Guide to the Human Genome
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Search of human proteins with 66933005

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|66933005 calnexin precursor [Homo sapiens]
         (592 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66933005 calnexin precursor [Homo sapiens]                        1249   0.0  
gi|10716563 calnexin precursor [Homo sapiens]                        1249   0.0  
gi|194578888 calmegin [Homo sapiens]                                  725   0.0  
gi|4758004 calmegin [Homo sapiens]                                    725   0.0  
gi|4757900 calreticulin precursor [Homo sapiens]                      275   9e-74
gi|187608348 calreticulin 3 [Homo sapiens]                            138   2e-32
gi|17975763 myelin transcription factor 1 [Homo sapiens]               52   1e-06
gi|28274705 family with sequence similarity 9, member A [Homo sa...    51   3e-06
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     50   8e-06
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    49   1e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    49   2e-05
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          49   2e-05
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            48   3e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        48   3e-05
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    48   3e-05
gi|21361639 DIPB protein [Homo sapiens]                                47   4e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    47   4e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    47   4e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    47   4e-05
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    47   5e-05
gi|221219020 NYD-SP11 protein [Homo sapiens]                           47   6e-05
gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]               47   6e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     46   8e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     46   8e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    46   8e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   8e-05
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   8e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   8e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   8e-05
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    46   8e-05

>gi|66933005 calnexin precursor [Homo sapiens]
          Length = 592

 Score = 1249 bits (3232), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY 60
           MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
Sbjct: 1   MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY 60

Query: 61  KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL 120
           KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
Sbjct: 61  KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL 120

Query: 121 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH 180
           VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
Sbjct: 121 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH 180

Query: 181 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL 240
           DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
Sbjct: 181 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL 240

Query: 241 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK 300
           ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
Sbjct: 241 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK 300

Query: 301 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360
           PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
Sbjct: 301 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360

Query: 361 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS 420
           ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
Sbjct: 361 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS 420

Query: 421 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER 480
           AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
Sbjct: 421 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER 480

Query: 481 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE 540
           PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
Sbjct: 481 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE 540

Query: 541 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
           EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
Sbjct: 541 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592


>gi|10716563 calnexin precursor [Homo sapiens]
          Length = 592

 Score = 1249 bits (3232), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY 60
           MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY
Sbjct: 1   MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTY 60

Query: 61  KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL 120
           KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL
Sbjct: 61  KAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGL 120

Query: 121 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH 180
           VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
Sbjct: 121 VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH 180

Query: 181 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL 240
           DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL
Sbjct: 181 DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTL 240

Query: 241 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK 300
           ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK
Sbjct: 241 ILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVK 300

Query: 301 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360
           PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC
Sbjct: 301 PDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360

Query: 361 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS 420
           ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS
Sbjct: 361 ESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFS 420

Query: 421 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER 480
           AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER
Sbjct: 421 AIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEER 480

Query: 481 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE 540
           PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE
Sbjct: 481 PWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDE 540

Query: 541 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
           EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
Sbjct: 541 EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592


>gi|194578888 calmegin [Homo sapiens]
          Length = 610

 Score =  725 bits (1871), Expect = 0.0
 Identities = 340/586 (58%), Positives = 434/586 (74%), Gaps = 25/586 (4%)

Query: 11  LVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVY 70
           L LG   +  +    DD ++ ED  ++  EE++ ++ +      S ++ YK P P GEVY
Sbjct: 8   LCLGLLFISINAEFMDDDVETED-FEENSEEIDVNESEL-----SSEIKYKTPQPIGEVY 61

Query: 71  FADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHA 130
           FA++FD G L+GW+LSKAKKDD D+EI+ YDG+WE+EE+KE+++PGD+GLVL SRAKHHA
Sbjct: 62  FAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHA 121

Query: 131 ISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFG 190
           ISA L KPF+F  KPLIVQYEVNFQ+GI+CGGAY+KLL+ T +L L+ F+DKT Y IMFG
Sbjct: 122 ISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMFG 181

Query: 191 PDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEI 250
           PDKCGEDYKLHFIFRHK+PKTG++EEKHAK PD DLK +FTD+KTHLYTL++NPD++FE+
Sbjct: 182 PDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEV 241

Query: 251 LVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPA 310
           LVDQ+VVN G+LL D+ PP+ P +EIEDP D+KPE+WDER KIPDP AVKP+DWDE  PA
Sbjct: 242 LVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPA 301

Query: 311 KIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQ 370
           +I D    KP GWLDDEP+++PDP+AEKP+DW+ED DGEWEAPQI NP C    GCG W+
Sbjct: 302 QIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRI--GCGEWK 359

Query: 371 RPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMT 430
            P+IDNP YKG W+PP++DNP+YQGIW PRKIPNPD+FED  PF +T FSA+GLELWSMT
Sbjct: 360 PPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMT 419

Query: 431 SDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILT 490
           SDI+FDNFIIC+++ + D WA DGW  K     A +PGV+ Q++ AAE  PWLW++Y++T
Sbjct: 420 SDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVT 479

Query: 491 VALPVFLVILFCC--SGKKQTSGMEYKKTDAPQPDVK-----EEEEEK---------EEE 534
             +P+ L+  FC     KK+    EYKKTD   P  K     EE+EEK         EEE
Sbjct: 480 AGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEE 539

Query: 535 KDKGDEEE-EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
           K + D E  E EE+ E ++KS+ E +     +E         EDE+
Sbjct: 540 KKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEM 585


>gi|4758004 calmegin [Homo sapiens]
          Length = 610

 Score =  725 bits (1871), Expect = 0.0
 Identities = 340/586 (58%), Positives = 434/586 (74%), Gaps = 25/586 (4%)

Query: 11  LVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVY 70
           L LG   +  +    DD ++ ED  ++  EE++ ++ +      S ++ YK P P GEVY
Sbjct: 8   LCLGLLFISINAEFMDDDVETED-FEENSEEIDVNESEL-----SSEIKYKTPQPIGEVY 61

Query: 71  FADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHA 130
           FA++FD G L+GW+LSKAKKDD D+EI+ YDG+WE+EE+KE+++PGD+GLVL SRAKHHA
Sbjct: 62  FAETFDSGRLAGWVLSKAKKDDMDEEISIYDGRWEIEELKENQVPGDRGLVLKSRAKHHA 121

Query: 131 ISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFG 190
           ISA L KPF+F  KPLIVQYEVNFQ+GI+CGGAY+KLL+ T +L L+ F+DKT Y IMFG
Sbjct: 122 ISAVLAKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTDDLILENFYDKTSYIIMFG 181

Query: 191 PDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEI 250
           PDKCGEDYKLHFIFRHK+PKTG++EEKHAK PD DLK +FTD+KTHLYTL++NPD++FE+
Sbjct: 182 PDKCGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKKFFTDRKTHLYTLVMNPDDTFEV 241

Query: 251 LVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPA 310
           LVDQ+VVN G+LL D+ PP+ P +EIEDP D+KPE+WDER KIPDP AVKP+DWDE  PA
Sbjct: 242 LVDQTVVNKGSLLEDVVPPIKPPKEIEDPNDKKPEEWDERAKIPDPSAVKPEDWDESEPA 301

Query: 311 KIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQ 370
           +I D    KP GWLDDEP+++PDP+AEKP+DW+ED DGEWEAPQI NP C    GCG W+
Sbjct: 302 QIEDSSVVKPAGWLDDEPKFIPDPNAEKPDDWNEDTDGEWEAPQILNPACRI--GCGEWK 359

Query: 371 RPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMT 430
            P+IDNP YKG W+PP++DNP+YQGIW PRKIPNPD+FED  PF +T FSA+GLELWSMT
Sbjct: 360 PPMIDNPKYKGVWRPPLVDNPNYQGIWSPRKIPNPDYFEDDHPFLLTSFSALGLELWSMT 419

Query: 431 SDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILT 490
           SDI+FDNFIIC+++ + D WA DGW  K     A +PGV+ Q++ AAE  PWLW++Y++T
Sbjct: 420 SDIYFDNFIICSEKEVADHWAADGWRWKIMIANANKPGVLKQLMAAAEGHPWLWLIYLVT 479

Query: 491 VALPVFLVILFCC--SGKKQTSGMEYKKTDAPQPDVK-----EEEEEK---------EEE 534
             +P+ L+  FC     KK+    EYKKTD   P  K     EE+EEK         EEE
Sbjct: 480 AGVPIALITSFCWPRKVKKKHKDTEYKKTDICIPQTKGVLEQEEKEEKAALEKPMDLEEE 539

Query: 535 KDKGDEEE-EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
           K + D E  E EE+ E ++KS+ E +     +E         EDE+
Sbjct: 540 KKQNDGEMLEKEEESEPEEKSEEEIEIIEGQEESNQSNKSGSEDEM 585


>gi|4757900 calreticulin precursor [Homo sapiens]
          Length = 417

 Score =  275 bits (703), Expect = 9e-74
 Identities = 176/503 (34%), Positives = 246/503 (48%), Gaps = 112/503 (22%)

Query: 69  VYFADSF--DRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRA 126
           VYF + F    G  S WI SK K D    +     GK+  +E K      DKGL     A
Sbjct: 21  VYFKEQFLDGDGWTSRWIESKHKSDF--GKFVLSSGKFYGDEEK------DKGLQTSQDA 72

Query: 127 KHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYT 186
           + +A+SA   +PF    + L+VQ+ V  +  I+CGG YVKL   +  L+    H  + Y 
Sbjct: 73  RFYALSASF-EPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNS--LDQTDMHGDSEYN 129

Query: 187 IMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPD 245
           IMFGPD CG   K +H IF +K     I ++   K           D+ THLYTLI+ PD
Sbjct: 130 IMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCK----------DDEFTHLYTLIVRPD 179

Query: 246 NSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERP--KIPDPEAVKPDD 303
           N++E+ +D S V SG+L                      +DWD  P  KI DP+A KP+D
Sbjct: 180 NTYEVKIDNSQVESGSL---------------------EDDWDFLPPKKIKDPDASKPED 218

