Guide to the Human Genome
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Name: PGLS Sequence: fasta or formatted (258aa) NCBI GI: 6912586
Description:

6-phosphogluconolactonase

Referenced in:

Pentose Phosphate Pathway

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            14.0         36           3
 C cysteine            1.9          5           2
 D aspartate           3.9         10           1
 E glutamate           6.6         17           2
 F phenylalanine       3.9         10           1
 G glycine             6.2         16           2
 H histidine           2.3          6           1
 I isoleucine          3.9         10           1
 K lysine              3.1          8           2
 L leucine            14.3         37           2
 M methionine          0.8          2           1
 N asparagine          1.2          3           1
 P proline             9.3         24           3
 Q glutamine           3.9         10           1
 R arginine            5.4         14           1
 S serine              6.2         16           3
 T threonine           4.7         12           1
 V valine              6.6         17           1
 W tryptophan          0.8          2           1
 Y tyrosine            1.2          3           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   6-phosphogluconolactonase 
H6PD                  0.152   hexose-6-phosphate dehydrogenase precursor 
GNPDA1                0.031   glucosamine-6-phosphate deaminase 1 
GNPDA2                0.029   glucosamine-6-phosphate deaminase 2 
SMTN                  0.012   smoothelin isoform a 
LOC100129697          0.010   PREDICTED: hypothetical protein 
LOC100129697          0.010   PREDICTED: hypothetical protein 
KCNH4                 0.010   potassium voltage-gated channel, subfamily H, member ...
LOC100131381          0.010   PREDICTED: hypothetical protein 
GRIN3B                0.008   glutamate receptor, ionotropic, N-methyl-D-aspartate...
EFTUD2                0.008   elongation factor Tu GTP binding domain containing ...
EFTUD2                0.008   elongation factor Tu GTP binding domain containing ...
TRIM47                0.008   tripartite motif-containing 47 
RUNDC2B               0.008   RUN domain containing 2B 
LOC100131381          0.006   PREDICTED: hypothetical protein 
LOC100131381          0.006   PREDICTED: hypothetical protein 
LOC649201             0.006   PREDICTED: similar to paraneoplastic antigen MA1 [H...
SPEN                  0.006   spen homolog, transcriptional regulator 
KIAA1217              0.006   sickle tail isoform 3 
KIAA1217              0.006   sickle tail isoform 2 
KIAA1217              0.006   sickle tail isoform 1 
GLS                   0.006   glutaminase 
PCCB                  0.006   propionyl Coenzyme A carboxylase, beta polypeptide ...
SMTN                  0.006   smoothelin isoform b 
BRWD2                 0.006   bromodomain and WD repeat domain containing 2 
SMTN                  0.006   smoothelin isoform c 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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