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Search of human proteins with 66792814
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66792814 retrotransposon gag domain containing 4 [Homo
sapiens]
(569 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 1157 0.0
gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens] 104 2e-22
gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens] 104 2e-22
gi|49355807 leucine zipper, down-regulated in cancer 1-like [Hom... 87 4e-17
gi|199562283 retrotransposon-like 1 [Homo sapiens] 85 2e-16
gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens] 79 9e-15
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 72 2e-12
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 71 3e-12
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 70 4e-12
gi|17975763 myelin transcription factor 1 [Homo sapiens] 70 5e-12
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 70 7e-12
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 69 1e-11
gi|55956788 nucleolin [Homo sapiens] 67 3e-11
gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens] 67 3e-11
gi|221219020 NYD-SP11 protein [Homo sapiens] 67 4e-11
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 67 4e-11
gi|148746195 trichohyalin [Homo sapiens] 66 7e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 65 1e-10
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 65 2e-10
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 65 2e-10
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 65 2e-10
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 65 2e-10
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 64 3e-10
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 64 3e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 64 4e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 63 6e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 63 6e-10
gi|6912480 leucine zipper, down-regulated in cancer 1 [Homo sapi... 63 6e-10
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 62 1e-09
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 62 1e-09
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 1157 bits (2993), Expect = 0.0
Identities = 569/569 (100%), Positives = 569/569 (100%)
Query: 1 MSEASGNLNSLRMANVALREELNALRGENANLGLQLGRALAEVNSLRGNVSSYIRWPVPI 60
MSEASGNLNSLRMANVALREELNALRGENANLGLQLGRALAEVNSLRGNVSSYIRWPVPI
Sbjct: 1 MSEASGNLNSLRMANVALREELNALRGENANLGLQLGRALAEVNSLRGNVSSYIRWPVPI 60
Query: 61 VPVLAEENLEFALSEIEVIPGGELPFLCRPPPRAEPDCISDDLLINVIQDRSTPDGPADP 120
VPVLAEENLEFALSEIEVIPGGELPFLCRPPPRAEPDCISDDLLINVIQDRSTPDGPADP
Sbjct: 61 VPVLAEENLEFALSEIEVIPGGELPFLCRPPPRAEPDCISDDLLINVIQDRSTPDGPADP 120
Query: 121 PLLPIPPPPALPPPASKEPPPQPPLAPLERPEIEPFSGDPVYLAEFLMQLETFIADHEVH 180
PLLPIPPPPALPPPASKEPPPQPPLAPLERPEIEPFSGDPVYLAEFLMQLETFIADHEVH
Sbjct: 121 PLLPIPPPPALPPPASKEPPPQPPLAPLERPEIEPFSGDPVYLAEFLMQLETFIADHEVH 180
Query: 181 FPGGAERVAFLISFFTGEAKDWAISVTQEGSPLHANFPRFLDEIRKEFCGPIPPRVAKKA 240
FPGGAERVAFLISFFTGEAKDWAISVTQEGSPLHANFPRFLDEIRKEFCGPIPPRVAKKA
Sbjct: 181 FPGGAERVAFLISFFTGEAKDWAISVTQEGSPLHANFPRFLDEIRKEFCGPIPPRVAKKA 240
Query: 241 IRKLKQGHCTLGSYADAFQFLAQFLSWDDCRLQNQFLKGLSEFFRKELLWSTEMADLDEL 300
IRKLKQGHCTLGSYADAFQFLAQFLSWDDCRLQNQFLKGLSEFFRKELLWSTEMADLDEL
Sbjct: 241 IRKLKQGHCTLGSYADAFQFLAQFLSWDDCRLQNQFLKGLSEFFRKELLWSTEMADLDEL 300
Query: 301 ILECVEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSK 360
ILECVEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSK
Sbjct: 301 ILECVEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSK 360
Query: 361 DQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGES 420
DQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGES
Sbjct: 361 DQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGES 420
Query: 421 KDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQ 480
KDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQ
Sbjct: 421 KDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQ 480
Query: 481 TSGPTSGYHAENFLGASPPIIQPSRRRNQNRVPLLEGLPGTNSPFYSSPQLIRRTGRLGQ 540
TSGPTSGYHAENFLGASPPIIQPSRRRNQNRVPLLEGLPGTNSPFYSSPQLIRRTGRLGQ
Sbjct: 481 TSGPTSGYHAENFLGASPPIIQPSRRRNQNRVPLLEGLPGTNSPFYSSPQLIRRTGRLGQ 540
Query: 541 RQVRRRPPVLFRLTPRQGGHRAARGRIRV 569
RQVRRRPPVLFRLTPRQGGHRAARGRIRV
Sbjct: 541 RQVRRRPPVLFRLTPRQGGHRAARGRIRV 569
>gi|94421473 paternally expressed 10 isoform RF1 [Homo sapiens]
Length = 325
Score = 104 bits (259), Expect = 2e-22
Identities = 73/234 (31%), Positives = 114/234 (48%), Gaps = 17/234 (7%)
Query: 135 ASKEPPPQPPLAPLERPEIEPFSGDPVYLAEFLMQLETFIADHEVHFPGGAERVAFLISF 194
A+ PPP P + PE F G+P LA F+ Q + F+ F RV F+ S
Sbjct: 67 AAAPPPPIEEECPEDLPE--KFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSM 124
Query: 195 FTGEAKDWAISVTQEGSPLHANFPRFLDEIRKEFCGPIPPRVAKKAIRKLKQGHCTLGSY 254
TG A WA + + L N+P F+ E++ F P VAK+ IR+L+QG ++ Y
Sbjct: 125 MTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLRQGMGSVIDY 184
Query: 255 ADAFQFLAQFLSWDDCRLQNQFLKGLSEFFRKELLWSTEMADLDELILECVEIERKV--- 311
++AFQ +AQ L W++ L +Q+ +GLS+ ++EL L LI +C+ IER++
Sbjct: 185 SNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCIHIERRLARA 244
Query: 312 ---RVPKPIPLPGVRNIIFPFAPS-----PNEEESEDEEYYSEDEDQEARRHRL 357
R P+ P R ++ P S P E +++E + R+ L
Sbjct: 245 AAARKPRSPP----RALVLPHIASHHQVDPTEPVGGARMRLTQEEKERRRKLNL 294
Score = 30.0 bits (66), Expect = 5.9
Identities = 22/101 (21%), Positives = 41/101 (40%), Gaps = 12/101 (11%)
Query: 373 MKEKEEEEMKKE-EEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGG 431
M E+ +E+ +E +++K K+ EE ++ + ++ N E EDED+D
Sbjct: 1 MTERRRDELSEEINNLREKVMKQSEENNNLQSQVQKLTEENTTLREQVEPTPEDEDDDIE 60
Query: 432 QKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEP 472
+ P P++E +DL E + P
Sbjct: 61 LRGAAAAAAPP-----------PPIEEECPEDLPEKFDGNP 90
>gi|94421475 paternally expressed 10 isoform RF1/2 [Homo sapiens]
Length = 708
Score = 104 bits (259), Expect = 2e-22
Identities = 73/234 (31%), Positives = 114/234 (48%), Gaps = 17/234 (7%)
Query: 135 ASKEPPPQPPLAPLERPEIEPFSGDPVYLAEFLMQLETFIADHEVHFPGGAERVAFLISF 194
A+ PPP P + PE F G+P LA F+ Q + F+ F RV F+ S
Sbjct: 67 AAAPPPPIEEECPEDLPE--KFDGNPDMLAPFMAQCQIFMEKSTRDFSVDRVRVCFVTSM 124
Query: 195 FTGEAKDWAISVTQEGSPLHANFPRFLDEIRKEFCGPIPPRVAKKAIRKLKQGHCTLGSY 254
TG A WA + + L N+P F+ E++ F P VAK+ IR+L+QG ++ Y
Sbjct: 125 MTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIRRLRQGMGSVIDY 184
Query: 255 ADAFQFLAQFLSWDDCRLQNQFLKGLSEFFRKELLWSTEMADLDELILECVEIERKV--- 311
++AFQ +AQ L W++ L +Q+ +GLS+ ++EL L LI +C+ IER++
Sbjct: 185 SNAFQMIAQDLDWNEPALIDQYHEGLSDHIQEELSHLEVAKSLSALIGQCIHIERRLARA 244
Query: 312 ---RVPKPIPLPGVRNIIFPFAPS-----PNEEESEDEEYYSEDEDQEARRHRL 357
R P+ P R ++ P S P E +++E + R+ L
Sbjct: 245 AAARKPRSPP----RALVLPHIASHHQVDPTEPVGGARMRLTQEEKERRRKLNL 294
Score = 32.0 bits (71), Expect = 1.6
Identities = 12/22 (54%), Positives = 12/22 (54%)
Query: 126 PPPPALPPPASKEPPPQPPLAP 147
PP P PPP PPP PP P
Sbjct: 682 PPVPQYPPPQPPPPPPPPPPPP 703
Score = 30.4 bits (67), Expect = 4.6
Identities = 13/23 (56%), Positives = 13/23 (56%)
Query: 114 PDGPADPPLLPIPPPPALPPPAS 136
P P PP P PPPP PPP S
Sbjct: 682 PPVPQYPPPQPPPPPPPPPPPPS 704
Score = 30.0 bits (66), Expect = 5.9
Identities = 22/101 (21%), Positives = 41/101 (40%), Gaps = 12/101 (11%)
Query: 373 MKEKEEEEMKKE-EEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGG 431
M E+ +E+ +E +++K K+ EE ++ + ++ N E EDED+D
Sbjct: 1 MTERRRDELSEEINNLREKVMKQSEENNNLQSQVQKLTEENTTLREQVEPTPEDEDDDIE 60
Query: 432 QKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEP 472
+ P P++E +DL E + P
Sbjct: 61 LRGAAAAAAPP-----------PPIEEECPEDLPEKFDGNP 90
Score = 30.0 bits (66), Expect = 5.9
Identities = 13/25 (52%), Positives = 14/25 (56%), Gaps = 3/25 (12%)
Query: 120 PPLLPIPPPPALPPPASKEPPPQPP 144
PP+ PPP PPP PPP PP
Sbjct: 682 PPVPQYPPPQPPPPPP---PPPPPP 703
>gi|49355807 leucine zipper, down-regulated in cancer 1-like [Homo
sapiens]
Length = 239
Score = 87.0 bits (214), Expect = 4e-17
Identities = 56/125 (44%), Positives = 70/125 (56%), Gaps = 8/125 (6%)
Query: 120 PPLLPIPPPPALPPPASKEPPPQPPLAPLERPEIEPFSGDPVYLAEFLMQLETFIADHEV 179
P L I PP + P PP + E PFSGDP LA FLMQ++ F+
Sbjct: 74 PGALQITPPISSITSNGTRPMTTPPTSLPE-----PFSGDPGRLAGFLMQMDRFMIFQAS 128
Query: 180 HFPGGAERVAFLISFFTGEAKDWAISVTQEGSPLHANFPRFLDEIRKEFCGPIPPRVAKK 239
FPG AERVAFL+S TGEA+ WAI Q SPL N+ FL E+R+ + P+ R A++
Sbjct: 129 RFPGEAERVAFLVSRLTGEAEKWAIPHMQPDSPLRNNYQGFLAELRRTYKSPL--RHARR 186
Query: 240 A-IRK 243
A IRK
Sbjct: 187 AQIRK 191
>gi|199562283 retrotransposon-like 1 [Homo sapiens]
Length = 1358
Score = 84.7 bits (208), Expect = 2e-16
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 4/187 (2%)
Query: 151 PEIEPFSGDPVYLAEFLMQLETFIADHEVHFPGGAERVAFLISFFTGEAKDWAISVTQEG 210
P + FSGD EF++ + + + F RV ++I+ +G A +WA ++ QE
Sbjct: 201 PAPKHFSGDRREFHEFIVLCQLTLQSYPRMFYNDRLRVGYVINHLSGLALEWAKALLQEN 260
Query: 211 SPLHANFPRFLDEIRKEFCGPIPPRVAKKAIRKLKQGHCTLGSYADAFQFLAQFLSWDDC 270
SPL +FP FL+ + + F RVA++A+ ++QG + Y D FQ L L W D
Sbjct: 261 SPLIGDFPAFLEAMSEVFEYRQALRVAEEAMFTIRQGGRSATEYIDEFQSLVPILGWPDE 320
Query: 271 RLQNQFLKGLSEFFRKELLWSTEMADLDELILECVEIERKVRVPKPI----PLPGVRNII 326
LQ +GL+E R L + LD LI+ ++IE K+ + + P RN+
Sbjct: 321 VLQAHLCQGLNEEIRHYLFRVPQPDSLDSLIVLILQIEEKLAERRAMLRLPPEARPRNLT 380
Query: 327 FPFAPSP 333
+ +P+P
Sbjct: 381 WIDSPAP 387
>gi|22749387 zinc finger, CCHC domain containing 5 [Homo sapiens]
Length = 475
Score = 79.3 bits (194), Expect = 9e-15
Identities = 54/164 (32%), Positives = 83/164 (50%), Gaps = 6/164 (3%)
Query: 156 FSGDPVYLAEFLMQLETFIADHEVHFPGGAERVAFLISFFTGEAKDWAISVTQEGSPLHA 215
FSGD L EFL+QL +++ +P A V+F+ + F+G A W + SPL
Sbjct: 244 FSGDSQKLPEFLVQLYSYMRVRGHLYPTEAALVSFVGNCFSGRAGWWFQLLLDIQSPLLE 303
Query: 216 NFPRFLDEIRKEFCGPIPPRVAKKAIRKLKQGHCTLGSYADAFQFLAQFLSWDDCRLQNQ 275
F+ ++ F P + A + I +L QG G A F +AQ L+WD+ L Q
Sbjct: 304 QCESFIPVLQDTFDNPENMKDANQCIHQLCQGE---GHVATHFHLIAQELNWDESTLWIQ 360
Query: 276 FLKGLSEFFRKELLWSTEMADLDELILECVEIERKVRVPKPIPL 319
F +GL+ + EL ++ +L +LI +C+ +E K P P PL
Sbjct: 361 FQEGLASSIQDELSHTSPATNLSDLITQCISLEEK---PDPNPL 401
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 71.6 bits (174), Expect = 2e-12
Identities = 58/184 (31%), Positives = 93/184 (50%), Gaps = 18/184 (9%)
Query: 331 PSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKK- 389
PSP E + E E E + + + +R++ R QQE +++ E+E +K+ EM+K
Sbjct: 499 PSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKE 558
Query: 390 -KEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEED----EDEDGGQKPEGEPQQDPGT 444
K+EKE+E E +QKE+E+E++ E+E E + E++ E++ ++P EP +
Sbjct: 559 RKQEKEKELE---RQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQE 615
Query: 445 EETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGP------TSGYHAENFLGASP 498
E EEEP+ QD + E E P VH + SG SGY + F + P
Sbjct: 616 SENSCNKEEEPVFTRQDSNRSE-KEATPV-VHETEPESGSQPRPAVLSGYF-KQFQKSLP 672
Query: 499 PIIQ 502
P Q
Sbjct: 673 PRFQ 676
Score = 58.2 bits (139), Expect = 2e-08
Identities = 41/170 (24%), Positives = 87/170 (51%), Gaps = 26/170 (15%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQR----------KRMRAFQQEMKEKEEEEMKKEEEMK 388
E+EE E++ + A +L D++ + +R ++E + + E+E++KE+E +
Sbjct: 467 EEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQE 526
Query: 389 KKEEKEEE-----------EEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGE 437
+++E+E++ E+E+ KQ+E E+E + + E+E E + E++++ ++ E E
Sbjct: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586
Query: 438 PQQDPGTEETYGEVEE-----EPLDEAQDDDLDELMEMEPTFVHASSQTS 482
+ + E+ ++E EP+ E Q+ + E EP F S S
Sbjct: 587 CELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRS 636
Score = 48.1 bits (113), Expect = 2e-05
Identities = 41/159 (25%), Positives = 78/159 (49%), Gaps = 26/159 (16%)
Query: 331 PSPNEEESEDEEYYSEDEDQEARRHR---LHSKDQRKRMRAFQQEMKEKEEEEMKKEEEM 387
P P++++ DE DE + RR + + + +R R R ++E + +E+ + E++
Sbjct: 431 PFPSKQQVADE-----DEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKL 485
Query: 388 KKKEEK--------------EEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQK 433
K+ +EK E E E K++E E+E+ + E+E E + E+D + ++
Sbjct: 486 KRLDEKLGILEKQPSPEEIRERERE---KEREREKELEKEQEQEREKEREKDRERQQEKE 542
Query: 434 PEGEPQQDPGTE-ETYGEVEEEPLDEAQDDDLDELMEME 471
E E +Q+ E E + E+E E Q + EL +M+
Sbjct: 543 KELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMK 581
Score = 34.3 bits (77), Expect = 0.32
Identities = 31/153 (20%), Positives = 60/153 (39%), Gaps = 5/153 (3%)
Query: 380 EMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEE-GESKDEEDEDEDGGQKPEGEP 438
E ++ + E KE ++ + + + +E + E + E + D+DE G P+
Sbjct: 290 EPERPSILSASELKELDKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENN 349
Query: 439 QQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENFLGASP 498
+D G++ + ++ DE + + +P+ V GP+ P
Sbjct: 350 SEDQGSKASENNENKKETDEVSNTKSSSQIPAQPS-VAKVPYGKGPSFNQERGTSSHLPP 408
Query: 499 PIIQPSRRRNQNRVPLLEGLPGTNSPFYSSPQL 531
P P Q+ P + +PG PF S Q+
Sbjct: 409 P---PKLLAQQHPPPDRQAVPGRPGPFPSKQQV 438
Score = 31.6 bits (70), Expect = 2.0
Identities = 26/108 (24%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ + E + E + + + R R +E + +++ +KK ++
Sbjct: 964 EEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRD 1023
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDP 442
+EE E ++KE+E E K E+ K E+ E +D P P Q P
Sbjct: 1024 MKEERE-QRKEKEGEKAEKVTEKVVVKPEKTEKKD--LPPPPPPPQPP 1068
Score = 29.6 bits (65), Expect = 7.8
Identities = 17/75 (22%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
Query: 385 EEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGT 444
E + KK++K ++EE K++E+ ++ NK ++ +E+ + P +Q G
Sbjct: 1683 EVVSKKQQKRLQDEERRKKEEQVIQVWNK-----KNANEKGRSQTSKLPPRFAKKQATGI 1737
Query: 445 EETYGEVEEEPLDEA 459
++ PL A
Sbjct: 1738 QQAQSSASVPPLASA 1752
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 70.9 bits (172), Expect = 3e-12
Identities = 37/102 (36%), Positives = 66/102 (64%), Gaps = 4/102 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK---E 391
E E +EE E + +E R+ + K+++K+ + ++ KEKEEEE K++ + KKK E
Sbjct: 15 ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKR-KEKEEEEKKRKRKRKKKKEEE 73
Query: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQK 433
E+EEEEEEE ++KEEEE+ + ++ + + ++E+E+ +K
Sbjct: 74 EREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Score = 70.1 bits (170), Expect = 5e-12
Identities = 42/114 (36%), Positives = 71/114 (62%), Gaps = 16/114 (14%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395
EE+E+ E E+E++E +R K++RK K KE+E+ KK +E +K++EKEE
Sbjct: 11 EETEETEETEEEEEKEGKR-----KEKRKE--------KRKEKEKKKKTKETEKRKEKEE 57
Query: 396 EEEE---EMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEE 446
EE++ + K+K+EEEE + EEE E K+EE+++E +K + + ++ EE
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111
Score = 59.7 bits (143), Expect = 7e-09
Identities = 28/92 (30%), Positives = 61/92 (66%)
Query: 370 QQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDED 429
+++ K+KE EE ++ EE +++EEKE + +E+ K+K +E+E + K +E + K++E+E++
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 430 GGQKPEGEPQQDPGTEETYGEVEEEPLDEAQD 461
+K + + +++ EE E EE+ +E ++
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93
Score = 57.8 bits (138), Expect = 3e-08
Identities = 31/91 (34%), Positives = 61/91 (67%), Gaps = 5/91 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
+E+ +++E + ++ E R+ + + +RKR R ++E +E+EEEE ++EEE K++EEKE
Sbjct: 34 KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE-KEEEEKE 92
Query: 395 E----EEEEEMKQKEEEEEIRNKNEEEGESK 421
E +++++ ++KEEEEE + K + + K
Sbjct: 93 EGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 56.2 bits (134), Expect = 8e-08
Identities = 31/111 (27%), Positives = 64/111 (57%), Gaps = 6/111 (5%)
Query: 350 QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEE 409
++ ++ + +++ + ++E KE + +E +KE+ +K+++K+ +E E+ K+KEEEE+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 410 IR------NKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
R K EEE E ++EE+E+E ++ E ++ + E EEE
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111
Score = 55.8 bits (133), Expect = 1e-07
Identities = 29/92 (31%), Positives = 58/92 (63%)
Query: 375 EKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKP 434
+K++++ K+ EE ++ EE EEEEE+E K+KE+ +E R + E++ ++K+ E E ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 435 EGEPQQDPGTEETYGEVEEEPLDEAQDDDLDE 466
+ + ++ EE E EEE +E ++++ E
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92
Score = 47.4 bits (111), Expect = 4e-05
Identities = 23/90 (25%), Positives = 55/90 (61%)
Query: 382 KKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQD 441
KK+++ KK+ E+ EE EE +++E+E + + K +E+ + K+++ + ++ ++ E E ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 442 PGTEETYGEVEEEPLDEAQDDDLDELMEME 471
+ + EEE +E ++++ +E E E
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEE 90
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 70.5 bits (171), Expect = 4e-12
Identities = 40/125 (32%), Positives = 74/125 (59%), Gaps = 11/125 (8%)
Query: 331 PSPNEEESEDEEYYSEDED--------QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMK 382
P E+ E +E E E+ Q+ + R K Q ++M+ +++M+E+EE +
Sbjct: 77 PEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWE 136
Query: 383 KEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEE-EGESKDEEDEDEDGGQKPEGEPQQD 441
+EE+M+++EEK E+EE+M+ E+EE++R + E+ +G+ + D + GG+ EG PQ +
Sbjct: 137 QEEKMQEQEEKMWEQEEKMR--EQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDN 194
Query: 442 PGTEE 446
P +E
Sbjct: 195 PTAQE 199
Score = 57.0 bits (136), Expect = 5e-08
Identities = 35/129 (27%), Positives = 70/129 (54%), Gaps = 3/129 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE + E +E++ R ++Q ++MR +++M E+EE+ ++EE+M ++EEK
Sbjct: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGE---SKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
E+EE+M +++ E + K E+ E K+E ++ Q+ E ++ EE E
Sbjct: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
Query: 452 EEEPLDEAQ 460
EE+ ++ +
Sbjct: 124 EEKMQEQEE 132
Score = 55.5 bits (132), Expect = 1e-07
Identities = 36/132 (27%), Positives = 74/132 (56%), Gaps = 3/132 (2%)
Query: 341 EEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEE 400
EE + +++ R ++Q ++M+ +++M+E+EE+ ++EE+M+++EEK E+EE+
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 401 MKQKEEEEEIRNKNEEEGESKDEEDE--DEDGGQKPEGEPQQDPGTEETYGEVEEEPLDE 458
M ++EE+ + + E+ E E+DE E + E + Q + +EE + E
Sbjct: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122
Query: 459 AQDDDLDELMEM 470
Q++ + E EM
Sbjct: 123 -QEEKMQEQEEM 133
Score = 54.7 bits (130), Expect = 2e-07
Identities = 32/114 (28%), Positives = 64/114 (56%), Gaps = 3/114 (2%)
Query: 363 RKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKD 422
R+ R ++E K +EEEEM +E+E K +E++E+ E+E K E+EE+++ + E+ E ++
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 423 EEDEDEDGGQKPEGEPQQDP---GTEETYGEVEEEPLDEAQDDDLDELMEMEPT 473
+ E E+ + + P+Q +E E EE ++ ++++ E + T
Sbjct: 62 KMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKT 115
Score = 49.3 bits (116), Expect = 9e-06
Identities = 32/148 (21%), Positives = 76/148 (51%), Gaps = 11/148 (7%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKE-KEEEEMKKEEEMKKKEEK 393
E+E + +E + +QE + K Q + + ++QE K ++EE+M +++ + +++EK
Sbjct: 23 EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK 82
Query: 394 EEEEEEEMKQKEEE----------EEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPG 443
E++E +++KEE E++R K + + E E++E ++ E ++
Sbjct: 83 MWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQ 142
Query: 444 TEETYGEVEEEPLDEAQDDDLDELMEME 471
+E +EE + E ++ ++ +M+
Sbjct: 143 EQEEKMWEQEEKMREQEEKMREQEEKMQ 170
Score = 48.9 bits (115), Expect = 1e-05
Identities = 30/124 (24%), Positives = 65/124 (52%), Gaps = 2/124 (1%)
Query: 348 EDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEE 407
