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Search of human proteins with 66933005
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66933005 calnexin precursor [Homo sapiens]
(592 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66933005 calnexin precursor [Homo sapiens] 1249 0.0
gi|10716563 calnexin precursor [Homo sapiens] 1249 0.0
gi|194578888 calmegin [Homo sapiens] 725 0.0
gi|4758004 calmegin [Homo sapiens] 725 0.0
gi|4757900 calreticulin precursor [Homo sapiens] 275 9e-74
gi|187608348 calreticulin 3 [Homo sapiens] 138 2e-32
gi|17975763 myelin transcription factor 1 [Homo sapiens] 52 1e-06
gi|28274705 family with sequence similarity 9, member A [Homo sa... 51 3e-06
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 50 8e-06
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 49 1e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 49 2e-05
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 49 2e-05
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 48 3e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 48 3e-05
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 48 3e-05
gi|21361639 DIPB protein [Homo sapiens] 47 4e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 47 4e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 47 4e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 47 4e-05
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 47 5e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 6e-05
gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens] 47 6e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 46 8e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 46 8e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 46 8e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 8e-05
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 8e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 8e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 8e-05
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 8e-05
>gi|66933005 calnexin precursor [Homo sapiens]
Length = 592
Score = 1249 bits (3232), Expect = 0.0
Identities = 592/592 (100%), Positives = 592/592 (100%)
Query: 1 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY 60
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
Sbjct: 1 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY 60
Query: 61 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL 120
KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
Sbjct: 61 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL 120
Query: 121 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH 180
VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
Sbjct: 121 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH 180
Query: 181 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL 240
DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
Sbjct: 181 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL 240
Query: 241 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK 300
ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
Sbjct: 241 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK 300
Query: 301 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360
PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
Sbjct: 301 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360
Query: 361 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS 420
ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
Sbjct: 361 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS 420
Query: 421 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER 480
AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
Sbjct: 421 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER 480
Query: 481 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE 540
PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
Sbjct: 481 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE 540
Query: 541 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
Sbjct: 541 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
>gi|10716563 calnexin precursor [Homo sapiens]
Length = 592
Score = 1249 bits (3232), Expect = 0.0
Identities = 592/592 (100%), Positives = 592/592 (100%)
Query: 1 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY 60
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
Sbjct: 1 MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY 60
Query: 61 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL 120
KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
Sbjct: 61 KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL 120
Query: 121 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH 180
VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
Sbjct: 121 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH 180
Query: 181 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL 240
DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
Sbjct: 181 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL 240
Query: 241 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK 300
ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
Sbjct: 241 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK 300
Query: 301 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360
PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
Sbjct: 301 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360
Query: 361 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS 420
ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
Sbjct: 361 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS 420
Query: 421 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER 480
AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
Sbjct: 421 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER 480
Query: 481 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE 540
PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
Sbjct: 481 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE 540
Query: 541 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
Sbjct: 541 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
>gi|194578888 calmegin [Homo sapiens]
Length = 610
Score = 725 bits (1871), Expect = 0.0
Identities = 340/586 (58%), Positives = 434/586 (74%), Gaps = 25/586 (4%)
Query: 11 LVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVY 70
L LG + + DD ++ ED ++ EE++ ++ + S ++ YK P P GEVY
Sbjct: 8 LCLGLLFISINAEFMDDDVETED-FEENSEEIDVNESEL-----SSEIKYKTPQPIGEVY 61
Query: 71 FADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHA 130
FA++FD G L+GW+LSKAKKDD D+EI+ YDG+WE+EE+KE+++PGD+GLVL SRAKHHA
Sbjct: 62 FAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHA 121
Query: 131 ISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFG 190
ISA L KPF+F KPLIVQYEVNFQ+GI+CGGAY+KLL+ T +L L+ F+DKT Y IMFG
Sbjct: 122 ISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMFG 181
Query: 191 PDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEI 250
PDKCGEDYKLHFIFRHK+PKTG++EEKHAK PD DLK +FTD+KTHLYTL++NPD++FE+
Sbjct: 182 PDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEV 241
Query: 251 LVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPA 310
LVDQ+VVN G+LL D+ PP+ P +EIEDP D+KPE+WDER KIPDP AVKP+DWDE PA
Sbjct: 242 LVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPA 301
Query: 311 KIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQ 370
+I D KP GWLDDEP+++PDP+AEKP+DW+ED DGEWEAPQI NP C GCG W+
Sbjct: 302 QIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRI--GCGEWK 359
Query: 371 RPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMT 430
P+IDNP YKG W+PP++DNP+YQGIW PRKIPNPD+FED PF +T FSA+GLELWSMT
Sbjct: 360 PPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMT 419
Query: 431 SDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILT 490
SDI+FDNFIIC+++ + D WA DGW K A +PGV+ Q++ AAE PWLW++Y++T
Sbjct: 420 SDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVT 479
Query: 491 VALPVFLVILFCC--SGKKQTSGMEYKKTDAPQPDVK-----EEEEEK---------EEE 534
+P+ L+ FC KK+ EYKKTD P K EE+EEK EEE
Sbjct: 480 AGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEE 539
Query: 535 KDKGDEEE-EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
K + D E E EE+ E ++KS+ E + +E EDE+
Sbjct: 540 KKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEM 585
>gi|4758004 calmegin [Homo sapiens]
Length = 610
Score = 725 bits (1871), Expect = 0.0
Identities = 340/586 (58%), Positives = 434/586 (74%), Gaps = 25/586 (4%)
Query: 11 LVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVY 70
L LG + + DD ++ ED ++ EE++ ++ + S ++ YK P P GEVY
Sbjct: 8 LCLGLLFISINAEFMDDDVETED-FEENSEEIDVNESEL-----SSEIKYKTPQPIGEVY 61
Query: 71 FADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHA 130
FA++FD G L+GW+LSKAKKDD D+EI+ YDG+WE+EE+KE+++PGD+GLVL SRAKHHA
Sbjct: 62 FAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHA 121
Query: 131 ISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFG 190
ISA L KPF+F KPLIVQYEVNFQ+GI+CGGAY+KLL+ T +L L+ F+DKT Y IMFG
Sbjct: 122 ISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMFG 181
Query: 191 PDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEI 250
PDKCGEDYKLHFIFRHK+PKTG++EEKHAK PD DLK +FTD+KTHLYTL++NPD++FE+
Sbjct: 182 PDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEV 241
Query: 251 LVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPA 310
LVDQ+VVN G+LL D+ PP+ P +EIEDP D+KPE+WDER KIPDP AVKP+DWDE PA
Sbjct: 242 LVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPA 301
Query: 311 KIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQ 370
+I D KP GWLDDEP+++PDP+AEKP+DW+ED DGEWEAPQI NP C GCG W+
Sbjct: 302 QIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRI--GCGEWK 359
Query: 371 RPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMT 430
P+IDNP YKG W+PP++DNP+YQGIW PRKIPNPD+FED PF +T FSA+GLELWSMT
Sbjct: 360 PPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMT 419
