BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|67551265 transcription factor ELYS [Homo sapiens] (2266 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|67551265 transcription factor ELYS [Homo sapiens] 4457 0.0 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 62 5e-09 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 62 5e-09 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 62 8e-09 gi|87299628 biorientation of chromosomes in cell division 1-like... 61 1e-08 gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 59 5e-08 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 56 5e-07 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 55 6e-07 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 52 5e-06 gi|153945728 microtubule-associated protein 1B [Homo sapiens] 52 5e-06 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 52 9e-06 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 50 2e-05 gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 50 3e-05 gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 50 3e-05 gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 50 3e-05 gi|110611184 chromodomain helicase DNA binding protein 2 isoform... 50 3e-05 gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 50 3e-05 gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 50 3e-05 gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 50 3e-05 gi|104526627 triadin [Homo sapiens] 50 3e-05 gi|117676384 splicing factor, arginine/serine-rich 2, interactin... 49 7e-05 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 48 1e-04 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 48 1e-04 gi|71061468 centromere protein E [Homo sapiens] 48 1e-04 gi|41322923 plectin 1 isoform 11 [Homo sapiens] 48 1e-04 gi|41322914 plectin 1 isoform 10 [Homo sapiens] 48 1e-04 gi|41322919 plectin 1 isoform 8 [Homo sapiens] 48 1e-04 gi|41322910 plectin 1 isoform 7 [Homo sapiens] 48 1e-04 gi|41322916 plectin 1 isoform 6 [Homo sapiens] 48 1e-04 gi|41322908 plectin 1 isoform 3 [Homo sapiens] 48 1e-04 >gi|67551265 transcription factor ELYS [Homo sapiens] Length = 2266 Score = 4457 bits (11559), Expect = 0.0 Identities = 2266/2266 (100%), Positives = 2266/2266 (100%) Query: 1 MRDLRAQVTSGLLPFPEVTLQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSI 60 MRDLRAQVTSGLLPFPEVTLQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSI Sbjct: 1 MRDLRAQVTSGLLPFPEVTLQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSI 60 Query: 61 TGERLSAYRFSGVNEQPPVVLAVKEFSWQKRTGLLIGLEETEGSVLCLYDLGISKVVKAV 120 TGERLSAYRFSGVNEQPPVVLAVKEFSWQKRTGLLIGLEETEGSVLCLYDLGISKVVKAV Sbjct: 61 TGERLSAYRFSGVNEQPPVVLAVKEFSWQKRTGLLIGLEETEGSVLCLYDLGISKVVKAV 120 Query: 121 VLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLVDLCLDDLSCNQN 180 VLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLVDLCLDDLSCNQN Sbjct: 121 VLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLVDLCLDDLSCNQN 180 Query: 181 EVEASDLEVLTGIPAEVPHIRESVMRQGRHLCFQLVSPTGTAVSTLSYISRTNQLAVGFS 240 EVEASDLEVLTGIPAEVPHIRESVMRQGRHLCFQLVSPTGTAVSTLSYISRTNQLAVGFS Sbjct: 181 EVEASDLEVLTGIPAEVPHIRESVMRQGRHLCFQLVSPTGTAVSTLSYISRTNQLAVGFS 240 Query: 241 DGYLALWNMKSMKREYYIQLESGQVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLS 300 DGYLALWNMKSMKREYYIQLESGQVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLS Sbjct: 241 DGYLALWNMKSMKREYYIQLESGQVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLS 300 Query: 301 LHLLQLAFGNRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTSNTKLLGCQSIEKF 360 LHLLQLAFGNRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTSNTKLLGCQSIEKF Sbjct: 301 LHLLQLAFGNRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTSNTKLLGCQSIEKF 360 Query: 361 RSHGDREEGVNEALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGE 420 RSHGDREEGVNEALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGE Sbjct: 361 RSHGDREEGVNEALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGE 420 Query: 421 YLHNCSYFALWSLESVVSRTSPHGILDILVHERSLNRGVPPSYPPPEQFFNPSTYNFDAT 480 YLHNCSYFALWSLESVVSRTSPHGILDILVHERSLNRGVPPSYPPPEQFFNPSTYNFDAT Sbjct: 421 YLHNCSYFALWSLESVVSRTSPHGILDILVHERSLNRGVPPSYPPPEQFFNPSTYNFDAT 480 Query: 481 CLLNSGVVHLTCTGFQKETLTFLKKSGPSLNELIPDGYNRCLVAGLLSPRFVDVQPSSLS 540 CLLNSGVVHLTCTGFQKETLTFLKKSGPSLNELIPDGYNRCLVAGLLSPRFVDVQPSSLS Sbjct: 481 CLLNSGVVHLTCTGFQKETLTFLKKSGPSLNELIPDGYNRCLVAGLLSPRFVDVQPSSLS 540 Query: 541 QEEQLEAILSAAIQTSSLGLLTGYIRRWITEEQPNSATNLRFVLEWTWNKVVLTKEEFDR 600 QEEQLEAILSAAIQTSSLGLLTGYIRRWITEEQPNSATNLRFVLEWTWNKVVLTKEEFDR Sbjct: 541 QEEQLEAILSAAIQTSSLGLLTGYIRRWITEEQPNSATNLRFVLEWTWNKVVLTKEEFDR 600 Query: 601 LCVPLFDGSCHFMDPQTIQSIQQCYLLLSNLNIVLSCFASEAREITERGLIDLSNKFVVS 660 LCVPLFDGSCHFMDPQTIQSIQQCYLLLSNLNIVLSCFASEAREITERGLIDLSNKFVVS Sbjct: 601 LCVPLFDGSCHFMDPQTIQSIQQCYLLLSNLNIVLSCFASEAREITERGLIDLSNKFVVS 660 Query: 661 HLICQYAQVVLWFSHSGLLPEGIDDSVQLSRLCYNYPVIQNYYTSRRQKFERLSRGKWNP 720 HLICQYAQVVLWFSHSGLLPEGIDDSVQLSRLCYNYPVIQNYYTSRRQKFERLSRGKWNP Sbjct: 661 HLICQYAQVVLWFSHSGLLPEGIDDSVQLSRLCYNYPVIQNYYTSRRQKFERLSRGKWNP 720 Query: 721 DCLMIDGLVSQLGERIEKLWKRDEGGTGKYPPASLHAVLDMYLLDGVTEAAKHSITIYLL 780 DCLMIDGLVSQLGERIEKLWKRDEGGTGKYPPASLHAVLDMYLLDGVTEAAKHSITIYLL Sbjct: 721 DCLMIDGLVSQLGERIEKLWKRDEGGTGKYPPASLHAVLDMYLLDGVTEAAKHSITIYLL 780 Query: 781 LDIMYSFPNKTDTPIESFPTVFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPLS 840 LDIMYSFPNKTDTPIESFPTVFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPLS Sbjct: 781 LDIMYSFPNKTDTPIESFPTVFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPLS 840 Query: 841 WQHSKIIQAFMSQGEHRQALRYIQTMKPTVSSGNDVILHLTVLLFNRCMVEAWNFLRQHC 900 WQHSKIIQAFMSQGEHRQALRYIQTMKPTVSSGNDVILHLTVLLFNRCMVEAWNFLRQHC Sbjct: 841 WQHSKIIQAFMSQGEHRQALRYIQTMKPTVSSGNDVILHLTVLLFNRCMVEAWNFLRQHC 900 Query: 901 NRLNIEELLKHMYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQ 960 NRLNIEELLKHMYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQ Sbjct: 901 NRLNIEELLKHMYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQ 960 Query: 961 RANYVPALKLNQTLKINVMNDRDPRLRERSLARNSILDQYGKILPRVHRKLAIERAKPYH 1020 RANYVPALKLNQTLKINVMNDRDPRLRERSLARNSILDQYGKILPRVHRKLAIERAKPYH Sbjct: 961 RANYVPALKLNQTLKINVMNDRDPRLRERSLARNSILDQYGKILPRVHRKLAIERAKPYH 1020 Query: 1021 LSTSSVFRLVSRPKPLSAVPKQVVTGTVLTRSVFINNVLSKIGEVWASKEPINSTTPFNS 1080 LSTSSVFRLVSRPKPLSAVPKQVVTGTVLTRSVFINNVLSKIGEVWASKEPINSTTPFNS Sbjct: 1021 LSTSSVFRLVSRPKPLSAVPKQVVTGTVLTRSVFINNVLSKIGEVWASKEPINSTTPFNS 1080 Query: 1081 SKIEEPSPIVYSLPAPELPEAFFGTPISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSM 1140 SKIEEPSPIVYSLPAPELPEAFFGTPISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSM Sbjct: 1081 SKIEEPSPIVYSLPAPELPEAFFGTPISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSM 1140 Query: 1141 KSPLYLVSRSLPSSSQLKGSPQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQ 1200 KSPLYLVSRSLPSSSQLKGSPQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQ Sbjct: 1141 KSPLYLVSRSLPSSSQLKGSPQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQ 1200 Query: 1201 SILRSTLRSTPLASPSPSPGRSPQRLKETRISFVEEDVHPKWIPGAADDSKLEVFTTPKK 1260 SILRSTLRSTPLASPSPSPGRSPQRLKETRISFVEEDVHPKWIPGAADDSKLEVFTTPKK Sbjct: 1201 SILRSTLRSTPLASPSPSPGRSPQRLKETRISFVEEDVHPKWIPGAADDSKLEVFTTPKK 1260 Query: 1261 CAVPVETEWLKSKDRTTSFFLNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLE 1320 CAVPVETEWLKSKDRTTSFFLNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLE Sbjct: 1261 CAVPVETEWLKSKDRTTSFFLNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLE 1320 Query: 1321 YQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNL 1380 YQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNL Sbjct: 1321 YQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNL 1380 Query: 1381 EDAETKDLLVAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVET 1440 EDAETKDLLVAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVET Sbjct: 1381 EDAETKDLLVAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVET 1440 Query: 1441 YTPAIRANDNKSMADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKES 1500 YTPAIRANDNKSMADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKES Sbjct: 1441 YTPAIRANDNKSMADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKES 1500 Query: 1501 VDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTI 1560 VDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTI Sbjct: 1501 VDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTI 1560 Query: 1561 DQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANT 1620 DQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANT Sbjct: 1561 DQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANT 1620 Query: 1621 ATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTR 1680 ATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTR Sbjct: 1621 ATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTR 1680 Query: 1681 SKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTR 1740 SKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTR Sbjct: 1681 SKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTR 1740 Query: 1741 TRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQ 1800 TRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQ Sbjct: 1741 TRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQ 1800 Query: 1801 QIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKK 1860 QIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKK Sbjct: 1801 QIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKK 1860 Query: 1861 EVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNK 1920 EVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNK Sbjct: 1861 EVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNK 1920 Query: 1921 QDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKI 1980 QDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKI Sbjct: 1921 QDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKI 1980 Query: 1981 NPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSM 2040 NPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSM Sbjct: 1981 NPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSM 2040 Query: 2041 VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR 2100 VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR Sbjct: 2041 VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR 2100 Query: 2101 SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS 2160 SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS Sbjct: 2101 SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS 2160 Query: 2161 RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRL 2220 RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRL Sbjct: 2161 RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRL 2220 Query: 2221 ISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRKML 2266 ISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRKML Sbjct: 2221 ISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRKML 2266 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 62.4 bits (150), Expect = 5e-09 Identities = 196/1053 (18%), Positives = 383/1053 (36%), Gaps = 189/1053 (17%) Query: 1286 KEHQEMD----------EGSQSLEKLDVSKGNSSVSITSDETTLEYQDAPSPEDLEETVF 1335 KEH+ +D E +LEK D+SK + +S ++ +Q+ P+ E Sbjct: 392 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST 451 Query: 1336 TASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNLEDAETKDLLVAAEAF 1395 KS T +D D D+ + PS + + + E+ ET A E Sbjct: 452 GGEHKKSDRKEEPQYEPANTSEDLDMDIVS---VPSSVPEDI--FENLET-----AMEVQ 501 Query: 1396 SELNHLSP-VQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSV--ETY---TPAIRAND 1449 S ++H GTE + + SV + I ++ ++ + + V E Y TP +N Sbjct: 502 SSVDHQGDGSSGTEQEVESSSV-KLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNS 560 Query: 1450 NKSMADV--LGDGGNSSLTISEGPIVSERRLNQEVALNLKEDH--EVEVGVLKESVDL-- 1503 AD + + + P + + L QE N +H E EV +L E DL Sbjct: 561 PIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQE---NSDNEHLVENEVSLLLEESDLRR 617 Query: 1504 -----------PEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLK 1552 P E P++ + + V E++KL ++ RN S + + K Sbjct: 618 SPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNK 677 Query: 1553 L--QYNFDTIDQ-----------QFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGE 1599 L +T+DQ + + +++ DI E+ T + + Sbjct: 678 LPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDD 737 Query: 1600 EGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPY 1659 +G+ + S + + ++ + + +N S + + KS Sbjct: 738 KGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMS------ 791 Query: 1660 VPEPIKVAIAENLLDVIKDTRSKEITSDT------MEQSIHETIPLVSQNIM--CPTKLV 1711 K+ A I +T+ + + D M+ H+ + + K Sbjct: 792 -----KIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE 846 Query: 1712 KSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKM---P 1768 + F +A+ T + ++ D + K + V+ S ++++ + K+ Sbjct: 847 RETFSSAEGTVDKDTTIMELRDRLPKKQQASAS-TDGVDKLSGKEQSFTSLEVRKVAETK 905 Query: 1769 GQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQ-NSVTPRRGRRKKEVNQDILENTS 1827 +S KT+ K++ + +I Q+ + + + ++G +K+ D + Sbjct: 906 EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVI 965 Query: 1828 SVEQELQITTGRESKRLKSSQL------LEPAVEETTKKEVKVSSVTKRTPRR------- 1874 +EQ+ + ++ K + ++ ++ TT E K + +T ++ Sbjct: 966 KMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDY 1025 Query: 1875 IKRSVENQESVEIINDLK-----VSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQ 1929 ++S +S + D K +++ K D S + K K Sbjct: 1026 AEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCN 1085 Query: 1930 LRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSK 1989 K ++R+ ++RE NL S + T + + S+ + SED Sbjct: 1086 SSDKRLKRI--------ELRERRNLSSKRNTKEIQSGSSSSDAEES-------SED---N 1127 Query: 1990 AVKEERSPKKKEAPSI--RRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKK 2047 K++R+ KK+A + ++R++ T K + D+ Sbjct: 1128 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI------------------------- 1162 Query: 2048 LTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILL 2107 T + S + +S+ E +DE K E L + F +SS S + + Sbjct: 1163 -TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLV-LSSHTGFCQSSGDEALSKSVPVTV 1220 Query: 2108 PDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSN 2167 D + N+ P AKK+ L+E+ ++LSS + +S+ Sbjct: 1221 DDDDDDND----------PENRIAKKM----LLEEIKANLSSD-----------EDGSSD 1255 Query: 2168 KNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLASP 2227 E + + Q+ E G +AK S++ S+ ++K P RL+ + Sbjct: 1256 DEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK------PRYRHRLLRHKLTV 1309 Query: 2228 ADG-----VKSKPRKTTEVTGTGLGRNRKKLSS 2255 +DG K+KP++ EV GRNR+K+SS Sbjct: 1310 SDGESGEEKKTKPKEHKEVK----GRNRRKVSS 1338 Score = 45.8 bits (107), Expect = 5e-04 Identities = 75/366 (20%), Positives = 137/366 (37%), Gaps = 62/366 (16%) Query: 1774 KKTRKAKEISEASENIYSDVRG--LSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQ 1831 K +RK ++ S + YS S ++++ + + RR K ++I +SS + Sbjct: 1061 KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDA 1120 Query: 1832 ELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDL 1891 E ++ K+ SS+ V+E + ++ S TKR I S + +E + Sbjct: 1121 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTS--TKRKQADITSS--SSSDIEDDDQN 1176 Query: 1892 KVSTVTSPSRMIRKLRSTNLDASENTGNKQ-----------------DDKSSDKQLRIKH 1934 + +S + I+ + + NL S +TG Q DD +D + RI Sbjct: 1177 SIGEGSSDEQKIKPV-TENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1235 Query: 1935 ---VRRVRGREVSPSDVREDSNLES-------------------SQLTVQAEFDMSAIPR 1972 + ++ S D D E +Q+ +++ D + Sbjct: 1236 KMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1295 Query: 1973 KRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAK-SENVDVGKPALGKSI 2031 R R R + V EE+ K KE ++ R+ R ++ SE+ D + + + + Sbjct: 1296 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1355 Query: 2032 LVPNEELSMVMSSKKK--LTKKTESQSQKRSLHSV-------------SEERTDEMTHKE 2076 +E S KK L + S QK+ + SEE +E +E Sbjct: 1356 SESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE 1415 Query: 2077 TNEQEE 2082 E+EE Sbjct: 1416 EEEEEE 1421 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 62.4 bits (150), Expect = 5e-09 Identities = 196/1053 (18%), Positives = 383/1053 (36%), Gaps = 189/1053 (17%) Query: 1286 KEHQEMD----------EGSQSLEKLDVSKGNSSVSITSDETTLEYQDAPSPEDLEETVF 1335 KEH+ +D E +LEK D+SK + +S ++ +Q+ P+ E Sbjct: 430 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST 489 Query: 1336 TASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNLEDAETKDLLVAAEAF 1395 KS T +D D D+ + PS + + + E+ ET A E Sbjct: 490 GGEHKKSDRKEEPQYEPANTSEDLDMDIVS---VPSSVPEDI--FENLET-----AMEVQ 539 Query: 1396 SELNHLSP-VQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSV--ETY---TPAIRAND 1449 S ++H GTE + + SV + I ++ ++ + + V E Y TP +N Sbjct: 540 SSVDHQGDGSSGTEQEVESSSV-KLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNS 598 Query: 1450 NKSMADV--LGDGGNSSLTISEGPIVSERRLNQEVALNLKEDH--EVEVGVLKESVDL-- 1503 AD + + + P + + L QE N +H E EV +L E DL Sbjct: 599 PIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQE---NSDNEHLVENEVSLLLEESDLRR 655 Query: 1504 -----------PEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLK 1552 P E P++ + + V E++KL ++ RN S + + K Sbjct: 656 SPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNK 715 Query: 1553 L--QYNFDTIDQ-----------QFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGE 1599 L +T+DQ + + +++ DI E+ T + + Sbjct: 716 LPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDD 775 Query: 1600 EGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPY 1659 +G+ + S + + ++ + + +N S + + KS Sbjct: 776 KGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMS------ 829 Query: 1660 VPEPIKVAIAENLLDVIKDTRSKEITSDT------MEQSIHETIPLVSQNIM--CPTKLV 1711 K+ A I +T+ + + D M+ H+ + + K Sbjct: 830 -----KIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE 884 Query: 1712 KSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKM---P 1768 + F +A+ T + ++ D + K + V+ S ++++ + K+ Sbjct: 885 RETFSSAEGTVDKDTTIMELRDRLPKKQQASAS-TDGVDKLSGKEQSFTSLEVRKVAETK 943 Query: 1769 GQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQ-NSVTPRRGRRKKEVNQDILENTS 1827 +S KT+ K++ + +I Q+ + + + ++G +K+ D + Sbjct: 944 EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVI 1003 Query: 1828 SVEQELQITTGRESKRLKSSQL------LEPAVEETTKKEVKVSSVTKRTPRR------- 1874 +EQ+ + ++ K + ++ ++ TT E K + +T ++ Sbjct: 1004 KMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDY 1063 Query: 1875 IKRSVENQESVEIINDLK-----VSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQ 1929 ++S +S + D K +++ K D S + K K Sbjct: 1064 AEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCN 1123 Query: 1930 LRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSK 1989 K ++R+ ++RE NL S + T + + S+ + SED Sbjct: 1124 SSDKRLKRI--------ELRERRNLSSKRNTKEIQSGSSSSDAEES-------SED---N 1165 Query: 1990 AVKEERSPKKKEAPSI--RRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKK 2047 K++R+ KK+A + ++R++ T K + D+ Sbjct: 1166 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI------------------------- 1200 Query: 2048 LTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILL 2107 T + S + +S+ E +DE K E L + F +SS S + + Sbjct: 1201 -TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLV-LSSHTGFCQSSGDEALSKSVPVTV 1258 Query: 2108 PDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSN 2167 D + N+ P AKK+ L+E+ ++LSS + +S+ Sbjct: 1259 DDDDDDND----------PENRIAKKM----LLEEIKANLSSD-----------EDGSSD 1293 Query: 2168 KNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLASP 2227 E + + Q+ E G +AK S++ S+ ++K P RL+ + Sbjct: 1294 DEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK------PRYRHRLLRHKLTV 1347 Query: 2228 ADG-----VKSKPRKTTEVTGTGLGRNRKKLSS 2255 +DG K+KP++ EV GRNR+K+SS Sbjct: 1348 SDGESGEEKKTKPKEHKEVK----GRNRRKVSS 1376 Score = 45.8 bits (107), Expect = 5e-04 Identities = 75/366 (20%), Positives = 137/366 (37%), Gaps = 62/366 (16%) Query: 1774 KKTRKAKEISEASENIYSDVRG--LSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQ 1831 K +RK ++ S + YS S ++++ + + RR K ++I +SS + Sbjct: 1099 KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDA 1158 Query: 1832 ELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDL 1891 E ++ K+ SS+ V+E + ++ S TKR I S + +E + Sbjct: 1159 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTS--TKRKQADITSS--SSSDIEDDDQN 1214 Query: 1892 KVSTVTSPSRMIRKLRSTNLDASENTGNKQ-----------------DDKSSDKQLRIKH 1934 + +S + I+ + + NL S +TG Q DD +D + RI Sbjct: 1215 SIGEGSSDEQKIKPV-TENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1273 Query: 1935 ---VRRVRGREVSPSDVREDSNLES-------------------SQLTVQAEFDMSAIPR 1972 + ++ S D D E +Q+ +++ D + Sbjct: 1274 KMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1333 Query: 1973 KRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAK-SENVDVGKPALGKSI 2031 R R R + V EE+ K KE ++ R+ R ++ SE+ D + + + + Sbjct: 1334 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1393 Query: 2032 LVPNEELSMVMSSKKK--LTKKTESQSQKRSLHSV-------------SEERTDEMTHKE 2076 +E S KK L + S QK+ + SEE +E +E Sbjct: 1394 SESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE 1453 Query: 2077 TNEQEE 2082 E+EE Sbjct: 1454 EEEEEE 1459 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 61.6 bits (148), Expect = 8e-09 Identities = 99/462 (21%), Positives = 175/462 (37%), Gaps = 45/462 (9%) Query: 1765 PKMPGQSVRKKTRKAKEIS--EASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDI 1822 PK+P S K + ++I E SE V ++ Q+ + K+E ++ Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486 Query: 1823 L-----------ENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRT 1871 E T S E + +E+K + PA ++ +KE S ++ Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546 Query: 1872 PRRIKRSV-ENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDK-Q 1929 P + K E +S + SP+ ++ A E + + KS +K + Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE-VKSPEKAKSPAKEEAKSPAEAKSPEKAK 605 Query: 1930 LRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSK 1989 +K + SP V+E++ +S E S + P K E +K Sbjct: 606 SPVKEEAKSPAEAKSP--VKEEA--KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAK 661 Query: 1990 AVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLT 2049 + ++ +SP K EA S + + P K+E P KS + EE K K Sbjct: 662 SPEKAKSPVKAEAKSPEKAKS---PVKAE---AKSPEKAKSPV--KEEAKS--PEKAKSP 711 Query: 2050 KKTESQSQKRSLHSVSEE-RTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLP 2108 K E++S +++ V EE +T E E+ + + KS ++T K+ P Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK----SPEKAKSPEKAKTLDVKS---P 764 Query: 2109 DLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNK 2168 + P E SPA + P KAK+ E ++ S L ++ +K K Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED-------AKAPEKEIPKK 817 Query: 2169 NKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESA 2210 +++ +K++ + E K K+ K K EK+ + Sbjct: 818 EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDS 859 Score = 45.8 bits (107), Expect = 5e-04 Identities = 108/588 (18%), Positives = 203/588 (34%), Gaps = 73/588 (12%) Query: 1598 GEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTL 1657 GEE E E G+ + P A A+ EK S + A P+ S +K + Sbjct: 489 GEEEEAEGGEEETKS--PPAEEAASPEKEAKSPVKEE----AKSPAEAKSPEKEE----- 537 Query: 1658 PYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKL---VKSA 1714 P +V E K +E S +S + + P K K Sbjct: 538 --AKSPAEVKSPEKA----KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 591 Query: 1715 FKTAQETSTMTMNVSQVDDVVSS----KTRTRGQRIQNVNVKSAQQEASADVATPKMPGQ 1770 K+ E + S V + S K+ + + VKS ++ S K P + Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK 651 Query: 1771 SVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVE 1830 + + +AK +A + ++ + P+ + +P + K S V+ Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKS-------PEKAKSPVKAEAKSPEKAK-----SPVK 699 Query: 1831 QELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVT-KRTPRRIKRSVENQESVEIIN 1889 +E + ++ KS E E K VK + T ++ +K ++ E + Sbjct: 700 EE-----AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754 Query: 1890 DLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVR 1949 K V SP A E + D + +K V+ E + S ++ Sbjct: 755 KAKTLDVKSPE--------AKTPAKEEARSPADKFPEKAKSPVKE--EVKSPEKAKSPLK 804 Query: 1950 EDSNLESSQLTVQAEFDMSAIPRKRGR-------PRKINPSEDVGSKAVKEERSPKKKEA 2002 ED+ ++ + E ++ + P+K + + +E++ KK+EA Sbjct: 805 EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA 864 Query: 2003 PSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTE--SQSQKRS 2060 P + K V+ K + ++ E+ V + +K+ K E ++ + Sbjct: 865 PKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE 924 Query: 2061 LHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFS 2120 V+++ D+ KE ++ E+ A + T+ KA +P +P Sbjct: 925 KTEVAKKEPDDAKAKEPSKPAEKKEA------APEKKDTKEEKA------KKPEEKPKTE 972 Query: 2121 PASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNK 2168 ++ K +K+ P K S + Q PP + K K Sbjct: 973 AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020 Score = 38.5 bits (88), Expect = 0.076 Identities = 44/191 (23%), Positives = 76/191 (39%), Gaps = 20/191 (10%) Query: 2057 QKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNE 2116 +K + V EE K ++E + A + ++S +K+ P+ P E Sbjct: 513 EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP--PEAKSPEKE 570 Query: 2117 PLFSPAS-EVPRKAKA---KKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLE 2172 SPA + P KAK+ ++ + PA+ K S P + K+ ++ Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAK-------SPEKAKSPVKEEAKSPAEAKSPVK 623 Query: 2173 DELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWS------PPPIEIRLISPLAS 2226 +E K A+ V++ K K+ +K+ + +K+ EKE A S P E + S Sbjct: 624 EEAKSPAE-VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682 Query: 2227 PADGVKSKPRK 2237 P P K Sbjct: 683 PVKAEAKSPEK 693 Score = 33.1 bits (74), Expect = 3.2 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 2/80 (2%) Query: 2154 SPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSP 2213 SPPA + K+ +++E K A++ ++ K +AK K+ + +K+ KE A SP Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEA-KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 561 Query: 2214 PPIEIRLISPLASPADGVKS 