E++ R +++ + MR +QE K +E+EE +E+E K E++E+ +E+E K E+E
Sbjct: 3 EEERMREREKKMREEEEMMR--EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 408 EEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDEL 467
E++ + E+ E + ++ E ++ E +++ E + E + E + +++
Sbjct: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
Query: 468 MEME 471
E E
Sbjct: 121 QEQE 124
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/96 (33%), Positives = 57/96 (59%), Gaps = 8/96 (8%)
Query: 381 MKKEEEMKKKEEKEEEEEEEMKQKEE-----EEEIRNKNEE--EGESKDEEDEDEDGGQK 433
M++EE M+++E+K EEEE M+++EE EE++R + E+ E E K +E E++ Q+
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 434 PEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELME 469
+ Q++ E+ ++E + E QD+ L E E
Sbjct: 61 EKMWEQEEKMWEQQRLPEQKEKMWE-QDERLREKEE 95
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 70.1 bits (170), Expect = 5e-12
Identities = 45/138 (32%), Positives = 72/138 (52%), Gaps = 5/138 (3%)
Query: 331 PSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK 390
P EE E S+D ++ + +++ +E E+EEEE ++EEE +++
Sbjct: 218 PEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEE 277
Query: 391 EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKD----EEDEDEDGGQK-PEGEPQQDPGTE 445
EE+EEEEEEE +++EEEEE + EEE E+ +ED QK PE + P +
Sbjct: 278 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPK 337
Query: 446 ETYGEVEEEPLDEAQDDD 463
Y + E D+ +D+D
Sbjct: 338 PEYSVIVEVRSDDDKDED 355
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/132 (25%), Positives = 69/132 (52%), Gaps = 9/132 (6%)
Query: 359 SKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEG 418
S++ K + ++ +E E ++ +++ + ++ EE KQK I + EE+
Sbjct: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKG----ILSHEEEDE 262
Query: 419 ESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHAS 478
E ++EE+E+E+ ++ E E +++ EE E EEE +E +++ +++ E T H S
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT-SHTS 321
Query: 479 SQTS----GPTS 486
+Q + GP S
Sbjct: 322 AQKAPELRGPES 333
Score = 33.9 bits (76), Expect = 0.41
Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKE----EEMKKK 390
EEE E+EE E+E++EA + +D E++ E K E E++
Sbjct: 290 EEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSD 349
Query: 391 EEKEEEEEEEMKQKEEEEEIRN 412
++K+E+ +E E+++
Sbjct: 350 DDKDEDTHSRKSTVTDESEMQD 371
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 69.7 bits (169), Expect = 7e-12
Identities = 53/151 (35%), Positives = 83/151 (54%), Gaps = 10/151 (6%)
Query: 331 PSPNEEE-SEDEEYYSED--EDQEARRHRLHSKDQRKRMR-AFQQEMKEKEEEEM-KKEE 385
P E+E +E EE+ D E ++ R + H K++ + M ++E E EEEE ++EE
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
Query: 386 EMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEG--ESKDEEDEDEDGGQKPEGE---PQQ 440
E K+ E KEE E EE++ + E+EE K EE E K EE+ D+ G++ E E ++
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEK 808
Query: 441 DPGTEETYGEVEEEPLDEAQDDDLDELMEME 471
+ G E GEVEE + ++++ E E E
Sbjct: 809 EEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Score = 68.9 bits (167), Expect = 1e-11
Identities = 52/144 (36%), Positives = 76/144 (52%), Gaps = 17/144 (11%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEM---KEKEEEEMKKEEEMKKKE 391
E E EE + E E++E R K+ + +E+ +EKEE E KKEE K E
Sbjct: 726 EMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGK-E 784
Query: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEG---------ESKDEEDEDEDGGQKPEGEPQQDP 442
EK EEE ++ + +EEE E R + +EEG E K E +E+E+ G EGE ++
Sbjct: 785 EKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG---EGEEEEGE 841
Query: 443 GTEETYGEVEEEPLDEAQDDDLDE 466
G EE GE EEE + +++ +E
Sbjct: 842 GEEEE-GEGEEEEGEGKGEEEGEE 864
Score = 68.9 bits (167), Expect = 1e-11
Identities = 45/133 (33%), Positives = 72/133 (54%), Gaps = 4/133 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKD----QRKRMRAFQQEMKEKEEEEMKKEEEMKKK 390
EE+ E+E E E++E ++ + + + E +E+EEE +EEE + +
Sbjct: 784 EEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGE 843
Query: 391 EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGE 450
EE+ E EEEE + K EEE + EEEGE + E E+E+G + E E + + EE GE
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903
Query: 451 VEEEPLDEAQDDD 463
EEE E ++++
Sbjct: 904 GEEEGEGEGEEEE 916
Score = 67.4 bits (163), Expect = 3e-11
Identities = 51/142 (35%), Positives = 72/142 (50%), Gaps = 13/142 (9%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EEE E EE E E++E ++ + ++ E EEEE + E E + + E E
Sbjct: 837 EEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE 896
Query: 395 EEE-----EEEMKQKEEEEEIRNKNEEEGES---KDEEDEDEDGGQKPEGEPQQDPG--- 443
EEE EEE + + EEEE K EEEGE + EE+E E G+ EGE +++ G
Sbjct: 897 EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE 956
Query: 444 --TEETYGEVEEEPLDEAQDDD 463
EE GE EEE E ++ +
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGE 978
Score = 66.6 bits (161), Expect = 6e-11
Identities = 53/153 (34%), Positives = 79/153 (51%), Gaps = 24/153 (15%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRM-RAFQQEMKEKEEEEMKKEEEMK--KKE 391
EEE ++ E E E +E R + +RK+ RA ++E E+E ++ + EEE + E
Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGE 806
Query: 392 EKEE-------EEEEEMKQKEEEEEIRNKNEEEGESKDEEDE---------DEDGGQKPE 435
EKEE E EE ++EEEEE EEEGE ++EE E E+ G++ E
Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866
Query: 436 GEPQQDPG-----TEETYGEVEEEPLDEAQDDD 463
GE + + G EE GE EEE E ++++
Sbjct: 867 GEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899
Score = 66.6 bits (161), Expect = 6e-11
Identities = 43/127 (33%), Positives = 70/127 (55%), Gaps = 7/127 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E E E+EE E+E+ E +++ + ++ + + EEE ++ E ++EE E
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDE----DEDGGQKPEGEPQQDPGT---EET 447
E EEE + + EEEE + EEEGE + EE+E E+ G++ EGE +++ G E+
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 448 YGEVEEE 454
GE EEE
Sbjct: 945 EGEGEEE 951
Score = 63.9 bits (154), Expect = 4e-10
Identities = 44/135 (32%), Positives = 72/135 (53%), Gaps = 3/135 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EEE E E E E + +++ + ++E +E E E ++E E + ++ +
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKG-EEEGEEGEGEGEEEEGEGEGEDGEG 946
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTE--ETYGEVE 452
E EEEE + + EEEE + EEEGE + EE E E ++ EGE +++ G E E GE E
Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 453 EEPLDEAQDDDLDEL 467
EE E ++++ E+
Sbjct: 1007 EEGEGEGEEEEEGEV 1021
Score = 63.5 bits (153), Expect = 5e-10
Identities = 49/157 (31%), Positives = 81/157 (51%), Gaps = 21/157 (13%)
Query: 335 EEESEDEEYYSEDEDQEARRHR--------------LHSKDQRKRMRAFQQEMKEKEEEE 380
EE S E++ ++E ++ + + L K++ K+ +QE KE+E+
Sbjct: 660 EEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGH 719
Query: 381 MKKE----EEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEG 436
K+ EE ++E E EEEE +++EEE+E K E EGE + E E E+G +K E
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779
Query: 437 EP-QQDPGTEE-TYGEVEEEPLDEAQDDDLDELMEME 471
+++ G EE GE EEE E + ++ +E E+E
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEE-TEGRGEEKEEGGEVE 815
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/151 (33%), Positives = 77/151 (50%), Gaps = 14/151 (9%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK--EE 392
E E++E E E E + +++ + ++E + +EEE +EEE + K EE
Sbjct: 802 EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEE 861
Query: 393 KEE----EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDE-DGGQKPEGEPQQDPGT--- 444
EE EE EE + + EEEE + EEEGE + EE+E E +G ++ EGE +++ G
Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKG 921
Query: 445 ----EETYGEVEEEPLDEAQDDDLDELMEME 471
EE GE EEE + +D E E E
Sbjct: 922 EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE 952
Score = 60.1 bits (144), Expect = 5e-09
Identities = 47/134 (35%), Positives = 68/134 (50%), Gaps = 7/134 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E E E+EE E E+ E + + K ++ E EEEE + E E + E +E
Sbjct: 892 EGEGEEEEGEGEGEE-EGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEE 950
Query: 395 EEEEEEMKQKEEEEEIRNKNE---EEGESKDEEDEDEDGGQKPEGEPQ---QDPGTEETY 448
EE E E +++E E E + E EEGE + EE+E E G++ EGE + + G EE
Sbjct: 951 EEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGE 1010
Query: 449 GEVEEEPLDEAQDD 462
GE EEE E + +
Sbjct: 1011 GEGEEEEEGEVEGE 1024
Score = 60.1 bits (144), Expect = 5e-09
Identities = 39/129 (30%), Positives = 66/129 (51%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E E E E+ E E++E + + + + E +E E E ++E E + +EE+
Sbjct: 936 EGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEG 995
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
EEE EE + EEE E + EEEGE + E + +E G+ E E +++ E GE EE
Sbjct: 996 EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055
Query: 455 PLDEAQDDD 463
+ ++++
Sbjct: 1056 RRNREEEEE 1064
Score = 60.1 bits (144), Expect = 5e-09
Identities = 41/137 (29%), Positives = 68/137 (49%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E E E+ E+ E+E+ E + + ++E E E EE + EEE +++ E E
Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
EE E E +++EE E EEGE + EE+E E+ G++ E E + + E EEE
Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 455 PLDEAQDDDLDELMEME 471
+ ++ +E + E
Sbjct: 1067 GKYQETGEEENERQDGE 1083
Score = 58.2 bits (139), Expect = 2e-08
Identities = 49/144 (34%), Positives = 73/144 (50%), Gaps = 15/144 (10%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKE---EEEMKKEEEMKKKE 391
EEE E+ E E E+ E + + + + E +E E EEE + E E ++ E
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918
Query: 392 EKEEEEEEEMKQKEEEEEIRNKNE--------EEGESKDEEDEDE-DGGQKPEGEPQQDP 442
K EEE EE + + EEEE + E EEGE + EE+E E +G ++ EGE ++
Sbjct: 919 GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE 978
Query: 443 G---TEETYGEVEEEPLDEAQDDD 463
G EE GE EEE +E +++
Sbjct: 979 GEGEEEEGEGEGEEEEGEEEGEEE 1002
Score = 57.0 bits (136), Expect = 5e-08
Identities = 41/150 (27%), Positives = 75/150 (50%), Gaps = 4/150 (2%)
Query: 335 EEESEDEEYYSEDEDQ---EARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKE 391
E E E+EE E E++ E +++ ++E +E+ EEE + EEE + +
Sbjct: 954 EWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEG 1013
Query: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
E+EEE E E + + EE E + EEEGE + EE E E G++ +++ E Y E
Sbjct: 1014 EEEEEGEVEGEVEGEEGEGEGE-EEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072
Query: 452 EEEPLDEAQDDDLDELMEMEPTFVHASSQT 481
EE + ++ ++ +++ + + +T
Sbjct: 1073 GEEENERQDGEEYKKVSKIKGSVKYGKHKT 1102
Score = 53.9 bits (128), Expect = 4e-07
Identities = 45/133 (33%), Positives = 66/133 (49%), Gaps = 19/133 (14%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EEE E+ E E+E+ E + E E E EE + E E +++E +
Sbjct: 922 EEEGEEGEGEGEEEEGEG-----------------EGEDGEGEGEEEEGEWEGEEEEGEG 964
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQ-QDPGTEETYGEVEE 453
E EEE + EE E + E EGE ++EE E E+G ++ EGE + + G EE GEVE
Sbjct: 965 EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE-EEGEEEGEGEEEGEGEGEEEEEGEVEG 1023
Query: 454 EPLDEAQDDDLDE 466
E E + + +E
Sbjct: 1024 EVEGEEGEGEGEE 1036
Score = 35.8 bits (81), Expect = 0.11
Identities = 25/106 (23%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E E E EE E+E +E + +++R R E+EEEE K +E ++E +
Sbjct: 1029 EGEGEGEEEEGEEEGEEREKEGEGEENRRNR---------EEEEEEEGKYQETGEEENER 1079
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
++ EE K + + ++ + + K + +G ++ P Q
Sbjct: 1080 QDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQ 1125
Score = 34.7 bits (78), Expect = 0.24
Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 5/112 (4%)
Query: 336 EESEDEEYYSEDEDQEARRHRLH-SKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E + +EY E +E + + H S+ A E EE E+ +E+E + +
Sbjct: 540 ENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGN 599
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGE--SKDEEDEDE--DGGQKPEGEPQQDP 442
EE+E++ EE ++ +E+ E S D D+ E +G K GE + P
Sbjct: 600 GIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGP 651
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 68.9 bits (167), Expect = 1e-11
Identities = 31/127 (24%), Positives = 80/127 (62%), Gaps = 1/127 (0%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ + +E +++++ R+ +Q ++++ +++++++EE+ K+EE+M+++EE+
Sbjct: 212 EEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQM 271
Query: 395 EEEEEEM-KQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE 453
E+EE+M KQKE+ E+ E+E + +++E++ + ++ + +Q EE G+ EE
Sbjct: 272 REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEE 331
Query: 454 EPLDEAQ 460
+ ++ +
Sbjct: 332 QMWEQKE 338
Score = 68.6 bits (166), Expect = 2e-11
Identities = 34/116 (29%), Positives = 73/116 (62%), Gaps = 3/116 (2%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEE 398
E EE E E+Q ++ +Q ++MR +++M E+EE+ K+EE+++K+EE+ ++E
Sbjct: 203 EQEEQMGEQEEQMQKQEE-QMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
Query: 399 EEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
E+M +E+EE++R + E+ + K++ +++E G++ E +Q+ E ++ E+
Sbjct: 262 EQM--REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315
Score = 65.9 bits (159), Expect = 1e-10
Identities = 38/141 (26%), Positives = 83/141 (58%), Gaps = 6/141 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEM-KKKEEK 393
EE+ +E +++++ ++ + Q ++MR +++M+E+EE+ ++EE+M K+KE+
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 394 EEEE---EEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGE 450
E+EE E+E + +E+EE++R + E+ E +++ E E+ Q + E Q E+ + +
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE--QMGKQEEQMWEQKEQMWEQ 343
Query: 451 VEEEPLDEAQDDDLDELMEME 471
E+ E Q + +E M+ +
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQ 364
Score = 64.3 bits (155), Expect = 3e-10
Identities = 38/142 (26%), Positives = 82/142 (57%), Gaps = 16/142 (11%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
+E++E EE E E+Q R ++Q ++MR +++M+E+EE+ K+EE+M +++E+
Sbjct: 282 KEQTEQEEQTGEQEEQ-MREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
Query: 395 EEEEEEMKQKEE------------EEEIRNKNEEEGESKDEEDEDEDGGQKPE---GEPQ 439
E++E+M ++EE EE++R + E+ + +++ + E+ +K E GE +
Sbjct: 341 WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
Query: 440 QDPGTEETYGEVEEEPLDEAQD 461
+ G ++ +EE + E ++
Sbjct: 401 EQMGEQKEQMREQEEQMGEQKE 422
Score = 63.5 bits (153), Expect = 5e-10
Identities = 34/138 (24%), Positives = 79/138 (57%), Gaps = 2/138 (1%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSK--DQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEE 392
E+E + E + +QE + + +Q ++M+ +++M E+EE+ K+EE+M ++EE
Sbjct: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE 241
Query: 393 KEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
+ +++EE+++++EE+ + + E E + E E++ QK + E ++ G +E +
Sbjct: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
Query: 453 EEPLDEAQDDDLDELMEM 470
EE + E ++ ++ +M
Sbjct: 302 EEQMREQEEQMREQEEQM 319
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/126 (30%), Positives = 76/126 (60%), Gaps = 12/126 (9%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ ++E ++++ + +Q+++M +++M E+EE+ K+EE+++K+EE+
Sbjct: 316 EEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQM 375
Query: 395 EEEEEEM-KQKE----EEEEIRNKNEEEGESKDE--EDEDEDGGQKPEGEPQQDPGTEET 447
++EE+M KQ+E +EE++ + E+ GE K++ E E++ G QK + Q EE
Sbjct: 376 RKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQ-----EEH 430
Query: 448 YGEVEE 453
GE +E
Sbjct: 431 MGEQKE 436
Score = 62.0 bits (149), Expect = 1e-09
Identities = 37/140 (26%), Positives = 75/140 (53%), Gaps = 3/140 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E + ++E +++ + R ++Q +M + +M E+EE+ ++EE+M+K+EE+
Sbjct: 163 EGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQM 222
Query: 395 EEEEEEMKQKEE---EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
E+EE+M+++EE E+E + + +EE K EE + Q E E Q E+ +
Sbjct: 223 GEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK 282
Query: 452 EEEPLDEAQDDDLDELMEME 471
E+ +E + +++ E E
Sbjct: 283 EQTEQEEQTGEQEEQMREQE 302
Score = 59.7 bits (143), Expect = 7e-09
Identities = 35/136 (25%), Positives = 77/136 (56%), Gaps = 6/136 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E + ++E +++ + R ++Q ++R + +M E+E + ++EE+M ++EE+
Sbjct: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQM 215
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPE----GEPQQDPGTEETYGE 450
+++EE+M E+EE++R + E+ GE +++ + E+ QK E + +Q EE E
Sbjct: 216 QKQEEQMG--EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE 273
Query: 451 VEEEPLDEAQDDDLDE 466
EE+ L + + + +E
Sbjct: 274 QEEQMLKQKEQTEQEE 289
Score = 59.7 bits (143), Expect = 7e-09
Identities = 38/145 (26%), Positives = 82/145 (56%), Gaps = 15/145 (10%)
Query: 335 EEESEDEEYYSEDEDQ-----EARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKK 389
E+ E EE E E+Q E + +Q ++MR +++M+E+EE+ ++EE+M++
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 390 KEEKEEEEEEEMKQK-----EEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGT 444
+EE+ ++EE+M ++ E++E++ + E+ GE +++ + E+ +K E + ++
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ--- 378
Query: 445 EETYGEVEEEPLDEAQDDDLDELME 469
EE + EE+ Q++ + E E
Sbjct: 379 EEQMRKQEEQM--RKQEEQMGEQKE 401
Score = 58.2 bits (139), Expect = 2e-08
Identities = 50/189 (26%), Positives = 97/189 (51%), Gaps = 20/189 (10%)
Query: 271 RLQNQFLKGLSEFFRKEL-LWSTEMADLDELILECVEIERKVRVPKPIPLPGVRNIIFPF 329
R+ N+ LK + ++EL L TE +++ L E++RK+ K IPLP +
Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEIQ---LHIKELKRKLETDK-IPLPQEGQV---- 54
Query: 330 APSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKK 389
E+E + E + +QE + + + + + +QE + +E+E +E+E +
Sbjct: 55 ----REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 110
Query: 390 KEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDE-DEDGGQKPEGEPQ---QDPGTE 445
+E++ + E+E + +E+E ++R E+EG+ +++E + E GQ E E Q Q+
Sbjct: 111 REQEGQVREQEGQVREQEGQVR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 446 ETYGEVEEE 454
E G+V E+
Sbjct: 168 EQEGQVREQ 176
Score = 53.9 bits (128), Expect = 4e-07
Identities = 39/141 (27%), Positives = 70/141 (49%), Gaps = 7/141 (4%)
Query: 335 EEESEDEEYYSEDEDQ--EARRHRLHSKDQ--RKRMRAFQQEMKEKEEEEMKKEEEMKKK 390
E+ + EE E E+Q E L K+Q ++ Q+E ++EE+M+++EE ++
Sbjct: 255 EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314
Query: 391 EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGE 450
+E++ E+EE K+EE+ K E+ E K++ + E+ Q E E Q E+ +
Sbjct: 315 QEEQMREQEEQMGKQEEQMWEQK-EQMWEQKEQMWKQEE--QMGEQEEQMQKQEEQVRKQ 371
Query: 451 VEEEPLDEAQDDDLDELMEME 471
E+ E Q +E M +
Sbjct: 372 EEQMRKQEEQMRKQEEQMRKQ 392
Score = 49.3 bits (116), Expect = 9e-06
Identities = 33/158 (20%), Positives = 83/158 (52%), Gaps = 11/158 (6%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E + ++E +++ + R ++Q ++R + +++E+E + ++E +++++E +
Sbjct: 128 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
Query: 395 EEEEEEMKQKE----EEEEIRNKNEEEGESKDEE-DEDEDGGQKPE---GEPQQDPGTEE 446
E+E +M ++E E+EE + EE+ + ++E+ E E+ +K E GE ++ +E
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
Query: 447 TYGEVEEEPL---DEAQDDDLDELMEMEPTFVHASSQT 481
+ +EE + +E + +++ E E + QT
Sbjct: 248 EQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/130 (20%), Positives = 74/130 (56%), Gaps = 5/130 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E + ++E +++ + R ++Q ++R + +++E+E + ++E +++++E +
Sbjct: 100 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 159
Query: 395 EEEEEEMKQKEEE--EEIRNKNEEEGESKDEEDE-DEDGGQKPEGEPQQDPGTEETYGEV 451
E+E +++++E + E+ E+EG+ +++E + E GQ GE ++ G +E +
Sbjct: 160 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQM--GEQEEQMGEQEEQMQK 217
Query: 452 EEEPLDEAQD 461
+EE + E ++
Sbjct: 218 QEEQMGEQEE 227
Score = 47.0 bits (110), Expect = 5e-05