Query: 304 WDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESA 363
           WDE A  KI D   +KPE W  D+PE++PDPDA+KPEDWDE+MDGEWE P          
Sbjct: 219 WDERA--KIDDPTDSKPEDW--DKPEHIPDPDAKKPEDWDEEMDGEWEPP---------- 264

Query: 364 PGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIG 423
                    VI NP YKG+WKP  IDNP Y+G W   +I NP++  D   +    F  +G
Sbjct: 265 ---------VIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLG 315

Query: 424 LELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWL 483
           L+LW + S   FDNF+I  D    +++ N+ WG+ KAA+         QM +  +E    
Sbjct: 316 LDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEK--------QMKDKQDEE--- 364

Query: 484 WVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEE 543
                                          ++    + D K +EEE+ E+K+  ++++E
Sbjct: 365 -------------------------------QRLKEEEEDKKRKEEEEAEDKEDDEDKDE 393

Query: 544 GEEKLEEKQKSDAEEDGGTVSQE 566
            EE  E+K++ + E+  G    E
Sbjct: 394 DEEDEEDKEEDEEEDVPGQAKDE 416



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 25/68 (36%), Positives = 42/68 (61%), Gaps = 5/68 (7%)

Query: 517 TDAPQPDVKEEEEE----KEEEKDKG-DEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
           T A +  +K++++E    KEEE+DK   EEEE E+K +++ K + EED     ++EE+  
Sbjct: 350 TKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDV 409

Query: 572 PKAEEDEI 579
           P   +DE+
Sbjct: 410 PGQAKDEL 417



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 5/47 (10%)

Query: 536 DKGDEEEEGEE-----KLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
           D+   EE G E     K  EKQ  D +++   + +EEED+K K EE+
Sbjct: 335 DEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEE 381


>gi|187608348 calreticulin 3 [Homo sapiens]
          Length = 384

 Score =  138 bits (347), Expect = 2e-32
 Identities = 101/354 (28%), Positives = 150/354 (42%), Gaps = 84/354 (23%)

Query: 117 DKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNL 176
           DKGL      + +AISA+  KPF    K L++QY V  +  ++CGG Y+K+     +++ 
Sbjct: 63  DKGLQTTQNGRFYAISARF-KPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPA--DIDQ 119

Query: 177 DQFHDKTPYTIMFGPDKCGEDYK-LHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKT 235
              + K+ Y IMFGPD CG D K +H I   KN     +E K   R   D         T
Sbjct: 120 KNLNGKSQYYIMFGPDICGFDIKKVHVILHFKNK---YHENKKLIRCKVD-------GFT 169

Query: 236 HLYTLILNPDNSFEILVDQSVVNSGNL-----LNDMTPPVNP--SREIEDPEDRKPEDWD 288
           HLYTLIL PD S+++ +D   + SG++     L  +    +P  S++ E  +D K +DW+
Sbjct: 170 HLYTLILRPDLSYDVKIDGQSIESGSIEYDWNLTSLKKETSPAESKDWEQTKDNKAQDWE 229

Query: 289 ERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDG 348
           +     D    K  DW+ D                                      +DG
Sbjct: 230 KH--FLDASTSKQSDWNGD--------------------------------------LDG 249

Query: 349 EWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFF 408
           +W A                   P++  P Y+   KP  I    ++ +W  RK+ N D+ 
Sbjct: 250 DWPA-------------------PMLQKPPYQDGLKPEGI----HKDVWLHRKMKNTDYL 286

Query: 409 EDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAAD 462
              +        AIGLELW + S   FDNF+I  D    D++    WG  K  +
Sbjct: 287 TQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYADNFGKATWGETKGPE 340


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 46/130 (35%), Positives = 68/130 (52%), Gaps = 22/130 (16%)

Query: 457 LKKAADGAA-EPGVVGQMI--EAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSGME 513
           L++AA+GAA E G  G  I  E AEE     VV + T           C    +  +  E
Sbjct: 198 LQEAAEGAASEEGEKGLFIQPEDAEE-----VVEVTTERSQDL-----CPQSLEDAASEE 247

Query: 514 YKKTDA----PQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEED 569
             K        + D +EEEEE+EEE+D+ +EEEE EE+ EE+++ + EE+     +EEE+
Sbjct: 248 SSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE-----EEEEE 302

Query: 570 RKPKAEEDEI 579
            + +A  D I
Sbjct: 303 EEEEAAPDVI 312



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 18/68 (26%), Positives = 35/68 (51%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
           E ++ +  + + +EEEEE+EEE+++ +EEE   + + ++  S          +  E   P
Sbjct: 277 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSP 336

Query: 573 KAEEDEIL 580
           K E   I+
Sbjct: 337 KPEYSVIV 344


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 26/56 (46%), Positives = 39/56 (69%), Gaps = 2/56 (3%)

Query: 526 EEEEEKEEEKDKGDEEEEGEEK--LEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
           EEEEEKEEE++K +EEEEGEE+   EE ++     +G    +EEE+ + + EE++I
Sbjct: 222 EEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQI 277



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 21/51 (41%), Positives = 35/51 (68%)

Query: 528 EEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           E+E+EEEK++ +E+EE EE+ EE+   +  E+GG   + EE  + + EE+E
Sbjct: 220 EDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEE 270



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 21/52 (40%), Positives = 34/52 (65%)

Query: 527 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           E+EE+EE++++ ++EEE EE  EE    + EE GG    EE + + + EE+E
Sbjct: 220 EDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEE 271



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 6/84 (7%)

Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEE------EGEEKLEEKQKSDAEEDGGTVSQEEE 568
           ++ +  + + KEEEEE+ EE+  G+E E      EGEE  EE+++ + EE+   +   +E
Sbjct: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282

Query: 569 DRKPKAEEDEILNRSPRNRKPRRE 592
            +K   +   + +   R  KP  E
Sbjct: 283 KQKRWQQPTGVRSWRLREMKPLLE 306



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
           G+++  G E ++        + EEEE+EEE+   +EEEE  +  +EKQK   ++  G  S
Sbjct: 240 GEEEGGGEEGEEGGGGGEGEETEEEEEEEEE---EEEEEQIKAFQEKQKR-WQQPTGVRS 295

Query: 565 QEEEDRKPKAEE 576
               + KP  E+
Sbjct: 296 WRLREMKPLLEQ 307


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 3/73 (4%)

Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEE---EGEEKLEEKQKSDAEEDGGTV 563
           K+    E KK +  +   ++EEEE+EE K K +EEE   + EE+ E K + D +EDGG  
Sbjct: 374 KEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQK 433

Query: 564 SQEEEDRKPKAEE 576
            + E  + P  EE
Sbjct: 434 PEGEPQQDPGTEE 446



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 30/66 (45%), Positives = 43/66 (65%), Gaps = 5/66 (7%)

Query: 515 KKTDAPQPDVKEEEEE--KEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
           K+  A Q ++KE+EEE  K+EE+ K  EE+E EE+ E KQK + EE     ++ EE+ + 
Sbjct: 364 KRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEE---IRNKNEEEGES 420

Query: 573 KAEEDE 578
           K EEDE
Sbjct: 421 KDEEDE 426



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 23/78 (29%), Positives = 50/78 (64%), Gaps = 5/78 (6%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQ-KSDAEEDGGTVS 564
           +K+    + +  +  + ++K+EEE K++E+ + +EEEE ++K EE++ ++  EE+G +  
Sbjct: 363 RKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKD 422

Query: 565 QEEED----RKPKAEEDE 578
           +E+ED    +KP+ E  +
Sbjct: 423 EEDEDEDGGQKPEGEPQQ 440



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 2/81 (2%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD--AEEDGGTV 563
           +K+    E  K    + +++ + EE+ E KD+ DE+E+G +K E + + D   EE  G V
Sbjct: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451

Query: 564 SQEEEDRKPKAEEDEILNRSP 584
            +E  D     + DE++   P
Sbjct: 452 EEEPLDEAQDDDLDELMEMEP 472



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 5/65 (7%)

Query: 525 KEEEEEKEEEKDKGDE-----EEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
           ++E +EKEEE+ K +E     EE+ EE+ EE ++ + EE+    ++EE + K + +EDE 
Sbjct: 370 QQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDED 429

Query: 580 LNRSP 584
             + P
Sbjct: 430 GGQKP 434



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAE--EDGGTV 563
           ++++   EY   D  Q   +     K++ K     ++E +EK EE+ K + E  +     
Sbjct: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394

Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
            +EEE+ K K EE+EI N++    + + E
Sbjct: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDE 423


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 30/99 (30%), Positives = 53/99 (53%), Gaps = 13/99 (13%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEE-----------KDKGDEEEEGEEKLEEKQK 553
           GK++    E +K    +   KE E+ KE+E           K K +EE E EE+ EE++K
Sbjct: 27  GKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEK 86

Query: 554 SDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
            + E++ G   ++++ R+ K EE+E   +  R RK +++
Sbjct: 87  EEEEKEEGRRRKKKKKRRRKEEEEE--KKKKRRRKTKKK 123



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 25/87 (28%), Positives = 50/87 (57%), Gaps = 1/87 (1%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           +++  G   +K    + + +++++ KE EK K  EEEE + K + K+K + EE+     +
Sbjct: 22  EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE-EEEREEEEE 80

Query: 566 EEEDRKPKAEEDEILNRSPRNRKPRRE 592
           EEE+ K + E++E   R  + ++ R+E
Sbjct: 81  EEEEEKEEEEKEEGRRRKKKKKRRRKE 107



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 25/69 (36%), Positives = 41/69 (59%), Gaps = 1/69 (1%)

Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD-AEEDGGTVSQEEEDRKPKAEEDEILNRS 583
           K++E E+ EE ++ +EEEE E K +EK+K    E++    ++E E RK K EE++   R 
Sbjct: 6   KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65

Query: 584 PRNRKPRRE 592
            + +K   E
Sbjct: 66  RKKKKEEEE 74



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 5/69 (7%)

Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEED----- 569
           KK +  + +  EE EE+EE++ K  E+ + + K +EK+K   E +     +EEE      
Sbjct: 6   KKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK 65

Query: 570 RKPKAEEDE 578
           RK K EE+E
Sbjct: 66  RKKKKEEEE 74


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 24/69 (34%), Positives = 44/69 (63%), Gaps = 6/69 (8%)

Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDA------EEDGGTVSQEEE 568
           ++ +  + + +EEEEE+EEE+D  +EEE+ EE  EE+++ +       EE+ G + +EEE
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947

Query: 569 DRKPKAEED 577
           +   + EE+
Sbjct: 948 EEDEEEEEE 956



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 25/53 (47%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           EEEEE+EEE+++ +EEEE EE  EE+++ D EE      +EEE+ + + EE+E
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEE-DEEEYFEEEEEEEEEFEEEFEEEE 939



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 21/58 (36%), Positives = 39/58 (67%)

Query: 521 QPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           + + +EEEEE+EEE+++ +E+ E EE+ EE+   + EE+     +E E+ + + EE+E
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 23/66 (34%), Positives = 42/66 (63%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
           E ++ +  + + +EEE+ +EEE+D+ +  EE EE+ EE ++   EE+G    +EEE+ + 
Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEE 952

Query: 573 KAEEDE 578
           + EE E
Sbjct: 953 EEEELE 958



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 22/67 (32%), Positives = 43/67 (64%), Gaps = 5/67 (7%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
           E ++ +  + D +EEEE++EE  ++ +EEEE  E+  E+++ + EE+     +EEED + 
Sbjct: 899 EEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE-----EEEEDEEE 953

Query: 573 KAEEDEI 579
           + E +E+
Sbjct: 954 EEELEEV 960



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 18/51 (35%), Positives = 29/51 (56%)

Query: 528 EEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           EE+         +EEE EE+ EE+++ + EE+     +EEED +   EE+E
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE 925



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 21/59 (35%), Positives = 39/59 (66%), Gaps = 3/59 (5%)

Query: 513 EYKKTDAPQPDVKEEE--EEKEEEKDKGDEE-EEGEEKLEEKQKSDAEEDGGTVSQEEE 568
           E ++ D  + +  EEE  EE+EEE+++ +EE EE E +LEE+++ + EE+   + + E+
Sbjct: 904 EEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 21/60 (35%), Positives = 34/60 (56%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
           EY + +  + +  EEE E+EE + + +EEEE EE+ EE ++ +  E G    + EE   P
Sbjct: 919 EYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPP 978



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 17/78 (21%), Positives = 43/78 (55%), Gaps = 2/78 (2%)

Query: 270 VNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPE 329
           +N S E E+ E+ + E+ +E  +  + E  + ++ DE+   +  +EE  + E   ++E  
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEE--EEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG 940

Query: 330 YVPDPDAEKPEDWDEDMD 347
            + + + E+ E+ +E+++
Sbjct: 941 ELEEEEEEEDEEEEEELE 958


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 27/78 (34%), Positives = 47/78 (60%), Gaps = 5/78 (6%)

Query: 503 CSGKKQTSGMEYKKTDAPQPDVKEEEE--EKEEEKDKGDEEEEGEEKLEEKQKSDAEEDG 560
           C     T  M+ K+ D  +   ++ +E  +++EE ++GD EEE  E++EE+ + D +EDG
Sbjct: 90  CDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEE--EEIEEEDEDD-DEDG 146

Query: 561 GTVSQEEEDRKPKAEEDE 578
             V  EEE+ + + EE+E
Sbjct: 147 EDVEDEEEEEEEEEEEEE 164



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 502 CCSGKKQTSGMEYKKTDAPQ--PDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED 559
           C   KK+ +  +  +  AP+  P   + +    +E D  D  E+ +EK E++ +  +E++
Sbjct: 55  CPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDN 114

Query: 560 GGTVSQEEEDRKPKAEEDE 578
                ++EED +   EE+E
Sbjct: 115 DEPGDEDEEDEEGDREEEE 133



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 20/65 (30%), Positives = 36/65 (55%), Gaps = 4/65 (6%)

Query: 516 KTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQK--SDAEEDGGTVSQEEEDRKPK 573
           K D+   D  ++ +  E+  +K  EE+EGEE  E+  +   + EED     +EEE+ + +
Sbjct: 81  KADSSSVDECDDSDGTEDMDEK--EEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE 138

Query: 574 AEEDE 578
            E+D+
Sbjct: 139 DEDDD 143


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 39/59 (66%)

Query: 521 QPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
           Q  +  EEEE EEE+++ +EEE+ EEK E++++ + EE+     +EEE    K EE+++
Sbjct: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 30/95 (31%), Positives = 54/95 (56%), Gaps = 9/95 (9%)

Query: 489 LTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKL 548
           L+VA    LV   C + +    G+  ++ +  + + + EEEEKEEEK++ +EEEE EE+ 
Sbjct: 97  LSVARTAALVAEECSAQQ----GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEK 152

Query: 549 EEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRS 583
           EE ++ + +E      ++ E+ K + E D  + R+
Sbjct: 153 EEDEEEEEKE-----GKKMEEEKVEEEIDTEIQRT 182



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 19/69 (27%), Positives = 37/69 (53%)

Query: 524 VKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRS 583
           V EE   ++    + +E EE EE++EE++K + +E+     ++EE+++   EE+E   + 
Sbjct: 106 VAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKK 165

Query: 584 PRNRKPRRE 592
               K   E
Sbjct: 166 MEEEKVEEE 174



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 16/56 (28%), Positives = 36/56 (64%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEE 568
           E  + +  + + +E+EEE+E+E++K ++EEE E++ ++ ++   EE+  T  Q  +
Sbjct: 128 EEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 24/61 (39%), Positives = 41/61 (67%), Gaps = 5/61 (8%)

Query: 520 PQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
           PQ + KEEEEE+EE++++ +E+EE EE+ EE+++ + EE+     +EEE+        E+
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEE-----EEEEEAAAAVALGEV 781

Query: 580 L 580
           L
Sbjct: 782 L 782



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 22/54 (40%), Positives = 37/54 (68%), Gaps = 5/54 (9%)

Query: 521 QPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKA 574
           QP    +EEE+EEE+D+ +EEE+ EE+ EE+++ + EE+     +EEE+ +  A
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEE-----EEEEEEEAAA 774



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 18/44 (40%), Positives = 34/44 (77%)

Query: 516 KTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED 559
           + +  + + +EEE+E+EEE+D+ +EEEE EE+ EE+++ + EE+
Sbjct: 728 QANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 20/49 (40%), Positives = 37/49 (75%), Gaps = 2/49 (4%)

Query: 508 QTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDA 556
           Q +G E ++ +  + D +EEEE++EEE+++ +EEEE EE+ EE++++ A
Sbjct: 728 QANGKEEEEEE--EEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAA 774



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 19/55 (34%), Positives = 33/55 (60%)

Query: 520 PQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKA 574
           P   V+ +   KEEE+++ ++EEE EE  EE+++ + EE+     +EEE+    A
Sbjct: 721 PLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAA 775



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 17/40 (42%), Positives = 27/40 (67%)

Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEE 546
           K+    E +  +  + D +EEEEE+EEE+++ +EEEE EE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 16/42 (38%), Positives = 29/42 (69%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGE 545
           +GK++    E  + +  + + +EEEEE+EEE+++ +EEEE E
Sbjct: 730 NGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 24/103 (23%), Positives = 45/103 (43%), Gaps = 27/103 (26%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEE------------------EEGEEKLEEKQK- 553
           E ++ D  + + +EEEEE+EEE+++ +EE                   EG E+  ++ + 
Sbjct: 743 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQE 802

Query: 554 --------SDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
                    D +E  G  S  + D +P+     ++  SP + K
Sbjct: 803 GAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMK 845


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 4/87 (4%)

Query: 504  SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
            S  K  S  +Y  +   +P   E  +  E  K+  +EEEE E++ EE+++ + EED    
Sbjct: 1035 SPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEED---- 1090

Query: 564  SQEEEDRKPKAEEDEILNRSPRNRKPR 590
             +EEE+ + + EE+ I +  PR  KP+
Sbjct: 1091 EEEEEEEEEEEEEENIQSSPPRLTKPQ 1117



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 29/77 (37%), Positives = 45/77 (58%), Gaps = 5/77 (6%)

Query: 502  CCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGG 561
            C      TS  E  + D  +P+ +EEEEE+EEE+   +EEEEGEE  EE   +  ++  G
Sbjct: 1330 CAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEE---EEEEEGEE--EEGGGNVEKDPDG 1384

Query: 562  TVSQEEEDRKPKAEEDE 578
              SQE+E+ +   E+++
Sbjct: 1385 AKSQEKEEPEISTEKED 1401



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 10/73 (13%)

Query: 525  KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSP 584
            +EEEEE EEE+++ +EEEE EE+ EE+++ + EE+     Q    R  K +   I  + P
Sbjct: 1071 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEN----IQSSPPRLTKPQSVAIKRKRP 1126

Query: 585  ------RNRKPRR 591
                  R RK RR
Sbjct: 1127 FVLKKKRGRKRRR 1139



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 8/73 (10%)

Query: 513  EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGE----EKLEEKQKSDAEEDGGTV----S 564
            E ++ +  + + +EEEEE EEE+  G+ E++ +    ++ EE + S  +ED   +     
Sbjct: 1351 EEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEE 1410

Query: 565  QEEEDRKPKAEED 577
            +EEED +P   ED
Sbjct: 1411 EEEEDEEPSHNED 1423



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 2/68 (2%)

Query: 515  KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEE-KLEEKQKSDAEEDGGTVSQE-EEDRKP 572
            K  +  +P++  E+E+     D  +EEEE EE    E   +D E+D    S E E++  P
Sbjct: 1386 KSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELP 1445

Query: 573  KAEEDEIL 580
            +    E+L
Sbjct: 1446 RESFKEVL 1453



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 14/56 (25%), Positives = 31/56 (55%)

