Guide to the Human Genome
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Search of human proteins with 67551265

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|67551265 transcription factor ELYS [Homo sapiens]
         (2266 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|67551265 transcription factor ELYS [Homo sapiens]                 4457   0.0  
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    62   5e-09
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    62   5e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     62   8e-09
gi|87299628 biorientation of chromosomes in cell division 1-like...    61   1e-08
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]    59   5e-08
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    56   5e-07
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    55   6e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    52   5e-06
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          52   5e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    52   9e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         50   2e-05
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  50   3e-05
gi|118421089 chromodomain helicase DNA binding protein 2 isoform...    50   3e-05
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]     50   3e-05
gi|110611184 chromodomain helicase DNA binding protein 2 isoform...    50   3e-05
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po...    50   3e-05
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa...    50   3e-05
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap...    50   3e-05
gi|104526627 triadin [Homo sapiens]                                    50   3e-05
gi|117676384 splicing factor, arginine/serine-rich 2, interactin...    49   7e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    48   1e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    48   1e-04
gi|71061468 centromere protein E [Homo sapiens]                        48   1e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        48   1e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        48   1e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         48   1e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         48   1e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         48   1e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         48   1e-04

>gi|67551265 transcription factor ELYS [Homo sapiens]
          Length = 2266

 Score = 4457 bits (11559), Expect = 0.0
 Identities = 2266/2266 (100%), Positives = 2266/2266 (100%)

Query: 1    MRDLRAQVTSGLLPFPEVTLQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSI 60
            MRDLRAQVTSGLLPFPEVTLQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSI
Sbjct: 1    MRDLRAQVTSGLLPFPEVTLQALGEDEITLESVLRGKFAAGKNGLACLACGPQLEVVNSI 60

Query: 61   TGERLSAYRFSGVNEQPPVVLAVKEFSWQKRTGLLIGLEETEGSVLCLYDLGISKVVKAV 120
            TGERLSAYRFSGVNEQPPVVLAVKEFSWQKRTGLLIGLEETEGSVLCLYDLGISKVVKAV
Sbjct: 61   TGERLSAYRFSGVNEQPPVVLAVKEFSWQKRTGLLIGLEETEGSVLCLYDLGISKVVKAV 120

Query: 121  VLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLVDLCLDDLSCNQN 180
            VLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLVDLCLDDLSCNQN
Sbjct: 121  VLPGRVTAIEPIINHGGASASTQHLHPSLRWLFGVAAVVTDVGQILLVDLCLDDLSCNQN 180

Query: 181  EVEASDLEVLTGIPAEVPHIRESVMRQGRHLCFQLVSPTGTAVSTLSYISRTNQLAVGFS 240
            EVEASDLEVLTGIPAEVPHIRESVMRQGRHLCFQLVSPTGTAVSTLSYISRTNQLAVGFS
Sbjct: 181  EVEASDLEVLTGIPAEVPHIRESVMRQGRHLCFQLVSPTGTAVSTLSYISRTNQLAVGFS 240

Query: 241  DGYLALWNMKSMKREYYIQLESGQVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLS 300
            DGYLALWNMKSMKREYYIQLESGQVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLS
Sbjct: 241  DGYLALWNMKSMKREYYIQLESGQVPVYAVTFQEPENDPRNCCYLWAVQSTQDSEGDVLS 300

Query: 301  LHLLQLAFGNRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTSNTKLLGCQSIEKF 360
            LHLLQLAFGNRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTSNTKLLGCQSIEKF
Sbjct: 301  LHLLQLAFGNRKCLASGQILYEGLEYCEERYTLDLTGGMFPLRGQTSNTKLLGCQSIEKF 360

Query: 361  RSHGDREEGVNEALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGE 420
            RSHGDREEGVNEALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGE
Sbjct: 361  RSHGDREEGVNEALSPDTSVSVFTWQVNIYGQGKPSVYLGLFDINRWYHAQMPDSLRSGE 420

Query: 421  YLHNCSYFALWSLESVVSRTSPHGILDILVHERSLNRGVPPSYPPPEQFFNPSTYNFDAT 480
            YLHNCSYFALWSLESVVSRTSPHGILDILVHERSLNRGVPPSYPPPEQFFNPSTYNFDAT
Sbjct: 421  YLHNCSYFALWSLESVVSRTSPHGILDILVHERSLNRGVPPSYPPPEQFFNPSTYNFDAT 480

Query: 481  CLLNSGVVHLTCTGFQKETLTFLKKSGPSLNELIPDGYNRCLVAGLLSPRFVDVQPSSLS 540
            CLLNSGVVHLTCTGFQKETLTFLKKSGPSLNELIPDGYNRCLVAGLLSPRFVDVQPSSLS
Sbjct: 481  CLLNSGVVHLTCTGFQKETLTFLKKSGPSLNELIPDGYNRCLVAGLLSPRFVDVQPSSLS 540

Query: 541  QEEQLEAILSAAIQTSSLGLLTGYIRRWITEEQPNSATNLRFVLEWTWNKVVLTKEEFDR 600
            QEEQLEAILSAAIQTSSLGLLTGYIRRWITEEQPNSATNLRFVLEWTWNKVVLTKEEFDR
Sbjct: 541  QEEQLEAILSAAIQTSSLGLLTGYIRRWITEEQPNSATNLRFVLEWTWNKVVLTKEEFDR 600

Query: 601  LCVPLFDGSCHFMDPQTIQSIQQCYLLLSNLNIVLSCFASEAREITERGLIDLSNKFVVS 660
            LCVPLFDGSCHFMDPQTIQSIQQCYLLLSNLNIVLSCFASEAREITERGLIDLSNKFVVS
Sbjct: 601  LCVPLFDGSCHFMDPQTIQSIQQCYLLLSNLNIVLSCFASEAREITERGLIDLSNKFVVS 660

Query: 661  HLICQYAQVVLWFSHSGLLPEGIDDSVQLSRLCYNYPVIQNYYTSRRQKFERLSRGKWNP 720
            HLICQYAQVVLWFSHSGLLPEGIDDSVQLSRLCYNYPVIQNYYTSRRQKFERLSRGKWNP
Sbjct: 661  HLICQYAQVVLWFSHSGLLPEGIDDSVQLSRLCYNYPVIQNYYTSRRQKFERLSRGKWNP 720

Query: 721  DCLMIDGLVSQLGERIEKLWKRDEGGTGKYPPASLHAVLDMYLLDGVTEAAKHSITIYLL 780
            DCLMIDGLVSQLGERIEKLWKRDEGGTGKYPPASLHAVLDMYLLDGVTEAAKHSITIYLL
Sbjct: 721  DCLMIDGLVSQLGERIEKLWKRDEGGTGKYPPASLHAVLDMYLLDGVTEAAKHSITIYLL 780

Query: 781  LDIMYSFPNKTDTPIESFPTVFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPLS 840
            LDIMYSFPNKTDTPIESFPTVFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPLS
Sbjct: 781  LDIMYSFPNKTDTPIESFPTVFAISWGQVKLIQGFWLIDHNDYESGLDLLFHPATAKPLS 840

Query: 841  WQHSKIIQAFMSQGEHRQALRYIQTMKPTVSSGNDVILHLTVLLFNRCMVEAWNFLRQHC 900
            WQHSKIIQAFMSQGEHRQALRYIQTMKPTVSSGNDVILHLTVLLFNRCMVEAWNFLRQHC
Sbjct: 841  WQHSKIIQAFMSQGEHRQALRYIQTMKPTVSSGNDVILHLTVLLFNRCMVEAWNFLRQHC 900

Query: 901  NRLNIEELLKHMYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQ 960
            NRLNIEELLKHMYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQ
Sbjct: 901  NRLNIEELLKHMYEVCQEMGLMEDLLKLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQ 960

Query: 961  RANYVPALKLNQTLKINVMNDRDPRLRERSLARNSILDQYGKILPRVHRKLAIERAKPYH 1020
            RANYVPALKLNQTLKINVMNDRDPRLRERSLARNSILDQYGKILPRVHRKLAIERAKPYH
Sbjct: 961  RANYVPALKLNQTLKINVMNDRDPRLRERSLARNSILDQYGKILPRVHRKLAIERAKPYH 1020

Query: 1021 LSTSSVFRLVSRPKPLSAVPKQVVTGTVLTRSVFINNVLSKIGEVWASKEPINSTTPFNS 1080
            LSTSSVFRLVSRPKPLSAVPKQVVTGTVLTRSVFINNVLSKIGEVWASKEPINSTTPFNS
Sbjct: 1021 LSTSSVFRLVSRPKPLSAVPKQVVTGTVLTRSVFINNVLSKIGEVWASKEPINSTTPFNS 1080

Query: 1081 SKIEEPSPIVYSLPAPELPEAFFGTPISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSM 1140
            SKIEEPSPIVYSLPAPELPEAFFGTPISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSM
Sbjct: 1081 SKIEEPSPIVYSLPAPELPEAFFGTPISKASQKISRLLDLVVQPVPRPSQCSEFIQQSSM 1140

Query: 1141 KSPLYLVSRSLPSSSQLKGSPQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQ 1200
            KSPLYLVSRSLPSSSQLKGSPQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQ
Sbjct: 1141 KSPLYLVSRSLPSSSQLKGSPQAISRASELHLLETPLVVKKAKSLAMSVTTSGFSEFTPQ 1200

Query: 1201 SILRSTLRSTPLASPSPSPGRSPQRLKETRISFVEEDVHPKWIPGAADDSKLEVFTTPKK 1260
            SILRSTLRSTPLASPSPSPGRSPQRLKETRISFVEEDVHPKWIPGAADDSKLEVFTTPKK
Sbjct: 1201 SILRSTLRSTPLASPSPSPGRSPQRLKETRISFVEEDVHPKWIPGAADDSKLEVFTTPKK 1260

Query: 1261 CAVPVETEWLKSKDRTTSFFLNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLE 1320
            CAVPVETEWLKSKDRTTSFFLNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLE
Sbjct: 1261 CAVPVETEWLKSKDRTTSFFLNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLE 1320

Query: 1321 YQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNL 1380
            YQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNL
Sbjct: 1321 YQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNL 1380

Query: 1381 EDAETKDLLVAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVET 1440
            EDAETKDLLVAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVET
Sbjct: 1381 EDAETKDLLVAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVET 1440

Query: 1441 YTPAIRANDNKSMADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKES 1500
            YTPAIRANDNKSMADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKES
Sbjct: 1441 YTPAIRANDNKSMADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKES 1500

Query: 1501 VDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTI 1560
            VDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTI
Sbjct: 1501 VDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTI 1560

Query: 1561 DQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANT 1620
            DQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANT
Sbjct: 1561 DQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANT 1620

Query: 1621 ATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTR 1680
            ATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTR
Sbjct: 1621 ATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTR 1680

Query: 1681 SKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTR 1740
            SKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTR
Sbjct: 1681 SKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTR 1740

Query: 1741 TRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQ 1800
            TRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQ
Sbjct: 1741 TRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQ 1800

Query: 1801 QIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKK 1860
            QIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKK
Sbjct: 1801 QIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKK 1860

Query: 1861 EVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNK 1920
            EVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNK
Sbjct: 1861 EVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNK 1920

Query: 1921 QDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKI 1980
            QDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKI
Sbjct: 1921 QDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKI 1980

Query: 1981 NPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSM 2040
            NPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSM
Sbjct: 1981 NPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSM 2040

Query: 2041 VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR 2100
            VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR
Sbjct: 2041 VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR 2100

Query: 2101 SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS 2160
            SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS
Sbjct: 2101 SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS 2160

Query: 2161 RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRL 2220
            RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRL
Sbjct: 2161 RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRL 2220

Query: 2221 ISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRKML 2266
            ISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRKML
Sbjct: 2221 ISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRKML 2266


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 196/1053 (18%), Positives = 383/1053 (36%), Gaps = 189/1053 (17%)

Query: 1286 KEHQEMD----------EGSQSLEKLDVSKGNSSVSITSDETTLEYQDAPSPEDLEETVF 1335
            KEH+ +D          E   +LEK D+SK  + +S    ++   +Q+ P+ E       
Sbjct: 392  KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST 451

Query: 1336 TASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNLEDAETKDLLVAAEAF 1395
                 KS            T +D D D+ +    PS + + +   E+ ET     A E  
Sbjct: 452  GGEHKKSDRKEEPQYEPANTSEDLDMDIVS---VPSSVPEDI--FENLET-----AMEVQ 501

Query: 1396 SELNHLSP-VQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSV--ETY---TPAIRAND 1449
            S ++H      GTE  + + SV +  I ++ ++  +  +    V  E Y   TP   +N 
Sbjct: 502  SSVDHQGDGSSGTEQEVESSSV-KLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNS 560

Query: 1450 NKSMADV--LGDGGNSSLTISEGPIVSERRLNQEVALNLKEDH--EVEVGVLKESVDL-- 1503
                AD   +    +   +    P + +  L QE   N   +H  E EV +L E  DL  
Sbjct: 561  PIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQE---NSDNEHLVENEVSLLLEESDLRR 617

Query: 1504 -----------PEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLK 1552
                       P E  P++ +  +     V E++KL      ++ RN S + +      K
Sbjct: 618  SPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNK 677

Query: 1553 L--QYNFDTIDQ-----------QFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGE 1599
            L      +T+DQ           +      +  +++ DI E+           T   + +
Sbjct: 678  LPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDD 737

Query: 1600 EGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPY 1659
            +G+ +     S          + +  ++   +     + +N  S +  + KS        
Sbjct: 738  KGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMS------ 791

Query: 1660 VPEPIKVAIAENLLDVIKDTRSKEITSDT------MEQSIHETIPLVSQNIM--CPTKLV 1711
                 K+  A      I +T+  + + D       M+   H+ +    +        K  
Sbjct: 792  -----KIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE 846

Query: 1712 KSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKM---P 1768
            +  F +A+ T      + ++ D +  K +        V+  S ++++   +   K+    
Sbjct: 847  RETFSSAEGTVDKDTTIMELRDRLPKKQQASAS-TDGVDKLSGKEQSFTSLEVRKVAETK 905

Query: 1769 GQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQ-NSVTPRRGRRKKEVNQDILENTS 1827
             +S   KT+  K++ +   +I        Q+ +  + +    ++G  +K+   D  +   
Sbjct: 906  EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVI 965

Query: 1828 SVEQELQITTGRESKRLKSSQL------LEPAVEETTKKEVKVSSVTKRTPRR------- 1874
             +EQ+ + ++    K  +  ++      ++     TT  E K   +  +T ++       
Sbjct: 966  KMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDY 1025

Query: 1875 IKRSVENQESVEIINDLK-----VSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQ 1929
             ++S    +S +   D K             +++ K      D S +   K   K     
Sbjct: 1026 AEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCN 1085

Query: 1930 LRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSK 1989
               K ++R+        ++RE  NL S + T + +   S+   +         SED    
Sbjct: 1086 SSDKRLKRI--------ELRERRNLSSKRNTKEIQSGSSSSDAEES-------SED---N 1127

Query: 1990 AVKEERSPKKKEAPSI--RRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKK 2047
              K++R+  KK+A  +  ++R++  T  K +  D+                         
Sbjct: 1128 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI------------------------- 1162

Query: 2048 LTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILL 2107
             T  + S  +    +S+ E  +DE   K   E    L +   F +SS       S  + +
Sbjct: 1163 -TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLV-LSSHTGFCQSSGDEALSKSVPVTV 1220

Query: 2108 PDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSN 2167
             D  + N+          P    AKK+     L+E+ ++LSS            +  +S+
Sbjct: 1221 DDDDDDND----------PENRIAKKM----LLEEIKANLSSD-----------EDGSSD 1255