Query: 431 SDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILT 490
SDI+FDNFIIC+++ + D WA DGW K A +PGV+ Q++ AAE PWLW++Y++T
Sbjct: 420 SDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVT 479
Query: 491 VALPVFLVILFCC--SGKKQTSGMEYKKTDAPQPDVK-----EEEEEK---------EEE 534
+P+ L+ FC KK+ EYKKTD P K EE+EEK EEE
Sbjct: 480 AGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEE 539
Query: 535 KDKGDEEE-EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
K + D E E EE+ E ++KS+ E + +E EDE+
Sbjct: 540 KKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEM 585
>gi|4757900 calreticulin precursor [Homo sapiens]
Length = 417
Score = 275 bits (703), Expect = 9e-74
Identities = 176/503 (34%), Positives = 246/503 (48%), Gaps = 112/503 (22%)
Query: 69 VYFADSF--DRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRA 126
VYF + F G S WI SK K D + GK+ +E K DKGL A
Sbjct: 21 VYFKEQFLDGDGWTSRWIESKHKSDF--GKFVLSSGKFYGDEEK------DKGLQTSQDA 72
Query: 127 KHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYT 186
+ +A+SA +PF + L+VQ+ V + I+CGG YVKL + L+ H + Y
Sbjct: 73 RFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNS--LDQTDMHGDSEYN 129
Query: 187 IMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPD 245
IMFGPD CG K +H IF +K I ++ K D+ THLYTLI+ PD
Sbjct: 130 IMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCK----------DDEFTHLYTLIVRPD 179
Query: 246 NSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERP--KIPDPEAVKPDD 303
N++E+ +D S V SG+L +DWD P KI DP+A KP+D
Sbjct: 180 NTYEVKIDNSQVESGSL---------------------EDDWDFLPPKKIKDPDASKPED 218
Query: 304 WDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESA 363
WDE A KI D +KPE W D+PE++PDPDA+KPEDWDE+MDGEWE P
Sbjct: 219 WDERA--KIDDPTDSKPEDW--DKPEHIPDPDAKKPEDWDEEMDGEWEPP---------- 264
Query: 364 PGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIG 423
VI NP YKG+WKP IDNP Y+G W +I NP++ D + F +G
Sbjct: 265 ---------VIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLG 315
Query: 424 LELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWL 483
L+LW + S FDNF+I D +++ N+ WG+ KAA+ QM + +E
Sbjct: 316 LDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEK--------QMKDKQDEE--- 364
Query: 484 WVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEE 543
++ + D K +EEE+ E+K+ ++++E
Sbjct: 365 -------------------------------QRLKEEEEDKKRKEEEEAEDKEDDEDKDE 393
Query: 544 GEEKLEEKQKSDAEEDGGTVSQE 566
EE E+K++ + E+ G E
Sbjct: 394 DEEDEEDKEEDEEEDVPGQAKDE 416
Score = 45.1 bits (105), Expect = 2e-04
Identities = 25/68 (36%), Positives = 42/68 (61%), Gaps = 5/68 (7%)
Query: 517 TDAPQPDVKEEEEE----KEEEKDKG-DEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
T A + +K++++E KEEE+DK EEEE E+K +++ K + EED ++EE+
Sbjct: 350 TKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDV 409
Query: 572 PKAEEDEI 579
P +DE+
Sbjct: 410 PGQAKDEL 417
Score = 32.7 bits (73), Expect = 0.96
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 5/47 (10%)
Query: 536 DKGDEEEEGEE-----KLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
D+ EE G E K EKQ D +++ + +EEED+K K EE+
Sbjct: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEE 381
>gi|187608348 calreticulin 3 [Homo sapiens]
Length = 384
Score = 138 bits (347), Expect = 2e-32
Identities = 101/354 (28%), Positives = 150/354 (42%), Gaps = 84/354 (23%)
Query: 117 DKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNL 176
DKGL + +AISA+ KPF K L++QY V + ++CGG Y+K+ +++
Sbjct: 63 DKGLQTTQNGRFYAISARF-KPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPA--DIDQ 119
Query: 177 DQFHDKTPYTIMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKT 235
+ K+ Y IMFGPD CG D K +H I KN +E K R D T
Sbjct: 120 KNLNGKSQYYIMFGPDICGFDIKKVHVILHFKNK---YHENKKLIRCKVD-------GFT 169
Query: 236 HLYTLILNPDNSFEILVDQSVVNSGNL-----LNDMTPPVNP--SREIEDPEDRKPEDWD 288
HLYTLIL PD S+++ +D + SG++ L + +P S++ E +D K +DW+
Sbjct: 170 HLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWE 229
Query: 289 ERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDG 348
+ D K DW+ D +DG
Sbjct: 230 KH--FLDASTSKQSDWNGD--------------------------------------LDG 249
Query: 349 EWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFF 408
+W A P++ P Y+ KP I ++ +W RK+ N D+
Sbjct: 250 DWPA-------------------PMLQKPPYQDGLKPEGI----HKDVWLHRKMKNTDYL 286
Query: 409 EDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAAD 462
+ AIGLELW + S FDNF+I D D++ WG K +
Sbjct: 287 TQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYADNFGKATWGETKGPE 340
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 52.4 bits (124), Expect = 1e-06
Identities = 46/130 (35%), Positives = 68/130 (52%), Gaps = 22/130 (16%)
Query: 457 LKKAADGAA-EPGVVGQMI--EAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSGME 513
L++AA+GAA E G G I E AEE VV + T C + + E
Sbjct: 198 LQEAAEGAASEEGEKGLFIQPEDAEE-----VVEVTTERSQDL-----CPQSLEDAASEE 247
Query: 514 YKKTDA----PQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEED 569
K + D +EEEEE+EEE+D+ +EEEE EE+ EE+++ + EE+ +EEE+
Sbjct: 248 SSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE-----EEEEE 302
Query: 570 RKPKAEEDEI 579
+ +A D I
Sbjct: 303 EEEEAAPDVI 312
Score = 34.7 bits (78), Expect = 0.25
Identities = 18/68 (26%), Positives = 35/68 (51%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
E ++ + + + +EEEEE+EEE+++ +EEE + + ++ S + E P
Sbjct: 277 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSP 336
Query: 573 KAEEDEIL 580
K E I+
Sbjct: 337 KPEYSVIV 344
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 51.2 bits (121), Expect = 3e-06
Identities = 26/56 (46%), Positives = 39/56 (69%), Gaps = 2/56 (3%)
Query: 526 EEEEEKEEEKDKGDEEEEGEEK--LEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
EEEEEKEEE++K +EEEEGEE+ EE ++ +G +EEE+ + + EE++I
Sbjct: 222 EEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQI 277
Score = 44.3 bits (103), Expect = 3e-04
Identities = 21/51 (41%), Positives = 35/51 (68%)
Query: 528 EEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
E+E+EEEK++ +E+EE EE+ EE+ + E+GG + EE + + EE+E
Sbjct: 220 EDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEE 270
Score = 43.1 bits (100), Expect = 7e-04
Identities = 21/52 (40%), Positives = 34/52 (65%)
Query: 527 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
E+EE+EE++++ ++EEE EE EE + EE GG EE + + + EE+E
Sbjct: 220 EDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEE 271
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEE------EGEEKLEEKQKSDAEEDGGTVSQEEE 568
++ + + + KEEEEE+ EE+ G+E E EGEE EE+++ + EE+ + +E
Sbjct: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
Query: 569 DRKPKAEEDEILNRSPRNRKPRRE 592
+K + + + R KP E
Sbjct: 283 KQKRWQQPTGVRSWRLREMKPLLE 306
Score = 32.0 bits (71), Expect = 1.6
Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
G+++ G E ++ + EEEE+EEE+ +EEEE + +EKQK ++ G S
Sbjct: 240 GEEEGGGEEGEEGGGGGEGEETEEEEEEEEE---EEEEEQIKAFQEKQKR-WQQPTGVRS 295
Query: 565 QEEEDRKPKAEE 576
+ KP E+
Sbjct: 296 WRLREMKPLLEQ 307
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 49.7 bits (117), Expect = 8e-06
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 3/73 (4%)
Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEE---EGEEKLEEKQKSDAEEDGGTV 563
K+ E KK + + ++EEEE+EE K K +EEE + EE+ E K + D +EDGG
Sbjct: 374 KEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQK 433
Query: 564 SQEEEDRKPKAEE 576
+ E + P EE
Sbjct: 434 PEGEPQQDPGTEE 446
Score = 46.6 bits (109), Expect = 6e-05
Identities = 30/66 (45%), Positives = 43/66 (65%), Gaps = 5/66 (7%)
Query: 515 KKTDAPQPDVKEEEEE--KEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
K+ A Q ++KE+EEE K+EE+ K EE+E EE+ E KQK + EE ++ EE+ +
Sbjct: 364 KRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEE---IRNKNEEEGES 420
Query: 573 KAEEDE 578
K EEDE
Sbjct: 421 KDEEDE 426
Score = 45.1 bits (105), Expect = 2e-04
Identities = 23/78 (29%), Positives = 50/78 (64%), Gaps = 5/78 (6%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQ-KSDAEEDGGTVS 564
+K+ + + + + ++K+EEE K++E+ + +EEEE ++K EE++ ++ EE+G +
Sbjct: 363 RKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKD 422
Query: 565 QEEED----RKPKAEEDE 578
+E+ED +KP+ E +
Sbjct: 423 EEDEDEDGGQKPEGEPQQ 440
Score = 44.3 bits (103), Expect = 3e-04
Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD--AEEDGGTV 563
+K+ E K + +++ + EE+ E KD+ DE+E+G +K E + + D EE G V
Sbjct: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
Query: 564 SQEEEDRKPKAEEDEILNRSP 584
+E D + DE++ P
Sbjct: 452 EEEPLDEAQDDDLDELMEMEP 472
Score = 40.0 bits (92), Expect = 0.006
Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 5/65 (7%)
Query: 525 KEEEEEKEEEKDKGDE-----EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
++E +EKEEE+ K +E EE+ EE+ EE ++ + EE+ ++EE + K + +EDE
Sbjct: 370 QQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDED 429
Query: 580 LNRSP 584
+ P
Sbjct: 430 GGQKP 434
Score = 38.9 bits (89), Expect = 0.013
Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAE--EDGGTV 563
++++ EY D Q + K++ K ++E +EK EE+ K + E +
Sbjct: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
+EEE+ K K EE+EI N++ + + E
Sbjct: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDE 423
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 49.3 bits (116), Expect = 1e-05
Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 13/99 (13%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEE-----------KDKGDEEEEGEEKLEEKQK 553
GK++ E +K + KE E+ KE+E K K +EE E EE+ EE++K
Sbjct: 27 GKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEK 86
Query: 554 SDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
+ E++ G ++++ R+ K EE+E + R RK +++
Sbjct: 87 EEEEKEEGRRRKKKKKRRRKEEEEE--KKKKRRRKTKKK 123
Score = 47.0 bits (110), Expect = 5e-05
Identities = 25/87 (28%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
+++ G +K + + +++++ KE EK K EEEE + K + K+K + EE+ +
Sbjct: 22 EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE-EEEREEEEE 80