Query: 504  SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED 559
            S +K+   +  +K D+ + D  EEEEE++EE    ++ +  +E     + ++ E++
Sbjct: 1387 SQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKE 1442



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 32/137 (23%)

Query: 259  SGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDP-----------EAVKPDDWDE- 306
            +G  LN  TPP  P    E     + ++  E    P P           EA+ P + +  
Sbjct: 1267 TGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRR 1326

Query: 307  ----------DAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPED------WDEDMDG-- 348
                       +P + P+++  KPE   ++E E   + + E+ E+       ++D DG  
Sbjct: 1327 EETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAK 1386

Query: 349  --EWEAPQIANPRCESA 363
              E E P+I+  + +SA
Sbjct: 1387 SQEKEEPEISTEKEDSA 1403


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 22/59 (37%), Positives = 40/59 (67%), Gaps = 2/59 (3%)

Query: 521 QPDVKEEEEEKEEEKDKGDEE--EEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
           + + +EE E +EE +D+ DEE  E+ EE++E++Q+S+AEED     + E + + +AE +
Sbjct: 104 ESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESE 162



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 16/55 (29%), Positives = 35/55 (63%)

Query: 523 DVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
           +++ E  E+ E +++ + EEE E + E + +SD E +  +  + E++++ +AEED
Sbjct: 90  EIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEED 144



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 23/78 (29%), Positives = 44/78 (56%), Gaps = 3/78 (3%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEE-EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
           ++++   E  +T+    D  +EE EE  EE+ + ++E E EE  +E+ +S+AE  G T +
Sbjct: 102 EEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAE--GETEA 159

Query: 565 QEEEDRKPKAEEDEILNR 582
           + E D + + E + +  R
Sbjct: 160 ESEFDPEIEMEAERVAKR 177



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 18/52 (34%), Positives = 34/52 (65%), Gaps = 1/52 (1%)

Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
           +EE E + E+++  E E GEE  E +++S++EE+  T  + E++   ++EED
Sbjct: 78  KEEAEVKVEQEREIESEAGEES-ESEEESESEEESETEEESEDESDEESEED 128



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 21/52 (40%), Positives = 32/52 (61%), Gaps = 2/52 (3%)

Query: 528 EEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAE-EDE 578
           E+E+E E + G EE E EE+ E +++S+ EE+    S EE +   + E EDE
Sbjct: 86  EQEREIESEAG-EESESEEESESEEESETEEESEDESDEESEEDSEEEMEDE 136



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 17/64 (26%), Positives = 35/64 (54%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKP 572
           E +  +  + D +EE E+++E + + D +EEGE + E + ++++E D     + E   K 
Sbjct: 118 EDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKR 177

Query: 573 KAEE 576
           K  +
Sbjct: 178 KCPD 181



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 17/53 (32%), Positives = 24/53 (45%)

Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           E+E E E E  +  E EE  E  EE +  +  ED      EE+  +   +E E
Sbjct: 86  EQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQE 138



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 25/97 (25%), Positives = 47/97 (48%), Gaps = 8/97 (8%)

Query: 270 VNPSREIEDP--EDRKPEDWDERPKIPDPEAVKPDDWDE----DAPAKIPDEEATKPEGW 323
           V   REIE    E+ + E+  E  +  + E    D+ DE    D+  ++ DE+ ++ E  
Sbjct: 85  VEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEED 144

Query: 324 LDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRC 360
             +E E   + + E   ++D ++  E EA ++A  +C
Sbjct: 145 NQEEGESEAEGETEAESEFDPEI--EMEAERVAKRKC 179


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 6/60 (10%)

Query: 519 APQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           A  P+VKEEE EKEEE+ + +EEEE     +E  KSD  E+GG+  +E    K + E++E
Sbjct: 515 ATAPEVKEEEGEKEEEEGQEEEEEE-----DEGAKSDQAEEGGS-EKEGSSEKEEGEQEE 568



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 21/68 (30%), Positives = 40/68 (58%), Gaps = 2/68 (2%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKD-KGDEEEE-GEEKLEEKQKSDAEEDGGTVSQEEEDR 570
           E K+ +  + + + +EEE+EE++  K D+ EE G EK    +K + E++ G    E E  
Sbjct: 519 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE 578

Query: 571 KPKAEEDE 578
           + +A+E++
Sbjct: 579 EAEAKEEK 586



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 10/77 (12%)

Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGD---------EEEEGEEKLEEKQKSDAEED-GG 561
           M+ +K +A +   +E E E+EE   K           +EEEGE++ EE Q+ + EED G 
Sbjct: 484 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 543

Query: 562 TVSQEEEDRKPKAEEDE 578
              Q EE    K    E
Sbjct: 544 KSDQAEEGGSEKEGSSE 560



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 4/66 (6%)

Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD----AEEDGGTVSQEEEDR 570
           +K  +P P    EE + + E  KG+++EE E++++E  K +     EE    V ++++  
Sbjct: 676 EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAE 735

Query: 571 KPKAEE 576
            P  EE
Sbjct: 736 SPVKEE 741



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 8/82 (9%)

Query: 509 TSGMEYKKTDAPQPDVKEE-EEEKEEEKDKGDEEEEGEEKL----EEKQKSDAEEDGGTV 563
           +S ++  K +AP+  V+ +  EE  EE    DE+ E EE L    EE   S  EE     
Sbjct: 433 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 492

Query: 564 SQEEEDRKPKAEEDEI-LNRSP 584
            ++EE+  P+AEE+E+   +SP
Sbjct: 493 EEKEEE--PEAEEEEVAAKKSP 512



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)

Query: 527 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRN 586
           E+EE E+E+ + + E EGEE   +++K   E+     ++EE     K E+ E   +SP  
Sbjct: 560 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE-KAKSPVP 618

Query: 587 RKPRRE 592
           + P  E
Sbjct: 619 KSPVEE 624



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 16/49 (32%), Positives = 29/49 (59%), Gaps = 1/49 (2%)

Query: 526 EEEEEKEEEKDKGDEEEEGEEK-LEEKQKSDAEEDGGTVSQEEEDRKPK 573
           ++E+EKE+   +G  EEEG +K  +  +K D   +G    +EE +++ K
Sbjct: 769 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 817



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED---- 559
           S + +  G E K+  + + + ++EE E E E +  + E + E+K+EEK +  A ++    
Sbjct: 545 SDQAEEGGSE-KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 603

Query: 560 GGTVSQEEEDRKPKAEED-EILNRSPRNRKPRRE 592
              V + E+ + P  +   E   +SP  + P  E
Sbjct: 604 DAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEE 637


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 6/60 (10%)

Query: 519 APQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           A  P+VKEEE EKEEE+ + +EEEE     +E  KSD  E+GG+  +E    K + E++E
Sbjct: 139 ATAPEVKEEEGEKEEEEGQEEEEEE-----DEGAKSDQAEEGGS-EKEGSSEKEEGEQEE 192



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 21/68 (30%), Positives = 40/68 (58%), Gaps = 2/68 (2%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKD-KGDEEEE-GEEKLEEKQKSDAEEDGGTVSQEEEDR 570
           E K+ +  + + + +EEE+EE++  K D+ EE G EK    +K + E++ G    E E  
Sbjct: 143 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGE 202

Query: 571 KPKAEEDE 578
           + +A+E++
Sbjct: 203 EAEAKEEK 210



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 10/77 (12%)

Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGD---------EEEEGEEKLEEKQKSDAEED-GG 561
           M+ +K +A +   +E E E+EE   K           +EEEGE++ EE Q+ + EED G 
Sbjct: 108 MKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 167

Query: 562 TVSQEEEDRKPKAEEDE 578
              Q EE    K    E
Sbjct: 168 KSDQAEEGGSEKEGSSE 184



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 4/66 (6%)

Query: 515 KKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD----AEEDGGTVSQEEEDR 570
           +K  +P P    EE + + E  KG+++EE E++++E  K +     EE    V ++++  
Sbjct: 300 EKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAE 359

Query: 571 KPKAEE 576
            P  EE
Sbjct: 360 SPVKEE 365



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 8/82 (9%)

Query: 509 TSGMEYKKTDAPQPDVKEE-EEEKEEEKDKGDEEEEGEEKL----EEKQKSDAEEDGGTV 563
           +S ++  K +AP+  V+ +  EE  EE    DE+ E EE L    EE   S  EE     
Sbjct: 57  SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 116

Query: 564 SQEEEDRKPKAEEDEI-LNRSP 584
            ++EE+  P+AEE+E+   +SP
Sbjct: 117 EEKEEE--PEAEEEEVAAKKSP 136



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)

Query: 527 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRN 586
           E+EE E+E+ + + E EGEE   +++K   E+     ++EE     K E+ E   +SP  
Sbjct: 184 EKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE-KAKSPVP 242

Query: 587 RKPRRE 592
           + P  E
Sbjct: 243 KSPVEE 248



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 16/49 (32%), Positives = 29/49 (59%), Gaps = 1/49 (2%)

Query: 526 EEEEEKEEEKDKGDEEEEGEEK-LEEKQKSDAEEDGGTVSQEEEDRKPK 573
           ++E+EKE+   +G  EEEG +K  +  +K D   +G    +EE +++ K
Sbjct: 393 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 441



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 6/94 (6%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEED---- 559
           S + +  G E K+  + + + ++EE E E E +  + E + E+K+EEK +  A ++    
Sbjct: 169 SDQAEEGGSE-KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227

Query: 560 GGTVSQEEEDRKPKAEED-EILNRSPRNRKPRRE 592
              V + E+ + P  +   E   +SP  + P  E
Sbjct: 228 DAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEE 261


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 5/74 (6%)

Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           ++T  +E  K      +  EEEEE+EEE+++ +E EE EE+  E + S+ +E+   VS E
Sbjct: 513 EETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDE 572

Query: 567 EE-----DRKPKAE 575
           ++     D+KP  E
Sbjct: 573 KDSGKTLDKKPSKE 586



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 4/62 (6%)