Query: 2168 KNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLASP 2227
                E + +   Q+ E  G  +AK    S++   S+ ++K      P    RL+    + 
Sbjct: 1256 DEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK------PRYRHRLLRHKLTV 1309

Query: 2228 ADG-----VKSKPRKTTEVTGTGLGRNRKKLSS 2255
            +DG      K+KP++  EV     GRNR+K+SS
Sbjct: 1310 SDGESGEEKKTKPKEHKEVK----GRNRRKVSS 1338



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 75/366 (20%), Positives = 137/366 (37%), Gaps = 62/366 (16%)

Query: 1774 KKTRKAKEISEASENIYSDVRG--LSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQ 1831
            K +RK ++ S +    YS       S ++++ +  +  RR    K   ++I   +SS + 
Sbjct: 1061 KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDA 1120

Query: 1832 ELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDL 1891
            E      ++ K+  SS+     V+E  +  ++ S  TKR    I  S  +   +E  +  
Sbjct: 1121 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTS--TKRKQADITSS--SSSDIEDDDQN 1176

Query: 1892 KVSTVTSPSRMIRKLRSTNLDASENTGNKQ-----------------DDKSSDKQLRIKH 1934
             +   +S  + I+ + + NL  S +TG  Q                 DD  +D + RI  
Sbjct: 1177 SIGEGSSDEQKIKPV-TENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1235

Query: 1935 ---VRRVRGREVSPSDVREDSNLES-------------------SQLTVQAEFDMSAIPR 1972
               +  ++    S  D   D   E                    +Q+  +++ D     +
Sbjct: 1236 KMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1295

Query: 1973 KRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAK-SENVDVGKPALGKSI 2031
             R R R +     V      EE+  K KE   ++ R+ R   ++ SE+ D  +  + + +
Sbjct: 1296 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1355

Query: 2032 LVPNEELSMVMSSKKK--LTKKTESQSQKRSLHSV-------------SEERTDEMTHKE 2076
                +E      S KK  L +   S  QK+    +             SEE  +E   +E
Sbjct: 1356 SESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE 1415

Query: 2077 TNEQEE 2082
              E+EE
Sbjct: 1416 EEEEEE 1421


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 196/1053 (18%), Positives = 383/1053 (36%), Gaps = 189/1053 (17%)

Query: 1286 KEHQEMD----------EGSQSLEKLDVSKGNSSVSITSDETTLEYQDAPSPEDLEETVF 1335
            KEH+ +D          E   +LEK D+SK  + +S    ++   +Q+ P+ E       
Sbjct: 430  KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST 489

Query: 1336 TASKPKSSSTALTTNVTEQTEKDGDKDVFASEVTPSDLQKQMGNLEDAETKDLLVAAEAF 1395
                 KS            T +D D D+ +    PS + + +   E+ ET     A E  
Sbjct: 490  GGEHKKSDRKEEPQYEPANTSEDLDMDIVS---VPSSVPEDI--FENLET-----AMEVQ 539

Query: 1396 SELNHLSP-VQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSV--ETY---TPAIRAND 1449
            S ++H      GTE  + + SV +  I ++ ++  +  +    V  E Y   TP   +N 
Sbjct: 540  SSVDHQGDGSSGTEQEVESSSV-KLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNS 598

Query: 1450 NKSMADV--LGDGGNSSLTISEGPIVSERRLNQEVALNLKEDH--EVEVGVLKESVDL-- 1503
                AD   +    +   +    P + +  L QE   N   +H  E EV +L E  DL  
Sbjct: 599  PIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQE---NSDNEHLVENEVSLLLEESDLRR 655

Query: 1504 -----------PEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLK 1552
                       P E  P++ +  +     V E++KL      ++ RN S + +      K
Sbjct: 656  SPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNK 715

Query: 1553 L--QYNFDTIDQ-----------QFCDLADNKDTAECDIAEVDGELFVAQSNFTLILEGE 1599
            L      +T+DQ           +      +  +++ DI E+           T   + +
Sbjct: 716  LPKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDD 775

Query: 1600 EGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPY 1659
            +G+ +     S          + +  ++   +     + +N  S +  + KS        
Sbjct: 776  KGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMS------ 829

Query: 1660 VPEPIKVAIAENLLDVIKDTRSKEITSDT------MEQSIHETIPLVSQNIM--CPTKLV 1711
                 K+  A      I +T+  + + D       M+   H+ +    +        K  
Sbjct: 830  -----KIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQE 884

Query: 1712 KSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKM---P 1768
            +  F +A+ T      + ++ D +  K +        V+  S ++++   +   K+    
Sbjct: 885  RETFSSAEGTVDKDTTIMELRDRLPKKQQASAS-TDGVDKLSGKEQSFTSLEVRKVAETK 943

Query: 1769 GQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQ-NSVTPRRGRRKKEVNQDILENTS 1827
             +S   KT+  K++ +   +I        Q+ +  + +    ++G  +K+   D  +   
Sbjct: 944  EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVI 1003

Query: 1828 SVEQELQITTGRESKRLKSSQL------LEPAVEETTKKEVKVSSVTKRTPRR------- 1874
             +EQ+ + ++    K  +  ++      ++     TT  E K   +  +T ++       
Sbjct: 1004 KMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDY 1063

Query: 1875 IKRSVENQESVEIINDLK-----VSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQ 1929
             ++S    +S +   D K             +++ K      D S +   K   K     
Sbjct: 1064 AEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCN 1123

Query: 1930 LRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSK 1989
               K ++R+        ++RE  NL S + T + +   S+   +         SED    
Sbjct: 1124 SSDKRLKRI--------ELRERRNLSSKRNTKEIQSGSSSSDAEES-------SED---N 1165

Query: 1990 AVKEERSPKKKEAPSI--RRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKK 2047
              K++R+  KK+A  +  ++R++  T  K +  D+                         
Sbjct: 1166 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI------------------------- 1200

Query: 2048 LTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILL 2107
             T  + S  +    +S+ E  +DE   K   E    L +   F +SS       S  + +
Sbjct: 1201 -TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLV-LSSHTGFCQSSGDEALSKSVPVTV 1258

Query: 2108 PDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSN 2167
             D  + N+          P    AKK+     L+E+ ++LSS            +  +S+
Sbjct: 1259 DDDDDDND----------PENRIAKKM----LLEEIKANLSSD-----------EDGSSD 1293

Query: 2168 KNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLASP 2227
                E + +   Q+ E  G  +AK    S++   S+ ++K      P    RL+    + 
Sbjct: 1294 DEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK------PRYRHRLLRHKLTV 1347

Query: 2228 ADG-----VKSKPRKTTEVTGTGLGRNRKKLSS 2255
            +DG      K+KP++  EV     GRNR+K+SS
Sbjct: 1348 SDGESGEEKKTKPKEHKEVK----GRNRRKVSS 1376



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 75/366 (20%), Positives = 137/366 (37%), Gaps = 62/366 (16%)

Query: 1774 KKTRKAKEISEASENIYSDVRG--LSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQ 1831
            K +RK ++ S +    YS       S ++++ +  +  RR    K   ++I   +SS + 
Sbjct: 1099 KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDA 1158

Query: 1832 ELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDL 1891
            E      ++ K+  SS+     V+E  +  ++ S  TKR    I  S  +   +E  +  
Sbjct: 1159 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTS--TKRKQADITSS--SSSDIEDDDQN 1214

Query: 1892 KVSTVTSPSRMIRKLRSTNLDASENTGNKQ-----------------DDKSSDKQLRIKH 1934
             +   +S  + I+ + + NL  S +TG  Q                 DD  +D + RI  
Sbjct: 1215 SIGEGSSDEQKIKPV-TENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAK 1273

Query: 1935 ---VRRVRGREVSPSDVREDSNLES-------------------SQLTVQAEFDMSAIPR 1972
               +  ++    S  D   D   E                    +Q+  +++ D     +
Sbjct: 1274 KMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKK 1333

Query: 1973 KRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAK-SENVDVGKPALGKSI 2031
             R R R +     V      EE+  K KE   ++ R+ R   ++ SE+ D  +  + + +
Sbjct: 1334 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEV 1393

Query: 2032 LVPNEELSMVMSSKKK--LTKKTESQSQKRSLHSV-------------SEERTDEMTHKE 2076
                +E      S KK  L +   S  QK+    +             SEE  +E   +E
Sbjct: 1394 SESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEE 1453

Query: 2077 TNEQEE 2082
              E+EE
Sbjct: 1454 EEEEEE 1459


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 61.6 bits (148), Expect = 8e-09
 Identities = 99/462 (21%), Positives = 175/462 (37%), Gaps = 45/462 (9%)

Query: 1765 PKMPGQSVRKKTRKAKEIS--EASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDI 1822
            PK+P  S   K +  ++I   E SE     V   ++  Q+ +          K+E  ++ 
Sbjct: 427  PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486

Query: 1823 L-----------ENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRT 1871
                        E T S   E   +  +E+K     +   PA  ++ +KE   S    ++
Sbjct: 487  EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546

Query: 1872 PRRIKRSV-ENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDK-Q 1929
            P + K    E  +S       +     SP+  ++        A E   +  + KS +K +
Sbjct: 547  PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAE-VKSPEKAKSPAKEEAKSPAEAKSPEKAK 605

Query: 1930 LRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSK 1989
              +K   +      SP  V+E++  +S       E   S    +   P K    E   +K
Sbjct: 606  SPVKEEAKSPAEAKSP--VKEEA--KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAK 661

Query: 1990 AVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLT 2049
            + ++ +SP K EA S  +  +   P K+E      P   KS +   EE       K K  
Sbjct: 662  SPEKAKSPVKAEAKSPEKAKS---PVKAE---AKSPEKAKSPV--KEEAKS--PEKAKSP 711

Query: 2050 KKTESQSQKRSLHSVSEE-RTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLP 2108
             K E++S +++   V EE +T E       E+ +    +    KS   ++T   K+   P
Sbjct: 712  VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK----SPEKAKSPEKAKTLDVKS---P 764

Query: 2109 DLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNK 2168
            +   P  E   SPA + P KAK+   E     ++  S L           ++ +K    K
Sbjct: 765  EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED-------AKAPEKEIPKK 817

Query: 2169 NKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESA 2210
             +++  +K++ +  E   K   K+    K     K  EK+ +
Sbjct: 818  EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDS 859



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 108/588 (18%), Positives = 203/588 (34%), Gaps = 73/588 (12%)

Query: 1598 GEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTL 1657
            GEE E E G+  +    P A   A+ EK   S   +     A  P+   S +K +     
Sbjct: 489  GEEEEAEGGEEETKS--PPAEEAASPEKEAKSPVKEE----AKSPAEAKSPEKEE----- 537

Query: 1658 PYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKL---VKSA 1714
                 P +V   E      K    +E  S    +S  +        +  P K     K  
Sbjct: 538  --AKSPAEVKSPEKA----KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 591

Query: 1715 FKTAQETSTMTMNVSQVDDVVSS----KTRTRGQRIQNVNVKSAQQEASADVATPKMPGQ 1770
             K+  E  +     S V +   S    K+  + +      VKS ++  S      K P +
Sbjct: 592  AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK 651

Query: 1771 SVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVE 1830
            +   +  +AK   +A   + ++ +        P+ + +P +   K           S V+
Sbjct: 652  AKSPEKEEAKSPEKAKSPVKAEAKS-------PEKAKSPVKAEAKSPEKAK-----SPVK 699

Query: 1831 QELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVT-KRTPRRIKRSVENQESVEIIN 1889
            +E      +  ++ KS    E    E  K  VK  + T ++    +K   ++ E  +   
Sbjct: 700  EE-----AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE 754

Query: 1890 DLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVR 1949
              K   V SP             A E   +  D      +  +K    V+  E + S ++
Sbjct: 755  KAKTLDVKSPE--------AKTPAKEEARSPADKFPEKAKSPVKE--EVKSPEKAKSPLK 804

Query: 1950 EDSNLESSQLTVQAEFDMSAIPRKRGR-------PRKINPSEDVGSKAVKEERSPKKKEA 2002
            ED+     ++  + E        ++ +       P+K    +   +   +E++  KK+EA
Sbjct: 805  EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA 864

Query: 2003 PSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTE--SQSQKRS 2060
            P       +    K   V+  K +  ++     E+   V + +K+   K E    ++ + 
Sbjct: 865  PKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE 924

Query: 2061 LHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFS 2120
               V+++  D+   KE ++  E+  A      +     T+  KA       +P  +P   
Sbjct: 925  KTEVAKKEPDDAKAKEPSKPAEKKEA------APEKKDTKEEKA------KKPEEKPKTE 972

Query: 2121 PASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNK 2168
              ++   K  +K+   P   K   S  + Q    PP   +  K    K
Sbjct: 973  AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020



 Score = 38.5 bits (88), Expect = 0.076
 Identities = 44/191 (23%), Positives = 76/191 (39%), Gaps = 20/191 (10%)

Query: 2057 QKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNE 2116
            +K +   V EE       K   ++E +  A     + ++S     +K+   P+   P  E
Sbjct: 513  EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP--PEAKSPEKE 570

Query: 2117 PLFSPAS-EVPRKAKA---KKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLE 2172
               SPA  + P KAK+   ++ + PA+ K       S      P     +     K+ ++
Sbjct: 571  EAKSPAEVKSPEKAKSPAKEEAKSPAEAK-------SPEKAKSPVKEEAKSPAEAKSPVK 623

Query: 2173 DELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWS------PPPIEIRLISPLAS 2226
            +E K  A+ V++  K K+     +K+ + +K+ EKE A S      P   E +      S
Sbjct: 624  EEAKSPAE-VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682

Query: 2227 PADGVKSKPRK 2237
            P       P K
Sbjct: 683  PVKAEAKSPEK 693



 Score = 33.1 bits (74), Expect = 3.2
 Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 2/80 (2%)

Query: 2154 SPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSP 2213
            SPPA  +       K+ +++E K  A++ ++  K +AK     K+ + +K+  KE A SP
Sbjct: 503  SPPAEEAASPEKEAKSPVKEEAKSPAEA-KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 561

Query: 2214 PPIEIRLISPLASPADGVKS 2233
            P  +        SPA+ VKS
Sbjct: 562  PEAKSPEKEEAKSPAE-VKS 580


>gi|87299628 biorientation of chromosomes in cell division 1-like
            [Homo sapiens]
          Length = 3051

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 127/613 (20%), Positives = 232/613 (37%), Gaps = 99/613 (16%)

Query: 1677 KDTRSKEITSDTMEQSI-----------HETIPLVSQNIMCPTKLVKSAFKTAQETSTMT 1725
            +DT  + +TSD+ME+             ++T    S +    TK V+ A+    +    +
Sbjct: 421  EDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAY--VHKPYLYS 478

Query: 1726 MNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEA 1785
               S  DD ++ +     QR Q++  +  ++     +   K+      ++ RK K     
Sbjct: 479  KYYSDSDDELTVE-----QRRQSIAKEKEERLLRRQINREKL------EEKRKQKAEKTK 527

Query: 1786 SENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLK 1845
            S       R     ++    S+ P+  R K     ++L+    +E+++ ++     KR K
Sbjct: 528  SSKTKGQGRSSVDLEESSTKSLEPKAARIK-----EVLKERKVLEKKVALS----KKRKK 578

Query: 1846 SSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLK-VSTVTSPSRMIR 1904
             S+     VEE +KK+ +    +K T +  +     +E +    +LK V   + PS+  R
Sbjct: 579  DSR----NVEENSKKKQQYEEDSKETLKTSEHC--EKEKISSSKELKHVHAKSEPSKPAR 632

Query: 1905 KLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAE 1964
            +L       SE+  +  D+  ++ +L  +H RR     V    V+E+++    +  V+  
Sbjct: 633  RL-------SESL-HVVDENKNESKLEREHKRRT-STPVIMEGVQEETDTRDVKRQVERS 683

