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Search of human proteins with 6912444
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912444 potassium voltage-gated channel, subfamily G, member
2 [Homo sapiens]
(466 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912444 potassium voltage-gated channel, subfamily G, member ... 928 0.0
gi|27436988 potassium voltage-gated channel, subfamily G, member... 510 e-144
gi|27436996 potassium voltage-gated channel, subfamily G, member... 504 e-143
gi|27436993 potassium voltage-gated channel, subfamily G, member... 333 2e-91
gi|19071574 potassium voltage-gated channel, subfamily G, member... 333 3e-91
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 325 5e-89
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 315 4e-86
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 287 2e-77
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 273 3e-73
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 257 2e-68
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 254 1e-67
gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens] 253 2e-67
gi|20070166 potassium voltage-gated channel, subfamily F, member... 244 9e-65
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 235 7e-62
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 225 6e-59
gi|163792201 Shaw-related voltage-gated potassium channel protei... 225 6e-59
gi|24497460 Shaw-related voltage-gated potassium channel protein... 218 1e-56
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 211 9e-55
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 211 9e-55
gi|24497458 Shaw-related voltage-gated potassium channel protein... 210 3e-54
gi|21217561 Shaw-related voltage-gated potassium channel protein... 209 3e-54
gi|21217563 Shaw-related voltage-gated potassium channel protein... 209 3e-54
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 207 2e-53
gi|88758576 Shaw-related voltage-gated potassium channel protein... 205 8e-53
gi|24497462 Shaw-related voltage-gated potassium channel protein... 205 8e-53
gi|24497464 Shaw-related voltage-gated potassium channel protein... 205 8e-53
gi|25952092 potassium voltage-gated channel, shaker-related subf... 199 4e-51
gi|119395748 potassium voltage-gated channel subfamily A member ... 194 1e-49
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 193 2e-49
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 191 1e-48
>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
[Homo sapiens]
Length = 466
Score = 928 bits (2399), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MEPWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCD 60
MEPWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCD
Sbjct: 1 MEPWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCD 60
Query: 61 DYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCL 120
DYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCL
Sbjct: 61 DYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCL 120
Query: 121 RRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFA 180
RRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFA
Sbjct: 121 RRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFA 180
Query: 181 CVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQA 240
CVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQA
Sbjct: 181 CVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQA 240
Query: 241 ESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMR 300
ESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMR
Sbjct: 241 ESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMR 300
Query: 301 LARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASY 360
LARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASY
Sbjct: 301 LARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASY 360
Query: 361 WWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ 420
WWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ
Sbjct: 361 WWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ 420
Query: 421 RAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR 466
RAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR
Sbjct: 421 RAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSADALWVRAGR 466
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 510 bits (1313), Expect = e-144
Identities = 264/416 (63%), Positives = 321/416 (77%), Gaps = 9/416 (2%)
Query: 15 RARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRS 74
R R +IINVGG + L W L PL RL +L+AC DD+L VCDDYDV+ +EFFFDR+
Sbjct: 61 RRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRN 120
Query: 75 PCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEAR 134
P AF I+ LRAGKLRLLR CAL+F++EL YWGI E L+ CC RR ++ EE AE
Sbjct: 121 PGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMV 180
Query: 135 AGPTERGAQGSPAR-ALGP---RGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVT 190
E A S R + GP GRL R RRLRD+V+ PHSGL GK+FAC+SV FV VT
Sbjct: 181 EREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVT 240
Query: 191 AVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAP 250
AV L +ST+P +R EEE+G CS C ++F++E+VCV WFS EFLLR +QA SK AFLR+P
Sbjct: 241 AVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSP 300
Query: 251 LNIIDILALLPFYVSLLL-GLAAG---PG-GTKLLERAGLVLRLLRALRVLYVMRLARHS 305
L +ID++A+LP+Y++LL+ G AAG PG G L++ GLVLR+LRALR+LYVMRLARHS
Sbjct: 301 LTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHS 360
Query: 306 LGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVI 365
LGL++LGLT RRC REFGLLLLFLCVA+ALFAPL+++ E E+ +F+S+PA YWWAVI
Sbjct: 361 LGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVI 420
Query: 366 SMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQR 421
+MTTVGYGDMVPRS PGQVVALSSILSGILLMAFPVTSIFHTFSRSY ELK++Q+R
Sbjct: 421 TMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQER 476
>gi|27436996 potassium voltage-gated channel, subfamily G, member 4
[Homo sapiens]
Length = 519
Score = 504 bits (1298), Expect = e-143
Identities = 252/412 (61%), Positives = 316/412 (76%), Gaps = 7/412 (1%)
Query: 17 RHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPC 76
+ ++INVGG R L W+ L R PL+RL +LR CR +++++++CDDYD EFFFDRSP
Sbjct: 59 KEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPS 118
Query: 77 AFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARAG 136
AF IV+ L AGKL LL+ CAL+F++ELAYWGI+EA LERCCLR+L R+ EE E
Sbjct: 119 AFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKL 178
Query: 137 PTER--GAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGL 194
E Q R R RLR++V+NP SGL GK+FAC+S+ FVA TAV L
Sbjct: 179 HREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVSL 238
Query: 195 CLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNII 254
