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Search of human proteins with 6912276
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912276 cysteine-rich hydrophobic domain 2 [Homo sapiens]
(165 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912276 cysteine-rich hydrophobic domain 2 [Homo sapiens] 351 1e-97
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 285 1e-77
gi|27735107 DnaJ (Hsp40) homolog, subfamily C, member 5 gamma [H... 34 0.050
gi|50541946 golgi autoantigen, golgin subfamily a, 7 [Homo sapiens] 33 0.15
gi|50541950 golgi autoantigen, golgin subfamily a, 7 [Homo sapiens] 33 0.15
gi|169204182 PREDICTED: hypothetical protein [Homo sapiens] 32 0.33
gi|4504191 mutS homolog 6 [Homo sapiens] 31 0.43
gi|55769589 transmembrane protein 63B [Homo sapiens] 31 0.43
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ... 31 0.56
gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform... 31 0.56
gi|32698730 nuclear fragile X mental retardation protein interac... 31 0.56
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 29 1.6
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 29 1.6
gi|169204828 PREDICTED: hypothetical protein [Homo sapiens] 29 1.6
gi|169205567 PREDICTED: hypothetical protein [Homo sapiens] 29 1.6
gi|82830428 gon-4-like isoform b [Homo sapiens] 29 1.6
gi|149158711 hypothetical protein LOC56673 [Homo sapiens] 29 1.6
gi|7662308 transmembrane protein 63A [Homo sapiens] 29 2.1
gi|145580615 KRI1 homolog [Homo sapiens] 28 2.8
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 28 3.6
gi|58219040 golgi autoantigen, golgin subfamily a, 7B [Homo sapi... 28 3.6
gi|29126218 DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Ho... 28 4.7
gi|56550065 complexin 2 [Homo sapiens] 27 6.2
gi|5729783 complexin 2 [Homo sapiens] 27 6.2
gi|42544241 iroquois homeobox protein 6 [Homo sapiens] 27 6.2
gi|21361405 regulator of G-protein signalling 17 [Homo sapiens] 27 8.0
gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens] 27 8.0
gi|53729363 leucine rich repeat and sterile alpha motif containi... 27 8.0
gi|53729361 leucine rich repeat and sterile alpha motif containi... 27 8.0
gi|53729359 leucine rich repeat and sterile alpha motif containi... 27 8.0
>gi|6912276 cysteine-rich hydrophobic domain 2 [Homo sapiens]
Length = 165
Score = 351 bits (901), Expect = 1e-97
Identities = 165/165 (100%), Positives = 165/165 (100%)
Query: 1 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVA 60
MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVA
Sbjct: 1 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVA 60
Query: 61 PEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLE 120
PEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLE
Sbjct: 61 PEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLE 120
Query: 121 WENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD 165
WENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
Sbjct: 121 WENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD 165
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 285 bits (729), Expect = 1e-77
Identities = 131/168 (77%), Positives = 149/168 (88%), Gaps = 7/168 (4%)
Query: 5 DEIYEEEEDEERA-------LEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTG 57
+E EEEE+EE A EE L +Y+PDPV+VRG+GH+TVFGLSNKF++EFPS LTG
Sbjct: 57 EEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTG 116