Query: 1965 FDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK 2024
               +  P+K+    K               +S  KKE  S + +  R      + + V  
Sbjct: 684  EICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKH 743

Query: 2025 PALGKSILVPNEELSMVMSSKK-KLTKKTESQSQKRSLHS-------------------- 2063
               G  +    +E  +  S K  K+ +  + QSQ+  L S                    
Sbjct: 744  KYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLG 803

Query: 2064 -----VSEE--RTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNE 2116
                 VSE   +TDE   KE N++E RL  +A  TK+   SR  S   I    L    + 
Sbjct: 804  KDGKPVSEYIIKTDENVRKENNKKERRL--SAEKTKAEHKSRRSSDSKIQKDSLGSKQHG 861

Query: 2117 PLFSPASEVPRKAKA-----------KKIEVPAQLKELVSDLSSQFVISPPALRSRQKNT 2165
                  SE   + K            K  EV  + K     L  + ++    L+S+ K  
Sbjct: 862  ITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLV----LKSKSKTQ 917

Query: 2166 SNKNK-LEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPL 2224
              + K +E EL++ A    T  KP  ++     T++     +++S     P E   + P+
Sbjct: 918  GKQVKVVETELQEGATKQATTPKPDKEK----NTEENDSEKQRKSKVEDKPFEETGVEPV 973

Query: 2225 ASPADGVKSKPRK 2237
               A       +K
Sbjct: 974  LETASSSAHSTQK 986



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 100/455 (21%), Positives = 185/455 (40%), Gaps = 83/455 (18%)

Query: 1818 VNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKE---VKVSSVTKRTPRR 1874
            +NQ+     +S E     T+ R SK+L S    +P  + +T KE     ++   K T   
Sbjct: 211  LNQEASAARASTETSNAKTSERASKKLPS----QPTTDTSTDKERTSEDMADKEKSTADS 266

Query: 1875 IKRSVENQESVEIINDLK--VSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRI 1932
                +E     E  +DL   V  + + ++    L   N D  + + ++Q +KS+DK    
Sbjct: 267  GGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQES-SEQKNKSTDK---- 321

Query: 1933 KHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVK 1992
                   G +   S+ + +   E  + T + +FD S              SED  ++ VK
Sbjct: 322  -------GEKKPDSNEKGERKKEKKEKT-EKKFDHS------------KKSED--TQKVK 359

Query: 1993 EERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKT 2052
            +E+  K+KE  S++  S +N+  K++ V+  K           E+ S++ S    LT  T
Sbjct: 360  DEKQAKEKEVESLKLPSEKNS-NKAKTVEGTK-----------EDFSLIDSDVDGLTDIT 407

Query: 2053 ESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSE 2112
             S      L S  E+  +E+   ++ E+ E    T+   + ++ ++T++  +    D SE
Sbjct: 408  VSSVHTSDLSSFEEDTEEEVVTSDSMEEGE---ITSDDEEKNKQNKTKTQTS----DSSE 460

Query: 2113 PNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLE 2172
                          +  +   +  P    +  SD   +  +     + RQ     K +  
Sbjct: 461  GKT-----------KSVRHAYVHKPYLYSKYYSDSDDELTVE----QRRQSIAKEKEERL 505

Query: 2173 DELKDDAQSVETLGKPKAKRIRTSKTK---QASKNTEKESAWSPPPIEIRLISPLASPAD 2229
               + + + +E   K KA++ ++SKTK   ++S + E+ S  S  P   R+   L     
Sbjct: 506  LRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVL----- 560

Query: 2230 GVKSKPRKTTEVTGTGLGRNRKKLSSYPKQILRRK 2264
                K RK  E     L + RKK S   ++  ++K
Sbjct: 561  ----KERKVLE-KKVALSKKRKKDSRNVEENSKKK 590



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 128/631 (20%), Positives = 233/631 (36%), Gaps = 85/631 (13%)

Query: 1281 LNSPEKEHQEMDEGSQSLEKLDVSKGNSSVSITSDETTLEYQDAPSPEDL---EETVFTA 1337
            LNS +KE +  + G+          G SS +  S    LE  +A SP  L   E+T    
Sbjct: 2466 LNSLQKEDKSPETGTA---------GGSSTASYSAGRGLE-GNANSPAHLRGPEQTSGQT 2515

Query: 1338 SKPKSSSTALTTNVTEQTEKDGDKDVFASEVT-----PSDLQKQMGNLEDAETKDLLVAA 1392
            +K  S S      V     K  D       V      P++ Q    NL+ + TK +    
Sbjct: 2516 AKDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHSFLPAEQQGSEDNLKTSTTKCITGQE 2575

Query: 1393 EAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVETYTPAIRANDNKS 1452
               +  + + P      +L AP   +             D+          A +  D+ S
Sbjct: 2576 SKIAPSHTMIPPATYSVALLAPKCEQDLTIKNDYSGKWTDQA--------SAEKTGDDNS 2627

Query: 1453 MADVLGDGGNSSLTISEGPIVSERRLNQEVALNLKEDHEVEVGVLKES-VDLPEEKLPIS 1511
                  + G+  +T+S    V +   N+E  LN+    +++  +  E+ V   EEK    
Sbjct: 2628 TRKSFPEEGDIMVTVSSEENVCDIG-NEESPLNVLGGLKLKANLKMEAYVPSEEEKNGEI 2686

Query: 1512 DSPPDT------------QEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDT 1559
             +PP++            Q   ++  E L  ++SG        +E Y  G +      D 
Sbjct: 2687 LAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSESYNKGEISSGRK-DN 2745

Query: 1560 IDQQFCDLADNKDTAECDIAEVDGEL--FVAQSNFTLILEGEEGEVEPGDFASSDVLPKA 1617
             +      A +  + E D  EV+ E      +      L  E+   EP D  + DVL   
Sbjct: 2746 AE------AISGHSVEADPKEVEEEERHMPKRKRKQHYLSSED---EPDD--NPDVLDSR 2794

Query: 1618 ANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIK 1677
              TA  +      E + H          T ++ S+ ++ LP        +    +++   
Sbjct: 2795 IETAQRQ----CPETEPHD---------TKEENSRDLEELPKTSSETN-STTSRVMEEKD 2840

Query: 1678 DTRSKEITSDTMEQSIHETIP--------LVSQNIMCPTKL-VKSAFKTAQETSTMTMNV 1728
            +  S E T +  EQ+  +TI         ++ +    P K  V++  K   ++ T T  V
Sbjct: 2841 EYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIV 2900

Query: 1729 SQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASEN 1788
            +      SSK +       N    + Q+ + ++    +    SVR++ RK K     S++
Sbjct: 2901 TVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDD 2960

Query: 1789 IYSDVRGLSQNQQIPQNSVT-PRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSS 1847
              S     S+ ++  Q SV+ P   ++++E +++  E            +   S+  +S 
Sbjct: 2961 AES-----SEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRSK 3015

Query: 1848 QLLEPAVEETTKKEVKVSSVTKRTPRRIKRS 1878
              L P+++   K+EV       R  +R++ +
Sbjct: 3016 TQLSPSIKR--KREVSPPGARTRGQQRVEEA 3044



 Score = 38.5 bits (88), Expect = 0.076
 Identities = 52/230 (22%), Positives = 90/230 (39%), Gaps = 41/230 (17%)

Query: 1900 SRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQL 1959
            SR + +L  T+ + +  T    ++K                 E S S+   +   ++   
Sbjct: 2815 SRDLEELPKTSSETNSTTSRVMEEKD----------------EYSSSETTGEKPEQNDDD 2858

Query: 1960 TV--QAEFDMSAIPRKRGRPRKI----------NPSEDVGSKAVKEERSPKKKEAPSI-- 2005
            T+  Q E     I RKRGRPRK           +   D G   V++  S  K +      
Sbjct: 2859 TIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDE 2918

Query: 2006 RRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQS---QKRSLH 2062
              + T N   +S + D G+  +  S+     +       K+ LT   +++S   +++   
Sbjct: 2919 SNKETANLQERSISNDDGEEKIVTSVRRRGRK------PKRSLTVSDDAESSEPERKRQK 2972

Query: 2063 SVSEERTD--EMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDL 2110
            SVS+   D  E    E  E+EE    + + T+S+  S  + SK  L P +
Sbjct: 2973 SVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRSKTQLSPSI 3022



 Score = 33.5 bits (75), Expect = 2.4
 Identities = 48/212 (22%), Positives = 83/212 (39%), Gaps = 32/212 (15%)

Query: 2013 TPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEM 2072
            TP  S NV     ++ ++I   N+E S   +S +    KT  ++ K+     S+  TD  
Sbjct: 190  TPGPSANVANDAMSILETITSLNQEASAARASTETSNAKTSERASKKL---PSQPTTDTS 246

Query: 2073 THKETNEQE--ERLLATASFTKSSRSSRTRSSKAILLPD--------LSEPNNEPLFSP- 2121
            T KE   ++  ++  +TA        +  +S +   LP           E NN  L +  
Sbjct: 247  TDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKD 306

Query: 2122 ----ASEVPRKAKAKKIEVP------AQLKELVSDLSSQFVISPPALRSRQKNTSNKNKL 2171
                +SE   K+  K  + P       + KE       +F           K + +  K+
Sbjct: 307  VQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKF--------DHSKKSEDTQKV 358

Query: 2172 EDELKDDAQSVETLGKPKAKRIRTSKTKQASK 2203
            +DE +   + VE+L  P  K    +KT + +K
Sbjct: 359  KDEKQAKEKEVESLKLPSEKNSNKAKTVEGTK 390



 Score = 32.3 bits (72), Expect = 5.4
 Identities = 40/203 (19%), Positives = 81/203 (39%), Gaps = 8/203 (3%)

Query: 1716 KTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVR-- 1773
            KT+ ET++ T  V +  D  SS   T  +  QN +     QE    +   +  G+  +  
Sbjct: 2823 KTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYP 2882

Query: 1774 -KKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVN-QDILENTSSVEQ 1831
             + T K K+ S+    I +    + Q+    +  V       K+  N Q+   +    E+
Sbjct: 2883 VETTLKMKDDSKTDTGIVT----VEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEE 2938

Query: 1832 ELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDL 1891
            ++  +  R  ++ K S  +    E +  +  +  SV+     + ++  + +E  E  ++ 
Sbjct: 2939 KIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEP 2998

Query: 1892 KVSTVTSPSRMIRKLRSTNLDAS 1914
              +T  S +R   +   T L  S
Sbjct: 2999 SGATTRSTTRSEAQRSKTQLSPS 3021


>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
          Length = 710

 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 136/665 (20%), Positives = 254/665 (38%), Gaps = 85/665 (12%)

Query: 1604 EPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEP 1663
            +P + A+SD     +N ATE K     E    G ++    +       +KV  L  +   
Sbjct: 97   QPAEKATSDEKDSVSNIATEIK-----EGQQSGTVSPQKQSAQKVIFKKKVSLLN-IATR 150

Query: 1664 IKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPT--KLVKSAFK-TAQE 1720
            I        +   K   SK  +  T   S   T   +   + C T     + A K T  E
Sbjct: 151  IMGGGKSGTVSSQKQPASKTASDKT--DSALNTATEIKDGLQCGTVSSQKQQALKATTDE 208

Query: 1721 TSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVR----KKT 1776
              +++   +++ D   S T    Q+   +   S ++++ +++   K  G+  R    +K 
Sbjct: 209  EGSVSNIATEIKDGEKSGT-VSSQKKPALKATSDEKDSFSNITREKKDGEISRTVSSQKP 267

Query: 1777 RKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQIT 1836
               K  S   +++ +  R     ++    S     G +     +D L N +  ++     
Sbjct: 268  PALKATSVKEDSVLNIAREKKDGEKSRTVSFDQPPGLKATRDEKDSLLNIARGKKN---- 323

Query: 1837 TGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTV 1896
             G +++R+ S +  +PA++ T+ ++   S++T+            ++  EI    KVS+ 
Sbjct: 324  -GEKTRRVSSRK--KPALKATSDEKDSFSNITR-----------GKKDGEISR--KVSSQ 367

Query: 1897 TSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLES 1956
              P+     L+ T+ +     G  +++K  +K    + V   +   +  S   +DS L  
Sbjct: 368  KPPT-----LKGTSDEEDSVLGIARENKDGEKS---RTVSSEKPPGLKASSDEKDSVLNI 419

Query: 1957 SQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAK 2016
            ++     E       RK+      +  +D  S   +E     KK+    R+ S++  PA 
Sbjct: 420  ARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITRE-----KKDGEISRKVSSQKPPAL 474

Query: 2017 SENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTH-- 2074
                D     LG +    + E S  +SS+K    K  S  +   L+    ++  E T   
Sbjct: 475  KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIARGKKDGEKTRTV 534

Query: 2075 --------KETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVP 2126
                    K T+++++ +L  A   K    SRT SS+        +P  + +      VP
Sbjct: 535  SSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQ-------KQPALKAICDKEDSVP 587

Query: 2127 RKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLG 2186
              A  KK E      ++   +SSQ     PAL++      + + +  E+KD  QS    G
Sbjct: 588  NMATEKKDE------QISGTVSSQ---KQPALKATSDKKDSVSNIPTEIKDGQQS----G 634

Query: 2187 KPKAKRIRTSKTKQASKNTEKESAWSPPPIEIR-LISPLASPADGVKSKPRKT-----TE 2240
               +++    K     K++    A      +IR  +SP    A  V  K + +     T 
Sbjct: 635  TVSSQKQPAWKATSVKKDSVSNIATEIKDGQIRGTVSPQKQSAQKVIFKKKVSLLNIATR 694

Query: 2241 VTGTG 2245
            +TG G
Sbjct: 695  ITGGG 699


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
            containing B [Homo sapiens]
          Length = 546

 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 76/326 (23%), Positives = 130/326 (39%), Gaps = 31/326 (9%)

Query: 1762 VATPKMPGQSVRKKTRKAKEIS-EASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQ 1820
            V   K   Q ++ + RK K+   E +E I   V    +  + P+ S++PRR  R+     
Sbjct: 223  VPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVE--RRRSRSPRRSLSPRRSPRRSRSRS 280

Query: 1821 DILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVE 1880
               E   S   +      RE +R K  Q LE   +E  K+  +  S+ +   RR  RS E
Sbjct: 281  HHREGHGSSSFD------RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRE 334

Query: 1881 NQESVEIINDLKVSTVTSPSRMIRKL---RSTNLDASENTGNKQDDKSSDKQLRIKHVRR 1937
               S     D K           ++    R  + D  +  GN+++ +    + R K  +R
Sbjct: 335  RHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKE-QR 393

Query: 1938 VRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSP 1997
             RG EV     +ED +    +   +         R R R RK + S      A K  RS 
Sbjct: 394  SRG-EVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERK-HRSRSRSRNAGKRSRSR 451

Query: 1998 KKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQ 2057
             K+++   +  S   +  +S +   G+                V  SKK+    ++ +S+
Sbjct: 452  SKEKSSKHKNESKEKSNKRSRSGSQGRT-------------DSVEKSKKREHSPSKEKSR 498

Query: 2058 KRSLHSVSEERTDEMTHKETNEQEER 2083
            KRS    S+ER+ +  H ++ +Q ++
Sbjct: 499  KRSR---SKERSHKRDHSDSKDQSDK 521


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
            [Homo sapiens]
          Length = 651

 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 97/474 (20%), Positives = 173/474 (36%), Gaps = 59/474 (12%)

Query: 1751 VKSAQQEASADVATPKMPGQSVRKKTRKAKE-----ISEASENIYSDV-RGLSQNQQIPQ 1804
            +K   ++     AT     Q V +KT++  E     +  + EN  S   +  S+     Q
Sbjct: 127  LKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQ 186