Query: 523 DVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNR 582
           +VKE  EE+EEE    +EEEE +E+ EE+++ + E +G    +E+E    + +  + L++
Sbjct: 526 EVKENPEEEEEE----EEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDK 581

Query: 583 SP 584
            P
Sbjct: 582 KP 583



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 24/83 (28%), Positives = 48/83 (57%), Gaps = 7/83 (8%)

Query: 510 SGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEED 569
           S  E +K +  +  ++ +E  +EEE+++ +EEE+ E + EE+++ ++E   G    +EED
Sbjct: 511 SDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEG----DEED 566

Query: 570 RKPKAEEDEILNRSPRNRKPRRE 592
            K   E+D   +    ++KP +E
Sbjct: 567 EKVSDEKD---SGKTLDKKPSKE 586



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 1/88 (1%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEE-EKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
           KK  S    K        +KEEEE +K EE+++    EE E K +E+++ + E+      
Sbjct: 333 KKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQ 392

Query: 565 QEEEDRKPKAEEDEILNRSPRNRKPRRE 592
           +E+E ++   +E ++L +S R  + R E
Sbjct: 393 KEKERKERLKKEGKLLTKSQREARARAE 420



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 20/85 (23%), Positives = 42/85 (49%)

Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           K+    E ++ +  + D + EEEE+EE + +G E +E +EK+ +++ S    D     + 
Sbjct: 528 KENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEM 587

Query: 567 EEDRKPKAEEDEILNRSPRNRKPRR 591
             D +  +++D        ++  RR
Sbjct: 588 SSDSEYDSDDDRTKEERAYDKAKRR 612



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 21/76 (27%), Positives = 44/76 (57%), Gaps = 2/76 (2%)

Query: 519 APQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSD--AEEDGGTVSQEEEDRKPKAEE 576
           A + D + ++++K+++K KG++EE+ +EK +   K+   A ++     +EEE+R+ + EE
Sbjct: 304 AAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE 363

Query: 577 DEILNRSPRNRKPRRE 592
           + I        K + E
Sbjct: 364 ERIKRLEELEAKRKEE 379



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 28/75 (37%), Positives = 41/75 (54%), Gaps = 9/75 (12%)

Query: 525 KEEEEEKEEEKDKGDEE------EEGEEKL-EEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
           K E+EEKE+EK KG  +      +E   KL EE+++   EE+      EE + K K  E+
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRK--EE 379

Query: 578 EILNRSPRNRKPRRE 592
           E L +  R RK ++E
Sbjct: 380 ERLEQEKRERKKQKE 394



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 33/139 (23%), Positives = 56/139 (40%), Gaps = 21/139 (15%)

Query: 210 KTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPP 269
           K  IYE+K  K+    L++    +             S E+     V+  G    + TPP
Sbjct: 442 KRPIYEDKKRKKIPQQLESKEVSE-------------SMELCAAVEVMEQGVPEKEETPP 488

Query: 270 VNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPE 329
                E ED ED   +DW+      + E V+ +        K+  E    PE   ++E E
Sbjct: 489 PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGN--------KVHIEVKENPEEEEEEEEE 540

Query: 330 YVPDPDAEKPEDWDEDMDG 348
              D ++E+ E+ + + +G
Sbjct: 541 EEEDEESEEEEEEEGESEG 559



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 6/91 (6%)

Query: 506 KKQTSGMEYKKTD---APQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGT 562
           K +    E KK D   A    +KE+EE +  +KD+  ++E   +  EE  KS    D G 
Sbjct: 232 KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGV 291

Query: 563 V-SQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
           + + EE+   P A ED+  N   + +K +++
Sbjct: 292 IPASEEKAETPTAAEDD--NEGDKKKKDKKK 320



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)

Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNR 582
           +++ E+KE E+ K DEE+    KL+EK++    E G     ++++ + K EE+ + ++
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEEL---ETGKKDQSKQKESQRKFEEETVKSK 284



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 17/94 (18%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKD---------KGDEEEEGEEKLEEK--- 551
           S  K+  G + KK      D +E E++  + K           G ++++   KL +K   
Sbjct: 93  SKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKG 152

Query: 552 --QKSDAEEDGGTVSQEEEDRKPKAEEDEILNRS 583
             QKS+ + DG   S+E+ED   K +E   +N S
Sbjct: 153 KAQKSNKKWDG---SEEDEDNSKKIKERSRINSS 183



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 6/83 (7%)

Query: 516 KTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAE 575
           K D     VK  E  +EE   K  +++  + K +    +D+EE     S+ ++  KPK E
Sbjct: 73  KADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVE 132

Query: 576 ------EDEILNRSPRNRKPRRE 592
                 +D+  N+ P+  K + +
Sbjct: 133 MYSGSDDDDDFNKLPKKAKGKAQ 155



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 25/118 (21%), Positives = 46/118 (38%), Gaps = 29/118 (24%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEE----------EEEKEEEKDKGDEEEEGEEKLEEKQK 553
           +GKK  S  +  +    +  VK +           EEK E     +++ EG++K ++K+K
Sbjct: 261 TGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKK 320

Query: 554 SDAEED-------------------GGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
              E++                         +EE+ + K EE+E + R       R+E
Sbjct: 321 KKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKE 378



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 12/97 (12%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEK-----DKGDEEEEGEEKLEEKQKSDAEED 559
           GK Q S    KK D  + D    ++ KE  +     + GDE +E  +  + ++K+   + 
Sbjct: 152 GKAQKSN---KKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKP 208

Query: 560 GGTVSQEEEDR----KPKAEEDEILNRSPRNRKPRRE 592
           G  +    ED     K K    +   +  R RK R E
Sbjct: 209 GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDE 245


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 21/67 (31%), Positives = 45/67 (67%), Gaps = 4/67 (5%)

Query: 526 EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPR 585
           EEEEE+EEE+++ DEEEEG+++ ++ +++   ++     +EE +  P+ + +E+++  P+
Sbjct: 270 EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKE----FKEEGEEIPRVKPEEMMDERPK 325

Query: 586 NRKPRRE 592
            R   +E
Sbjct: 326 TRSQEQE 332



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 23/79 (29%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 516 KTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPK-- 573
           KT+  + + +EEEE+ EEE+   + ++  E  + ++ K + EE      +E  D +PK  
Sbjct: 268 KTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTR 327

Query: 574 AEEDEILNRSPRNRKPRRE 592
           ++E E+L R  R  + + E
Sbjct: 328 SQEQEVLERGGRFTRSQEE 346



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 18/68 (26%), Positives = 34/68 (50%)

Query: 525  KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSP 584
            KE+EEE+++E++K  E E   +   EK++  + E      +E E  +   + D   +R  
Sbjct: 1253 KEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRER 1312

Query: 585  RNRKPRRE 592
               + RR+
Sbjct: 1313 GRERDRRD 1320



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 16/68 (23%), Positives = 34/68 (50%)

Query: 525  KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSP 584
            + +E EK  ++ + +E++E E++ E ++    E +       E DR+ + E +       
Sbjct: 1244 RAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRD 1303

Query: 585  RNRKPRRE 592
            R+R+  RE
Sbjct: 1304 RDRERDRE 1311



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 18/69 (26%), Positives = 35/69 (50%), Gaps = 7/69 (10%)

Query: 524  VKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRS 583
            V++E E  E  K++    +E EE+ +++++ +AE +     + E+ R+   E D      
Sbjct: 1235 VQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERD------ 1288

Query: 584  PRNRKPRRE 592
             R R+  RE
Sbjct: 1289 -RERERERE 1296



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 14/67 (20%), Positives = 35/67 (52%)

Query: 526  EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPR 585
            E  +E+E+ + + +EEE+ E + E +++ + + +     +   +R  + E +   +R  R
Sbjct: 1243 ERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDR 1302

Query: 586  NRKPRRE 592
            +R   R+
Sbjct: 1303 DRDRERD 1309


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 24/56 (42%), Positives = 41/56 (73%), Gaps = 1/56 (1%)

Query: 525  KEEEEEKEEEKDKGDEE-EEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
            KEEEE+K+++K+K  EE +E EE  EEK++  +EE+  ++S EEE+ +  + E+E+
Sbjct: 2282 KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV 2337



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 23/56 (41%), Positives = 37/56 (66%), Gaps = 2/56 (3%)

Query: 521  QPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEE 576
            Q  +  EEEE+ EE+++ +EEE  EE+ E K++ + EE    V +EEE++K K +E
Sbjct: 2240 QESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK--QVEKEEEEKKKKKKE 2293



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 26/78 (33%), Positives = 48/78 (61%), Gaps = 3/78 (3%)

Query: 506  KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
            +KQ S    ++ +  + + +EEEE +EEE+++  EEEEGEEK  EK++ + ++      +
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEER-KEEEEGEEKQVEKEEEEKKKKKKEKKK 2296

Query: 566  EEEDRKPKA--EEDEILN 581
            EE   K +   E++EI++
Sbjct: 2297 EEVQEKEEVFEEKEEIMS 2314



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 19/67 (28%), Positives = 43/67 (64%)

Query: 512  MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
            +E +++ + + + + EEEE+ EE++  +EEEE +E+ E ++K   +E+     +++E +K
Sbjct: 2237 LEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKK 2296

Query: 572  PKAEEDE 578
             + +E E
Sbjct: 2297 EEVQEKE 2303



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 11/98 (11%)

Query: 506  KKQTSGMEYKKTDAPQPDVKEEEE-----------EKEEEKDKGDEEEEGEEKLEEKQKS 554
            K+   G + K+  + Q D  E EE           E E+++    EEEE  E+ EE+++ 
Sbjct: 2201 KEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE 2260

Query: 555  DAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE 592
            +  E+     +EEE  + + E++E   +  +  K + E
Sbjct: 2261 EVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 7/69 (10%)

Query: 521  QPDVKEEEEEKEEEKDKGDEEEEG----EEKLEEKQKSDAEEDGGTVSQEE---EDRKPK 573
            + ++ +EE +  EEK K  EEEE      EKL E++   A+E+   + ++E   + ++  
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791

