Search of human proteins with 6912604

Search of human proteins with 6912604

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
         (234 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]           473   e-134
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   388   e-108
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   261   4e-70
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...   235   2e-62
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...   211   6e-55
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...   211   6e-55
gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]          195   3e-50
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...   184   4e-47
gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]          162   3e-40
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...   160   1e-39
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    69   3e-12
gi|21735415 centromere protein B [Homo sapiens]                        61   9e-10
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          59   5e-09
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           59   5e-09
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           59   5e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    58   6e-09
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    57   1e-08
gi|17975763 myelin transcription factor 1 [Homo sapiens]               55   4e-08
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]     54   1e-07
gi|28274705 family with sequence similarity 9, member A [Homo sa...    54   1e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               52   3e-07
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       52   3e-07
gi|221219020 NYD-SP11 protein [Homo sapiens]                           52   6e-07
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]     52   6e-07
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]     52   6e-07
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              52   6e-07
gi|66472382 nischarin [Homo sapiens]                                   52   6e-07
gi|55956788 nucleolin [Homo sapiens]                                   51   7e-07
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     51   7e-07
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     51   7e-07

>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
          Length = 234

 Score =  473 bits (1216), Expect = e-134
 Identities = 234/234 (100%), Positives = 234/234 (100%)

Query: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60
           MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL
Sbjct: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60

Query: 61  PKLKLRKLELRVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNCE 120
           PKLKLRKLELRVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNCE
Sbjct: 61  PKLKLRKLELRVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNCE 120

Query: 121 VTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQ 180
           VTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQ
Sbjct: 121 VTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQ 180

Query: 181 VVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234
           VVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK
Sbjct: 181 VVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score =  388 bits (997), Expect = e-108
 Identities = 205/238 (86%), Positives = 212/238 (89%), Gaps = 4/238 (1%)

Query: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60
           MEMGRRIH ELRNR PSDVKEL LDNSRSNEGKLE LTDEFEELEFLS IN GLTSI++L
Sbjct: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60

Query: 61  PKL-KLRKLEL---RVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL 116
           PKL KL+KLEL   RVSGGLEVLAEKCPNLTHL LSGNKIKDLSTIEPLK+LENLKSLDL
Sbjct: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120

Query: 117 FNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYD 176
           FNCEVTNLNDY ENVFKLL QLTYLD    D KEAP SD E +VEGLDDEEE E EEEYD
Sbjct: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD 180

Query: 177 EDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234
           EDAQVVEDEE E+EEEEGEEEDVSG +EEDEEGYNDGEVD EEDEEELGEEERGQKRK
Sbjct: 181 EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRK 238


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score =  261 bits (667), Expect = 4e-70
 Identities = 148/244 (60%), Positives = 186/244 (76%), Gaps = 13/244 (5%)

Query: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60
           M+M RRIH ELRNR P+ V+EL LDN +SN+GK+E LT EF  LEFLS IN GL S+S+L
Sbjct: 1   MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNL 60

Query: 61  PKL-KLRKLEL---RVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL 116
           PKL KL+KLEL   R+ GGL++LAEK PNLTHL LSGNK+KD+ST+EPLK+LE LKSLDL
Sbjct: 61  PKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDL 120

Query: 117 FNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEH-EEEY 175
           FNCEVTNLNDY E+VFKLL QLTYLD    + +EAP SD E  V+G+D+EEE E  E+E 
Sbjct: 121 FNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAE--VDGVDEEEEDEEGEDEE 178

Query: 176 DEDAQVVEDEEGEEEEE-----EGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERG 230
           DED +  E+EE +EE++     EG+E+D    +EE+E G ++ + D +EDEEE  E  +G
Sbjct: 179 DEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEE-EEGGKG 237

Query: 231 QKRK 234
           +KRK
Sbjct: 238 EKRK 241


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score =  235 bits (600), Expect = 2e-62
 Identities = 139/256 (54%), Positives = 175/256 (68%), Gaps = 22/256 (8%)

Query: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60
           MEM ++I+ ELRNR+P +V EL LDN     G++E L D F+ELEFLS  N  L+S++ L
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60

Query: 61  PKL-KLRKLELR---VSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL 116
           P L KLRKLEL    +SGGLEVLAEKCPNLT+L LSGNKIKDLST+E L+ L+NLKSLDL
Sbjct: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120

Query: 117 FNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEG-LDDEEEGEHEEEY 175
           FNCE+TNL DY E++F+LL Q+TYLD    +  EAP S+ ED  +G  DDEEE E+E   
Sbjct: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180

Query: 176 DEDAQVVEDEEGEEEEEEGEEEDVSG-----GDEE------------DEEGYNDGEVDGE 218
            E  +  E+EE EE+E+E E+ED +G     G+EE            DEE  +D   +GE
Sbjct: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240

Query: 219 EDEEELGEEERGQKRK 234
           E+EEE     RG+KRK
Sbjct: 241 EEEEEEEGGLRGEKRK 256



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 155 DIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEED 198
           +I+D  +  D  EEGE EEE +E+  +  ++   + E++GEEED
Sbjct: 225 EIQDEEDDDDYVEEGEEEEE-EEEGGLRGEKRKRDAEDDGEEED 267


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  211 bits (536), Expect = 6e-55
 Identities = 130/231 (56%), Positives = 161/231 (69%), Gaps = 21/231 (9%)

Query: 19  VKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDLPKL-KLRKLEL---RVSG 74
           V+E  LDN +SN+ K+E+LT EF  LEFL  IN GL SIS+LPKL KL+K  L   R+ G
Sbjct: 39  VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98

Query: 75  GLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNCEVTNLNDYGENVFKL 134
           GL + AEK PNLTHL LSG K+KD+ST+EPLK+LE LKSLDLFNCEV NLNDY E+VFKL
Sbjct: 99  GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQESVFKL 158

Query: 135 LLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEE---E 191
           L QLT LD+   + +EAP SD +  V+G+D EE    E+E  ED +  E+E+GEEE   E
Sbjct: 159 LPQLTCLDTYDPEDQEAPDSDAQ--VDGVDKEE----EDEEGEDEKDXENEDGEEEELDE 212

Query: 192 EEGEEEDVSGGD-------EEDEEGYNDGEVDGEEDEEELGEEE-RGQKRK 234
           EE E+EDV G D       EE+E G +  E D +EDE+E  EE  +G+ RK
Sbjct: 213 EEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRK 263


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  211 bits (536), Expect = 6e-55
 Identities = 130/231 (56%), Positives = 161/231 (69%), Gaps = 21/231 (9%)

Query: 19  VKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDLPKL-KLRKLEL---RVSG 74
           V+E  LDN +SN+ K+E+LT EF  LEFL  IN GL SIS+LPKL KL+K  L   R+ G
Sbjct: 39  VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98

Query: 75  GLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNCEVTNLNDYGENVFKL 134
           GL + AEK PNLTHL LSG K+KD+ST+EPLK+LE LKSLDLFNCEV NLNDY E+VFKL
Sbjct: 99  GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQESVFKL 158

Query: 135 LLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEE---E 191
           L QLT LD+   + +EAP SD +  V+G+D EE    E+E  ED +  E+E+GEEE   E
Sbjct: 159 LPQLTCLDTYDPEDQEAPDSDAQ--VDGVDKEE----EDEEGEDEKDXENEDGEEEELDE 212

Query: 192 EEGEEEDVSGGD-------EEDEEGYNDGEVDGEEDEEELGEEE-RGQKRK 234
           EE E+EDV G D       EE+E G +  E D +EDE+E  EE  +G+ RK
Sbjct: 213 EEDEDEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRK 263


>gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]
          Length = 131

 Score =  195 bits (495), Expect = 3e-50
 Identities = 105/131 (80%), Positives = 114/131 (87%), Gaps = 4/131 (3%)

Query: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60
           MEMG+ IH ELRNR PSDVKEL LDNS+SNEGKLE LTDEFEELE L+ IN GLTSI++L
Sbjct: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60

Query: 61  PKL-KLRKLEL---RVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL 116
           PKL KL+KLEL   R S GLEVLAEKCPNL HL LSGNKIKDLSTIEPLK+LENL+SLDL
Sbjct: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120

Query: 117 FNCEVTNLNDY 127
           F CEVTNLN+Y
Sbjct: 121 FTCEVTNLNNY 131


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score =  184 bits (468), Expect = 4e-47
 Identities = 112/206 (54%), Positives = 140/206 (67%), Gaps = 22/206 (10%)

Query: 51  NGGLTSISDLPKL-KLRKLELR---VSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLK 106
           N  L+S++ LP L KLRKLEL    +SGGLEVLAEKCPNLT+L LSGNKIKDLST+E L+
Sbjct: 3   NVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQ 62