Query: 1805 NSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKV 1864
            NS T  +   +K+      +N+     E   T     K LK S+     + E   +    
Sbjct: 187  NSKTVSKNCSQKDKKDS--KNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSE---- 240

Query: 1865 SSVTKRTPRRIKRSVENQESVEIINDLK-VSTVTSPSRMIRKLRSTNLDASENTGNKQDD 1923
            +S+       + +S  + ES+     L+  S   S +  ++  + T  D  +N     D 
Sbjct: 241  NSLNVDFLMLVGQS--DDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDA 298

Query: 1924 KSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPS 1983
            +S D +   K  ++V+ + V   D ++D   ++   +  AE   S   RK  +  K    
Sbjct: 299  ESEDSKDAKKDSKKVK-KNVKKDDKKKDVKKDTE--STDAESGDSKDERKDTKKDKKKLK 355

Query: 1984 EDVGSKAVKEERSPKKKEAPSIR--RRSTRNTPAKSENVDVGKPALGKSILVPNEELSMV 2041
            +D   K  K+       E+   +  R  +RN    S+N D  K A               
Sbjct: 356  KDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDA--------------- 400

Query: 2042 MSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRS 2101
                KK+T  T+S+S+  S  S  +E+ D+   K  N++           K+   S    
Sbjct: 401  ----KKITFSTDSESELESKESQKDEKKDKKDSKTDNKKS---------VKNDEESTDAD 447

Query: 2102 SKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELV--SDLSSQFVISPPALR 2159
                     SEP  +       E   K  +KK +     K+    +++ S   +      
Sbjct: 448  ---------SEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKH 498

Query: 2160 SRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSP 2213
            S++K  S K+  +D  KD   +     +      +TS   + S    +ES + P
Sbjct: 499  SKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKP 552


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
            sapiens]
          Length = 699

 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 116/563 (20%), Positives = 209/563 (37%), Gaps = 99/563 (17%)

Query: 1675 VIKDTRSKEITSDTMEQSIHETIPL--VSQNIMCPTKLV-----KSAFKTAQETSTMTMN 1727
            V K  + K  +SD+ + S  E       ++    P K V     K+A K ++ +S+    
Sbjct: 74   VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEES- 132

Query: 1728 VSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASE 1787
             S  DD    K     Q +Q    K  + +A A  A PK           KAK     S+
Sbjct: 133  -SDDDDEEDQKK----QPVQ----KGVKPQAKAAKAPPK-----------KAKSSDSDSD 172

Query: 1788 NIYSDVRGLSQNQQIP------QNSVTPRRGRRKKEV-NQDILENTSSVEQELQITTGRE 1840
            +   D    +Q  +I       Q    P+  R   ++ N     ++SS           E
Sbjct: 173  SSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEE 232

Query: 1841 SKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLK-------- 1892
             K   + +   P  +   K  VK ++    TP R   S E+  S E     K        
Sbjct: 233  EKAAATPKKTVPKKQVVAKAPVKAAT----TPTRKSSSSEDSSSDEEEEQKKPMKNKPGP 288

Query: 1893 VSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDS 1952
             S+V  PS    K         ++ G +   K+ +KQ      + V   E S SD  + S
Sbjct: 289  YSSVPPPSAPPPK---------KSLGTQPPKKAVEKQ------QPVESSEDS-SDESDSS 332

Query: 1953 NLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRN 2012
            + E  +   +A    +       +    + S+   S + +++ +P K   P+   +++ N
Sbjct: 333  SEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSK---PAGTTKNSSN 389

Query: 2013 TPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEM 2072
             PA +      KPA              V   +K LT+K +S S +    S  EE+T +M
Sbjct: 390  KPAVTTKSPAVKPAAAPK--------QPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKM 441

Query: 2073 THKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAK 2132
                  +   +   +    ++ + SR  SS      D    ++E      S+   K K +
Sbjct: 442  VATTKPKATAKAALSLPAKQAPQGSRDSSS------DSDSSSSEEEEEKTSKSAVKKKPQ 495

Query: 2133 KIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKR 2192
            K+   A   +            P + +  +  +SN +  +D  +++ + ++  G P+ + 
Sbjct: 496  KVAGGAAPSK------------PASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQA 543

Query: 2193 IR-------TSKTKQASKNTEKE 2208
             +       T++  +A+KN+E+E
Sbjct: 544  PKANGTSALTAQNGKAAKNSEEE 566



 Score = 40.4 bits (93), Expect = 0.020
 Identities = 87/512 (16%), Positives = 177/512 (34%), Gaps = 21/512 (4%)

Query: 1639 ANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIP 1698
            A    + +S++ S   D      +P++  +        K    K  +SD+   S  E  P
Sbjct: 121  AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQA-KAAKAPPKKAKSSDSDSDSSSEDEP 179

Query: 1699 LVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEA 1758
              +Q        VK+  K   + +     ++      SS + +      +   + A    
Sbjct: 180  PKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239

Query: 1759 SADV----ATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRR 1814
               V       K P ++    TRK+    ++S +   + +   +N+  P +SV P     
Sbjct: 240  KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPP 299

Query: 1815 KKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRR 1874
             K+ +        +VE++  + +  +S     S   E   E+    +  VS  T + P  
Sbjct: 300  PKK-SLGTQPPKKAVEKQQPVESSEDSSDESDSSSEE---EKKPPTKAVVSKATTKPPPA 355

Query: 1875 IKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKH 1934
             K +  + +S +  +       + P+   +   S+N  A           ++ KQ  +  
Sbjct: 356  KKAAESSSDSSDSDSSEDDEAPSKPAGTTKN--SSNKPAVTTKSPAVKPAAAPKQ-PVGG 412

Query: 1935 VRRVRGREVSPSDVREDSNLESSQLTVQAEFDMS---------AIPRKRGRPRKINPSED 1985
             +++  R+   S   E+S+    + T +               ++P K+      + S D
Sbjct: 413  GQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSD 472

Query: 1986 VGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSK 2045
              S + +EE     K A   + +      A S+     K     S    +++ S     K
Sbjct: 473  SDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532

Query: 2046 KKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAI 2105
             K       Q+ K +  S    +  +       E+EE+  A    +KS    + + ++A 
Sbjct: 533  LKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA 592

Query: 2106 LLPDLSEPNNEPLFSPASEVPRKAKAKKIEVP 2137
               +  +     L +P +   RK   K+   P
Sbjct: 593  KEAETPQAKKIKLQTPNTFPKRKKGEKRASSP 624



 Score = 32.7 bits (73), Expect = 4.2
 Identities = 51/227 (22%), Positives = 85/227 (37%), Gaps = 36/227 (15%)

Query: 2035 NEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSS 2094
            + +LS V +   K T  T+  +   SL  +          K     E +L A     K +
Sbjct: 24   DNQLSEVANKFAKATGATQQDANASSLLDIYS-----FWLKSAKVPERKLQANGPVAKKA 78

Query: 2095 RSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVIS 2154
            +   + S       D SE   E    PA         KK  VPA+   L           
Sbjct: 79   KKKASSSDSE----DSSEEEEEVQGPPA---------KKAAVPAKRVGL----------- 114

Query: 2155 PP---ALRSRQKNTSNKNKLEDELKDDA-QSVETLGKPKAKRIRT--SKTKQASKNTEKE 2208
            PP   A ++ + ++S ++  +D+ +D   Q V+   KP+AK  +    K K +  +++  
Sbjct: 115  PPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSS 174

Query: 2209 SAWSPPPIEIRLISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSS 2255
            S   PP  +   I+P+   A   K+ P+          G+     SS
Sbjct: 175  SEDEPPKNQKPKITPVTVKAQ-TKAPPKPARAAPKIANGKAASSSSS 220


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 73/332 (21%), Positives = 128/332 (38%), Gaps = 32/332 (9%)

Query: 1842 KRLKSSQLLEPAVEETTKKEVKVSS------VTKRTPRRIKRSVENQESVEIINDLKVST 1895
            +R  S + L+PA +    K V+  S      VTK         VE++E V +  D  + T
Sbjct: 537  QRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKT 596

Query: 1896 VTSPSRMIRKLRSTN--LDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSN 1953
             T PS   +++ S             KQ      K  + K V+  +  +V P D +E+  
Sbjct: 597  ETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVK--KETKVKPEDKKEEK- 653

Query: 1954 LESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEE-RSPKKKEAPSIRRRSTRN 2012
             E  +  V  + D + I +K  +P+K    ++V  +  KEE + PKK+       +  + 
Sbjct: 654  -EKPKKEVAKKEDKTPI-KKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKK 711

Query: 2013 TPAKSENVDVGK------------PALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRS 2060
               K E  +V K            P   K    P  E     + K K+ KK ES  +   
Sbjct: 712  EVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSV 771

Query: 2061 LHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFS 2120
                 +E+      K+  +  E + A      ++ +    +  A + P         L S
Sbjct: 772  AAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMS 831

Query: 2121 PASEVPR---KAKAKKIEVPAQLK---ELVSD 2146
               ++ +   + KA++++V   +K   EL+ D
Sbjct: 832  SPEDLTKDFEELKAEEVDVTKDIKPQLELIED 863



 Score = 37.7 bits (86), Expect = 0.13
 Identities = 47/269 (17%), Positives = 106/269 (39%), Gaps = 26/269 (9%)

Query: 1867 VTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSS 1926
            +T + P  + +  + ++  +    LK +    PS+ +RK      ++ E T         
Sbjct: 521  LTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRK------ESKEETPEVTKVNHV 574

Query: 1927 DKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDV 1986
            +K  +++   +V  ++  P  ++ ++    ++  V ++ + S +  +    +    + DV
Sbjct: 575  EKPPKVESKEKVMVKKDKP--IKTETKPSVTEKEVPSKEEPSPVKAEVAEKQ----ATDV 628

Query: 1987 GSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKK 2046
              KA KE+   K+ +     ++  +  P K       K  + K      EE+      KK
Sbjct: 629  KPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEV------KK 682

Query: 2047 KLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAIL 2106
            ++ K+ + + +K     V +E   +   KE  ++E++        K  +  +    K   
Sbjct: 683  EVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKK-----EVKKEEKEPKKEIKK--- 734

Query: 2107 LPDLSEPNNEPLFSPASEVPRKAKAKKIE 2135
            LP  ++ ++ PL         K K  K E
Sbjct: 735  LPKDAKKSSTPLSEAKKPAALKPKVPKKE 763



 Score = 35.4 bits (80), Expect = 0.64
 Identities = 102/528 (19%), Positives = 190/528 (35%), Gaps = 78/528 (14%)

Query: 1244 PGAADDSKLEVFTTPKKCAVPVETEWLKSKD---RTTSFFLNSPEKEHQEMDEGSQSLEK 1300
            P     S L      K  AVPV  E+  +KD   R +   ++ P  + +   E   S  +
Sbjct: 1340 PTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSPMDEPVPDSESPIEKVLSPLR 1399

Query: 1301 LDVSKGNSSV--SITSDETTLEYQDAPSPEDLEETVFTASKPKSSSTALTTNVTEQTEKD 1358
                 G+ S   S  S +     + A SP + +     +    S  + +T+    Q +++
Sbjct: 1400 SPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQGSPDQVSPVSEMTSTSLYQDKQE 1459

Query: 1359 GDKDVFASEVTPSDLQKQMGNLEDAETKDLLVAAEAFSELNHLSPVQ------GTEASLC 1412
            G    FA        +K+  ++E   ++  L   E   +L  +SP Q      G+     
Sbjct: 1460 GKSTDFAPIKEDFGQEKKTDDVEAMSSQPALALDER--KLGDVSPTQIDVSQFGSFKEDT 1517

Query: 1413 APSVYEGKIFTQKSKVPVLDEGLTSVETYTPAIRANDNKSMADVLGDGGNSSLTISEGPI 1472
              S+ EG + + KS  PV DEG+           A D  S  + +     +S+  S  P 
Sbjct: 1518 KMSISEGTV-SDKSATPV-DEGV-----------AEDTYSHMEGVASVSTASVATSSFPE 1564

Query: 1473 VSERRLNQEVALNLKEDHEVEV------GVLKESVDLPEEKL---------PISDSPPDT 1517
             +   ++  +   +   H  EV       V++      E ++         P+S SPPD 
Sbjct: 1565 PTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISPPDF 1624

Query: 1518 QEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECD 1577
                   +  ++   S + + ++ F +  P  +L + ++  + D                
Sbjct: 1625 SPKTAKSRTPVQDHRSEQSSMSIEFGQESPEQSLAMDFSRQSPDHPTVGA---------- 1674

Query: 1578 IAEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAA----------NTATEEKLV 1627
                 G L + ++  T      E +  P D   S +  K            N  +E   V
Sbjct: 1675 -----GVLHITENGPT------EVDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISV 1723

Query: 1628 CSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLL-DVIKDTRSKEIT- 1685
               E       A+ PS + S  +    DTL  V  P  +++  +L  + ++    ++++ 
Sbjct: 1724 SQVEASPSTSSAHTPSQIASPLQE---DTLSDVAPPRDMSLYASLTSEKVQSLEGEKLSP 1780

Query: 1686 -SDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVD 1732
             SD    +  E+ PL S      T  VK    T   +S+  ++ +  +
Sbjct: 1781 KSDISPLTPRESSPLYSPTFSDSTSAVKEKTATCHSSSSPPIDAASAE 1828



 Score = 33.9 bits (76), Expect = 1.9
 Identities = 48/236 (20%), Positives = 91/236 (38%), Gaps = 31/236 (13%)

Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATAS-F 2090
            +V   +L     S++ L K        +S+   S+E T E+T     E+  ++ +     
Sbjct: 529  VVKQTKLKQRADSRESL-KPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVM 587

Query: 2091 TKSSRSSRTRSSKAIL---LPDLSEPNN---EPLFSPASEV-PRKAKAKKIEVPAQLKEL 2143
             K  +  +T +  ++    +P   EP+    E     A++V P+ AK K ++   ++K  
Sbjct: 588  VKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKP- 646

Query: 2144 VSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASK 2203
                              +K    K K E   K+D   ++   KPK + ++    K+  K
Sbjct: 647  ----------------EDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKK 690

Query: 2204 NTEKESAWSPPPIEIRLISPLASPADGVKSKPRKTTEVTGTGLGRNRKKLSSYPKQ 2259
              +KE     P  E++  +P       VK + +K  +       +  KKL    K+
Sbjct: 691  EEKKE-----PKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKK 741



 Score = 33.5 bits (75), Expect = 2.4
 Identities = 94/583 (16%), Positives = 223/583 (38%), Gaps = 62/583 (10%)

Query: 1652 QKVDTLPYVPEPI---KVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPT 1708
            +K+  L ++ +P+   K    +    V+K T+ K+  +D+ E       PL S+++   +
Sbjct: 503  EKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQ-RADSRESLKPAAKPLPSKSVRKES 561

Query: 1709 KLVKSAFKTAQETSTMT-MNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKM 1767
            K         +ET  +T +N  +    V SK +   ++ + +  ++       +V + + 
Sbjct: 562  K---------EETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEE 612

Query: 1768 PG----QSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDIL 1823
            P     +   K+    K  +   + +  + +   ++++  +    P++   KKE    I 
Sbjct: 613  PSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKK--EEKEKPKKEVAKKEDKTPIK 670

Query: 1824 ENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQE 1883
            +     ++E++    +E K+ +  +  +   +ET  KEVK     K   +  K+ V+ +E
Sbjct: 671  KEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVK-----KEVKKEEKKEVKKEE 725

Query: 1884 SVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDK--SSDKQLRIKHVRRVRGR 1941
                           P + I+KL     DA +++    + K  ++ K    K    V+  
Sbjct: 726  K-------------EPKKEIKKLPK---DAKKSSTPLSEAKKPAALKPKVPKKEESVKKD 769