C+STMPD+RAEE++GECS KC +F++ET+CVAWFS EF LR +QA+ KC F + PLNII
Sbjct: 239 CVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNII 298
Query: 255 DILALLPFYVSLLLGL-----AAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLR 309
DILA+ P+YVSL + P G+ LE+ GLVLR+LRALR+LYVMRLARHSLGL+
Sbjct: 299 DILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQ 358
Query: 310 SLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTT 369
+LGLT+RRC REFGLLLLFL VA+ LF+PLV++AE+E G +F+S+PASYWWA+ISMTT
Sbjct: 359 TLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAIISMTT 418
Query: 370 VGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQR 421
VGYGDMVPRS+PGQ+VALSSILSGIL+MAFP TSIFHTFS SY ELK++Q++
Sbjct: 419 VGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQ 470
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 333 bits (855), Expect = 2e-91
Identities = 180/425 (42%), Positives = 265/425 (62%), Gaps = 29/425 (6%)
Query: 12 GGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFF 71
G + A V++NVGG R L+ L PL R+ RL CR D+L VCDDYD R+E+FF
Sbjct: 4 GRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFF 63
Query: 72 DRSPCAFRAIVALLRA-GKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRR---- 126
DR AF I+ +R GKLR C L+F +E+ YWG++ A LE CC RRL R
Sbjct: 64 DRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDT 123
Query: 127 ------EEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFA 180
+E R GA+ +P+R R R+R + P S LA ++ A
Sbjct: 124 YTFYSADEPGVLGRDEARPGGAEAAPSR---------RWLERMRRTFEEPTSSLAAQILA 174
Query: 181 CVSVSFVAVTAVGLCLSTMPDIR-AEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQ 239
VSV FV V+ V LC ST+PD R A + + R ++E +C+ WF+ E ++R +
Sbjct: 175 SVSVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSR---IIEAICIGWFTAECIVRFIV 231
Query: 240 AESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVM 299
+++KC F++ PLNIID+LA+ P+Y+S+L+ + G L+RAG+ LR+LR +R+ +V+
Sbjct: 232 SKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQ--LQRAGVTLRVLRMMRIFWVI 289
Query: 300 RLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELG---ARRDFSSV 356
+LARH +GL++LGLT++RC RE +LL+F+CVAMA+F+ L L E L + +DF+S+
Sbjct: 290 KLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSI 349
Query: 357 PASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELK 416
PA+ WW +ISMTTVGYGDM P ++PG+++ ++SGI+L+A P+T I+H+F + Y ELK
Sbjct: 350 PAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELK 409
Query: 417 EQQQR 421
+ R
Sbjct: 410 FRSAR 414
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 333 bits (853), Expect = 3e-91
Identities = 180/433 (41%), Positives = 264/433 (60%), Gaps = 34/433 (7%)
Query: 12 GGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFF 71
G + A V++NVGG R L+ L PL R+ RL CR D+L VCDDYD R+E+FF
Sbjct: 4 GRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFF 63
Query: 72 DRSPCAFRAIVALLRA-GKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRR---- 126
DR AF I+ +R GKLR C L+F +E+ YWG++ A LE CC RRL R
Sbjct: 64 DRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDT 123
Query: 127 ------EEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFA 180
+E R GA+ +P+R R R+R + P S LA ++ A
Sbjct: 124 YTFYSADEPGVLGRDEARPGGAEAAPSR---------RWLERMRRTFEEPTSSLAAQILA 174
Query: 181 CVSVSFVAVTAVGLCLSTMPDIRA---------EEERGECSPKCRSLFVLETVCVAWFSF 231
VSV FV V+ V LC ST+PD R + R P ++E +C+ WF+
Sbjct: 175 SVSVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTA 234
Query: 232 EFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLR 291
E ++R + +++KC F++ PLNIID+LA+ P+Y+S+L+ + G L+RAG+ LR+LR
Sbjct: 235 ECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQ--LQRAGVTLRVLR 292
Query: 292 ALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELG--- 348
+R+ +V++LARH +GL++LGLT++RC RE +LL+F+CVAMA+F+ L L E L
Sbjct: 293 MMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLET 352
Query: 349 ARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTF 408
+ +DF+S+PA+ WW +ISMTTVGYGDM P ++PG+++ ++SGI+L+A P+T I+H+F
Sbjct: 353 SNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSF 412
Query: 409 SRSYSELKEQQQR 421
+ Y ELK + R
Sbjct: 413 VQCYHELKFRSAR 425
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 325 bits (833), Expect = 5e-89
Identities = 167/409 (40%), Positives = 257/409 (62%), Gaps = 10/409 (2%)
Query: 14 TRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDR 73
T +R V INVGG + W L R P RL +LR C H+ LL VCDDY+++ +E+FFDR
Sbjct: 32 TCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDR 91
Query: 74 SPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAE- 132
P AF +I+ R GKL ++ CAL+F EL YWGIDE LE CC R +++E+ E
Sbjct: 92 HPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEE 151
Query: 133 -ARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTA 191
R T R +G R++L D+++ P+S +A K+ A VS+ F+ ++
Sbjct: 152 LRREAETMREREGEEF----DNTCCPDKRKKLWDLLEKPNSSVAAKILAIVSILFIVLST 207
Query: 192 VGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPL 251
+ L L+T+P+++ +E G+ + R L +E VC+AWF+ E+LLR L + +K F + PL
Sbjct: 208 IALSLNTLPELQETDEFGQLNDN-RQLAHVEAVCIAWFTMEYLLRFLSSPNKWKFFKGPL 266
Query: 252 NIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSL 311
N+ID+LA+LP+YV++ L + V+++ R +R+L +++LARHS GL+SL
Sbjct: 267 NVIDLLAILPYYVTIF--LTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSL 324
Query: 312 GLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVG 371
G T+RR E GLL+LFL + + +F+ LV AE++ A + F+S+PAS+WWA I+MTTVG
Sbjct: 325 GFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDATK-FTSIPASFWWATITMTTVG 383
Query: 372 YGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ 420
YGD+ P++L G++V ++G+L++A P+ I + FS Y E K Q++
Sbjct: 384 YGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEK 432
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 315 bits (808), Expect = 4e-86
Identities = 163/407 (40%), Positives = 250/407 (61%), Gaps = 10/407 (2%)
Query: 16 ARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSP 75
+R V +NVGG + W L R P RL +LR C HD LL VCDDY + +E+FFDR P
Sbjct: 30 SRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHP 89
Query: 76 CAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAE--A 133
AF +I+ R G+L ++ CAL+F EL YWGIDE LE CC R +++E+ E
Sbjct: 90 GAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQARYHQKKEQMNEELK 149
Query: 134 RAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVG 193
R T R +G R++L D+++ P+S +A K+ A +S+ F+ ++ +
Sbjct: 150 REAETLREREGEEF----DNTCCAEKRKKLWDLLEKPNSSVAAKILAIISIMFIVLSTIA 205
Query: 194 LCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNI 253
L L+T+P++++ +E G+ S L +E VC+AWF+ E+LLR L + K F + PLN
Sbjct: 206 LSLNTLPELQSLDEFGQ-STDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKWKFFKGPLNA 264