Query: 107 QLENLKSLDLFNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEG-LDD 165
            L+NLKSLDLFNCE+TNL DY E++F+LL Q+TYLD    +  EAP S+ ED  +G  DD
Sbjct: 63  NLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDD 122

Query: 166 EEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSG-----GDEE------------DEE 208
           EEE E+E    E  +  E+EE EE+E+E E+ED +G     G+EE            DEE
Sbjct: 123 EEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEE 182

Query: 209 GYNDGEVDGEEDEEELGEEERGQKRK 234
             +D   +GEE+EEE     RG+KRK
Sbjct: 183 DDDDYVEEGEEEEEEEEGGLRGEKRK 208



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 155 DIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEED 198
           +I+D  +  D  EEGE EEE +E+  +  ++   + E++GEEED
Sbjct: 177 EIQDEEDDDDYVEEGEEEEE-EEEGGLRGEKRKRDAEDDGEEED 219


>gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]
          Length = 450

 Score =  162 bits (409), Expect = 3e-40
 Identities = 91/143 (63%), Positives = 109/143 (76%), Gaps = 4/143 (2%)

Query: 19  VKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDLPKL-KLRKLEL---RVSG 74
           V+E  LDN +SN+ K+E+LT EF  LEFL  IN GL SIS+LPKL KL+K  L   R+ G
Sbjct: 39  VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98

Query: 75  GLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNCEVTNLNDYGENVFKL 134
           GL + AEK PNLTHL LSG K+KD+ST+EPLK+LE LKSLDLFNCEV NLNDY E+VFKL
Sbjct: 99  GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQESVFKL 158

Query: 135 LLQLTYLDSCYWDHKEAPYSDIE 157
           L QLT LD+   + +EAP SD +
Sbjct: 159 LPQLTCLDTYDPEDQEAPDSDAQ 181


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score =  160 bits (404), Expect = 1e-39
 Identities = 107/253 (42%), Positives = 140/253 (55%), Gaps = 57/253 (22%)

Query: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60
           MEM ++I+ ELRNR+P +V EL LDN     G++E L D F+ELEFLS  N  L+S++ L
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60

Query: 61  PKL-KLRKLELRVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNC 119
           P L KLRK                                      + L+NLKSLDLFNC
Sbjct: 61  PSLNKLRK--------------------------------------QNLKNLKSLDLFNC 82

Query: 120 EVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEG-LDDEEEGEHEEEYDED 178
           E+TNL DY E++F+LL Q+TYLD    +  EAP S+ ED  +G  DDEEE E+E    E 
Sbjct: 83  EITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG 142

Query: 179 AQVVEDEEGEEEEEEGEEEDVSG-----GDEE------------DEEGYNDGEVDGEEDE 221
            +  E+EE EE+E+E E+ED +G     G+EE            DEE  +D   +GEE+E
Sbjct: 143 YEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEE 202

Query: 222 EELGEEERGQKRK 234
           EE     RG+KRK
Sbjct: 203 EEEEGGLRGEKRK 215



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 155 DIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEED 198
           +I+D  +  D  EEGE EEE +E+  +  ++   + E++GEEED
Sbjct: 184 EIQDEEDDDDYVEEGEEEEE-EEEGGLRGEKRKRDAEDDGEEED 226


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 45/89 (50%), Positives = 57/89 (64%), Gaps = 4/89 (4%)

Query: 146  WDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEE-EEEGE-EEDVSGGD 203
            W+ +E    + E   EG  + EEGE E E +E     E+EEGEEE EEEGE EE+  G  
Sbjct: 955  WEGEEEE-GEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEG 1013

Query: 204  EEDEEGYNDGEVDGEEDEEELGEEERGQK 232
            EE+EEG  +GEV+GEE E E GEEE G++
Sbjct: 1014 EEEEEGEVEGEVEGEEGEGE-GEEEEGEE 1041



 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 42/74 (56%), Positives = 51/74 (68%), Gaps = 5/74 (6%)

Query: 160 VEGLDDEE-EGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSG-GDEEDEEGYNDGEVDG 217
           VEG + EE +GE EEE +E     E+ EGEEEE EGEEE+  G G+EE EEG  +GE +G
Sbjct: 814 VEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG--EGEEEG 871

Query: 218 EEDEEELGEEERGQ 231
           EE E E GEEE G+
Sbjct: 872 EEGEGE-GEEEEGE 884



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 38/74 (51%), Positives = 47/74 (63%), Gaps = 4/74 (5%)

Query: 161 EGLDDEEEGEHEEEYDEDAQVVEDE---EGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDG 217
           EG ++ EEGE E E +E     E+E   EGEEEE EGE E+   G+ E+EEG   GE +G
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG 925

Query: 218 EEDEEELGEEERGQ 231
           EE E E GEEE G+
Sbjct: 926 EEGEGE-GEEEEGE 938



 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 40/80 (50%), Positives = 47/80 (58%), Gaps = 9/80 (11%)

Query: 161 EGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEE------EGEEEDVSGGDEEDEEG---YN 211
           EG  +EEEGE EEE  E     E EEGE EEE      EGEEE+  G  EE+ EG     
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEE 898

Query: 212 DGEVDGEEDEEELGEEERGQ 231
           +GE +GEE+ E  GEEE G+
Sbjct: 899 EGEGEGEEEGEGEGEEEEGE 918



 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 40/84 (47%), Positives = 52/84 (61%), Gaps = 8/84 (9%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGE----EEEEEGEEEDVSGGDEEDEEGYND 212
           E+  EG ++E EG+ EEE +E     E EEGE    EEE EGE E+   G+ E+EEG  +
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903

Query: 213 GEVDGE-EDEEELGE---EERGQK 232
           GE +GE E EEE GE   EE G++
Sbjct: 904 GEEEGEGEGEEEEGEGKGEEEGEE 927



 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 37/76 (48%), Positives = 48/76 (63%), Gaps = 3/76 (3%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGE-EEDVSGGDEEDEEGYNDGEV 215
           E+  EG  +EEEGE EEE  E  +   + +GEEE EEGE EE+   G+ E EE   +GE 
Sbjct: 828 EEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE--EEGEG 885

Query: 216 DGEEDEEELGEEERGQ 231
           +GEE+ E  GEEE G+
Sbjct: 886 EGEEEGEGEGEEEEGE 901



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 39/83 (46%), Positives = 49/83 (59%), Gaps = 11/83 (13%)

Query: 157 EDHVEGLDDEEE-------GEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEG 209
           E+  EG  +E+E       GE EE   E  +  E+ EGEEEE EGEEE+   G+ E+EEG
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE---GEGEEEEG 854

Query: 210 YNDGEVDGEEDE-EELGEEERGQ 231
              GE +GEE E EE GEE  G+
Sbjct: 855 EGKGEEEGEEGEGEEEGEEGEGE 877



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 35/76 (46%), Positives = 47/76 (61%), Gaps = 1/76 (1%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD 216
           E+  EG  +EEEGE E E + + +  E+E   + EEEGEE +  G +EE E    DGE +
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947

Query: 217 GEEDEEEL-GEEERGQ 231
           GEE+E E  GEEE G+
Sbjct: 948 GEEEEGEWEGEEEEGE 963



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 37/76 (48%), Positives = 49/76 (64%), Gaps = 5/76 (6%)

Query: 161  EGLDDEEEGEHEEEYDE-DAQVVEDEEGEEEEEEGEEEDVSG-GDEEDEEGYNDGEVDGE 218
            EG  +EEEGE E E +E + +  E+ EGE EE EGE E+  G G+ E+EEG  +GE +GE
Sbjct: 945  EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004

Query: 219  EDEEELG---EEERGQ 231
             +EE  G   EEE G+
Sbjct: 1005 GEEEGEGEGEEEEEGE 1020



 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 38/89 (42%), Positives = 51/89 (57%), Gaps = 4/89 (4%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGE---EEEEEGEEEDVSGGD 203
           + +E    + E   +G ++ EEGE EEE +E     E+EEGE   EEE EGE E+  G  
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 902

Query: 204 EEDEEGYNDGEVD-GEEDEEELGEEERGQ 231
           E +EEG  +GE + GE   EE GEE  G+
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEGEEGEGE 931



 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 37/86 (43%), Positives = 49/86 (56%), Gaps = 2/86 (2%)

Query: 147  DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED 206
            + +E  +   E+  EG + EEEGE E E  E     E+ EGE EEEEGEEE    G+ E+
Sbjct: 949  EEEEGEWEGEEEEGEG-EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007