Identities = 26/130 (20%), Positives = 74/130 (56%), Gaps = 5/130 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E + ++E +++ + R ++Q ++R + +++E+E + ++E +++++E +
Sbjct: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 173
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDE--EDEDEDGGQKPEGEPQQDP-GTEETYGEV 451
E+E ++ +E+E ++R + + GE + + E E++ G Q+ + + Q++ G +E
Sbjct: 174 REQEGQV--REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRK 231
Query: 452 EEEPLDEAQD 461
+EE + E ++
Sbjct: 232 QEEQMGEQEE 241
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 67.4 bits (163), Expect = 3e-11
Identities = 47/180 (26%), Positives = 84/180 (46%), Gaps = 7/180 (3%)
Query: 317 IPLPGVRNIIFPFAPSPNEEESED-EEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKE 375
IP G +N +EEE +D EE +DED++ + + A E ++
Sbjct: 129 IPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDED 188
Query: 376 KEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEE----IRNKNEEEGESKDEEDEDEDGG 431
E++E ++++ ++++ EEE E K ++ ++ KN E E ++E+DEDED
Sbjct: 189 DEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDD 248
Query: 432 QKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME--PTFVHASSQTSGPTSGYH 489
+ E D EE E EEEP+ EA E+ + + P + + PT+ ++
Sbjct: 249 DDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFN 308
Score = 50.8 bits (120), Expect = 3e-06
Identities = 32/165 (19%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 330 APSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKK 389
AP+ +E+ ED+E +D+D E + + M + K+ + K + + +
Sbjct: 181 APASEDEDDEDDEDDEDDDDDE------EDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234
Query: 390 KEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYG 449
E++EE++E+E +E++E +++E + ++EE+E+E+ ++ G+ +++ ++
Sbjct: 235 DEDEEEDDEDEDDDDDEDDE---DDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAP 291
Query: 450 EVEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENFL 494
E +++ ++ + L F ++ + S A+N L
Sbjct: 292 EAKKQKVEGTEPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDL 336
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 382 KKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDE-EDEDEDGGQKPEGEPQQ 440
KK + K K + ++ EEE++ ++EE+ E +DE EDE E K
Sbjct: 124 KKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPA 183
Query: 441 DPGTEETYGEVEEEPLDEAQDDDLDELMEMEP 472
++ E +E+ D+ +DD +E ME P
Sbjct: 184 SEDEDDEDDEDDEDDDDDEEDDSEEEAMETTP 215
>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
Length = 1388
Score = 67.4 bits (163), Expect = 3e-11
Identities = 61/227 (26%), Positives = 94/227 (41%), Gaps = 7/227 (3%)
Query: 130 ALPPPASKEPPPQPPLAPLERPEIEPFSGDPVYLAEFLMQLETFIADHEVHFPG---GAE 186
A P +K PP + P + P + + E D E G +E
Sbjct: 1125 ATTPETAKPPPKEVPSFGMLTPALCYLLEEQEAARGSCSVEEEMEIDEEKQMKGFLDDSE 1184
Query: 187 RVAFLISFFTGEAKDWAISVTQEGSPLHANFPRFLDEIRKEFCGPIPPRVAKKAIRKLKQ 246
R+AFL+S G A+ W I + G PL FL + + + + KQ
Sbjct: 1185 RMAFLVSLHLGAAERWFILQMEVGEPLSHENKSFLRRSQGIYDSLSEIDILSAVLCHPKQ 1244
Query: 247 GHCTLGSYADAFQFLAQFLSWDDCRLQNQFLKGLSEFFRKEL--LWSTEMADLDELILEC 304
G ++ YA F LA+ LSW D L+ +FL+GLSE ++ ++ L ELI
Sbjct: 1245 GQKSVRQYATDFLLLARHLSWSDAILRTRFLEGLSEAVTTKMGRIFLKVAGSLKELIDRS 1304
Query: 305 VEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQE 351
+ E ++ K PG + + P A N EE+ E S+ + +E
Sbjct: 1305 LYTECQLAEEK--DSPGNSSQVLPTACKRNNEEAMGNELSSQQQTEE 1349
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 67.0 bits (162), Expect = 4e-11
Identities = 41/143 (28%), Positives = 82/143 (57%), Gaps = 6/143 (4%)
Query: 332 SPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKE 391
S +E E EE++SE+ + L + +++ + ++E + +EEEE ++EE +++E
Sbjct: 2214 SSQVDEVESEEHFSEEMES------LLDELEKQESLSSEEEEEREEEEEREEEEVREEEE 2267
Query: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
E++EEEE E KQ E+EEE + K ++E + ++ ++++E +K E +++ + E
Sbjct: 2268 ERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEE 2327
Query: 452 EEEPLDEAQDDDLDELMEMEPTF 474
EE E + D E+++ E F
Sbjct: 2328 EESCSLEEEVDREKEILKKEKQF 2350
Score = 65.1 bits (157), Expect = 2e-10
Identities = 39/131 (29%), Positives = 69/131 (52%), Gaps = 13/131 (9%)
Query: 341 EEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEE 400
E++ S+ ++ E+ H F +EM+ +E K+E ++EE+ EEEEE
Sbjct: 2211 EKFSSQVDEVESEEH-------------FSEEMESLLDELEKQESLSSEEEEEREEEEER 2257
Query: 401 MKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQ 460
+++ EEE K EEEGE K E E+E+ +K + + +++ +E E +EE + E +
Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEE 2317
Query: 461 DDDLDELMEME 471
+ L + E E
Sbjct: 2318 TESLSDEEEEE 2328
Score = 61.6 bits (148), Expect = 2e-09
Identities = 38/122 (31%), Positives = 75/122 (61%), Gaps = 4/122 (3%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEE--MKKKEEK 393
+E E +E S +E++E +++ + ++E +E EE++++KEEE KKK+EK
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 394 EEEEEEEMKQK-EEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
++EE +E ++ EE+EEI ++ E E S DEE+E+E + E + +++ +E +++
Sbjct: 2295 KKEEVQEKEEVFEEKEEIMSEEETESLS-DEEEEEESCSLEEEVDREKEILKKEKQFKLQ 2353
Query: 453 EE 454
E+
Sbjct: 2354 EQ 2355
Score = 55.8 bits (133), Expect = 1e-07
Identities = 42/146 (28%), Positives = 72/146 (49%), Gaps = 16/146 (10%)
Query: 339 EDEEYYSEDED-----QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEE------EM 387
++EE E+E+ + R R +K K F ++ E E EE EE E+
Sbjct: 2178 DEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDEL 2237
Query: 388 KKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
+K+E EEEEE +++EE EE EE E ++E E+E+G +K + +++ ++
Sbjct: 2238 EKQESLSSEEEEEREEEEEREE-----EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK 2292
Query: 448 YGEVEEEPLDEAQDDDLDELMEMEPT 473
+ EE E ++ +E+M E T
Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSEEET 2318
Score = 53.5 bits (127), Expect = 5e-07
Identities = 37/150 (24%), Positives = 74/150 (49%), Gaps = 16/150 (10%)
Query: 341 EEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEM------KEKEEEEMKKEEEMKKK---- 390
EE +E+E + AR+H D + ++E+ + ++ +E K+ ++ K+K
Sbjct: 2157 EEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQ 2216
Query: 391 ------EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGT 444
EE EE E + + E++E + EEE ++EE E+E+ ++ E +++ G
Sbjct: 2217 VDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 445 EETYGEVEEEPLDEAQDDDLDELMEMEPTF 474
E+ + EEE + ++ +E+ E E F
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKEEVQEKEEVF 2306
Score = 46.2 bits (108), Expect = 8e-05
Identities = 26/99 (26%), Positives = 58/99 (58%), Gaps = 3/99 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
+EE E EE E E++E ++ + K+++K ++E+ E++EE M +EE +E+E
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKK---KEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQK 433
EEE ++++ + E+ K E++ + +++ + G ++
Sbjct: 2327 EEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365
Score = 43.5 bits (101), Expect = 5e-04
Identities = 34/138 (24%), Positives = 68/138 (49%), Gaps = 18/138 (13%)
Query: 332 SPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK- 390
SP EE ++++ +E ++ + L SK +E + K+EEE+ EEE+ ++
Sbjct: 1504 SPEEEMLQEDKKLKWEEWKQVWENMLSSK---------SKEQQYKDEEEVTLEEEVSREG 1554
Query: 391 EEKEEEEEEEMKQKEEEEE---IRNKNEEEGESKDEED-----EDEDGGQKPEGEPQQDP 442
EEKE++ EE + +EE + I K + + +E+ E+E Q+ Q++
Sbjct: 1555 EEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEER 1614
Query: 443 GTEETYGEVEEEPLDEAQ 460
+ Y ++ ++ + AQ
Sbjct: 1615 KLAQAYVKITQDDREMAQ 1632
Score = 43.1 bits (100), Expect = 7e-04
Identities = 34/143 (23%), Positives = 74/143 (51%), Gaps = 12/143 (8%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAF------QQEMKEKEEEEMKKEEEMK 388
++ +++E +++E++ A+ R ++++RK +A+ +EM + E + +KEE +
Sbjct: 1586 KKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLA 1645
Query: 389 KKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETY 448
++ EK +E E++ QK + + + E +++EE + GG+ E + EE
Sbjct: 1646 QRGEKLSQEAEKLAQKRK----KLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEEL- 1700
Query: 449 GEVEEEPLDEAQDDDLDELMEME 471
E+ LD + + EL E+E
Sbjct: 1701 -PQREQNLDWQEKELAQELEELE 1722
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/106 (24%), Positives = 58/106 (54%), Gaps = 6/106 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E++ +E+ + ++E + AR HR ++ ++KR Q+E K +EEE +EE + +E+
Sbjct: 1558 EQQVTEEQRHIQEEHKWARIHRKRARAEKKRA---QEERKLAQEEEKLAQEERQLAQEER 1614
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
+ + +K +++ E+ + EG+ +E+ G+K E ++
Sbjct: 1615 KLAQAYVKITQDDREMA---QAEGKFAQKEETLAQRGEKLSQEAEK 1657
Score = 39.3 bits (90), Expect = 0.010
Identities = 25/92 (27%), Positives = 52/92 (56%), Gaps = 6/92 (6%)
Query: 361 DQRKRMRAFQQEMKEK---EEEEMKKEEEMKKKEEKEEEEEEEMKQKEEE---EEIRNKN 414
+ RK +A+++E +++ EEE++ + E EE+ +E++++K +E + E + +
Sbjct: 1473 ETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSK 1532
Query: 415 EEEGESKDEEDEDEDGGQKPEGEPQQDPGTEE 446
+E + KDEE+ + EGE ++ TEE
Sbjct: 1533 SKEQQYKDEEEVTLEEEVSREGEEKEQQVTEE 1564
Score = 39.3 bits (90), Expect = 0.010
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 9/138 (6%)
Query: 303 ECVEIERKVRVPKPIPLPGVRNIIFPFAPS-PNEEES---EDEEYYSEDEDQEARRHRLH 358
E V E + K L V+NI+ P E++ +++E E E+ E L
Sbjct: 1670 EKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELS 1729
Query: 359 SKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEG 418
K++ Q+E K EE++ EEE ++E+ EEE K +EEE + + E+
Sbjct: 1730 WKEEELN----QEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLA 1785
Query: 419 ESKDEEDEDEDG-GQKPE 435
+ K++ E+E+ G+K E
Sbjct: 1786 QHKEKMPEEEERLGRKRE 1803
Score = 38.9 bits (89), Expect = 0.013
Identities = 39/143 (27%), Positives = 72/143 (50%), Gaps = 11/143 (7%)
Query: 338 SEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE--- 394
SE ++DE + AR+ R + R RM +++M E+E + +K E+ +E+E
Sbjct: 2126 SEKRSELTKDEKKLARKQRKLANKMR-RMINKEEKMTEEESKLARKHSEVILDDEEEGGI 2184
Query: 395 EEEE-----EEMKQKEEEEEIRNKNEEEGESK-DEEDEDEDGGQKPEGEPQQDPGTEETY 448
EEEE + +K +E + +K +E+ S+ DE + +E ++ E + E
Sbjct: 2185 EEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLS 2244
Query: 449 GEVEEEPLDEAQDDDLDELMEME 471
E EEE +E ++ + +E+ E E
Sbjct: 2245 SEEEEER-EEEEEREEEEVREEE 2266
Score = 38.1 bits (87), Expect = 0.022
Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE S EE +++E + + ++++ A+Q+E +EE ++ +EEE+ +EKE
Sbjct: 1726 EELSWKEEELNQEEGKLVEEKKKLAEEEEAL--AWQREKLSEEETKLAQEEELLI-QEKE 1782
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESK 421
+ + + K EEEE + K E+ E K
Sbjct: 1783 KLAQHKEKMPEEEERLGRKREQLIEKK 1809
Score = 38.1 bits (87), Expect = 0.022
Identities = 48/207 (23%), Positives = 89/207 (42%), Gaps = 30/207 (14%)
Query: 273 QNQFLKGLSEFFRKELLWSTEMADLDELILECVEIERKVR--VPKPIPLPGVRNIIFPFA 330
Q + K + +K S E A L++++ ++ R R + I + ++ +F
Sbjct: 2049 QRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKE 2108
Query: 331 PSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK 390
+ E+S+ + ++ D +R L +KD++K R K+ + K M K
Sbjct: 2109 RRLSIEQSKLD---IKEWDFSEKRSEL-TKDEKKLAR--------KQRKLANKMRRMINK 2156
Query: 391 EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEE-----------DEDEDGGQKPE---G 436
EEK EEE ++ +K E+ +EEEG ++EE ++ G KP+
Sbjct: 2157 EEKMTEEESKLARK--HSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFS 2214
Query: 437 EPQQDPGTEETYGEVEEEPLDEAQDDD 463
+ +EE + E E LDE + +
Sbjct: 2215 SQVDEVESEEHFSEEMESLLDELEKQE 2241
Score = 37.4 bits (85), Expect = 0.037
Identities = 29/128 (22%), Positives = 61/128 (47%), Gaps = 7/128 (5%)
Query: 337 ESEDEEYYSEDE---DQEARRHRLHSKDQ-RKRMRAFQQEMKEKEEEEMKKEEEMKKKEE 392
+S++++Y E+E ++E R + Q + R Q+E K + E K+ +E
Sbjct: 1532 KSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQE 1591
Query: 393 KEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
+ + +EE K +EE ++ + + ++ + +D+ + EG+ Q EET +
Sbjct: 1592 ERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ---KEETLAQRG 1648
Query: 453 EEPLDEAQ 460
E+ EA+
Sbjct: 1649 EKLSQEAE 1656
Score = 36.2 bits (82), Expect = 0.083
Identities = 21/95 (22%), Positives = 49/95 (51%), Gaps = 19/95 (20%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQE---MKEKE-------------- 377
EEE E+++ E+E+++ ++ ++ +++ F+++ M E+E
Sbjct: 2272 EEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESC 2331
Query: 378 --EEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEI 410
EEE+ +E+E+ KKE++ + +E+ K E +
Sbjct: 2332 SLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366
Score = 33.5 bits (75), Expect = 0.54
Identities = 25/95 (26%), Positives = 52/95 (54%), Gaps = 7/95 (7%)
Query: 334 NEEES---EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEE----EEMKKEEE 386
N+EE E+++ +E+E+ A + S+++ K + + ++EKE+ +E EEE
Sbjct: 1736 NQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEE 1795
Query: 387 MKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESK 421
+ ++E+ E++MK ++ E N EE ++K
Sbjct: 1796 ERLGRKREQLIEKKMKLAQKRERWINSMEELTKNK 1830
Score = 33.1 bits (74), Expect = 0.70
Identities = 32/140 (22%), Positives = 67/140 (47%), Gaps = 8/140 (5%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
+ E ++ E +++ E+ A+R S++ K + ++++ +K E+ ++EE++ KK K
Sbjct: 1627 DREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQK-RKKLAKKWEKVAREEEKLAKKGGK 1685
Query: 394 EEEEE-------EEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEE 446
E + EE+ Q+E+ + + K + + E D +E ++ E ++ EE
Sbjct: 1686 LAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEE 1745
Query: 447 TYGEVEEEPLDEAQDDDLDE 466
EEE Q + L E
Sbjct: 1746 KKKLAEEEEALAWQREKLSE 1765
Score = 32.0 bits (71), Expect = 1.6
Identities = 24/88 (27%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
Query: 339 EDEEYYSEDEDQEARRHRL-HSKDQ----RKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
E E+ E+ + RL HSK Q + ++ F + + + EE+ +++E + KK+EK
Sbjct: 1849 EKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEK 1908
Query: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESK 421
E E+++ Q E+ + K E+ + K
Sbjct: 1909 LAETEKKLVQ--VEDSLAKKQEKLAQEK 1934
Score = 30.4 bits (67), Expect = 4.6
Identities = 27/144 (18%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRK------RMRAFQQEMKEKEEEEMKKEEEMK 388
E+ S++ E ++ + A++ ++++ K ++ + + +K EE ++E+ +
Sbjct: 1649 EKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLD 1708
Query: 389 KKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETY 448
+E++ +E EE++ EE + + + E K E++ + ++ Q++ +EE
Sbjct: 1709 WQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEET 1768
Query: 449 GEVEEEPLDEAQDDDLDELMEMEP 472
+EE L + + L + E P
Sbjct: 1769 KLAQEEELLIQEKEKLAQHKEKMP 1792
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 67.0 bits (162), Expect = 4e-11
Identities = 33/76 (43%), Positives = 54/76 (71%)
Query: 378 EEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGE 437
+EE ++EEE +++EE+EEEEEE+ +++EE+EE + EEE E + EE+ +E+ G+ E E
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Query: 438 PQQDPGTEETYGEVEE 453
++D EE EVE+
Sbjct: 947 EEEDEEEEEELEEVED 962
Score = 66.2 bits (160), Expect = 7e-11
Identities = 53/180 (29%), Positives = 85/180 (47%), Gaps = 43/180 (23%)
Query: 332 SPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKE 391
S +EEE E+EE E+E++E +++ + ++E +E+E EE +EEE + +E
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944
Query: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDE---------------DEDGGQKPEG 436
E+EEE+EEE ++ EE E++ E G + E +E + +PE
Sbjct: 945 EEEEEDEEEEEELEEVEDL-----EFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEP 999
Query: 437 EPQ-------QDPGTEE----------------TYGEVEEEPLDEAQDDDLDELMEMEPT 473
EP+ ++PGTEE + GEVE E A EL+E EP+
Sbjct: 1000 EPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPS 1059
Score = 65.1 bits (157), Expect = 2e-10
Identities = 36/89 (40%), Positives = 56/89 (62%), Gaps = 9/89 (10%)
Query: 373 MKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQ 432
+ +EEE ++EEE +++EE+EEEEE+ +++E+EEE + EEE E +EE E+E+G
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942
Query: 433 KPEGEPQQDPGTEETYGEVEEEPLDEAQD 461
+ E EE E EEE L+E +D
Sbjct: 943 EEE---------EEEEDEEEEEELEEVED 962
Score = 60.8 bits (146), Expect = 3e-09
Identities = 37/96 (38%), Positives = 59/96 (61%), Gaps = 8/96 (8%)
Query: 378 EEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGE 437
EE++ EE+EEEEEEE +++EEEE EEE ++EEDE+E ++ E E
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEE------EEEDFEEEEEDEEEYFEEEEEEE 928
Query: 438 PQQDPGTEETYGEV--EEEPLDEAQDDDLDELMEME 471
+ + EE GE+ EEE DE ++++L+E+ ++E
Sbjct: 929 EEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964
Score = 48.9 bits (115), Expect = 1e-05
Identities = 50/195 (25%), Positives = 76/195 (38%), Gaps = 67/195 (34%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMK------ 388
EEE EDEE Y E+E++E +++ + ++E E+EEEE+++ E+++
Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGG 970
Query: 389 ----------------------KKEEKEEEEEEEMKQKEEE---EEIRNKN--------- 414
K + E E E + + EE EE R +
Sbjct: 971 EVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEA 1030
Query: 415 -------EEEGES-----------KDE--------EDEDEDGGQKPEGEPQQDPGTEETY 448
E EGES ++E E+E EDG K + P + P EE
Sbjct: 1031 LPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQ-PPPETPAEEEME 1089
Query: 449 GEVEEEPLDEAQDDD 463
E E E L E + DD
Sbjct: 1090 TETEAEALQEKEQDD 1104
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/108 (31%), Positives = 52/108 (48%), Gaps = 12/108 (11%)
Query: 401 MKQKEEEEEIRNKNEEEGESKDEEDED-----EDGGQKPEGEPQQDPGTEETYGEVEEEP 455
+ +EEEE + EEE E ++EE+ED ED + E E +++ EE + E E E
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942
Query: 456 LDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENFLGASPPIIQP 503
+E +++D +E E+E T+G E GA PP P
Sbjct: 943 EEEEEEEDEEEEEELEEV-----EDLEFGTAGGEVEE--GAPPPPTLP 983
Score = 39.7 bits (91), Expect = 0.008
Identities = 28/87 (32%), Positives = 33/87 (37%), Gaps = 22/87 (25%)
Query: 114 PDGPADPPLLPIPPPPALPPPASKE------------PPPQPPLAPLER----------P 151
P G PP+ P PP A PP +KE PPP PP P+ P
Sbjct: 803 PSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVP 862
Query: 152 EIEPFSGDPVYLAEFLMQLETFIADHE 178
E P G P L E L + +D E
Sbjct: 863 EGTPGGGGPPALEEDLTVININSSDEE 889
Score = 37.4 bits (85), Expect = 0.037
Identities = 25/64 (39%), Positives = 32/64 (50%), Gaps = 10/64 (15%)
Query: 100 SDDLLINVIQDRSTPDGPADPPLLPIPPPPALPPPASKEPPP--QPPLAPLERPEIEPFS 157
SDD ++ V P+G PPL P PP A PPP + PP PP+ E PE P +
Sbjct: 784 SDDSVVIV------PEGL--PPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAA 835
Query: 158 GDPV 161
P+
Sbjct: 836 PGPL 839
Score = 33.9 bits (76), Expect = 0.41
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 1/43 (2%)
Query: 117 PADPPLLPIPPPPALPPPASKEPPPQPP-LAPLERPEIEPFSG 158
P P L P PPP PP EP P+P L +E P E G
Sbjct: 977 PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERG 1019
Score = 29.6 bits (65), Expect = 7.8
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 114 PDGPADPPLLPIPPPPALPPPASKEPPPQPP 144
P GP P P+PPP A P + PP PP
Sbjct: 640 PMGPTCPTPAPVPPPEA--PSPFRAPPFHPP 668
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 66.2 bits (160), Expect = 7e-11
Identities = 39/140 (27%), Positives = 83/140 (59%), Gaps = 15/140 (10%)
Query: 334 NEEESEDEEY-YSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEE 392
++E+ D+++ + +E+++ RRH L++K + +Q++ ++EEEE+++EE K++ +
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 393 KEEEE--EEEMKQKEEEEEIRNKNEE----------EGESKDEEDEDEDGGQKPEGEPQQ 440
++E + EEE Q+EEE+ +R + E+ + K ++ E++ G++PE +Q
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984
Query: 441 DPGTEETYGEVEEEPLDEAQ 460
+ E+ Y E EE +E Q
Sbjct: 985 E--REKKYREEEELQQEEEQ 1002
Score = 65.1 bits (157), Expect = 2e-10