Query: 254 IDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGL 313
ID+LA+LP+YV++ L + V+++ R +R+L +++LARHS GL+SLG
Sbjct: 265 IDLLAILPYYVTIF--LTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGF 322
Query: 314 TMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYG 373
T+RR E GLL+LFL + + +F+ LV AE++ + F S+PAS+WWA I+MTTVGYG
Sbjct: 323 TLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTK-FKSIPASFWWATITMTTVGYG 381
Query: 374 DMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ 420
D+ P++L G++V ++G+L++A P+ I + FS Y E K Q++
Sbjct: 382 DIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEK 428
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 287 bits (734), Expect = 2e-77
Identities = 174/462 (37%), Positives = 247/462 (53%), Gaps = 27/462 (5%)
Query: 8 PGGGGGTRARH----VIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYD 63
PG G R R + +NVGG R +L+ ALAR P RL RL+A + R+CDDYD
Sbjct: 37 PGPDTGIRWRRSDEALRVNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYD 96
Query: 64 VSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRL 123
+ EF+FDR P F +++ R G L +L C AF E YWG+ E L CC R
Sbjct: 97 EAAREFYFDRHPGFFLSLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARY 156
Query: 124 RRREEEAAEARAGPTERGAQGSPA--------RALGPRG--RLQRGRRRLRDVVDNPHSG 173
R A ++ + P R L G R R RRRL ++NP
Sbjct: 157 LERRLTQPHAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYS 216
Query: 174 LAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRS-----------LFVLE 222
L KLF+CVS+S V + +C+ ++P+ +A E + L LE
Sbjct: 217 LPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLE 276
Query: 223 TVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLER 282
C+AWFSFE R L A S F PLN+IDI+++LPFY++LL G+A G G K
Sbjct: 277 YFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGKEFGH 336
Query: 283 AGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHL 342
G V+++ R +R+ V++LARHS GLRSLG T++ RE G+LLL+L V +++F+ + +
Sbjct: 337 LGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYT 396
Query: 343 AERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVT 402
AE+E F+++PA +WW +SMTTVGYGD+VP ++ G++ A IL GIL++A P+T
Sbjct: 397 AEKEEDV--GFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPIT 454
Query: 403 SIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSS 444
IF+ FS Y K + + ED S ++S
Sbjct: 455 IIFNKFSHFYRRQKALEAAVRNSNHQEFEDLLSSIDGVSEAS 496
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 273 bits (697), Expect = 3e-73
Identities = 163/431 (37%), Positives = 250/431 (58%), Gaps = 26/431 (6%)
Query: 21 INVGGCRVRLAWAALARCPLARLERLR----------ACRGHDDLLRVCDDYDVSRDEFF 70
+NVGG R L+ AL+ P RL +L A L +CDD + +E+F
Sbjct: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
Query: 71 FDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREE-- 128
FDRS AFR ++ R G+L ++ CAL+F E+ YWGIDE ++ CC R RR+E
Sbjct: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELS 162
Query: 129 EAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVA 188
E + + ++ +Q + +G R++L ++++ P S A ++F +S+ FV
Sbjct: 163 ETLDFKKDTEDQESQHESEQDFS-QGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVV 221
Query: 189 VTAVGLCLSTMPDIRAEEERGECS-PKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFL 247
V+ + + L + E S + L +LE VC++WF+ EF+LR L +C FL
Sbjct: 222 VSIINMALMS----------AELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFL 271
Query: 248 RAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLG 307
R NIID+LA+LPFY++LL+ +G T+ LE G ++++LR LR L +++L RHS G
Sbjct: 272 RKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTG 331
Query: 308 LRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISM 367
LRSLG+T+ +C E GLLLLFL V +++F+ + + AE+ + F+SVP ++WWA SM
Sbjct: 332 LRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSI-PDTTFTSVPCAWWWATTSM 390
Query: 368 TTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEP 427
TTVGYGD+ P + G++VA ILSGIL++A P+ I FS Y LK ++ A
Sbjct: 391 TTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLK-LKEAAVRQRE 449
Query: 428 ALQEDSTHSAT 438
AL++ + + AT
Sbjct: 450 ALKKLTKNIAT 460
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 257 bits (656), Expect = 2e-68
Identities = 147/409 (35%), Positives = 238/409 (58%), Gaps = 17/409 (4%)
Query: 19 VIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAF 78
V +NVGG + + + L R P RL +L C + +L +CDDY V+ E++FDR+P F
Sbjct: 17 VNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSEEAILELCDDYSVADKEYYFDRNPSLF 76
Query: 79 RAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAE------ 132
R ++ GKL ++ C +F E+ YWGI+E ++ CC R + R+EE E
Sbjct: 77 RYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQK 136
Query: 133 ARAGPTERGAQGSP--ARALGPRGRLQRG--RRRLRDVVDNPHSGLAGKLFACVSVSFVA 188
+ T+ + S + L L+ G R+++ ++NP L+ KL A S+S V
Sbjct: 137 SHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIAISSLSVVL 196
Query: 189 VTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLR 248
+ V +C+ +M + + E+ GE L +E C+AWF+ E +R A + F +
Sbjct: 197 ASIVAMCVHSMSEFQNED--GEVDDPV--LEGVEIACIAWFTGELAVRLAAAPCQKKFWK 252
Query: 249 APLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGL 308
PLNIID ++++PFY +L + ++ +E G V+++LR +R+ +++LARHS+GL
Sbjct: 253 NPLNIIDFVSIIPFYATLAVDTKEEE--SEDIENMGKVVQILRLMRIFRILKLARHSVGL 310
Query: 309 RSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMT 368
RSLG T+R E GLLLLFL V +++F+ L++ E++ +S+P +WWA ISMT
Sbjct: 311 RSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKD-DHTSSLTSIPICWWWATISMT 369
Query: 369 TVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKE 417
TVGYGD P +L G+++A + I+ GIL++A P+T IF+ FS+ Y + K+
Sbjct: 370 TVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKD 418
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 254 bits (649), Expect = 1e-67
Identities = 143/419 (34%), Positives = 232/419 (55%), Gaps = 25/419 (5%)
Query: 21 INVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRA 80
INVGG + RL L R P RL RL C + +L +CDDYD + EF+FDR+P F
Sbjct: 21 INVGGFKRRLRSHTLLRFPETRLGRLLLCHSREAILELCDDYDDVQREFYFDRNPELFPY 80
Query: 81 IVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARAGPTER 140
++ GKL ++ C +F E+ YWGI+E ++ CC R+ E + + E+
Sbjct: 81 VLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKW--DEQ 138
Query: 141 GAQGSPARALG---------------PRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVS 185
Q S + P G RR+L +DNP + ++F+ +S+
Sbjct: 139 SDQESTTSSFDEILAFYNDASKFDGQPLGNF---RRQLWLALDNPGYSVLSRVFSILSIL 195
Query: 186 FVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCA 245
V + + +CL+++PD + + +G R ++E +AWF+FE + R A
Sbjct: 196 VVMGSIITMCLNSLPDFQIPDSQGNPGEDPR-FEIVEHFGIAWFTFELVARFAVAPDFLK 254
Query: 246 FLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHS 305
F + LN+ID+++++PFY++L++ L T L G V ++LR +R+ +++LARHS