Query: 566 EEEDRKPKAEEDEILNRSPRNRKPRRE 592
EEE+ K + E++E R + ++ R+E
Sbjct: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKE 107
Score = 44.3 bits (103), Expect = 3e-04
Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%)
Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD-AEEDGGTVSQEEEDRKPKAEEDEILNRS 583
K++E E+ EE ++ +EEEE E K +EK+K E++ ++E E RK K EE++ R
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65
Query: 584 PRNRKPRRE 592
+ +K E
Sbjct: 66 RKKKKEEEE 74
Score = 41.2 bits (95), Expect = 0.003
Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 5/69 (7%)
Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEED----- 569
KK + + + EE EE+EE++ K E+ + + K +EK+K E + +EEE
Sbjct: 6 KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65
Query: 570 RKPKAEEDE 578
RK K EE+E
Sbjct: 66 RKKKKEEEE 74
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 48.5 bits (114), Expect = 2e-05
Identities = 24/69 (34%), Positives = 44/69 (63%), Gaps = 6/69 (8%)
Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDA------EEDGGTVSQEEE 568
++ + + + +EEEEE+EEE+D +EEE+ EE EE+++ + EE+ G + +EEE
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 569 DRKPKAEED 577
+ + EE+
Sbjct: 948 EEDEEEEEE 956
Score = 47.0 bits (110), Expect = 5e-05
Identities = 25/53 (47%), Positives = 38/53 (71%), Gaps = 1/53 (1%)
Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
EEEEE+EEE+++ +EEEE EE EE+++ D EE +EEE+ + + EE+E
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEE-DEEEYFEEEEEEEEEFEEEFEEEE 939
Score = 43.9 bits (102), Expect = 4e-04
Identities = 21/58 (36%), Positives = 39/58 (67%)
Query: 521 QPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
+ + +EEEEE+EEE+++ +E+ E EE+ EE+ + EE+ +E E+ + + EE+E
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Score = 43.9 bits (102), Expect = 4e-04
Identities = 23/66 (34%), Positives = 42/66 (63%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
E ++ + + + +EEE+ +EEE+D+ + EE EE+ EE ++ EE+G +EEE+ +
Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEE 952
Query: 573 KAEEDE 578
+ EE E
Sbjct: 953 EEEELE 958
Score = 42.4 bits (98), Expect = 0.001
Identities = 22/67 (32%), Positives = 43/67 (64%), Gaps = 5/67 (7%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
E ++ + + D +EEEE++EE ++ +EEEE E+ E+++ + EE+ +EEED +
Sbjct: 899 EEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE-----EEEEDEEE 953
Query: 573 KAEEDEI 579
+ E +E+
Sbjct: 954 EEELEEV 960
Score = 35.8 bits (81), Expect = 0.11
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 528 EEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
EE+ +EEE EE+ EE+++ + EE+ +EEED + EE+E
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE 925
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/59 (35%), Positives = 39/59 (66%), Gaps = 3/59 (5%)
Query: 513 EYKKTDAPQPDVKEEE--EEKEEEKDKGDEE-EEGEEKLEEKQKSDAEEDGGTVSQEEE 568
E ++ D + + EEE EE+EEE+++ +EE EE E +LEE+++ + EE+ + + E+
Sbjct: 904 EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/60 (35%), Positives = 34/60 (56%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
EY + + + + EEE E+EE + + +EEEE EE+ EE ++ + E G + EE P
Sbjct: 919 EYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPP 978
Score = 30.0 bits (66), Expect = 6.2
Identities = 17/78 (21%), Positives = 43/78 (55%), Gaps = 2/78 (2%)
Query: 270 VNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPE 329
+N S E E+ E+ + E+ +E + + E + ++ DE+ + +EE + E ++E
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEE--EEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG 940
Query: 330 YVPDPDAEKPEDWDEDMD 347
+ + + E+ E+ +E+++
Sbjct: 941 ELEEEEEEEDEEEEEELE 958
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/78 (34%), Positives = 47/78 (60%), Gaps = 5/78 (6%)
Query: 503 CSGKKQTSGMEYKKTDAPQPDVKEEEE--EKEEEKDKGDEEEEGEEKLEEKQKSDAEEDG 560
C T M+ K+ D + ++ +E +++EE ++GD EEE E++EE+ + D +EDG
Sbjct: 90 CDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEE--EEIEEEDEDD-DEDG 146
Query: 561 GTVSQEEEDRKPKAEEDE 578
V EEE+ + + EE+E
Sbjct: 147 EDVEDEEEEEEEEEEEEE 164
Score = 33.1 bits (74), Expect = 0.74
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Query: 502 CCSGKKQTSGMEYKKTDAPQ--PDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED 559
C KK+ + + + AP+ P + + +E D D E+ +EK E++ + +E++
Sbjct: 55 CPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDN 114
Query: 560 GGTVSQEEEDRKPKAEEDE 578
++EED + EE+E
Sbjct: 115 DEPGDEDEEDEEGDREEEE 133
Score = 32.0 bits (71), Expect = 1.6
Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 4/65 (6%)
Query: 516 KTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQK--SDAEEDGGTVSQEEEDRKPK 573
K D+ D ++ + E+ +K EE+EGEE E+ + + EED +EEE+ + +
Sbjct: 81 KADSSSVDECDDSDGTEDMDEK--EEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE 138
Query: 574 AEEDE 578
E+D+
Sbjct: 139 DEDDD 143
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 47.8 bits (112), Expect = 3e-05
Identities = 23/59 (38%), Positives = 39/59 (66%)
Query: 521 QPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
Q + EEEE EEE+++ +EEE+ EEK E++++ + EE+ +EEE K EE+++
Sbjct: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171
Score = 47.4 bits (111), Expect = 4e-05
Identities = 30/95 (31%), Positives = 54/95 (56%), Gaps = 9/95 (9%)
Query: 489 LTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKL 548
L+VA LV C + + G+ ++ + + + + EEEEKEEEK++ +EEEE EE+
Sbjct: 97 LSVARTAALVAEECSAQQ----GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEK 152
Query: 549 EEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRS 583
EE ++ + +E ++ E+ K + E D + R+
Sbjct: 153 EEDEEEEEKE-----GKKMEEEKVEEEIDTEIQRT 182
Score = 35.8 bits (81), Expect = 0.11
Identities = 19/69 (27%), Positives = 37/69 (53%)
Query: 524 VKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRS 583
V EE ++ + +E EE EE++EE++K + +E+ ++EE+++ EE+E +
Sbjct: 106 VAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKK 165
Query: 584 PRNRKPRRE 592
K E
Sbjct: 166 MEEEKVEEE 174
Score = 35.4 bits (80), Expect = 0.15
Identities = 16/56 (28%), Positives = 36/56 (64%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEE 568
E + + + + +E+EEE+E+E++K ++EEE E++ ++ ++ EE+ T Q +
Sbjct: 128 EEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 47.8 bits (112), Expect = 3e-05
Identities = 24/61 (39%), Positives = 41/61 (67%), Gaps = 5/61 (8%)
Query: 520 PQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
PQ + KEEEEE+EE++++ +E+EE EE+ EE+++ + EE+ +EEE+ E+
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEE-----EEEEEAAAAVALGEV 781
Query: 580 L 580
L
Sbjct: 782 L 782
Score = 45.4 bits (106), Expect = 1e-04
Identities = 22/54 (40%), Positives = 37/54 (68%), Gaps = 5/54 (9%)
Query: 521 QPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKA 574
QP +EEE+EEE+D+ +EEE+ EE+ EE+++ + EE+ +EEE+ + A
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEE-----EEEEEEEAAA 774
Score = 43.9 bits (102), Expect = 4e-04
Identities = 18/44 (40%), Positives = 34/44 (77%)
Query: 516 KTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED 559
+ + + + +EEE+E+EEE+D+ +EEEE EE+ EE+++ + EE+
Sbjct: 728 QANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 41.2 bits (95), Expect = 0.003
Identities = 20/49 (40%), Positives = 37/49 (75%), Gaps = 2/49 (4%)
Query: 508 QTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDA 556
Q +G E ++ + + D +EEEE++EEE+++ +EEEE EE+ EE++++ A
Sbjct: 728 QANGKEEEEEE--EEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAA 774
Score = 39.7 bits (91), Expect = 0.008
Identities = 19/55 (34%), Positives = 33/55 (60%)
Query: 520 PQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKA 574
P V+ + KEEE+++ ++EEE EE EE+++ + EE+ +EEE+ A
Sbjct: 721 PLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAA 775
Score = 36.6 bits (83), Expect = 0.067
Identities = 17/40 (42%), Positives = 27/40 (67%)
Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEE 546
K+ E + + + D +EEEEE+EEE+++ +EEEE EE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 36.2 bits (82), Expect = 0.087
Identities = 16/42 (38%), Positives = 29/42 (69%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGE 545
+GK++ E + + + + +EEEEE+EEE+++ +EEEE E
Sbjct: 730 NGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 32.3 bits (72), Expect = 1.3
Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 27/103 (26%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEE------------------EEGEEKLEEKQK- 553
E ++ D + + +EEEEE+EEE+++ +EE EG E+ ++ +
Sbjct: 743 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQE 802
Query: 554 --------SDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
D +E G S + D +P+ ++ SP + K
Sbjct: 803 GAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMK 845
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 47.8 bits (112), Expect = 3e-05
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
S K S +Y + +P E + E K+ +EEEE E++ EE+++ + EED
Sbjct: 1035 SPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEED---- 1090
Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
+EEE+ + + EE+ I + PR KP+
Sbjct: 1091 EEEEEEEEEEEEEENIQSSPPRLTKPQ 1117
Score = 46.2 bits (108), Expect = 8e-05
Identities = 29/77 (37%), Positives = 45/77 (58%), Gaps = 5/77 (6%)
Query: 502 CCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGG 561
C TS E + D +P+ +EEEEE+EEE+ +EEEEGEE EE + ++ G
Sbjct: 1330 CAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEE---EEEEEGEE--EEGGGNVEKDPDG 1384
Query: 562 TVSQEEEDRKPKAEEDE 578
SQE+E+ + E+++
Sbjct: 1385 AKSQEKEEPEISTEKED 1401
Score = 44.3 bits (103), Expect = 3e-04
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 10/73 (13%)
Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSP 584
+EEEEE EEE+++ +EEEE EE+ EE+++ + EE+ Q R K + I + P
Sbjct: 1071 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN----IQSSPPRLTKPQSVAIKRKRP 1126
Query: 585 ------RNRKPRR 591
R RK RR