Query: 207  E-EGYNDGEVDGEEDEEELGEEERGQ 231
            E EG  + E +GE + E  GEE  G+
Sbjct: 1008 EGEGEGEEEEEGEVEGEVEGEEGEGE 1033



 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 41/101 (40%), Positives = 55/101 (54%), Gaps = 19/101 (18%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDE---DAQVVEDEEGEEE--EEEGEEEDVSG 201
           D +E    + E   EG  +E EGE E+E  E   + +  ++E+GEEE  + EGEEE+  G
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803

Query: 202 GDEEDEEGYNDGEVDG-----------EEDEEELGEEERGQ 231
             EE EEG   GEV+G           EE+EE  GEEE G+
Sbjct: 804 RGEEKEEG---GEVEGGEVEEGKGEREEEEEEGEGEEEEGE 841



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 38/91 (41%), Positives = 51/91 (56%), Gaps = 16/91 (17%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVE-----DEEGEEEEEEGEEEDVSG------GDEE 205
           E   EG ++E EGE EEE + + +  E     +EEGEE E EGEEE+  G      G+ E
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGE 949

Query: 206 DEEG-----YNDGEVDGEEDEEELGEEERGQ 231
           +EEG       +GE +GEE+ E  GEE  G+
Sbjct: 950 EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE 980



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 37/70 (52%), Positives = 42/70 (60%), Gaps = 2/70 (2%)

Query: 161 EGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD-GE- 218
           EG  +EEEGE E E  E     E+ E E EEEEGE E    G+ E EEG  +GE + GE 
Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988

Query: 219 EDEEELGEEE 228
           E EEE GEEE
Sbjct: 989 EGEEEEGEEE 998



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 38/75 (50%), Positives = 48/75 (64%), Gaps = 4/75 (5%)

Query: 161  EGLDDEEEGEHEEEYDEDAQVVEDEEGE-EEEEEGEEEDVSG-GDEEDEEGYNDG-EVDG 217
            EG  + E+GE E E +E     E+EEGE E EEEGE E   G G+ E+EEG  +G E +G
Sbjct: 936  EGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEG 995

Query: 218  EEDEEELGE-EERGQ 231
            EE+ EE GE EE G+
Sbjct: 996  EEEGEEEGEGEEEGE 1010



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 37/80 (46%), Positives = 51/80 (63%), Gaps = 8/80 (10%)

Query: 157  EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGE-EEEEEGEEEDVSGGDEEDEEGYNDG-E 214
            E+  EG  +EEEGE  EE +E+ +  E+ EGE EEEEEGE E    G+ E EEG  +G E
Sbjct: 983  EEEGEGEGEEEEGE--EEGEEEGEGEEEGEGEGEEEEEGEVE----GEVEGEEGEGEGEE 1036

Query: 215  VDGEEDEEELGEEERGQKRK 234
             +GEE+ EE  +E  G++ +
Sbjct: 1037 EEGEEEGEEREKEGEGEENR 1056



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 40/84 (47%), Positives = 50/84 (59%), Gaps = 8/84 (9%)

Query: 157 EDHVEGLDDEE----EGEHEEEYDEDAQVVEDEEGEEEEE--EGEEEDVSGGDEEDEEGY 210
           E+  EG  +EE    EGE EEE  E      + EGEEEE   EGEEE+  G  EE+ EG 
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973

Query: 211 -NDGEVDGEEDE-EELGEEERGQK 232
             +GE +GEE+E E  GEEE G++
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEEGEE 997



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 33/75 (44%), Positives = 44/75 (58%), Gaps = 3/75 (4%)

Query: 157  EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD 216
            E+  E  + EEEGE E E +E+ +V  + EGEE E EGEEE+   G+EE EE   +GE +
Sbjct: 997  EEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE---GEEEGEEREKEGEGE 1053

Query: 217  GEEDEEELGEEERGQ 231
                  E  EEE G+
Sbjct: 1054 ENRRNREEEEEEEGK 1068



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 27/71 (38%), Positives = 45/71 (63%), Gaps = 1/71 (1%)

Query: 164 DDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEE 223
           +++E+ E E+ + ++     +E GEEE  EGEEE+    +EE++EG    E +GEE E E
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGE 767

Query: 224 LGEEERGQKRK 234
             E+E G+++K
Sbjct: 768 -REKEEGERKK 777



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 29/88 (32%), Positives = 47/88 (53%), Gaps = 1/88 (1%)

Query: 146 WDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGE-EEEEEGEEEDVSGGDE 204
           W  ++    + ++  +G   E   E EE  +E+    E+EEG+ EEEEE E E    G+ 
Sbjct: 702 WKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEG 761

Query: 205 EDEEGYNDGEVDGEEDEEELGEEERGQK 232
           E+ EG  + E    + EE  G+EE+G++
Sbjct: 762 EEVEGEREKEEGERKKEERAGKEEKGEE 789



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 33/80 (41%), Positives = 44/80 (55%), Gaps = 10/80 (12%)

Query: 149  KEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGE-EEDVSGGDEEDE 207
            +E    ++E  VEG + E EGE EE          +EEGEE E+EGE EE+    +EE+E
Sbjct: 1014 EEEEEGEVEGEVEGEEGEGEGEEEE---------GEEEGEEREKEGEGEENRRNREEEEE 1064

Query: 208  EGYNDGEVDGEEDEEELGEE 227
            E     E   EE+E + GEE
Sbjct: 1065 EEGKYQETGEEENERQDGEE 1084



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 5/78 (6%)

Query: 157  EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD 216
            E   E  + EEEGE E E +E+     + EGEEEEE   E +V G + E E    +GE +
Sbjct: 987  EGEGEEEEGEEEGEEEGEGEEEG----EGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEE 1042

Query: 217  GEEDEEELGEEERGQKRK 234
            GEE E+E GE E  ++ +
Sbjct: 1043 GEEREKE-GEGEENRRNR 1059



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 36/94 (38%), Positives = 48/94 (51%), Gaps = 20/94 (21%)

Query: 158 DHVEGLDDEEEGEH--------EEEYDEDAQVVEDEE------GEEEEEEGE------EE 197
           + VEG  ++EEGE         EE+ +E+    E EE      GEE+EE GE      EE
Sbjct: 762 EEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEE 821

Query: 198 DVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQ 231
                +EE+EEG  + E    E+EE  GEEE G+
Sbjct: 822 GKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE 855



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 33/78 (42%), Positives = 45/78 (57%), Gaps = 7/78 (8%)

Query: 157  EDHVEGLDDEE-EGEHEEEYDEDAQVVEDE---EGEEE--EEEGEEEDVSGGDEEDEEGY 210
            E+  EG ++ E EGE EEE + + +V  +E   EGEEE  EEEGEE +  G  EE+    
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRN- 1058

Query: 211  NDGEVDGEEDEEELGEEE 228
             + E + E   +E GEEE
Sbjct: 1059 REEEEEEEGKYQETGEEE 1076



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 21/99 (21%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEE-----GEEEE----------------EEGE 195
           E+  +G  D+  GE E   + + ++ E EE     GEE+E                EEG 
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG 731

Query: 196 EEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234
           EE+   G+EE+ +   + E +GE  EE  GEE  G++ K
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 28/90 (31%), Positives = 50/90 (55%), Gaps = 2/90 (2%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGE-EEEEEGEEEDVSGGDEE 205
           + KE      ++  + +++  E EH E  +E+    E+EE E E +EEGE E+V G  E+
Sbjct: 711 EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770

Query: 206 DEEGYNDGEVDGEEDE-EELGEEERGQKRK 234
           +E      E  G+E++ EE G++  G++ +
Sbjct: 771 EEGERKKEERAGKEEKGEEEGDQGEGEEEE 800



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 29/88 (32%), Positives = 45/88 (51%), Gaps = 7/88 (7%)

Query: 149 KEAPYSDIEDHVEGLDDE--EEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED 206
           K     + ED  EG  D   EEG    E+ +D    E E+GE+++  GE E    G++E 
Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDE---EREKGEKDKGRGEMERPGEGEKEL 696

Query: 207 EEGYNDGEVDGEEDEEELGEEERGQKRK 234
            E     + DGEE E++  E E+G +++
Sbjct: 697 AEKEEWKKRDGEEQEQK--EREQGHQKE 722



 Score = 32.3 bits (72), Expect = 0.36
 Identities = 26/74 (35%), Positives = 35/74 (47%), Gaps = 9/74 (12%)

Query: 166 EEEGEHEEEYDEDAQVVEDEEG---EEEEEEGEEEDVS--GGDEEDEEGYNDGEVDGEED 220
           E   + E E  E+ +  ED +G   EE+E E  EE+V   GG +E  E  +D   D  E 
Sbjct: 577 EAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEV 636