Sbjct: 255 FFKNALNLIDLMSIVPFYITLVVNLVV--ESTPTLANLGRVAQVLRLMRIFRILKLARHS 312
Query: 306 LGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVI 365
GLRSLG T++ +E GLLLL+L V +++F+ + + E+E +++PA +WWA +
Sbjct: 313 TGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKE--ENEGLATIPACWWWATV 370
Query: 366 SMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAAS 424
SMTTVGYGD+VP + G++ A + IL+GIL++ P+T IF+ FS Y K+ + S
Sbjct: 371 SMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRS 429
>gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]
Length = 545
Score = 253 bits (647), Expect = 2e-67
Identities = 143/411 (34%), Positives = 226/411 (54%), Gaps = 22/411 (5%)
Query: 21 INVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRA 80
+NVGG +L + LA P RL RL L +CDDY+ DE+FFDR P F+
Sbjct: 101 VNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQLSLCDDYEEQTDEYFFDRDPAVFQL 160
Query: 81 IVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAE-------- 132
+ +G L +L G C F +EL YWG+ RCC R +E +E
Sbjct: 161 VYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYTPRCCRICFEERRDELSERLKIQHEL 220
Query: 133 -ARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTA 191
A+A E R GP+ RRRL ++++ P S +A K S +FV V+
Sbjct: 221 RAQAQVEEAEELFRDMRFYGPQ------RRRLWNLMEKPFSSVAAKAIGVASSTFVLVSV 274
Query: 192 VGLCLSTMPDIRAEEERGECSPKCRSLFV-LETVCVAWFSFEFLLRSLQAESKCAFLRAP 250
V L L+T+ +++ +GE P R + +E +C+ +F+ E+LLR F R+
Sbjct: 275 VALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTLEYLLRLASTPDLRRFARSA 334
Query: 251 LNIIDILALLPFYVSLLLGLAAGPGGTK-----LLERAGLVLRLLRALRVLYVMRLARHS 305
LN++D++A+LP Y+ LLL G G + + + G VLR++R +R+ +++LARHS
Sbjct: 335 LNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQVLRVMRLMRIFRILKLARHS 394
Query: 306 LGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVI 365
GLR+ G T+R+C ++ G LLLF+ + + F+ V+ E ++ + +F+++P S+WWA +
Sbjct: 395 TGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHDVPS-TNFTTIPHSWWWAAV 453
Query: 366 SMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELK 416
S++TVGYGDM P + G+ A I GI+L P++ +++ FS YS+LK
Sbjct: 454 SISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNKFSDYYSKLK 504
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 244 bits (624), Expect = 9e-65
Identities = 144/444 (32%), Positives = 246/444 (55%), Gaps = 16/444 (3%)
Query: 19 VIINVGGCRVRLAWAALARCPLARLERLRACR--GHDDLLRVCDDYDVSRDEFFFDRSPC 76
+++NVGG R L L++ P RL L C G+D + +CDDYD + EF+FDR P
Sbjct: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 84
Query: 77 AFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAE-ARA 135
AF+ ++ + G++ + +G C + F++E+ +W +D L+ CC L + EE E AR
Sbjct: 85 AFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARR 144
Query: 136 GPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLC 195
G A GR +R ++ + ++ P S ++ A +S + V++V +C
Sbjct: 145 VQLILDDLGVDA----AEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMC 200
Query: 196 LSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIID 255
+ T+P+++ + G + +L +ET C+ WF+ E+LLR + +K F + +NI+D
Sbjct: 201 MGTIPELQVLDAEGN-RVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVD 259
Query: 256 ILALLPFYVSLLLGLAAGPGGTKLLERAGL--VLRLLRALRVLYVMRLARHSLGLRSLGL 313
+LA+LPFYVSL L G +++E + ++ LR +R+ + +LARHS GL++L
Sbjct: 260 VLAILPFYVSLTLTHL----GARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTY 315
Query: 314 TMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYG 373
++R +E GLLL++L V + +F+ L + E+ F S+P S+WWA+I+MTTVGYG
Sbjct: 316 ALKRSFKELGLLLMYLAVGIFVFSALGYTMEQS-HPETLFKSIPQSFWWAIITMTTVGYG 374
Query: 374 DMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDS 433
D+ P++ G++ A S L G++ +A P+ I + F R Y++ + + AA E L E +
Sbjct: 375 DIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNK-QRVLETAAKHELELMELN 433
Query: 434 THSATATEDSSQGPDSAGLADDSA 457
+ S + D L + A
Sbjct: 434 SSSGGEGKTGGSRSDLDNLPPEPA 457
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 235 bits (599), Expect = 7e-62
Identities = 155/473 (32%), Positives = 236/473 (49%), Gaps = 39/473 (8%)
Query: 2 EPWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDD 61
+P P +PG +++NV G R L R P D LL +
Sbjct: 25 QPLPPAPGVKASRGDEVLVVNVSGRRFETWKNTLDRYP-------------DTLLGSSEK 71
Query: 62 ---YDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERC 118
YD E+FFDR P FR ++ R G+L R C AF +ELA++G+ + C
Sbjct: 72 EFFYDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDC 131
Query: 119 CLRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKL 178
CL R R++E AE R E Q AL L R+RL +NPH+ A +
Sbjct: 132 CLEEYRDRKKENAE-RLAEDEEAEQAGDGPALPAGSSL---RQRLWRAFENPHTSTAALV 187
Query: 179 FACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKC-----RSLFVLETVCVAWFSFEF 233
F V+ F+AV+ + + T+P R R C ++ F ++T CV F+ E+
Sbjct: 188 FYYVTGFFIAVSVIANVVETIP-CRGSARRSSREQPCGERFPQAFFCMDTACVLIFTGEY 246
Query: 234 LLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRAL 293
LLR A S+C FLR+ +++ID++A+LP+Y+ LL+ G + LR
Sbjct: 247 LLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVPKNDDVSGAFVT---------LRVF 297
Query: 294 RVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDF 353
RV + + +RHS GLR LG T++ CA E G LL L +A+ +FA ++ AE+ + +F
Sbjct: 298 RVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTN-KTNF 356
Query: 354 SSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYS 413
+S+PA++W+ +++MTT+GYGDMVP ++ G++ LSG+L++A PV I FSR Y
Sbjct: 357 TSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYH 416
Query: 414 ELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDSAGLADDSA---DALWVR 463
+ + +R A + L + T Q + GL D + AL VR
Sbjct: 417 QNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNGGLEDSGSGEEQALCVR 469
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 225 bits (574), Expect = 6e-59
Identities = 151/460 (32%), Positives = 225/460 (48%), Gaps = 60/460 (13%)
Query: 11 GGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFF 70
G G + ++INVGG R + + L P RL L H DYD DEFF
Sbjct: 2 GQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHF-----DYDPRADEFF 56
Query: 71 FDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLR--RREE 128
FDR P F I+ R GKL C + +ELA+WGIDE +E CC R R E
Sbjct: 57 FDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAE 116
Query: 129 EAAEARAG-PTERGAQGSPARALG------------------------PRGRLQRGRRRL 163
EA ++ G P + A + A G P G +R + R+
Sbjct: 117 EALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRI 176
Query: 164 RDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDI-----RAEEERGECSPKCRS- 217
+ ++P+S + A S+ F+ V+ CL T + E E + R
Sbjct: 177 WALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYY 236
Query: 218 --------LFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLG 269
L +E VCV WF+FEFL+R + +K F++ LNIID +A+LPFY+ + L