Identities = 43/142 (30%), Positives = 79/142 (55%), Gaps = 12/142 (8%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EEE + EE E++E RR + + RK ++E++++EE+ +++E E ++++E+E
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRK-----EEELQQEEEQLLREEPEKRRRQERE 1107
Query: 395 EE--EEEEMKQKE-----EEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
+ EEEE++Q+E EE E R + E E + ++EE+ ++ Q EP++ E
Sbjct: 1108 RQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Query: 448 YGEVEEEPLDEAQDDDLDELME 469
EEE L + ++ L E E
Sbjct: 1168 RQYREEEELQQEEEQLLREEQE 1189
Score = 64.7 bits (156), Expect = 2e-10
Identities = 38/118 (32%), Positives = 67/118 (56%), Gaps = 9/118 (7%)
Query: 331 PSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK 390
P E E+EE + E QE RR R + Q++R+R QQ +++EEE +++EE +++
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQ 324
Query: 391 EEKEEEEEEEMKQ-----KEEEEEIRNKNEEEGESKDE----EDEDEDGGQKPEGEPQ 439
+E+ E++EE +Q +EE E + + E+E E +++ E E+E Q+ E Q
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Score = 64.7 bits (156), Expect = 2e-10
Identities = 53/228 (23%), Positives = 104/228 (45%), Gaps = 27/228 (11%)
Query: 335 EEESEDEEYYSEDE---DQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKE 391
EEE + SE + +QE RR +L +++ KR+ ++E + K E+E ++++ +K++E
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE 583
Query: 392 EKEE-----EEEEEMKQKEEEEEIRNKNEEEGES---KDEEDEDEDGGQKPEGEPQQDPG 443
E+ + E+EE ++Q+ + EE+ +EE K EE E+E Q + E Q++
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR 643
Query: 444 TEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENFLGASPPIIQP 503
++ E +E + ++ +E +E H + + E
Sbjct: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ----------- 692
Query: 504 SRRRNQNRVP-----LLEGLPGTNSPFYSSPQLIRRTGRLGQRQVRRR 546
+R R ++R+P L S YS P+ R +++ +RR
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRR 740
Score = 64.3 bits (155), Expect = 3e-10
Identities = 42/131 (32%), Positives = 68/131 (51%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395
EE DEE E E RR K Q++R R + +E+E+E K+E ++K+EEK +
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 396 EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEP 455
EEE + +++ +EEE + + E E + E E+E Q+ E Q EE E +EE
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 456 LDEAQDDDLDE 466
++ + + E
Sbjct: 322 REQQERREQQE 332
Score = 62.0 bits (149), Expect = 1e-09
Identities = 43/142 (30%), Positives = 76/142 (53%), Gaps = 12/142 (8%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EEE + EE E++E RR + + RK+ E++++EE+ +++E E ++ +E+E
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKK-----DELQQEEEQLLREEREKRRLQERE 1047
Query: 395 EE--EEEEMKQKE-----EEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
+ EEEE++Q+E EE E R + E E + + EE+ ++ Q EP++ E
Sbjct: 1048 RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE 1107
Query: 448 YGEVEEEPLDEAQDDDLDELME 469
EEE L + ++ L E E
Sbjct: 1108 RQCREEEELQQEEEQLLREERE 1129
Score = 61.6 bits (148), Expect = 2e-09
Identities = 40/130 (30%), Positives = 71/130 (54%), Gaps = 4/130 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQE---MKEKEEEEMKKEEEMKKKE 391
EE+ + EE E++E RR + + RK + Q+E + E+ E+ ++E E K +E
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Query: 392 EKE-EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGE 450
E+E ++EEE++ ++E E+ R + E + KDE ++E+ + E E ++ E Y E
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052
Query: 451 VEEEPLDEAQ 460
EE +E Q
Sbjct: 1053 EEELQQEEEQ 1062
Score = 60.1 bits (144), Expect = 5e-09
Identities = 34/135 (25%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEE-- 392
E+E E E E Q R +L + Q +R + ++E + + E+++++E++++++++
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 393 -KEEEEEEEMKQKEEEEEIRNKNEEEG-----ESKDEEDEDEDGGQKPEGEPQQDPGTEE 446
++EEE E K ++E E R K E+E + ++E + E +K + + Q+ E
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 447 TYGEVEEEPLDEAQD 461
+ ++EEE E Q+
Sbjct: 487 RWLKLEEEERREQQE 501
Score = 58.9 bits (141), Expect = 1e-08
Identities = 41/138 (29%), Positives = 74/138 (53%), Gaps = 19/138 (13%)
Query: 340 DEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE--- 396
+ +Y +DE Q+ L +++R++ R ++E + +EEEE+++EEE EE+E
Sbjct: 1017 ERQYRKKDELQQEEEQLL--REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 397 -------EEEEMKQKE-----EEEEIRNKNEEEGESKDEED--EDEDGGQKPEGEPQQDP 442
+EEE++Q+E EE E R + E E + ++EE+ ++E+ + E E ++
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 443 GTEETYGEVEEEPLDEAQ 460
E Y E EE +E Q
Sbjct: 1135 ELERQYREEEEVQQEEEQ 1152
Score = 58.5 bits (140), Expect = 2e-08
Identities = 37/153 (24%), Positives = 83/153 (54%), Gaps = 16/153 (10%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EEE ++++ E +Q +R + +D KR ++ +E+ ++++K+++E +++E
Sbjct: 430 EEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWL 489
Query: 395 EEEEEEMKQKEE--EEEIRNKNEEEGESK-DEEDEDEDGGQKPEGEPQ----QDPGTEET 447
+ EEEE ++++E E+++R + EE E + ++E+E Q+ E Q Q+ E+
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Query: 448 YGEVEEEPLDE---------AQDDDLDELMEME 471
EE+ L++ Q++ D+L++ E
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Score = 57.8 bits (138), Expect = 3e-08
Identities = 34/137 (24%), Positives = 71/137 (51%), Gaps = 7/137 (5%)
Query: 337 ESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKE--KEEEEMKKEEEMKKKEEKE 394
E +D + E+E + +R + K++ K Q +E +EEE+++K E + + E++
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
EEE+++ + + E++ +R K EEE + EE + Q+ E Q++ ++ E EE
Sbjct: 292 EEEQQQQRLRREQQ-LRRKQEEERREQQEERRE----QQERREQQEERREQQLRREQEER 346
Query: 455 PLDEAQDDDLDELMEME 471
+ + + +E E +
Sbjct: 347 REQQLRREQEEERREQQ 363
Score = 57.4 bits (137), Expect = 3e-08
Identities = 41/163 (25%), Positives = 79/163 (48%), Gaps = 16/163 (9%)
Query: 303 ECVEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESE----------DEEYYSEDEDQEA 352
E +E+ RK R K ++ +F EEE E +EE E+E Q
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQ-----EEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
Query: 353 RRHRLHSKDQRKRMRA-FQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIR 411
R + + RK R ++E +E+E+++ + E + + ++EEE E+ +++ E++E R
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Query: 412 NKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
+ EE E + +++E Q+ E +++ ++ E EEE
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Score = 55.8 bits (133), Expect = 1e-07
Identities = 42/174 (24%), Positives = 81/174 (46%), Gaps = 38/174 (21%)
Query: 333 PNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEE 392
P + ++ E +E++ + +++R++ R + E + +EEEE+++EEE +EE
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREE 1157
Query: 393 KEE----------EEEEEMKQKEE----EEEIRNKNEEEGESKDEE------------DE 426
E+ EEEE++Q+EE EE+ + + E E + ++EE DE
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Query: 427 DEDGGQKPEGEPQQDPGT-----------EETYGEVEEEPL-DEAQDDDLDELM 468
D+ K + EP+++ E + ++E+ L D DL L+
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLL 1271
Score = 55.5 bits (132), Expect = 1e-07
Identities = 38/139 (27%), Positives = 75/139 (53%), Gaps = 15/139 (10%)
Query: 339 EDEEYYSEDEDQEARRHRLHSK--DQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE 396
E+E+ E E+Q+ RR K ++ +++R ++E K +EE+ + +E+++K +EE+
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Query: 397 -----EEEEMKQKE------EEEEIRNKNEEEGESKDEEDED--EDGGQKPEGEPQQDPG 443
E+E+++++E EEE++R + EE+ + E D E+ + E E QQ
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
Query: 444 TEETYGEVEEEPLDEAQDD 462
E EEE L + +++
Sbjct: 1791 QESDRKFREEEQLRQEREE 1809
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/131 (30%), Positives = 70/131 (53%), Gaps = 17/131 (12%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE--- 395
E E Y ++E+ + +L ++ KR R ++E + +EEEE+++EEE +EE+E+
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQ-ERERQCREEEELQQEEEQLLREEREKRRR 1133
Query: 396 -------EEEEEMKQKE-----EEEEIRNKNEEEGESKDEED-EDEDGGQKPEGEPQQDP 442
EEEE++Q+E EE E R + E E + ++EE+ + E+ E + ++
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 443 GTEETYGEVEE 453
E Y E EE
Sbjct: 1194 ERERQYREEEE 1204
Score = 53.9 bits (128), Expect = 4e-07
Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 10/140 (7%)
Query: 331 PSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKK- 389
P+ E+ ++++ E+E++ R R + Q + + ++E ++EEE++ +EE K+
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
Query: 390 ---------KEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
K++K +++EE++ +E E+ R + E++ ++E ++E+ + E E ++
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 441 DPGTEETYGEVEEEPLDEAQ 460
E Y + +E +E Q
Sbjct: 1013 RQEWERQYRKKDELQQEEEQ 1032
Score = 52.4 bits (124), Expect = 1e-06
Identities = 34/134 (25%), Positives = 67/134 (50%), Gaps = 8/134 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKR----MRAFQQEMKE----KEEEEMKKEEE 386
+EE ++ E+ ++E R+ L S++Q +R +R QQE +E +EEEE + E+
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQR 671
Query: 387 MKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEE 446
+K++ E+E E+E ++++E+ R K+ E E + K P++ G
Sbjct: 672 LKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR 731
Query: 447 TYGEVEEEPLDEAQ 460
+ E+ E++
Sbjct: 732 RQEQEEKRRRRESE 745
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/143 (26%), Positives = 72/143 (50%), Gaps = 24/143 (16%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEM----------- 387
E E Y +D+ + + +L ++ KR R ++E K +EEEE+++EEE
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQ-EREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 388 -------KKKEEKEEEEEEEMKQKEE-----EEEIRNKNEEEGESKDEEDEDEDGGQKPE 435
+KK+E ++EEE+ ++++ E E E + + EEE + ++E+ E+ +
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Query: 436 GEPQQDPGTEETYGEVEEEPLDE 458
E ++ EE + EE+ L E
Sbjct: 1074 QELERQYRKEEELQQEEEQLLRE 1096
Score = 51.6 bits (122), Expect = 2e-06
Identities = 27/86 (31%), Positives = 53/86 (61%), Gaps = 4/86 (4%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEE 398
E+E+ E+++Q R+ R + R + QE +EE+E+ +EEE K+++E+E +
Sbjct: 1824 EEEQLQLEEQEQRLRQER--DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881
Query: 399 EEMKQKEEEEEIRNKNEEEGESKDEE 424
EE +++++EE R++ + GE K +E
Sbjct: 1882 EEHIRRQQKEEQRHR--QVGEIKSQE 1905
Score = 50.8 bits (120), Expect = 3e-06
Identities = 38/148 (25%), Positives = 75/148 (50%), Gaps = 6/148 (4%)
Query: 333 PNEEESEDEEYYSEDEDQEARRH-RLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKE 391
P E E+ D D++ R +L + + +++R +++ K +EEE+ + +E ++K
Sbjct: 1650 PQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Query: 392 EKEEEE--EEEMKQK-EEEEEIRNKNEEEGESKDEEDED--EDGGQKPEGEPQQDPGTEE 446
+EE++ +E+++K EEE++R + E+E + E E+ +PE E QQ E
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 447 TYGEVEEEPLDEAQDDDLDELMEMEPTF 474
EEE L + +++ E + F
Sbjct: 1770 DRKFREEEQLRQEREEQQLRSQESDRKF 1797
Score = 50.4 bits (119), Expect = 4e-06
Identities = 36/140 (25%), Positives = 72/140 (51%), Gaps = 8/140 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMK-EKEEEEMKKEEEMKKKEE- 392
++E E E + + E++E R + + Q +R + ++E + +++EEE + ++ ++ +++
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 393 -KEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
+E+EE E K EEE+ + E K E++E D K E E +Q E
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE----- 593
Query: 452 EEEPLDEAQDDDLDELMEME 471
+EE L++ + E +E E
Sbjct: 594 QEERLEQRLKREEVERLEQE 613
Score = 49.7 bits (117), Expect = 7e-06
Identities = 31/130 (23%), Positives = 70/130 (53%), Gaps = 8/130 (6%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEE 398
E+E+ E E+Q+ R +D++ R+ + +E+E + M+ E++++++E +++ +
Sbjct: 1559 EEEQLRQEREEQQLSRQE---RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615
Query: 399 EEMKQKEEEEEIRNKNEEEGESKDEED----EDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
E ++ E+E++ + EE+ + E D E+E ++ E E Q + + E EE+
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE-EEQ 1674
Query: 455 PLDEAQDDDL 464
L E ++ L
Sbjct: 1675 LLQEGEEQQL 1684
Score = 49.3 bits (116), Expect = 9e-06
Identities = 32/156 (20%), Positives = 78/156 (50%), Gaps = 18/156 (11%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E++ E E E QE RR + ++Q +R +++ +E+EE ++E+++++++E+E
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEER----REQQLRREQEEERREQQLRREQEEE 371
Query: 395 EEE-----EEEMKQKEE---------EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
E E++++++++ E+++R + + E + ++ Q+ E ++
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 441 DPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVH 476
+ ++ E E+ L Q++ D L E T H
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Score = 49.3 bits (116), Expect = 9e-06
Identities = 30/124 (24%), Positives = 66/124 (53%), Gaps = 7/124 (5%)
Query: 335 EEESEDEEY-YSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMK---KEEEMKKK 390
EE+ D + + +E E R RL ++ + R Q +E+++ E + +EEE +++
Sbjct: 761 EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR 820
Query: 391 EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGE 450
+ E E+E++ EEEE+++ + + ++E+ ED ++ E ++D ++ +
Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD---QKWRWQ 877
Query: 451 VEEE 454
+EEE
Sbjct: 878 LEEE 881
Score = 49.3 bits (116), Expect = 9e-06
Identities = 30/125 (24%), Positives = 69/125 (55%), Gaps = 4/125 (3%)
Query: 339 EDEEYYSEDED--QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE 396
E E + E+E QE + +L +++ +++ +Q E+EE++++++E +K E+E+
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQL 1779
Query: 397 EEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPL 456
+E +Q+ +E K EE + + E +E + Q+ +G+ + + E+ E +E+ L
Sbjct: 1780 RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE--EEQLQLEEQEQRL 1837
Query: 457 DEAQD 461
+ +D
Sbjct: 1838 RQERD 1842
Score = 48.9 bits (115), Expect = 1e-05
Identities = 31/145 (21%), Positives = 69/145 (47%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395
E+S+ + S+ + Q + +++R R Q++ EEE++++EE+ + K +
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Query: 396 EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEP 455
+EE+ +EE EE R + E + + ++EE ++ ++P ++D E +E+
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Query: 456 LDEAQDDDLDELMEMEPTFVHASSQ 480
+++ E E F+ Q
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQ 1398
Score = 48.9 bits (115), Expect = 1e-05
Identities = 35/167 (20%), Positives = 79/167 (47%), Gaps = 39/167 (23%)
Query: 336 EESEDEEYYSED-------EDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEE-------- 380
+E E+++ + ++ E+Q+ RR K + + +R+ + E K EEE+
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530
Query: 381 ---MKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEED------------ 425
+++E++++++E ++ ++ ++ EEE++R + EE+ S+ E D
Sbjct: 1531 RKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590
Query: 426 --------EDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDL 464
EDE ++ EG+ Q + + E +E+ L E ++ L
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE-DEQLLQEREEQQL 1636
Score = 48.5 bits (114), Expect = 2e-05
Identities = 36/153 (23%), Positives = 74/153 (48%), Gaps = 28/153 (18%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAF---QQEMKEKEE------------- 378
++ E E +E E+Q ++ RL +D+++R +QE +E+EE
Sbjct: 139 QKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKG 198
Query: 379 ---EEMKKEEEMKKKE----EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGG 431
EE EE+++++E ++ EE++ +++E ++ + + EE+ K E ++
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 432 QKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDL 464
+ E EPQ+ +E EEE L + + +L
Sbjct: 259 KLQEEEPQRQRELQE-----EEEQLRKLERQEL 286
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/140 (22%), Positives = 75/140 (53%), Gaps = 6/140 (4%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395
E+ ++ D+++E R L +++ +R + ++E + + E+E ++E+ +K+ +E+EE
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR-QEEEE 526
Query: 396 EEEEEMKQKE----EEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
++ ++ ++ E+EE R + + E K E E + K E E ++D + E
Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE-EER 585
Query: 452 EEEPLDEAQDDDLDELMEME 471
++ L Q++ L++ ++ E
Sbjct: 586 RQQRLKREQEERLEQRLKRE 605
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/116 (25%), Positives = 60/116 (51%), Gaps = 3/116 (2%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEE 398
E+E+ E E+Q RR K + + +R +Q K EEE+ + +E +E K +EE
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQE---RERKFLKEE 1396
Query: 399 EEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
++++ +E E+++R + + ++++ ++ +K E QQ E +EEE
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Score = 48.1 bits (113), Expect = 2e-05
Identities = 29/115 (25%), Positives = 63/115 (54%), Gaps = 4/115 (3%)
Query: 349 DQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEE 408
+Q+ RR + ++Q + R Q+ +E+ E+ +K+E+E ++ K EEE E +Q+ ++
Sbjct: 416 EQQLRREQQLRREQEEE-RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQ 474
Query: 409 EIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDD 463
+++ EEE + + E+E+ ++ E QQ +E E E+ L ++++
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE---ERREQRLKRQEEEE 526
Score = 47.4 bits (111), Expect = 4e-05
Identities = 35/138 (25%), Positives = 73/138 (52%), Gaps = 19/138 (13%)
Query: 340 DEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE--- 396
+EE +E +EA+R S+++++ +R ++E + ++E + K EE + +E+EE+
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 397 --------EEEEMKQKEE-----EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPG 443
EEE++ +E+ EEE R + +E E K ++E + Q+ E + +QD
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQER-ERKFLKEEQQLRCQEREQQLRQD-- 1411
Query: 444 TEETYGEVEEEPLDEAQD 461
+ + E E++ + +D
Sbjct: 1412 RDRKFREEEQQLSRQERD 1429
Score = 47.0 bits (110), Expect = 5e-05
Identities = 33/144 (22%), Positives = 71/144 (49%), Gaps = 14/144 (9%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEE---MKKEEEMKKKEE 392
E+ E E +E R + H +++R +Q +K ++EE +K+EEE ++ E+
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERR------EQRLKREQEERRDWLKREEETERHEQ 469
Query: 393 KEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
+ +++ + Q+EE E K EEE + +E ++ ++ E +Q +E ++
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 453 -----EEPLDEAQDDDLDELMEME 471
E+ L Q++ ++L++ E
Sbjct: 530 QRLRSEQQLRREQEERREQLLKRE 553
Score = 47.0 bits (110), Expect = 5e-05
Identities = 33/127 (25%), Positives = 68/127 (53%), Gaps = 14/127 (11%)
Query: 347 DEDQEARRHRLHSKDQRKRMRAFQQEMKEK--EEEEMKKEEEMKKKEEKEEE----EEEE 400
+E+Q+ RR K ++ + +QE++ K EEE++++E E ++ +E EEE+
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754
Query: 401 MKQKEEEEEIR-----NKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEP 455
++ + EE+++R K EE + + E +E + Q+ + + +++ E+ E EE+
Sbjct: 1755 LRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE---EQLRQEREEQQ 1811
Query: 456 LDEAQDD 462
L Q D
Sbjct: 1812 LRPQQRD 1818
Score = 46.6 bits (109), Expect = 6e-05
Identities = 35/153 (22%), Positives = 74/153 (48%), Gaps = 13/153 (8%)
Query: 342 EYYSEDEDQEARRHRLHSK--------DQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
E D +QE RR + + ++ ++ A +++ K +EE+++ +EE +K+ +
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 394 EEE----EEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYG 449
E + EEE++ Q+ EE+ +R + E + + ++EE ++ G+K E Q+ E
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLR-RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Query: 450 EVEEEPLDEAQDDDLDELMEMEPTFVHASSQTS 482
++EE Q+ + + + F Q S
Sbjct: 1392 FLKEEQQLRCQEREQQLRQDRDRKFREEEQQLS 1424
Score = 46.6 bits (109), Expect = 6e-05
Identities = 34/150 (22%), Positives = 74/150 (49%), Gaps = 15/150 (10%)
Query: 329 FAPSPNEEESEDEEYYSEDEDQEARRHRLHSK---DQRKRMRAFQQEMKEKE-------E 378
F + ++ E E+Q+ RR L K +++ R Q++++ +E E