Query: 1942 EVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKE 2001
             V+    +E   ++  +   +A   ++A          +  +  + +    +E   ++  
Sbjct: 770  SVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSL 829

Query: 2002 APSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEE-------LSMVMSSKKKLTKKTES 2054
              S    +      K+E VDV K    +  L+ +EE       +   +  K++   K  +
Sbjct: 830  MSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPA 889

Query: 2055 QSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPN 2114
            +S    + +   E   E T +E    E++ +      +   +    SS+       +   
Sbjct: 890  ESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSE-------TGDY 942

Query: 2115 NEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDE 2174
             E   +  +E P +   + + V A       D  S    +   +R ++++ ++ +   +E
Sbjct: 943  EEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEE 1002

Query: 2175 LKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIE 2217
              D+A     + K +A++      ++      +E  + P  +E
Sbjct: 1003 DMDEA-----IEKGEAEQSEEEADEEDKAEDAREEEYEPEKME 1040


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
            sapiens]
          Length = 1220

 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 84/523 (16%), Positives = 203/523 (38%), Gaps = 71/523 (13%)

Query: 1710 LVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPG 1769
            L     K  +ET  +    +  ++  S   + +GQ+ +  +      E   D        
Sbjct: 67   LEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED-------- 118

Query: 1770 QSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSV-TPRRGRRKKEVNQDILENTSS 1828
                 K  K+K+ ++    +YS         ++P+ +    ++  +K + +++  +N+  
Sbjct: 119  -----KDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKK 173

Query: 1829 VEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEII 1888
            +++  +I +  ES   +S + L+      ++K  K +   K  P  I+   E+ ++    
Sbjct: 174  IKERSRINSSGESGD-ESDEFLQ------SRKGQKKNQKNKPGPN-IESGNEDDDA---- 221

Query: 1889 NDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDV 1948
               K+ TV               +  E    K+D++ +        +R+++ +E   +  
Sbjct: 222  -SFKIKTVAQKKA----------EKKERERKKRDEEKAK-------LRKLKEKEELETGK 263

Query: 1949 REDSNLESSQLTVQAE-------FDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKE 2001
            ++ S  + SQ   + E        D   IP    +      +ED      K++   KKK 
Sbjct: 264  KDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG 323

Query: 2002 APSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSL 2061
                + +  +  P+K+  V   + AL K   +  EE       ++++ +  E +++++  
Sbjct: 324  EKEEKEKEKKKGPSKA-TVKAMQEALAK---LKEEEERQKREEEERIKRLEELEAKRKEE 379

Query: 2062 HSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDL---------SE 2112
              + +E+ +    KE   +E         TKS R +R R+   + L            S 
Sbjct: 380  ERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSL 439

Query: 2113 PNNEPLF--SPASEVPRKAKAKKIEVPAQL---KELVSDLSSQFVISPPALRSRQKNTSN 2167
            P   P++      ++P++ ++K++    +L    E++     +   +PP +   ++  + 
Sbjct: 440  PKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTE 499

Query: 2168 KNKLED--ELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKE 2208
               L+D   +  D ++ +  G      ++ +  ++  +  E+E
Sbjct: 500  DAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEE 542



 Score = 32.7 bits (73), Expect = 4.2
 Identities = 64/359 (17%), Positives = 126/359 (35%), Gaps = 47/359 (13%)

Query: 1737 SKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGL 1796
            SK +   ++ +   VKS        V T  +P    + +T  A E     +    D +  
Sbjct: 267  SKQKESQRKFEEETVKS-----KVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKK 321

Query: 1797 SQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEE 1856
               ++  +     ++G  K  V   + E  + +++E +     E +R+K  + LE   +E
Sbjct: 322  KGEKE--EKEKEKKKGPSKATVKA-MQEALAKLKEEEERQKREEEERIKRLEELEAKRKE 378

Query: 1857 TTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASEN 1916
              + E        +  R  K+  E +    +  + K+  +T   R  R      L   + 
Sbjct: 379  EERLE--------QEKRERKKQKEKERKERLKKEGKL--LTKSQREARARAEATLKLLQA 428

Query: 1917 TGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGR 1976
             G +   K S  + R   +   + R+  P  +      ES +L    E     +P K   
Sbjct: 429  QGVEVPSKDSLPKKR--PIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEET 486

Query: 1977 PRKINPSED-----------------------VGSKA-VKEERSPKKKEAPSIRRRSTRN 2012
            P  + P E+                        G+K  ++ + +P+++E           
Sbjct: 487  PPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEE 546

Query: 2013 TPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDE 2071
            +  + E     + + G      +E++S    S K L KK   +    S +   ++RT E
Sbjct: 547  SEEEEEEEGESEGSEGDE---EDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKE 602


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 96/448 (21%), Positives = 167/448 (37%), Gaps = 52/448 (11%)

Query: 1773 RKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQE 1832
            +++  + K  S   ++   D R   + +   +     R  RR+K  +      +S V +E
Sbjct: 133  QRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRE 192

Query: 1833 LQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLK 1892
             + +  R  +    S+   PA E   KKE        +TP   + SV+       + +  
Sbjct: 193  RKRSHSRSPRHRTKSRSPSPAPE---KKE--------KTPELPEPSVK-------VKEPS 234

Query: 1893 VSTVTSPSRMIRKLRSTNL-DASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVRED 1951
            V   TS S +++  +   + +  E +  K   K  +K+   K   R R R  S S  R  
Sbjct: 235  VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKE---KTRPRSRSRSKSRSRTRSR 291

Query: 1952 SNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTR 2011
            S   +           S  PR+R  PR+  PS    +   +    P+ + + S  RR  R
Sbjct: 292  SPSHTRPRRRHRSRSRSYSPRRRPSPRR-RPSPRRRTPPRRMPPPPRHRRSRSPVRRRRR 350

Query: 2012 NTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERT-- 2069
            ++ + S +      +  +S   P +      S  +K  + + S S  R  H  S   T  
Sbjct: 351  SSASLSGSSSSSSSSRSRS--PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP 408

Query: 2070 DEMTHKETNEQEERLLATASFTKSSRSSRT--RSSKAILLPDLSEPNNEPLFSPASEVPR 2127
             +  H  T +Q  R       T+ SR S +  R+S  +     +E    P  SPA + PR
Sbjct: 409  PKTRHSPTPQQSNR-------TRKSRVSVSPGRTSGKVTKHKGTEKRESP--SPAPK-PR 458

Query: 2128 KAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGK 2187
            K          +L E   D   +   +    + RQ    N+    D     +   E   +
Sbjct: 459  K---------VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE---R 506

Query: 2188 PKAKRIRTSKTKQASKNTEKESAWSPPP 2215
            PK   ++  +  +  +++   SA SP P
Sbjct: 507  PKRSHVKNGEVGRRRRHSPSRSA-SPSP 533



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 74/327 (22%), Positives = 126/327 (38%), Gaps = 62/327 (18%)

Query: 1912 DASENTGNKQDDKSS-DKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAI 1970
            D  ++  +K++ +SS +K+ R +  RR + R  SP          SS +  + +   S  
Sbjct: 148  DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP-------RRRSSPVRRERKRSHSRS 200

Query: 1971 PRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRR--STRNTPAKSENVDVGKPALG 2028
            PR R + R  +P+ +      K+E++P+  E PS++ +  S +   + S+ + V KP   
Sbjct: 201  PRHRTKSRSPSPAPE------KKEKTPELPE-PSVKVKEPSVQEATSTSDILKVPKP--- 250

Query: 2029 KSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATA 2088
            + I  P E      S K+K  +KT  +S+ RS    S  RT   +   T  +      + 
Sbjct: 251  EPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSK---SRSRTRSRSPSHTRPRRRHRSRSR 307

Query: 2089 SFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLS 2148
            S++   R S               P   P  SP    P     +++  P + +   S   
Sbjct: 308  SYSPRRRPS---------------PRRRP--SPRRRTP----PRRMPPPPRHRRSRS--- 343

Query: 2149 SQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKE 2208
                   P  R R+ + S            + S  +   PK    RTS      + T + 
Sbjct: 344  -------PVRRRRRSSASLSGS-----SSSSSSSRSRSPPKKPPKRTSSPP---RKTRRL 388

Query: 2209 SAWSPPPIEIRLISPLASPADGVKSKP 2235
            S  + PP      SP A+P    +  P
Sbjct: 389  SPSASPPRRRHRPSPPATPPPKTRHSP 415



 Score = 39.7 bits (91), Expect = 0.034
 Identities = 79/407 (19%), Positives = 149/407 (36%), Gaps = 49/407 (12%)

Query: 1764 TPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQ-NSVTPRRGRRKKEVNQDI 1822
            TP++P  SV+ K    +E +  S     D+  + + + IP+    +P +  +K++  +  
Sbjct: 220  TPELPEPSVKVKEPSVQEATSTS-----DILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT 274

Query: 1823 LENTSSVEQELQITTGRES-----KRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKR 1877
               + S  +    T  R       +R   S+    +         + S   +  PRR+  
Sbjct: 275  RPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP 334

Query: 1878 SVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQ---LRIKH 1934
               ++ S             SP R  R+  S +L  S ++ +    +S  K+        
Sbjct: 335  PPRHRRS------------RSPVRR-RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381

Query: 1935 VRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVG--SKAVK 1992
             R+ R    S S  R   +  S   T   +   S  P++  R RK   S   G  S  V 
Sbjct: 382  PRKTRRLSPSASPPRR-RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440

Query: 1993 EERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKT 2052
            + +  +K+E+PS   +  +   ++SE    GK A   S+             +++  ++ 
Sbjct: 441  KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV-----------QQRRQYRRQN 489

Query: 2053 ESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSE 2112
            +  S      S SE+   + +H +  E   R   + S   +S S R R  +       + 
Sbjct: 490  QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS-RSASPSPRKRQKE-------TS 541

Query: 2113 PNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALR 2159
            P      SP+    R+ ++     P + +   +    +   SPP  R
Sbjct: 542  PRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 86/441 (19%), Positives = 165/441 (37%), Gaps = 60/441 (13%)

Query: 1769 GQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSS 1828
            GQ V ++    K  ++A+   +++VR LS  + IP++ V       KKE  +    ++SS
Sbjct: 147  GQEVVREIENQK--TDAASKPFAEVRILSCGELIPKSKV-------KKEEKKRHKSSSSS 197

Query: 1829 VEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEII 1888
                    +  +S+    S   E A EE +KK  K      R  ++ K+  +  +     
Sbjct: 198  SSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASS 257

Query: 1889 NDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDV 1948
                 +    P   +R      +  +     K   K+ +K+   K+  R R RE +P + 
Sbjct: 258  ESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER--KNRERERERECNPPN- 314

Query: 1949 REDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRR 2008
                       +  A +    +  + GR  K               R P++   PS  R 
Sbjct: 315  -----------SQPASYQRRLLVTRSGRKIK--------------GRGPRRYRTPS--RS 347

Query: 2009 STRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEER 2068
             +R+   +SE     +  + ++         M +SS ++  K       K  L+ + E +
Sbjct: 348  RSRDRFRRSETPPHWRQEMQRA-------QRMRVSSGERWIK-----GDKSELNEIKENQ 395

Query: 2069 TDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRK 2128
               +  KE    + R ++ +   K+ +  + +  K+         N+E      ++V ++
Sbjct: 396  RSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKR 455

Query: 2129 AKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKP 2188
            AK+K      +  +     S         +RSR K   ++N  E E + D+         
Sbjct: 456  AKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDS--------- 506

Query: 2189 KAKRIRTSKTKQASKNTEKES 2209
            K K    S++K+ SK  E +S
Sbjct: 507  KGKDQERSRSKEKSKQLESKS 527



 Score = 40.4 bits (93), Expect = 0.020
 Identities = 66/333 (19%), Positives = 129/333 (38%), Gaps = 48/333 (14%)

Query: 1781 EISEASENIYSDVRGLSQNQQIPQN-SVTPRRGRRKKEVNQDILENTSSVEQELQITTGR 1839
            E++E  EN  S VR   +     +N S +P R   K++  +D    ++S E++++  + +
Sbjct: 387  ELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKD--HKSNSKERDIRRNSEK 444

Query: 1840 ESK-----RLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIK-----RSVENQESVEIIN 1889
            + K     + ++        +E +K + + S   +   +R++     R  EN +  E  +
Sbjct: 445  DDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQS 504

Query: 1890 DLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVR 1949
            D K       SR   K +     ++E+  +K  +K    Q R +     +G+    S  R
Sbjct: 505  DSKGKD-QERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563

Query: 1950 EDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRS 2009
            E S        V++          R R R         SK     R  + +     R R 
Sbjct: 564  ERSRSRDRSRRVRSR------THDRDRSR---------SKEYHRYREQEYRRRGRSRSRE 608

Query: 2010 TRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERT 2069
             R  P +S + D  +                      + +++ ESQS+ +  +   E ++
Sbjct: 609  RRTPPGRSRSKDRRR-----------------RRRDSRSSEREESQSRNKDKYRNQESKS 651

Query: 2070 DEMTHKETNEQEERLLATASFTKSSRSSRTRSS 2102
                 KE +E E+R+ + +    SS +SR + +
Sbjct: 652  SH--RKENSESEKRMYSKSRDHNSSNNSREKKA 682



 Score = 34.7 bits (78), Expect = 1.1
 Identities = 55/287 (19%), Positives = 108/287 (37%), Gaps = 17/287 (5%)

Query: 1774 KKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQEL 1833
            KK  K+K  S++ E   S  R    N+   +   +  +GR  + V +   ++ S      
Sbjct: 453  KKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSK----- 507

Query: 1834 QITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKV 1893
                G++ +R +S +  +    ++ + +   S    R  +   R  +  +     N    
Sbjct: 508  ----GKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTR 563

Query: 1894 STVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSN 1953
                S  R  R++RS   D  + + +K+  +  +++ R +   R R R   P   R    
Sbjct: 564  ERSRSRDRS-RRVRSRTHD-RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDR 621

Query: 1954 LESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNT 2013
                + +  +E + S    K     K    E   S   +   S K+  + S    S+ N+
Sbjct: 622  RRRRRDSRSSEREESQSRNK----DKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNS 677

Query: 2014 PAKSENVDVGKPALGKSILVPNEELSMVMSSK--KKLTKKTESQSQK 2058
              K  + D    +  K     NE  S ++ +K  +K+    E ++QK
Sbjct: 678  REKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQK 724


>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
            [Homo sapiens]
          Length = 1828

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 55/226 (24%), Positives = 94/226 (41%), Gaps = 29/226 (12%)

Query: 2041 VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR 2100
            +M +K K  ++  S     S HS SEE +   +  ++  ++     +   ++S+ SS + 
Sbjct: 1    MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60

Query: 2101 SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS 2160
             S+       SE  +E   S +  V  +AK K    PA  KE ++D+   +   P     
Sbjct: 61   ESQ-------SESESESAGSKSQPVLPEAKEK----PASKKERIADVKKMWEEYPDVYGV 109

Query: 2161 RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIR----TSKTKQASKNTEKESAWS---- 2212
            R+ N S +      +K++A S    G PK +  R      K KQ     E+E   S    
Sbjct: 110  RRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESE 169

Query: 2213 PPPIEIRLISPL---ASPADGVKSKPRKTTEVTGTGLGRNRKKLSS 2255
            P   +++   P+     P   VK +P+       T  G+ +K+ SS
Sbjct: 170  PEQKKVKARRPVPRRTVPKPRVKKQPK-------TQRGKRKKQDSS 208


>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
          Length = 1226

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 105/516 (20%), Positives = 199/516 (38%), Gaps = 88/516 (17%)

Query: 1703 NIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADV 1762
            N+ C  K     F+    ++ +   ++  + VV+ + +      +NV     ++E   ++
Sbjct: 381  NVKCAYKKYLYGFEEYCRSANIEFQMALPEKVVNKQCK----ECENVKEIKVKEENETEI 436