Sbjct: 237 REAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLS 296
Query: 270 LAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFL 329
+ +L LR++R +R+L + +L RH +GLR LG T+R EF LL++FL
Sbjct: 297 GLSSKAAKDVLG----FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFL 352
Query: 330 CVAMALFAPLVHLAERELGARRD---------FSSVPASYWWAVISMTTVGYGDMVPRSL 380
+ + +FA +++ AER +GA+ + F ++P +WWAV++MTT+GYGDM P++
Sbjct: 353 ALGVLIFATMIYYAER-IGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTW 411
Query: 381 PGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ 420
G +V L+G+L +A PV I + F YS +Q+
Sbjct: 412 SGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQK 451
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 225 bits (574), Expect = 6e-59
Identities = 151/460 (32%), Positives = 225/460 (48%), Gaps = 60/460 (13%)
Query: 11 GGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFF 70
G G + ++INVGG R + + L P RL L H DYD DEFF
Sbjct: 2 GQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHF-----DYDPRADEFF 56
Query: 71 FDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLR--RREE 128
FDR P F I+ R GKL C + +ELA+WGIDE +E CC R R E
Sbjct: 57 FDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAE 116
Query: 129 EAAEARAG-PTERGAQGSPARALG------------------------PRGRLQRGRRRL 163
EA ++ G P + A + A G P G +R + R+
Sbjct: 117 EALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRI 176
Query: 164 RDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDI-----RAEEERGECSPKCRS- 217
+ ++P+S + A S+ F+ V+ CL T + E E + R
Sbjct: 177 WALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYY 236
Query: 218 --------LFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLG 269
L +E VCV WF+FEFL+R + +K F++ LNIID +A+LPFY+ + L
Sbjct: 237 REAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLS 296
Query: 270 LAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFL 329
+ +L LR++R +R+L + +L RH +GLR LG T+R EF LL++FL
Sbjct: 297 GLSSKAAKDVLG----FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFL 352
Query: 330 CVAMALFAPLVHLAERELGARRD---------FSSVPASYWWAVISMTTVGYGDMVPRSL 380
+ + +FA +++ AER +GA+ + F ++P +WWAV++MTT+GYGDM P++
Sbjct: 353 ALGVLIFATMIYYAER-IGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTW 411
Query: 381 PGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ 420
G +V L+G+L +A PV I + F YS +Q+
Sbjct: 412 SGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQK 451
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 218 bits (554), Expect = 1e-56
Identities = 158/501 (31%), Positives = 224/501 (44%), Gaps = 95/501 (18%)
Query: 2 EPWPCSPG------GGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDL 55
EP P P GGGG + ++INVGG R + L P RL L
Sbjct: 67 EPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARF 126
Query: 56 LRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARL 115
DYD DEFFFDR P F ++ R GKL C F +EL +WGIDE +
Sbjct: 127 -----DYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDV 181
Query: 116 ERCCLRRLR--RREEEAAEARAGPTERGAQ------------------------------ 143
E CC R R EEA ++ P GA
Sbjct: 182 EACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGE 241
Query: 144 --------------GSPARALGPRGRL-QRGRRRLRDVVDNPHSGLAGKLFACVSVSFVA 188
G P A G G +R + R+ + ++P+S A + A S+ F+
Sbjct: 242 LKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFIL 301
Query: 189 VTAVGLCLST--------------------MPDIRAEEERGECSPKCRSLFVLETVCVAW 228
++ CL T P E P L +E VCV W
Sbjct: 302 ISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEP---FLTYVEGVCVVW 358
Query: 229 FSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLR 288
F+FEFL+R K FL++ LNIID +A+LPFY+ + L + +L LR
Sbjct: 359 FTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLG----FLR 414
Query: 289 LLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELG 348
++R +R+L + +L RH +GLR LG T+R EF LL++FL + + +FA +++ AER +G
Sbjct: 415 VVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAER-IG 473
Query: 349 ARRD---------FSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAF 399
A D F ++P +WWAV++MTT+GYGDM P++ G +V L+G+L +A
Sbjct: 474 ADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAM 533
Query: 400 PVTSIFHTFSRSYSELKEQQQ 420
PV I + F YS +Q+
Sbjct: 534 PVPVIVNNFGMYYSLAMAKQK 554
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 211 bits (538), Expect = 9e-55
Identities = 134/434 (30%), Positives = 219/434 (50%), Gaps = 39/434 (8%)
Query: 3 PWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDD- 61
P P +P + +++NV G R + L R P D LL +
Sbjct: 26 PMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYP-------------DTLLGSTEKE 72
Query: 62 --YDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC 119
++ E+FFDR P FR ++ R GKL R C A+ DELA++GI + CC
Sbjct: 73 FFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCC 132
Query: 120 LRRLRRREEEAAEARA--GPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGK 177
+ R+ E AE +E + P+ + R+ + +NPH+
Sbjct: 133 YEEYKDRKRENAERLMDDNDSENNQESMPSLSF---------RQTMWRAFENPHTSTLAL 183
Query: 178 LFACVSVSFVAVTAVGLCLSTMP--DIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLL 235
+F V+ F+AV+ + + T+P + +E + F L+T CV F+ E+LL
Sbjct: 184 VFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLL 243
Query: 236 RSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRV 295
R A S+ F+R+ ++IID++A++P+Y+ L++ G + LR RV
Sbjct: 244 RLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVT---------LRVFRV 294
Query: 296 LYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSS 355
+ + +RHS GLR LG T++ CA E G LL L +A+ +FA ++ AE+ A + F+S
Sbjct: 295 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASK-FTS 353
Query: 356 VPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSEL 415
+PAS+W+ +++MTT+GYGDMVP+++ G++ LSG+L++A PV I FSR Y +
Sbjct: 354 IPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQN 413
Query: 416 KEQQQRAASPEPAL 429
+ +R A + L
Sbjct: 414 QRADKRRAQKKARL 427
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 211 bits (538), Expect = 9e-55
Identities = 134/434 (30%), Positives = 219/434 (50%), Gaps = 39/434 (8%)
Query: 3 PWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDD- 61
P P +P + +++NV G R + L R P D LL +
Sbjct: 26 PMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYP-------------DTLLGSTEKE 72
Query: 62 --YDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC 119
++ E+FFDR P FR ++ R GKL R C A+ DELA++GI + CC
Sbjct: 73 FFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCC 132
Query: 120 LRRLRRREEEAAEARA--GPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGK 177
+ R+ E AE +E + P+ + R+ + +NPH+
Sbjct: 133 YEEYKDRKRENAERLMDDNDSENNQESMPSLSF---------RQTMWRAFENPHTSTLAL 183
Query: 178 LFACVSVSFVAVTAVGLCLSTMP--DIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLL 235
