ++ + GL +Q K+ Sbjct: 479 YALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLL----QLQWKQ--------- 525 Query: 312 DKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367 D + ELIS AI E D+ FAY + + + G A D+F KA+ L Sbjct: 526 DLDRGLELISKAI-------EIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINL 574 >gi|22749211 transmembrane and tetratricopeptide repeat containing 2 [Homo sapiens] Length = 836 Score = 33.1 bits (74), Expect = 0.58 Identities = 50/248 (20%), Positives = 95/248 (38%), Gaps = 34/248 (13%) Query: 251 VLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHN---- 306 ++ Y K R W L + ++V P ++ + L ++++ + + A N Sbjct: 463 IVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGNVLKSQSKISEAESAYRNALYY 522 Query: 307 RPKGKDKL-------KVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAED 359 R D L + + + A+ ++K A+ A AY + + G+ A Sbjct: 523 RSNMADMLYNLGLLLQENSRFAEALHYYKLAIGSRPTLASAYLNTGIILMNQGRTEEARR 582 Query: 360 IFRKALRL--ENITDDHKHQIH-----YHYGRFQEFHRKSE-NTAIHHYLEALKVKDRS- 410 F K + EN+ D H H+ Y+ G+ +H + A+ Y EA++ R Sbjct: 583 TFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKL--YHEQGHYEEALSVYKEAIQKMPRQF 640 Query: 411 ---PLRTKLTSALKKLST---------KRLCHNALDVQSLSALGFVYKLEGEKRQAAEYY 458 L + A +LS + L + + G + L G K +A + + Sbjct: 641 APQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEAEKLF 700 Query: 459 EKAQKIDP 466 KA ++DP Sbjct: 701 LKAIELDP 708 >gi|144446030 lymphocyte antigen 75 [Homo sapiens] Length = 1722 Score = 33.1 bits (74), Expect = 0.58 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 6/84 (7%) Query: 309 KGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE 368 K ++L++ SSA+ +K E S++ A LA G SNA D+++K E Sbjct: 90 KSVNELRMFSCDSSAMLWWKC--EHHSLYGAARYRLALKDGHGTAISNASDVWKKGGSEE 147 Query: 369 NITDDHKHQIHYH----YGRFQEF 388 ++ D H+I+ YGR EF Sbjct: 148 SLCDQPYHEIYTRDGNSYGRPCEF 171 >gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo sapiens] Length = 631 Score = 32.3 bits (72), Expect = 0.98 Identities = 40/208 (19%), Positives = 86/208 (41%), Gaps = 30/208 (14%) Query: 83 QEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDC 142 +E + K ++S + AW +D++ + K + + LS S + + D Sbjct: 77 REENTKNRIKS---YDYEAWAKLDVDRILDE---LDKDDSTHESLSQESESEEDGIHVDS 130 Query: 143 EKGWALLKFGGKYYQKAKA-----AFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVK 197 +K L + G KY+++ K + K ++ +P NP A +RL K Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL---------K 181 Query: 198 SFSLGPLRKAVTLNPDNSYIKV--------FLALKLQDVHAEAEGEKYIEEILDQISSQP 249 F++ + + + SY K F KL++ A+ + E+ +E + + Sbjct: 182 KFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE--AKKDYERVLELEPNNFEATN 239 Query: 250 YVLRYAAKFYRRKNSWNKALELLKKALE 277 + + + ++NS+ K +++ K+ E Sbjct: 240 ELRKISQALASKENSYPKEADIVIKSTE 267 Score = 29.6 bits (65), Expect = 6.4 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 33/159 (20%) Query: 47 TKSRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQE--------HSDKEEVRSLVTWG 98 TK+R+ Y+ A+ K + D L+ + E + QE H D ++ L G Sbjct: 81 TKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKG 140 Query: 99 NYAWVYYHMDQLEEA-QKYTGKIG----NVCKKLSSPSNY----KLECPETDCEKGWALL 149 N Y+ + +EA YT + N + S Y K E+DC AL Sbjct: 141 NK---YFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALN 197 Query: 150 KFGGKYY-------------QKAKAAFEKALEVEPDNPE 175 + K Y ++AK +E+ LE+EP+N E Sbjct: 198 RSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFE 236 >gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo sapiens] Length = 665 Score = 32.3 bits (72), Expect = 0.98 Identities = 40/208 (19%), Positives = 86/208 (41%), Gaps = 30/208 (14%) Query: 83 QEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDC 142 +E + K ++S + AW +D++ + K + + LS S + + D Sbjct: 77 REENTKNRIKS---YDYEAWAKLDVDRILDE---LDKDDSTHESLSQESESEEDGIHVDS 