Sbjct: 1693 FREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE 1752
Query: 379 EEMK--KEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEG 436
E+++ +EE+ +++E++ + EE + ++E EE + +++E EE++ ++ +
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Query: 437 EPQQDPGT---EETYGEVEEEPLDEAQDDD 463
PQQ G EE ++EE+ Q+ D
Sbjct: 1813 RPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Score = 45.8 bits (107), Expect = 1e-04
Identities = 31/143 (21%), Positives = 69/143 (48%), Gaps = 13/143 (9%)
Query: 334 NEEESEDEEYYSEDEDQEARRHR---------LHSKDQRKRMRAFQQEMKEKEEEEMKKE 384
+EEE ++E E+++Q R + L S+ ++ + + + K++ + +++
Sbjct: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
Query: 385 EEMKKKEEKE---EEEEEEMKQKEEEEEIRNKN-EEEGESKDEEDEDEDGGQKPEGEPQQ 440
EE +++ E E +EEE +Q++EEE+ R+ + + E K E + P E ++
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Query: 441 DPGTEETYGEVEEEPLDEAQDDD 463
E + E+ L E ++ +
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKE 818
Score = 45.4 bits (106), Expect = 1e-04
Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 16/152 (10%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKK---- 389
+E ++ + YS QE +R R +++R+R + Q +E+ ++EEE ++
Sbjct: 710 SEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTW 769
Query: 390 ---KEEKEEEEEEEMK-----QKEEEEEIRNKNEEEGESK---DEEDEDEDGGQKPEGEP 438
EEK E + + +++ E ++R + ++ E + +EE++++ Q+ E E
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
Query: 439 Q-QDPGTEETYGEVEEEPLDEAQDDDLDELME 469
+ Q EE E + ++D L E E
Sbjct: 830 ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Score = 45.4 bits (106), Expect = 1e-04
Identities = 30/131 (22%), Positives = 66/131 (50%), Gaps = 6/131 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEK--EEEEMKKEEEMKKKEE 392
E D + Y + + E R +D + R R QQ+++ E++E +E+E ++ ++
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQL---EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQ 1288
Query: 393 KEEE-EEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
++ EEE ++EE++E + ++ + E K E+ + ++ + ++ E+ E
Sbjct: 1289 RDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQER 1348
Query: 452 EEEPLDEAQDD 462
EE+PL + D
Sbjct: 1349 EEQPLRRQERD 1359
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/128 (22%), Positives = 63/128 (49%), Gaps = 8/128 (6%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRM--RAFQQEMKEKEEEEMKKEEEMKKKE 391
+EE+ E + E QE R RL +++ +R+ R ++ +E+ E+E+ +EE+ + +E
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695
Query: 392 EKEEEEEEEMKQKEEEEEIRNK------NEEEGESKDEEDEDEDGGQKPEGEPQQDPGTE 445
+ + Q E E + R ++EG+ + +E E++ ++ E + Q++
Sbjct: 696 RIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAH 755
Query: 446 ETYGEVEE 453
E E+
Sbjct: 756 RQQQEEEQ 763
Score = 45.1 bits (105), Expect = 2e-04
Identities = 42/192 (21%), Positives = 82/192 (42%), Gaps = 22/192 (11%)
Query: 335 EEESEDEEYYSEDEDQEARRHR----------LHSKDQRKRMRAFQQEMKEK----EEEE 380
E + ++ + E+E++E RR + L ++Q +R QQ +E+ E++E
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Query: 381 MKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDE-EDEDEDGGQKPEGEPQ 439
++ +E ++ ++ + EEE K++ + +E+ + + E+E+ Q+ E E +
Sbjct: 862 RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR 921
Query: 440 QDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENFLGASPP 499
+ E Y EEE L + ++ L E E E LG
Sbjct: 922 RRQEQERQYR--EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE--- 976
Query: 500 IIQPSRRRNQNR 511
+P +RR Q R
Sbjct: 977 --EPEKRRRQER 986
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/150 (26%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 335 EEESEDEEYYSE--DEDQEARRHRLHSK----DQRKRMRAFQQEMKEKEEEEMKKEEEMK 388
EEE +E + +E+Q RR K +Q+ R + +Q++++ + + ++EE+
Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQL 1423
Query: 389 KKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDED--EDGGQKPEGEPQQDPGTEE 446
++E++ + EE +Q +E R EEE + + E E+ E E QQ E
Sbjct: 1424 SRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQER 1483
Query: 447 TYGEVEEEPLDEAQDDDL----DELMEMEP 472
+EEE Q+ D EL EP
Sbjct: 1484 DRKFLEEEQQLRRQERDRKFREQELRSQEP 1513
Score = 44.7 bits (104), Expect = 2e-04
Identities = 49/209 (23%), Positives = 91/209 (43%), Gaps = 6/209 (2%)
Query: 251 LGSYADAFQFLAQFLSWD--DCRLQNQFLKGLSEFFRKELLWSTEMADLDELILECVEIE 308
L S D + Q++S D L + LK L E +L +LILE ++++
Sbjct: 5 LRSICDITEIFNQYVSHDCDGAALTKKDLKNLLEREFGAVLRRPHDPKTVDLILELLDLD 64
Query: 309 RKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRA 368
RV L + + + + DEE + + +E+ L + Q + R
Sbjct: 65 SNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGKESL---LQDRRQEEDQRR 121
Query: 369 FQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGES-KDEEDED 427
F+ ++ EEE ++ + ++++E+E E EE +K+E E R++ + E + ++
Sbjct: 122 FEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQ 181
Query: 428 EDGGQKPEGEPQQDPGTEETYGEVEEEPL 456
E ++ E E Q ET +EE L
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQL 210
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/127 (24%), Positives = 67/127 (52%), Gaps = 5/127 (3%)
Query: 350 QEARRHRLHSKDQRKRMRAFQQEMKEKEE---EEMKKEEEMKKKEEKEEEEEEEMKQKEE 406
+E R +L ++++++R + F E +EKE+ + ++E+E++ EE+E+ + E Q+ +
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 407 EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQ--DDDL 464
EEE + ++E E+ D+ + E E ++ T ++E+ E Q ++
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 465 DELMEME 471
+EL E
Sbjct: 911 EELQREE 917
Score = 44.3 bits (103), Expect = 3e-04
Identities = 26/106 (24%), Positives = 65/106 (61%), Gaps = 10/106 (9%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQE---MKEKEEEEMKKEEEMKKKEEKEE 395
E E + EDE Q+ RR + +++R R F+++ ++E+EE+++ ++E ++ K
Sbjct: 1592 EQERKFMEDE-QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE----RDRKFL 1646
Query: 396 EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQD 441
EEE +++++E E+++R ++ + + ++EE ++G ++ ++D
Sbjct: 1647 EEEPQLRRQEREQQLR--HDRDRKFREEEQLLQEGEEQQLRRQERD 1690
Score = 43.9 bits (102), Expect = 4e-04
Identities = 27/155 (17%), Positives = 78/155 (50%), Gaps = 22/155 (14%)
Query: 339 EDEEYYSEDEDQEARRH----RLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E+E+ E E+Q+ RR + ++Q ++ R QQ ++ + + ++EE+++++ E++
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 395 E-----------EEEEEMKQKEEEEEIRNKNEEEGESKDE-------EDEDEDGGQKPEG 436
+ EEE+++ +E+E+ +R + + + ++++ E+++ Q+ E
Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ 1870
Query: 437 EPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME 471
+ +Q+ + + + +E + + E+ E
Sbjct: 1871 KRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 43.5 bits (101), Expect = 5e-04
Identities = 36/159 (22%), Positives = 72/159 (45%), Gaps = 20/159 (12%)
Query: 333 PNEEESEDEEYY--------SEDEDQEARRHRLHSKDQRKRMRAFQQE---MKEKEEEEM 381
P EE+ E EE S++E Q R R + +++ R F++E ++E+EE+ +
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353
Query: 382 KKEEEMKKKEEKEEE---------EEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQ 432
+++E +K E+E EEE+ +++E E K E++ ++ E +
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413
Query: 433 KPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME 471
+ E +Q +E + EE + + + +E E
Sbjct: 1414 RKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Score = 43.5 bits (101), Expect = 5e-04
Identities = 29/112 (25%), Positives = 59/112 (52%), Gaps = 15/112 (13%)
Query: 339 EDEEYYSEDEDQEARRH--RLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE 396
E E+ +D D++ R +L +++ ++ R +Q+++ +E E EEE + ++E+ +
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462
Query: 397 --EEEEMKQKEEEEEIRNK-------NEEEGESKDEED----EDEDGGQKPE 435
EEE++ Q+ EE+++ + EE+ + E D E E Q+PE
Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/123 (24%), Positives = 66/123 (53%), Gaps = 14/123 (11%)
Query: 339 EDEEYYSEDEDQEARRHR---LHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395
E+++ ++ Q+ R+ R ++Q ++ R QQ +++ + + + EE+ +++E+E
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQER 1595
Query: 396 ---EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
E+E++++++E ++++R +E + K EDE E E QQ E +E
Sbjct: 1596 KFMEDEQQLRRQEGQQQLR----QERDRKFREDEQ----LLQEREEQQLHRQERDRKFLE 1647
Query: 453 EEP 455
EEP
Sbjct: 1648 EEP 1650
Score = 42.7 bits (99), Expect = 9e-04
Identities = 32/124 (25%), Positives = 66/124 (53%), Gaps = 12/124 (9%)
Query: 339 EDEEYYSEDEDQEARRHR-----LHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
EDE+ E E+Q+ R L + Q +R QQ +++ + ++E+ +++ EE+
Sbjct: 1623 EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQ 1682
Query: 394 E-EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
+ +E + K +EEE+++R +E E K ++E + Q+ E + +++ E+ E E
Sbjct: 1683 QLRRQERDRKFREEEQQLR---RQERERKFLQEEQQLRRQELERKFREE---EQLRQETE 1736
Query: 453 EEPL 456
+E L
Sbjct: 1737 QEQL 1740
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/117 (23%), Positives = 65/117 (55%), Gaps = 12/117 (10%)
Query: 349 DQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE----EEEEMKQK 404
+Q+ RR + ++Q+ R R ++E E++ E+ ++E+ +K+++E+ + EEE + +
Sbjct: 410 EQQLRREQQLRREQQLR-REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
Query: 405 EEEEEIRNKNEEEGESKD-----EEDEDEDGGQKPEGE--PQQDPGTEETYGEVEEE 454
+E + + K ++E E ++ EE+E + ++ E + +Q+ E+ EEE
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Score = 42.0 bits (97), Expect = 0.002
Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 39/172 (22%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKD--------QRKRMRAFQQEMKEKE-EEEMKKEEEMKK 389
+ +E +D QE + R +D QR+R + +QE + E EE+ +K+E +++
Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ 163
Query: 390 KEEKEEEEE-----EEMKQKEE---------------------EEEIRNKNEEEGESKDE 423
++ + +EE +E +++EE EE++R + E K
Sbjct: 164 RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGR 223
Query: 424 EDEDEDGGQKPEGEPQQDPGTE----ETYGEVEEEPLDEAQDDDLDELMEME 471
E++ + ++ + Q++ E ET EEE L E + EL E E
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
Score = 42.0 bits (97), Expect = 0.002
Identities = 27/126 (21%), Positives = 61/126 (48%), Gaps = 18/126 (14%)
Query: 336 EESEDEEYYSEDEDQEARRH-RLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK---- 390
+E E+++ S++ D++ R +L + + +++R Q++ K + EEE + EE +++
Sbjct: 1781 QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE 1840
Query: 391 -------------EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGE 437
+EK EE+E+ Q+EE++ + + + E + E+ + GE
Sbjct: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGE 1900
Query: 438 PQQDPG 443
+ G
Sbjct: 1901 IKSQEG 1906
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/152 (23%), Positives = 67/152 (44%), Gaps = 23/152 (15%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEE-- 392
E E E E +E+QE R R+ S R+ +Q +++ + + K +K+E
Sbjct: 675 EHEEERREQELAEEEQEQARERIKS-----RIPKWQWQLESEADARQSKVYSRPRKQEGQ 729
Query: 393 KEEEEEEEMKQK-------EEEEEIRNKNEEEGESKD------EEDEDEDGGQKPEGEPQ 439
+ +E+EE +++ +EEE + +EE + +D E++ E G Q+ P
Sbjct: 730 RRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP- 788
Query: 440 QDPGTEETYGEVEEEPLDEAQDDDLDELMEME 471
P E+ ++ E + + L E E E
Sbjct: 789 --PLREQRERQLRAEERQQREQRFLPEEEEKE 818
Score = 41.6 bits (96), Expect = 0.002
Identities = 44/201 (21%), Positives = 88/201 (43%), Gaps = 35/201 (17%)
Query: 298 DELILECVEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDED---QEARR 354
+E L C E E+++R R+ F + D ++ E++ QE R
Sbjct: 1395 EEQQLRCQEREQQLRQD--------RDRKFREEEQQLSRQERDRKFREEEQQVRRQERER 1446
Query: 355 HRLHSKDQ--RKRMRAFQQE---MKEKEEEEMKKEEEMKK-KEEKEEEEEEEMKQKEEEE 408
L + Q ++R R F++E ++E+EE+++ ++E +K EE+++ +E +K E+
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
Query: 409 EIRNKNEEEGESKDEED------------------EDEDGGQKPEGEPQQDPGTEETYGE 450
E+R++ E ++E+ E G Q+ + ++ E+ E
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
Query: 451 VEEEPLDEAQDDDLDELMEME 471
EE+ L + D L E +
Sbjct: 1567 REEQQLSRQERDRKFRLEEQK 1587
Score = 40.8 bits (94), Expect = 0.003
Identities = 27/129 (20%), Positives = 64/129 (49%), Gaps = 14/129 (10%)
Query: 337 ESEDEEYYSEDE-DQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMK----------KEE 385
+ D ++ E++ QE +L S++ ++ R +Q +E+EE++++ +EE
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 386 EMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTE 445
+++ +E+++ +E +Q EE+ + + E ++ E+E QK E ++ E
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE---QKRRQERERKLREE 1883
Query: 446 ETYGEVEEE 454
+ +EE
Sbjct: 1884 HIRRQQKEE 1892
Score = 40.4 bits (93), Expect = 0.004
Identities = 33/148 (22%), Positives = 75/148 (50%), Gaps = 14/148 (9%)
Query: 336 EESEDEEYYSEDEDQEAR--RHRLHSKDQRKRMRAFQQEMKEKE-EEEMKKEEEMKKKEE 392
+E E+++ ++ D++ R ++ ++Q ++ +Q+++ +E ++++++E + K +E+
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRED 1624
Query: 393 K----EEEEEEEMKQK------EEEEEIRNKNEEEGESKDEEDEDEDGGQ-KPEGEPQQD 441
+ E EE++ +Q+ EEE ++R + E+ D + + + Q EGE QQ
Sbjct: 1625 EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684
Query: 442 PGTEETYGEVEEEPLDEAQDDDLDELME 469
E EEE Q+ + L E
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQE 1712
Score = 40.0 bits (92), Expect = 0.006
Identities = 24/113 (21%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Query: 361 DQRKRMRAFQQE--MKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEG 418
D+ KR R +E ++++ +EE ++ E + ++ +EE + ++++E+E + EE+
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQS 155
Query: 419 ESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME 471
E ++ ++ + + E Q+ E EEE L + + +E + E
Sbjct: 156 EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEE 208
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 65.5 bits (158), Expect = 1e-10
Identities = 46/145 (31%), Positives = 77/145 (53%), Gaps = 12/145 (8%)
Query: 335 EEESEDEEYYSEDEDQEA--RRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKK--- 389
EE+ D+E D+++ + RL K++R R + + +EK EE K +E+ KK
Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD 551
Query: 390 KEEKEEEEEE----EMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTE 445
+EEK EEE E K +EEEE +R + E+ E +++ E E+ + E + Q+ E
Sbjct: 552 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ---E 608
Query: 446 ETYGEVEEEPLDEAQDDDLDELMEM 470
E E EE+ ++ ++D + E EM
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEM 633
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/131 (28%), Positives = 81/131 (61%), Gaps = 3/131 (2%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
++EE EE + +++ R ++Q ++M+ +++M+E+EE+ ++EE+M+++EEK
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Query: 394 EEEEEEEMKQKEEEEEIRNKNEE--EGESKDEEDEDEDGGQKPEGEPQQDPGTE-ETYGE 450
E+EE+M ++EEE++++ + E E E K +E E++ Q+ + Q++ E E +
Sbjct: 611 MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQ 670
Query: 451 VEEEPLDEAQD 461
+EE + E ++
Sbjct: 671 GQEEKMREQEE 681
Score = 64.7 bits (156), Expect = 2e-10
Identities = 39/132 (29%), Positives = 78/132 (59%), Gaps = 3/132 (2%)
Query: 336 EESEDEEYYSEDEDQEAR-RHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE + +E + DQE + R +++ K+MR ++ M+E+EE+ ++EE+M+++EEK
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 395 EEEEEEMKQKEEE--EEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
E+EE+M+++EE+ E+ E+E E K +E E+ Q+ + + Q++ E+ E
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 657
Query: 453 EEPLDEAQDDDL 464
+E Q++ +
Sbjct: 658 QEEKMREQEEKM 669
Score = 63.9 bits (154), Expect = 4e-10
Identities = 41/139 (29%), Positives = 79/139 (56%), Gaps = 6/139 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE + E +E++ R ++Q ++MR +++M E+EE+ ++EE+M ++EEK
Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618
Query: 395 EEEEEEMKQKEEEEEIRNKNE--EEGESK--DEEDEDEDGGQKPEGEPQQDPGTEETYGE 450
E+EEE K +E+EE + + E +E E K ++E++ + +K + ++ G EE E
Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRE 678
Query: 451 VEEEPLDEAQDDDLDELME 469
EE+ + Q++ + E E
Sbjct: 679 QEEKM--QGQEEKMREQEE 695
Score = 63.9 bits (154), Expect = 4e-10
Identities = 36/148 (24%), Positives = 83/148 (56%), Gaps = 4/148 (2%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEE 398
++E+ + ++E+ + + +Q ++M+ +++M E+EE+ ++EE+M+++EEK + +E
Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Query: 399 EEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDE 458
E+M+++EE+ + + + E E K E++ GQ+ + Q+ E+ +G+ E +E
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQE----EKMWGQEEMREKEE 729
Query: 459 AQDDDLDELMEMEPTFVHASSQTSGPTS 486
D +++ E P S+ P S
Sbjct: 730 RIRDQKEKMQERLPEHEERCSEPCLPPS 757
Score = 62.0 bits (149), Expect = 1e-09
Identities = 39/138 (28%), Positives = 78/138 (56%), Gaps = 12/138 (8%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEK------EEEEMKKEEEMK 388
EE ++E +++++ RR ++Q K +R ++E++E+ EE+ ++EE+M
Sbjct: 261 EERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMW 320
Query: 389 KKEEKEEEEEEEMKQKEEE--EEIRNKNEEEGESKDEE----DEDEDGGQKPEGEPQQDP 442
++EEK E+EE+M ++EE E+ + E+E + +D+E ++DE +K E +Q+
Sbjct: 321 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 380
Query: 443 GTEETYGEVEEEPLDEAQ 460
E+ EEE + E +
Sbjct: 381 MWEQEEKMQEEERIRERE 398
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/126 (28%), Positives = 69/126 (54%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E+E + E + DQE R + + K R +QE ++EE+M++EE ++++E+K
Sbjct: 342 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKM 401
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
EEEE M+++EE+ + + +N E E K+ + + ++ E ++ EE E EE+
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 455 PLDEAQ 460
D+ +
Sbjct: 462 IRDQEE 467
Score = 60.8 bits (146), Expect = 3e-09
Identities = 39/137 (28%), Positives = 80/137 (58%), Gaps = 10/137 (7%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E++++++E + D++++ R + +RMR +++M+E+EE ++EE+M+++EEK
Sbjct: 539 EKKTQEQEKKTWDQEEKMR--------EEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGE--PQQDPGTEETYGEVE 452
E+EE+M ++EE+ + + + E E K E E+ED Q+ E Q++ E+ E
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Query: 453 EEPLDEAQDDDLDELME 469
+E Q++ + E E
Sbjct: 651 QEEKMREQEEKMREQEE 667
Score = 60.5 bits (145), Expect = 4e-09
Identities = 38/138 (27%), Positives = 79/138 (57%), Gaps = 11/138 (7%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ ++E +++++ R +Q K+MR +Q+M+++EE +++E +++KEE+
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 375
Query: 395 EEEEEEMKQKE---EEEEIRNK----NEEEGESKDEED----EDEDGGQKPEGEPQQDPG 443
E+E+ +Q+E EEE IR + EEE +++E+ ++E+ ++ E E QQ
Sbjct: 376 REQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 435
Query: 444 TEETYGEVEEEPLDEAQD 461
E+ E+E + E ++
Sbjct: 436 PEQKEKLWEQEKMQEQEE 453
Score = 60.1 bits (144), Expect = 5e-09
Identities = 36/124 (29%), Positives = 73/124 (58%), Gaps = 4/124 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE ++E ++++++ R +Q ++M+ +++M E+EE+ ++EEE K +E++E
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632
Query: 395 E--EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQD--PGTEETYGE 450
E+EE+M+++EE+ + + E E K E E++ GQ+ + Q++ G EE E
Sbjct: 633 MMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692
Query: 451 VEEE 454
EE+
Sbjct: 693 QEEK 696
Score = 58.9 bits (141), Expect = 1e-08
Identities = 39/131 (29%), Positives = 76/131 (58%), Gaps = 7/131 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE ++E E E++ R+ +++ K+MR ++ M+E+EE+ K+EE M ++EEKE
Sbjct: 372 EERMREQEKMWEQEEKMQEEERI--REREKKMREEEETMREQEEKMQKQEENMWEQEEKE 429
Query: 395 EEEEEEMKQKE---EEEEIRNKNEEEGESKDE-EDEDEDGGQ-KPEGEPQQDPGTEETYG 449
+++ +QKE E+E+++ + E+ E +++ D++E GQ K ++ E+
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 450 EVEEEPLDEAQ 460
E EE+ D+ Q
Sbjct: 490 EQEEKMRDQEQ 500
Score = 58.5 bits (140), Expect = 2e-08