2233 P + SPA+ VKS Sbjct: 562 PEAKSPEKEEAKSPAE-VKS 580 >gi|87299628 biorientation of chromosomes in cell division 1-like [Homo sapiens] Length = 3051 Score = 60.8 bits (146), Expect = 1e-08 Identities = 127/613 (20%), Positives = 232/613 (37%), Gaps = 99/613 (16%) Query: 1677 KDTRSKEITSDTMEQSI-----------HETIPLVSQNIMCPTKLVKSAFKTAQETSTMT 1725 +DT + +TSD+ME+ ++T S + TK V+ A+ + + Sbjct: 421 EDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAY--VHKPYLYS 478 Query: 1726 MNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEA 1785 S DD ++ + QR Q++ + ++ + K+ ++ RK K Sbjct: 479 KYYSDSDDELTVE-----QRRQSIAKEKEERLLRRQINREKL------EEKRKQKAEKTK 527 Query: 1786 SENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLK 1845 S R ++ S+ P+ R K ++L+ +E+++ ++ KR K Sbjct: 528 SSKTKGQGRSSVDLEESSTKSLEPKAARIK-----EVLKERKVLEKKVALS----KKRKK 578 Query: 1846 SSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLK-VSTVTSPSRMIR 1904 S+ VEE +KK+ + +K T + + +E + +LK V + PS+ R Sbjct: 579 DSR----NVEENSKKKQQYEEDSKETLKTSEHC--EKEKISSSKELKHVHAKSEPSKPAR 632 Query: 1905 KLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAE 1964 +L SE+ + D+ ++ +L +H RR V V+E+++ + V+ Sbjct: 633 RL-------SESL-HVVDENKNESKLEREHKRRT-STPVIMEGVQEETDTRDVKRQVERS 683 Query: 1965 FDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK 2024 + P+K+ K +S KKE S + + R + + V Sbjct: 684 EICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKH 743 Query: 2025 PALGKSILVPNEELSMVMSSKK-KLTKKTESQSQKRSLHS-------------------- 2063 G + +E + S K K+ + + QSQ+ L S Sbjct: 744 KYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLG 803 Query: 2064 -----VSEE--RTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNE 2116 VSE +TDE KE N++E RL +A TK+ SR S I L + Sbjct: 804 KDGKPVSEYIIKTDENVRKENNKKERRL--SAEKTKAEHKSRRSSDSKIQKDSLGSKQHG 861 Query: 2117 PLFSPASEVPRKAKA-----------KKIEVPAQLKELVSDLSSQFVISPPALRSRQKNT 2165 SE + K K EV + K L + ++ L+S+ K Sbjct: 862 ITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLV----LKSKSKTQ 917 Query: 2166 SNKNK-LEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPL 2224 + K +E EL++ A T KP ++ T++ +++S P E + P+ Sbjct: 918 GKQVKVVETELQEGATKQATTPKPDKEK----NTEENDSEKQRKSKVEDKPFEETGVEPV 973 Query: 2225 ASPADGVKSKPRK 2237 A +K Sbjct: 974 LETASSSAHSTQK 986 Score = 54.7 bits (130), Expect = 1e-06 Identities = 100/455 (21%), Positives = 185/455 (40%), Gaps = 83/455 (18%) Query: 1818 VNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKE---VKVSSVTKRTPRR 1874 +NQ+ +S E T+ R SK+L S +P + +T KE ++ K T Sbjct: 211 LNQEASAARASTETSNAKTSERASKKLPS----QPTTDTSTDKERTSEDMADKEKSTADS 266 Query: 1875 IKRSVENQESVEIINDLK--VSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRI 1932 +E E +DL V + + ++ L N D + + ++Q +KS+DK Sbjct: 267 GGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQES-SEQKNKSTDK---- 321 Query: 1933 KHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVK 1992 G + S+ + + E + T + +FD S SED ++ VK Sbjct: 322 -------GEKKPDSNEKGERKKEKKEKT-EKKFDHS------------KKSED--TQKVK 359 Query: 1993 EERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKT 2052 +E+ K+KE S++ S +N+ K++ V+ K E+ S++ S LT T Sbjct: 360 DEKQAKEKEVESLKLPSEKNS-NKAKTVEGTK-----------EDFSLIDSDVDGLTDIT 407 Query: 2053 ESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSE 2112 S L S E+ +E+ ++ E+ E T+ + ++ ++T++ + D SE Sbjct: 408 VSSVHTSDLSSFEEDTEEEVVTSDSMEEGE---ITSDDEEKNKQNKTKTQTS----DSSE 460 Query: 2113 PNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLE 2172 + + + P + SD + + + RQ K + Sbjct: 461 GKT-----------KSVRHAYVHKPYLYSKYYSDSDDELTVE----QRRQSIAKEKEERL 505 Query: 2173 DELKDDAQSVETLGKPKAKRIRTSKTK---QASKNTEKESAWSPPPIEIRLISPLASPAD 2229 + + + +E K KA++ ++SKTK ++S + E+ S S P R+ L Sbjct: 506 LRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVL----- 560 Query: 2230 GVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRK 2264 K RK E L + RKK S ++ ++K Sbjct: 561 ----KERKVLE-KKVALSKKRKKDSRNVEENSKKK 590 Score = 41.2 bits (95), Expect = 0.012 Identities = 128/631 (20%), Positives = 233/631 (36%), Gaps = 85/631 (13%) Query: 1281 LNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLEYQDAPSPEDL---EETVFTA 1337 LNS +KE + + G+ G SS + S LE +A SP L E+T Sbjct: 2466 LNSLQKEDKSPETGTA---------GGSSTASYSAGRGLE-GNANSPAHLRGPEQTSGQT 2515 Query: 1338 SKPKSSSTALTTNVTEQTEKDGDKDVFASEVT-----PSDLQKQMGNLEDAETKDLLVAA 1392 +K S S V K D V P++ Q NL+ + TK + Sbjct: 2516 AKDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHSFLPAEQQGSEDNLKTSTTKCITGQE 2575 Query: 1393 EAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVETYTPAIRANDNKS 1452 + + + P +L AP + D+ A + D+ S Sbjct: 2576 SKIAPSHTMIPPATYSVALLAPKCEQDLTIKNDYSGKWTDQA--------SAEKTGDDNS 2627 Query: 1453 MADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKES-VDLPEEKLPIS 1511 + G+ +T+S V + N+E LN+ +++ + E+ V EEK Sbjct: 2628 TRKSFPEEGDIMVTVSSEENVCDIG-NEESPLNVLGGLKLKANLKMEAYVPSEEEKNGEI 2686 Query: 1512 DSPPDT------------QEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDT 1559 +PP++ Q ++ E L ++SG +E Y G + D Sbjct: 2687 LAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSESYNKGEISSGRK-DN 2745 Query: 1560 IDQQFCDLADNKDTAECDIAEVDGEL--FVAQSNFTLILEGEEGEVEPGDFASSDVLPKA 1617 + A + + E D EV+ E + L E+ EP D + DVL Sbjct: 2746 AE------AISGHSVEADPKEVEEEERHMPKRKRKQHYLSSED---EPDD--NPDVLDSR 2794 Query: 1618 ANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIK 1677 TA + E + H T ++ S+ ++ LP + +++ Sbjct: 2795 IETAQRQ----CPETEPHD---------TKEENSRDLEELPKTSSETN-STTSRVMEEKD 2840 Query: 1678 DTRSKEITSDTMEQSIHETIP--------LVSQNIMCPTKL-VKSAFKTAQETSTMTMNV 1728 + S E T + EQ+ +TI ++ + P K V++ K ++ T T V Sbjct: 2841 EYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIV 2900 Query: 1729 SQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASEN 1788 + SSK + N + Q+ + ++ + SVR++ RK K S++ Sbjct: 2901 TVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDD 2960 Query: 1789 IYSDVRGLSQNQQIPQNSVT-PRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSS 1847 S S+ ++ Q SV+ P ++++E +++ E + S+ +S Sbjct: 2961 AES-----SEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRSK 3015 Query: 1848 QLLEPAVEETTKKEVKVSSVTKRTPRRIKRS 1878 L P+++ K+EV R +R++ + Sbjct: 3016 TQLSPSIKR--KREVSPPGARTRGQQRVEEA 3044 Score = 38.5 bits (88), Expect = 0.076 Identities = 52/230 (22%), Positives = 90/230 (39%), Gaps = 41/230 (17%) Query: 1900 SRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQL 1959 SR + +L T+ + + T ++K E S S+ + ++ Sbjct: 2815 SRDLEELPKTSSETNSTTSRVMEEKD----------------EYSSSETTGEKPEQNDDD 2858 Query: 1960 TV--QAEFDMSAIPRKRGRPRKI----------NPSEDVGSKAVKEERSPKKKEAPSI-- 2005 T+ Q E I RKRGRPRK + D G V++ S K + Sbjct: 2859 TIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDE 2918 Query: 2006 RRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQS---QKRSLH 2062 + T N +S + D G+ + S+ + K+ LT +++S +++ Sbjct: 2919 SNKETANLQERSISNDDGEEKIVTSVRRRGRK------PKRSLTVSDDAESSEPERKRQK 2972 Query: 2063 SVSEERTD--EMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDL 2110 SVS+ D E E E+EE + + T+S+ S + SK L P + Sbjct: 2973 SVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRSKTQLSPSI 3022 Score = 33.5 bits (75), Expect = 2.4 Identities = 48/212 (22%), Positives = 83/212 (39%), Gaps = 32/212 (15%) Query: 2013 TPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEM 2072 TP S NV ++ ++I N+E S +S + KT ++ K+ S+ TD Sbjct: 190 TPGPSANVANDAMSILETITSLNQEASAARASTETSNAKTSERASKKL---PSQPTTDTS 246 Query: 2073 THKETNEQE--ERLLATASFTKSSRSSRTRSSKAILLPD--------LSEPNNEPLFSP- 2121 T KE ++ ++ +TA + +S + LP E NN L + Sbjct: 247 TDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKD 306 Query: 2122 ----ASEVPRKAKAKKIEVP------AQLKELVSDLSSQFVISPPALRSRQKNTSNKNKL 2171 +SE K+ K + P + KE +F K + + K+ Sbjct: 307 VQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKF--------DHSKKSEDTQKV 358 Query: 2172 EDELKDDAQSVETLGKPKAKRIRTSKTKQASK 2203 +DE + + VE+L P K +KT + +K Sbjct: 359 KDEKQAKEKEVESLKLPSEKNSNKAKTVEGTK 390 Score = 32.3 bits (72), Expect = 5.4 Identities = 40/203 (19%), Positives = 81/203 (39%), Gaps = 8/203 (3%) Query: 1716 KTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVR-- 1773 KT+ ET++ T V + D SS T + QN + QE + + G+ + Sbjct: 2823 KTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYP 2882 Query: 1774 -KKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVN-QDILENTSSVEQ 1831 + T K K+ S+ I + + Q+ + V K+ N Q+ + E+ Sbjct: 2883 VETTLKMKDDSKTDTGIVT----VEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEE 2938 Query: 1832 ELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDL 1891 ++ + R ++ K S + E + + + SV+ + ++ + +E E ++ Sbjct: 2939 KIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEP 2998 Query: 1892 KVSTVTSPSRMIRKLRSTNLDAS 1914 +T S +R + T L S Sbjct: 2999 SGATTRSTTRSEAQRSKTQLSPS 3021 >gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] Length = 710 Score = 58.9 bits (141), Expect = 5e-08 Identities = 136/665 (20%), Positives = 254/665 (38%), Gaps = 85/665 (12%) Query: 1604 EPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEP 1663 +P + A+SD +N ATE K E G ++ + +KV L + Sbjct: 97 QPAEKATSDEKDSVSNIATEIK-----EGQQSGTVSPQKQSAQKVIFKKKVSLLN-IATR 150 Query: 1664 IKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPT--KLVKSAFK-TAQE 1720 I + K SK + T S T + + C T + A K T E Sbjct: 151 IMGGGKSGTVSSQKQPASKTASDKT--DSALNTATEIKDGLQCGTVSSQKQQALKATTDE 208 Query: 1721 TSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVR----KKT 1776 +++ +++ D S T Q+ + S ++++ +++ K G+ R +K Sbjct: 209 EGSVSNIATEIKDGEKSGT-VSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKP 267 Query: 1777 RKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQIT 1836 K S +++ + R ++ S G + +D L N + ++ Sbjct: 268 PALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKN---- 323 Query: 1837 TGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTV 1896 G +++R+ S + +PA++ T+ ++ S++T+ ++ EI KVS+ Sbjct: 324 -GEKTRRVSSRK--KPALKATSDEKDSFSNITR-----------GKKDGEISR--KVSSQ 367 Query: 1897 TSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLES 1956 P+ L+ T+ + G +++K +K + V + + S +DS L Sbjct: 368 KPPT-----LKGTSDEEDSVLGIARENKDGEKS---RTVSSEKPPGLKASSDEKDSVLNI 419 Query: 1957 SQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAK 2016 ++ E RK+ + +D S +E KK+ R+ S++ PA Sbjct: 420 ARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE-----KKDGEISRKVSSQKPPAL 474 Query: 2017 SENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTH-- 2074 D LG + + E S +SS+K K S + L+ ++ E T Sbjct: 475 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 534 Query: 2075 --------KETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVP 2126 K T+++++ +L A K SRT SS+ +P + + VP Sbjct: 535 SSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ-------KQPALKAICDKEDSVP 587 Query: 2127 RKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLG 2186 A KK E ++ +SSQ PAL++ + + + E+KD QS G Sbjct: 588 NMATEKKDE------QISGTVSSQ---KQPALKATSDKKDSVSNIPTEIKDGQQS----G 634 Query: 2187 KPKAKRIRTSKTKQASKNTEKESAWSPPPIEIR-LISPLASPADGVKSKPRKT-----TE 2240 +++ K K++ A +IR +SP A V K + + T Sbjct: 635 TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATR 694 Query: 2241 VTGTG 2245 +TG G Sbjct: 695 ITGGG 699 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 55.8 bits (133), Expect = 5e-07 Identities = 76/326 (23%), Positives = 130/326 (39%), Gaps = 31/326 (9%) Query: 1762 VATPKMPGQSVRKKTRKAKEIS-EASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQ 1820 V K Q ++ + RK K+ E +E I V + + P+ S++PRR R+ Sbjct: 223 VPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVE--RRRSRSPRRSLSPRRSPRRSRSRS 280 Query: 1821 DILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVE 1880 E S + RE +R K Q LE +E K+ + S+ + RR RS E Sbjct: 281 HHREGHGSSSFD------RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRE 334 Query: 1881 NQESVEIINDLKVSTVTSPSRMIRKL---RSTNLDASENTGNKQDDKSSDKQLRIKHVRR 1937 S D K ++ R + D + GN+++ + + R K +R Sbjct: 335 RHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKE-QR 393 Query: 1938 VRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSP 1997 RG EV +ED + + + R R R RK + S A K RS Sbjct: 394 SRG-EVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERK-HRSRSRSRNAGKRSRSR 451 Query: 1998 KKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQ 2057 K+++ + S + +S + G+ V SKK+ ++ +S+ Sbjct: 452 SKEKSSKHKNESKEKSNKRSRSGSQGRT-------------DSVEKSKKREHSPSKEKSR 498 Query: 2058 KRSLHSVSEERTDEMTHKETNEQEER 2083 KRS S+ER+ + H ++ +Q ++ Sbjct: 499 KRSR---SKERSHKRDHSDSKDQSDK 521 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 55.5 bits (132), Expect = 6e-07 Identities = 97/474 (20%), Positives = 173/474 (36%), Gaps = 59/474 (12%) Query: 1751 VKSAQQEASADVATPKMPGQSVRKKTRKAKE-----ISEASENIYSDV-RGLSQNQQIPQ 1804 +K ++ AT Q V +KT++ E + + EN S + S+ Q Sbjct: 127 LKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQ 186 Query: 1805 NSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKV 1864 NS T + +K+ +N+ E T K LK S+ + E + Sbjct: 187 NSKTVSKNCSQKDKKDS--KNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSE---- 240 Query: 