Query: 574  AEEDEILNR 582
             EE+E L R
Sbjct: 1792 PEEEERLGR 1800



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 19/87 (21%), Positives = 43/87 (49%)

Query: 505  GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
            G+++    E ++    + + K+EE +++EE  +  EE   EE+ E     + EE+  ++ 
Sbjct: 2275 GEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE 2334

Query: 565  QEEEDRKPKAEEDEILNRSPRNRKPRR 591
            +E +  K   ++++      + RK  R
Sbjct: 2335 EEVDREKEILKKEKQFKLQEQRRKSLR 2361


>gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]
          Length = 111

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 28/65 (43%), Positives = 37/65 (56%), Gaps = 4/65 (6%)

Query: 518 DAPQPDVKEEEEEKEEEKDK--GDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDR--KPK 573
           DAP     E EE  E+E D    +EEEEG E+ EE+++ D EE+ G   +E E    K  
Sbjct: 32  DAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRA 91

Query: 574 AEEDE 578
           AE+DE
Sbjct: 92  AEDDE 96



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 6/72 (8%)

Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           +Q +  E  + +    + +EEEEE + E++ GDE+EE E    ++   D E+D      +
Sbjct: 46  EQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATGKRAAEDDEDD------D 99

Query: 567 EEDRKPKAEEDE 578
            + +K K +ED+
Sbjct: 100 VDTKKQKTDEDD 111



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 7/63 (11%)

Query: 523 DVKEEEEEKEEEKDKGD-------EEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAE 575
           D+KE++E  EE ++  D       E EE  E+  + +  + EE+GG   +EEE+   + E
Sbjct: 16  DLKEKKEVVEEAENGRDAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEE 75

Query: 576 EDE 578
           + +
Sbjct: 76  DGD 78


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           +++TS  E    ++     +EEEEE+EEE+++G   EE EE+ EE+++ + EE G    +
Sbjct: 261 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 318

Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
             E    +  E+E+     R  +
Sbjct: 319 ASEQSAEEVSEEEMSEDEERENE 341



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
           S  +  S  E K + A     +     +EEE+++ +EEEEG   E+ EE+++ + EE+  
Sbjct: 252 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 311

Query: 562 TVSQEEEDRKPKAEE 576
           T S  EE  +  AEE
Sbjct: 312 TGSNSEEASEQSAEE 326



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
           SG       E ++ +  +    EE EE+EEE++  +EEEE     EE  +  AEE    V
Sbjct: 274 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 327

Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
           S+EE     + E +  L   P +R  R
Sbjct: 328 SEEEMSEDEERENENHLLVVPESRFDR 354



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
           ME +   +   D+ + E +    +    E   G E+ EE+++ + EE+G T  + EE+ +
Sbjct: 245 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 303

Query: 572 PKAEEDE 578
            + EE+E
Sbjct: 304 EEEEEEE 310



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
           E    E   G EEEE EE+ EE++ S +EE     S+EEE+ + + EE+   N    + +
Sbjct: 268 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 322

Query: 589 PRRE 592
              E
Sbjct: 323 SAEE 326



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)

Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           K  +EEK EE+D                  +    E G    EE+++ + EE+ G+ S+E
Sbjct: 238 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 297

Query: 567 EEDRKPKAEEDE 578
            E+ + + EE+E
Sbjct: 298 SEEEEEEEEEEE 309



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
           E ++    +   +EEEEE+EEE++ G   EE          EE++ E ++ + E     V
Sbjct: 288 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 347

Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
            +   DR   + +  E+E+   +P++
Sbjct: 348 PESRFDRDSGESEEAEEEVGEGTPQS 373



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 513 EYKKTDAPQPDVKEEEEEKE----EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEE 567
           E +K       VKE E E+     EE+DK   E E +++ E  ++ S  E D     + +
Sbjct: 103 EKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERK 162

Query: 568 EDRKPKAEEDEILNRSPRNRKPRRE 592
            +R+ K  E +   R  + R+ R E
Sbjct: 163 RERERKMREQQKEQREQKERERRAE 187


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           +++TS  E    ++     +EEEEE+EEE+++G   EE EE+ EE+++ + EE G    +
Sbjct: 271 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 328

Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
             E    +  E+E+     R  +
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENE 351



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
           S  +  S  E K + A     +     +EEE+++ +EEEEG   E+ EE+++ + EE+  
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321

Query: 562 TVSQEEEDRKPKAEE 576
           T S  EE  +  AEE
Sbjct: 322 TGSNSEEASEQSAEE 336



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
           SG       E ++ +  +    EE EE+EEE++  +EEEE     EE  +  AEE    V
Sbjct: 284 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 337

Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
           S+EE     + E +  L   P +R  R
Sbjct: 338 SEEEMSEDEERENENHLLVVPESRFDR 364



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
           ME +   +   D+ + E +    +    E   G E+ EE+++ + EE+G T  + EE+ +
Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 313

Query: 572 PKAEEDE 578
            + EE+E
Sbjct: 314 EEEEEEE 320



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
           E    E   G EEEE EE+ EE++ S +EE     S+EEE+ + + EE+   N    + +
Sbjct: 278 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 332

Query: 589 PRRE 592
              E
Sbjct: 333 SAEE 336



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)

Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           K  +EEK EE+D                  +    E G    EE+++ + EE+ G+ S+E
Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307

Query: 567 EEDRKPKAEEDE 578
            E+ + + EE+E
Sbjct: 308 SEEEEEEEEEEE 319



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
           E ++    +   +EEEEE+EEE++ G   EE          EE++ E ++ + E     V
Sbjct: 298 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 357

Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
            +   DR   + +  E+E+   +P++
Sbjct: 358 PESRFDRDSGESEEAEEEVGEGTPQS 383



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 5/74 (6%)

Query: 524 VKEEEEEKE----EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           VKE E E+     EE+DK   E E +++ E  ++ S  E D     + + +R+ K  E +
Sbjct: 124 VKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ 183

Query: 579 ILNRSPRNRKPRRE 592
              R  + R+ R E
Sbjct: 184 KEQREQKERERRAE 197


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 27/70 (38%), Positives = 41/70 (58%), Gaps = 2/70 (2%)

Query: 525  KEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDG--GTVSQEEEDRKPKAEEDEILNR 582
            +EE EE+ EE+ +G+EE EGE + EE+ + + E +G  G    EEE+ + + EE E    
Sbjct: 992  EEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGE 1051

Query: 583  SPRNRKPRRE 592
               NR+ R E
Sbjct: 1052 GEENRRNREE 1061



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 4/70 (5%)

Query: 513 EYKKTDAPQPDVKEEEE----EKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEE 568
           E+KK D  + + KE E+    E+ +E ++G EEE GE + EE  + + EE  G   +E E
Sbjct: 701 EWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGE 760

Query: 569 DRKPKAEEDE 578
             + + E ++
Sbjct: 761 GEEVEGEREK 770



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 25/73 (34%), Positives = 43/73 (58%), Gaps = 1/73 (1%)

Query: 505  GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGD-EEEEGEEKLEEKQKSDAEEDGGTV 563
            G+++  G E  + +  + +  E E E E E+ +G+ EEEEGEE+ EE++K    E+    
Sbjct: 999  GEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRN 1058

Query: 564  SQEEEDRKPKAEE 576
             +EEE+ + K +E
Sbjct: 1059 REEEEEEEGKYQE 1071



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 26/76 (34%), Positives = 44/76 (57%), Gaps = 10/76 (13%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGD--------EEEEGEEKLEEK--QKSDAEEDGGT 562
           E+ + +  + D +EEEE++ E K++G+        E+EEGE K EE+  ++   EE+G  
Sbjct: 734 EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQ 793

Query: 563 VSQEEEDRKPKAEEDE 578
              EEE+ + + EE E
Sbjct: 794 GEGEEEETEGRGEEKE 809



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 24/73 (32%), Positives = 42/73 (57%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           K++   +E  + +  + + +EEEEE E E+++G+ EEE  E  EE+ +   EE+G     
Sbjct: 808 KEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG 867

Query: 566 EEEDRKPKAEEDE 578
           EEE  + + E +E
Sbjct: 868 EEEGEEGEGEGEE 880



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 3/77 (3%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEE---EGEEKLEEKQKSDAEEDGG 561
           G +   G   ++ +  + + +EEE E EEE+ +G+EEE   +GEE+ EE +  +  E+G 
Sbjct: 816 GGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGE 875

Query: 562 TVSQEEEDRKPKAEEDE 578
              +EEE      EE E
Sbjct: 876 GEGEEEEGEGEGEEEGE 892



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 15/88 (17%)

Query: 506 KKQTSGMEYK-KTDAPQPDVKEEE-----EEKEE---------EKDKGDEEEEGEEKLEE 550
           K++ +G E K + +  Q + +EEE     EEKEE         E+ KG+ EEE EE   E
Sbjct: 777 KEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGE 836

Query: 551 KQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           +++ + EE+ G   +EE + K + E +E
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEE 864



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 24/67 (35%), Positives = 38/67 (56%)

Query: 511 GMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDR 570
           G E  +    + + +E E E EEE+ +G+ EEEGE + EE++     E+ G    EEE+ 
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917

Query: 571 KPKAEED 577
           + K EE+
Sbjct: 918 EGKGEEE 924



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/56 (44%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 526  EEEE---EKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
            EEEE   E EEE+ +G+ EEEGE + EE +    EE+G    +EEE  +   EE E
Sbjct: 949  EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 26/80 (32%), Positives = 46/80 (57%), Gaps = 6/80 (7%)

Query: 505 GKKQTSGMEYK-KTDAPQPDVKEEE-----EEKEEEKDKGDEEEEGEEKLEEKQKSDAEE 558
           GK++  G E + + +  + + K+EE     E+ EEE D+G+ EEE  E   E+++   E 
Sbjct: 755 GKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814

Query: 559 DGGTVSQEEEDRKPKAEEDE 578
           +GG V + + +R+ + EE E
Sbjct: 815 EGGEVEEGKGEREEEEEEGE 834



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 21/72 (29%), Positives = 40/72 (55%)