130 Query: 143 EKGWALLKFGGKYYQKAKA-----AFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVK 197 +K L + G KY+++ K + K ++ +P NP A +RL K Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL---------K 181 Query: 198 SFSLGPLRKAVTLNPDNSYIKV--------FLALKLQDVHAEAEGEKYIEEILDQISSQP 249 F++ + + + SY K F KL++ A+ + E+ +E + + Sbjct: 182 KFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEE--AKKDYERVLELEPNNFEATN 239 Query: 250 YVLRYAAKFYRRKNSWNKALELLKKALE 277 + + + ++NS+ K +++ K+ E Sbjct: 240 ELRKISQALASKENSYPKEADIVIKSTE 267 Score = 29.6 bits (65), Expect = 6.4 Identities = 41/159 (25%), Positives = 64/159 (40%), Gaps = 33/159 (20%) Query: 47 TKSRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQE--------HSDKEEVRSLVTWG 98 TK+R+ Y+ A+ K + D L+ + E + QE H D ++ L G Sbjct: 81 TKNRIKSYDYEAWAKLDVDRILDELDKDDSTHESLSQESESEEDGIHVDSQKALVLKEKG 140 Query: 99 NYAWVYYHMDQLEEA-QKYTGKIG----NVCKKLSSPSNY----KLECPETDCEKGWALL 149 N Y+ + +EA YT + N + S Y K E+DC AL Sbjct: 141 NK---YFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALN 197 Query: 150 KFGGKYY-------------QKAKAAFEKALEVEPDNPE 175 + K Y ++AK +E+ LE+EP+N E Sbjct: 198 RSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFE 236 >gi|52630440 FK506-binding protein 8 [Homo sapiens] Length = 413 Score = 32.0 bits (71), Expect = 1.3 Identities = 39/165 (23%), Positives = 64/165 (38%), Gaps = 29/165 (17%) Query: 256 AKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLK 315 A F NS++ A++ + + +V T AQ++Q+K N +LK Sbjct: 236 ADFVLAANSYDLAIKAITSSAKVDMTFE---------EEAQLLQLKVKCLNN-LAASQLK 285 Query: 316 VDELISSAIFHFKAAMERDSMFAFAYTD-------LANMYAEGGQYSNAEDIFRKALRLE 368 +D H++AA+ S+ D + A+ G+YS A I R AL+LE Sbjct: 286 LD--------HYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLE 337 Query: 369 NITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLR 413 IH + + H +T Y + L R P + Sbjct: 338 ----PSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAK 378 >gi|28603842 tetratricopeptide repeat domain 9C [Homo sapiens] Length = 171 Score = 32.0 bits (71), Expect = 1.3 Identities = 25/106 (23%), Positives = 45/106 (42%), Gaps = 9/106 (8%) Query: 135 LECPETDCEKGWA--LLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDR 192 L +TDC A LL+ Y++ + +K LE +PDN + + + L D D+ Sbjct: 67 LHTTQTDCYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDQ 126 Query: 193 EGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYI 238 L AV P ++ ++ +L L ++ + EK + Sbjct: 127 ARHY-------LLAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQL 165 >gi|118766328 transmembrane and tetratricopeptide repeat containing 4 isoform 2 [Homo sapiens] Length = 741 Score = 32.0 bits (71), Expect = 1.3 Identities = 21/108 (19%), Positives = 46/108 (42%), Gaps = 21/108 (19%) Query: 261 RKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELI 320 R W +L + AL V P ++ +H+ +G + KG Sbjct: 460 RSGEWRSEEQLFRSALSVCPLNAKVHYNIG-------------KNLADKGNQ-------- 498 Query: 321 SSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE 368 ++AI +++ A+ + + A +L N+ E + AE++ A++++ Sbjct: 499 TAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQ 546 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.133 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,779,039 Number of Sequences: 37866 Number of extensions: 698736 Number of successful extensions: 2398 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 45 Number of HSP's that attempted gapping in prelim test: 2226 Number of HSP's gapped (non-prelim): 164 length of query: 482 length of database: 18,247,518 effective HSP length: 106 effective length of query: 376 effective length of database: 14,233,722 effective search space: 5351879472 effective search space used: 5351879472 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.