Sbjct: 1127 FVLKKKRGRKRRR 1139
Score = 38.5 bits (88), Expect = 0.018
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 8/73 (10%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGE----EKLEEKQKSDAEEDGGTV----S 564
E ++ + + + +EEEEE EEE+ G+ E++ + ++ EE + S +ED +
Sbjct: 1351 EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEE 1410
Query: 565 QEEEDRKPKAEED 577
+EEED +P ED
Sbjct: 1411 EEEEDEEPSHNED 1423
Score = 34.7 bits (78), Expect = 0.25
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 2/68 (2%)
Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEE-KLEEKQKSDAEEDGGTVSQE-EEDRKP 572
K + +P++ E+E+ D +EEEE EE E +D E+D S E E++ P
Sbjct: 1386 KSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELP 1445
Query: 573 KAEEDEIL 580
+ E+L
Sbjct: 1446 RESFKEVL 1453
Score = 31.6 bits (70), Expect = 2.1
Identities = 14/56 (25%), Positives = 31/56 (55%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED 559
S +K+ + +K D+ + D EEEEE++EE ++ + +E + ++ E++
Sbjct: 1387 SQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKE 1442
Score = 30.4 bits (67), Expect = 4.8
Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 32/137 (23%)
Query: 259 SGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDP-----------EAVKPDDWDE- 306
+G LN TPP P E + ++ E P P EA+ P + +
Sbjct: 1267 TGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRR 1326
Query: 307 ----------DAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPED------WDEDMDG-- 348
+P + P+++ KPE ++E E + + E+ E+ ++D DG
Sbjct: 1327 EETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAK 1386
Query: 349 --EWEAPQIANPRCESA 363
E E P+I+ + +SA
Sbjct: 1387 SQEKEEPEISTEKEDSA 1403
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 47.4 bits (111), Expect = 4e-05
Identities = 22/59 (37%), Positives = 40/59 (67%), Gaps = 2/59 (3%)
Query: 521 QPDVKEEEEEKEEEKDKGDEE--EEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
+ + +EE E +EE +D+ DEE E+ EE++E++Q+S+AEED + E + + +AE +
Sbjct: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESE 162
Score = 40.0 bits (92), Expect = 0.006
Identities = 16/55 (29%), Positives = 35/55 (63%)
Query: 523 DVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
+++ E E+ E +++ + EEE E + E + +SD E + + + E++++ +AEED
Sbjct: 90 EIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEED 144
Score = 38.5 bits (88), Expect = 0.018
Identities = 23/78 (29%), Positives = 44/78 (56%), Gaps = 3/78 (3%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEE-EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
++++ E +T+ D +EE EE EE+ + ++E E EE +E+ +S+AE G T +
Sbjct: 102 EEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAE--GETEA 159
Query: 565 QEEEDRKPKAEEDEILNR 582
+ E D + + E + + R
Sbjct: 160 ESEFDPEIEMEAERVAKR 177
Score = 37.4 bits (85), Expect = 0.039
Identities = 18/52 (34%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
+EE E + E+++ E E GEE E +++S++EE+ T + E++ ++EED
Sbjct: 78 KEEAEVKVEQEREIESEAGEES-ESEEESESEEESETEEESEDESDEESEED 128
Score = 37.4 bits (85), Expect = 0.039
Identities = 21/52 (40%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
Query: 528 EEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAE-EDE 578
E+E+E E + G EE E EE+ E +++S+ EE+ S EE + + E EDE
Sbjct: 86 EQEREIESEAG-EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136
Score = 34.3 bits (77), Expect = 0.33
Identities = 17/64 (26%), Positives = 35/64 (54%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
E + + + D +EE E+++E + + D +EEGE + E + ++++E D + E K
Sbjct: 118 EDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKR 177
Query: 573 KAEE 576
K +
Sbjct: 178 KCPD 181
Score = 33.9 bits (76), Expect = 0.43
Identities = 17/53 (32%), Positives = 24/53 (45%)
Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
E+E E E E + E EE E EE + + ED EE+ + +E E
Sbjct: 86 EQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQE 138
Score = 32.7 bits (73), Expect = 0.96
Identities = 25/97 (25%), Positives = 47/97 (48%), Gaps = 8/97 (8%)
Query: 270 VNPSREIEDP--EDRKPEDWDERPKIPDPEAVKPDDWDE----DAPAKIPDEEATKPEGW 323
V REIE E+ + E+ E + + E D+ DE D+ ++ DE+ ++ E
Sbjct: 85 VEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEED 144
Query: 324 LDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360
+E E + + E ++D ++ E EA ++A +C
Sbjct: 145 NQEEGESEAEGETEAESEFDPEI--EMEAERVAKRKC 179
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 47.4 bits (111), Expect = 4e-05
Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 6/60 (10%)
Query: 519 APQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
A P+VKEEE EKEEE+ + +EEEE +E KSD E+GG+ +E K + E++E
Sbjct: 515 ATAPEVKEEEGEKEEEEGQEEEEEE-----DEGAKSDQAEEGGS-EKEGSSEKEEGEQEE 568
Score = 39.3 bits (90), Expect = 0.010
Identities = 21/68 (30%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKD-KGDEEEE-GEEKLEEKQKSDAEEDGGTVSQEEEDR 570
E K+ + + + + +EEE+EE++ K D+ EE G EK +K + E++ G E E
Sbjct: 519 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE 578
Query: 571 KPKAEEDE 578
+ +A+E++
Sbjct: 579 EAEAKEEK 586
Score = 35.4 bits (80), Expect = 0.15
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 10/77 (12%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGD---------EEEEGEEKLEEKQKSDAEED-GG 561
M+ +K +A + +E E E+EE K +EEEGE++ EE Q+ + EED G
Sbjct: 484 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 543
Query: 562 TVSQEEEDRKPKAEEDE 578
Q EE K E
Sbjct: 544 KSDQAEEGGSEKEGSSE 560
Score = 33.5 bits (75), Expect = 0.56
Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD----AEEDGGTVSQEEEDR 570
+K +P P EE + + E KG+++EE E++++E K + EE V ++++
Sbjct: 676 EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAE 735
Query: 571 KPKAEE 576
P EE
Sbjct: 736 SPVKEE 741
Score = 33.1 bits (74), Expect = 0.74
Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 8/82 (9%)
Query: 509 TSGMEYKKTDAPQPDVKEE-EEEKEEEKDKGDEEEEGEEKL----EEKQKSDAEEDGGTV 563
+S ++ K +AP+ V+ + EE EE DE+ E EE L EE S EE
Sbjct: 433 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 492
Query: 564 SQEEEDRKPKAEEDEI-LNRSP 584
++EE+ P+AEE+E+ +SP
Sbjct: 493 EEKEEE--PEAEEEEVAAKKSP 512
Score = 33.1 bits (74), Expect = 0.74
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 527 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRN 586
E+EE E+E+ + + E EGEE +++K E+ ++EE K E+ E +SP
Sbjct: 560 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE-KAKSPVP 618
Query: 587 RKPRRE 592
+ P E
Sbjct: 619 KSPVEE 624
Score = 31.6 bits (70), Expect = 2.1
Identities = 16/49 (32%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 526 EEEEEKEEEKDKGDEEEEGEEK-LEEKQKSDAEEDGGTVSQEEEDRKPK 573
++E+EKE+ +G EEEG +K + +K D +G +EE +++ K
Sbjct: 769 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 817
Score = 29.6 bits (65), Expect = 8.2
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED---- 559
S + + G E K+ + + + ++EE E E E + + E + E+K+EEK + A ++
Sbjct: 545 SDQAEEGGSE-KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 603
Query: 560 GGTVSQEEEDRKPKAEED-EILNRSPRNRKPRRE 592
V + E+ + P + E +SP + P E
Sbjct: 604 DAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEE 637
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 47.4 bits (111), Expect = 4e-05
Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 6/60 (10%)
Query: 519 APQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
A P+VKEEE EKEEE+ + +EEEE +E KSD E+GG+ +E K + E++E
Sbjct: 139 ATAPEVKEEEGEKEEEEGQEEEEEE-----DEGAKSDQAEEGGS-EKEGSSEKEEGEQEE 192
Score = 39.3 bits (90), Expect = 0.010
Identities = 21/68 (30%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKD-KGDEEEE-GEEKLEEKQKSDAEEDGGTVSQEEEDR 570
E K+ + + + + +EEE+EE++ K D+ EE G EK +K + E++ G E E
Sbjct: 143 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE 202
Query: 571 KPKAEEDE 578
+ +A+E++
Sbjct: 203 EAEAKEEK 210
Score = 35.4 bits (80), Expect = 0.15
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 10/77 (12%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGD---------EEEEGEEKLEEKQKSDAEED-GG 561
M+ +K +A + +E E E+EE K +EEEGE++ EE Q+ + EED G
Sbjct: 108 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 167
Query: 562 TVSQEEEDRKPKAEEDE 578
Q EE K E
Sbjct: 168 KSDQAEEGGSEKEGSSE 184
Score = 33.5 bits (75), Expect = 0.56
Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD----AEEDGGTVSQEEEDR 570
+K +P P EE + + E KG+++EE E++++E K + EE V ++++
Sbjct: 300 EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAE 359
Query: 571 KPKAEE 576
P EE
Sbjct: 360 SPVKEE 365
Score = 33.1 bits (74), Expect = 0.74
Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 8/82 (9%)
Query: 509 TSGMEYKKTDAPQPDVKEE-EEEKEEEKDKGDEEEEGEEKL----EEKQKSDAEEDGGTV 563
+S ++ K +AP+ V+ + EE EE DE+ E EE L EE S EE
Sbjct: 57 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 116
Query: 564 SQEEEDRKPKAEEDEI-LNRSP 584
++EE+ P+AEE+E+ +SP
Sbjct: 117 EEKEEE--PEAEEEEVAAKKSP 136
Score = 33.1 bits (74), Expect = 0.74
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 527 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRN 586
E+EE E+E+ + + E EGEE +++K E+ ++EE K E+ E +SP
Sbjct: 184 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE-KAKSPVP 242
Query: 587 RKPRRE 592
+ P E
Sbjct: 243 KSPVEE 248
Score = 31.6 bits (70), Expect = 2.1
Identities = 16/49 (32%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 526 EEEEEKEEEKDKGDEEEEGEEK-LEEKQKSDAEEDGGTVSQEEEDRKPK 573
++E+EKE+ +G EEEG +K + +K D +G +EE +++ K
Sbjct: 393 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 441
Score = 29.6 bits (65), Expect = 8.2
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED---- 559
S + + G E K+ + + + ++EE E E E + + E + E+K+EEK + A ++
Sbjct: 169 SDQAEEGGSE-KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227
Query: 560 GGTVSQEEEDRKPKAEED-EILNRSPRNRKPRRE 592
V + E+ + P + E +SP + P E
Sbjct: 228 DAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEE 261
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 47.4 bits (111), Expect = 4e-05
Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 5/74 (6%)
Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
++T +E K + EEEEE+EEE+++ +E EE EE+ E + S+ +E+ VS E
Sbjct: 513 EETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDE 572
Query: 567 EE-----DRKPKAE 575
++ D+KP E
Sbjct: 573 KDSGKTLDKKPSKE 586
Score = 43.5 bits (101), Expect = 5e-04
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 4/62 (6%)
Query: 523 DVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNR 582
+VKE EE+EEE +EEEE +E+ EE+++ + E +G +E+E + + + L++
Sbjct: 526 EVKENPEEEEEE----EEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDK 581
Query: 583 SP 584
P
Sbjct: 582 KP 583
Score = 41.6 bits (96), Expect = 0.002
Identities = 24/83 (28%), Positives = 48/83 (57%), Gaps = 7/83 (8%)
Query: 510 SGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEED 569
S E +K + + ++ +E +EEE+++ +EEE+ E + EE+++ ++E G +EED
Sbjct: 511 SDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEG----DEED 566
Query: 570 RKPKAEEDEILNRSPRNRKPRRE 592
K E+D + ++KP +E
Sbjct: 567 EKVSDEKD---SGKTLDKKPSKE 586
Score = 39.3 bits (90), Expect = 0.010
Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEE-EKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
KK S K +KEEEE +K EE+++ EE E K +E+++ + E+
Sbjct: 333 KKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQ 392
Query: 565 QEEEDRKPKAEEDEILNRSPRNRKPRRE 592
+E+E ++ +E ++L +S R + R E
Sbjct: 393 KEKERKERLKKEGKLLTKSQREARARAE 420
Score = 38.1 bits (87), Expect = 0.023
Identities = 20/85 (23%), Positives = 42/85 (49%)
Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
K+ E ++ + + D + EEEE+EE + +G E +E +EK+ +++ S D +
Sbjct: 528 KENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEM 587
Query: 567 EEDRKPKAEEDEILNRSPRNRKPRR 591
D + +++D ++ RR
Sbjct: 588 SSDSEYDSDDDRTKEERAYDKAKRR 612
Score = 37.7 bits (86), Expect = 0.030
Identities = 21/76 (27%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 519 APQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD--AEEDGGTVSQEEEDRKPKAEE 576
A + D + ++++K+++K KG++EE+ +EK + K+ A ++ +EEE+R+ + EE
Sbjct: 304 AAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE 363
Query: 577 DEILNRSPRNRKPRRE 592
+ I K + E
Sbjct: 364 ERIKRLEELEAKRKEE 379
Score = 37.7 bits (86), Expect = 0.030
Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 9/75 (12%)
Query: 525 KEEEEEKEEEKDKGDEE------EEGEEKL-EEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
K E+EEKE+EK KG + +E KL EE+++ EE+ EE + K K E+
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRK--EE 379
Query: 578 EILNRSPRNRKPRRE 592
E L + R RK ++E
Sbjct: 380 ERLEQEKRERKKQKE 394
Score = 37.7 bits (86), Expect = 0.030
Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 21/139 (15%)
Query: 210 KTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPP 269
K IYE+K K+ L++ + S E+ V+ G + TPP
Sbjct: 442 KRPIYEDKKRKKIPQQLESKEVSE-------------SMELCAAVEVMEQGVPEKEETPP 488
Query: 270 VNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPE 329
E ED ED +DW+ + E V+ + K+ E PE ++E E
Sbjct: 489 PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGN--------KVHIEVKENPEEEEEEEEE 540
Query: 330 YVPDPDAEKPEDWDEDMDG 348
D ++E+ E+ + + +G
Sbjct: 541 EEEDEESEEEEEEEGESEG 559
Score = 36.6 bits (83), Expect = 0.067
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 506 KKQTSGMEYKKTD---APQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGT 562
K + E KK D A +KE+EE + +KD+ ++E + EE KS D G
Sbjct: 232 KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGV 291
Query: 563 V-SQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
+ + EE+ P A ED+ N + +K +++
Sbjct: 292 IPASEEKAETPTAAEDD--NEGDKKKKDKKK 320
Score = 32.0 bits (71), Expect = 1.6
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNR 582
+++ E+KE E+ K DEE+ KL+EK++ E G ++++ + K EE+ + ++
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEEL---ETGKKDQSKQKESQRKFEEETVKSK 284
Score = 31.6 bits (70), Expect = 2.1
Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 17/94 (18%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKD---------KGDEEEEGEEKLEEK--- 551
S K+ G + KK D +E E++ + K G ++++ KL +K
Sbjct: 93 SKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKG 152
Query: 552 --QKSDAEEDGGTVSQEEEDRKPKAEEDEILNRS 583
QKS+ + DG S+E+ED K +E +N S
Sbjct: 153 KAQKSNKKWDG---SEEDEDNSKKIKERSRINSS 183
Score = 31.2 bits (69), Expect = 2.8
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 6/83 (7%)
Query: 516 KTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAE 575
K D VK E +EE K +++ + K + +D+EE S+ ++ KPK E
Sbjct: 73 KADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVE 132
Query: 576 ------EDEILNRSPRNRKPRRE 592
+D+ N+ P+ K + +
Sbjct: 133 MYSGSDDDDDFNKLPKKAKGKAQ 155
Score = 31.2 bits (69), Expect = 2.8
Identities = 25/118 (21%), Positives = 46/118 (38%), Gaps = 29/118 (24%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEE----------EEEKEEEKDKGDEEEEGEEKLEEKQK 553
+GKK S + + + VK + EEK E +++ EG++K ++K+K
Sbjct: 261 TGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKK 320
Query: 554 SDAEED-------------------GGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
E++ +EE+ + K EE+E + R R+E
Sbjct: 321 KKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKE 378
Score = 29.6 bits (65), Expect = 8.2
Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 12/97 (12%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEK-----DKGDEEEEGEEKLEEKQKSDAEED 559
GK Q S KK D + D ++ KE + + GDE +E + + ++K+ +
Sbjct: 152 GKAQKSN---KKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKP 208
Query: 560 GGTVSQEEEDR----KPKAEEDEILNRSPRNRKPRRE 592
G + ED K K + + R RK R E
Sbjct: 209 GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDE 245
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 47.0 bits (110), Expect = 5e-05
Identities = 21/67 (31%), Positives = 45/67 (67%), Gaps = 4/67 (5%)
Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPR 585
EEEEE+EEE+++ DEEEEG+++ ++ +++ ++ +EE + P+ + +E+++ P+
Sbjct: 270 EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKE----FKEEGEEIPRVKPEEMMDERPK 325
Query: 586 NRKPRRE 592
R +E
Sbjct: 326 TRSQEQE 332
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 516 KTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPK-- 573
KT+ + + +EEEE+ EEE+ + ++ E + ++ K + EE +E D +PK
Sbjct: 268 KTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTR 327
Query: 574 AEEDEILNRSPRNRKPRRE 592
++E E+L R R + + E
Sbjct: 328 SQEQEVLERGGRFTRSQEE 346
Score = 35.4 bits (80), Expect = 0.15
Identities = 18/68 (26%), Positives = 34/68 (50%)
Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSP 584
KE+EEE+++E++K E E + EK++ + E +E E + + D +R
Sbjct: 1253 KEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRER 1312
Query: 585 RNRKPRRE 592
+ RR+
Sbjct: 1313 GRERDRRD 1320
Score = 32.3 bits (72), Expect = 1.3
Identities = 16/68 (23%), Positives = 34/68 (50%)
Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSP 584
+ +E EK ++ + +E++E E++ E ++ E + E DR+ + E +
Sbjct: 1244 RAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRD 1303
Query: 585 RNRKPRRE 592
R+R+ RE
Sbjct: 1304 RDRERDRE 1311
Score = 31.2 bits (69), Expect = 2.8
Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 7/69 (10%)
Query: 524 VKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRS 583
V++E E E K++ +E EE+ +++++ +AE + + E+ R+ E D
Sbjct: 1235 VQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERD------ 1288
Query: 584 PRNRKPRRE 592
R R+ RE
Sbjct: 1289 -RERERERE 1296
Score = 29.6 bits (65), Expect = 8.2
Identities = 14/67 (20%), Positives = 35/67 (52%)
Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPR 585
E +E+E+ + + +EEE+ E + E +++ + + + + +R + E + +R R
Sbjct: 1243 ERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDR 1302
Query: 586 NRKPRRE 592
+R R+
Sbjct: 1303 DRDRERD 1309
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 46.6 bits (109), Expect = 6e-05
Identities = 24/56 (42%), Positives = 41/56 (73%), Gaps = 1/56 (1%)
Query: 525 KEEEEEKEEEKDKGDEE-EEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
KEEEE+K+++K+K EE +E EE EEK++ +EE+ ++S EEE+ + + E+E+
Sbjct: 2282 KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV 2337
Score = 45.8 bits (107), Expect = 1e-04
Identities = 23/56 (41%), Positives = 37/56 (66%), Gaps = 2/56 (3%)
Query: 521 QPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEE 576
Q + EEEE+ EE+++ +EEE EE+ E K++ + EE V +EEE++K K +E
Sbjct: 2240 QESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK--QVEKEEEEKKKKKKE 2293
Score = 44.7 bits (104), Expect = 2e-04
Identities = 26/78 (33%), Positives = 48/78 (61%), Gaps = 3/78 (3%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
+KQ S ++ + + + +EEEE +EEE+++ EEEEGEEK EK++ + ++ +
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEER-KEEEEGEEKQVEKEEEEKKKKKKEKKK 2296
Query: 566 EEEDRKPKA--EEDEILN 581
EE K + E++EI++
Sbjct: 2297 EEVQEKEEVFEEKEEIMS 2314
Score = 40.4 bits (93), Expect = 0.005
Identities = 19/67 (28%), Positives = 43/67 (64%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
+E +++ + + + + EEEE+ EE++ +EEEE +E+ E ++K +E+ +++E +K
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296
Query: 572 PKAEEDE 578
+ +E E
Sbjct: 2297 EEVQEKE 2303
Score = 38.9 bits (89), Expect = 0.013
Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 11/98 (11%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEE-----------EKEEEKDKGDEEEEGEEKLEEKQKS 554
K+ G + K+ + Q D E EE E E+++ EEEE E+ EE+++
Sbjct: 2201 KEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE 2260
Query: 555 DAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
+ E+ +EEE + + E++E + + K + E
Sbjct: 2261 EVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 7/69 (10%)
Query: 521 QPDVKEEEEEKEEEKDKGDEEEEG----EEKLEEKQKSDAEEDGGTVSQEE---EDRKPK 573
+ ++ +EE + EEK K EEEE EKL E++ A+E+ + ++E + ++
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791