Identities = 36/152 (23%), Positives = 74/152 (48%), Gaps = 40/152 (26%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ +++E +++++ R ++Q ++M+ +++M+E+EE+ +EE+M+++EEK
Sbjct: 638 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697
Query: 395 EEEEEEM------------------KQKEEEEEIRNKNEEEGESKDEEDE---------- 426
+EE+M + +E+EE IR++ E+ E E +E
Sbjct: 698 RGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPS 757
Query: 427 ------------DEDGGQKPEGEPQQDPGTEE 446
+ GG+ EG PQ +P +E
Sbjct: 758 KVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQE 789
Score = 57.8 bits (138), Expect = 3e-08
Identities = 42/137 (30%), Positives = 75/137 (54%), Gaps = 13/137 (9%)
Query: 334 NEEESEDEEYYSEDED--QEARRHRLHSKDQRKRMRAFQQEMKEKEEE-------EMKKE 384
+E E EE E + Q+ + R K Q + + + QE K +EEE +M++E
Sbjct: 513 DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
Query: 385 EE-MKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPG 443
EE M+++EEK +E+EE+M+++EE+ + + +E E K E E++ Q+ E + Q+
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ-- 630
Query: 444 TEETYGEVEEEPLDEAQ 460
EE E EE+ ++ +
Sbjct: 631 -EEMMWEQEEKMQEQEE 646
Score = 55.5 bits (132), Expect = 1e-07
Identities = 35/144 (24%), Positives = 83/144 (57%), Gaps = 7/144 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ +++E +++++ R Q +R+ +++M+E+E++ +EE M +++E+
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 395 EEEEEEMKQKEE--EEEIRNKNEE---EGESKDEEDEDEDGGQKPEGEPQQDPGTEETYG 449
E+EE M+++E+ E+E + + EE E E K E+E+ Q+ + + Q++ E+
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 428
Query: 450 EVEEEPLDEAQDD--DLDELMEME 471
E +++ L E ++ + +++ E E
Sbjct: 429 EWQQQRLPEQKEKLWEQEKMQEQE 452
Score = 54.3 bits (129), Expect = 3e-07
Identities = 44/195 (22%), Positives = 98/195 (50%), Gaps = 22/195 (11%)
Query: 295 ADLDELILECVEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARR 354
++ E+ L E++RK+ K + LP V+ EEE ++E ++++ R
Sbjct: 201 SEKSEIQLNVKELKRKLERAKFL-LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 259
Query: 355 HRLHSKDQRKRMRAFQQEMKEKE-------------EEEMKKEEEMKKKEEKEEEEEEEM 401
++Q +MR +++M+ +E E+E++++++++++EE+ +E+EE+M
Sbjct: 260 QEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM 319
Query: 402 -----KQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPL 456
K +E+EE++ + E E + + E E QK + ++ +E E EE
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQE---QKMRDQEERMWEQDERLREKEERMR 376
Query: 457 DEAQDDDLDELMEME 471
++ + + +E M+ E
Sbjct: 377 EQEKMWEQEEKMQEE 391
Score = 53.9 bits (128), Expect = 4e-07
Identities = 36/147 (24%), Positives = 78/147 (53%), Gaps = 13/147 (8%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK- 393
EE+ +E ++++E R ++Q+K +R +++M+E+EE+ ++EE+M+++EEK
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKK-LREQEEQMQEQEEKMWEQEEKMREQEEKM 333
Query: 394 --------EEEE---EEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDP 442
E+E+ E+E K +++EE + ++E E ++ E E ++ E +++
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER 393
Query: 443 GTEETYGEVEEEPLDEAQDDDLDELME 469
E EEE Q++ + + E
Sbjct: 394 IREREKKMREEEETMREQEEKMQKQEE 420
Score = 53.9 bits (128), Expect = 4e-07
Identities = 35/143 (24%), Positives = 76/143 (53%), Gaps = 6/143 (4%)
Query: 335 EEESEDEEYYSE-DEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
E+E E E E E ++ R ++Q ++M +++M+E+EE+ ++EE + ++E++
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 394 EEEEEEEMKQKEE-----EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETY 448
E+E++M+ +EE +E +R K E E + +++E ++ ++ EE
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
Query: 449 GEVEEEPLDEAQDDDLDELMEME 471
E+E + Q++++ E E E
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKE 429
Score = 53.5 bits (127), Expect = 5e-07
Identities = 32/132 (24%), Positives = 73/132 (55%), Gaps = 7/132 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKD-----QRKRMRAFQQEMKEKEEEEMKKEEEMKK 389
EE+ D+E E + R+ ++ ++ Q ++MR +Q+M ++EE +++E +++
Sbjct: 459 EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE 518
Query: 390 KEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYG 449
KEE+ E+++ +Q+E+ E + E+E ++ D+E++ + + E E + EE
Sbjct: 519 KEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM--REEEEMM 576
Query: 450 EVEEEPLDEAQD 461
+EE + E ++
Sbjct: 577 REQEEKMQEQEE 588
Score = 49.7 bits (117), Expect = 7e-06
Identities = 32/143 (22%), Positives = 76/143 (53%), Gaps = 8/143 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQR----KRMRAFQQEMKEKEEEEMKKEEEMKKK 390
E+ E EE E E++ + + ++++ ++MR + +M E+EE+ +E++M +
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 391 EEKEEEEEEEMKQKE----EEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEE 446
EE+ E++E +++KE E++++ + E+ E K +++++ + E +++ E
Sbjct: 506 EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRER 565
Query: 447 TYGEVEEEPLDEAQDDDLDELME 469
EEE + Q++ + E E
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEE 588
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/126 (26%), Positives = 65/126 (51%), Gaps = 9/126 (7%)
Query: 337 ESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK--- 393
ESE E ++ + + R + + Q+EM +EEE ++E++++K+EEK
Sbjct: 200 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 259
Query: 394 --EEEEEEEMKQKEEEEEIRNK----NEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
E E+E K +E+EE++R + E+E E +++E E + + E E Q E+
Sbjct: 260 QEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM 319
Query: 448 YGEVEE 453
+ + E+
Sbjct: 320 WEQEEK 325
Score = 48.5 bits (114), Expect = 2e-05
Identities = 31/131 (23%), Positives = 68/131 (51%), Gaps = 12/131 (9%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKE---------- 384
+EE EE + +++ R ++Q ++M+ ++ M E+EE+E +++
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 443
Query: 385 --EEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDP 442
E+M+++EEK E+EE+++ +EE K + + +++ED+ + +K + Q+
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503
Query: 443 GTEETYGEVEE 453
EE E +E
Sbjct: 504 DQEERMWEQDE 514
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/146 (23%), Positives = 73/146 (50%), Gaps = 14/146 (9%)
Query: 335 EEESEDEEYYSEDEDQEARRHRL---------HSKDQRKRMRAFQQEMKEKEEEEMKKEE 385
E+ + EE E E++E ++ RL K Q + + ++QE K +++EEM +E
Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 472
Query: 386 EMKKKEEKEEEEEEEM-----KQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
+ ++EK E+E++M K +++E+++ ++ E E + E E+ ++ + QQ
Sbjct: 473 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532
Query: 441 DPGTEETYGEVEEEPLDEAQDDDLDE 466
+ E E+E Q++ + E
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMRE 558
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/127 (25%), Positives = 66/127 (51%), Gaps = 5/127 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E+E E+ E +E R + Q K+M Q++M+E+E++ ++EE+M+ +E+K
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR-QEKMREQEDQMWEQEEKMRDQEQKM 502
Query: 395 -EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE 453
++EE E++E +R K E E K ++E ++ + + Q+ ++ EE
Sbjct: 503 WDQEERMW---EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
Query: 454 EPLDEAQ 460
E + E +
Sbjct: 560 ERMRERE 566
Score = 43.9 bits (102), Expect = 4e-04
Identities = 31/136 (22%), Positives = 70/136 (51%), Gaps = 3/136 (2%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEK--EEEEMKKEEE-MKKKEEKEE 395
E+E ++E + + + +++++ + E KEK E+E+M+++EE + ++EEK
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
Query: 396 EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEP 455
++EE Q+++ E+E + ++E++ D QK + ++ +E E EE
Sbjct: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM 523
Query: 456 LDEAQDDDLDELMEME 471
++ + +E M E
Sbjct: 524 REQKKMWQQEEKMREE 539
Score = 33.1 bits (74), Expect = 0.70
Identities = 30/138 (21%), Positives = 68/138 (49%), Gaps = 20/138 (14%)
Query: 351 EARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKE---EEMKKKEEK-------------- 393
E R+ + +++ +K+ Q++++ E E+ + + +E+K+K E+
Sbjct: 174 ELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 233
Query: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEP--QQDPGTEETYGEV 451
EE +E + +E+E++IR K EE+ ++E +++G + + E +Q+ E E+
Sbjct: 234 EEMWRQEEELREQEKKIR-KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL 292
Query: 452 EEEPLDEAQDDDLDELME 469
E+ + + L E E
Sbjct: 293 REQEKELREQKKLREQEE 310
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 65.1 bits (157), Expect = 2e-10
Identities = 49/231 (21%), Positives = 104/231 (45%), Gaps = 16/231 (6%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
N E + ++ + + ++ H H QR+R Q+E + + EE+ ++E E +K +EK
Sbjct: 365 NSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEK 424
Query: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE 453
E++ E Q EE R + E E E K ++ E++ ++ + + QQ+ ++ + ++
Sbjct: 425 EQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQ 484
Query: 454 EPLDEAQDDDLDELM--EMEPTFVHASSQTSGPTSGYHAENFLGASPPIIQPSRRRNQNR 511
+ + Q +L+ + +P + + + E + + +R Q
Sbjct: 485 Q--QQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWARE--------VEERTRMNKQQN 534
Query: 512 VPLLEGLPGTNSPFYSSPQLIRRTGRLGQRQVRRRPPVLFRLTPRQGGHRA 562
PL + PG+ P PQ G G + + PP+ + P++G H++
Sbjct: 535 SPLAKSKPGSTGPEPPIPQ--ASPGPPG--PLSQTPPMQRPVEPQEGPHKS 581
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 65.1 bits (157), Expect = 2e-10
Identities = 49/231 (21%), Positives = 104/231 (45%), Gaps = 16/231 (6%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
N E + ++ + + ++ H H QR+R Q+E + + EE+ ++E E +K +EK
Sbjct: 365 NSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEK 424
Query: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE 453
E++ E Q EE R + E E E K ++ E++ ++ + + QQ+ ++ + ++
Sbjct: 425 EQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQ 484
Query: 454 EPLDEAQDDDLDELM--EMEPTFVHASSQTSGPTSGYHAENFLGASPPIIQPSRRRNQNR 511
+ + Q +L+ + +P + + + E + + +R Q
Sbjct: 485 Q--QQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWARE--------VEERTRMNKQQN 534
Query: 512 VPLLEGLPGTNSPFYSSPQLIRRTGRLGQRQVRRRPPVLFRLTPRQGGHRA 562
PL + PG+ P PQ G G + + PP+ + P++G H++
Sbjct: 535 SPLAKSKPGSTGPEPPIPQ--ASPGPPG--PLSQTPPMQRPVEPQEGPHKS 581
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 65.1 bits (157), Expect = 2e-10
Identities = 49/231 (21%), Positives = 104/231 (45%), Gaps = 16/231 (6%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
N E + ++ + + ++ H H QR+R Q+E + + EE+ ++E E +K +EK
Sbjct: 365 NSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEK 424
Query: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE 453
E++ E Q EE R + E E E K ++ E++ ++ + + QQ+ ++ + ++
Sbjct: 425 EQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQ 484
Query: 454 EPLDEAQDDDLDELM--EMEPTFVHASSQTSGPTSGYHAENFLGASPPIIQPSRRRNQNR 511
+ + Q +L+ + +P + + + E + + +R Q
Sbjct: 485 Q--QQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWARE--------VEERTRMNKQQN 534
Query: 512 VPLLEGLPGTNSPFYSSPQLIRRTGRLGQRQVRRRPPVLFRLTPRQGGHRA 562
PL + PG+ P PQ G G + + PP+ + P++G H++
Sbjct: 535 SPLAKSKPGSTGPEPPIPQ--ASPGPPG--PLSQTPPMQRPVEPQEGPHKS 581
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 65.1 bits (157), Expect = 2e-10
Identities = 49/231 (21%), Positives = 104/231 (45%), Gaps = 16/231 (6%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
N E + ++ + + ++ H H QR+R Q+E + + EE+ ++E E +K +EK
Sbjct: 365 NSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEK 424
Query: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE 453
E++ E Q EE R + E E E K ++ E++ ++ + + QQ+ ++ + ++
Sbjct: 425 EQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQ 484
Query: 454 EPLDEAQDDDLDELM--EMEPTFVHASSQTSGPTSGYHAENFLGASPPIIQPSRRRNQNR 511
+ + Q +L+ + +P + + + E + + +R Q
Sbjct: 485 Q--QQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWARE--------VEERTRMNKQQN 534
Query: 512 VPLLEGLPGTNSPFYSSPQLIRRTGRLGQRQVRRRPPVLFRLTPRQGGHRA 562
PL + PG+ P PQ G G + + PP+ + P++G H++
Sbjct: 535 SPLAKSKPGSTGPEPPIPQ--ASPGPPG--PLSQTPPMQRPVEPQEGPHKS 581
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 64.3 bits (155), Expect = 3e-10
Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 20/171 (11%)
Query: 314 PKPIPLPGVRN-------IIFPFAPSPN----EEESE----DEEYYSEDEDQEARRHRLH 358
P+P P P + I FA P +EESE DE ED+DQ+ +R R+
Sbjct: 149 PEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVT 208
Query: 359 SKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEG 418
S+++ R ++ + K +KEEE +KEEK + K+ +++++ + + E
Sbjct: 209 SRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQT--KEPTPKQKLKEEPDREA 266
Query: 419 ESKDEEDEDEDGGQKPEGEPQQDP---GTEETYGEVEEEPLDEAQDDDLDE 466
+ + DEDEDG +K E + + P + E E E ++ D+ DE
Sbjct: 267 RAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE 317
Score = 41.2 bits (95), Expect = 0.003
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 24/143 (16%)
Query: 307 IERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRM 366
+ + RV +P+P A S E E+E +++E +R R +K+ +
Sbjct: 207 VTSRERVARPLPAEEPER-----AKSGTRTEKEEER-----DEKEEKRLRSQTKEPTPK- 255
Query: 367 RAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEE---------MKQKEEEEEIRNKNEEE 417
Q++KE+ + E + + + E+ +E++E++ K++ EE+E N +
Sbjct: 256 ----QKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQI 311
Query: 418 GESKDEEDEDEDGGQKPEGEPQQ 440
+ KDE++++E + EP +
Sbjct: 312 SDEKDEDEKEEKRRKTTPKEPTE 334
Score = 35.8 bits (81), Expect = 0.11
Identities = 34/140 (24%), Positives = 64/140 (45%), Gaps = 22/140 (15%)
Query: 331 PSPNEEESEDEEYYS-------EDED---QEARRHRLHSKDQRKRMRAFQQEMKEKEEEE 380
P+P ++ E+ + + EDED ++ ++HR KD + R +EKE E+
Sbjct: 252 PTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP-----EEKEPEK 306
Query: 381 MKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
+ + +K E+++EE+ + KE E+ + + SK + GQ +
Sbjct: 307 VNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLD----- 361
Query: 441 DPGTEETYGEVEEEPLDEAQ 460
DP + YG+ + +DE Q
Sbjct: 362 DPDLK--YGQHPPDAVDEPQ 379
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 64.3 bits (155), Expect = 3e-10
Identities = 43/140 (30%), Positives = 78/140 (55%), Gaps = 9/140 (6%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
++E E++E ++E R L K + +R+R +E K+EEE K++EE KKK+E E
Sbjct: 414 QKEQEEQERVEKEEQDRLEREELKRKAEEERLRL--EEEARKQEEERKRQEEEKKKQEGE 471
Query: 395 EEEE--EEMKQKEEEE-EIRNKNEEEGESKDEEDEDEDGGQKPEGE--PQQDPGTEETYG 449
E+ + EE K+K EEE ++ K E+E + K ++ ++ + E Q E+
Sbjct: 472 EKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIML 531
Query: 450 EVEEEPLDEAQDDDLDELME 469
++E+E L+ + +DE+M+
Sbjct: 532 QIEQERLERKK--RIDEIMK 549
Score = 55.1 bits (131), Expect = 2e-07
Identities = 33/101 (32%), Positives = 57/101 (56%), Gaps = 4/101 (3%)
Query: 374 KEKEEEEMKKEEEMKKKEEKEEE---EEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDG 430
+++ + ++KE+E +++ EKEE+ E EE+K+K EEE +R EE + ++E E+
Sbjct: 406 EKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLR-LEEEARKQEEERKRQEEE 464
Query: 431 GQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME 471
+K EGE ++ G E EE L E Q+ + E +E
Sbjct: 465 KKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIE 505
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 3/75 (4%)
Query: 340 DEEYYSEDEDQEARRHRLHSKDQR---KRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE 396
DE E +E R L +++Q+ K+ RA Q K+ EE K EE+ +++++K
Sbjct: 52 DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAA 111
Query: 397 EEEEMKQKEEEEEIR 411
EE+ KQK EEE R
Sbjct: 112 VEEKRKQKLREEEER 126
Score = 38.9 bits (89), Expect = 0.013
Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 333 PNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEE-----EMKKEEEM 387
PN E + DE Q + R +++ K + A +Q++ EK++ E + EE
Sbjct: 38 PNYRPQGMEGFLKSDERQRLAKER--REEREKCLAAREQQILEKQKRARLQYEKQMEERW 95
Query: 388 KKKEEKEEEEEEEMKQKEEEEEIRNKNEEE 417
+K EE+ + E+++ EE+ + + + EEE
Sbjct: 96 RKLEEQRQREDQKRAAVEEKRKQKLREEEE 125
Score = 36.2 bits (82), Expect = 0.083
Identities = 20/100 (20%), Positives = 48/100 (48%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E+ EE + E++ + + + Q K M Q+E E + E+ ++ +++++
Sbjct: 472 EKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIML 531
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKP 434
+ E+E +++K+ +EI + + + ED G +P
Sbjct: 532 QIEQERLERKKRIDEIMKRTRKSDVPPQVKKEDPKVGVQP 571
Score = 34.7 bits (78), Expect = 0.24
Identities = 19/77 (24%), Positives = 46/77 (59%), Gaps = 9/77 (11%)
Query: 361 DQRKRMRAFQQEMKEK-----EEEEMKKEEEMKKKEEKEEEEE----EEMKQKEEEEEIR 411
D+R+R+ ++E +EK E++ ++K++ + + EK+ EE EE +Q+E+++
Sbjct: 52 DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAA 111
Query: 412 NKNEEEGESKDEEDEDE 428
+ + + + ++EE+ E
Sbjct: 112 VEEKRKQKLREEEERLE 128
Score = 34.3 bits (77), Expect = 0.32
Identities = 27/113 (23%), Positives = 56/113 (49%), Gaps = 12/113 (10%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395
+ E+E+ E E++ + ++ KR + +KEK+E+E +++ ++K++E E
Sbjct: 459 KRQEEEKKKQEGEEKR------KAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAE 512
Query: 396 EEEEEMKQK---EEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQ---QDP 442
+ E+ ++ E E+ + +E E K DE +K + PQ +DP
Sbjct: 513 TKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVPPQVKKEDP 565
Score = 33.5 bits (75), Expect = 0.54
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 335 EEESEDEEYYSEDEDQ---EARRHRL-HSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK 390
E E E+ + E Q + +R RL + K +R R +++ + ++++ EE+ K+K
Sbjct: 60 ERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQK 119
Query: 391 EEKEEEEEEEMKQKEEE 407
+EEE E M ++ E
Sbjct: 120 LREEEERLEAMMRRSLE 136
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 63.9 bits (154), Expect = 4e-10
Identities = 38/132 (28%), Positives = 78/132 (59%), Gaps = 4/132 (3%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ ++E ++++++ RR ++Q K++R +QE K +E+EEM +E+E K E++
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR--EQEEKIREQEEMMQEQEEKMGEQEG 474
Query: 395 EEEEEEMKQKEEEEEIRNKNEE--EGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
+ E+E K +E+EE++R + E+ E E K E E++ Q+ + Q++ E+ E
Sbjct: 475 KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 534
Query: 453 EEPLDEAQDDDL 464
+E + Q++ +
Sbjct: 535 QEEKMQEQEEKM 546
Score = 62.8 bits (151), Expect = 8e-10
Identities = 41/137 (29%), Positives = 78/137 (56%), Gaps = 5/137 (3%)
Query: 335 EEESEDEEYYSEDE---DQEARRHRLHSK--DQRKRMRAFQQEMKEKEEEEMKKEEEMKK 389
EE+ ++EE E E +QEA+ R K +Q +++R ++ M+E+EE+ ++EE+M +
Sbjct: 363 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWE 422
Query: 390 KEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYG 449
+EE+ +E+EE+M+++EE+ + K E E K E E+ Q+ + Q+ E+
Sbjct: 423 QEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482
Query: 450 EVEEEPLDEAQDDDLDE 466
E+E Q++ + E
Sbjct: 483 MQEQEEKMRRQEEKIRE 499
Score = 60.5 bits (145), Expect = 4e-09
Identities = 37/138 (26%), Positives = 77/138 (55%), Gaps = 8/138 (5%)
Query: 337 ESEDEEYYSEDEDQEARRHRLHS-----KDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKE 391
+ ++E+ + ++E + R ++ ++Q ++MR ++ M EKEE+ ++EE M +KE
Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 343
Query: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
EK E EE+M ++E+ E K +EE + +++E E Q+ + Q++ E+
Sbjct: 344 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE---QEAKMWRQEEKIREQEEKIR 400
Query: 452 EEEPLDEAQDDDLDELME 469
E+E + + Q++ + E E
Sbjct: 401 EQEEMMQEQEEKMGEQEE 418
Score = 60.1 bits (144), Expect = 5e-09
Identities = 34/132 (25%), Positives = 74/132 (56%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EEE +++E ++++ R ++Q +++R ++ M+E+EE+ ++E +M ++E K
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
+E+EE+M+++EE+ + K E E K E E+ Q+ + Q++ E+ E+E
Sbjct: 484 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 543
Query: 455 PLDEAQDDDLDE 466
Q++ + E
Sbjct: 544 EKMRRQEEKMRE 555