Query: 1763 ATPKMPGQS--VRKKTRKAKEISEASENIYSDVRGLSQN--QQIPQNSVTPRRGRRKKEV 1818
               KM  +   + ++ +  ++  E  ENI   + G  +N  + IP +S   +    KK  
Sbjct: 437  KEIKMEEERNIIPREEKPIEDEIERKENIKPSL-GSKKNLLESIPTHSDQEKEVNIKKPE 495

Query: 1819 NQDILEN----TSSVEQELQITTGRESKRLKSS--------QLLEPAVEETTK------- 1859
            + + L++    T+ V++ L I    E ++ KS         +++ PA +   K       
Sbjct: 496  DNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGYDEWIKADKIVRPADKNVPKIKHRKKI 555

Query: 1860 ---------KEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVSTV-TSPSRMIRKLRST 1909
                     K+ K S    +  R  K   +   S E+++ L ++    S +  I+ +  T
Sbjct: 556  KNKLDKEKDKDEKYSPKNCKLRRLSKPPFQTNPSPEMVSKLDLTDAKNSDTAHIKSIEIT 615

Query: 1910 N----LDASENT----------GNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSNLE 1955
            +    L ASE++          G +  D +  ++ +I H+   R   +S  +    S LE
Sbjct: 616  SILNGLQASESSAEDSEQEDERGAQDMDNNGKEESKIDHLTNNRNDLISKEEQNSSSLLE 675

Query: 1956 SSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPA 2015
             ++  V A+  +S    K   P ++    +V    + E+   ++ E    R+   ++T  
Sbjct: 676  ENK--VHADLVISKPVSKS--PERLRKDIEV----LSEDTDYEEDEVTKKRKDVKKDTTD 727

Query: 2016 KSENVDVGKPALGKSILVPNEELSMVMSSKKK--LTKKTESQSQKRSLHSVSEERTDEMT 2073
            KS    + +   GK      EE     S  KK    K  ES   + S +S S+E  +E  
Sbjct: 728  KSSKPQIKR---GKRRYCNTEECLKTGSPGKKEEKAKNKESLCMENSSNSSSDEDEEETK 784

Query: 2074 HKETN-------EQEERLLATASF------TKSSRSSRTRSSKAILLPDLSEPNNEPLFS 2120
             K T        E++ + L T  F          R     +S   L    ++   +   S
Sbjct: 785  AKMTPTKKYNGLEEKRKSLRTTGFYSGFSEVAEKRIKLLNNSDERLQNSRAKDRKDVWSS 844

Query: 2121 PASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPP 2156
               + P+K           LKEL SD  ++   SPP
Sbjct: 845  IQGQWPKKT----------LKELFSDSDTEAAASPP 870


>gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2
            [Homo sapiens]
          Length = 501

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 55/226 (24%), Positives = 94/226 (41%), Gaps = 29/226 (12%)

Query: 2041 VMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTR 2100
            +M +K K  ++  S     S HS SEE +   +  ++  ++     +   ++S+ SS + 
Sbjct: 1    MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESS 60

Query: 2101 SSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRS 2160
             S+       SE  +E   S +  V  +AK K    PA  KE ++D+   +   P     
Sbjct: 61   ESQ-------SESESESAGSKSQPVLPEAKEK----PASKKERIADVKKMWEEYPDVYGV 109

Query: 2161 RQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIR----TSKTKQASKNTEKESAWS---- 2212
            R+ N S +      +K++A S    G PK +  R      K KQ     E+E   S    
Sbjct: 110  RRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESE 169

Query: 2213 PPPIEIRLISPL---ASPADGVKSKPRKTTEVTGTGLGRNRKKLSS 2255
            P   +++   P+     P   VK +P+       T  G+ +K+ SS
Sbjct: 170  PEQKKVKARRPVPRRTVPKPRVKKQPK-------TQRGKRKKQDSS 208


>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
            polyclonal antibodies [Homo sapiens]
          Length = 1430

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 126/619 (20%), Positives = 217/619 (35%), Gaps = 66/619 (10%)

Query: 1613 VLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENL 1672
            +L + A   T++K     EN +     N      S Q ++K+D    + +     + E+ 
Sbjct: 121  LLDRFAQAVTKDKFALESENISEPYFTN--RRTISQQSAEKLDAACGIDKTENGTLFEDQ 178

Query: 1673 LDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVD 1732
             +V K+ ++   T      S  E  PL +  +           K +   ST  +    +D
Sbjct: 179  -NVDKEGKALPATGQKANVS-PEQPPLFTHTV-----------KDSDHISTRFLG--SMD 223

Query: 1733 DVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMP--GQSVRKKTRKAKEISEASE--- 1787
             + SS+  +    +  + +K A   + A +     P  G+   +K    K  S+  +   
Sbjct: 224  SLTSSEESSERPPLSTLTLKEADPSSKAAMRRKDSPPPGKVSSQKQPAEKATSDDKDSVS 283

Query: 1788 NIYSDVR-----GLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESK 1842
            NI ++++     G   +Q+ P    T         +  +I E   S     Q  +  +  
Sbjct: 284  NIATEIKEGPISGTVSSQKQPAEKATSDEKDSVSNIATEIKEGQQSGTVSPQKQSAWKVI 343

Query: 1843 RLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQE---SVEIINDLKVSTVTSP 1899
              K   LL  A   T   +    S  K+ P +      +     + EI + L+  TV+S 
Sbjct: 344  FKKKVSLLNIATRITGGGKSGTVSSQKQPPSKATSDKTDSALNIATEIKDGLQCGTVSSQ 403

Query: 1900 SRMIRKLRSTNLDASENT------GNKQDDKSSDKQLRIKHVRRVRGREVSPSDVREDSN 1953
             +   K  +   D+  N       G K    SS KQ  +K            +   EDS 
Sbjct: 404  KQPALKATTDEEDSVSNIATEIKDGEKSGTVSSQKQPALK-----------ATTDEEDSV 452

Query: 1954 LESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNT 2013
            L  +      E   +   +K+   +     ED  S    E +  +K    S R++     
Sbjct: 453  LNIATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIKDGEKSGTVSSRKK----- 507

Query: 2014 PAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMT 2073
            PA     D        +    + E+S  +SS+K    K  S  +   L    EE+  E +
Sbjct: 508  PALKATSDEKDSFSNITREKKDGEISRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKS 567

Query: 2074 HKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASE----VPRKA 2129
               ++EQ   L AT    K S  +  R  K          + +P     S+    VP  A
Sbjct: 568  RTVSSEQPPGLKATRD-EKDSLLNIARGKKYGEKTRRVSSHKQPALKATSDKENSVPNMA 626

Query: 2130 KAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELKDDAQSVETLGKPK 2189
               K E      ++   +SSQ     PAL++      + + +  E+KD  QS     + +
Sbjct: 627  TETKDE------QISGTVSSQ---KQPALKATSDKKDSVSNIPTEIKDGQQSGTVSSQKQ 677

Query: 2190 AKRIRTSKTKQASKNTEKE 2208
                 TS  K +  N   E
Sbjct: 678  LAWKATSVKKDSVSNIATE 696


>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
            sapiens]
          Length = 817

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 92/473 (19%), Positives = 170/473 (35%), Gaps = 53/473 (11%)

Query: 1716 KTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVK---SAQQEASADVATPKMPGQSV 1772
            K  +E S        ++D     +    Q  Q+ N K   S  ++    + +PK     +
Sbjct: 218  KETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKL 277

Query: 1773 RK-----KTRKAKEISEASENIYSDVRGLSQNQQIPQNSV-------TPRRGRRKKEVNQ 1820
            ++     K  + + +S  +  I SD   L    + P + V       T  +G R  E   
Sbjct: 278  KEISLACKITELESVSLPTPEIQSDF--LHSKVEAPPSEVADTLVIMTASKGVRLPEPKD 335

Query: 1821 DILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVE 1880
             ILE    + ++ +  T  E K+   S++ EP      K  ++ +     TP   K +++
Sbjct: 336  KILETPQKMTEKSESKTPGEGKKEDKSRMAEPM-----KGYMRPTKSRGLTPLLPKSTIQ 390

Query: 1881 NQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRG 1940
             QE  +    LK + +  P      +  T  D +    NK+   S +K+ +     +   
Sbjct: 391  EQERHK---QLKSAGIARPEEGRPVVSGTGNDIT-TPPNKELPPSPEKKTKPLATTQPAK 446

Query: 1941 REVSPSDVREDS-----------NLESSQLTVQAEFDMSAIPRK----RGRPRKINPSED 1985
               S +  +  S            L    +++ +    +A P++      RP  I PS+D
Sbjct: 447  TSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARP-SILPSKD 505

Query: 1986 VGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILV--PNEELSMVMS 2043
            V  K + + ++P+K+ +PS    +  +         V K     ++    P+      + 
Sbjct: 506  VKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLL 565

Query: 2044 SKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSK 2103
             KK    KTE +  +    +      D    K T+    +   T S T  +        K
Sbjct: 566  PKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK 625

Query: 2104 AILLPDLSEPNNEPLF-------SPASEVPRKAKAKKIEVPAQLKELVSDLSS 2149
            A  +P  S P+  P          P+S  PR ++         LK + S + S
Sbjct: 626  ATPMP--SRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGS 676


>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sapiens]
          Length = 887

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 92/473 (19%), Positives = 170/473 (35%), Gaps = 53/473 (11%)

Query: 1716 KTAQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVK---SAQQEASADVATPKMPGQSV 1772
            K  +E S        ++D     +    Q  Q+ N K   S  ++    + +PK     +
Sbjct: 218  KETKEGSVAVQIPDLLEDKAQKLSFCEDQNAQDRNSKGSDSLNKKVDLTLLSPKSENDKL 277

Query: 1773 RK-----KTRKAKEISEASENIYSDVRGLSQNQQIPQNSV-------TPRRGRRKKEVNQ 1820
            ++     K  + + +S  +  I SD   L    + P + V       T  +G R  E   
Sbjct: 278  KEISLACKITELESVSLPTPEIQSDF--LHSKVEAPPSEVADTLVIMTASKGVRLPEPKD 335

Query: 1821 DILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVE 1880
             ILE    + ++ +  T  E K+   S++ EP      K  ++ +     TP   K +++
Sbjct: 336  KILETPQKMTEKSESKTPGEGKKEDKSRMAEPM-----KGYMRPTKSRGLTPLLPKSTIQ 390

Query: 1881 NQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRG 1940
             QE  +    LK + +  P      +  T  D +    NK+   S +K+ +     +   
Sbjct: 391  EQERHK---QLKSAGIARPEEGRPVVSGTGNDIT-TPPNKELPPSPEKKTKPLATTQPAK 446

Query: 1941 REVSPSDVREDS-----------NLESSQLTVQAEFDMSAIPRK----RGRPRKINPSED 1985
               S +  +  S            L    +++ +    +A P++      RP  I PS+D
Sbjct: 447  TSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARP-SILPSKD 505

Query: 1986 VGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILV--PNEELSMVMS 2043
            V  K + + ++P+K+ +PS    +  +         V K     ++    P+      + 
Sbjct: 506  VKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLL 565

Query: 2044 SKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSK 2103
             KK    KTE +  +    +      D    K T+    +   T S T  +        K
Sbjct: 566  PKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK 625

Query: 2104 AILLPDLSEPNNEPLF-------SPASEVPRKAKAKKIEVPAQLKELVSDLSS 2149
            A  +P  S P+  P          P+S  PR ++         LK + S + S
Sbjct: 626  ATPMP--SRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGS 676


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 103/511 (20%), Positives = 182/511 (35%), Gaps = 117/511 (22%)

Query: 1814 RKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPR 1873
            RKKE+++D  E     E+++Q     + K     ++ E   E+  KK      + K+   
Sbjct: 139  RKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREK--EKPEKKATHKEKIEKKEKP 196

Query: 1874 RIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIK 1933
              K   + Q+        K  T        +K         E  G KQ+ K      ++K
Sbjct: 197  ETKTLAKEQK--------KAKTAEKSEEKTKK---------EVKGGKQE-KVKQTAAKVK 238

Query: 1934 HVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPR--------------------- 1972
             V++      +PS  +E  + E + ++   + D  A  R                     
Sbjct: 239  EVQK------TPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPP 292

Query: 1973 -----KRGRPRKINPS--EDVGSKAVKEER---SPKKKEAPSIRRRSTRNTPAKSENVDV 2022
                 +  RP   +P+  E  G K   E++     KKKE   I+++S + T      +DV
Sbjct: 293  PLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETA-----IDV 347

Query: 2023 GKPALGKSILVPNEELSMVMSS------KKKLTKKTESQSQKRSLHSVSEER-------- 2068
             K   GK+       + +   +      KK+ +KKT+  ++        +E+        
Sbjct: 348  EKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPA 407

Query: 2069 ----------TDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPL 2118
                      +D+    +T   +E + A +           +++K +      E + +  
Sbjct: 408  KSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTS 467

Query: 2119 FSPASEVPRKAKAKKIEVPAQLK---------ELVSDLSSQFVISPPALRSRQKNTSNKN 2169
                 + P K K +K  VPA LK         E +S    +    PP L+ ++     + 
Sbjct: 468  SILKDKEPIKGKEEK--VPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKK-----EE 520

Query: 2170 KLEDELKDDAQSV--ETLGKPKAKRIRTSKTKQASKNTEK----------ESAWSPPP-- 2215
            K E ++K +A+    E +   K   ++  KT    K  EK          E    P P  
Sbjct: 521  KPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTK 580

Query: 2216 -IEIRLISPLASPADGVKSKPRKTTEVTGTG 2245
              E R   P +   D  K  P+ T+EVT +G
Sbjct: 581  KAEHREREPPSIKTDKPKPTPKGTSEVTESG 611



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 77/397 (19%), Positives = 153/397 (38%), Gaps = 41/397 (10%)

Query: 1636 GQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHE 1695
            GQ   +P  + ++Q S+        P P   A+ E   +  K    K++TS+T ++   E
Sbjct: 285  GQSPAIPPPLPTEQASR--------PTPASPALEEK--EGEKKKAEKKVTSETKKKE-KE 333

Query: 1696 TIPLVSQN---IMCPTKLVKSAFKTAQETSTMTMNVSQVDDVV---SSKTRTRGQRIQNV 1749
             I   S+    I    K    A +T Q T  +    +   D     S KT+   +  Q  
Sbjct: 334  DIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPK 393

Query: 1750 NVKSAQQEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTP 1809
              K  ++E   + A       SV       K++   +E    ++  +S  + +P      
Sbjct: 394  GKKQEKKEKHVEPAKSPKKEHSVPSD----KQVKAKTERAKEEIGAVSIKKAVPGKKEEK 449

Query: 1810 RRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTK 1869
                 ++E+ ++    TSS+ ++ +   G+E K   S +  EP     TKK+ K+S   K
Sbjct: 450  TTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEP----ETKKDEKMSKAGK 505

Query: 1870 RT---PRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDD--- 1923
                 P +++   E +   +I  + K     S    I K      + + + G  ++    
Sbjct: 506  EVKPKPPQLQGKKEEKPEPQIKKEAK--PAISEKVQIHKQDIVKPEKTVSHGKPEEKVLK 563

Query: 1924 ----KSSDKQLRIKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRK 1979
                 + +K  + K  ++   RE  P  ++ D      + T +   +++   +K+    +
Sbjct: 564  QVKAVTIEKTAKPKPTKKAEHREREPPSIKTD----KPKPTPKGTSEVTESGKKKTEISE 619

Query: 1980 INPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAK 2016
                E    K ++EE+   +KE+  +   +    PA+
Sbjct: 620  KESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPAR 656