Query: 574 AEEDEILNR 582
EE+E L R
Sbjct: 1792 PEEEERLGR 1800
Score = 32.0 bits (71), Expect = 1.6
Identities = 19/87 (21%), Positives = 43/87 (49%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
G+++ E ++ + + K+EE +++EE + EE EE+ E + EE+ ++
Sbjct: 2275 GEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334
Query: 565 QEEEDRKPKAEEDEILNRSPRNRKPRR 591
+E + K ++++ + RK R
Sbjct: 2335 EEVDREKEILKKEKQFKLQEQRRKSLR 2361
>gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]
Length = 111
Score = 46.6 bits (109), Expect = 6e-05
Identities = 28/65 (43%), Positives = 37/65 (56%), Gaps = 4/65 (6%)
Query: 518 DAPQPDVKEEEEEKEEEKDK--GDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDR--KPK 573
DAP E EE E+E D +EEEEG E+ EE+++ D EE+ G +E E K
Sbjct: 32 DAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRA 91
Query: 574 AEEDE 578
AE+DE
Sbjct: 92 AEDDE 96
Score = 39.7 bits (91), Expect = 0.008
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 6/72 (8%)
Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
+Q + E + + + +EEEEE + E++ GDE+EE E ++ D E+D +
Sbjct: 46 EQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDD------D 99
Query: 567 EEDRKPKAEEDE 578
+ +K K +ED+
Sbjct: 100 VDTKKQKTDEDD 111
Score = 33.9 bits (76), Expect = 0.43
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 7/63 (11%)
Query: 523 DVKEEEEEKEEEKDKGD-------EEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAE 575
D+KE++E EE ++ D E EE E+ + + + EE+GG +EEE+ + E
Sbjct: 16 DLKEKKEVVEEAENGRDAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEE 75
Query: 576 EDE 578
+ +
Sbjct: 76 DGD 78
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 46.2 bits (108), Expect = 8e-05
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
+++TS E ++ +EEEEE+EEE+++G EE EE+ EE+++ + EE G +
Sbjct: 261 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 318
Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
E + E+E+ R +
Sbjct: 319 ASEQSAEEVSEEEMSEDEERENE 341
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
S + S E K + A + +EEE+++ +EEEEG E+ EE+++ + EE+
Sbjct: 252 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 311
Query: 562 TVSQEEEDRKPKAEE 576
T S EE + AEE
Sbjct: 312 TGSNSEEASEQSAEE 326
Score = 38.5 bits (88), Expect = 0.018
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
SG E ++ + + EE EE+EEE++ +EEEE EE + AEE V
Sbjct: 274 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 327
Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
S+EE + E + L P +R R
Sbjct: 328 SEEEMSEDEERENENHLLVVPESRFDR 354
Score = 37.4 bits (85), Expect = 0.039
Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
ME + + D+ + E + + E G E+ EE+++ + EE+G T + EE+ +
Sbjct: 245 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 303
Query: 572 PKAEEDE 578
+ EE+E
Sbjct: 304 EEEEEEE 310
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
E E G EEEE EE+ EE++ S +EE S+EEE+ + + EE+ N + +
Sbjct: 268 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 322
Query: 589 PRRE 592
E
Sbjct: 323 SAEE 326
Score = 34.7 bits (78), Expect = 0.25
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)
Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
K +EEK EE+D + E G EE+++ + EE+ G+ S+E
Sbjct: 238 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 297
Query: 567 EEDRKPKAEEDE 578
E+ + + EE+E
Sbjct: 298 SEEEEEEEEEEE 309
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
E ++ + +EEEEE+EEE++ G EE EE++ E ++ + E V
Sbjct: 288 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 347
Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
+ DR + + E+E+ +P++
Sbjct: 348 PESRFDRDSGESEEAEEEVGEGTPQS 373
Score = 31.2 bits (69), Expect = 2.8
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%)
Query: 513 EYKKTDAPQPDVKEEEEEKE----EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEE 567
E +K VKE E E+ EE+DK E E +++ E ++ S E D + +
Sbjct: 103 EKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERK 162
Query: 568 EDRKPKAEEDEILNRSPRNRKPRRE 592
+R+ K E + R + R+ R E
Sbjct: 163 RERERKMREQQKEQREQKERERRAE 187
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 46.2 bits (108), Expect = 8e-05
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
+++TS E ++ +EEEEE+EEE+++G EE EE+ EE+++ + EE G +
Sbjct: 271 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 328
Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
E + E+E+ R +
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENE 351
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
S + S E K + A + +EEE+++ +EEEEG E+ EE+++ + EE+
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
Query: 562 TVSQEEEDRKPKAEE 576
T S EE + AEE
Sbjct: 322 TGSNSEEASEQSAEE 336
Score = 38.5 bits (88), Expect = 0.018
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
SG E ++ + + EE EE+EEE++ +EEEE EE + AEE V
Sbjct: 284 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 337
Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
S+EE + E + L P +R R
Sbjct: 338 SEEEMSEDEERENENHLLVVPESRFDR 364
Score = 37.4 bits (85), Expect = 0.039
Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
ME + + D+ + E + + E G E+ EE+++ + EE+G T + EE+ +
Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 313
Query: 572 PKAEEDE 578
+ EE+E
Sbjct: 314 EEEEEEE 320
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
E E G EEEE EE+ EE++ S +EE S+EEE+ + + EE+ N + +
Sbjct: 278 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 332
Query: 589 PRRE 592
E
Sbjct: 333 SAEE 336
Score = 34.7 bits (78), Expect = 0.25
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)
Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
K +EEK EE+D + E G EE+++ + EE+ G+ S+E
Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307
Query: 567 EEDRKPKAEEDE 578
E+ + + EE+E
Sbjct: 308 SEEEEEEEEEEE 319
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
E ++ + +EEEEE+EEE++ G EE EE++ E ++ + E V
Sbjct: 298 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 357
Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
+ DR + + E+E+ +P++
Sbjct: 358 PESRFDRDSGESEEAEEEVGEGTPQS 383
Score = 30.8 bits (68), Expect = 3.7
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 524 VKEEEEEKE----EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
VKE E E+ EE+DK E E +++ E ++ S E D + + +R+ K E +
Sbjct: 124 VKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ 183
Query: 579 ILNRSPRNRKPRRE 592
R + R+ R E
Sbjct: 184 KEQREQKERERRAE 197
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 46.2 bits (108), Expect = 8e-05
Identities = 27/70 (38%), Positives = 41/70 (58%), Gaps = 2/70 (2%)
Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDG--GTVSQEEEDRKPKAEEDEILNR 582
+EE EE+ EE+ +G+EE EGE + EE+ + + E +G G EEE+ + + EE E
Sbjct: 992 EEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGE 1051
Query: 583 SPRNRKPRRE 592
NR+ R E
Sbjct: 1052 GEENRRNREE 1061
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
Query: 513 EYKKTDAPQPDVKEEEE----EKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEE 568
E+KK D + + KE E+ E+ +E ++G EEE GE + EE + + EE G +E E
Sbjct: 701 EWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGE 760
Query: 569 DRKPKAEEDE 578
+ + E ++
Sbjct: 761 GEEVEGEREK 770
Score = 43.9 bits (102), Expect = 4e-04
Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGD-EEEEGEEKLEEKQKSDAEEDGGTV 563
G+++ G E + + + + E E E E E+ +G+ EEEEGEE+ EE++K E+
Sbjct: 999 GEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRN 1058
Query: 564 SQEEEDRKPKAEE 576
+EEE+ + K +E
Sbjct: 1059 REEEEEEEGKYQE 1071
Score = 43.1 bits (100), Expect = 7e-04
Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 10/76 (13%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGD--------EEEEGEEKLEEK--QKSDAEEDGGT 562
E+ + + + D +EEEE++ E K++G+ E+EEGE K EE+ ++ EE+G
Sbjct: 734 EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQ 793
Query: 563 VSQEEEDRKPKAEEDE 578
EEE+ + + EE E
Sbjct: 794 GEGEEEETEGRGEEKE 809
Score = 42.7 bits (99), Expect = 0.001
Identities = 24/73 (32%), Positives = 42/73 (57%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
K++ +E + + + + +EEEEE E E+++G+ EEE E EE+ + EE+G
Sbjct: 808 KEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG 867
Query: 566 EEEDRKPKAEEDE 578
EEE + + E +E
Sbjct: 868 EEEGEEGEGEGEE 880
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEE---EGEEKLEEKQKSDAEEDGG 561
G + G ++ + + + +EEE E EEE+ +G+EEE +GEE+ EE + + E+G
Sbjct: 816 GGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGE 875
Query: 562 TVSQEEEDRKPKAEEDE 578
+EEE EE E
Sbjct: 876 GEGEEEEGEGEGEEEGE 892
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 15/88 (17%)
Query: 506 KKQTSGMEYK-KTDAPQPDVKEEE-----EEKEE---------EKDKGDEEEEGEEKLEE 550
K++ +G E K + + Q + +EEE EEKEE E+ KG+ EEE EE E
Sbjct: 777 KEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGE 836
Query: 551 KQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
+++ + EE+ G +EE + K + E +E
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEE 864
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/67 (35%), Positives = 38/67 (56%)
Query: 511 GMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDR 570
G E + + + +E E E EEE+ +G+ EEEGE + EE++ E+ G EEE+
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917
Query: 571 KPKAEED 577
+ K EE+
Sbjct: 918 EGKGEEE 924
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/56 (44%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 526 EEEE---EKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
EEEE E EEE+ +G+ EEEGE + EE + EE+G +EEE + EE E
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004
Score = 41.6 bits (96), Expect = 0.002
Identities = 26/80 (32%), Positives = 46/80 (57%), Gaps = 6/80 (7%)
Query: 505 GKKQTSGMEYK-KTDAPQPDVKEEE-----EEKEEEKDKGDEEEEGEEKLEEKQKSDAEE 558
GK++ G E + + + + + K+EE E+ EEE D+G+ EEE E E+++ E
Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814
Query: 559 DGGTVSQEEEDRKPKAEEDE 578
+GG V + + +R+ + EE E
Sbjct: 815 EGGEVEEGKGEREEEEEEGE 834