Query: 221 EE----ELGEEERG 230
            E     +GE E G
Sbjct: 637 SEGKAKSVGEAEDG 650


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 60.8 bits (146), Expect = 9e-10
 Identities = 32/62 (51%), Positives = 44/62 (70%), Gaps = 5/62 (8%)

Query: 166 EEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGD----EEDEEGYNDGEVDGEEDE 221
           + EGE EEE +E+ +  E+ EGEEEEEEGEEE+  GG+     E+EE   +G+VD +E+E
Sbjct: 402 KSEGEEEEEEEEEEEE-EEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEE 460

Query: 222 EE 223
           EE
Sbjct: 461 EE 462



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 32/77 (41%), Positives = 46/77 (59%), Gaps = 2/77 (2%)

Query: 152 PYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEE--GEEEDVSGGDEEDEEG 209
           P + I   ++   +EEE E EEE +E+ +  E+EE  EEEEE  GE E++   +E +EEG
Sbjct: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG 452

Query: 210 YNDGEVDGEEDEEELGE 226
             D + + EEDEE   E
Sbjct: 453 DVDSDEEEEEDEESSSE 469



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 27/48 (56%), Positives = 33/48 (68%), Gaps = 3/48 (6%)

Query: 182 VEDEEGEEEEEEGEEEDVSG-GDEEDEEGYNDGEVDGEEDEEELGEEE 228
           ++ E  EEEEEE EEE+  G G+EE+EEG  + E  GE   EELGEEE
Sbjct: 401 LKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGE--GEELGEEE 446



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 53/133 (39%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEE-------------YDEDAQVVEDEEGEEEEE- 192
           + +E    + E+  EG ++EEEGE EEE              +E+  V  DEE EE+EE 
Sbjct: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEES 466

Query: 193 --------------------------------------EGEEEDVSGGDEEDEEGYNDGE 214
                                                 EG E+  S  +EED+E  +D +
Sbjct: 467 SSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDED 526

Query: 215 VDGEEDEEELGEE 227
            D ++DEE+ G+E
Sbjct: 527 EDDDDDEED-GDE 538



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 30/102 (29%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVE--DEEGEEEEEEGEEEDVSGGDEED-------- 206
           E+  EG ++EEEG   EE  E+ +V E  D + +EEEEE EE    G + ED        
Sbjct: 424 EEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEA 483

Query: 207 --------------------EEGYNDGEVDGEEDEEELGEEE 228
                                EG  D + D EE+++E  ++E
Sbjct: 484 GGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDE 525



 Score = 32.0 bits (71), Expect = 0.47
 Identities = 14/38 (36%), Positives = 25/38 (65%), Gaps = 3/38 (7%)

Query: 162 GLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDV 199
           G D + + E E++ +ED    EDE+ +++EE+G+E  V
Sbjct: 507 GEDSDSDSEEEDDEEEDD---EDEDDDDDEEDGDEVPV 541


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 30/82 (36%), Positives = 48/82 (58%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED 206
           D       D  D  E +D++EE E EE  +++ +  +++E +EE +  EEE++   DE+D
Sbjct: 83  DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142

Query: 207 EEGYNDGEVDGEEDEEELGEEE 228
           +E   D E + EE+EEE  EEE
Sbjct: 143 DEDGEDVEDEEEEEEEEEEEEE 164



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 28/86 (32%), Positives = 49/86 (56%), Gaps = 4/86 (4%)

Query: 145 YWDHKEAPYSDIEDHVEGLDDEEEG--EHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGG 202
           Y +  + P  + E+  EG  +EEE   E +E+ DED + VEDEE  EEEEE EEE+    
Sbjct: 110 YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE--EEEEEEEEEEEEEE 167

Query: 203 DEEDEEGYNDGEVDGEEDEEELGEEE 228
           +E+ +   ++  +  + ++++   +E
Sbjct: 168 NEDHQMNCHNTRIMQDTEKDDNNNDE 193



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 5/74 (6%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED 206
           + +E    D +D  +G D E+E E EEE +E     E+EE E E+ +    +     + +
Sbjct: 131 EEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE-----EEEEEENEDHQMNCHNTRIMQDTE 185

Query: 207 EEGYNDGEVDGEED 220
           ++  N+ E D  ++
Sbjct: 186 KDDNNNDEYDNYDE 199


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 11/89 (12%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVED-EEGEEEEEEGEEEDVSGGDEE 205
           DH+       ++     ++EEEG  EE+ +ED +V ED EE EE +E+GEEE+    +EE
Sbjct: 182 DHETGSSGSSDEQGNNTENEEEGV-EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240

Query: 206 DEEGYNDGEVDGEEDEEELGEEERGQKRK 234
           +EE         EE+EEE  ++ER QK +
Sbjct: 241 EEE---------EEEEEEYEQDERDQKEE 260



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 32/76 (42%), Positives = 43/76 (56%), Gaps = 8/76 (10%)

Query: 167 EEGEHEEEYDEDAQV----VEDEEGE--EEEEEGEEEDVSGGDEEDEEGYNDGEVD--GE 218
           +E  + EEY  D +       DE+G   E EEEG EEDV   +E +E+   D EVD  GE
Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230

Query: 219 EDEEELGEEERGQKRK 234
           E+EEE  EEE  ++ +
Sbjct: 231 EEEEEEEEEEEEEEEE 246



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 1/71 (1%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD 216
           ED  E  + EE+ E +EE DED +  E+EE EEEEEE EEE+     +E ++     + D
Sbjct: 207 EDVEEDEEVEEDAEEDEEVDEDGEEEEEEE-EEEEEEEEEEEEEYEQDERDQKEEGNDYD 265

Query: 217 GEEDEEELGEE 227
              +  + G E
Sbjct: 266 TRSEASDSGSE 276



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 25/77 (32%), Positives = 40/77 (51%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED 206
           + +E    D+E+  E  +D EE E  +E  E+ +  E+EE EEEEEE EE +    D+++
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259

Query: 207 EEGYNDGEVDGEEDEEE 223
           E    D   +  +   E
Sbjct: 260 EGNDYDTRSEASDSGSE 276



 Score = 36.2 bits (82), Expect = 0.025
 Identities = 19/77 (24%), Positives = 37/77 (48%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD 216
           ED  E  ++EEE E EEE +E+    ++ + +EE  + +    +     +   + DG V 
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286

Query: 217 GEEDEEELGEEERGQKR 233
                +   E+++ +KR
Sbjct: 287 SGSGTDGSDEKKKERKR 303



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 150 EAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEE--EEGEEEDVSGGDEEDE 207
           ++P  D  + + GL+ +       +  ++ +V  +E G + E    G  ++     E +E
Sbjct: 145 KSPTPDGSERI-GLEVDRRASRSSQSSKE-EVNSEEYGSDHETGSSGSSDEQGNNTENEE 202

Query: 208 EGYNDGEVDGEEDEEELGEEE 228
           EG  +   + EE EE+  E+E
Sbjct: 203 EGVEEDVEEDEEVEEDAEEDE 223


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 11/89 (12%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVED-EEGEEEEEEGEEEDVSGGDEE 205
           DH+       ++     ++EEEG  EE+ +ED +V ED EE EE +E+GEEE+    +EE
Sbjct: 182 DHETGSSGSSDEQGNNTENEEEGV-EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEE 240

Query: 206 DEEGYNDGEVDGEEDEEELGEEERGQKRK 234
           +EE         EE+EEE  ++ER QK +
Sbjct: 241 EEE---------EEEEEEYEQDERDQKEE 260



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 32/76 (42%), Positives = 43/76 (56%), Gaps = 8/76 (10%)

Query: 167 EEGEHEEEYDEDAQV----VEDEEGE--EEEEEGEEEDVSGGDEEDEEGYNDGEVD--GE 218
           +E  + EEY  D +       DE+G   E EEEG EEDV   +E +E+   D EVD  GE
Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230

Query: 219 EDEEELGEEERGQKRK 234
           E+EEE  EEE  ++ +
Sbjct: 231 EEEEEEEEEEEEEEEE 246



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 1/71 (1%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD 216
           ED  E  + EE+ E +EE DED +  E+EE EEEEEE EEE+     +E ++     + D
Sbjct: 207 EDVEEDEEVEEDAEEDEEVDEDGEEEEEEE-EEEEEEEEEEEEEYEQDERDQKEEGNDYD 265

Query: 217 GEEDEEELGEE 227
              +  + G E
Sbjct: 266 TRSEASDSGSE 276



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 25/77 (32%), Positives = 40/77 (51%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED 206
           + +E    D+E+  E  +D EE E  +E  E+ +  E+EE EEEEEE EE +    D+++
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259