>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
            protein [Homo sapiens]
          Length = 1463

 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 100/528 (18%), Positives = 197/528 (37%), Gaps = 90/528 (17%)

Query: 1618 ANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPI--KVAIAENLLDV 1675
            AN  TEE++   G + +     +LP  V  + + +K++        +  +  I+EN+L+ 
Sbjct: 462  ANYDTEERV---GSSSSESCAQDLPVLVGEEGEVKKLENTGIEANVLCLESEISENILEK 518

Query: 1676 IKDTRSKEITSDTMEQSIHET-IPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQ-VDD 1733
              D   K+     + QS  +T +  V      PT L   + K  Q  S    ++S+ V+ 
Sbjct: 519  GGDPLEKQDQISGLSQSEVKTDVCTVHLPNDFPTCLTSES-KVYQPVSCPLSDLSENVES 577

Query: 1734 VVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPG------QSVRKKTRKAKEISEASE 1787
            VV+ +  T    ++    K    +    + +PK+        Q+V +++ K+ E+     
Sbjct: 578  VVNEEKITESSLVEITEHKDFTLKTEELIESPKLESSEGEIIQTVDRQSVKSPEVQLLGH 637

Query: 1788 NIYSDVRGL----------------SQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVE- 1830
                DV  +                S+N  +  N +  +  +  +E N+ + E+  S E 
Sbjct: 638  VETEDVEIIATCDTFGNEDFNNIQDSENNLLKNNLLNTKLEKSLEEKNESLTEHPRSTEL 697

Query: 1831 -----QELQITTGRESKRLKSSQLLEPAVEETTKKEVKVS---SVTKRTPRRIKRSVENQ 1882
                 +++Q     ++  +   +  +    +  + EV+ S    + +     +    EN 
Sbjct: 698  PKTHIEQIQKHFSEDNNEMIPMEC-DSFCSDQNESEVEPSVNADLKQMNENSVTHCSENN 756

Query: 1883 ESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRVRGRE 1942
                 + D KV TV+ PS                      +   D   + K  R  R R 
Sbjct: 757  MPSSDLADEKVETVSQPS----------------------ESPKDTIDKTKKPRTRRSRF 794

Query: 1943 VSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEA 2002
             SPS     +                  P+++ RP+  +P  + G ++ K +    K E+
Sbjct: 795  HSPSTTWSPNK---------------DTPQEKKRPQSPSPRRETGKESRKSQSPSPKNES 839

Query: 2003 PSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTE-SQSQKRSL 2061
               R++S   +P K    D+ +         P  + +      + L+ + E S+  KRS 
Sbjct: 840  ARGRKKSRSQSPKK----DIARERRQSQSRSPKRDTTRESRRSESLSPRRETSRENKRSQ 895

Query: 2062 HSVSEERTDEMTHKETNEQE--------ERLLATASFTKSSRSSRTRS 2101
              V +    E +  ++ E+E        ER   T  +++S   SR+ S
Sbjct: 896  PRVKDSSPGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPS 943


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
            sapiens]
          Length = 916

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 60/323 (18%), Positives = 124/323 (38%), Gaps = 33/323 (10%)

Query: 1950 EDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRS 2009
            E S +E +   +  E  +S    K+    +     +   + V  ++SP K  AP ++   
Sbjct: 465  EKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE 524

Query: 2010 TRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSE-ER 2068
                  + +  +  +    KS     ++     S K+  ++K E + ++    + +E E 
Sbjct: 525  GEKEEEEGQEEEEEEDEGAKS-----DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 579

Query: 2069 TDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRK 2128
             +    K+  E+ E +         ++  +   +K+   P    P  E   SP  + P +
Sbjct: 580  AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKS---PVPKSPVEEKGKSPVPKSPVE 636

Query: 2129 AKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELK--------DDAQ 2180
             K K   VP   K  V +     V   P +  + K+  +K+ +E++ K        ++A+
Sbjct: 637  EKGKS-PVP---KSPVEEKGKSPVPKSP-VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 691

Query: 2181 SVETLGKPKAKRIRTSKTKQASKNTEKESAWSPP-----------PIEIRLISPLASPAD 2229
            S   +GK + K     + K+A K  + E     P           P++   ++ + +   
Sbjct: 692  SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 751

Query: 2230 GVKSKPRKTTEVTGTGLGRNRKK 2252
             VK    K T+  G  L + ++K
Sbjct: 752  SVKVHLEKETKEEGKPLQQEKEK 774



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 79/438 (18%), Positives = 153/438 (34%), Gaps = 54/438 (12%)

Query: 1816 KEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEE----TTKKEVKVSSVTKRT 1871
            ++   ++ E  +++ +EL ++   E K     +  EP  EE      K  VK ++   + 
Sbjct: 463  EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 522

Query: 1872 PRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLR 1931
                K   E QE  E                  +      D +E  G++++  S  ++  
Sbjct: 523  EEGEKEEEEGQEEEE-----------------EEDEGAKSDQAEEGGSEKEGSSEKEEGE 565

Query: 1932 IKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSA-----IPRKRGRPRKINPSEDV 1986
             +        E   ++ +E+  +E     V  + ++ A      P K   P   +P E+ 
Sbjct: 566  QEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEK 625

Query: 1987 GSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKK 2046
            G   V +    +K ++P            KS   + GK  + KS   P EE      SK 
Sbjct: 626  GKSPVPKSPVEEKGKSP----------VPKSPVEEKGKSPVPKS---PVEEKGKSPVSKS 672

Query: 2047 KLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAIL 2106
             + +K +S   K  +     +   E+   E  E+EE+ +  A           +  K   
Sbjct: 673  PVEEKAKSPVPKSPVEEAKSKA--EVGKGEQKEEEEKEVKEA---PKEEKVEKKEEKPKD 727

Query: 2107 LPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTS 2166
            +P+  +  +       +EV    K+ K+ +  + KE    L  +            +   
Sbjct: 728  VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEG 787

Query: 2167 NKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLAS 2226
            +    +   K+D   +   G+ + K     +TK+     E+E       +++       S
Sbjct: 788  SDKGAKGSRKED---IAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDL-------S 837

Query: 2227 PADGVKSKPRKTTEVTGT 2244
            PAD  K   +   +V  T
Sbjct: 838  PADEKKGGDKSEEKVVVT 855



 Score = 40.8 bits (94), Expect = 0.015
 Identities = 92/472 (19%), Positives = 167/472 (35%), Gaps = 97/472 (20%)

Query: 1478 LNQEVALNLKEDHEVEVGVLKESVDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEA 1537
            + +E+A+++KE+ +      +E  +  EE++    SP       V E+E  + ++ G+E 
Sbjct: 476  ITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQE- 534

Query: 1538 RNLSFNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILE 1597
                                   +++  D     D AE   +E +G             E
Sbjct: 535  -----------------------EEEEEDEGAKSDQAEEGGSEKEGS-----------SE 560

Query: 1598 GEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTL 1657
             EEGE E G+  +     +A   A EEK V     +   ++A     V +D K +K    
Sbjct: 561  KEEGEQEEGETEAEAEGEEA--EAKEEKKV----EEKSEEVATKEELV-ADAKVEK---- 609

Query: 1658 PYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKT 1717
               PE  K  + ++    +++     +    +E+     +P                   
Sbjct: 610  ---PEKAKSPVPKS---PVEEKGKSPVPKSPVEEKGKSPVPK----------------SP 647

Query: 1718 AQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTR 1777
             +E     +  S V++   S             V  +  E  A    PK P +  + K  
Sbjct: 648  VEEKGKSPVPKSPVEEKGKSP------------VSKSPVEEKAKSPVPKSPVEEAKSKAE 695

Query: 1778 KAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILEN--------TSSV 1829
              K   E  E    +V+   + +++ +    P+    KK+    + E         T SV
Sbjct: 696  VGK--GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSV 753

Query: 1830 EQELQITTGRESKRLKSSQLLEPAVEETTKKEV---KVSSVTKRTPRRIKRSVENQESVE 1886
            +  L+  T  E K L+  +  E A  E   +E    K +  +++    +   VE +E VE
Sbjct: 754  KVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE 813

Query: 1887 IINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRV 1938
                 K S       ++    +  LD S     K  DKS +K +  K V ++
Sbjct: 814  QETKEKGSGREEEKGVV----TNGLDLSPADEKKGGDKSEEKVVVTKTVEKI 861


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
            sapiens]
          Length = 540

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 60/323 (18%), Positives = 124/323 (38%), Gaps = 33/323 (10%)

Query: 1950 EDSNLESSQLTVQAEFDMSAIPRKRGRPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRS 2009
            E S +E +   +  E  +S    K+    +     +   + V  ++SP K  AP ++   
Sbjct: 89   EKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE 148

Query: 2010 TRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSE-ER 2068
                  + +  +  +    KS     ++     S K+  ++K E + ++    + +E E 
Sbjct: 149  GEKEEEEGQEEEEEEDEGAKS-----DQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEE 203

Query: 2069 TDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRK 2128
             +    K+  E+ E +         ++  +   +K+   P    P  E   SP  + P +
Sbjct: 204  AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKS---PVPKSPVEEKGKSPVPKSPVE 260

Query: 2129 AKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTSNKNKLEDELK--------DDAQ 2180
             K K   VP   K  V +     V   P +  + K+  +K+ +E++ K        ++A+
Sbjct: 261  EKGKS-PVP---KSPVEEKGKSPVPKSP-VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 315

Query: 2181 SVETLGKPKAKRIRTSKTKQASKNTEKESAWSPP-----------PIEIRLISPLASPAD 2229
            S   +GK + K     + K+A K  + E     P           P++   ++ + +   
Sbjct: 316  SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 375

Query: 2230 GVKSKPRKTTEVTGTGLGRNRKK 2252
             VK    K T+  G  L + ++K
Sbjct: 376  SVKVHLEKETKEEGKPLQQEKEK 398



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 79/438 (18%), Positives = 153/438 (34%), Gaps = 54/438 (12%)

Query: 1816 KEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEE----TTKKEVKVSSVTKRT 1871
            ++   ++ E  +++ +EL ++   E K     +  EP  EE      K  VK ++   + 
Sbjct: 87   EDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKE 146

Query: 1872 PRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLR 1931
                K   E QE  E                  +      D +E  G++++  S  ++  
Sbjct: 147  EEGEKEEEEGQEEEE-----------------EEDEGAKSDQAEEGGSEKEGSSEKEEGE 189

Query: 1932 IKHVRRVRGREVSPSDVREDSNLESSQLTVQAEFDMSA-----IPRKRGRPRKINPSEDV 1986
             +        E   ++ +E+  +E     V  + ++ A      P K   P   +P E+ 
Sbjct: 190  QEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEK 249

Query: 1987 GSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGKPALGKSILVPNEELSMVMSSKK 2046
            G   V +    +K ++P            KS   + GK  + KS   P EE      SK 
Sbjct: 250  GKSPVPKSPVEEKGKSP----------VPKSPVEEKGKSPVPKS---PVEEKGKSPVSKS 296

Query: 2047 KLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSRSSRTRSSKAIL 2106
             + +K +S   K  +     +   E+   E  E+EE+ +  A           +  K   
Sbjct: 297  PVEEKAKSPVPKSPVEEAKSKA--EVGKGEQKEEEEKEVKEA---PKEEKVEKKEEKPKD 351

Query: 2107 LPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISPPALRSRQKNTS 2166
            +P+  +  +       +EV    K+ K+ +  + KE    L  +            +   
Sbjct: 352  VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEG 411

Query: 2167 NKNKLEDELKDDAQSVETLGKPKAKRIRTSKTKQASKNTEKESAWSPPPIEIRLISPLAS 2226
            +    +   K+D   +   G+ + K     +TK+     E+E       +++       S
Sbjct: 412  SDKGAKGSRKED---IAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDL-------S 461

Query: 2227 PADGVKSKPRKTTEVTGT 2244
            PAD  K   +   +V  T
Sbjct: 462  PADEKKGGDKSEEKVVVT 479



 Score = 40.8 bits (94), Expect = 0.015
 Identities = 92/472 (19%), Positives = 167/472 (35%), Gaps = 97/472 (20%)

Query: 1478 LNQEVALNLKEDHEVEVGVLKESVDLPEEKLPISDSPPDTQEIHVIEQEKLEAQDSGEEA 1537
            + +E+A+++KE+ +      +E  +  EE++    SP       V E+E  + ++ G+E 
Sbjct: 100  ITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQE- 158

Query: 1538 RNLSFNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAEVDGELFVAQSNFTLILE 1597
                                   +++  D     D AE   +E +G             E
Sbjct: 159  -----------------------EEEEEDEGAKSDQAEEGGSEKEGS-----------SE 184

Query: 1598 GEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTL 1657
             EEGE E G+  +     +A   A EEK V     +   ++A     V +D K +K    
Sbjct: 185  KEEGEQEEGETEAEAEGEEA--EAKEEKKV----EEKSEEVATKEELV-ADAKVEK---- 233

Query: 1658 PYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPLVSQNIMCPTKLVKSAFKT 1717
               PE  K  + ++    +++     +    +E+     +P                   
Sbjct: 234  ---PEKAKSPVPKS---PVEEKGKSPVPKSPVEEKGKSPVPK----------------SP 271

Query: 1718 AQETSTMTMNVSQVDDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMPGQSVRKKTR 1777
             +E     +  S V++   S             V  +  E  A    PK P +  + K  
Sbjct: 272  VEEKGKSPVPKSPVEEKGKSP------------VSKSPVEEKAKSPVPKSPVEEAKSKAE 319

Query: 1778 KAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILEN--------TSSV 1829
              K   E  E    +V+   + +++ +    P+    KK+    + E         T SV
Sbjct: 320  VGK--GEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSV 377

Query: 1830 EQELQITTGRESKRLKSSQLLEPAVEETTKKEV---KVSSVTKRTPRRIKRSVENQESVE 1886
            +  L+  T  E K L+  +  E A  E   +E    K +  +++    +   VE +E VE
Sbjct: 378  KVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE 437

Query: 1887 IINDLKVSTVTSPSRMIRKLRSTNLDASENTGNKQDDKSSDKQLRIKHVRRV 1938
                 K S       ++    +  LD S     K  DKS +K +  K V ++
Sbjct: 438  QETKEKGSGREEEKGVV----TNGLDLSPADEKKGGDKSEEKVVVTKTVEKI 485


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 130/759 (17%), Positives = 299/759 (39%), Gaps = 73/759 (9%)

Query: 1473 VSERRLNQEVALNLKEDHEVEVGVLKESVDLPEEKLPISDSPPDTQEIHVIEQEKLEAQD 1532
            + E +  QE +LN+KE       ++ E      E+    DS     EI ++   K   Q+
Sbjct: 1379 IQESQSKQEQSLNMKEKDNETTKIVSEM-----EQFKPKDSALLRIEIEMLGLSK-RLQE 1432

Query: 1533 SGEEARNLS--------FNELYPSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAEVDGE 1584
            S +E ++++          E+  S + +L+ N   I  +  +  +    A C + E +  
Sbjct: 1433 SHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEET 1492

Query: 1585 LFVAQSNFTLILEGEEGEVEPGDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSA 1644
            +   + N +   E E   ++    A +D L        E++     E  N  QI+ +   
Sbjct: 1493 INELRVNLSE-KETEISTIQKQLEAINDKLQNKIQEIYEKE-----EQFNIKQISEVQEK 1546

Query: 1645 VTS-----DQKSQKVDTLPYVPEPIKVAIAENLLDVIKDTRSKEITSDTMEQSIHETIPL 1699
            V       + +  K   L  +    K+    N L   ++     I      + + E + +
Sbjct: 1547 VNELKQFKEHRKAKDSALQSIES--KMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQI 1604