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/141 (30%), Positives = 79/141 (56%), Gaps = 11/141 (7%)
Query: 335 EEESEDEEYYSEDED--QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEE--MKKK 390
EE+ ++E E E+ QE + R K Q + + ++QE K +E+EE +E+E M+++
Sbjct: 350 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ 409
Query: 391 EEKEEEEEEEMKQKEE-----EEEIRNKNEE--EGESKDEEDEDEDGGQKPEGEPQQDPG 443
EEK E+EE+M ++EE EE++R + E+ E E K E E++ Q+ + Q++
Sbjct: 410 EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 444 TEETYGEVEEEPLDEAQDDDL 464
E+ E+E + Q++ +
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKM 490
Score = 58.5 bits (140), Expect = 2e-08
Identities = 34/135 (25%), Positives = 78/135 (57%), Gaps = 3/135 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ +++E +++++ RR ++ ++MR Q+EM ++EE++++ EE ++EK
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRR-QEEMMWEKEEKIRELEEKMHEQEKI 359
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
E+EE+ +++E+ E + E+E + +E++ + +K + + EE GE EE+
Sbjct: 360 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 419
Query: 455 PLDEAQDDDLDELME 469
+ Q++++ E E
Sbjct: 420 MWE--QEEEMQEQEE 432
Score = 58.2 bits (139), Expect = 2e-08
Identities = 35/142 (24%), Positives = 82/142 (57%), Gaps = 7/142 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ ++E ++++ + +Q ++M ++EM+E+EE+ ++EE+++++E+K
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 395 EEEEEEMKQKEE--EEEIRNKNEEEG-----ESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
E+EE+++++EE +E+ E+EG E+K +E E++ Q+ + Q+ E+
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Query: 448 YGEVEEEPLDEAQDDDLDELME 469
E+E + + Q++ + E E
Sbjct: 509 EKIREQEEMMQEQEEKMWEQEE 530
Score = 56.2 bits (134), Expect = 8e-08
Identities = 42/135 (31%), Positives = 78/135 (57%), Gaps = 7/135 (5%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEE-MKKEEEMK-KKEEKEEE 396
E+E + ++ QE + R K Q + + +QE K +E+EE M+++EEM +KEEK
Sbjct: 275 ENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRR 334
Query: 397 EEEEMKQKEEE-EEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEP 455
+EE M +KEE+ E+ K E+ + +++E++ ++ + E E +Q+ +E +EE
Sbjct: 335 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE---QEAKMWRQEEK 391
Query: 456 LDEAQDDDLDELMEM 470
+ E Q++ + E EM
Sbjct: 392 IRE-QEEKIREQEEM 405
Score = 55.5 bits (132), Expect = 1e-07
Identities = 35/134 (26%), Positives = 76/134 (56%), Gaps = 4/134 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ ++E +++++ R ++Q ++M + +M E+E + ++EE+M+++EEK
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497
Query: 395 EEEEEEMKQKEEEEEIRNKNE--EEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
E+E+ K +E+EE+IR + E +E E K E E++ Q+ + + Q++ + E
Sbjct: 498 REQEK--KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 453 EEPLDEAQDDDLDE 466
+E Q++ + E
Sbjct: 556 QEVRLRQQEEKMQE 569
Score = 54.7 bits (130), Expect = 2e-07
Identities = 38/147 (25%), Positives = 80/147 (54%), Gaps = 11/147 (7%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKE----KEEEEMKKEEEMKKK 390
EE+ +E +++++ RR ++ +++R +++M E +E+EE ++EEE ++
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 374
Query: 391 EEKEEEEEEEMKQKEE---EEEIRNKNEE----EGESKDEEDEDEDGGQKPEGEPQQDPG 443
+EK +E+E +M ++EE E+E + + +E E E K E E++ Q+ E + Q++
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Query: 444 TEETYGEVEEEPLDEAQDDDLDELMEM 470
+ E+E Q++ + E EM
Sbjct: 435 RRQEEKIREQEKKIREQEEKIREQEEM 461
Score = 53.9 bits (128), Expect = 4e-07
Identities = 32/132 (24%), Positives = 75/132 (56%), Gaps = 1/132 (0%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E+E + E + +QE R + + + +++R Q++ +E+E + ++EE+++++EEK
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKI 399
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
E+EE M+++EE+ + + E E + +E E++ Q+ + Q+ E+ E+E
Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459
Query: 455 PLDEAQDDDLDE 466
+ + Q++ + E
Sbjct: 460 EMMQEQEEKMGE 471
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/176 (25%), Positives = 84/176 (47%), Gaps = 24/176 (13%)
Query: 295 ADLDELILECVEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARR 354
++ E+ L E++RK+ K ++ P E + +E S +A+
Sbjct: 223 SEKSEIQLNVKELKRKLERAK---------LLLPQQQLQAEADHLGKELQSVSAKLQAQ- 272
Query: 355 HRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE---EEEEEMKQKEE----- 406
+ + R+ Q+E ++EE++++ EE K +E+EE E+EE+M+++EE
Sbjct: 273 --VEENELWNRLNQQQEEKMWRQEEKIQEREE--KIQEQEEKIREQEEKMRRQEEMMWEK 328
Query: 407 EEEIRNKNEE--EGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQ 460
EE++R + E E E K E E++ Q+ E ++ EE E E+ EA+
Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Score = 37.7 bits (86), Expect = 0.029
Identities = 24/98 (24%), Positives = 57/98 (58%), Gaps = 12/98 (12%)
Query: 374 KEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQK 433
+++EE+ ++EE+++++EEK +E+EE+++ E+EE++R + E E +++ E+ +
Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIR--EQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 434 PEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME 471
E E E+EE+ ++ + + +E + E
Sbjct: 342 KE----------EKIRELEEKMHEQEKIREQEEKRQEE 369
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 63.2 bits (152), Expect = 6e-10
Identities = 37/137 (27%), Positives = 81/137 (59%), Gaps = 3/137 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ ++E +++++ R +Q K+MR +Q+M+++EE +++E +++KEE+
Sbjct: 354 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 413
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
E+E+ +Q E+ E + E+E +++D+E++ ++ + E E + EET E EE+
Sbjct: 414 REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE-EEETMREQEEK 472
Query: 455 PLDEAQDDDLDELMEME 471
+ Q++++ E E E
Sbjct: 473 M--QKQEENMWEQEEKE 487
Score = 62.8 bits (151), Expect = 8e-10
Identities = 40/138 (28%), Positives = 79/138 (57%), Gaps = 2/138 (1%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQ-RKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
E++ D+E E + QE + +++ R+ R ++E K +EEEEM +E+E K +E++
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Query: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEE 453
E+ +E+E K E+EE+++ + E+ E +++ E E+ + + P+Q E E+
Sbjct: 617 EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 676
Query: 454 EPLDEAQDDDLDELMEME 471
E + E Q++ + E +ME
Sbjct: 677 EKMQE-QEEKIWEQEKME 693
Score = 62.0 bits (149), Expect = 1e-09
Identities = 36/130 (27%), Positives = 75/130 (57%), Gaps = 3/130 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEK---EEEEMKKEEEMKKKE 391
+E+ ++E +++++ R DQ +RM QE ++K +EE+M++EE M+++E
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRERE 595
Query: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
+K EEEE M+++EE+ + + + +E E K E E++ Q+ + Q++ E+
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 452 EEEPLDEAQD 461
E++ L E ++
Sbjct: 656 EQQRLPEQKE 665
Score = 62.0 bits (149), Expect = 1e-09
Identities = 51/201 (25%), Positives = 99/201 (49%), Gaps = 45/201 (22%)
Query: 267 WDDCRLQNQFLKGLSEFFRKELLWSTE-------MADLDELILECVEIERKVRVPKPIPL 319
W+ RL Q KE LW E M + +E I E ++E+K +
Sbjct: 655 WEQQRLPEQ----------KEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQ------- 697
Query: 320 PGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEE 379
E+++ D+E E+E R ++ +++ + MR +++M+E+EE+
Sbjct: 698 -------------EQEKKTWDQEKMREEESMREREKKM--REEEEMMREQEEKMQEQEEK 742
Query: 380 EMKKEEEMKKKEEKEEEEEEEMKQK----EEEEEI--RNKNEEEGESKDEEDEDEDGGQK 433
++EEEM ++EEK E+EE+M ++ E++E++ K +E+ + ++E++ D +K
Sbjct: 743 MQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802
Query: 434 PEGEPQQDPGTEETYGEVEEE 454
G+ ++ G EE EE+
Sbjct: 803 MRGQEEKMRGQEEKMRGQEEK 823
Score = 61.2 bits (147), Expect = 2e-09
Identities = 43/150 (28%), Positives = 79/150 (52%), Gaps = 15/150 (10%)
Query: 337 ESEDEEYYSEDE--DQEAR----RHRLHSKDQRKRMRAFQQEMKEKEEE-------EMKK 383
E ED+ + E++ DQE + R+ K Q + + + QE K +EEE +M++
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 384 EEEMKKKEEKEEEEEEEMKQKEEEE--EIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQD 441
EEEM +++E++ +E+EE Q++EE+ E K +E+ E E++E ++ E Q+
Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 442 PGTEETYGEVEEEPLDEAQDDDLDELMEME 471
P +E E E+ E + +++ E E
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Score = 60.8 bits (146), Expect = 3e-09
Identities = 38/150 (25%), Positives = 84/150 (56%), Gaps = 14/150 (9%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE ++E +++++ R ++Q K +R ++E++E++E ++EE+M+++EEK
Sbjct: 299 EERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELR-EQEEQMQEQEEKM 357
Query: 395 EEEEEEMKQKEEE---------EEIRNKNEEEGESKDEE----DEDEDGGQKPEGEPQQD 441
E+EE+M+++EE+ E+ + E+E + +D+E ++DE +K E +Q+
Sbjct: 358 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 417
Query: 442 PGTEETYGEVEEEPLDEAQDDDLDELMEME 471
E+ EE+ + E + D+ +M+
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Score = 60.8 bits (146), Expect = 3e-09
Identities = 37/137 (27%), Positives = 78/137 (56%), Gaps = 10/137 (7%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEE-----EEMKKEEEMKK 389
EE ++E +++Q+ R +Q +R+R ++ M+E+E+ E+M++E++M++
Sbjct: 375 EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434
Query: 390 KEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDE-----DEDGGQKPEGEPQQDPGT 444
+E+K ++EE+M+++E E K EE E+ E++E +E+ ++ E E QQ
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494
Query: 445 EETYGEVEEEPLDEAQD 461
E+ E+E + E ++
Sbjct: 495 EQKEKLWEQEKMQEQEE 511
Score = 60.1 bits (144), Expect = 5e-09
Identities = 35/140 (25%), Positives = 83/140 (59%), Gaps = 2/140 (1%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
++EE EE + +++ R ++Q ++M+ +++M+E+EE+ ++EE+M+++EEK
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 394 EEEEEEEMKQKEEE--EEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
E+EE+M ++EE+ E+ R ++E + E+ ++++ Q+ E + + E+ E
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ 699
Query: 452 EEEPLDEAQDDDLDELMEME 471
E++ D+ + + + + E E
Sbjct: 700 EKKTWDQEKMREEESMRERE 719
Score = 59.7 bits (143), Expect = 7e-09
Identities = 39/141 (27%), Positives = 80/141 (56%), Gaps = 5/141 (3%)
Query: 336 EESEDEEYYSEDEDQEAR-RHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE + +E + DQE + + +++ K+MR ++ M+E+EE+ K+EE M ++EEKE
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 487
Query: 395 EEEEEEMKQKE---EEEEIRNKNEEEGESKDE-EDEDEDGGQKPEGEPQQDPGTEETYGE 450
+++ +QKE E+E+++ + E+ E +++ D++E GQ+ + Q+ +E
Sbjct: 488 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547
Query: 451 VEEEPLDEAQDDDLDELMEME 471
+EE + + + D+ ME
Sbjct: 548 EQEEKMRDQEQKMWDQEERME 568
Score = 59.7 bits (143), Expect = 7e-09
Identities = 34/135 (25%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395
E+ +++E E E++ + ++ K Q + + + QE +EE ++E++M+++EE
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 396 EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEP 455
E+EE+M +E+EE+++ + EE E +++ E E+ + + P+Q E E+E
Sbjct: 731 EQEEKM--QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788
Query: 456 LDEAQDDDLDELMEM 470
+ E ++ D+ +M
Sbjct: 789 IWEQEEKMRDQEEKM 803
Score = 58.5 bits (140), Expect = 2e-08
Identities = 32/137 (23%), Positives = 80/137 (58%), Gaps = 1/137 (0%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E+E E+ E+++ + ++DQ ++M+ ++ ++E+E++ ++EE M+++EEK
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEETMREQEEKM 473
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
+++EE M ++EE+E + + E+ E E+++ ++ +K + ++ EE +G+ ++
Sbjct: 474 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 533
Query: 455 PLDEAQDDDLDELMEME 471
E + D++ E E
Sbjct: 534 WRQEKMREQEDQMWEQE 550
Score = 55.8 bits (133), Expect = 1e-07
Identities = 34/137 (24%), Positives = 77/137 (56%), Gaps = 4/137 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
E+E E+ E +E R + Q K+M Q++M+E+E++ ++EE+M+ +E+K
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR-QEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
++EE M++K +E+E + ++EE ++E + + + E E ++ +E + +EE
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE---QEEKMQEQEE 617
Query: 455 PLDEAQDDDLDELMEME 471
+ E ++ ++ +M+
Sbjct: 618 KMQEQEEKMWEQEEKMQ 634
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/138 (26%), Positives = 76/138 (55%), Gaps = 13/138 (9%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRK------RMRAFQQEMKEKE------EEEMK 382
E++ D+E ++D+ R ++Q K +MR +++M+E+E EE+M+
Sbjct: 389 EQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMRE-EKKMQEQEKKTRDQEEKMQ 447
Query: 383 KEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDP 442
+EE ++++E+K EEEE M+++EE+ + + +N E E K+ + + ++ E ++
Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Query: 443 GTEETYGEVEEEPLDEAQ 460
EE E EE+ D+ +
Sbjct: 508 EQEEKIWEQEEKIRDQEE 525
Score = 52.8 bits (125), Expect = 9e-07
Identities = 33/132 (25%), Positives = 71/132 (53%), Gaps = 6/132 (4%)
Query: 335 EEESEDEEYYSE-DEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
E+E E E E E +E R ++Q ++M +++M+E+EE+ ++EE + ++E++
Sbjct: 325 EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 394 EEEEEEEMKQKEE-----EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETY 448
E+E++M+ +EE +E +R K E E + ++ E ++ + + Q+ ++
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 449 GEVEEEPLDEAQ 460
EEE + E +
Sbjct: 445 KMQEEERIRERE 456
Score = 52.8 bits (125), Expect = 9e-07
Identities = 32/131 (24%), Positives = 72/131 (54%), Gaps = 6/131 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ D+E E + R+ ++ ++Q +M +++M+++E++ +EE M+KK +++
Sbjct: 517 EEKIRDQEEMWGQEKKMWRQEKM--REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 395 E----EEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGE 450
E ++EE+M+++E E K EE E E++E ++ E ++ +E +
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634
Query: 451 VEEEPLDEAQD 461
+EE + E ++
Sbjct: 635 EQEEKMWEQEE 645
Score = 52.0 bits (123), Expect = 1e-06
Identities = 40/155 (25%), Positives = 76/155 (49%), Gaps = 21/155 (13%)
Query: 335 EEESEDEEYYSEDEDQEARRHRL---------HSKDQRKRMRAFQQEMKEKEEEEMKKEE 385
E+ + EE E E++E ++ RL K Q + + ++QE K +++EEM +E
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 386 EMKKKEEKEEEEEEEMKQKEE-----------EEEIRNKNEEEGESKDEEDEDEDGGQKP 434
+ ++EK E+E++M ++EE +EE K +E E K + E++ ++
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590
Query: 435 EGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELME 469
E ++ EE +EE + E Q++ + E E
Sbjct: 591 MREREKKMREEEEMMREQEEKMQE-QEEKMQEQEE 624
Score = 51.2 bits (121), Expect = 2e-06
Identities = 31/119 (26%), Positives = 65/119 (54%), Gaps = 4/119 (3%)
Query: 319 LPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEE 378
LP + ++ +E+ ++E D++++ R + Q ++MR +++M +EE
Sbjct: 770 LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEE 829
Query: 379 EEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEE----GESKDEEDEDEDGGQK 433
+ +EE+M +EEK +EE+M++K + +E + + +EE E K E E++ GQ+
Sbjct: 830 KMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/142 (24%), Positives = 77/142 (54%), Gaps = 7/142 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQR----KRMRAFQQEMKEKEEEEMKKEEEMKKK 390
E+ E EE E E++ + + ++++ ++MR + +M E+EE+ +E++M +
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 391 EEKEEEEEEEMKQKEEEEEIRNKNEE---EGESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
EE+ E++ +E ++K ++E + + EE E E K E+E+ Q+ + + Q++ E+
Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 623
Query: 448 YGEVEEEPLDEAQDDDLDELME 469
E+E + Q++ + E E
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEE 645
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/144 (24%), Positives = 76/144 (52%), Gaps = 8/144 (5%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEE----EMKKK 390
E+E + +E + ++QE + K Q + + ++QE K E+EE E+ E K+K
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK 666
Query: 391 EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEE----DEDEDGGQKPEGEPQQDPGTEE 446
+ E+ +E+ K +E+EE+I + + E +++++E D+++ ++ E ++ EE
Sbjct: 667 LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 447 TYGEVEEEPLDEAQDDDLDELMEM 470
+EE + E ++ ++ EM
Sbjct: 727 EMMREQEEKMQEQEEKMQEQEEEM 750
Score = 50.8 bits (120), Expect = 3e-06
Identities = 40/156 (25%), Positives = 84/156 (53%), Gaps = 19/156 (12%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQR--KRMRAFQQEMKEKEEEEMKKEEEMKKKEE 392
E+ E EE E E++ + RL + ++ + + +QE +++EE++ ++E+M+KK +
Sbjct: 638 EKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQ 697
Query: 393 KEEE---------EEEEMKQKE----EEEEIRNKNEE---EGESKDEEDEDEDGGQKPE- 435
++E+ EEE M+++E EEEE+ + EE E E K +E E+E Q+ +
Sbjct: 698 EQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKM 757
Query: 436 GEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME 471
E ++ ++ E +E+ + + + +++ E E
Sbjct: 758 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Score = 49.7 bits (117), Expect = 7e-06
Identities = 33/146 (22%), Positives = 76/146 (52%), Gaps = 9/146 (6%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEM------- 387
EE ++E ++++++ + +Q ++M+ +++M E+EE+ ++EE+M
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 388 KKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
++KE+ E E+ + ++K +E+E + +E+ E K +E E + Q+ E + E+
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKK 721
Query: 448 YGEVEE--EPLDEAQDDDLDELMEME 471
E EE +E + +++ E E
Sbjct: 722 MREEEEMMREQEEKMQEQEEKMQEQE 747
Score = 49.7 bits (117), Expect = 7e-06
Identities = 43/136 (31%), Positives = 70/136 (51%), Gaps = 16/136 (11%)
Query: 335 EEESEDEEYYSEDEDQEARRHRL---------HSKDQRKRMRAFQQEMKEKEEEEMK-KE 384
EE E EE E E++ + RL H K Q + Q+E +EE+M+ +E
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE 807
Query: 385 EEMKKKEEKEEEEEEEMKQKEE----EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
E+M+ +EEK +EE+M +EE +EE EE+ ++E+ E++ GQ+ + Q+
Sbjct: 808 EKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQE 867
Query: 441 DP--GTEETYGEVEEE 454
+ G EE E EE+
Sbjct: 868 EKMRGQEEKMREQEEK 883
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/141 (23%), Positives = 71/141 (50%), Gaps = 7/141 (4%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395
E+ E E + ++QE + K + + + ++QE + E+E+ +E+E K ++++E
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398
Query: 396 --EEEEEMKQKEEEEEIRNKNEEEGESKDEE---DEDEDGGQKPEGEPQQDPGTEETYGE 450
E++E +++KEE + K E+ E EE E E + E + Q++ E +
Sbjct: 399 MWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKK 458
Query: 451 VEEEPLDEAQDDDLDELMEME 471
+ EE +E + +++ + E
Sbjct: 459 MREE--EETMREQEEKMQKQE 477
Score = 48.5 bits (114), Expect = 2e-05
Identities = 38/164 (23%), Positives = 84/164 (51%), Gaps = 27/164 (16%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKE--------- 384
++EE EE + +++ R ++Q ++M+ ++ M E+EE+E +++
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500
Query: 385 ---EEMKKKEEKEEEEEEEMKQKEE----------EEEIRNKN----EEEGESKDEEDED 427
E+M+++EEK E+EE+++ +EE +E++R + E+E + +D+E +
Sbjct: 501 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 428 EDGGQKPEGEPQ-QDPGTEETYGEVEEEPLDEAQDDDLDELMEM 470
D ++ E + Q Q+ T + ++ EE ++ + E EM
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 604
Score = 48.5 bits (114), Expect = 2e-05
Identities = 36/129 (27%), Positives = 67/129 (51%), Gaps = 15/129 (11%)
Query: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393
+E+ E E+ + ++E +DQ ++MR +++M+ +EE+ +EE+M +EEK
Sbjct: 780 HEKMQEQEKIWEQEEKM---------RDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830
Query: 394 EEEEEEEMKQKEE----EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDP--GTEET 447
+EE+M +EE +EE + + E K E E++ GQ+ + Q++ G EE
Sbjct: 831 MWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Query: 448 YGEVEEEPL 456
V P+
Sbjct: 891 IYCVGSPPI 899
Score = 47.8 bits (112), Expect = 3e-05