1865 SSVTKRTPRRIKRSVENQESVEIINDLK-VSTVTSPSRMIRKLRSTNLDASENTGNKQDD 1923 +S+ + +S + ES+ L+ S S + ++ + T D +N D Sbjct: 241 NSLNVDFLMLVGQS--DDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDA 298 Query: 1924 KSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPS 1983 +S D + K ++V+ + V D ++D ++ + AE S RK + K Sbjct: 299 ESEDSKDAKKDSKKVK-KNVKKDDKKKDVKKDTE--STDAESGDSKDERKDTKKDKKKLK 355 Query: 1984 EDVGSKAVKEERSPKKKEAPSIR--RRSTRNTPAKSENVDVGKPALGKSILVPNEELSMV 2041 +D K K+ E+ + R +RN S+N D K A Sbjct: 356 KDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDA--------------- 400 Query: 2042 MSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRS 2101 KK+T T+S+S+ S S +E+ D+ K N++ K+ S Sbjct: 401 ----KKITFSTDSESELESKESQKDEKKDKKDSKTDNKKS---------VKNDEESTDAD 447 Query: 2102 SKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELV--SDLSSQFVISPPALR 2159 SEP + E K +KK + K+ +++ S + Sbjct: 448 ---------SEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH 498 Query: 2160 SRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSP 2213 S++K S K+ +D KD + + +TS + S +ES + P Sbjct: 499 SKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKP 552 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 52.4 bits (124), Expect = 5e-06 Identities = 116/563 (20%), Positives = 209/563 (37%), Gaps = 99/563 (17%) Query: 1675 VIKDTRSKEITSDTMEQSIHETIPL--VSQNIMCPTKLV-----KSAFKTAQETSTMTMN 1727 V K + K +SD+ + S E ++ P K V K+A K ++ +S+ Sbjct: 74 VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEES- 132 Query: 1728 VSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASE 1787 S DD K Q +Q K + +A A A PK KAK S+ Sbjct: 133 -SDDDDEEDQKK----QPVQ----KGVKPQAKAAKAPPK-----------KAKSSDSDSD 172 Query: 1788 NIYSDVRGLSQNQQIP------QNSVTPRRGRRKKEV-NQDILENTSSVEQELQITTGRE 1840 + D +Q +I Q P+ R ++ N ++SS E Sbjct: 173 SSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEE 232 Query: 1841 SKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLK-------- 1892 K + + P + K VK ++ TP R S E+ S E K Sbjct: 233 EKAAATPKKTVPKKQVVAKAPVKAAT----TPTRKSSSSEDSSSDEEEEQKKPMKNKPGP 288 Query: 1893 VSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDS 1952 S+V PS K ++ G + K+ +KQ + V E S SD + S Sbjct: 289 YSSVPPPSAPPPK---------KSLGTQPPKKAVEKQ------QPVESSEDS-SDESDSS 332 Query: 1953 NLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRN 2012 + E + +A + + + S+ S + +++ +P K P+ +++ N Sbjct: 333 SEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSK---PAGTTKNSSN 389 Query: 2013 TPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEM 2072 PA + KPA V +K LT+K +S S + S EE+T +M Sbjct: 390 KPAVTTKSPAVKPAAAPK--------QPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKM 441 Query: 2073 THKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAK 2132 + + + ++ + SR SS D ++E S+ K K + Sbjct: 442 VATTKPKATAKAALSLPAKQAPQGSRDSSS------DSDSSSSEEEEEKTSKSAVKKKPQ 495 Query: 2133 KIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKR 2192 K+ A + P + + + +SN + +D +++ + ++ G P+ + Sbjct: 496 KVAGGAAPSK------------PASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQA 543 Query: 2193 IR-------TSKTKQASKNTEKE 2208 + T++ +A+KN+E+E Sbjct: 544 PKANGTSALTAQNGKAAKNSEEE 566 Score = 40.4 bits (93), Expect = 0.020 Identities = 87/512 (16%), Positives = 177/512 (34%), Gaps = 21/512 (4%) Query: 1639 ANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIP 1698 A + +S++ S D +P++ + K K +SD+ S E P Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQA-KAAKAPPKKAKSSDSDSDSSSEDEP 179 Query: 1699 LVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEA 1758 +Q VK+ K + + ++ SS + + + + A Sbjct: 180 PKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239 Query: 1759 SADV----ATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRR 1814 V K P ++ TRK+ ++S + + + +N+ P +SV P Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPP 299 Query: 1815 KKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRR 1874 K+ + +VE++ + + +S S E E+ + VS T + P Sbjct: 300 PKK-SLGTQPPKKAVEKQQPVESSEDSSDESDSSSEE---EKKPPTKAVVSKATTKPPPA 355 Query: 1875 IKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKH 1934 K + + +S + + + P+ + S+N A ++ KQ + Sbjct: 356 KKAAESSSDSSDSDSSEDDEAPSKPAGTTKN--SSNKPAVTTKSPAVKPAAAPKQ-PVGG 412 Query: 1935 VRRVRGREVSPSDVREDSNLESSQLTVQAEFDMS---------AIPRKRGRPRKINPSED 1985 +++ R+ S E+S+ + T + ++P K+ + S D Sbjct: 413 GQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSD 472 Query: 1986 VGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSK 2045 S + +EE K A + + A S+ K S +++ S K Sbjct: 473 SDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532 Query: 2046 KKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAI 2105 K Q+ K + S + + E+EE+ A +KS + + ++A Sbjct: 533 LKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA 592 Query: 2106 LLPDLSEPNNEPLFSPASEVPRKAKAKKIEVP 2137 + + L +P + RK K+ P Sbjct: 593 KEAETPQAKKIKLQTPNTFPKRKKGEKRASSP 624 Score = 32.7 bits (73), Expect = 4.2 Identities = 51/227 (22%), Positives = 85/227 (37%), Gaps = 36/227 (15%) Query: 2035 NEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSS 2094 + +LS V + K T T+ + SL + K E +L A K + Sbjct: 24 DNQLSEVANKFAKATGATQQDANASSLLDIYS-----FWLKSAKVPERKLQANGPVAKKA 78 Query: 2095 RSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVIS 2154 + + S D SE E PA KK VPA+ L Sbjct: 79 KKKASSSDSE----DSSEEEEEVQGPPA---------KKAAVPAKRVGL----------- 114 Query: 2155 PP---ALRSRQKNTSNKNKLEDELKDDA-QSVETLGKPKAKRIRT--SKTKQASKNTEKE 2208 PP A ++ + ++S ++ +D+ +D Q V+ KP+AK + K K + +++ Sbjct: 115 PPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSS 174 Query: 2209 SAWSPPPIEIRLISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSS 2255 S PP + I+P+ A K+ P+ G+ SS Sbjct: 175 SEDEPPKNQKPKITPVTVKAQ-TKAPPKPARAAPKIANGKAASSSSS 220 >gi|153945728 microtubule-associated protein 1B [Homo sapiens] Length = 2468 Score = 52.4 bits (124), Expect = 5e-06 Identities = 73/332 (21%), Positives = 128/332 (38%), Gaps = 32/332 (9%) Query: 1842 KRLKSSQLLEPAVEETTKKEVKVSS------VTKRTPRRIKRSVENQESVEIINDLKVST 1895 +R S + L+PA + K V+ S VTK VE++E V + D + T Sbjct: 537 QRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKT 596 Query: 1896 VTSPSRMIRKLRSTN--LDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSN 1953 T PS +++ S KQ K + K V+ + +V P D +E+ Sbjct: 597 ETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVK--KETKVKPEDKKEEK- 653 Query: 1954 LESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEE-RSPKKKEAPSIRRRSTRN 2012 E + V + D + I +K +P+K ++V + KEE + PKK+ + + Sbjct: 654 -EKPKKEVAKKEDKTPI-KKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKK 711 Query: 2013 TPAKSENVDVGK------------PALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRS 2060 K E +V K P K P E + K K+ KK ES + Sbjct: 712 EVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSV 771 Query: 2061 LHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFS 2120 +E+ K+ + E + A ++ + + A + P L S Sbjct: 772 AAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMS 831 Query: 2121 PASEVPR---KAKAKKIEVPAQLK---ELVSD 2146 ++ + + KA++++V +K EL+ D Sbjct: 832 SPEDLTKDFEELKAEEVDVTKDIKPQLELIED 863 Score = 37.7 bits (86), Expect = 0.13 Identities = 47/269 (17%), Positives = 106/269 (39%), Gaps = 26/269 (9%) Query: 1867 VTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSS 1926 +T + P + + + ++ + LK + PS+ +RK ++ E T Sbjct: 521 LTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRK------ESKEETPEVTKVNHV 574 Query: 1927 DKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDV 1986 +K +++ +V ++ P ++ ++ ++ V ++ + S + + + + DV Sbjct: 575 EKPPKVESKEKVMVKKDKP--IKTETKPSVTEKEVPSKEEPSPVKAEVAEKQ----ATDV 628 Query: 1987 GSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKK 2046 KA KE+ K+ + ++ + P K K + K EE+ KK Sbjct: 629 KPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEV------KK 682 Query: 2047 KLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAIL 2106 ++ K+ + + +K V +E + KE ++E++ K + + K Sbjct: 683 EVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKK-----EVKKEEKEPKKEIKK--- 734 Query: 2107 LPDLSEPNNEPLFSPASEVPRKAKAKKIE 2135 LP ++ ++ PL K K K E Sbjct: 735 LPKDAKKSSTPLSEAKKPAALKPKVPKKE 763 Score = 35.4 bits (80), Expect = 0.64 Identities = 102/528 (19%), Positives = 190/528 (35%), Gaps = 78/528 (14%) Query: 1244 PGAADDSKLEVFTTPKKCAVPVETEWLKSKD---RTTSFFLNSPEKEHQEMDEGSQSLEK 1300 P S L K AVPV E+ +KD R + ++ P + + E S + Sbjct: 1340 PTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSPMDEPVPDSESPIEKVLSPLR 1399 Query: 1301 LDVSKGNSSV--SITSDETTLEYQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKD 1358 G+ S S S + + A SP + + + S + +T+ Q +++ Sbjct: 1400 SPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQGSPDQVSPVSEMTSTSLYQDKQE 1459 Query: 1359 GDKDVFASEVTPSDLQKQMGNLEDAETKDLLVAAEAFSELNHLSPVQ------GTEASLC 1412 G FA +K+ ++E ++ L E +L +SP Q G+ Sbjct: 1460 GKSTDFAPIKEDFGQEKKTDDVEAMSSQPALALDER--KLGDVSPTQIDVSQFGSFKEDT 1517 Query: 1413 APSVYEGKIFTQKSKVPVLDEGLTSVETYTPAIRANDNKSMADVLGDGGNSSLTISEGPI 1472 S+ EG + + KS PV DEG+ A D S + + +S+ S P Sbjct: 1518 KMSISEGTV-SDKSATPV-DEGV-----------AEDTYSHMEGVASVSTASVATSSFPE 1564 Query: 1473 VSERRLNQEVALNLKEDHEVEV------GVLKESVDLPEEKL---------PISDSPPDT 1517 + ++ + + H EV V++ E ++ P+S SPPD Sbjct: 1565 PTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDF 1624 Query: 1518 QEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECD 1577 + ++ S + + ++ F + P +L + ++ + D Sbjct: 1625 SPKTAKSRTPVQDHRSEQSSMSIEFGQESPEQSLAMDFSRQSPDHPTVGA---------- 1674 Query: 1578 IAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAA----------NTATEEKLV 1627 G L + ++ T E + P D S + K N +E V Sbjct: 1675 -----GVLHITENGPT------EVDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISV 1723 Query: 1628 CSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLL-DVIKDTRSKEIT- 1685 E A+ PS + S + DTL V P +++ +L + ++ ++++ Sbjct: 1724 SQVEASPSTSSAHTPSQIASPLQE---DTLSDVAPPRDMSLYASLTSEKVQSLEGEKLSP 1780 Query: 1686 -SDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVD 1732 SD + E+ PL S T VK T +S+ ++ + + Sbjct: 1781 KSDISPLTPRESSPLYSPTFSDSTSAVKEKTATCHSSSSPPIDAASAE 1828 Score = 33.9 bits (76), Expect = 1.9 Identities = 48/236 (20%), Positives = 91/236 (38%), Gaps = 31/236 (13%) Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATAS-F 2090 +V +L S++ L K +S+ S+E T E+T E+ ++ + Sbjct: 529 VVKQTKLKQRADSRESL-KPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVM 587 Query: 2091 TKSSRSSRTRSSKAIL---LPDLSEPNN---EPLFSPASEV-PRKAKAKKIEVPAQLKEL 2143 K + +T + ++ +P EP+ E A++V P+ AK K ++ ++K Sbjct: 588 VKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKP- 646 Query: 2144 VSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASK 2203 +K K K E K+D ++ KPK + ++ K+ K Sbjct: 647 ----------------EDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKK 690 Query: 2204 NTEKESAWSPPPIEIRLISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQ 2259 +KE P E++ +P VK + +K + + KKL K+ Sbjct: 691 EEKKE-----PKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKK 741 Score = 33.5 bits (75), Expect = 2.4 Identities = 94/583 (16%), Positives = 223/583 (38%), Gaps = 62/583 (10%) Query: 1652 QKVDTLPYVPEPI---KVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPT 1708 +K+ L ++ +P+ K + V+K T+ K+ +D+ E PL S+++ + Sbjct: 503 EKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQ-RADSRESLKPAAKPLPSKSVRKES 561 Query: 1709 KLVKSAFKTAQETSTMT-MNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKM 1767 K +ET +T +N + V SK + ++ + + ++ +V + + Sbjct: 562 K---------EETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEE 612 Query: 1768 PG----QSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDIL 1823 P + K+ K + + + + + ++++ + P++ KKE I Sbjct: 613 PSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKK--EEKEKPKKEVAKKEDKTPIK 670 Query: 1824 ENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQE 1883 + ++E++ +E K+ + + + +ET KEVK K + K+ V+ +E Sbjct: 671 KEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVK-----KEVKKEEKKEVKKEE 725 Query: 1884 SVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDK--SSDKQLRIKHVRRVRGR 1941 P + I+KL DA +++ + K ++ K K V+ Sbjct: 726 K-------------EPKKEIKKLPK---DAKKSSTPLSEAKKPAALKPKVPKKEESVKKD 769 Query: 1942 EVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKE 2001 V+ +E ++ + +A ++A + + + + +E ++ Sbjct: 770 SVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSL 829 Query: 2002 APSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEE-------LSMVMSSKKKLTKKTES 2054 S + K+E VDV K + L+ +EE + + K++ K + Sbjct: 830 MSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPA 889 Query: 2055 QSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPN 2114 +S + + E E T +E E++ + + + SS+ + Sbjct: 890 ESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSE-------TGDY 942 Query: 2115 NEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDE 2174 E + +E P + + + V A D S + +R ++++ ++ + +E Sbjct: 943 EEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEE 1002 Query: 2175 LKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIE 2217 D+A + K +A++ ++ +E + P +E Sbjct: 1003 DMDEA-----IEKGEAEQSEEEADEEDKAEDAREEEYEPEKME 1040 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 51.6 bits (122), Expect = 9e-06 Identities = 84/523 (16%), Positives = 203/523 (38%), Gaps = 71/523 (13%) Query: 1710 LVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPG 1769 L K +ET + + ++ S + +GQ+ + + E D Sbjct: 67 LEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED-------- 118 Query: 1770 QSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSV-TPRRGRRKKEVNQDILENTSS 1828 K K+K+ ++ +YS ++P+ + ++ +K + +++ +N+ Sbjct: 119 -----KDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK 173 Query: 1829 VEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEII 1888 +++ +I + ES +S + L+ ++K K + K P I+ E+ ++ Sbjct: 174 IKERSRINSSGESGD-ESDEFLQ------SRKGQKKNQKNKPGPN-IESGNEDDDA---- 221 Query: 1889 NDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDV 1948 K+ TV + E K+D++ + +R+++ +E + Sbjct: 222 -SFKIKTVAQKKA----------EKKERERKKRDEEKAK-------LRKLKEKEELETGK 263 Query: 1949 REDSNLESSQLTVQAE-------FDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKE 2001 ++ S + SQ + E D IP + +ED K++ KKK Sbjct: 264 KDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG 323 Query: 2002 APSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSL 2061 + + + P+K+ V + AL K + EE ++++ + E +++++ Sbjct: 324 EKEEKEKEKKKGPSKA-TVKAMQEALAK---LKEEEERQKREEEERIKRLEELEAKRKEE 379 Query: 2062 HSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDL---------SE 2112 + +E+ + KE +E TKS R +R R+ + L S Sbjct: 380 ERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSL 439 Query: 2113 PNNEPLF--SPASEVPRKAKAKKIEVPAQL---KELVSDLSSQFVISPPALRSRQKNTSN 2167 P P++ ++P++ ++K++ +L E++ + +PP + ++ + Sbjct: 440 PKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTE 499 Query: 2168 KNKLED--ELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKE 2208 L+D + D ++ + G ++ + ++ + E+E Sbjct: 500 DAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEE 542 Score = 32.7 bits (73), Expect = 4.2 Identities = 64/359 (17%), Positives = 126/359 (35%), Gaps = 47/359 (13%) Query: 1737 SKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGL 1796 SK + ++ + VKS V T +P + +T A E + D + Sbjct: 267 SKQKESQRKFEEETVKS-----KVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKK 321 Query: 1797 SQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEE 1856 ++ + ++G K V + E + +++E + E +R+K + LE +E Sbjct: 322 KGEKE--EKEKEKKKGPSKATVKA-MQEALAKLKEEEERQKREEEERIKRLEELEAKRKE 378 Query: 1857 TTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASEN 1916 + E + R K+ E + + + K+ +T R R L + Sbjct: 379 EERLE--------QEKRERKKQKEKERKERLKKEGKL--LTKSQREARARAEATLKLLQA 428 Query: 1917 TGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGR 1976 G + K S + R + + R+ P + ES +L E +P K Sbjct: 429 QGVEVPSKDSLPKKR--PIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEET 486 Query: 1977 PRKINPSED-----------------------VGSKA-VKEERSPKKKEAPSIRRRSTRN 2012 P + P E+ G+K ++ + +P+++E Sbjct: 487 PPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEE 546 Query: 2013 TPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDE 2071 + + E + + G +E++S S K L KK + S + ++RT E Sbjct: 547 SEEEEEEEGESEGSEGDE---EDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKE 602 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 50.4 bits (119), Expect = 2e-05 Identities = 96/448 (21%), Positives = 167/448 (37%), Gaps = 52/448 (11%) Query: 1773 RKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQE 1832 +++ + K S ++ D R + + + R RR+K + +S V +E Sbjct: 133 QRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRE 192 Query: 1833 LQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLK 1892 + + R + S+ PA E KKE +TP + SV+ + + Sbjct: 193 RKRSHSRSPRHRTKSRSPSPAPE---KKE--------KTPELPEPSVK-------VKEPS 234 Query: 1893 VSTVTSPSRMIRKLRSTNL-DASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVRED 1951 V TS S +++ + + + E + K K +K+ K R R R S S R Sbjct: 235 VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKE---KTRPRSRSRSKSRSRTRSR 291 Query: 1952 SNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTR 2011 S + S PR+R PR+ PS + + P+ + + S RR R Sbjct: 292 SPSHTRPRRRHRSRSRSYSPRRRPSPRR-RPSPRRRTPPRRMPPPPRHRRSRSPVRRRRR 350 Query: 2012 NTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERT-- 2069 ++ + S + + +S P + S +K + + S S R H S T Sbjct: 351 SSASLSGSSSSSSSSRSRS--PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP 408 Query: 2070 DEMTHKETNEQEERLLATASFTKSSRSSRT--RSSKAILLPDLSEPNNEPLFSPASEVPR 2127 + H T +Q R T+ SR S + R+S + +E P SPA + PR Sbjct: 409 PKTRHSPTPQQSNR-------TRKSRVSVSPGRTSGKVTKHKGTEKRESP--SPAPK-PR 458 Query: 2128 KAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGK 2187 K +L E D + + + RQ N+ D + E + Sbjct: 459 K---------VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE---R 506 Query: 2188 PKAKRIRTSKTKQASKNTEKESAWSPPP 2215 PK ++ + + +++ SA SP P Sbjct: 507 PKRSHVKNGEVGRRRRHSPSRSA-SPSP 533 Score = 41.6 bits (96), Expect = 0.009 Identities = 74/327 (22%), Positives = 126/327 (38%), Gaps = 62/327 (18%) Query: 1912 DASENTGNKQDDKSS-DKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAI 1970 D ++ +K++ +SS +K+ R + RR + R SP SS + + + S Sbjct: 148 DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP-------RRRSSPVRRERKRSHSRS 200 Query: 1971 PRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRR--STRNTPAKSENVDVGKPALG 2028 PR R + R +P+ + K+E++P+ E PS++ + S + + S+ + V KP Sbjct: 201 PRHRTKSRSPSPAPE------KKEKTPELPE-PSVKVKEPSVQEATSTSDILKVPKP--- 250 Query: 2029 KSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATA 2088 + I P E S K+K +KT +S+ RS S RT + T + + Sbjct: 251 EPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSK---SRSRTRSRSPSHTRPRRRHRSRSR 307 Query: 2089 SFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLS 2148 S++ R S P P SP P +++ P + + S Sbjct: 308 SYSPRRRPS---------------PRRRP--SPRRRTP----PRRMPPPPRHRRSRS--- 343 Query: 2149 SQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKE 2208 P R R+ + S + S + PK RTS + T + Sbjct: 344 -------PVRRRRRSSASLSGS-----SSSSSSSRSRSPPKKPPKRTSSPP---RKTRRL 388 Query: 2209 SAWSPPPIEIRLISPLASPADGVKSKP 2235 S + PP SP A+P + P Sbjct: 389 SPSASPPRRRHRPSPPATPPPKTRHSP 415 Score = 39.7 bits (91), Expect = 0.034 Identities = 79/407 (19%), Positives = 149/407 (36%), Gaps = 49/407 (12%) Query: 1764 TPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQ-NSVTPRRGRRKKEVNQDI 1822 TP++P SV+ K +E + S D+ + + + IP+ +P + +K++ + Sbjct: 220 TPELPEPSVKVKEPSVQEATSTS-----DILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT 274 Query: 1823 LENTSSVEQELQITTGRES-----KRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKR 1877 + S + T R +R S+ + + S + PRR+ Sbjct: 275 RPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP 334 Query: 1878 SVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQ---LRIKH 1934 ++ S SP R R+ S +L S ++ + +S K+ Sbjct: 335 PPRHRRS------------RSPVRR-RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381 Query: 1935 VRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVG--SKAVK 1992 R+ R S S R + S T + S P++ R RK S G S V Sbjct: 382 PRKTRRLSPSASPPRR-RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440 Query: 1993 EERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKT 2052 + + +K+E+PS + + ++SE GK A S+ +++ ++ Sbjct: 441 KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV-----------QQRRQYRRQN 489 Query: 2053 ESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSE 2112 + S S SE+ + +H + E R + S +S S R R + + Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS-RSASPSPRKRQKE-------TS 541 Query: 2113 PNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALR 2159 P SP+ R+ ++ P + + + + SPP R Sbjct: 542 PRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588 >gi|42560244 peptidylprolyl isomerase G [Homo sapiens] Length = 754 Score = 50.1 bits (118), Expect = 3e-05 Identities = 86/441 (19%), Positives = 165/441 (37%), Gaps = 60/441 (13%) Query: 1769 GQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSS 1828 GQ V ++ K ++A+ +++VR LS + IP++ V KKE + ++SS Sbjct: 147 GQEVVREIENQK--TDAASKPFAEVRILSCGELIPKSKV-------KKEEKKRHKSSSSS 197 Query: 1829 VEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEII 1888 + +S+ S E A EE +KK K R ++ K+ + + Sbjct: 198 SSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASS 257 Query: 1889 NDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDV 1948 + P +R + + K K+ +K+ K+ R R RE +P + Sbjct: 258 ESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER--KNRERERERECNPPN- 314 Query: 1949 REDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRR 2008 + A + + + GR K R P++ PS R Sbjct: 315 -----------SQPASYQRRLLVTRSGRKIK--------------GRGPRRYRTPS--RS 347 Query: 2009 STRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEER 2068 +R+ +SE + + ++ M +SS ++ K K L+ + E + Sbjct: 348 RSRDRFRRSETPPHWRQEMQRA-------QRMRVSSGERWIK-----GDKSELNEIKENQ 395 Query: 2069 TDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRK 2128 + KE + R ++ + K+ + + + K+ N+E ++V ++ Sbjct: 396 RSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKR 455 Query: 2129 AKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKP 2188 AK+K + + S +RSR K ++N E E + D+ Sbjct: 456 AKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDS--------- 506 Query: 2189 KAKRIRTSKTKQASKNTEKES 2209 K K S++K+ SK E +S Sbjct: 507 KGKDQERSRSKEKSKQLESKS 527 Score = 40.4 bits (93), Expect = 0.020 Identities = 66/333 (19%), Positives = 129/333 (38%), Gaps = 48/333 (14%) Query: 1781 EISEASENIYSDVRGLSQNQQIPQN-SVTPRRGRRKKEVNQDILENTSSVEQELQITTGR 1839 E++E EN S VR + +N S +P R K++ +D ++S E++++ + + Sbjct: 387 ELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKD--HKSNSKERDIRRNSEK 444 Query: 1840 ESK-----RLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIK-----RSVENQESVEIIN 1889 + K + ++ +E +K + + S + +R++ R EN + E + Sbjct: 445 DDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQS 504 Query: 1890 DLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVR 1949 D K SR K + ++E+ +K +K Q R + +G+ S R Sbjct: 505 DSKGKD-QERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563 Query: 1950 EDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRS 2009 E S V++ R R R SK R + + R R Sbjct: 564 ERSRSRDRSRRVRSR------THDRDRSR---------SKEYHRYREQEYRRRGRSRSRE 608 Query: 2010 TRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERT 2069 R P +S + D + + +++ ESQS+ + + E ++ Sbjct: 609 RRTPPGRSRSKDRRR-----------------RRRDSRSSEREESQSRNKDKYRNQESKS 651 Query: 2070 DEMTHKETNEQEERLLATASFTKSSRSSRTRSS 2102 KE +E E+R+ + + SS +SR + + Sbjct: 652 SH--RKENSESEKRMYSKSRDHNSSNNSREKKA 682 Score = 34.7 bits (78), Expect = 1.1 Identities = 55/287 (19%), Positives = 108/287 (37%), Gaps = 17/287 (5%) Query: 1774 KKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQEL 1833 KK K+K S++ E S R N+ + + +GR + V + ++ S Sbjct: 453 KKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSK----- 507 Query: 1834 QITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKV 1893 G++ +R +S + + ++ + + S R + R + + N Sbjct: 508 ----GKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563 Query: 1894 STVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSN 1953 S R R++RS D + + +K+ + +++ R + R R R P R Sbjct: 564 ERSRSRDRS-RRVRSRTHD-RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDR 621 Query: 1954 LESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNT 2013 + + +E + S K K E S + S K+ + S S+ N+ Sbjct: 622 RRRRRDSRSSEREESQSRNK----DKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNS 677 Query: 2014 PAKSENVDVGKPALGKSILVPNEELSMVMSSK--KKLTKKTESQSQK 2058 K + D + K NE S ++ +K +K+ E ++QK Sbjct: 678 REKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQK 724 >gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1 [Homo sapiens] Length = 1828 Score = 50.1 bits (118), Expect = 3e-05 Identities = 55/226 (24%), Positives = 94/226 (41%), Gaps = 29/226 (12%) Query: 2041 VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR 2100 +M +K K ++ S S HS SEE + + ++ ++ + ++S+ SS + Sbjct: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60 Query: 2101 SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS 2160 S+ SE +E S + V +AK K PA KE ++D+ + P Sbjct: 61 ESQ-------SESESESAGSKSQPVLPEAKEK----PASKKERIADVKKMWEEYPDVYGV 109 Query: 2161 RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIR----TSKTKQASKNTEKESAWS---- 2212 R+ N S + +K++A S G PK + R K KQ E+E S Sbjct: 110 RRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESE 169 Query: 2213 PPPIEIRLISPL---ASPADGVKSKPRKTTEVTGTGLGRNRKKLSS 2255 P +++ P+ P VK +P+ T G+ +K+ SS Sbjct: 170 PEQKKVKARRPVPRRTVPKPRVKKQPK-------TQRGKRKKQDSS 208 >gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] Length = 1226 Score = 50.1 bits (118), Expect = 3e-05 Identities = 105/516 (20%), Positives = 199/516 (38%), Gaps = 88/516 (17%) Query: 1703 NIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADV 1762 N+ C K F+ ++ + ++ + VV+ + + +NV ++E ++ Sbjct: 381 