Query: 505  GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
            G+++  G    + +  + + + EEEE EEE ++ ++E EGEE    +++ + EE     +
Sbjct: 1013 GEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072

Query: 565  QEEEDRKPKAEE 576
             EEE+ +   EE
Sbjct: 1073 GEEENERQDGEE 1084



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 23/74 (31%), Positives = 39/74 (52%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVS 564
           G+++    E KK +    + K EEE  + E ++ + E  GEEK E  +    E + G   
Sbjct: 766 GEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGE 825

Query: 565 QEEEDRKPKAEEDE 578
           +EEE+ + + EE+E
Sbjct: 826 REEEEEEGEGEEEE 839



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 24/72 (33%), Positives = 39/72 (54%)

Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           ++  G E  +    + + +E E E EEE +   EEEEGE + EE+ + + EE+ G    E
Sbjct: 863 EEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE 922

Query: 567 EEDRKPKAEEDE 578
           EE  + + E +E
Sbjct: 923 EEGEEGEGEGEE 934



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 3/72 (4%)

Query: 507 KQTSGMEYKKTDAPQPDVKEEEEEKEE--EKDKGD-EEEEGEEKLEEKQKSDAEEDGGTV 563
           K+  G E ++ +  Q   KE  +E EE  E++ G+ EEEEG+ + EE+++ + +E+G   
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE 762

Query: 564 SQEEEDRKPKAE 575
             E E  K + E
Sbjct: 763 EVEGEREKEEGE 774



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 27/71 (38%), Positives = 41/71 (57%), Gaps = 10/71 (14%)

Query: 526  EEEEEKEEE-KDKGDEEEEGEEKLE---EKQKSDAEEDGGTVSQEEEDRKPKAEEDEILN 581
            EEE E EEE + +G+EEEEGE + E   E+ + + EE+ G    EE +++ + EE+    
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENR--- 1056

Query: 582  RSPRNRKPRRE 592
               RNR+   E
Sbjct: 1057 ---RNREEEEE 1064



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 26/76 (34%), Positives = 45/76 (59%), Gaps = 7/76 (9%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEK---EEEKDKGD-EEEEGEEKLEEKQKSDAEEDGG 561
           +++T G   +K +  + +  E EE K   EEE+++G+ EEEEGE    E+++ + EE+ G
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE---GEEEEGEGEEEEG 854

Query: 562 TVSQEEEDRKPKAEED 577
               EEE  + + EE+
Sbjct: 855 EGKGEEEGEEGEGEEE 870



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 1/73 (1%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGD-EEEEGEEKLEEKQKSDAEEDGGTVS 564
           +++  G E +     + + +E E E+E E+ +G+ EEEEGE + EE+ + + EE+ G   
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903

Query: 565 QEEEDRKPKAEED 577
            EEE      EE+
Sbjct: 904 GEEEGEGEGEEEE 916



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 20/53 (37%), Positives = 32/53 (60%)

Query: 526  EEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
            E EEE E E ++G+ E E EE   E ++ + EE+G    + EE+ + + EE+E
Sbjct: 965  EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 22/57 (38%), Positives = 35/57 (61%), Gaps = 3/57 (5%)

Query: 525 KEEEEEKEEEKDKGDEEEEGEEKLEEKQ---KSDAEEDGGTVSQEEEDRKPKAEEDE 578
           +E E E EEE+ +G+ EEEGE + EE++   K + E + G    EEE+ + + E+ E
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGE 945



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 1/55 (1%)

Query: 526  EEEEEKEEEKDKGD-EEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEI 579
            EEE E E E+ +G+ EEEEGE + EE++  +  E+ G   +E E    + EE E+
Sbjct: 967  EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV 1021



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 23/53 (43%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query: 526 EEEEEKEEEKDKGDEE-EEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEED 577
           E E E+EE + KG+EE EEGE + EE++     EDG    +EEE      EE+
Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 21/52 (40%), Positives = 31/52 (59%)

Query: 527 EEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           E E +EEE +   EEEEGE + EE+ + + EE  G   +EE + + + EE E
Sbjct: 945 EGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 8/81 (9%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGD-EEEEGE-EKLEEKQKSDAEEDG--- 560
           +++  G   ++ +  + + +EEE E E E  +G+ EEEEGE E  EE+ + + EE+G   
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973

Query: 561 ---GTVSQEEEDRKPKAEEDE 578
              G    EEE+ + + EE+E
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEE 994



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGD---EEEEGEEKLEEKQKSDAEEDGG 561
           G+++    E ++    + + +E E + EEE ++G+   EEEEGE + E+ +    EE+G 
Sbjct: 895 GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE 954

Query: 562 TVSQEEEDRKPKAEEDE 578
              +EEE      EE E
Sbjct: 955 WEGEEEEGEGEGEEEGE 971



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 1/75 (1%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGE-EKLEEKQKSDAEEDGGTV 563
           G+++    E ++ +  + + + + EE+ EE +  +E EEGE E  EE+ + + EE+G   
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894

Query: 564 SQEEEDRKPKAEEDE 578
            +EEE      EE E
Sbjct: 895 GEEEEGEGEGEEEGE 909



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 7/81 (8%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEK------EEEKDKGDEEE-EGEEKLEEKQKSDAE 557
           GK +  G E +  +  +    E EEE+      EE + +G+EEE EGE + E + + + E
Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915

Query: 558 EDGGTVSQEEEDRKPKAEEDE 578
           E  G   +E E+ + + EE+E
Sbjct: 916 EGEGKGEEEGEEGEGEGEEEE 936



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 2/66 (3%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           K++  G + ++    +   +EE  E EEE+   +EEEE E   E K++ + EE  G   +
Sbjct: 713 KEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEG--EGKEEGEGEEVEGEREK 770

Query: 566 EEEDRK 571
           EE +RK
Sbjct: 771 EEGERK 776



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 3/77 (3%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEK-EEEKDKGDEEEEGEEKLEEKQKSDAEEDG--G 561
           G+ +  G    + +  + + +EE E + EEE+ +G  EEEGEE   E ++ + E +G  G
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944

Query: 562 TVSQEEEDRKPKAEEDE 578
               EEE+ + + EE+E
Sbjct: 945 EGEGEEEEGEWEGEEEE 961



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 5/77 (6%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKS---DAEEDGG 561
           G+++    E ++    + + +E E E EEE +   EEEEGE K EE+ +    + EE+ G
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG 937

Query: 562 TVSQEEEDRKPKAEEDE 578
               E ED + + EE+E
Sbjct: 938 --EGEGEDGEGEGEEEE 952



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 24/83 (28%), Positives = 43/83 (51%), Gaps = 10/83 (12%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEK-------DKGDEE---EEGEEKLEEKQKSD 555
           +++  G   ++ +  + + + E+EE E +K       +KG+EE    EGEE+  E +  +
Sbjct: 748 EEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807

Query: 556 AEEDGGTVSQEEEDRKPKAEEDE 578
            EE G     E E+ K + EE+E
Sbjct: 808 KEEGGEVEGGEVEEGKGEREEEE 830



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 20/76 (26%), Positives = 41/76 (53%), Gaps = 3/76 (3%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEE--EKDKGDEEEEGEEK-LEEKQKSDAEEDGG 561
           G+K     E ++    + ++ E+EE K+   E+ +  E E+G +K   ++ +   EE+ G
Sbjct: 677 GEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG 736

Query: 562 TVSQEEEDRKPKAEED 577
              +EE DR+ + E++
Sbjct: 737 EGEEEEGDREEEEEKE 752



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 505 GKKQTSGMEYKKTDAPQPDVKEEEEEKEE-EKDKGDEEEEGEEKLE--EKQKSDAEEDGG 561
           G+ +  G   K+    +   K + EE+E+ E+++G ++E  +E  E  E++  + EE+ G
Sbjct: 684 GEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEG 743

Query: 562 TVSQEEEDRKPKAEEDE 578
              +EEE      EE E
Sbjct: 744 DREEEEEKEGEGKEEGE 760



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 5/70 (7%)

Query: 513  EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLE-----EKQKSDAEEDGGTVSQEE 567
            E ++ +    D + E EE+E E +  +EE EGE + E     E+ + + EE+ G    EE
Sbjct: 933  EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992

Query: 568  EDRKPKAEED 577
            E+ + + EE+
Sbjct: 993  EEGEEEGEEE 1002



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 18/55 (32%), Positives = 34/55 (61%), Gaps = 3/55 (5%)

Query: 526 EEEEEKEEEKDKGDEEE--EGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDE 578
           EE E+ E++K +G+ E   EGE++L EK++   + DG    Q+E ++  + E ++
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEW-KKRDGEEQEQKEREQGHQKERNQ 725


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           +++TS  E    ++     +EEEEE+EEE+++G   EE EE+ EE+++ + EE G    +
Sbjct: 262 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 319

Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
             E    +  E+E+     R  +
Sbjct: 320 ASEQSAEEVSEEEMSEDEERENE 342



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
           S  +  S  E K + A     +     +EEE+++ +EEEEG   E+ EE+++ + EE+  
Sbjct: 253 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 312

Query: 562 TVSQEEEDRKPKAEE 576
           T S  EE  +  AEE
Sbjct: 313 TGSNSEEASEQSAEE 327



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
           SG       E ++ +  +    EE EE+EEE++  +EEEE     EE  +  AEE    V
Sbjct: 275 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 328

Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
           S+EE     + E +  L   P +R  R
Sbjct: 329 SEEEMSEDEERENENHLLVVPESRFDR 355



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
           ME +   +   D+ + E +    +    E   G E+ EE+++ + EE+G T  + EE+ +
Sbjct: 246 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 304

Query: 572 PKAEEDE 578
            + EE+E
Sbjct: 305 EEEEEEE 311



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
           E    E   G EEEE EE+ EE++ S +EE     S+EEE+ + + EE+   N    + +
Sbjct: 269 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 323

Query: 589 PRRE 592
              E
Sbjct: 324 SAEE 327



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)

Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           K  +EEK EE+D                  +    E G    EE+++ + EE+ G+ S+E
Sbjct: 239 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 298