Identities = 29/105 (27%), Positives = 61/105 (58%), Gaps = 6/105 (5%)
Query: 350 QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEE 409
+E R ++Q K++R +++M +EE ++E +M+++EEK +E+ + +E+E+E
Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRL--REQEKE 329
Query: 410 IRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
+R + +E E K+ +++E ++ E +Q EE E EE+
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQ----EEKMREQEEK 370
Score = 47.0 bits (110), Expect = 5e-05
Identities = 30/138 (21%), Positives = 77/138 (55%), Gaps = 16/138 (11%)
Query: 337 ESEDEEYYSEDEDQEARRHRLHSKDQR---------KRMRAFQQEMKEKEEEEMKKEEEM 387
+ ++E+ + ++E + + ++ ++++ ++ R +Q+ K E E+M+++E+M
Sbjct: 620 QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679
Query: 388 KKKEEKE-EEEEEEMKQKEEE----EEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDP 442
+++EEK E+E+ E K +E+E ++ + + EE ++++ +E+ + + E Q+
Sbjct: 680 QEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQE- 738
Query: 443 GTEETYGEVEEEPLDEAQ 460
EE E EEE ++ +
Sbjct: 739 -QEEKMQEQEEEMWEQEE 755
Score = 46.6 bits (109), Expect = 6e-05
Identities = 33/126 (26%), Positives = 64/126 (50%), Gaps = 9/126 (7%)
Query: 337 ESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK--- 393
ESE E ++ + + R + + Q+EM +EEE ++E++++K+EEK
Sbjct: 238 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR 297
Query: 394 --EEEEEEEMKQKEEEEEI----RNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
E E+E K +E+EE++ + E+E E +++E E + + E E Q E+
Sbjct: 298 QEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKM 357
Query: 448 YGEVEE 453
+ + E+
Sbjct: 358 WEQEEK 363
Score = 43.9 bits (102), Expect = 4e-04
Identities = 25/129 (19%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 337 ESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMK-----KKE 391
+ ++E+ + ++E + ++ + + + E ++ +E+E +E+E K K E
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 392 EKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
+K +E+E++ +E+ E + E E + ++EE+ + +K + + ++ EE E
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ 753
Query: 452 EEEPLDEAQ 460
EE+ ++ +
Sbjct: 754 EEKMWEQEE 762
Score = 43.1 bits (100), Expect = 7e-04
Identities = 33/130 (25%), Positives = 70/130 (53%), Gaps = 11/130 (8%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQ--EMKEK--------EEEEM-KK 383
EE+ +++E +++++E +Q ++M Q+ E KEK E+E++ ++
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Query: 384 EEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPG 443
EE+M+ +EEK +EE+M+ +EE+ + + E K E++ GQ+ + Q++
Sbjct: 793 EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 444 TEETYGEVEE 453
E+ G+ E+
Sbjct: 853 EEKMQGQEEK 862
Score = 31.6 bits (70), Expect = 2.0
Identities = 31/137 (22%), Positives = 63/137 (45%), Gaps = 18/137 (13%)
Query: 351 EARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEE------------E 398
E R+ + +++ +K+ Q+++ E E+ + + +K+ + K E +
Sbjct: 212 ELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 271
Query: 399 EEMKQKEE---EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEP---QQDPGTEETYGEVE 452
EEM ++EE E+E + + +EE + EE E G+ E E +Q+ E E+
Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR 331
Query: 453 EEPLDEAQDDDLDELME 469
E+ + + +L E E
Sbjct: 332 EQEKELREQKELREQEE 348
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 63.2 bits (152), Expect = 6e-10
Identities = 33/130 (25%), Positives = 76/130 (58%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ D+E +++++ R ++Q +++R +++++E+EE ++EE+M ++EEK
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 622
Query: 395 EEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEE 454
E+EE+M+++EE+ + + E E K E E++ Q+ + Q++ E+ E+E
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682
Query: 455 PLDEAQDDDL 464
+ Q++ +
Sbjct: 683 EKMQEQEEKM 692
Score = 60.8 bits (146), Expect = 3e-09
Identities = 37/126 (29%), Positives = 73/126 (57%), Gaps = 6/126 (4%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ ++ E ++++++ R ++Q ++MR ++ M EKEE+ ++EE M +KEEK
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 395 EEEEEEMKQKEEE-EEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGT-----EETY 448
+EE M +KEE+ E+ K E+ + +++E++ ++ + E E +Q+ EE
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 449 GEVEEE 454
E EE+
Sbjct: 487 REQEEK 492
Score = 60.8 bits (146), Expect = 3e-09
Identities = 37/137 (27%), Positives = 80/137 (58%), Gaps = 4/137 (2%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ ++E +++++ R +++Q ++M +++M E+EE+ ++EE+M+++EEK
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 395 EEEEEEMKQKEEEEEIRNKNE--EEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
E+E+ K +E+EE+IR + E +E E K E E++ Q+ + + Q++ + E
Sbjct: 644 REQEK--KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 701
Query: 453 EEPLDEAQDDDLDELME 469
+E Q++ + E E
Sbjct: 702 QEVRLRQQEEKMQEHQE 718
Score = 57.0 bits (136), Expect = 5e-08
Identities = 35/135 (25%), Positives = 78/135 (57%), Gaps = 11/135 (8%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
+E+ +EE E E+ + ++ +++ R + +++ E+EE+ K+EE+M ++EEK
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK---EKIHEQEEKIRKQEEKMWRQEEKM 566
Query: 395 EEEEEEMKQKEE-----EEEIRNKNEEEGESKDEEDEDEDGGQKPE---GEPQQDPGTEE 446
++EE+++++EE EE+IR + E+ E +++ E E+ Q+ E GE ++ +E
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 626
Query: 447 TYGEVEEEPLDEAQD 461
+ +EE + ++
Sbjct: 627 EKMQEQEEKMRRQEE 641
Score = 56.2 bits (134), Expect = 8e-08
Identities = 39/154 (25%), Positives = 83/154 (53%), Gaps = 19/154 (12%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKD------------QRKRMRAFQQEMKEKEEEEMK 382
EE EE E E+ ++ ++H ++ Q ++M +++++E+EE+ +
Sbjct: 523 EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWR 582
Query: 383 KEEEMKKKEEKEEEEEEEMKQKE----EEEEIRNKNEE---EGESKDEEDEDEDGGQKPE 435
+EE+++++EEK E+EE+++++E E+EE + EE E E K +E E++ Q+ +
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 436 GEPQQDPGTEETYGEVEEEPLDEAQDDDLDELME 469
Q+ E+ E+E + + Q++ + E E
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 676
Score = 55.5 bits (132), Expect = 1e-07
Identities = 33/131 (25%), Positives = 76/131 (58%), Gaps = 10/131 (7%)
Query: 336 EESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEE 395
+E + +E+ + ++QE + ++Q +++R +++M+ +EE +KEE+M+++EE
Sbjct: 366 QEEKIQEWEEKIQEQEEK-----IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 420
Query: 396 EEEEEMKQKEE-----EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGE 450
E+EE+M+++EE EE+IR E+ E + +++E ++ + Q+ +E
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 480
Query: 451 VEEEPLDEAQD 461
+EE + E ++
Sbjct: 481 RQEEKIREQEE 491
Score = 55.5 bits (132), Expect = 1e-07
Identities = 48/164 (29%), Positives = 85/164 (51%), Gaps = 29/164 (17%)
Query: 335 EEESEDEEYYSEDE---DQEARRHRLHSK--DQRKRMRAFQQEMKEKEE----------E 379
EE+ ++EE E E +QEA+ R K +Q +++R +++M +EE E
Sbjct: 457 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREE 516
Query: 380 EMKKE-EEMKKKEEKEEEEEEEMKQK----EEEEEIRNKNEE---------EGESKDEED 425
E ++E EEM ++EEK E+EE +QK E+EE+IR + E+ + E K E
Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ 576
Query: 426 EDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELME 469
E++ Q+ + Q++ E+ E+E + + Q++ + E E
Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620
Score = 55.1 bits (131), Expect = 2e-07
Identities = 38/144 (26%), Positives = 74/144 (51%), Gaps = 7/144 (4%)
Query: 335 EEESEDEEYYSEDED----QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK 390
E+ E EE + E+ QE + H K + + + ++QE K +E+EE +E+E K +
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR 602
Query: 391 EEKEEEEEEEMKQKEEEE---EIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
E++E +E+E K E+EE E K +E+ E ++E +K E ++ +E
Sbjct: 603 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Query: 448 YGEVEEEPLDEAQDDDLDELMEME 471
+ +EE + E ++ ++ +M+
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQ 686
Score = 53.9 bits (128), Expect = 4e-07
Identities = 33/124 (26%), Positives = 70/124 (56%), Gaps = 2/124 (1%)
Query: 337 ESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE 396
+ ++E+ + ++E + ++ ++Q +++R +++++E+EE+ ++EE M +KEEK
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKI--QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414
Query: 397 EEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPL 456
+EE M +KEE+ + + E E K E E++ Q+ E ++ EE E E+
Sbjct: 415 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 474
Query: 457 DEAQ 460
EA+
Sbjct: 475 QEAK 478
Score = 53.9 bits (128), Expect = 4e-07
Identities = 34/133 (25%), Positives = 73/133 (54%), Gaps = 9/133 (6%)
Query: 337 ESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEE 396
E E++ + E++ E + R K Q + Q+E ++EE +++E++ ++EEK +
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 397 EEEEMKQKEE-----EEEIRNKNE----EEGESKDEEDEDEDGGQKPEGEPQQDPGTEET 447
+EE+M ++EE EE+IR + E +E + +++E++ + +K + + EE
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 448 YGEVEEEPLDEAQ 460
GE EE+ ++ +
Sbjct: 615 MGEQEEKMCEQEE 627
Score = 52.0 bits (123), Expect = 1e-06
Identities = 30/129 (23%), Positives = 72/129 (55%), Gaps = 2/129 (1%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEE--EEMKKEEEMKKKEE 392
EE+ +E +++++ RR ++ +++R +++M E+E+ E+ +K +E +K E
Sbjct: 409 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 468
Query: 393 KEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVE 452
+E+ +E+E K +EE+IR + E+ E +++ E+ + E +++ E+ +
Sbjct: 469 QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 528
Query: 453 EEPLDEAQD 461
EE + E ++
Sbjct: 529 EEKIREQEE 537
Score = 50.1 bits (118), Expect = 6e-06
Identities = 39/113 (34%), Positives = 64/113 (56%), Gaps = 12/113 (10%)
Query: 335 EEESEDEEYYSEDED--QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEM--KKEEEMKKK 390
EE+ ++E E E+ QE + R K Q + + ++QE K +E+EE ++EE+M ++
Sbjct: 444 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 391 EEK-EEEE---EEEMKQKEEE----EEIRNKNEEEGESKDEEDEDEDGGQKPE 435
EEK E+E EEE +Q++EE EE + EE K++ E E+ +K E
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556
Score = 49.7 bits (117), Expect = 7e-06
Identities = 38/147 (25%), Positives = 79/147 (53%), Gaps = 18/147 (12%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMK---KEEEMKKKEEKEE 395
E EE E E++ + ++ ++++++ +E ++++E+E K +EE+++++EEK
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 396 EEEEEMKQKEE---------EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEE 446
E+EE+M ++EE EEE R + EE +++ E E+ ++ E +Q EE
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ----EE 550
Query: 447 TYGEVEEE--PLDEAQDDDLDELMEME 471
+ EE+ +E D +++ E E
Sbjct: 551 KIRKQEEKMWRQEEKMHDQEEKIREQE 577
Score = 48.9 bits (115), Expect = 1e-05
Identities = 22/82 (26%), Positives = 53/82 (64%)
Query: 335 EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKE 394
EE+ ++E +++++ R ++Q ++M +++M E+EE+ ++EE+M+++EEK
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Query: 395 EEEEEEMKQKEEEEEIRNKNEE 416
E+E ++Q+EE+ + ++ E
Sbjct: 700 WEQEVRLRQQEEKMQEHQEHLE 721
Score = 46.2 bits (108), Expect = 8e-05
Identities = 31/123 (25%), Positives = 70/123 (56%), Gaps = 7/123 (5%)
Query: 339 EDEEYYSEDEDQEARRHRLHSKDQ-RKRMRAFQQEMKEKEEEEMKKEE-EMKKKEEKEEE 396
++E + ++E ++H +++ R++ Q+E K +E+E+ +++E +M ++EEK E
Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 488
Query: 397 EEEEMKQKEE-----EEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
+EE+++++EE EE+I + + E K +E E+ ++ E ++ +E E
Sbjct: 489 QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548
Query: 452 EEE 454
EE+
Sbjct: 549 EEK 551
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/127 (27%), Positives = 70/127 (55%), Gaps = 13/127 (10%)
Query: 355 HRLHSKDQRKRMRAFQ--QEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEE-----E 407
+RL+ + + K R + QE +EK +E+ EE+++++EEK E+EE+M+++EE E
Sbjct: 353 NRLNQQQEEKMWRQEEKIQEWEEKIQEQ---EEKIREQEEKIREQEEKMRRQEEMMWEKE 409
Query: 408 EEIRNKNEEEGESKDEEDEDEDGGQKPE---GEPQQDPGTEETYGEVEEEPLDEAQDDDL 464
E++R + E E +++ E+ + E E ++ +E E EE+ +E + +
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 465 DELMEME 471
++ E E
Sbjct: 470 EKRQEQE 476
Score = 34.7 bits (78), Expect = 0.24
Identities = 27/88 (30%), Positives = 50/88 (56%), Gaps = 8/88 (9%)
Query: 370 QQEMKEKE---EEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDE 426
Q +++E E ++EE+M ++EEK +E EE K +E+EE+IR + E+ E +++
Sbjct: 343 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE--KIQEQEEKIREQEEKIREQEEKMRR 400
Query: 427 DEDGGQKPEGEPQQDPGTEETYGEVEEE 454
E+ + E + ++ EE E EE+
Sbjct: 401 QEEMMWEKEEKMRRQ---EEMMWEKEEK 425
Score = 29.6 bits (65), Expect = 7.8
Identities = 28/116 (24%), Positives = 56/116 (48%), Gaps = 6/116 (5%)
Query: 345 SEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQ- 403
SE + + L K +R ++ QQ+++ + + K+ + + K + + EE E +
Sbjct: 296 SEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 355
Query: 404 KEEEEEIRNKNEE---EGESKDEEDEDEDGGQKPEGEPQQDP--GTEETYGEVEEE 454
+++EE + EE E E K +E E++ Q+ + Q++ EE E EE+
Sbjct: 356 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 411
>gi|6912480 leucine zipper, down-regulated in cancer 1 [Homo
sapiens]
Length = 146
Score = 63.2 bits (152), Expect = 6e-10
Identities = 32/87 (36%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
Query: 142 QPPLAPLERPEIEPFSGDPVYLAEFLMQLETFIADHEVHFPGGAERVAFLISFFTGEAKD 201
+PP P+ PE F+G+ L EF++Q +++ +E F A +VAFLIS TGEA++
Sbjct: 45 RPPSCPVPFPET--FNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEE 102
Query: 202 WAISVTQEGSPLHANFPRFLDEIRKEF 228
W + + SP+ ++ FLDE+++ F
Sbjct: 103 WVVPYIEMDSPILGDYRAFLDEMKQCF 129
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 62.4 bits (150), Expect = 1e-09
Identities = 40/139 (28%), Positives = 71/139 (51%), Gaps = 9/139 (6%)
Query: 335 EEESE----DEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK 390
+EESE DE ED+DQ+ +R R+ S+++ R ++ + K +KEEE +K
Sbjct: 197 QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEK 256
Query: 391 EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDP---GTEET 447
EEK + K+ +++++ + + E + + DEDEDG +K E + + P +
Sbjct: 257 EEK--RLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRR 314
Query: 448 YGEVEEEPLDEAQDDDLDE 466
E E E ++ D+ DE
Sbjct: 315 PEEKEPEKVNPQISDEKDE 333
Score = 41.2 bits (95), Expect = 0.003
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 24/143 (16%)
Query: 307 IERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRM 366
+ + RV +P+P A S E E+E +++E +R R +K+ +
Sbjct: 223 VTSRERVARPLPAEEPER-----AKSGTRTEKEEER-----DEKEEKRLRSQTKEPTPK- 271
Query: 367 RAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEE---------MKQKEEEEEIRNKNEEE 417
Q++KE+ + E + + + E+ +E++E++ K++ EE+E N +
Sbjct: 272 ----QKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQI 327
Query: 418 GESKDEEDEDEDGGQKPEGEPQQ 440
+ KDE++++E + EP +
Sbjct: 328 SDEKDEDEKEEKRRKTTPKEPTE 350
Score = 35.8 bits (81), Expect = 0.11
Identities = 34/140 (24%), Positives = 64/140 (45%), Gaps = 22/140 (15%)
Query: 331 PSPNEEESEDEEYYS-------EDED---QEARRHRLHSKDQRKRMRAFQQEMKEKEEEE 380
P+P ++ E+ + + EDED ++ ++HR KD + R +EKE E+
Sbjct: 268 PTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP-----EEKEPEK 322
Query: 381 MKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
+ + +K E+++EE+ + KE E+ + + SK + GQ +
Sbjct: 323 VNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLD----- 377
Query: 441 DPGTEETYGEVEEEPLDEAQ 460
DP + YG+ + +DE Q
Sbjct: 378 DPDLK--YGQHPPDAVDEPQ 395
Score = 34.7 bits (78), Expect = 0.24
Identities = 29/138 (21%), Positives = 52/138 (37%), Gaps = 6/138 (4%)
Query: 376 KEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPE 435
K + K +EE ++ + E +EE+ Q E+ + ++ EE E G + E
Sbjct: 189 KGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE 248
Query: 436 GEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENFLG 495
E ++D E+ +EP + +L E A Q G +
Sbjct: 249 KEEERDEKEEKRLRSQTKEPTPK------QKLKEEPDREARAGVQADEDEDGDEKDEKKH 302
Query: 496 ASPPIIQPSRRRNQNRVP 513
S P ++RR + + P
Sbjct: 303 RSQPKDLAAKRRPEEKEP 320
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 62.0 bits (149), Expect = 1e-09
Identities = 63/241 (26%), Positives = 104/241 (43%), Gaps = 26/241 (10%)
Query: 305 VEIERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRL--HSKDQ 362
+ I K++ PK + P ++ + F EE ++E +E A L K++
Sbjct: 430 ITISSKIQKPK-VEAPKLK-VQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEE 487
Query: 363 RKRMRAFQQEMKEKEEEEM--------------KKEEEMKKKEEKEEEEEEEMKQKEEEE 408
+K ++E E EEEE+ K+EE K++EE +EEEEEE + + ++
Sbjct: 488 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 547
Query: 409 EIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELM 468
+E+EG S+ EE E E+G + E E ++ EE +VEE+ + A ++L
Sbjct: 548 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEK--KVEEKSEEVATKEELVADA 605
Query: 469 EMEPTFVHASSQTSGPTSGYHAENFLGASPPIIQPSRRRNQNRVPLLEGLPGTNSPFYSS 528
++E S P G SP P + ++ VP SP S
Sbjct: 606 KVEKPEKAKSPVPKSPVEE------KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 659
Query: 529 P 529
P
Sbjct: 660 P 660
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/173 (27%), Positives = 80/173 (46%), Gaps = 38/173 (21%)
Query: 305 VEIERKVRVPK-PIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQR 363
VE + K VPK P+ G P + SP EE+++ S E+ +K +
Sbjct: 648 VEEKGKSPVPKSPVEEKGKS----PVSKSPVEEKAKSPVPKSPVEE---------AKSKA 694
Query: 364 KRMRAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEE-------------- 409
+ + Q+E +EKE +E KEE+++KKEEK ++ E+ K + +E
Sbjct: 695 EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 754
Query: 410 --IRNKNEEEGESKDEEDEDE----DGGQKPEGEPQQDPGTEE----TYGEVE 452
+ + +EEG+ +E E E +GG + EG + G+ + GEVE
Sbjct: 755 VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVE 807
Score = 43.1 bits (100), Expect = 7e-04
Identities = 44/167 (26%), Positives = 76/167 (45%), Gaps = 18/167 (10%)
Query: 291 STEMADLDELILECVEIERKVRVPKPIPLPGVRNI-IFPFAPSPNEEESEDEEYYSEDED 349
S E+A +EL+ + ++E+ + P+P V P SP EE+ + S E+
Sbjct: 592 SEEVATKEELVADA-KVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEE 650
Query: 350 QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKE--EEMKKKEEK---EEEEEEEMKQK 404
+ +++ + + ++EK + + K EE K K E E++EEEE + K
Sbjct: 651 KGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK 710
Query: 405 EEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGEV 451
E + EE+ E K+E+ +D PE + + P EE EV
Sbjct: 711 EAPK------EEKVEKKEEKPKD-----VPEKKKAESPVKEEAVAEV 746
Score = 33.9 bits (76), Expect = 0.41
Identities = 32/139 (23%), Positives = 59/139 (42%), Gaps = 16/139 (11%)
Query: 332 SPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMK------EKEEEEMKKEE 385
+P EE+ E +E +D ++ + ++ + + +K KEE + ++E
Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771
Query: 386 EMKKKEEKEEEEEEEMKQK----EEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEP--- 438
+ K+K E EEE K +E+I E EG+ + E++ E G + E +
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831
Query: 439 ---QQDPGTEETYGEVEEE 454
P E+ G+ EE
Sbjct: 832 NGLDLSPADEKKGGDKSEE 850
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.135 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,399,107
Number of Sequences: 37866
Number of extensions: 2010232
Number of successful extensions: 114865
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2021
Number of HSP's successfully gapped in prelim test: 1347
Number of HSP's that attempted gapping in prelim test: 22346
Number of HSP's gapped (non-prelim): 38046
length of query: 569
length of database: 18,247,518
effective HSP length: 108
effective length of query: 461
effective length of database: 14,157,990
effective search space: 6526833390
effective search space used: 6526833390
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.