+F V+ F+AV+ + + T+P + +E + F L+T CV F+ E+LL
Sbjct: 184 VFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGERYSVAFFCLDTACVMIFTVEYLL 243
Query: 236 RSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRV 295
R A S+ F+R+ ++IID++A++P+Y+ L++ G + LR RV
Sbjct: 244 RLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFVT---------LRVFRV 294
Query: 296 LYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSS 355
+ + +RHS GLR LG T++ CA E G LL L +A+ +FA ++ AE+ A + F+S
Sbjct: 295 FRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASK-FTS 353
Query: 356 VPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSEL 415
+PAS+W+ +++MTT+GYGDMVP+++ G++ LSG+L++A PV I FSR Y +
Sbjct: 354 IPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQN 413
Query: 416 KEQQQRAASPEPAL 429
+ +R A + L
Sbjct: 414 QRADKRRAQKKARL 427
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 210 bits (534), Expect = 3e-54
Identities = 139/447 (31%), Positives = 219/447 (48%), Gaps = 64/447 (14%)
Query: 68 EFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRR- 126
EFFFDR P F ++ R GKL C F +ELA+WGIDE +E CC R+
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHR 160
Query: 127 ---------------------EEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRD 165
+E+ A R G + G P G GR +R + R+
Sbjct: 161 DAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPD---GKSGRWRRLQPRMWA 217
Query: 166 VVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFV----- 220
+ ++P+S A + A S+ F+ V+ CL T + + E S+ +
Sbjct: 218 LFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIE 277
Query: 221 -------LETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAG 273
+E VCV WF+FEFL+R + + +K F++ LNIID +A+LPFY+ + L +
Sbjct: 278 TDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSS 337
Query: 274 PGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAM 333
+L LR++R +R+L + +L RH +GLR LG T+R EF LL++FL + +
Sbjct: 338 KAAKDVLG----FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGV 393
Query: 334 ALFAPLVHLAERELGARRD---------FSSVPASYWWAVISMTTVGYGDMVPRSLPGQV 384
+FA +++ AER +GA+ + F ++P +WWAV++MTT+GYGDM P++ G +
Sbjct: 394 LIFATMIYYAER-VGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGML 452
Query: 385 VALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ-------------RAASPEPALQE 431
V L+G+L +A PV I + F YS +Q+ +A+SP E
Sbjct: 453 VGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQASSPTFCKTE 512
Query: 432 DSTHSATATEDSSQGPDSAGLADDSAD 458
+ + D+ G D+ L + +D
Sbjct: 513 LNMACNSTQSDTCLGKDNRLLEHNRSD 539
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 209 bits (533), Expect = 3e-54
Identities = 130/396 (32%), Positives = 202/396 (51%), Gaps = 51/396 (12%)
Query: 68 EFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRR- 126
EFFFDR P F ++ R GKL C F +ELA+WGIDE +E CC R+
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHR 160
Query: 127 ---------------------EEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRD 165
+E+ A R G + G P G GR +R + R+
Sbjct: 161 DAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPD---GKSGRWRRLQPRMWA 217
Query: 166 VVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFV----- 220
+ ++P+S A + A S+ F+ V+ CL T + + E S+ +
Sbjct: 218 LFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIE 277
Query: 221 -------LETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAG 273
+E VCV WF+FEFL+R + + +K F++ LNIID +A+LPFY+ + L +
Sbjct: 278 TDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSS 337
Query: 274 PGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAM 333
+L LR++R +R+L + +L RH +GLR LG T+R EF LL++FL + +
Sbjct: 338 KAAKDVLG----FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGV 393
Query: 334 ALFAPLVHLAERELGARRD---------FSSVPASYWWAVISMTTVGYGDMVPRSLPGQV 384
+FA +++ AER +GA+ + F ++P +WWAV++MTT+GYGDM P++ G +
Sbjct: 394 LIFATMIYYAER-VGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGML 452
Query: 385 VALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ 420
V L+G+L +A PV I + F YS +Q+
Sbjct: 453 VGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQK 488
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 209 bits (533), Expect = 3e-54
Identities = 130/396 (32%), Positives = 202/396 (51%), Gaps = 51/396 (12%)
Query: 68 EFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRR- 126
EFFFDR P F ++ R GKL C F +ELA+WGIDE +E CC R+
Sbjct: 101 EFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHR 160
Query: 127 ---------------------EEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRD 165
+E+ A R G + G P G GR +R + R+
Sbjct: 161 DAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPD---GKSGRWRRLQPRMWA 217
Query: 166 VVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFV----- 220
+ ++P+S A + A S+ F+ V+ CL T + + E S+ +
Sbjct: 218 LFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIE 277
Query: 221 -------LETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAG 273
+E VCV WF+FEFL+R + + +K F++ LNIID +A+LPFY+ + L +
Sbjct: 278 TDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSS 337
Query: 274 PGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAM 333
+L LR++R +R+L + +L RH +GLR LG T+R EF LL++FL + +
Sbjct: 338 KAAKDVLG----FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGV 393
Query: 334 ALFAPLVHLAERELGARRD---------FSSVPASYWWAVISMTTVGYGDMVPRSLPGQV 384
+FA +++ AER +GA+ + F ++P +WWAV++MTT+GYGDM P++ G +
Sbjct: 394 LIFATMIYYAER-VGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGML 452
Query: 385 VALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQ 420
V L+G+L +A PV I + F YS +Q+
Sbjct: 453 VGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQK 488
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 207 bits (527), Expect = 2e-53
Identities = 132/417 (31%), Positives = 211/417 (50%), Gaps = 35/417 (8%)
Query: 19 VIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDD---YDVSRDEFFFDRSP 75
+++NV G R + L R P D LL + Y ++FFDR P
Sbjct: 43 IVLNVSGTRFQTWQDTLERYP-------------DTLLGSSERDFFYHPETQQYFFDRDP 89
Query: 76 CAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARA 135
FR I+ R GKL R C A+ +ELA++G+ + CC + R E AE
Sbjct: 90 DIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQ 149
Query: 136 GPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLC 195
+ G A R+R+ +NPH+ +F V+ F+AV+ +
Sbjct: 150 DDADTDTAGESALPT------MTARQRVWRAFENPHTSTMALVFYYVTGFFIAVSVIANV 203
Query: 196 LSTMPDIRAEEERGE--CSPKCR-SLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLN 252
+ T+P + E C + + F L+T CV F+ E+LLR A S+ F+R+ ++
Sbjct: 204 VETVPCGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYLLRLAAAPSRYRFVRSVMS 263
Query: 253 IIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLG 312
IID++A+LP+Y+ L++ G + LR RV + + +RHS GLR LG