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/72 (29%), Positives = 40/72 (55%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
G+++ G + + + + + EEEE EEE ++ ++E EGEE +++ + EE +
Sbjct: 1013 GEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072
Query: 565 QEEEDRKPKAEE 576
EEE+ + EE
Sbjct: 1073 GEEENERQDGEE 1084
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/74 (31%), Positives = 39/74 (52%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
G+++ E KK + + K EEE + E ++ + E GEEK E + E + G
Sbjct: 766 GEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGE 825
Query: 565 QEEEDRKPKAEEDE 578
+EEE+ + + EE+E
Sbjct: 826 REEEEEEGEGEEEE 839
Score = 40.8 bits (94), Expect = 0.004
Identities = 24/72 (33%), Positives = 39/72 (54%)
Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
++ G E + + + +E E E EEE + EEEEGE + EE+ + + EE+ G E
Sbjct: 863 EEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE 922
Query: 567 EEDRKPKAEEDE 578
EE + + E +E
Sbjct: 923 EEGEEGEGEGEE 934
Score = 40.4 bits (93), Expect = 0.005
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 3/72 (4%)
Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEE--EKDKGD-EEEEGEEKLEEKQKSDAEEDGGTV 563
K+ G E ++ + Q KE +E EE E++ G+ EEEEG+ + EE+++ + +E+G
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE 762
Query: 564 SQEEEDRKPKAE 575
E E K + E
Sbjct: 763 EVEGEREKEEGE 774
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/71 (38%), Positives = 41/71 (57%), Gaps = 10/71 (14%)
Query: 526 EEEEEKEEE-KDKGDEEEEGEEKLE---EKQKSDAEEDGGTVSQEEEDRKPKAEEDEILN 581
EEE E EEE + +G+EEEEGE + E E+ + + EE+ G EE +++ + EE+
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENR--- 1056
Query: 582 RSPRNRKPRRE 592
RNR+ E
Sbjct: 1057 ---RNREEEEE 1064
Score = 39.7 bits (91), Expect = 0.008
Identities = 26/76 (34%), Positives = 45/76 (59%), Gaps = 7/76 (9%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEK---EEEKDKGD-EEEEGEEKLEEKQKSDAEEDGG 561
+++T G +K + + + E EE K EEE+++G+ EEEEGE E+++ + EE+ G
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE---GEEEEGEGEEEEG 854
Query: 562 TVSQEEEDRKPKAEED 577
EEE + + EE+
Sbjct: 855 EGKGEEEGEEGEGEEE 870
Score = 38.9 bits (89), Expect = 0.013
Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGD-EEEEGEEKLEEKQKSDAEEDGGTVS 564
+++ G E + + + +E E E+E E+ +G+ EEEEGE + EE+ + + EE+ G
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903
Query: 565 QEEEDRKPKAEED 577
EEE EE+
Sbjct: 904 GEEEGEGEGEEEE 916
Score = 38.5 bits (88), Expect = 0.018
Identities = 20/53 (37%), Positives = 32/53 (60%)
Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
E EEE E E ++G+ E E EE E ++ + EE+G + EE+ + + EE+E
Sbjct: 965 EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017
Score = 38.1 bits (87), Expect = 0.023
Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 3/57 (5%)
Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQ---KSDAEEDGGTVSQEEEDRKPKAEEDE 578
+E E E EEE+ +G+ EEEGE + EE++ K + E + G EEE+ + + E+ E
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGE 945
Score = 38.1 bits (87), Expect = 0.023
Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Query: 526 EEEEEKEEEKDKGD-EEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
EEE E E E+ +G+ EEEEGE + EE++ + E+ G +E E + EE E+
Sbjct: 967 EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV 1021
Score = 37.7 bits (86), Expect = 0.030
Identities = 23/53 (43%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 526 EEEEEKEEEKDKGDEE-EEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
E E E+EE + KG+EE EEGE + EE++ EDG +EEE EE+
Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961
Score = 37.7 bits (86), Expect = 0.030
Identities = 21/52 (40%), Positives = 31/52 (59%)
Query: 527 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
E E +EEE + EEEEGE + EE+ + + EE G +EE + + + EE E
Sbjct: 945 EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996
Score = 37.4 bits (85), Expect = 0.039
Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 8/81 (9%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGD-EEEEGE-EKLEEKQKSDAEEDG--- 560
+++ G ++ + + + +EEE E E E +G+ EEEEGE E EE+ + + EE+G
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973
Query: 561 ---GTVSQEEEDRKPKAEEDE 578
G EEE+ + + EE+E
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEE 994
Score = 37.0 bits (84), Expect = 0.051
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGD---EEEEGEEKLEEKQKSDAEEDGG 561
G+++ E ++ + + +E E + EEE ++G+ EEEEGE + E+ + EE+G
Sbjct: 895 GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE 954
Query: 562 TVSQEEEDRKPKAEEDE 578
+EEE EE E
Sbjct: 955 WEGEEEEGEGEGEEEGE 971
Score = 36.6 bits (83), Expect = 0.067
Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGE-EKLEEKQKSDAEEDGGTV 563
G+++ E ++ + + + + + EE+ EE + +E EEGE E EE+ + + EE+G
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894
Query: 564 SQEEEDRKPKAEEDE 578
+EEE EE E
Sbjct: 895 GEEEEGEGEGEEEGE 909
Score = 36.6 bits (83), Expect = 0.067
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 7/81 (8%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEK------EEEKDKGDEEE-EGEEKLEEKQKSDAE 557
GK + G E + + + E EEE+ EE + +G+EEE EGE + E + + + E
Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915
Query: 558 EDGGTVSQEEEDRKPKAEEDE 578
E G +E E+ + + EE+E
Sbjct: 916 EGEGKGEEEGEEGEGEGEEEE 936
Score = 36.2 bits (82), Expect = 0.087
Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
K++ G + ++ + +EE E EEE+ +EEEE E E K++ + EE G +
Sbjct: 713 KEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEG--EGKEEGEGEEVEGEREK 770
Query: 566 EEEDRK 571
EE +RK
Sbjct: 771 EEGERK 776
Score = 36.2 bits (82), Expect = 0.087
Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 3/77 (3%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEK-EEEKDKGDEEEEGEEKLEEKQKSDAEEDG--G 561
G+ + G + + + + +EE E + EEE+ +G EEEGEE E ++ + E +G G
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 562 TVSQEEEDRKPKAEEDE 578
EEE+ + + EE+E
Sbjct: 945 EGEGEEEEGEWEGEEEE 961
Score = 35.8 bits (81), Expect = 0.11
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 5/77 (6%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKS---DAEEDGG 561
G+++ E ++ + + +E E E EEE + EEEEGE K EE+ + + EE+ G
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937
Query: 562 TVSQEEEDRKPKAEEDE 578
E ED + + EE+E
Sbjct: 938 --EGEGEDGEGEGEEEE 952
Score = 34.7 bits (78), Expect = 0.25
Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 10/83 (12%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEK-------DKGDEE---EEGEEKLEEKQKSD 555
+++ G ++ + + + + E+EE E +K +KG+EE EGEE+ E + +
Sbjct: 748 EEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807
Query: 556 AEEDGGTVSQEEEDRKPKAEEDE 578
EE G E E+ K + EE+E
Sbjct: 808 KEEGGEVEGGEVEEGKGEREEEE 830
Score = 33.9 bits (76), Expect = 0.43
Identities = 20/76 (26%), Positives = 41/76 (53%), Gaps = 3/76 (3%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEE--EKDKGDEEEEGEEK-LEEKQKSDAEEDGG 561
G+K E ++ + ++ E+EE K+ E+ + E E+G +K ++ + EE+ G
Sbjct: 677 GEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG 736
Query: 562 TVSQEEEDRKPKAEED 577
+EE DR+ + E++
Sbjct: 737 EGEEEEGDREEEEEKE 752
Score = 33.9 bits (76), Expect = 0.43
Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 3/77 (3%)
Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEE-EKDKGDEEEEGEEKLE--EKQKSDAEEDGG 561
G+ + G K+ + K + EE+E+ E+++G ++E +E E E++ + EE+ G
Sbjct: 684 GEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEG 743
Query: 562 TVSQEEEDRKPKAEEDE 578
+EEE EE E
Sbjct: 744 DREEEEEKEGEGKEEGE 760
Score = 33.9 bits (76), Expect = 0.43
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 5/70 (7%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLE-----EKQKSDAEEDGGTVSQEE 567
E ++ + D + E EE+E E + +EE EGE + E E+ + + EE+ G EE
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992
Query: 568 EDRKPKAEED 577
E+ + + EE+
Sbjct: 993 EEGEEEGEEE 1002
Score = 31.6 bits (70), Expect = 2.1
Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 3/55 (5%)
Query: 526 EEEEEKEEEKDKGDEEE--EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
EE E+ E++K +G+ E EGE++L EK++ + DG Q+E ++ + E ++
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEW-KKRDGEEQEQKEREQGHQKERNQ 725
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 46.2 bits (108), Expect = 8e-05
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
+++TS E ++ +EEEEE+EEE+++G EE EE+ EE+++ + EE G +
Sbjct: 262 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 319
Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
E + E+E+ R +
Sbjct: 320 ASEQSAEEVSEEEMSEDEERENE 342
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
S + S E K + A + +EEE+++ +EEEEG E+ EE+++ + EE+
Sbjct: 253 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 312
Query: 562 TVSQEEEDRKPKAEE 576
T S EE + AEE
Sbjct: 313 TGSNSEEASEQSAEE 327
Score = 38.5 bits (88), Expect = 0.018
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
SG E ++ + + EE EE+EEE++ +EEEE EE + AEE V
Sbjct: 275 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 328
Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
S+EE + E + L P +R R
Sbjct: 329 SEEEMSEDEERENENHLLVVPESRFDR 355
Score = 37.4 bits (85), Expect = 0.039
Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
ME + + D+ + E + + E G E+ EE+++ + EE+G T + EE+ +
Sbjct: 246 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 304
Query: 572 PKAEEDE 578
+ EE+E
Sbjct: 305 EEEEEEE 311
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
E E G EEEE EE+ EE++ S +EE S+EEE+ + + EE+ N + +
Sbjct: 269 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 323
Query: 589 PRRE 592
E
Sbjct: 324 SAEE 327
Score = 34.7 bits (78), Expect = 0.25
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)
Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
K +EEK EE+D + E G EE+++ + EE+ G+ S+E
Sbjct: 239 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 298