Query: 207 EEGYNDGEVDGEEDEEE 223
           E    D   +  +   E
Sbjct: 260 EGNDYDTRSEASDSGSE 276



 Score = 36.2 bits (82), Expect = 0.025
 Identities = 19/77 (24%), Positives = 37/77 (48%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD 216
           ED  E  ++EEE E EEE +E+    ++ + +EE  + +    +     +   + DG V 
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286

Query: 217 GEEDEEELGEEERGQKR 233
                +   E+++ +KR
Sbjct: 287 SGSGTDGSDEKKKERKR 303



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 150 EAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEE--EEGEEEDVSGGDEEDE 207
           ++P  D  + + GL+ +       +  ++ +V  +E G + E    G  ++     E +E
Sbjct: 145 KSPTPDGSERI-GLEVDRRASRSSQSSKE-EVNSEEYGSDHETGSSGSSDEQGNNTENEE 202

Query: 208 EGYNDGEVDGEEDEEELGEEE 228
           EG  +   + EE EE+  E+E
Sbjct: 203 EGVEEDVEEDEEVEEDAEEDE 223


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 32/72 (44%), Positives = 47/72 (65%), Gaps = 2/72 (2%)

Query: 159 HVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEE--EDVSGGDEEDEEGYNDGEVD 216
           ++   D+EEE E EEE +E+ +  E+E+ EEEEE+ EE  E+    +EE EE + + E +
Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941

Query: 217 GEEDEEELGEEE 228
            EE+EEE  EEE
Sbjct: 942 LEEEEEEEDEEE 953



 Score = 58.2 bits (139), Expect = 6e-09
 Identities = 33/69 (47%), Positives = 44/69 (63%), Gaps = 5/69 (7%)

Query: 165 DEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEE-----GYNDGEVDGEE 219
           DEEE E EEE +E+ +  E+EE  EEEEE EEE     +EE+EE        +GE++ EE
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 220 DEEELGEEE 228
           +EE+  EEE
Sbjct: 947 EEEDEEEEE 955



 Score = 54.7 bits (130), Expect = 7e-08
 Identities = 32/72 (44%), Positives = 44/72 (61%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD 216
           E+  E  ++EEE E EEE D + +  ++EE  EEEEE EEE     +EE+ E   + E +
Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE 949

Query: 217 GEEDEEELGEEE 228
            EE+EEEL E E
Sbjct: 950 DEEEEEELEEVE 961



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 32/76 (42%), Positives = 44/76 (57%), Gaps = 8/76 (10%)

Query: 156 IEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEV 215
           +E+ +  ++     E EEE        E+EE EEEEEE EEE+    +EEDEE Y + E 
Sbjct: 874 LEEDLTVININSSDEEEEE--------EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE 925

Query: 216 DGEEDEEELGEEERGQ 231
           + EE+ EE  EEE G+
Sbjct: 926 EEEEEFEEEFEEEEGE 941



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 30/77 (38%), Positives = 42/77 (54%), Gaps = 2/77 (2%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEE--GEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDE 204
           + +E    + ED  E  +DEEE   E EEE +E  +  E+EEGE EEEE EE++    + 
Sbjct: 898 EEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957

Query: 205 EDEEGYNDGEVDGEEDE 221
           E+ E    G   GE +E
Sbjct: 958 EEVEDLEFGTAGGEVEE 974



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 9/65 (13%)

Query: 145 YWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDE 204
           Y++ +E    + E+  E    EEEGE EEE +E     EDEE EEE EE E+ +      
Sbjct: 920 YFEEEEEEEEEFEEEFE----EEEGELEEEEEE-----EDEEEEEELEEVEDLEFGTAGG 970

Query: 205 EDEEG 209
           E EEG
Sbjct: 971 EVEEG 975


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 31/74 (41%), Positives = 43/74 (58%)

Query: 158 DHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDG 217
           D  E +  +EE E  E      +V E+ E EEEEEE EEED    +EE+EEG ++G    
Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGD 563

Query: 218 EEDEEELGEEERGQ 231
           EEDE+   E++ G+
Sbjct: 564 EEDEKVSDEKDSGK 577



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 20/97 (20%)

Query: 148 HKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED- 206
           H E   +  E+  E  ++EE+ E EEE        E+EEGE E  EG+EED    DE+D 
Sbjct: 524 HIEVKENPEEEEEEEEEEEEDEESEEE--------EEEEGESEGSEGDEEDEKVSDEKDS 575

Query: 207 ---------EEGYNDGEVDGEEDEEELGEEERGQKRK 234
                    +E  +D E D ++D  +  EE    K K
Sbjct: 576 GKTLDKKPSKEMSSDSEYDSDDDRTK--EERAYDKAK 610



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 165 DEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGE--EDEE 222
           +EEE   +   D+   +  DEE E+ E      +V    EE+EE   + E D E  E+EE
Sbjct: 493 EEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEE 552

Query: 223 ELGEEE 228
           E GE E
Sbjct: 553 EEGESE 558



 Score = 30.8 bits (68), Expect = 1.0
 Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 17/87 (19%)

Query: 164 DDEEEGEHEEEYDEDAQVVEDEEGEEEEEEG----------------EEEDVSGGDEEDE 207
           +D+ EG+ +++ D+  +  E EE E+E+++G                +EE+     EE+E
Sbjct: 306 EDDNEGDKKKK-DKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEE 364

Query: 208 EGYNDGEVDGEEDEEELGEEERGQKRK 234
                 E++ +  EEE  E+E+ +++K
Sbjct: 365 RIKRLEELEAKRKEEERLEQEKRERKK 391


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 30/70 (42%), Positives = 42/70 (60%)

Query: 164 DDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEE 223
           +DEEE E EEE +ED +  E+EE EEEEEE EEE+    +EE+EE     +V  +ED   
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319

Query: 224 LGEEERGQKR 233
              ++  + R
Sbjct: 320 TSAQKAPELR 329



 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 29/57 (50%), Positives = 37/57 (64%)

Query: 156 IEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYND 212
           I  H E  ++EEE E EEE DE+ +  E+EE EEEEEE EEE+    +EE+EE   D
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310



 Score = 52.8 bits (125), Expect = 3e-07
 Identities = 30/61 (49%), Positives = 38/61 (62%), Gaps = 9/61 (14%)

Query: 163 LDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEE 222
           L  EEE E EEE +E+ +  E+EE EEEEEE EEE+    +EE+EE         EE+EE
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE---------EEEEE 305

Query: 223 E 223
           E
Sbjct: 306 E 306



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 27/66 (40%), Positives = 39/66 (59%)

Query: 167 EEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGE 226
           E+   EE   +   +  +EE EEEEEE EEE+    +EE+EE   + E + EE+EEE  E
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300

Query: 227 EERGQK 232
           EE  ++
Sbjct: 301 EEEEEE 306



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 28/68 (41%), Positives = 40/68 (58%)

Query: 161 EGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEED 220
           + L+D    E  ++    +   EDEE EEEEEE EE++    +EE+EE   + E + EE+
Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297

Query: 221 EEELGEEE 228
           EEE  EEE
Sbjct: 298 EEEEEEEE 305



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 25/50 (50%), Positives = 33/50 (66%)

Query: 148 HKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEE 197
           H+E    + E+  E  +DEEE E EEE +E+ +  E+EE EEEEEE EEE
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 34/75 (45%), Positives = 45/75 (60%), Gaps = 10/75 (13%)

Query: 156 IEDHVEGLDDEEEG--EHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDG 213
           +ED       +++G   HEEE DE     E+EE EEEEEE EEE+    +EE+EE   + 
Sbjct: 240 LEDAASEESSKQKGILSHEEE-DE-----EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEE 293

Query: 214 EVDGEEDEEELGEEE 228
           E + EE+EEE  EEE
Sbjct: 294 EEEEEEEEEE--EEE 306



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 168 EGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEE 227
           E    EE  +   ++  EE E+EEEE EEE+    +EE+EE   + E + EE+EEE  EE
Sbjct: 241 EDAASEESSKQKGILSHEE-EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299

Query: 228 ERGQKRK 234
           E  ++ +
Sbjct: 300 EEEEEEE 306



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 22/53 (41%), Positives = 31/53 (58%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDV 199
           +  E    + E+  E  ++EEE E EEE +E+ +  E+EE EEEEEE    DV
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 23/73 (31%), Positives = 37/73 (50%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED 206
           + +E    + E+  +  ++EEE E EEE +E+ +  E+EE EEEEEE   + +   D   
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319

Query: 207 EEGYNDGEVDGEE 219
                  E+ G E
Sbjct: 320 TSAQKAPELRGPE 332