Query: 58 KVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEK 117
KVAPEEFK SI RVN+CLKK LPVNV+WLLCGCLCCCCTLGCS+WPVICL+KRTRRSI+K
Sbjct: 117 KVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQK 176
Query: 118 LLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD 165
L+EWENNRLYHKL LHW+L+KRKCET+NMMEYVILIEFLPK PIFRPD
Sbjct: 177 LIEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD 224
>gi|27735107 DnaJ (Hsp40) homolog, subfamily C, member 5 gamma [Homo
sapiens]
Length = 189
Score = 34.3 bits (77), Expect = 0.050
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 71 VNSCLKKNLPVNVRWLLCGCLCCCCTLGC 99
+NSC K L + L C C CCCC C
Sbjct: 119 LNSCWFKTLVILCTLLTCCCFCCCCCFCC 147
>gi|50541946 golgi autoantigen, golgin subfamily a, 7 [Homo sapiens]
Length = 137
Score = 32.7 bits (73), Expect = 0.15
Identities = 16/89 (17%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
Query: 42 GLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSM 101
G +F+++FP+ L ++ ++F+ ++ +N+ + + + L GCL C
Sbjct: 21 GTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTI-- 78
Query: 102 WPVICLS---KRTRRSIEKLLEWENNRLY 127
+C+ ++ + + K ++ +N ++Y
Sbjct: 79 --FLCMETHYEKVLKKVSKYIQEQNEKIY 105
>gi|50541950 golgi autoantigen, golgin subfamily a, 7 [Homo sapiens]
Length = 137
Score = 32.7 bits (73), Expect = 0.15
Identities = 16/89 (17%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
Query: 42 GLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSM 101
G +F+++FP+ L ++ ++F+ ++ +N+ + + + L GCL C
Sbjct: 21 GTRCQFQTKFPAELENRIDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTI-- 78
Query: 102 WPVICLS---KRTRRSIEKLLEWENNRLY 127
+C+ ++ + + K ++ +N ++Y
Sbjct: 79 --FLCMETHYEKVLKKVSKYIQEQNEKIY 105
>gi|169204182 PREDICTED: hypothetical protein [Homo sapiens]
Length = 220
Score = 31.6 bits (70), Expect = 0.33
Identities = 10/20 (50%), Positives = 10/20 (50%)
Query: 88 CGCLCCCCTLGCSMWPVICL 107
C C CCCC C W CL
Sbjct: 155 CCCCCCCCCCCCCCWCCSCL 174
>gi|4504191 mutS homolog 6 [Homo sapiens]
Length = 1360
Score = 31.2 bits (69), Expect = 0.43
Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 2 ADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLS-NKFESEFPSSLTGKVA 60
A FD Y++ + R E+ LL+Y G + +G+ N+++ E P + T +
Sbjct: 931 AGFDSDYDQALADIRENEQSLLEYLEKQRNRIGCRTIVYWGIGRNRYQLEIPENFTTRNL 990
Query: 61 PEEFK 65
PEE++
Sbjct: 991 PEEYE 995
>gi|55769589 transmembrane protein 63B [Homo sapiens]
Length = 832
Score = 31.2 bits (69), Expect = 0.43
Identities = 14/54 (25%), Positives = 25/54 (46%)
Query: 76 KKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHK 129
K+N+P + CG LCCC GC I + + +++ + E ++ K
Sbjct: 304 KENVPTMINPKPCGHLCCCVVRGCEQVEAIEYYTKLEQKLKEDYKREKEKVNEK 357
>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
[Homo sapiens]
Length = 621
Score = 30.8 bits (68), Expect = 0.56
Identities = 17/45 (37%), Positives = 23/45 (51%)
Query: 1 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSN 45
+ D E+ EE EDEE LEE + + DP + H V GL +
Sbjct: 53 LEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGH 97
>gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform
2 [Homo sapiens]
Length = 568
Score = 30.8 bits (68), Expect = 0.56
Identities = 17/45 (37%), Positives = 23/45 (51%)
Query: 1 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSN 45
+ D E+ EE EDEE LEE + + DP + H V GL +