Query: 567 EEDRKPKAEEDE 578
            E+ + + EE+E
Sbjct: 299 SEEEEEEEEEEE 310



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
           E ++    +   +EEEEE+EEE++ G   EE          EE++ E ++ + E     V
Sbjct: 289 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 348

Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
            +   DR   + +  E+E+   +P++
Sbjct: 349 PESRFDRDSGESEEAEEEVGEGTPQS 374



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 7/85 (8%)

Query: 515 KKTDAPQPDVKEEEEEKE------EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEE 567
           K+ +     VKE+E E E      EE+DK   E E +++ E  ++ S  E D     + +
Sbjct: 104 KRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERK 163

Query: 568 EDRKPKAEEDEILNRSPRNRKPRRE 592
            +R+ K  E +   R  + R+ R E
Sbjct: 164 RERERKMREQQKEQREQKERERRAE 188


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           +++TS  E    ++     +EEEEE+EEE+++G   EE EE+ EE+++ + EE G    +
Sbjct: 271 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 328

Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
             E    +  E+E+     R  +
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENE 351



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
           S  +  S  E K + A     +     +EEE+++ +EEEEG   E+ EE+++ + EE+  
Sbjct: 262 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 321

Query: 562 TVSQEEEDRKPKAEE 576
           T S  EE  +  AEE
Sbjct: 322 TGSNSEEASEQSAEE 336



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
           SG       E ++ +  +    EE EE+EEE++  +EEEE     EE  +  AEE    V
Sbjct: 284 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 337

Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
           S+EE     + E +  L   P +R  R
Sbjct: 338 SEEEMSEDEERENENHLLVVPESRFDR 364



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
           ME +   +   D+ + E +    +    E   G E+ EE+++ + EE+G T  + EE+ +
Sbjct: 255 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 313

Query: 572 PKAEEDE 578
            + EE+E
Sbjct: 314 EEEEEEE 320



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
           E    E   G EEEE EE+ EE++ S +EE     S+EEE+ + + EE+   N    + +
Sbjct: 278 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 332

Query: 589 PRRE 592
              E
Sbjct: 333 SAEE 336



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)

Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           K  +EEK EE+D                  +    E G    EE+++ + EE+ G+ S+E
Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307

Query: 567 EEDRKPKAEEDE 578
            E+ + + EE+E
Sbjct: 308 SEEEEEEEEEEE 319



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
           E ++    +   +EEEEE+EEE++ G   EE          EE++ E ++ + E     V
Sbjct: 298 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 357

Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
            +   DR   + +  E+E+   +P++
Sbjct: 358 PESRFDRDSGESEEAEEEVGEGTPQS 383


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           +++TS  E    ++     +EEEEE+EEE+++G   EE EE+ EE+++ + EE G    +
Sbjct: 239 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 296

Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
             E    +  E+E+     R  +
Sbjct: 297 ASEQSAEEVSEEEMSEDEERENE 319



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
           S  +  S  E K + A     +     +EEE+++ +EEEEG   E+ EE+++ + EE+  
Sbjct: 230 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 289

Query: 562 TVSQEEEDRKPKAEE 576
           T S  EE  +  AEE
Sbjct: 290 TGSNSEEASEQSAEE 304



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
           SG       E ++ +  +    EE EE+EEE++  +EEEE     EE  +  AEE    V
Sbjct: 252 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 305

Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
           S+EE     + E +  L   P +R  R
Sbjct: 306 SEEEMSEDEERENENHLLVVPESRFDR 332



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
           ME +   +   D+ + E +    +    E   G E+ EE+++ + EE+G T  + EE+ +
Sbjct: 223 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 281

Query: 572 PKAEEDE 578
            + EE+E
Sbjct: 282 EEEEEEE 288



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
           E    E   G EEEE EE+ EE++ S +EE     S+EEE+ + + EE+   N    + +
Sbjct: 246 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 300

Query: 589 PRRE 592
              E
Sbjct: 301 SAEE 304



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)

Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           K  +EEK EE+D                  +    E G    EE+++ + EE+ G+ S+E
Sbjct: 216 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 275

Query: 567 EEDRKPKAEEDE 578
            E+ + + EE+E
Sbjct: 276 SEEEEEEEEEEE 287



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
           E ++    +   +EEEEE+EEE++ G   EE          EE++ E ++ + E     V
Sbjct: 266 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 325

Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
            +   DR   + +  E+E+   +P++
Sbjct: 326 PESRFDRDSGESEEAEEEVGEGTPQS 351



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 7/76 (9%)

Query: 524 VKEEEEEKE------EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEEEDRKPKAEE 576
           VKE+E E E      EE+DK   E E +++ E  ++ S  E D     + + +R+ K  E
Sbjct: 90  VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 149

Query: 577 DEILNRSPRNRKPRRE 592
            +   R  + R+ R E
Sbjct: 150 QQKEQREQKERERRAE 165


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           +++TS  E    ++     +EEEEE+EEE+++G   EE EE+ EE+++ + EE G    +
Sbjct: 228 ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 285

Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
             E    +  E+E+     R  +
Sbjct: 286 ASEQSAEEVSEEEMSEDEERENE 308



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
           S  +  S  E K + A     +     +EEE+++ +EEEEG   E+ EE+++ + EE+  
Sbjct: 219 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 278

Query: 562 TVSQEEEDRKPKAEE 576
           T S  EE  +  AEE
Sbjct: 279 TGSNSEEASEQSAEE 293



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
           SG       E ++ +  +    EE EE+EEE++  +EEEE     EE  +  AEE    V
Sbjct: 241 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 294

Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
           S+EE     + E +  L   P +R  R
Sbjct: 295 SEEEMSEDEERENENHLLVVPESRFDR 321



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
           ME +   +   D+ + E +    +    E   G E+ EE+++ + EE+G T  + EE+ +
Sbjct: 212 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 270

Query: 572 PKAEEDE 578
            + EE+E
Sbjct: 271 EEEEEEE 277



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
           E    E   G EEEE EE+ EE++ S +EE     S+EEE+ + + EE+   N    + +
Sbjct: 235 ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 289

Query: 589 PRRE 592
              E
Sbjct: 290 SAEE 293



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 18/72 (25%)

Query: 525 KEEEEEKEEEKD------------------KGDEEEEGEEKLEEKQKSDAEEDGGTVSQE 566
           K  +EEK EE+D                  +    E G    EE+++ + EE+ G+ S+E
Sbjct: 205 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 264

Query: 567 EEDRKPKAEEDE 578
            E+ + + EE+E
Sbjct: 265 SEEEEEEEEEEE 276



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
           E ++    +   +EEEEE+EEE++ G   EE          EE++ E ++ + E     V
Sbjct: 255 EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 314

Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
            +   DR   + +  E+E+   +P++
Sbjct: 315 PESRFDRDSGESEEAEEEVGEGTPQS 340



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 7/85 (8%)

Query: 515 KKTDAPQPDVKEEEEEKE------EEKDKGDEEEEGEEKLE-EKQKSDAEEDGGTVSQEE 567
           K+ +     VKE+E E E      EE+DK   E E +++ E  ++ S  E D     + +
Sbjct: 70  KRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERK 129

Query: 568 EDRKPKAEEDEILNRSPRNRKPRRE 592
            +R+ K  E +   R  + R+ R E
Sbjct: 130 RERERKMREQQKEQREQKERERRAE 154


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query: 506 KKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQ 565
           +++TS  E    ++     +EEEEE+EEE+++G   EE EE+ EE+++ + EE G    +
Sbjct: 17  ERKTSSAESSSAESGSGS-EEEEEEEEEEEEEGSTSEESEEE-EEEEEEEEEETGSNSEE 74

Query: 566 EEEDRKPKAEEDEILNRSPRNRK 588
             E    +  E+E+     R  +
Sbjct: 75  ASEQSAEEVSEEEMSEDEERENE 97



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG--EEKLEEKQKSDAEEDGG 561
           S  +  S  E K + A     +     +EEE+++ +EEEEG   E+ EE+++ + EE+  
Sbjct: 8   SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 67

Query: 562 TVSQEEEDRKPKAEE 576
           T S  EE  +  AEE
Sbjct: 68  TGSNSEEASEQSAEE 82



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 504 SGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTV 563
           SG       E ++ +  +    EE EE+EEE++  +EEEE     EE  +  AEE    V
Sbjct: 30  SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE--EEEEETGSNSEEASEQSAEE----V 83

Query: 564 SQEEEDRKPKAEEDEILNRSPRNRKPR 590
           S+EE     + E +  L   P +R  R
Sbjct: 84  SEEEMSEDEERENENHLLVVPESRFDR 110



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 512 MEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRK 571
           ME +   +   D+ + E +    +    E   G E+ EE+++ + EE+G T  + EE+ +
Sbjct: 1   MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEE-EEEEEEEEEEEGSTSEESEEEEE 59

Query: 572 PKAEEDE 578
            + EE+E
Sbjct: 60  EEEEEEE 66



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 529 EEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRK 588
           E    E   G EEEE EE+ EE++ S +EE     S+EEE+ + + EE+   N    + +
Sbjct: 24  ESSSAESGSGSEEEEEEEEEEEEEGSTSEE-----SEEEEEEEEEEEEETGSNSEEASEQ 78

Query: 589 PRRE 592
              E
Sbjct: 79  SAEE 82



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 12/86 (13%)

Query: 513 EYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEG---------EEKLEEKQKSDAEEDGGTV 563
           E ++    +   +EEEEE+EEE++ G   EE          EE++ E ++ + E     V
Sbjct: 44  EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV 103

Query: 564 SQEEEDR---KPKAEEDEILNRSPRN 586
            +   DR   + +  E+E+   +P++
Sbjct: 104 PESRFDRDSGESEEAEEEVGEGTPQS 129


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.135    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,098,096
Number of Sequences: 37866
Number of extensions: 1695441
Number of successful extensions: 37698
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 685
Number of HSP's successfully gapped in prelim test: 407
Number of HSP's that attempted gapping in prelim test: 12463
Number of HSP's gapped (non-prelim): 12707
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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