 Score = 34.3 bits (77), Expect = 0.095
 Identities = 21/71 (29%), Positives = 36/71 (50%)

Query: 164 DDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEE 223
           D EE  E   E  +D      E+   EE   ++  +S  +E++EE   + E + +E+EEE
Sbjct: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279

Query: 224 LGEEERGQKRK 234
             EEE  ++ +
Sbjct: 280 EEEEEEEEEEE 290



 Score = 31.2 bits (69), Expect = 0.80
 Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 11/82 (13%)

Query: 163 LDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEE----------EDVSGGDEEDEEGYND 212
           L +  EG   EE  E    ++ E+ EE  E   E          ED +  +   ++G   
Sbjct: 198 LQEAAEGAASEE-GEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILS 256

Query: 213 GEVDGEEDEEELGEEERGQKRK 234
            E + EE+EEE  EEE  ++ +
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEE 278


>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
          Length = 543

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 12/111 (10%)

Query: 135 LLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEE-------EGEHEEEYDEDAQVVEDEEG 187
           L+      S Y  H +    ++E+ +E    EE       EGE EEE ++D +  E+EE 
Sbjct: 433 LMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEE-EKDKEEAEEEEA 491

Query: 188 EEEEEEGEEEDVSGGDEED----EEGYNDGEVDGEEDEEELGEEERGQKRK 234
            EEEE  +EE     +EE+    EEG    E + EE + E   EE+  K+K
Sbjct: 492 AEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQAAKKK 542



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 5/77 (6%)

Query: 149 KEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEE-----EEEGEEEDVSGGD 203
           K+ P S+ E   E  D EE  E E   +E+A   E EE +EE      EEGEE   +  +
Sbjct: 467 KDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEE 526

Query: 204 EEDEEGYNDGEVDGEED 220
           E+  EG  + +   ++D
Sbjct: 527 EKKVEGAGEEQAAKKKD 543


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/70 (48%), Positives = 41/70 (58%), Gaps = 14/70 (20%)

Query: 164 DDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEE 223
           D+EEE + EE           EE EEEEEEGEEE   GG EE EEG   GE +  E+EEE
Sbjct: 221 DEEEEEKEEE-----------EEKEEEEEEGEEE---GGGEEGEEGGGGGEGEETEEEEE 266

Query: 224 LGEEERGQKR 233
             EEE  +++
Sbjct: 267 EEEEEEEEEQ 276



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 29/71 (40%), Positives = 43/71 (60%), Gaps = 3/71 (4%)

Query: 163 LDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEE 222
           ++DEEE E EEE +++    E+EEGEEE    E E+  GG E +E    + E + EE+EE
Sbjct: 219 VEDEEEEEKEEEEEKEE---EEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEE 275

Query: 223 ELGEEERGQKR 233
           ++   +  QKR
Sbjct: 276 QIKAFQEKQKR 286



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 23/45 (51%), Positives = 28/45 (62%), Gaps = 3/45 (6%)

Query: 157 EDHVEGLDDEEEGEHE---EEYDEDAQVVEDEEGEEEEEEGEEED 198
           E+  E  ++EEEGE E   EE +E     E EE EEEEEE EEE+
Sbjct: 228 EEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEE 272



 Score = 35.8 bits (81), Expect = 0.033
 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 10/52 (19%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEG----------EEEEEEGEEED 198
           E+  E  ++EE+ E EEE +E+    E EEG          EEEEEE EEE+
Sbjct: 222 EEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEE 273



 Score = 32.7 bits (73), Expect = 0.28
 Identities = 23/52 (44%), Positives = 28/52 (53%), Gaps = 18/52 (34%)

Query: 181 VVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQK 232
           VVEDEE EE+EEE E+E      EE+EEG            EE G  E G++
Sbjct: 218 VVEDEEEEEKEEEEEKE------EEEEEG------------EEEGGGEEGEE 251


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 31/90 (34%), Positives = 55/90 (61%), Gaps = 7/90 (7%)

Query: 150 EAPYSD---IEDHVEGLDD--EEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDE 204
           EAP S+   +E   E ++D  E+ GE +E    + +  E+++ E+EE++ EE+  +G ++
Sbjct: 89  EAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148

Query: 205 EDEEGYNDGEVD--GEEDEEELGEEERGQK 232
           +DE+G  DG+ D  G E  E+  E+E G+K
Sbjct: 149 KDEKGEEDGKEDKNGNEKGEDAKEKEDGKK 178



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 27/91 (29%), Positives = 55/91 (60%), Gaps = 4/91 (4%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEE---EEEEGEEEDVSGGD 203
           + KEA  +++++  E   ++EE ++EE+  E  +  +DE+GEE   E++ G E+     +
Sbjct: 114 EKKEAVAAEVKNEEEDQKEDEEDQNEEK-GEAGKEDKDEKGEEDGKEDKNGNEKGEDAKE 172

Query: 204 EEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234
           +ED +   DG+ +GE+ +E+  +E+  + RK
Sbjct: 173 KEDGKKGEDGKGNGEDGKEKGEDEKEEEDRK 203



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 26/76 (34%), Positives = 46/76 (60%), Gaps = 5/76 (6%)

Query: 162 GLDDEEEGEHEEEYDEDAQV---VEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGE 218
           G D +E+GE E+E ++  +     E+E+G+E+ ++ E +DV    +EDE+   DG+ D  
Sbjct: 186 GEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVK--VKEDEKEREDGKEDEG 243

Query: 219 EDEEELGEEERGQKRK 234
            +EEE G+E+   K +
Sbjct: 244 GNEEEAGKEKEDLKEE 259



 Score = 41.6 bits (96), Expect = 6e-04
 Identities = 25/76 (32%), Positives = 45/76 (59%), Gaps = 2/76 (2%)

Query: 161 EGLDDEEEGEHEEEYDEDAQVVED-EEGEEEEEEGEEEDVSGGDEEDEEGYND-GEVDGE 218
           +G +D +E ++  E  EDA+  ED ++GE+ +  GE+    G DE++EE   + G+    
Sbjct: 152 KGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKEN 211

Query: 219 EDEEELGEEERGQKRK 234
           ED +E G+++ G+  K
Sbjct: 212 EDGKEKGDKKEGKDVK 227



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 25/84 (29%), Positives = 48/84 (57%), Gaps = 4/84 (4%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEE--EEEGEEEDVSGGDE 204
           + +E    +  D  E  D +E+G+ +E   +D +V EDE+  E+  E+EG  E+ +G ++
Sbjct: 196 EKEEEDRKETGDGKENEDGKEKGDKKE--GKDVKVKEDEKEREDGKEDEGGNEEEAGKEK 253

Query: 205 EDEEGYNDGEVDGEEDEEELGEEE 228
           ED +   +G+ + E  E++  +EE
Sbjct: 254 EDLKEEEEGKEEDEIKEDDGKKEE 277



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 17/90 (18%)

Query: 157 EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEG------EEEEEEGEEED--VSGGDEEDEE 208
           ED  E  +  E+GE  +E  ED +  ED +G      E+ E+E EEED   +G  +E+E+
Sbjct: 155 EDGKEDKNGNEKGEDAKE-KEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENED 213

Query: 209 GYNDGE--------VDGEEDEEELGEEERG 230
           G   G+        V  +E E E G+E+ G
Sbjct: 214 GKEKGDKKEGKDVKVKEDEKEREDGKEDEG 243



 Score = 31.6 bits (70), Expect = 0.61
 Identities = 19/76 (25%), Positives = 38/76 (50%), Gaps = 5/76 (6%)

Query: 164 DDEEEGEHEEEYDE-----DAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGE 218
           + ++E   EE+Y+E     +A++ E    E+E  E +EE++    E+  E       + +
Sbjct: 65  ETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVK 124

Query: 219 EDEEELGEEERGQKRK 234
            +EE+  E+E  Q  +
Sbjct: 125 NEEEDQKEDEEDQNEE 140


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 30/71 (42%), Positives = 45/71 (63%), Gaps = 7/71 (9%)

Query: 157  EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVD 216
            ED +  LD E+E EH +E D      EDE+  ++EEE EEE     DEED++  ++GE +
Sbjct: 2401 EDSMNILDPEDEEEHTQEEDSSGSN-EDEDDSQDEEEEEEE-----DEEDDQEDDEGE-E 2453

Query: 217  GEEDEEELGEE 227
            G+ED+++ G E
Sbjct: 2454 GDEDDDDDGSE 2464



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 24/67 (35%), Positives = 41/67 (61%), Gaps = 10/67 (14%)