Query: 567 EEDRKPKAEEDE 578
E+ + + EE+E
Sbjct: 299 SEEEEEEEEEEE 310
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
E ++ + +EEEEE+EEE++ G EE EE++ E ++ + E V
Sbjct: 289 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 348
Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
+ DR + + E+E+ +P++
Sbjct: 349 PESRFDRDSGESEEAEEEVGEGTPQS 374
Score = 32.3 bits (72), Expect = 1.3
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 7/85 (8%)
Query: 515 KKTDAPQPDVKEEEEEKE------EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEE 567
K+ + VKE+E E E EE+DK E E +++ E ++ S E D + +
Sbjct: 104 KRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERK 163
Query: 568 EDRKPKAEEDEILNRSPRNRKPRRE 592
+R+ K E + R + R+ R E
Sbjct: 164 RERERKMREQQKEQREQKERERRAE 188
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 46.2 bits (108), Expect = 8e-05
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
+++TS E ++ +EEEEE+EEE+++G EE EE+ EE+++ + EE G +
Sbjct: 271 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 328
Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
E + E+E+ R +
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENE 351
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
S + S E K + A + +EEE+++ +EEEEG E+ EE+++ + EE+
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321
Query: 562 TVSQEEEDRKPKAEE 576
T S EE + AEE
Sbjct: 322 TGSNSEEASEQSAEE 336
Score = 38.5 bits (88), Expect = 0.018
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
SG E ++ + + EE EE+EEE++ +EEEE EE + AEE V
Sbjct: 284 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 337
Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
S+EE + E + L P +R R
Sbjct: 338 SEEEMSEDEERENENHLLVVPESRFDR 364
Score = 37.4 bits (85), Expect = 0.039
Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
ME + + D+ + E + + E G E+ EE+++ + EE+G T + EE+ +
Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 313
Query: 572 PKAEEDE 578
+ EE+E
Sbjct: 314 EEEEEEE 320
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
E E G EEEE EE+ EE++ S +EE S+EEE+ + + EE+ N + +
Sbjct: 278 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 332
Query: 589 PRRE 592
E
Sbjct: 333 SAEE 336
Score = 34.7 bits (78), Expect = 0.25
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)
Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
K +EEK EE+D + E G EE+++ + EE+ G+ S+E
Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307
Query: 567 EEDRKPKAEEDE 578
E+ + + EE+E
Sbjct: 308 SEEEEEEEEEEE 319
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
E ++ + +EEEEE+EEE++ G EE EE++ E ++ + E V
Sbjct: 298 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 357
Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
+ DR + + E+E+ +P++
Sbjct: 358 PESRFDRDSGESEEAEEEVGEGTPQS 383
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 46.2 bits (108), Expect = 8e-05
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
+++TS E ++ +EEEEE+EEE+++G EE EE+ EE+++ + EE G +
Sbjct: 239 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 296
Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
E + E+E+ R +
Sbjct: 297 ASEQSAEEVSEEEMSEDEERENE 319
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
S + S E K + A + +EEE+++ +EEEEG E+ EE+++ + EE+
Sbjct: 230 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 289
Query: 562 TVSQEEEDRKPKAEE 576
T S EE + AEE
Sbjct: 290 TGSNSEEASEQSAEE 304
Score = 38.5 bits (88), Expect = 0.018
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
SG E ++ + + EE EE+EEE++ +EEEE EE + AEE V
Sbjct: 252 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 305
Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
S+EE + E + L P +R R
Sbjct: 306 SEEEMSEDEERENENHLLVVPESRFDR 332
Score = 37.4 bits (85), Expect = 0.039
Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
ME + + D+ + E + + E G E+ EE+++ + EE+G T + EE+ +
Sbjct: 223 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 281
Query: 572 PKAEEDE 578
+ EE+E
Sbjct: 282 EEEEEEE 288
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
E E G EEEE EE+ EE++ S +EE S+EEE+ + + EE+ N + +
Sbjct: 246 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 300
Query: 589 PRRE 592
E
Sbjct: 301 SAEE 304
Score = 34.7 bits (78), Expect = 0.25
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)
Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
K +EEK EE+D + E G EE+++ + EE+ G+ S+E
Sbjct: 216 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 275
Query: 567 EEDRKPKAEEDE 578
E+ + + EE+E
Sbjct: 276 SEEEEEEEEEEE 287
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
E ++ + +EEEEE+EEE++ G EE EE++ E ++ + E V
Sbjct: 266 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 325
Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
+ DR + + E+E+ +P++
Sbjct: 326 PESRFDRDSGESEEAEEEVGEGTPQS 351
Score = 31.2 bits (69), Expect = 2.8
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 524 VKEEEEEKE------EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEEEDRKPKAEE 576
VKE+E E E EE+DK E E +++ E ++ S E D + + +R+ K E
Sbjct: 90 VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 149
Query: 577 DEILNRSPRNRKPRRE 592
+ R + R+ R E
Sbjct: 150 QQKEQREQKERERRAE 165
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 46.2 bits (108), Expect = 8e-05
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
+++TS E ++ +EEEEE+EEE+++G EE EE+ EE+++ + EE G +
Sbjct: 228 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 285
Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
E + E+E+ R +
Sbjct: 286 ASEQSAEEVSEEEMSEDEERENE 308
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
S + S E K + A + +EEE+++ +EEEEG E+ EE+++ + EE+
Sbjct: 219 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 278
Query: 562 TVSQEEEDRKPKAEE 576
T S EE + AEE
Sbjct: 279 TGSNSEEASEQSAEE 293
Score = 38.5 bits (88), Expect = 0.018
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
SG E ++ + + EE EE+EEE++ +EEEE EE + AEE V
Sbjct: 241 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 294
Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
S+EE + E + L P +R R
Sbjct: 295 SEEEMSEDEERENENHLLVVPESRFDR 321
Score = 37.4 bits (85), Expect = 0.039
Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
ME + + D+ + E + + E G E+ EE+++ + EE+G T + EE+ +
Sbjct: 212 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 270
Query: 572 PKAEEDE 578
+ EE+E
Sbjct: 271 EEEEEEE 277
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
E E G EEEE EE+ EE++ S +EE S+EEE+ + + EE+ N + +
Sbjct: 235 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 289
Query: 589 PRRE 592
E
Sbjct: 290 SAEE 293
Score = 34.7 bits (78), Expect = 0.25
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)
Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
K +EEK EE+D + E G EE+++ + EE+ G+ S+E
Sbjct: 205 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 264
Query: 567 EEDRKPKAEEDE 578
E+ + + EE+E
Sbjct: 265 SEEEEEEEEEEE 276
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
E ++ + +EEEEE+EEE++ G EE EE++ E ++ + E V
Sbjct: 255 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 314
Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
+ DR + + E+E+ +P++
Sbjct: 315 PESRFDRDSGESEEAEEEVGEGTPQS 340
Score = 32.3 bits (72), Expect = 1.3
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 7/85 (8%)
Query: 515 KKTDAPQPDVKEEEEEKE------EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEE 567
K+ + VKE+E E E EE+DK E E +++ E ++ S E D + +
Sbjct: 70 KRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERK 129
Query: 568 EDRKPKAEEDEILNRSPRNRKPRRE 592
+R+ K E + R + R+ R E
Sbjct: 130 RERERKMREQQKEQREQKERERRAE 154
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 46.2 bits (108), Expect = 8e-05
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
+++TS E ++ +EEEEE+EEE+++G EE EE+ EE+++ + EE G +
Sbjct: 17 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 74
Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
E + E+E+ R +
Sbjct: 75 ASEQSAEEVSEEEMSEDEERENE 97
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
S + S E K + A + +EEE+++ +EEEEG E+ EE+++ + EE+
Sbjct: 8 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 67
Query: 562 TVSQEEEDRKPKAEE 576
T S EE + AEE
Sbjct: 68 TGSNSEEASEQSAEE 82
Score = 38.5 bits (88), Expect = 0.018
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)
Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
SG E ++ + + EE EE+EEE++ +EEEE EE + AEE V
Sbjct: 30 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 83
Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
S+EE + E + L P +R R
Sbjct: 84 SEEEMSEDEERENENHLLVVPESRFDR 110
Score = 37.4 bits (85), Expect = 0.039
Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
ME + + D+ + E + + E G E+ EE+++ + EE+G T + EE+ +
Sbjct: 1 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 59
Query: 572 PKAEEDE 578
+ EE+E
Sbjct: 60 EEEEEEE 66
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
E E G EEEE EE+ EE++ S +EE S+EEE+ + + EE+ N + +
Sbjct: 24 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 78
Query: 589 PRRE 592
E
Sbjct: 79 SAEE 82
Score = 32.7 bits (73), Expect = 0.96
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)
Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
E ++ + +EEEEE+EEE++ G EE EE++ E ++ + E V
Sbjct: 44 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 103
Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
+ DR + + E+E+ +P++
Sbjct: 104 PESRFDRDSGESEEAEEEVGEGTPQS 129
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,098,096
Number of Sequences: 37866
Number of extensions: 1695441
Number of successful extensions: 37698
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 685
Number of HSP's successfully gapped in prelim test: 407
Number of HSP's that attempted gapping in prelim test: 12463
Number of HSP's gapped (non-prelim): 12707
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.