Sbjct: 264 IIDVVAILPYYIGLVMTDNEDVSGAFVT---------LRVFRVFRIFKFSRHSQGLRILG 314
Query: 313 LTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGY 372
T++ CA E G LL L +A+ +FA ++ AE+ A + F+S+PA++W+ +++MTT+GY
Sbjct: 315 YTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASK-FTSIPAAFWYTIVTMTTLGY 373
Query: 373 GDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPAL 429
GDMVP+++ G++ LSG+L++A PV I FSR Y + + +R A + L
Sbjct: 374 GDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARL 430
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 205 bits (521), Expect = 8e-53
Identities = 155/496 (31%), Positives = 231/496 (46%), Gaps = 72/496 (14%)
Query: 13 GTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRD----- 67
G + +IINVGG R + L P RL L G D V
Sbjct: 32 GEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGR--PETDGGGVGSSGSSGG 89
Query: 68 ---EFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLR 124
EFFFDR P F ++ R GKL C F +EL +WGIDE +E CC R
Sbjct: 90 GGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYR 149
Query: 125 --RREEEAAEARAGPTERGAQGSPA------------RALGPR----------GRLQRGR 160
R EEA + P G+ P+ + LGP G + +
Sbjct: 150 QHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQ 209
Query: 161 RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLST---------------MPDIRAE 205
R+ + ++P+S A ++ A S+ F+ V+ CL T + +I +
Sbjct: 210 PRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSV 269
Query: 206 EERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVS 265
R E + L +E VCV WF+ EFL+R + F++ LNIID +A+LPFY+
Sbjct: 270 HFRREVETE-PILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLE 328
Query: 266 LLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLL 325
+ L + +L LR++R +R+L + +L RH +GLR LG T+R EF LL
Sbjct: 329 VGLSGLSSKAARDVLG----FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384
Query: 326 LLFLCVAMALFAPLVHLAERELGAR---------RDFSSVPASYWWAVISMTTVGYGDMV 376
++FL + + +FA +++ AER +GAR DF ++P +WWAV++MTT+GYGDM
Sbjct: 385 IIFLALGVLIFATMIYYAER-IGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMY 443
Query: 377 PRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ-----QRAASPEPALQE 431
P++ G +V L+G+L +A PV I + F YS +Q ++ P PA E
Sbjct: 444 PKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLE 503
Query: 432 DSTH---SATATEDSS 444
+ T+ DS+
Sbjct: 504 SPMYCKSEETSPRDST 519
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 205 bits (521), Expect = 8e-53
Identities = 155/496 (31%), Positives = 231/496 (46%), Gaps = 72/496 (14%)
Query: 13 GTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRD----- 67
G + +IINVGG R + L P RL L G D V
Sbjct: 32 GEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGR--PETDGGGVGSSGSSGG 89
Query: 68 ---EFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLR 124
EFFFDR P F ++ R GKL C F +EL +WGIDE +E CC R
Sbjct: 90 GGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYR 149
Query: 125 --RREEEAAEARAGPTERGAQGSPA------------RALGPR----------GRLQRGR 160
R EEA + P G+ P+ + LGP G + +
Sbjct: 150 QHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQ 209
Query: 161 RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLST---------------MPDIRAE 205
R+ + ++P+S A ++ A S+ F+ V+ CL T + +I +
Sbjct: 210 PRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSV 269
Query: 206 EERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVS 265
R E + L +E VCV WF+ EFL+R + F++ LNIID +A+LPFY+
Sbjct: 270 HFRREVETE-PILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLE 328
Query: 266 LLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLL 325
+ L + +L LR++R +R+L + +L RH +GLR LG T+R EF LL
Sbjct: 329 VGLSGLSSKAARDVLG----FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384
Query: 326 LLFLCVAMALFAPLVHLAERELGAR---------RDFSSVPASYWWAVISMTTVGYGDMV 376
++FL + + +FA +++ AER +GAR DF ++P +WWAV++MTT+GYGDM
Sbjct: 385 IIFLALGVLIFATMIYYAER-IGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMY 443
Query: 377 PRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ-----QRAASPEPALQE 431
P++ G +V L+G+L +A PV I + F YS +Q ++ P PA E
Sbjct: 444 PKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLE 503
Query: 432 DSTH---SATATEDSS 444
+ T+ DS+
Sbjct: 504 SPMYCKSEETSPRDST 519
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 205 bits (521), Expect = 8e-53
Identities = 155/496 (31%), Positives = 231/496 (46%), Gaps = 72/496 (14%)
Query: 13 GTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRD----- 67
G + +IINVGG R + L P RL L G D V
Sbjct: 32 GEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGR--PETDGGGVGSSGSSGG 89
Query: 68 ---EFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLR 124
EFFFDR P F ++ R GKL C F +EL +WGIDE +E CC R
Sbjct: 90 GGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYR 149
Query: 125 --RREEEAAEARAGPTERGAQGSPA------------RALGPR----------GRLQRGR 160
R EEA + P G+ P+ + LGP G + +
Sbjct: 150 QHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQ 209
Query: 161 RRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLST---------------MPDIRAE 205
R+ + ++P+S A ++ A S+ F+ V+ CL T + +I +
Sbjct: 210 PRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSV 269
Query: 206 EERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVS 265
R E + L +E VCV WF+ EFL+R + F++ LNIID +A+LPFY+
Sbjct: 270 HFRREVETE-PILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLE 328
Query: 266 LLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLL 325
+ L + +L LR++R +R+L + +L RH +GLR LG T+R EF LL
Sbjct: 329 VGLSGLSSKAARDVLG----FLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384
Query: 326 LLFLCVAMALFAPLVHLAERELGAR---------RDFSSVPASYWWAVISMTTVGYGDMV 376
++FL + + +FA +++ AER +GAR DF ++P +WWAV++MTT+GYGDM
Sbjct: 385 IIFLALGVLIFATMIYYAER-IGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMY 443
Query: 377 PRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQ-----QRAASPEPALQE 431
P++ G +V L+G+L +A PV I + F YS +Q ++ P PA E
Sbjct: 444 PKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLE 503
Query: 432 DSTH---SATATEDSS 444
+ T+ DS+
Sbjct: 504 SPMYCKSEETSPRDST 519
>gi|25952092 potassium voltage-gated channel, shaker-related
subfamily, member 7 [Homo sapiens]
Length = 456
Score = 199 bits (506), Expect = 4e-51
Identities = 149/449 (33%), Positives = 223/449 (49%), Gaps = 69/449 (15%)
Query: 1 MEPWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCD 60
MEP C P G R +++NV G R L R P L D R
Sbjct: 1 MEP-RCPPPCGCCER---LVLNVAGLRFETRARTLGRFPDTLL---------GDPARRGR 47
Query: 61 DYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCAL---AFRDELAYWGIDEARLER 117
YD +R E+FFDR +F A++ ++G LR P + F +E+A++G+ A L R
Sbjct: 48 FYDDARREYFFDRHRPSFDAVLYYYQSGGR--LRRPAHVPLDVFLEEVAFYGLGAAALAR 105
Query: 118 CCLRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGK 177