Query: 150  EAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEG 209
            E  ++  ED     +DE++ + EEE +E     EDEE ++E++EGEE     GDE+D++ 
Sbjct: 2412 EEEHTQEEDSSGSNEDEDDSQDEEEEEE-----EDEEDDQEDDEGEE-----GDEDDDDD 2461

Query: 210  YNDGEVD 216
             ++ E+D
Sbjct: 2462 GSEMELD 2468



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 24/56 (42%), Positives = 35/56 (62%), Gaps = 3/56 (5%)

Query: 177  EDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQK 232
            ED+  + D E  +EEE  +EED S G  EDE+   D E + EEDEE+  E++ G++
Sbjct: 2401 EDSMNILDPE--DEEEHTQEED-SSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEE 2453



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 18/56 (32%), Positives = 33/56 (58%)

Query: 157  EDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYND 212
            E+   G +++E+   +EE +E+    +D+E +E EE  E++D  G + E +E Y D
Sbjct: 2418 EEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPD 2473



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 12/46 (26%), Positives = 27/46 (58%)

Query: 155  DIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVS 200
            D +D  E  +++EE + E++  E+    +D++G E E + +  D++
Sbjct: 2430 DSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMN 2475


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 28/69 (40%), Positives = 45/69 (65%), Gaps = 1/69 (1%)

Query: 161  EGLDDEEEGEHEEEYD-EDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEE 219
            E L  EEE E EEE + E+ +V E+EE  +EEEEGEE+ V   +EE ++   + + +  +
Sbjct: 2241 ESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQ 2300

Query: 220  DEEELGEEE 228
            ++EE+ EE+
Sbjct: 2301 EKEEVFEEK 2309



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 33/91 (36%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 147  DHKEAPYSDIEDHVEG---LDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGD 203
            D  +  +S   D VE      +E E   +E   +++   E+EE  EEEEE EEE+V   +
Sbjct: 2207 DKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEE 2266

Query: 204  EEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234
            EE +E     E +GEE + E  EEE+ +K+K
Sbjct: 2267 EERKE-----EEEGEEKQVEKEEEEKKKKKK 2292



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 1/83 (1%)

Query: 147  DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEE-EEGEEEDVSGGDEE 205
            D  E   S   +  E  ++EEE E EE  +E+ +  E+EEGEE++ E+ EEE      E+
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294

Query: 206  DEEGYNDGEVDGEEDEEELGEEE 228
             +E   + E   EE EE + EEE
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEE 2317



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 8/123 (6%)

Query: 120  EVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDA 179
            EV +   + E +  LL +L   +S   + +E    + E   E + +EEE   EEE  E+ 
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK 2278

Query: 180  QVV-EDEEGEEEEEEGEEEDVSGGDE---EDEEGYNDGEV----DGEEDEEELGEEERGQ 231
            QV  E+EE +++++E ++E+V   +E   E EE  ++ E     D EE+EE    EE   
Sbjct: 2279 QVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVD 2338

Query: 232  KRK 234
            + K
Sbjct: 2339 REK 2341



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 6/95 (6%)

Query: 146  WDHKEAPYS--DIEDHVEGLDDEEEGEHEEE---YDEDAQVVEDEEGEEEEEEGEEEDVS 200
            W  KE      ++E  +E L  +EE  ++EE    +E  ++ E+EE    + E   E+ +
Sbjct: 1709 WQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEET 1768

Query: 201  GGDEEDEEGYNDGEVDGEEDEEELGEEER-GQKRK 234
               +E+E    + E   +  E+   EEER G+KR+
Sbjct: 1769 KLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKRE 1803



 Score = 27.7 bits (60), Expect = 8.9
 Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 13/74 (17%)

Query: 161  EGLDDEEEGEHEEE---YDEDAQVVED--EEGEEEEEEGEEEDVSGGDEEDEEGYNDGEV 215
            E L  EEE   E++   ++E  QV E+      +E++  +EE+V+  +E   EG      
Sbjct: 1501 EKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREG------ 1554

Query: 216  DGEEDEEELGEEER 229
              EE E+++ EE+R
Sbjct: 1555 --EEKEQQVTEEQR 1566


>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
          Length = 1812

 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 148 HKEAPYSDIEDHVEGLDDE----EEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGD 203
           H+E  +  I      +  E    +EGE EEE  E+ +  ED+   EEEE+ +E+D    D
Sbjct: 213 HREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVD 272

Query: 204 EEDEEGYNDGEVDGEEDEEELGEE 227
              EE   D E +GEEDEE  G++
Sbjct: 273 SIPEEEEEDEEEEGEEDEEGEGDD 296



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 32/84 (38%), Positives = 48/84 (57%), Gaps = 8/84 (9%)

Query: 149 KEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEE 208
           +E  YSD     EG + EEE + E E DED   VE+EE E+E++    + +   +EEDEE
Sbjct: 230 QEGQYSD-----EG-EVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEE 283

Query: 209 --GYNDGEVDGEEDEEELGEEERG 230
             G  D E +G++  E++  +E G
Sbjct: 284 EEGEEDEEGEGDDGYEQISSDEDG 307



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 4/84 (4%)

Query: 149 KEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEE 208
           ++AP+   ED+ E +  +     +E    D   VE+E+ EE EE  +E+DV   +EEDE+
Sbjct: 209 EDAPHR--EDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEE--DEDDVDVEEEEDED 264

Query: 209 GYNDGEVDGEEDEEELGEEERGQK 232
             +   VD   +EEE  EEE G++
Sbjct: 265 EDDRRTVDSIPEEEEEDEEEEGEE 288



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 15/70 (21%)

Query: 147 DHKEAPYSDIEDH--VEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDE 204
           D +E    D +D   V+ + +EEE + EEE              EE+EEGE +D      
Sbjct: 256 DVEEEEDEDEDDRRTVDSIPEEEEEDEEEE-------------GEEDEEGEGDDGYEQIS 302

Query: 205 EDEEGYNDGE 214
            DE+G  D E
Sbjct: 303 SDEDGIADLE 312


>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
          Length = 1147

 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query: 148 HKEAPYSDIEDHVEGLDDE----EEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGD 203
           H+E  +  I      +  E    +EGE EEE  E+ +  ED+   EEEE+ +E+D    D
Sbjct: 213 HREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVD 272

Query: 204 EEDEEGYNDGEVDGEEDEEELGEE 227
              EE   D E +GEEDEE  G++
Sbjct: 273 SIPEEEEEDEEEEGEEDEEGEGDD 296



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 32/84 (38%), Positives = 48/84 (57%), Gaps = 8/84 (9%)

Query: 149 KEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEE 208
           +E  YSD     EG + EEE + E E DED   VE+EE E+E++    + +   +EEDEE
Sbjct: 230 QEGQYSD-----EG-EVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEE 283

Query: 209 --GYNDGEVDGEEDEEELGEEERG 230
             G  D E +G++  E++  +E G
Sbjct: 284 EEGEEDEEGEGDDGYEQISSDEDG 307



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 4/84 (4%)

Query: 149 KEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEE 208
           ++AP+   ED+ E +  +     +E    D   VE+E+ EE EE  +E+DV   +EEDE+
Sbjct: 209 EDAPHR--EDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEE--DEDDVDVEEEEDED 264

Query: 209 GYNDGEVDGEEDEEELGEEERGQK 232
             +   VD   +EEE  EEE G++
Sbjct: 265 EDDRRTVDSIPEEEEEDEEEEGEE 288



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 15/70 (21%)

Query: 147 DHKEAPYSDIEDH--VEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDE 204
           D +E    D +D   V+ + +EEE + EEE              EE+EEGE +D      
Sbjct: 256 DVEEEEDEDEDDRRTVDSIPEEEEEDEEEE-------------GEEDEEGEGDDGYEQIS 302

Query: 205 EDEEGYNDGE 214
            DE+G  D E
Sbjct: 303 SDEDGIADLE 312


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 57/184 (30%), Positives = 83/184 (45%), Gaps = 26/184 (14%)

Query: 25  DNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDLPKLKLRKLELRVSGGLEVLAEKCP 84
           DN+ + +G + A+ +  + L  +  IN G   +     + +      + GGL       P
Sbjct: 245 DNTFTEKGAV-AMAETLKTLRQVEVINFGDCLVRSKGAVAIADA---IRGGL-------P 293

Query: 85  NLTHLYLSGNKIKD---LSTIEPLKQLENLKSLDLFNCEVTNLNDYGENVFKLLLQLTYL 141
            L  L LS  +IK    L+  E +     L+ LDL      N N  GE   + L ++  L
Sbjct: 294 KLKELNLSFCEIKRDAALAVAEAMADKAELEKLDL------NGNTLGEEGCEQLQEV--L 345