Sbjct: 53 LEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGH 97
>gi|32698730 nuclear fragile X mental retardation protein
interacting protein 2 [Homo sapiens]
Length = 695
Score = 30.8 bits (68), Expect = 0.56
Identities = 17/72 (23%), Positives = 34/72 (47%)
Query: 8 YEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKAS 67
YE + E +++++ P+ VV SG++T + +++ S +G P++ KA
Sbjct: 168 YENKSGENQSVDKSDTIPIPNGVVTNNSGYITNGYMGKGADNDGSGSESGYTTPKKRKAR 227
Query: 68 INRVNSCLKKNL 79
N C N+
Sbjct: 228 RNSAKGCENLNI 239
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 29.3 bits (64), Expect = 1.6
Identities = 14/24 (58%), Positives = 18/24 (75%), Gaps = 3/24 (12%)
Query: 1 MADFDEI---YEEEEDEERALEEQ 21
M+D +E+ YEEEE EE A+EEQ
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEQ 24
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 29.3 bits (64), Expect = 1.6
Identities = 14/24 (58%), Positives = 18/24 (75%), Gaps = 3/24 (12%)
Query: 1 MADFDEI---YEEEEDEERALEEQ 21
M+D +E+ YEEEE EE A+EEQ
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEQ 24
>gi|169204828 PREDICTED: hypothetical protein [Homo sapiens]
Length = 219
Score = 29.3 bits (64), Expect = 1.6
Identities = 9/18 (50%), Positives = 9/18 (50%)
Query: 90 CLCCCCTLGCSMWPVICL 107
C CCCC C W CL
Sbjct: 156 CCCCCCCCCCCCWCCSCL 173
>gi|169205567 PREDICTED: hypothetical protein [Homo sapiens]
Length = 219
Score = 29.3 bits (64), Expect = 1.6
Identities = 9/18 (50%), Positives = 9/18 (50%)
Query: 90 CLCCCCTLGCSMWPVICL 107
C CCCC C W CL
Sbjct: 156 CCCCCCCCCCCCWCCSCL 173
>gi|82830428 gon-4-like isoform b [Homo sapiens]
Length = 1529
Score = 29.3 bits (64), Expect = 1.6
Identities = 15/45 (33%), Positives = 24/45 (53%)
Query: 3 DFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKF 47
DFD++ ++EEDE + E+ + P+ V G GLSN +
Sbjct: 1464 DFDDLTQDEEDEMSSASEESVLSVPELQVRAGEYSQVFRGLSNMY 1508
>gi|149158711 hypothetical protein LOC56673 [Homo sapiens]
Length = 467
Score = 29.3 bits (64), Expect = 1.6
Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 86 LLC-GCLCCCCTLGCSMWPVICLSKRTRRSIEKL 118
LLC GCLC C G + WP+ S+ R + +L
Sbjct: 276 LLCQGCLCGCPPCGTTWWPLTRTSEVMARELPEL 309
>gi|7662308 transmembrane protein 63A [Homo sapiens]
Length = 807
Score = 28.9 bits (63), Expect = 2.1
Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 88 CGCLCCCCTLGCSMWPVICLSKRTR-RSIEKLLEWENN 124
CG CCC LGC I R + R +E++ E E +
Sbjct: 304 CGQFCCCEVLGCEWEDAISYYTRMKDRLLERITEEERH 341
>gi|145580615 KRI1 homolog [Homo sapiens]
Length = 709
Score = 28.5 bits (62), Expect = 2.8
Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 8/75 (10%)
Query: 4 FDEIYEEEEDEERALEEQLLKYSPDPVVVRGS---GHVTV-----FGLSNKFESEFPSSL 55
++E EEEEDEE EE+ + P + V S G + + F F E P S
Sbjct: 255 YEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSA 314
Query: 56 TGKVAPEEFKASINR 70
+ K P +S+ R
Sbjct: 315 SVKTYPRSIASSVRR 329
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 28.1 bits (61), Expect = 3.6
Identities = 13/24 (54%), Positives = 18/24 (75%), Gaps = 3/24 (12%)
Query: 1 MADFDEI---YEEEEDEERALEEQ 21
M+D +E+ YEEEE EE A+EE+
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEE 24
>gi|58219040 golgi autoantigen, golgin subfamily a, 7B [Homo
sapiens]
Length = 167
Score = 28.1 bits (61), Expect = 3.6
Identities = 14/85 (16%), Positives = 41/85 (48%), Gaps = 7/85 (8%)