NVKCAYKKYLYGFEEYCRSANIEFQMALPEKVVNKQCK----ECENVKEIKVKEENETEI 436 Query: 1763 ATPKMPGQS--VRKKTRKAKEISEASENIYSDVRGLSQN--QQIPQNSVTPRRGRRKKEV 1818 KM + + ++ + ++ E ENI + G +N + IP +S + KK Sbjct: 437 KEIKMEEERNIIPREEKPIEDEIERKENIKPSL-GSKKNLLESIPTHSDQEKEVNIKKPE 495 Query: 1819 NQDILEN----TSSVEQELQITTGRESKRLKSS--------QLLEPAVEETTK------- 1859 + + L++ T+ V++ L I E ++ KS +++ PA + K Sbjct: 496 DNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGYDEWIKADKIVRPADKNVPKIKHRKKI 555 Query: 1860 ---------KEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTV-TSPSRMIRKLRST 1909 K+ K S + R K + S E+++ L ++ S + I+ + T Sbjct: 556 KNKLDKEKDKDEKYSPKNCKLRRLSKPPFQTNPSPEMVSKLDLTDAKNSDTAHIKSIEIT 615 Query: 1910 N----LDASENT----------GNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLE 1955 + L ASE++ G + D + ++ +I H+ R +S + S LE Sbjct: 616 SILNGLQASESSAEDSEQEDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLE 675 Query: 1956 SSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPA 2015 ++ V A+ +S K P ++ +V + E+ ++ E R+ ++T Sbjct: 676 ENK--VHADLVISKPVSKS--PERLRKDIEV----LSEDTDYEEDEVTKKRKDVKKDTTD 727 Query: 2016 KSENVDVGKPALGKSILVPNEELSMVMSSKKK--LTKKTESQSQKRSLHSVSEERTDEMT 2073 KS + + GK EE S KK K ES + S +S S+E +E Sbjct: 728 KSSKPQIKR---GKRRYCNTEECLKTGSPGKKEEKAKNKESLCMENSSNSSSDEDEEETK 784 Query: 2074 HKETN-------EQEERLLATASF------TKSSRSSRTRSSKAILLPDLSEPNNEPLFS 2120 K T E++ + L T F R +S L ++ + S Sbjct: 785 AKMTPTKKYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLLNNSDERLQNSRAKDRKDVWSS 844 Query: 2121 PASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPP 2156 + P+K LKEL SD ++ SPP Sbjct: 845 IQGQWPKKT----------LKELFSDSDTEAAASPP 870 >gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2 [Homo sapiens] Length = 501 Score = 50.1 bits (118), Expect = 3e-05 Identities = 55/226 (24%), Positives = 94/226 (41%), Gaps = 29/226 (12%) Query: 2041 VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR 2100 +M +K K ++ S S HS SEE + + ++ ++ + ++S+ SS + Sbjct: 1 MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60 Query: 2101 SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS 2160 S+ SE +E S + V +AK K PA KE ++D+ + P Sbjct: 61 ESQ-------SESESESAGSKSQPVLPEAKEK----PASKKERIADVKKMWEEYPDVYGV 109 Query: 2161 RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIR----TSKTKQASKNTEKESAWS---- 2212 R+ N S + +K++A S G PK + R K KQ E+E S Sbjct: 110 RRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESE 169 Query: 2213 PPPIEIRLISPL---ASPADGVKSKPRKTTEVTGTGLGRNRKKLSS 2255 P +++ P+ P VK +P+ T G+ +K+ SS Sbjct: 170 PEQKKVKARRPVPRRTVPKPRVKKQPK-------TQRGKRKKQDSS 208 >gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH polyclonal antibodies [Homo sapiens] Length = 1430 Score = 49.7 bits (117), Expect = 3e-05 Identities = 126/619 (20%), Positives = 217/619 (35%), Gaps = 66/619 (10%) Query: 1613 VLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENL 1672 +L + A T++K EN + N S Q ++K+D + + + E+ Sbjct: 121 LLDRFAQAVTKDKFALESENISEPYFTN--RRTISQQSAEKLDAACGIDKTENGTLFEDQ 178 Query: 1673 LDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVD 1732 +V K+ ++ T S E PL + + K + ST + +D Sbjct: 179 -NVDKEGKALPATGQKANVS-PEQPPLFTHTV-----------KDSDHISTRFLG--SMD 223 Query: 1733 DVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMP--GQSVRKKTRKAKEISEASE--- 1787 + SS+ + + + +K A + A + P G+ +K K S+ + Sbjct: 224 SLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVS 283 Query: 1788 NIYSDVR-----GLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESK 1842 NI ++++ G +Q+ P T + +I E S Q + + Sbjct: 284 NIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVI 343 Query: 1843 RLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQE---SVEIINDLKVSTVTSP 1899 K LL A T + S K+ P + + + EI + L+ TV+S Sbjct: 344 FKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQ 403 Query: 1900 SRMIRKLRSTNLDASENT------GNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSN 1953 + K + D+ N G K SS KQ +K + EDS Sbjct: 404 KQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK-----------ATTDEEDSV 452 Query: 1954 LESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNT 2013 L + E + +K+ + ED S E + +K S R++ Sbjct: 453 LNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKK----- 507 Query: 2014 PAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMT 2073 PA D + + E+S +SS+K K S + L EE+ E + Sbjct: 508 PALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKS 567 Query: 2074 HKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASE----VPRKA 2129 ++EQ L AT K S + R K + +P S+ VP A Sbjct: 568 RTVSSEQPPGLKATRD-EKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMA 626 Query: 2130 KAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPK 2189 K E ++ +SSQ PAL++ + + + E+KD QS + + Sbjct: 627 TETKDE------QISGTVSSQ---KQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ 677 Query: 2190 AKRIRTSKTKQASKNTEKE 2208 TS K + N E Sbjct: 678 LAWKATSVKKDSVSNIATE 696 >gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sapiens] Length = 817 Score = 49.7 bits (117), Expect = 3e-05 Identities = 92/473 (19%), Positives = 170/473 (35%), Gaps = 53/473 (11%) Query: 1716 KTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVK---SAQQEASADVATPKMPGQSV 1772 K +E S ++D + Q Q+ N K S ++ + +PK + Sbjct: 218 KETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKL 277 Query: 1773 RK-----KTRKAKEISEASENIYSDVRGLSQNQQIPQNSV-------TPRRGRRKKEVNQ 1820 ++ K + + +S + I SD L + P + V T +G R E Sbjct: 278 KEISLACKITELESVSLPTPEIQSDF--LHSKVEAPPSEVADTLVIMTASKGVRLPEPKD 335 Query: 1821 DILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVE 1880 ILE + ++ + T E K+ S++ EP K ++ + TP K +++ Sbjct: 336 KILETPQKMTEKSESKTPGEGKKEDKSRMAEPM-----KGYMRPTKSRGLTPLLPKSTIQ 390 Query: 1881 NQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRG 1940 QE + LK + + P + T D + NK+ S +K+ + + Sbjct: 391 EQERHK---QLKSAGIARPEEGRPVVSGTGNDIT-TPPNKELPPSPEKKTKPLATTQPAK 446 Query: 1941 REVSPSDVREDS-----------NLESSQLTVQAEFDMSAIPRK----RGRPRKINPSED 1985 S + + S L +++ + +A P++ RP I PS+D Sbjct: 447 TSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARP-SILPSKD 505 Query: 1986 VGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILV--PNEELSMVMS 2043 V K + + ++P+K+ +PS + + V K ++ P+ + Sbjct: 506 VKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLL 565 Query: 2044 SKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSK 2103 KK KTE + + + D K T+ + T S T + K Sbjct: 566 PKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK 625 Query: 2104 AILLPDLSEPNNEPLF-------SPASEVPRKAKAKKIEVPAQLKELVSDLSS 2149 A +P S P+ P P+S PR ++ LK + S + S Sbjct: 626 ATPMP--SRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGS 676 >gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sapiens] Length = 887 Score = 49.7 bits (117), Expect = 3e-05 Identities = 92/473 (19%), Positives = 170/473 (35%), Gaps = 53/473 (11%) Query: 1716 KTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVK---SAQQEASADVATPKMPGQSV 1772 K +E S ++D + Q Q+ N K S ++ + +PK + Sbjct: 218 KETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKL 277 Query: 1773 RK-----KTRKAKEISEASENIYSDVRGLSQNQQIPQNSV-------TPRRGRRKKEVNQ 1820 ++ K + + +S + I SD L + P + V T +G R E Sbjct: 278 KEISLACKITELESVSLPTPEIQSDF--LHSKVEAPPSEVADTLVIMTASKGVRLPEPKD 335 Query: 1821 DILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVE 1880 ILE + ++ + T E K+ S++ EP K ++ + TP K +++ Sbjct: 336 KILETPQKMTEKSESKTPGEGKKEDKSRMAEPM-----KGYMRPTKSRGLTPLLPKSTIQ 390 Query: 1881 NQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRG 1940 QE + LK + + P + T D + NK+ S +K+ + + Sbjct: 391 EQERHK---QLKSAGIARPEEGRPVVSGTGNDIT-TPPNKELPPSPEKKTKPLATTQPAK 446 Query: 1941 REVSPSDVREDS-----------NLESSQLTVQAEFDMSAIPRK----RGRPRKINPSED 1985 S + + S L +++ + +A P++ RP I PS+D Sbjct: 447 TSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARP-SILPSKD 505 Query: 1986 VGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILV--PNEELSMVMS 2043 V K + + ++P+K+ +PS + + V K ++ P+ + Sbjct: 506 VKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLL 565 Query: 2044 SKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSK 2103 KK KTE + + + D K T+ + T S T + K Sbjct: 566 PKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK 625 Query: 2104 AILLPDLSEPNNEPLF-------SPASEVPRKAKAKKIEVPAQLKELVSDLSS 2149 A +P S P+ P P+S PR ++ LK + S + S Sbjct: 626 ATPMP--SRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGS 676 >gi|104526627 triadin [Homo sapiens] Length = 729 Score = 49.7 bits (117), Expect = 3e-05 Identities = 103/511 (20%), Positives = 182/511 (35%), Gaps = 117/511 (22%) Query: 1814 RKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPR 1873 RKKE+++D E E+++Q + K ++ E E+ KK + K+ Sbjct: 139 RKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREK--EKPEKKATHKEKIEKKEKP 196 Query: 1874 RIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIK 1933 K + Q+ K T +K E G KQ+ K ++K Sbjct: 197 ETKTLAKEQK--------KAKTAEKSEEKTKK---------EVKGGKQE-KVKQTAAKVK 238 Query: 1934 HVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPR--------------------- 1972 V++ +PS +E + E + ++ + D A R Sbjct: 239 EVQK------TPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPP 292 Query: 1973 -----KRGRPRKINPS--EDVGSKAVKEER---SPKKKEAPSIRRRSTRNTPAKSENVDV 2022 + RP +P+ E G K E++ KKKE I+++S + T +DV Sbjct: 293 PLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETA-----IDV 347 Query: 2023 GKPALGKSILVPNEELSMVMSS------KKKLTKKTESQSQKRSLHSVSEER-------- 2068 K GK+ + + + KK+ +KKT+ ++ +E+ Sbjct: 348 EKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPA 407 Query: 2069 ----------TDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPL 2118 +D+ +T +E + A + +++K + E + + Sbjct: 408 KSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTS 467 Query: 2119 FSPASEVPRKAKAKKIEVPAQLK---------ELVSDLSSQFVISPPALRSRQKNTSNKN 2169 + P K K +K VPA LK E +S + PP L+ ++ + Sbjct: 468 SILKDKEPIKGKEEK--VPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKK-----EE 520 Query: 2170 KLEDELKDDAQSV--ETLGKPKAKRIRTSKTKQASKNTEK----------ESAWSPPP-- 2215 K E ++K +A+ E + K ++ KT K EK E P P Sbjct: 521 KPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTK 580 Query: 2216 -IEIRLISPLASPADGVKSKPRKTTEVTGTG 2245 E R P + D K P+ T+EVT +G Sbjct: 581 KAEHREREPPSIKTDKPKPTPKGTSEVTESG 611 Score = 43.9 bits (102), Expect = 0.002 Identities = 77/397 (19%), Positives = 153/397 (38%), Gaps = 41/397 (10%) Query: 1636 GQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHE 1695 GQ +P + ++Q S+ P P A+ E + K K++TS+T ++ E Sbjct: 285 GQSPAIPPPLPTEQASR--------PTPASPALEEK--EGEKKKAEKKVTSETKKKE-KE 333 Query: 1696 TIPLVSQN---IMCPTKLVKSAFKTAQETSTMTMNVSQVDDVV---SSKTRTRGQRIQNV 1749 I S+ I K A +T Q T + + D S KT+ + Q Sbjct: 334 DIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPK 393 Query: 1750 NVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTP 1809 K ++E + A SV K++ +E ++ +S + +P Sbjct: 394 GKKQEKKEKHVEPAKSPKKEHSVPSD----KQVKAKTERAKEEIGAVSIKKAVPGKKEEK 449 Query: 1810 RRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTK 1869 ++E+ ++ TSS+ ++ + G+E K S + EP TKK+ K+S K Sbjct: 450 TTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEP----ETKKDEKMSKAGK 505 Query: 1870 RT---PRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDD--- 1923 P +++ E + +I + K S I K + + + G ++ Sbjct: 506 EVKPKPPQLQGKKEEKPEPQIKKEAK--PAISEKVQIHKQDIVKPEKTVSHGKPEEKVLK 563 Query: 1924 ----KSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRK 1979 + +K + K ++ RE P ++ D + T + +++ +K+ + Sbjct: 564 QVKAVTIEKTAKPKPTKKAEHREREPPSIKTD----KPKPTPKGTSEVTESGKKKTEISE 619 Query: 1980 INPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAK 2016 E K ++EE+ +KE+ + + PA+ Sbjct: 620 KESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPAR 656 >gi|117676384 splicing factor, arginine/serine-rich 2, interacting protein [Homo sapiens] Length = 1463 Score = 48.5 bits (114), Expect = 7e-05 Identities = 100/528 (18%), Positives = 197/528 (37%), Gaps = 90/528 (17%) Query: 1618 ANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPI--KVAIAENLLDV 1675 AN TEE++ G + + +LP V + + +K++ + + I+EN+L+ Sbjct: 462 ANYDTEERV---GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEK 518 Query: 1676 IKDTRSKEITSDTMEQSIHET-IPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQ-VDD 1733 D K+ + QS +T + V PT L + K Q S ++S+ V+ Sbjct: 519 GGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSES-KVYQPVSCPLSDLSENVES 577 Query: 1734 VVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPG------QSVRKKTRKAKEISEASE 1787 VV+ + T ++ K + + +PK+ Q+V +++ K+ E+ Sbjct: 578 VVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGH 637 Query: 1788 NIYSDVRGL----------------SQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVE- 1830 DV + S+N + N + + + +E N+ + E+ S E Sbjct: 638 VETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTEL 697 Query: 1831 -----QELQITTGRESKRLKSSQLLEPAVEETTKKEVKVS---SVTKRTPRRIKRSVENQ 1882 +++Q ++ + + + + + EV+ S + + + EN Sbjct: 698 PKTHIEQIQKHFSEDNNEMIPMEC-DSFCSDQNESEVEPSVNADLKQMNENSVTHCSENN 756 Query: 1883 ESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGRE 1942 + D KV TV+ PS + D + K R R R Sbjct: 757 MPSSDLADEKVETVSQPS----------------------ESPKDTIDKTKKPRTRRSRF 794 Query: 1943 VSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEA 2002 SPS + P+++ RP+ +P + G ++ K + K E+ Sbjct: 795 HSPSTTWSPNK---------------DTPQEKKRPQSPSPRRETGKESRKSQSPSPKNES 839 Query: 2003 PSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTE-SQSQKRSL 2061 R++S +P K D+ + P + + + L+ + E S+ KRS Sbjct: 840 ARGRKKSRSQSPKK----DIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQ 895 Query: 2062 HSVSEERTDEMTHKETNEQE--------ERLLATASFTKSSRSSRTRS 2101 V + E + ++ E+E ER T +++S SR+ S Sbjct: 896 PRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPS 943 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 47.8 bits (112), Expect = 1e-04 Identities = 60/323 (18%), Positives = 124/323 (38%), Gaps = 33/323 (10%) Query: 1950 EDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRS 2009 E S +E + + E +S K+ + + + V ++SP K AP ++ Sbjct: 465 EKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE 524 Query: 2010 TRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSE-ER 2068 + + + + KS ++ S K+ ++K E + ++ + +E E Sbjct: 525 GEKEEEEGQEEEEEEDEGAKS-----DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 579 Query: 2069 TDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRK 2128 + K+ E+ E + ++ + +K+ P P E SP + P + Sbjct: 580 AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKS---PVPKSPVEEKGKSPVPKSPVE 636 Query: 2129 AKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELK--------DDAQ 2180 K K VP K V + V P + + K+ +K+ +E++ K ++A+ Sbjct: 637 EKGKS-PVP---KSPVEEKGKSPVPKSP-VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 691 Query: 2181 SVETLGKPKAKRIRTSKTKQASKNTEKESAWSPP-----------PIEIRLISPLASPAD 2229 S +GK + K + K+A K + E P P++ ++ + + Sbjct: 692 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 751 Query: 2230 GVKSKPRKTTEVTGTGLGRNRKK 2252 VK K T+ G L + ++K Sbjct: 752 SVKVHLEKETKEEGKPLQQEKEK 774 Score = 42.0 bits (97), Expect = 0.007 Identities = 79/438 (18%), Positives = 153/438 (34%), Gaps = 54/438 (12%) Query: 1816 KEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEE----TTKKEVKVSSVTKRT 1871 ++ ++ E +++ +EL ++ E K + EP EE K VK ++ + Sbjct: 463 EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 522 Query: 1872 PRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLR 1931 K E QE E + D +E G++++ S ++ Sbjct: 523 EEGEKEEEEGQEEEE-----------------EEDEGAKSDQAEEGGSEKEGSSEKEEGE 565 Query: 1932 IKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSA-----IPRKRGRPRKINPSEDV 1986 + E ++ +E+ +E V + ++ A P K P +P E+ Sbjct: 566 QEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEK 625 Query: 1987 GSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKK 2046 G V + +K ++P KS + GK + KS P EE SK Sbjct: 626 GKSPVPKSPVEEKGKSP----------VPKSPVEEKGKSPVPKS---PVEEKGKSPVSKS 672 Query: 2047 KLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAIL 2106 + +K +S K + + E+ E E+EE+ + A + K Sbjct: 673 PVEEKAKSPVPKSPVEEAKSKA--EVGKGEQKEEEEKEVKEA---PKEEKVEKKEEKPKD 727 Query: 2107 LPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTS 2166 +P+ + + +EV K+ K+ + + KE L + + Sbjct: 728 VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEG 787 Query: 2167 NKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLAS 2226 + + K+D + G+ + K +TK+ E+E +++ S Sbjct: 788 SDKGAKGSRKED---IAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDL-------S 837 Query: 2227 PADGVKSKPRKTTEVTGT 2244 PAD K + +V T Sbjct: 838 PADEKKGGDKSEEKVVVT 855 Score = 40.8 bits (94), Expect = 0.015 Identities = 92/472 (19%), Positives = 167/472 (35%), Gaps = 97/472 (20%) Query: 1478 LNQEVALNLKEDHEVEVGVLKESVDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEA 1537 + +E+A+++KE+ + +E + EE++ SP V E+E + ++ G+E Sbjct: 476 ITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQE- 534 Query: 1538 RNLSFNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILE 1597 +++ D D AE +E +G E Sbjct: 535 -----------------------EEEEEDEGAKSDQAEEGGSEKEGS-----------SE 560 Query: 1598 GEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTL 1657 EEGE E G+ + +A A EEK V + ++A V +D K +K Sbjct: 561 KEEGEQEEGETEAEAEGEEA--EAKEEKKV----EEKSEEVATKEELV-ADAKVEK---- 609 Query: 1658 PYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKT 1717 PE K + ++ +++ + +E+ +P Sbjct: 610 ---PEKAKSPVPKS---PVEEKGKSPVPKSPVEEKGKSPVPK----------------SP 647 Query: 1718 AQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTR 1777 +E + S V++ S V + E A PK P + + K Sbjct: 648 VEEKGKSPVPKSPVEEKGKSP------------VSKSPVEEKAKSPVPKSPVEEAKSKAE 695 Query: 1778 KAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILEN--------TSSV 1829 K E E +V+ + +++ + P+ KK+ + E T SV Sbjct: 696 VGK--GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSV 753 Query: 1830 EQELQITTGRESKRLKSSQLLEPAVEETTKKEV---KVSSVTKRTPRRIKRSVENQESVE 1886 + L+ T E K L+ + E A E +E K + +++ + VE +E VE Sbjct: 754 KVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE 813 Query: 1887 IINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRV 1938 K S ++ + LD S K DKS +K + K V ++ Sbjct: 814 QETKEKGSGREEEKGVV----TNGLDLSPADEKKGGDKSEEKVVVTKTVEKI 861 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 47.8 bits (112), Expect = 1e-04 Identities = 60/323 (18%), Positives = 124/323 (38%), Gaps = 33/323 (10%) Query: 1950 EDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRS 2009 E S +E + + E +S K+ + + + V ++SP K AP ++ Sbjct: 89 EKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE 148 Query: 2010 TRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSE-ER 2068 + + + + KS ++ S K+ ++K E + ++ + +E E Sbjct: 149 GEKEEEEGQEEEEEEDEGAKS-----DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 203 Query: 2069 TDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRK 2128 + K+ E+ E + ++ + +K+ P P E SP + P + Sbjct: 204 AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKS---PVPKSPVEEKGKSPVPKSPVE 260 Query: 2129 AKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELK--------DDAQ 2180 K K VP K V + V P + + K+ +K+ +E++ K ++A+ Sbjct: 261 EKGKS-PVP---KSPVEEKGKSPVPKSP-VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 315 Query: 2181 SVETLGKPKAKRIRTSKTKQASKNTEKESAWSPP-----------PIEIRLISPLASPAD 2229 S +GK + K + K+A K + E P P++ ++ + + Sbjct: 316 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 375 Query: 2230 GVKSKPRKTTEVTGTGLGRNRKK 2252 VK K T+ G L + ++K Sbjct: 376 SVKVHLEKETKEEGKPLQQEKEK 398 Score = 42.0 bits (97), Expect = 0.007 Identities = 79/438 (18%), Positives = 153/438 (34%), Gaps = 54/438 (12%) Query: 1816 KEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEE----TTKKEVKVSSVTKRT 1871 ++ ++ E +++ +EL ++ E K + EP EE K VK ++ + Sbjct: 87 EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 146 Query: 1872 PRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLR 1931 K E QE E + D +E G++++ S ++ Sbjct: 147 EEGEKEEEEGQEEEE-----------------EEDEGAKSDQAEEGGSEKEGSSEKEEGE 189 Query: 1932 IKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSA-----IPRKRGRPRKINPSEDV 1986 + E ++ +E+ +E V + ++ A P K P +P E+ Sbjct: 190 QEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEK 249 Query: 1987 GSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKK 2046 G V + +K ++P KS + GK + KS P EE SK Sbjct: 250 GKSPVPKSPVEEKGKSP----------VPKSPVEEKGKSPVPKS---PVEEKGKSPVSKS 296 Query: 2047 KLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAIL 2106 + +K +S K + + E+ E E+EE+ + A + K Sbjct: 297 PVEEKAKSPVPKSPVEEAKSKA--EVGKGEQKEEEEKEVKEA---PKEEKVEKKEEKPKD 351 Query: 2107 LPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTS 2166 +P+ + + +EV K+ K+ + + KE L + + Sbjct: 352 VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEG 411 Query: 2167 NKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLAS 2226 + + K+D + G+ + K +TK+ E+E +++ S Sbjct: 412 SDKGAKGSRKED---IAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDL-------S 461 Query: 2227 PADGVKSKPRKTTEVTGT 2244 PAD K + +V T Sbjct: 462 PADEKKGGDKSEEKVVVT 479 Score = 40.8 bits (94), Expect = 0.015 Identities = 92/472 (19%), Positives = 167/472 (35%), Gaps = 97/472 (20%) Query: 1478 LNQEVALNLKEDHEVEVGVLKESVDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEA 1537 + +E+A+++KE+ + +E + EE++ SP V E+E + ++ G+E Sbjct: 100 ITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQE- 158 Query: 1538 RNLSFNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILE 1597 +++ D D AE +E +G E Sbjct: 159 -----------------------EEEEEDEGAKSDQAEEGGSEKEGS-----------SE 184 Query: 1598 GEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTL 1657 EEGE E G+ + +A A EEK V + ++A V +D K +K Sbjct: 185 KEEGEQEEGETEAEAEGEEA--EAKEEKKV----EEKSEEVATKEELV-ADAKVEK---- 233 Query: 1658 PYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKT 1717 PE K + ++ +++ + +E+ +P Sbjct: 234 ---PEKAKSPVPKS---PVEEKGKSPVPKSPVEEKGKSPVPK----------------SP 271 Query: 1718 AQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTR 1777 +E + S V++ S V + E A PK P + + K Sbjct: 272 VEEKGKSPVPKSPVEEKGKSP------------VSKSPVEEKAKSPVPKSPVEEAKSKAE 319 Query: 1778 KAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILEN--------TSSV 1829 K E E +V+ + +++ + P+ KK+ + E T SV Sbjct: 320 VGK--GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSV 377 Query: 1830 EQELQITTGRESKRLKSSQLLEPAVEETTKKEV---KVSSVTKRTPRRIKRSVENQESVE 1886 + L+ T E K L+ + E A E +E K + +++ + VE +E VE Sbjct: 378 KVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE 437 Query: 1887 IINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRV 1938 K S ++ + LD S K DKS +K + K V ++ Sbjct: 438 QETKEKGSGREEEKGVV----TNGLDLSPADEKKGGDKSEEKVVVTKTVEKI 485 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 47.8 bits (112), Expect = 1e-04 Identities = 130/759 (17%), Positives = 299/759 (39%), Gaps = 73/759 (9%) Query: 1473 VSERRLNQEVALNLKEDHEVEVGVLKESVDLPEEKLPISDSPPDTQEIHVIEQEKLEAQD 1532 + E + QE +LN+KE ++ E E+ DS EI ++ K Q+ Sbjct: 1379 IQESQSKQEQSLNMKEKDNETTKIVSEM-----EQFKPKDSALLRIEIEMLGLSK-RLQE 1432 Query: 1533 SGEEARNLS--------FNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAEVDGE 1584 S +E ++++ E+ S + +L+ N I + + + A C + E + Sbjct: 1433 SHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEET 1492 Query: 1585 LFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSA 1644 + + N + E E ++ A +D L E++ E N QI+ + Sbjct: 1493 INELRVNLSE-KETEISTIQKQLEAINDKLQNKIQEIYEKE-----EQFNIKQISEVQEK 1546 Query: 1645 VTS-----DQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPL 1699 V + + K L + K+ N L ++ I + + E + + Sbjct: 1547 VNELKQFKEHRKAKDSALQSIES--KMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQI 1604 Query: 1700 VSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQR----IQNVNVKSAQ 1755 + TK + + K +QE + ++ V++ + Q +N+++ + Sbjct: 1605 ERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIE 1664 Query: 1756 QEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRK 1815 E + +R T++ ++ E + + L +N + T R K Sbjct: 1665 TENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLR-----ETITRDLEK 1719 Query: 1816 KE----VNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRT 1871 +E V+ + E+ ++++ I + + ++ + LE + + +++K+ + Sbjct: 1720 QEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIA 1779 Query: 1872 PRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTN---------LDASEN---TGN 1919 +K E QE+++ + + S M + L ++N L A+E+ T Sbjct: 1780 HMHLK---EQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLK 1836 Query: 1920 KQDDKSSDKQLRIKHVRR-VRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPR 1978 K +++ K ++ +++ ++ + ++ S + E NL +Q + +M ++ ++R R Sbjct: 1837 KDVNETQKKVSEMEQLKKQIKDQSLTLSKL-EIENLNLAQKLHENLEEMKSVMKERDNLR 1895 Query: 1979 KINPSEDVGSKAVKEERSPKKKEAPSIRRR-STRNTPAKS--ENVDVGKPALGKSILVPN 2035 ++ + + +KE K I++ T +K E VD + + + + + Sbjct: 1896 RVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQIS 1955 Query: 2036 EELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSR 2095 + + SK +L KK + + QK+ L + + M+HK+ NE E+ K Sbjct: 1956 DIQKDLDKSKDELQKKIQ-ELQKKELQLLRVKEDVNMSHKKINEMEQ--------LKKQF 2006 Query: 2096 SSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISP 2155 ++ S +++ + + + L E+ + AK+ + ++KE + QF+ + Sbjct: 2007 EAQNLSMQSVRMDNFQ--LTKKLHESLEEI--RIVAKERDELRRIKESLKMERDQFIATL 2062 Query: 2156 PALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIR 2194 + +R + + L D Q + + K RI+ Sbjct: 2063 REMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIK 2101 Score = 41.6 bits (96), Expect = 0.009 Identities = 129/712 (18%), Positives = 283/712 (39%), Gaps = 83/712 (11%) Query: 1290 EMDEGSQSLEKLDVSKG--NSSVS------ITSDETTLEYQ-DAPSPEDLEETVFTASKP 1340 E D+ +Q LE+ D+ + N + +TS TL+ + A + + +K Sbjct: 372 EKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKM 431 Query: 1341 KSSSTA----LTTNVTEQTEK-------DGDKDVFASEVTPSDLQKQMGNLEDAETKDLL 1389 K+S+ A + TN+T +T K + D+ V + S+ + +E LL Sbjct: 432 KNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLL 491 Query: 1390 VAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVETYTPAIRAND 1449 SELN L + +L YE ++ T+K ++ + + ++ + R Sbjct: 492 NQENIESELNSL---RADYDNLVLD--YE-QLRTEKEEMELKLKEKNDLDEFEALERKTK 545 Query: 1450 NKSMADVLGDGGNSSLTISEGPIVSERRLNQ-EVALNLKEDHEVEVGVLKESVD---LPE 1505 ++ + N + + ++ N+ + L + E ++ L+E +D L Sbjct: 546 KDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLEN 605 Query: 1506 EKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTIDQQFC 1565 K+ +S S ++ ++Q +A+ +A+ S S L+L+ + + Sbjct: 606 IKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRES--AFLRSENLELKEKMKELATTYK 663 Query: 1566 DLADNKDTAECDI-------AEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDV----- 1613 + ++ + + +++ EL A + T + +G+V + ++ Sbjct: 664 QMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKIT 723 Query: 1614 -LPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENL 1672 L K N EE E ++ +LPS V +K + + E + + +E Sbjct: 724 DLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKS-----EELHIITSE-- 776 Query: 1673 LDVIKDTRSKEIT-SDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQV 1731 KD E+ ++ Q + E I ++ KS + Q T+ M+ Q Sbjct: 777 ----KDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQK 832 Query: 1732 DDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMP--GQSVRKKTRKAKEISEASENI 1789 +V + Q I N++ ++ + ++S ++ Q +++KTR+ +E E + Sbjct: 833 YKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQL 892 Query: 1790 YSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQL 1849 + +N+ +V + +++ Q + E + +++ + +ES +++ QL Sbjct: 893 KEQL----ENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQL 948 Query: 1850 LEPAVEETTKKEVKVSSVTKRTPRRIKRSVEN-QESVEIINDLKVSTVTSPSRMIRKLRS 1908 + + +T + T +++ ++E+ ++ E IN LK SR Sbjct: 949 -KSDIHDTVNMNID-------TQEQLRNALESLKQHQETINTLKSKISEEVSR------- 993 Query: 1909 TNLDASENTGNKQDDKSSDKQLRI--KHVRRVRGREVSPSDVREDSNLESSQ 1958 NL ENTG +D+ K + I K + + +DV+++ +E + Sbjct: 994 -NLHMEENTGETKDE-FQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQR 1043 >gi|41322923 plectin 1 isoform 11 [Homo sapiens] Length = 4547 Score = 47.8 bits (112), Expect = 1e-04 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%) Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765 +K A KTAQ ++ Q + V ++ R +R Q + A++EA ++ Sbjct: 1580 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1634 Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812 ++ + +A+E+++ ++ RG ++ Q + Q + + Sbjct: 1635 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1694 Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872 +++++ + + + EQEL + + QLLE EE + + + ++ T+ Sbjct: 1695 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1748 Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928 KR E ++ +++V + S +R + RST+ + + G ++ Sbjct: 1749 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804 Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975 +LR R R+++ D R+ + E+++L +AE + + Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1864 Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031 R R++ E + ++E+ + K + I R + A ++ K L + Sbjct: 1865 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1921 Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091 V E L++ S +K K E + + + S +E+ E +R LA A Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1980 Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150 + R + R K++ + + + A E + KA K+E +L+E S+ Q Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2035 Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200 ++ A + R + + + E EL+ Q +++ G+ +A R + ++ Sbjct: 2036 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2095 Query: 2201 ASKNTEKESAWSPPPIE 2217 A E+E+A S +E Sbjct: 2096 ARVQAEREAAQSRRQVE 2112 >gi|41322914 plectin 1 isoform 10 [Homo sapiens] Length = 4551 Score = 47.8 bits (112), Expect = 1e-04 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%) Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765 +K A KTAQ ++ Q + V ++ R +R Q + A++EA ++ Sbjct: 1584 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1638 Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812 ++ + +A+E+++ ++ RG ++ Q + Q + + Sbjct: 1639 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1698 Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872 +++++ + + + EQEL + + QLLE EE + + + ++ T+ Sbjct: 1699 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1752 Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928 KR E ++ +++V + S +R + RST+ + + G ++ Sbjct: 1753 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1808 Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975 +LR R R+++ D R+ + E+++L +AE + + Sbjct: 1809 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1868 Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031 R R++ E + ++E+ + K + I R + A ++ K L + Sbjct: 1869 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1925 Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091 V E L++ S +K K E + + + S +E+ E +R LA A Sbjct: 1926 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1984 Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150 + R + R K++ + + + A E + KA K+E +L+E S+ Q Sbjct: 1985 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2039 Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200 ++ A + R + + + E EL+ Q +++ G+ +A R + ++ Sbjct: 2040 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2099 Query: 2201 ASKNTEKESAWSPPPIE 2217 A E+E+A S +E Sbjct: 2100 ARVQAEREAAQSRRQVE 2116 >gi|41322919 plectin 1 isoform 8 [Homo sapiens] Length = 4547 Score = 47.8 bits (112), Expect = 1e-04 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%) Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765 +K A KTAQ ++ Q + V ++ R +R Q + A++EA ++ Sbjct: 1580 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1634 Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812 ++ + +A+E+++ ++ RG ++ Q + Q + + Sbjct: 1635 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1694 Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872 +++++ + + + EQEL + + QLLE EE + + + ++ T+ Sbjct: 1695 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1748 Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928 KR E ++ +++V + S +R + RST+ + + G ++ Sbjct: 1749 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804 Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975 +LR R R+++ D R+ + E+++L +AE + + Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1864 Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031 R R++ E + ++E+ + K + I R + A ++ K L + Sbjct: 1865 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1921 Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091 V E L++ S +K K E + + + S +E+ E +R LA A Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1980 Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150 + R + R K++ + + + A E + KA K+E +L+E S+ Q Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2035 Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200 ++ A + R + + + E EL+ Q +++ G+ +A R + ++ Sbjct: 2036 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2095 Query: 2201 ASKNTEKESAWSPPPIE 2217 A E+E+A S +E Sbjct: 2096 ARVQAEREAAQSRRQVE 2112 >gi|41322910 plectin 1 isoform 7 [Homo sapiens] Length = 4515 Score = 47.8 bits (112), Expect = 1e-04 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%) Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765 +K A KTAQ ++ Q + V ++ R +R Q + A++EA ++ Sbjct: 1548 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1602 Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812 ++ + +A+E+++ ++ RG ++ Q + Q + + Sbjct: 1603 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1662 Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872 +++++ + + + EQEL + + QLLE EE + + + ++ T+ Sbjct: 1663 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1716 Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928 KR E ++ +++V + S +R + RST+ + + G ++ Sbjct: 1717 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1772 Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975 +LR R R+++ D R+ + E+++L +AE + + Sbjct: 1773 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1832 Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031 R R++ E + ++E+ + K + I R + A ++ K L + Sbjct: 1833 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1889 Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091 V E L++ S +K K E + + + S +E+ E +R LA A Sbjct: 1890 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1948 Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150 + R + R K++ + + + A E + KA K+E +L+E S+ Q Sbjct: 1949 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2003 Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200 ++ A + R + + + E EL+ Q +++ G+ +A R + ++ Sbjct: 2004 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2063 Query: 2201 ASKNTEKESAWSPPPIE 2217 A E+E+A S +E Sbjct: 2064 ARVQAEREAAQSRRQVE 2080 >gi|41322916 plectin 1 isoform 6 [Homo sapiens] Length = 4684 Score = 47.8 bits (112), Expect = 1e-04 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%) Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765 +K A KTAQ ++ Q + V ++ R +R Q + A++EA ++ Sbjct: 1717 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1771 Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812 ++ + +A+E+++ ++ RG ++ Q + Q + + Sbjct: 1772 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1831 Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872 +++++ + + + EQEL + + QLLE EE + + + ++ T+ Sbjct: 1832 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1885 Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928 KR E ++ +++V + S +R + RST+ + + G ++ Sbjct: 1886 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1941 Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975 +LR R R+++ D R+ + E+++L +AE + + Sbjct: 1942 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 2001 Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031 R R++ E + ++E+ + K + I R + A ++ K L + Sbjct: 2002 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 2058 Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091 V E L++ S +K K E + + + S +E+ E +R LA A Sbjct: 2059 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 2117 Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150 + R + R K++ + + + A E + KA K+E +L+E S+ Q Sbjct: 2118 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2172 Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200 ++ A + R + + + E EL+ Q +++ G+ +A R + ++ Sbjct: 2173 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2232 Query: 2201 ASKNTEKESAWSPPPIE 2217 A E+E+A S +E Sbjct: 2233 ARVQAEREAAQSRRQVE 2249 >gi|41322908 plectin 1 isoform 3 [Homo sapiens] Length = 4525 Score = 47.8 bits (112), Expect = 1e-04 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%) Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765 +K A KTAQ ++ Q + V ++ R +R Q + A++EA ++ Sbjct: 1558 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1612 Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812 ++ + +A+E+++ ++ RG ++ Q + Q + + Sbjct: 1613 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1672 Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872 +++++ + + + EQEL + + QLLE EE + + + ++ T+ Sbjct: 1673 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1726 Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928 KR E ++ +++V + S +R + RST+ + + G ++ Sbjct: 1727 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1782 Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975 +LR R R+++ D R+ + E+++L +AE + + Sbjct: 1783 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1842 Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031 R R++ E + ++E+ + K + I R + A ++ K L + Sbjct: 1843 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1899 Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091 V E L++ S +K K E + + + S +E+ E +R LA A Sbjct: 1900 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1958 Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150 + R + R K++ + + + A E + KA K+E +L+E S+ Q Sbjct: 1959 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2013 Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200 ++ A + R + + + E EL+ Q +++ G+ +A R + ++ Sbjct: 2014 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2073 Query: 2201 ASKNTEKESAWSPPPIE 2217 A E+E+A S +E Sbjct: 2074 ARVQAEREAAQSRRQVE 2090 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.129 0.365 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 85,043,960 Number of Sequences: 37866 Number of extensions: 3977677 Number of successful extensions: 13545 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 578 Number of HSP's that attempted gapping in prelim test: 12082 Number of HSP's gapped (non-prelim): 2028 length of query: 2266 length of database: 18,247,518 effective HSP length: 118 effective length of query: 2148 effective length of database: 13,779,330 effective search space: 29598000840 effective search space used: 29598000840 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.