RE+E P ER P RA R+L + + P S A +
Sbjct: 106 L-------REDEGCPV---PPERPL---PRRAFA---------RQLWLLFEFPESSQAAR 143
Query: 178 LFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRS-------------------- 217
+ A VSV + V+ V CL T+PD R + + + +
Sbjct: 144 VLAVVSVLVILVSIVVFCLETLPDFRDDRDGTGLAAAAAAGPFPAPLNGSSQMPGNPPRL 203
Query: 218 -----LFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAA 272
FV+ET+C+ WFSFE L+R L SK F + +N+ID +A+LP++V+L LA
Sbjct: 204 PFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVAILPYFVALGTELAR 263
Query: 273 GPG-GTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCV 331
G G + + A +LR++R +RV + +L+RHS GL+ LG T+R RE GLL+ FL +
Sbjct: 264 QRGVGQQAMSLA--ILRVIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFI 321
Query: 332 AMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSIL 391
+ LF+ V+ AE + F+S+P S+WWAV++MTTVGYGDM P ++ G++V +
Sbjct: 322 GVVLFSSAVYFAEVDR-VDSHFTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAI 380
Query: 392 SGILLMAFPVTSIFHTFSRSYSELKEQQQ 420
+G+L ++ PV I FS Y E ++
Sbjct: 381 AGVLTISLPVPVIVSNFSYFYHRETEGEE 409
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 194 bits (493), Expect = 1e-49
Identities = 136/449 (30%), Positives = 230/449 (51%), Gaps = 56/449 (12%)
Query: 19 VIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAF 78
V+IN+ G R LA+ P L + + +D R+E+FFDR+ +F
Sbjct: 39 VVINISGLRFETQLKTLAQFPNTLLGNPKKRMRY---------FDPLRNEYFFDRNRPSF 89
Query: 79 RAIVALLRAGKLRLLRGPCALA---FRDELAYWGIDEARLERCCLRRLRRREEEAAEARA 135
AI+ ++G LR P + F +E+ ++ + E +E+ RE+E
Sbjct: 90 DAILYYYQSGGR--LRRPVNVPLDMFSEEIKFYELGEEAMEKF-------REDE------ 134
Query: 136 GPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLC 195
G R L P QR ++ + + P S ++ A VSV + ++ V C
Sbjct: 135 -----GFIKEEERPL-PEKEYQR---QVWLLFEYPESSGPARVIAIVSVMVILISIVIFC 185
Query: 196 LSTMPDIRAEEERGECSPKCRS-------------LFVLETVCVAWFSFEFLLRSLQAES 242
L T+P+++ +++ + + F++ET+C+ WFSFE ++R S
Sbjct: 186 LETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFACPS 245
Query: 243 KCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGL-VLRLLRALRVLYVMRL 301
K F + +N IDI+A++P++++L +A G K + L +LR++R +RV + +L
Sbjct: 246 KTDFFKNIMNFIDIVAIIPYFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKL 305
Query: 302 ARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYW 361
+RHS GL+ LG T++ RE GLL+ FL + + LF+ V+ AE E A FSS+P ++W
Sbjct: 306 SRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAE-EAESHFSSIPDAFW 364
Query: 362 WAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQR 421
WAV+SMTTVGYGDM P ++ G++V ++G+L +A PV I F+ Y E +++
Sbjct: 365 WAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ 424
Query: 422 A-----ASPEPALQEDSTHSATATEDSSQ 445
A +SP A D + +++T S+
Sbjct: 425 AQLLHVSSPNLASDSDLSRRSSSTMSKSE 453
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 193 bits (491), Expect = 2e-49
Identities = 132/427 (30%), Positives = 214/427 (50%), Gaps = 57/427 (13%)
Query: 19 VIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAF 78
V+IN+ G R LA+ P L D + +D R+E+FFDR+ +F
Sbjct: 35 VVINISGLRFETQLKTLAQFPETLL---------GDPKKRMRYFDPLRNEYFFDRNRPSF 85
Query: 79 RAIVALLRAGKLRLLRGPCALA---FRDELAYWGIDEARLERCCLRRLRRREEEAAEARA 135
AI+ ++G LR P + F +E+ ++ + E +E + R +E +
Sbjct: 86 DAILYYYQSGGR--LRRPVNVPLDIFSEEIRFYELGEEAME------MFREDEGYIKEEE 137
Query: 136 GPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLC 195
P P QR ++ + + P S ++ A VSV + ++ V C
Sbjct: 138 RPL-------------PENEFQR---QVWLLFEYPESSGPARIIAIVSVMVILISIVSFC 181
Query: 196 LSTMPDIRAEEER------------------GECSPKCRSLFVLETVCVAWFSFEFLLRS 237
L T+P R E E + + F++ET+C+ WFSFEFL+R
Sbjct: 182 LETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRF 241
Query: 238 LQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAG--LVLRLLRALRV 295
SK F +NIIDI+A++P++++L LA P + ++A +LR++R +RV
Sbjct: 242 FACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVRV 301
Query: 296 LYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSS 355
+ +L+RHS GL+ LG T++ RE GLL+ FL + + LF+ V+ AE + F S
Sbjct: 302 FRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAD-ERESQFPS 360
Query: 356 VPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSEL 415
+P ++WWAV+SMTTVGYGDMVP ++ G++V ++G+L +A PV I F+ Y
Sbjct: 361 IPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRE 420
Query: 416 KEQQQRA 422
E +++A
Sbjct: 421 TEGEEQA 427
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 191 bits (485), Expect = 1e-48
Identities = 137/460 (29%), Positives = 228/460 (49%), Gaps = 68/460 (14%)
Query: 5 PCSPGGGGGTRARH------VIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRV 58
P GGGG + R+ V+INV G R LA+ P L D +
Sbjct: 158 PQDEGGGGYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLL---------GDPEKR 208
Query: 59 CDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAF---RDELAYWGIDEARL 115
+D R+E+FFDR+ +F AI+ ++G L+ P + F +E+ ++ + E L
Sbjct: 209 TQYFDPLRNEYFFDRNRPSFDAILYYYQSGGR--LKRPVNVPFDIFTEEVKFYQLGEEAL 266
Query: 116 ERCCLRRLRRREEEAAEARAGPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLA 175
L+ RE+E + RAL P ++++ + + P S
Sbjct: 267 -------LKFREDEGF----------VREEEDRAL-PENEF---KKQIWLLFEYPESSSP 305
Query: 176 GKLFACVSVSFVAVTAVGLCLSTMPDIRAEEE--------------RGECSPKCRS---- 217
+ A VSV + ++ V CL T+P+ R + + +P +
Sbjct: 306 ARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHT 365
Query: 218 -----LFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAA 272
F++ETVC+ WFSFEF++R S+ F + +NIIDI+++LP++++L LA
Sbjct: 366 IFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQ 425
Query: 273 GPGGTKLLERAGL---VLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFL 329
GG ++ + +LR++R +RV + +L+RHS GL+ LG T+R RE GLL+ FL
Sbjct: 426 QQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFL 485
Query: 330 CVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSS 389
+ + LF+ V+ AE + F S+P ++WWAV++MTTVGYGDM P ++ G++V
Sbjct: 486 FIGVILFSSAVYFAEAD-EPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLC 544
Query: 390 ILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPAL 429
++G+L +A PV I F+ Y E +++ + A+
Sbjct: 545 AIAGVLTIALPVPVIVSNFNYFYHRETENEEQTQLTQNAV 584
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,165,217
Number of Sequences: 37866
Number of extensions: 808216
Number of successful extensions: 4379
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 55
Number of HSP's that attempted gapping in prelim test: 3970
Number of HSP's gapped (non-prelim): 309
length of query: 466
length of database: 18,247,518
effective HSP length: 106
effective length of query: 360
effective length of database: 14,233,722
effective search space: 5124139920
effective search space used: 5124139920
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.