Query: 46 KFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVI 105
+F+++FP L ++ + F+ ++ +N + + L GCL C + + +
Sbjct: 34 QFQTKFPPELDSRIERQLFEETVKTLNGFYAEAEKIGGSSYLEGCLAC----ATAYFIFL 89
Query: 106 CLS---KRTRRSIEKLLEWENNRLY 127
C+ ++ + I + ++ +N +++
Sbjct: 90 CMETHYEKVLKKISRYIQEQNEKIF 114
>gi|29126218 DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Homo
sapiens]
Length = 199
Score = 27.7 bits (60), Expect = 4.7
Identities = 8/12 (66%), Positives = 8/12 (66%)
Query: 88 CGCLCCCCTLGC 99
C CLCCCC C
Sbjct: 126 CCCLCCCCNCCC 137
>gi|56550065 complexin 2 [Homo sapiens]
Length = 134
Score = 27.3 bits (59), Expect = 6.2
Identities = 10/22 (45%), Positives = 17/22 (77%)
Query: 9 EEEEDEERALEEQLLKYSPDPV 30
+EEE+EE ++ + +LKY P P+
Sbjct: 107 DEEEEEEESILDTVLKYLPGPL 128
>gi|5729783 complexin 2 [Homo sapiens]
Length = 134
Score = 27.3 bits (59), Expect = 6.2
Identities = 10/22 (45%), Positives = 17/22 (77%)
Query: 9 EEEEDEERALEEQLLKYSPDPV 30
+EEE+EE ++ + +LKY P P+
Sbjct: 107 DEEEEEEESILDTVLKYLPGPL 128
>gi|42544241 iroquois homeobox protein 6 [Homo sapiens]
Length = 446
Score = 27.3 bits (59), Expect = 6.2
Identities = 10/28 (35%), Positives = 21/28 (75%)
Query: 1 MADFDEIYEEEEDEERALEEQLLKYSPD 28
++D +++ EEEE+EE A +E+++ + D
Sbjct: 253 LSDLEDLEEEEEEEEEAEDEEVVATAGD 280
>gi|21361405 regulator of G-protein signalling 17 [Homo sapiens]
Length = 210
Score = 26.9 bits (58), Expect = 8.0
Identities = 7/12 (58%), Positives = 8/12 (66%)
Query: 88 CGCLCCCCTLGC 99
C C CCCC+ C
Sbjct: 29 CFCWCCCCSCSC 40
>gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens]
Length = 480
Score = 26.9 bits (58), Expect = 8.0
Identities = 8/16 (50%), Positives = 9/16 (56%)
Query: 80 PVNVRWLLCGCLCCCC 95
P+ W L C CCCC
Sbjct: 455 PLGCCWQLTRCCCCCC 470
>gi|53729363 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 26.9 bits (58), Expect = 8.0
Identities = 13/45 (28%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
Query: 50 EFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCC 94
E P S+ P E + + CL++ + +L CG +CCC
Sbjct: 654 EPPESVRPSAPPAELEVQASECVVCLERE--AQMIFLNCGHVCCC 696
>gi|53729361 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 26.9 bits (58), Expect = 8.0
Identities = 13/45 (28%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
Query: 50 EFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCC 94
E P S+ P E + + CL++ + +L CG +CCC
Sbjct: 654 EPPESVRPSAPPAELEVQASECVVCLERE--AQMIFLNCGHVCCC 696
>gi|53729359 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 26.9 bits (58), Expect = 8.0
Identities = 13/45 (28%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
Query: 50 EFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCC 94
E P S+ P E + + CL++ + +L CG +CCC
Sbjct: 654 EPPESVRPSAPPAELEVQASECVVCLERE--AQMIFLNCGHVCCC 696
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.448
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,140,475
Number of Sequences: 37866
Number of extensions: 321930
Number of successful extensions: 1726
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1640
Number of HSP's gapped (non-prelim): 63
length of query: 165
length of database: 18,247,518
effective HSP length: 94
effective length of query: 71
effective length of database: 14,688,114
effective search space: 1042856094
effective search space used: 1042856094
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.