Query: 142 DSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSG 201
           +        A  SD ED     ++EEEGE EEE  E+ +  ++EE EEEEEE EEE    
Sbjct: 346 EGFNMAKVLASLSDDEDE----EEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQR 401

Query: 202 GDEE 205
           G  E
Sbjct: 402 GQGE 405



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 25/53 (47%), Positives = 36/53 (67%), Gaps = 3/53 (5%)

Query: 182 VEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234
           + D+E EEEEEEGEEE+    +EE+E+   + E + EE+EEE   ++RGQ  K
Sbjct: 357 LSDDEDEEEEEEGEEEEEEAEEEEEED---EEEEEEEEEEEEEEPQQRGQGEK 406


>gi|66472382 nischarin [Homo sapiens]
          Length = 1504

 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 28/70 (40%), Positives = 41/70 (58%), Gaps = 4/70 (5%)

Query: 160 VEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEE 219
           +E  +  EEG+ E+  +ED    E+EE EE+  E    ++   D E+EEG   GE + EE
Sbjct: 622 IEAANQREEGQGEQGEEED----EEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEE 677

Query: 220 DEEELGEEER 229
           +E+E  EEER
Sbjct: 678 EEDEEAEEER 687



 Score = 28.1 bits (61), Expect = 6.8
 Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 47  LSKINGGLTSISDLPKLKLRKLELRVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLK 106
           LS + G  T + ++  L L    L    GL     K  +L +L L  N+I+ +  +  + 
Sbjct: 344 LSSLEGLHTKLGNIKTLNLAGNLLESLSGLH----KLYSLVNLDLRDNRIEQMEEVRSIG 399

Query: 107 QLENLKSLDLFNCEVTNLNDYGENV 131
            L  L+ + L N  ++ + DY   V
Sbjct: 400 SLPCLEHVSLLNNPLSIIPDYRTKV 424


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 32/102 (31%), Positives = 56/102 (54%), Gaps = 18/102 (17%)

Query: 151 APYSDIEDHVEGLDDEEEGEHEEEYDED-------------AQVVEDE-----EGEEEEE 192
           AP S+ ED  +  DDE++ + EE+  E+             A+VV  +     E E+EEE
Sbjct: 181 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240

Query: 193 EGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234
           + E+ED    ++++++   D E + EE+EEE  +E  G+++K
Sbjct: 241 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKK 282



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 24/75 (32%), Positives = 35/75 (46%)

Query: 158 DHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDG 217
           D  E  D EE+ E +E+ DED   +E    +        ED    D+ED+E  +D E D 
Sbjct: 146 DEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDD 205

Query: 218 EEDEEELGEEERGQK 232
            E+E       +G+K
Sbjct: 206 SEEEAMETTPAKGKK 220



 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 1/68 (1%)

Query: 161 EGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEED 220
           E  D+EE+ + EE+ ++D    EDE+  E             ++ED+E   D E D ++D
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDE-DDDDD 201

Query: 221 EEELGEEE 228
           EE+  EEE
Sbjct: 202 EEDDSEEE 209



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 20/69 (28%), Positives = 36/69 (52%)

Query: 164 DDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEE 223
           D +EE + + E DE+    EDE+ +E E    +   +    EDE+  +D + + ++D+EE
Sbjct: 144 DSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEE 203

Query: 224 LGEEERGQK 232
              EE   +
Sbjct: 204 DDSEEEAME 212



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 50/125 (40%)

Query: 154 SDIEDHVEGLDDEEEGEHEEE-------------------YDEDAQVVEDEEGEEEEE-- 192
           SD E+  +  +DEE+ E E+E                    DED +  ED+E ++++E  
Sbjct: 145 SDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEED 204

Query: 193 -----------------------------EGEEEDVSGGDEEDEEGYNDGEVDGEEDEEE 223
                                        E E+E+    DE+D++  +D + D E+DEEE
Sbjct: 205 DSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEE 264

Query: 224 LGEEE 228
             EEE
Sbjct: 265 EEEEE 269



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 14/55 (25%), Positives = 32/55 (58%)

Query: 155 DIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEG 209
           D +D  +  DD++E + EEE +E+ + V++  G+ ++E  +++      ++  EG
Sbjct: 246 DDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEG 300



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 7/40 (17%)

Query: 185 EEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEEL 224
           +  ++E+ + EE+D S  DEED+E       D +EDE+E+
Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDE-------DEDEDEDEI 170


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 5/67 (7%)

Query: 162 GLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDE 221
           G   EEE E EEE +E+    E+ E EEEEEE EEE+     EE  E     +   E  E
Sbjct: 275 GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE-----QSAEEVSE 329

Query: 222 EELGEEE 228
           EE+ E+E
Sbjct: 330 EEMSEDE 336



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 29/63 (46%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 165 DEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYND-GEVDGEEDEEE 223
           +EEE E EEE +E +   E EE EEEEEE EEE  S  +E  E+   +  E +  EDEE 
Sbjct: 279 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 338

Query: 224 LGE 226
             E
Sbjct: 339 ENE 341



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 7/84 (8%)

Query: 154 SDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEG------EEEDVSGGDEEDE 207
           SD++D  +        E            E+EE EEEEEEG      EEE+    +EE+E
Sbjct: 252 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 311

Query: 208 EGYNDGEVDGEEDEEELGEEERGQ 231
            G N  E   E+  EE+ EEE  +
Sbjct: 312 TGSNSEEA-SEQSAEEVSEEEMSE 334



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 4/89 (4%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED 206
           + +E    + E+     + EEE E EEE +E+     +E  E+  EE  EE++S  +E +
Sbjct: 280 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 339

Query: 207 EEGY----NDGEVDGEEDEEELGEEERGQ 231
            E +     +   D +  E E  EEE G+
Sbjct: 340 NENHLLVVPESRFDRDSGESEEAEEEVGE 368



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 8/73 (10%)

Query: 158 DHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDG 217
           D +  L D  + E +    E +   E   G EEEEE EE       EE+EEG    E + 
Sbjct: 249 DLLSDLQDISDSERKTSSAESSSA-ESGSGSEEEEEEEE-------EEEEEGSTSEESEE 300

Query: 218 EEDEEELGEEERG 230
           EE+EEE  EEE G
Sbjct: 301 EEEEEEEEEEETG 313


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 5/67 (7%)

Query: 162 GLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDE 221
           G   EEE E EEE +E+    E+ E EEEEEE EEE+     EE  E     +   E  E
Sbjct: 285 GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE-----QSAEEVSE 339

Query: 222 EELGEEE 228
           EE+ E+E
Sbjct: 340 EEMSEDE 346



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 29/63 (46%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 165 DEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYND-GEVDGEEDEEE 223
           +EEE E EEE +E +   E EE EEEEEE EEE  S  +E  E+   +  E +  EDEE 
Sbjct: 289 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 348

Query: 224 LGE 226
             E
Sbjct: 349 ENE 351



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 7/84 (8%)

Query: 154 SDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEG------EEEDVSGGDEEDE 207
           SD++D  +        E            E+EE EEEEEEG      EEE+    +EE+E
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321

Query: 208 EGYNDGEVDGEEDEEELGEEERGQ 231
            G N  E   E+  EE+ EEE  +
Sbjct: 322 TGSNSEEA-SEQSAEEVSEEEMSE 344



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 4/89 (4%)

Query: 147 DHKEAPYSDIEDHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEED 206
           + +E    + E+     + EEE E EEE +E+     +E  E+  EE  EE++S  +E +
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349

Query: 207 EEGY----NDGEVDGEEDEEELGEEERGQ 231
            E +     +   D +  E E  EEE G+
Sbjct: 350 NENHLLVVPESRFDRDSGESEEAEEEVGE 378



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 8/73 (10%)

Query: 158 DHVEGLDDEEEGEHEEEYDEDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDG 217
           D +  L D  + E +    E +   E   G EEEEE EE       EE+EEG    E + 
Sbjct: 259 DLLSDLQDISDSERKTSSAESSSA-ESGSGSEEEEEEEE-------EEEEEGSTSEESEE 310

Query: 218 EEDEEELGEEERG 230
           EE+EEE  EEE G
Sbjct: 311 EEEEEEEEEEETG 323


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.132    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,931,333
Number of Sequences: 37866
Number of extensions: 577804
Number of successful extensions: 29466
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 861
Number of HSP's successfully gapped in prelim test: 437
Number of HSP's that attempted gapping in prelim test: 4967
Number of HSP's gapped (non-prelim): 10603
length of query: 234
length of database: 18,247,518
effective HSP length: 99
effective length of query: 135
effective length of database: 14,498,784
effective search space: 1957335840
effective search space used: 1957335840
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.