Query: 1700 VSQNIMCPTKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQR----IQNVNVKSAQ 1755
                +   TK + +  K +QE     + ++ V++           +     Q +N+++ +
Sbjct: 1605 ERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIE 1664

Query: 1756 QEASADVATPKMPGQSVRKKTRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRK 1815
             E            + +R  T++  ++    E +  +   L +N +      T  R   K
Sbjct: 1665 TENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLR-----ETITRDLEK 1719

Query: 1816 KE----VNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRT 1871
            +E    V+  + E+  ++++   I + + ++     + LE + +    +++K+    +  
Sbjct: 1720 QEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIA 1779

Query: 1872 PRRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTN---------LDASEN---TGN 1919
               +K   E QE+++ +  +        S M + L ++N         L A+E+   T  
Sbjct: 1780 HMHLK---EQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLK 1836

Query: 1920 KQDDKSSDKQLRIKHVRR-VRGREVSPSDVREDSNLESSQLTVQAEFDMSAIPRKRGRPR 1978
            K  +++  K   ++ +++ ++ + ++ S + E  NL  +Q   +   +M ++ ++R   R
Sbjct: 1837 KDVNETQKKVSEMEQLKKQIKDQSLTLSKL-EIENLNLAQKLHENLEEMKSVMKERDNLR 1895

Query: 1979 KINPSEDVGSKAVKEERSPKKKEAPSIRRR-STRNTPAKS--ENVDVGKPALGKSILVPN 2035
            ++  +  +    +KE     K     I++   T    +K   E VD  +  + +  +  +
Sbjct: 1896 RVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQIS 1955

Query: 2036 EELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFTKSSR 2095
            +    +  SK +L KK + + QK+ L  +  +    M+HK+ NE E+         K   
Sbjct: 1956 DIQKDLDKSKDELQKKIQ-ELQKKELQLLRVKEDVNMSHKKINEMEQ--------LKKQF 2006

Query: 2096 SSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSSQFVISP 2155
             ++  S +++ + +      + L     E+  +  AK+ +   ++KE +     QF+ + 
Sbjct: 2007 EAQNLSMQSVRMDNFQ--LTKKLHESLEEI--RIVAKERDELRRIKESLKMERDQFIATL 2062

Query: 2156 PALRSRQKNTSNKNKLEDELKDDAQSVETLGKPKAKRIR 2194
              + +R +        +  L D  Q +    + K  RI+
Sbjct: 2063 REMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIK 2101



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 129/712 (18%), Positives = 283/712 (39%), Gaps = 83/712 (11%)

Query: 1290 EMDEGSQSLEKLDVSKG--NSSVS------ITSDETTLEYQ-DAPSPEDLEETVFTASKP 1340
            E D+ +Q LE+ D+ +   N  +       +TS   TL+ +  A     +   +   +K 
Sbjct: 372  EKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKM 431

Query: 1341 KSSSTA----LTTNVTEQTEK-------DGDKDVFASEVTPSDLQKQMGNLEDAETKDLL 1389
            K+S+ A    + TN+T +T K       + D+ V +     S+    +  +E      LL
Sbjct: 432  KNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLL 491

Query: 1390 VAAEAFSELNHLSPVQGTEASLCAPSVYEGKIFTQKSKVPVLDEGLTSVETYTPAIRAND 1449
                  SELN L   +    +L     YE ++ T+K ++ +  +    ++ +    R   
Sbjct: 492  NQENIESELNSL---RADYDNLVLD--YE-QLRTEKEEMELKLKEKNDLDEFEALERKTK 545

Query: 1450 NKSMADVLGDGGNSSLTISEGPIVSERRLNQ-EVALNLKEDHEVEVGVLKESVD---LPE 1505
                  ++ +  N    +    + ++   N+    + L  + E ++  L+E +D   L  
Sbjct: 546  KDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLEN 605

Query: 1506 EKLPISDSPPDTQEIHVIEQEKLEAQDSGEEARNLSFNELYPSGTLKLQYNFDTIDQQFC 1565
             K+ +S S    ++   ++Q   +A+    +A+  S      S  L+L+     +   + 
Sbjct: 606  IKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRES--AFLRSENLELKEKMKELATTYK 663

Query: 1566 DLADNKDTAECDI-------AEVDGELFVAQSNFTLILEGEEGEVEPGDFASSDV----- 1613
             + ++    +  +        +++ EL  A +  T +    +G+V      + ++     
Sbjct: 664  QMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKIT 723

Query: 1614 -LPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIKVAIAENL 1672
             L K  N   EE      E     ++ +LPS V   +K  +  +     E + +  +E  
Sbjct: 724  DLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKS-----EELHIITSE-- 776

Query: 1673 LDVIKDTRSKEIT-SDTMEQSIHETIPLVSQNIMCPTKLVKSAFKTAQETSTMTMNVSQV 1731
                KD    E+   ++  Q + E I     ++       KS  +  Q   T+ M+  Q 
Sbjct: 777  ----KDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQK 832

Query: 1732 DDVVSSKTRTRGQRIQNVNVKSAQQEASADVATPKMP--GQSVRKKTRKAKEISEASENI 1789
              +V  +     Q I N++ ++ + ++S      ++    Q +++KTR+ +E     E +
Sbjct: 833  YKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQL 892

Query: 1790 YSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQL 1849
               +    +N+     +V   +    +++ Q + E  +  +++  +   +ES +++  QL
Sbjct: 893  KEQL----ENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQL 948

Query: 1850 LEPAVEETTKKEVKVSSVTKRTPRRIKRSVEN-QESVEIINDLKVSTVTSPSRMIRKLRS 1908
             +  + +T    +        T  +++ ++E+ ++  E IN LK       SR       
Sbjct: 949  -KSDIHDTVNMNID-------TQEQLRNALESLKQHQETINTLKSKISEEVSR------- 993

Query: 1909 TNLDASENTGNKQDDKSSDKQLRI--KHVRRVRGREVSPSDVREDSNLESSQ 1958
             NL   ENTG  +D+    K + I  K     +  +   +DV+++  +E  +
Sbjct: 994  -NLHMEENTGETKDE-FQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQR 1043


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%)

Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765
            +K    A KTAQ   ++     Q + V  ++ R   +R   Q    + A++EA  ++   
Sbjct: 1580 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1634

Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812
            ++      +   +A+E+++      ++              RG ++ Q + Q  +  +  
Sbjct: 1635 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1694

Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872
             +++++ +   +   + EQEL        +  +  QLLE   EE  + + + ++ T+   
Sbjct: 1695 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1748

Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928
               KR     E  ++  +++V  + S +R   + RST+  + +      G  ++      
Sbjct: 1749 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804

Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975
            +LR       R R+++  D  R+ +              E+++L  +AE  +     +  
Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1864

Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031
            R R++   E    + ++E+ +  K +   I  R  +   A    ++  K      L +  
Sbjct: 1865 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1921

Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091
             V  E L++  S +K    K E + +   + S +E+        E     +R LA A   
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1980

Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150
            +  R +  R  K++   + +    +     A E   + KA K+E   +L+E     S+ Q
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2035

Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200
              ++  A + R +     +     + E EL+   Q  +++     G+ +A R    + ++
Sbjct: 2036 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2095

Query: 2201 ASKNTEKESAWSPPPIE 2217
            A    E+E+A S   +E
Sbjct: 2096 ARVQAEREAAQSRRQVE 2112


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%)

Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765
            +K    A KTAQ   ++     Q + V  ++ R   +R   Q    + A++EA  ++   
Sbjct: 1584 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1638

Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812
            ++      +   +A+E+++      ++              RG ++ Q + Q  +  +  
Sbjct: 1639 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1698

Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872
             +++++ +   +   + EQEL        +  +  QLLE   EE  + + + ++ T+   
Sbjct: 1699 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1752

Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928
               KR     E  ++  +++V  + S +R   + RST+  + +      G  ++      
Sbjct: 1753 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1808

Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975
            +LR       R R+++  D  R+ +              E+++L  +AE  +     +  
Sbjct: 1809 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1868

Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031
            R R++   E    + ++E+ +  K +   I  R  +   A    ++  K      L +  
Sbjct: 1869 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1925

Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091
             V  E L++  S +K    K E + +   + S +E+        E     +R LA A   
Sbjct: 1926 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1984

Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150
            +  R +  R  K++   + +    +     A E   + KA K+E   +L+E     S+ Q
Sbjct: 1985 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2039

Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200
              ++  A + R +     +     + E EL+   Q  +++     G+ +A R    + ++
Sbjct: 2040 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2099

Query: 2201 ASKNTEKESAWSPPPIE 2217
            A    E+E+A S   +E
Sbjct: 2100 ARVQAEREAAQSRRQVE 2116


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%)

Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765
            +K    A KTAQ   ++     Q + V  ++ R   +R   Q    + A++EA  ++   
Sbjct: 1580 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1634

Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812
            ++      +   +A+E+++      ++              RG ++ Q + Q  +  +  
Sbjct: 1635 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1694

Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872
             +++++ +   +   + EQEL        +  +  QLLE   EE  + + + ++ T+   
Sbjct: 1695 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1748

Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928
               KR     E  ++  +++V  + S +R   + RST+  + +      G  ++      
Sbjct: 1749 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804

Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975
            +LR       R R+++  D  R+ +              E+++L  +AE  +     +  
Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1864

Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031
            R R++   E    + ++E+ +  K +   I  R  +   A    ++  K      L +  
Sbjct: 1865 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1921

Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091
             V  E L++  S +K    K E + +   + S +E+        E     +R LA A   
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1980

Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150
            +  R +  R  K++   + +    +     A E   + KA K+E   +L+E     S+ Q
Sbjct: 1981 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2035

Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200
              ++  A + R +     +     + E EL+   Q  +++     G+ +A R    + ++
Sbjct: 2036 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2095

Query: 2201 ASKNTEKESAWSPPPIE 2217
            A    E+E+A S   +E
Sbjct: 2096 ARVQAEREAAQSRRQVE 2112


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%)

Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765
            +K    A KTAQ   ++     Q + V  ++ R   +R   Q    + A++EA  ++   
Sbjct: 1548 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1602

Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812
            ++      +   +A+E+++      ++              RG ++ Q + Q  +  +  
Sbjct: 1603 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1662

Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872
             +++++ +   +   + EQEL        +  +  QLLE   EE  + + + ++ T+   
Sbjct: 1663 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1716

Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928
               KR     E  ++  +++V  + S +R   + RST+  + +      G  ++      
Sbjct: 1717 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1772

Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975
            +LR       R R+++  D  R+ +              E+++L  +AE  +     +  
Sbjct: 1773 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1832

Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031
            R R++   E    + ++E+ +  K +   I  R  +   A    ++  K      L +  
Sbjct: 1833 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1889

Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091
             V  E L++  S +K    K E + +   + S +E+        E     +R LA A   
Sbjct: 1890 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1948

Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150
            +  R +  R  K++   + +    +     A E   + KA K+E   +L+E     S+ Q
Sbjct: 1949 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2003

Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200
              ++  A + R +     +     + E EL+   Q  +++     G+ +A R    + ++
Sbjct: 2004 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2063

Query: 2201 ASKNTEKESAWSPPPIE 2217
            A    E+E+A S   +E
Sbjct: 2064 ARVQAEREAAQSRRQVE 2080


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%)

Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765
            +K    A KTAQ   ++     Q + V  ++ R   +R   Q    + A++EA  ++   
Sbjct: 1717 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1771

Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812
            ++      +   +A+E+++      ++              RG ++ Q + Q  +  +  
Sbjct: 1772 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1831

Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872
             +++++ +   +   + EQEL        +  +  QLLE   EE  + + + ++ T+   
Sbjct: 1832 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1885

Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928
               KR     E  ++  +++V  + S +R   + RST+  + +      G  ++      
Sbjct: 1886 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1941

Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975
            +LR       R R+++  D  R+ +              E+++L  +AE  +     +  
Sbjct: 1942 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 2001

Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031
            R R++   E    + ++E+ +  K +   I  R  +   A    ++  K      L +  
Sbjct: 2002 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 2058

Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091
             V  E L++  S +K    K E + +   + S +E+        E     +R LA A   
Sbjct: 2059 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 2117

Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150
            +  R +  R  K++   + +    +     A E   + KA K+E   +L+E     S+ Q
Sbjct: 2118 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2172

Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200
              ++  A + R +     +     + E EL+   Q  +++     G+ +A R    + ++
Sbjct: 2173 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2232

Query: 2201 ASKNTEKESAWSPPPIE 2217
            A    E+E+A S   +E
Sbjct: 2233 ARVQAEREAAQSRRQVE 2249


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 103/557 (18%), Positives = 222/557 (39%), Gaps = 71/557 (12%)

Query: 1708 TKLVKSAFKTAQETSTMTMNVSQVDDVVSSKTRTRGQRI--QNVNVKSAQQEASADVATP 1765
            +K    A KTAQ   ++     Q + V  ++ R   +R   Q    + A++EA  ++   
Sbjct: 1558 SKRASFAEKTAQLERSL-----QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1612

Query: 1766 KMPGQSVRKKTRKAKEISEASENIYSDV-------------RGLSQNQQIPQNSVTPRRG 1812
            ++      +   +A+E+++      ++              RG ++ Q + Q  +  +  
Sbjct: 1613 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQEL 1672

Query: 1813 RRKKEVNQDILENTSSVEQELQITTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTP 1872
             +++++ +   +   + EQEL        +  +  QLLE   EE  + + + ++ T+   
Sbjct: 1673 EKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLE---EELARLQREAAAATQ--- 1726

Query: 1873 RRIKRSVENQESVEIINDLKVSTVTSPSRMIRKLRSTNLDASE----NTGNKQDDKSSDK 1928
               KR     E  ++  +++V  + S +R   + RST+  + +      G  ++      
Sbjct: 1727 ---KRQELEAELAKVRAEMEV-LLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1782

Query: 1929 QLRIKHVRRVRGREVSPSD-VREDSNL------------ESSQLTVQAEFDMSAIPRKRG 1975
            +LR       R R+++  D  R+ +              E+++L  +AE  +     +  
Sbjct: 1783 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1842

Query: 1976 RPRKINPSEDVGSKAVKEERSPKKKEAPSIRRRSTRNTPAKSENVDVGK----PALGKSI 2031
            R R++   E    + ++E+ +  K +   I  R  +   A    ++  K      L +  
Sbjct: 1843 RLRRLAEDEAFQRRRLEEQAAQHKAD---IEERLAQLRKASDSELERQKGLVEDTLRQRR 1899

Query: 2032 LVPNEELSMVMSSKKKLTKKTESQSQKRSLHSVSEERTDEMTHKETNEQEERLLATASFT 2091
             V  E L++  S +K    K E + +   + S +E+        E     +R LA A   
Sbjct: 1900 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA-AEEE 1958

Query: 2092 KSSRSSRTRSSKAILLPDLSEPNNEPLFSPASEVPRKAKAKKIEVPAQLKELVSDLSS-Q 2150
            +  R +  R  K++   + +    +     A E   + KA K+E   +L+E     S+ Q
Sbjct: 1959 RRRREAEERVQKSLAAEEEAARQRK----AALEEVERLKA-KVEEARRLRERAEQESARQ 2013

Query: 2151 FVISPPALRSRQKNTSNKN-----KLEDELKDDAQSVETL-----GKPKAKRIRTSKTKQ 2200
              ++  A + R +     +     + E EL+   Q  +++     G+ +A R    + ++
Sbjct: 2014 LQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEE 2073

Query: 2201 ASKNTEKESAWSPPPIE 2217
            A    E+E+A S   +E
Sbjct: 2074 ARVQAEREAAQSRRQVE 2090


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,043,960
Number of Sequences: 37866
Number of extensions: 3977677
Number of successful extensions: 13545
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 578
Number of HSP's that attempted gapping in prelim test: 12082
Number of HSP's gapped (non-prelim): 2028
length of query: 2266
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2148
effective length of database: 13,779,330
effective search space: 29598000840
effective search space used: 29598000840
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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