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Search of human proteins with 66346685
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66346685 SERPINE1 mRNA binding protein 1 isoform 4 [Homo
sapiens]
(387 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66346685 SERPINE1 mRNA binding protein 1 isoform 4 [Homo sapi... 798 0.0
gi|66346683 SERPINE1 mRNA binding protein 1 isoform 3 [Homo sapi... 791 0.0
gi|66346681 SERPINE1 mRNA binding protein 1 isoform 2 [Homo sapi... 788 0.0
gi|66346679 SERPINE1 mRNA binding protein 1 isoform 1 [Homo sapi... 781 0.0
gi|157676331 hyaluronan binding protein 4 [Homo sapiens] 259 2e-69
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 55 1e-07
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 48 1e-05
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 48 1e-05
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 47 4e-05
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 43 6e-04
gi|153791630 bromodomain and WD repeat domain containing 3 [Homo... 42 7e-04
gi|9966841 cell death regulator aven [Homo sapiens] 41 0.002
gi|62988361 absent in melanoma 1 [Homo sapiens] 41 0.002
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 41 0.002
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 40 0.003
gi|15011916 nucleolar protein family A, member 1 [Homo sapiens] 40 0.003
gi|9506713 nucleolar protein family A, member 1 [Homo sapiens] 40 0.003
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 40 0.003
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 40 0.003
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 40 0.004
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 40 0.004
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.004
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.004
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.004
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 40 0.004
gi|239744552 PREDICTED: hypothetical protein [Homo sapiens] 39 0.006
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 39 0.006
gi|169217514 PREDICTED: Inactive ubiquitin carboxyl-terminal hyd... 39 0.008
gi|169163728 PREDICTED: hypothetical protein [Homo sapiens] 39 0.008
gi|239749360 PREDICTED: Inactive ubiquitin carboxyl-terminal hyd... 39 0.008
>gi|66346685 SERPINE1 mRNA binding protein 1 isoform 4 [Homo
sapiens]
Length = 387
Score = 798 bits (2060), Expect = 0.0
Identities = 387/387 (100%), Positives = 387/387 (100%)
Query: 1 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ 60
MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
Sbjct: 1 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ 60
Query: 61 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE 120
TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
Sbjct: 61 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE 120
Query: 121 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
Sbjct: 121 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG
Sbjct: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
Query: 241 EEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWKK 300
EEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWKK
Sbjct: 241 EEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWKK 300
Query: 301 GFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGR 360
GFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGR
Sbjct: 301 GFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGR 360
Query: 361 PNRGSRTDKSSASAPDVDDPEAFPALA 387
PNRGSRTDKSSASAPDVDDPEAFPALA
Sbjct: 361 PNRGSRTDKSSASAPDVDDPEAFPALA 387
>gi|66346683 SERPINE1 mRNA binding protein 1 isoform 3 [Homo
sapiens]
Length = 393
Score = 791 bits (2043), Expect = 0.0
Identities = 387/393 (98%), Positives = 387/393 (98%), Gaps = 6/393 (1%)
Query: 1 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ 60
MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
Sbjct: 1 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ 60
Query: 61 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE 120
TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
Sbjct: 61 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE 120
Query: 121 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
Sbjct: 121 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
Query: 181 RGDGFDSRGKREFDRHSGSDR------SGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT 234
RGDGFDSRGKREFDRHSGSDR SGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT
Sbjct: 181 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVT 240
Query: 235 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA 294
EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA
Sbjct: 241 EETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA 300
Query: 295 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG 354
DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG
Sbjct: 301 DGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGG 360
Query: 355 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA 387
RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
Sbjct: 361 RGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA 393
>gi|66346681 SERPINE1 mRNA binding protein 1 isoform 2 [Homo
sapiens]
Length = 402
Score = 788 bits (2034), Expect = 0.0
Identities = 387/402 (96%), Positives = 387/402 (96%), Gaps = 15/402 (3%)
Query: 1 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ 60
MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
Sbjct: 1 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ 60
Query: 61 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE 120
TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
Sbjct: 61 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE 120
Query: 121 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
Sbjct: 121 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELT-------------- 226
RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELT
Sbjct: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQKQISYNY 240
Query: 227 -DLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEF 285
DLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEF
Sbjct: 241 SDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEF 300
Query: 286 NIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPG 345
NIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPG
Sbjct: 301 NIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPG 360
Query: 346 RGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA 387
RGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
Sbjct: 361 RGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA 402
>gi|66346679 SERPINE1 mRNA binding protein 1 isoform 1 [Homo
sapiens]
Length = 408
Score = 781 bits (2017), Expect = 0.0
Identities = 387/408 (94%), Positives = 387/408 (94%), Gaps = 21/408 (5%)
Query: 1 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ 60
MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ
Sbjct: 1 MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQ 60
Query: 61 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE 120
TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE
Sbjct: 61 TNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGE 120
Query: 121 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG
Sbjct: 121 GKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
Query: 181 RGDGFDSRGKREFDRHSGSDR------SGLKHEDKRGGSGSHNWGTVKDELT-------- 226
RGDGFDSRGKREFDRHSGSDR SGLKHEDKRGGSGSHNWGTVKDELT
Sbjct: 181 RGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQK 240
Query: 227 -------DLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD 279
DLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD
Sbjct: 241 QISYNYSDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD 300
Query: 280 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG 339
RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG
Sbjct: 301 RAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFG 360
Query: 340 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA 387
DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA
Sbjct: 361 DLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPEAFPALA 408
>gi|157676331 hyaluronan binding protein 4 [Homo sapiens]
Length = 413
Score = 259 bits (663), Expect = 2e-69
Identities = 178/412 (43%), Positives = 228/412 (55%), Gaps = 43/412 (10%)
Query: 5 LQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKE----------AGGGGVGGPGAKSA 54
+QE FGCVV NRF QL DDESDPF++L+ AE ++++ A G G G +S
Sbjct: 16 MQESFGCVVANRFHQLLDDESDPFDILREAERRRQQQLQRKRRDEAAAAAGAGPRGGRSP 75
Query: 55 AQAAAQTNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPD 114
A A+ + AG R+ESQK+RK+ LP V + P L+ G +R RR +
Sbjct: 76 AGASG----HRAGAGGRRESQKERKS-LPAPVA----QRPDSPGGGLQAPGQKRTPRRGE 126
Query: 115 QQLQGEGKIIDRRPERRPPRERRFEKPLEEKGEGG--------EFSVDRPIIDRPIRGRG 166
QQ + + + ER R R +P E + + E DR DRP+RGRG
Sbjct: 127 QQGWNDSRGPEGMLERAERRSYREYRPYETERQADFTAEKFPDEKPGDRFDRDRPLRGRG 186
Query: 167 GLGRGRGGRGRGMGRG----DGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVK 222
G G GRGRG G G D FD RGKREF+R+ G+D+ ++ ED GG G WG+ K
Sbjct: 187 GPRGGMRGRGRG-GPGNRVFDAFDQRGKREFERYGGNDKIAVRTEDNMGGCGVRTWGSGK 245
Query: 223 DELTDLDQSNVTEETPEGEEHHPVADTEN--KENEVEEVKEEGPKEMTLDEWKAIQNKDR 280
D +D++ + EE EE + E+ K E+E +E +EMTLDEWK +Q + R
Sbjct: 246 DT-SDVEPTAPMEEPTVVEESQGTPEEESPAKVPELEVEEETQVQEMTLDEWKNLQEQTR 304
Query: 281 AKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMD--HHFRKPANDITSQLEINF 338
K EFNIRKP K V+HKSK + +D D H FRKPANDITSQLEINF
Sbjct: 305 PKPEFNIRKPESTVPS---KAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDITSQLEINF 361
Query: 339 GDLGRPGRGGRGG-RGGRGRGGR-PNRGSRTDKSSAS-APDVDDPEAFPALA 387
G+L RPGRG RGG RGGRGR R N G R + AP+ DDPE FPAL+
Sbjct: 362 GNLPRPGRGARGGTRGGRGRIRRAENYGPRAEVVMQDVAPNPDDPEDFPALS 413
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 54.7 bits (130), Expect = 1e-07
Identities = 62/256 (24%), Positives = 101/256 (39%), Gaps = 38/256 (14%)
Query: 20 LFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRK 79
L DD +D EV +E K K G G G + + + R++ +KD+
Sbjct: 626 LSDDLTDKAEV---SEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKG 682
Query: 80 NPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFE 139
G +++ E + +A K+E +R G +Q+ + +G +R E E
Sbjct: 683 R------GEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGE---- 732
Query: 140 KPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDGFDSRGKRE------- 192
EE GEG E DR + G G G+G + G+RE
Sbjct: 733 ---EEHGEGEEEEGDREEEEEK-------------EGEGKEEGEGEEVEGEREKEEGERK 776
Query: 193 FDRHSGSDRSGLKHEDKRGG--SGSHNWGTVKDELTDLDQSNVTEETPEGEEHHPVADTE 250
+ +G + G + D+ G + G K+E +++ V E E EE + E
Sbjct: 777 KEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGE 836
Query: 251 NKENEVEEVKEEGPKE 266
+E E EE + EG +E
Sbjct: 837 EEEGEGEEEEGEGEEE 852
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/290 (21%), Positives = 113/290 (38%), Gaps = 13/290 (4%)
Query: 35 ENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEE 94
E ++K+ G G + Q + + ++E + + G +++EE
Sbjct: 772 EGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEE 831
Query: 95 TQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEEKGEG-GEFSV 153
+ EG G +++ +G+G+ E E + EE+GEG GE
Sbjct: 832 EGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG 891
Query: 154 DRPIIDRPIRGRG-----GLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSGLKHED 208
+ + G G G G G G+G G+ + G+ E G D G E+
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951
Query: 209 KRGGSGSHNWGTVKDELTDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMT 268
+ G G + E + + E EGEE + E +E E EE +EEG E
Sbjct: 952 EGEWEGEEEEGEGEGE--EEGEGEGEEGEGEGEEEEGEGEGEEEEGE-EEGEEEGEGE-- 1006
Query: 269 LDEWKAI-QNKDRAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDS 317
+E + + ++ +VE + +G+ ++G + + +E E++
Sbjct: 1007 -EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055
Score = 46.2 bits (108), Expect = 5e-05
Identities = 67/290 (23%), Positives = 106/290 (36%), Gaps = 30/290 (10%)
Query: 35 ENKKKEAGGGGVG------GPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKNPLPPSVGV 88
E K +E G G G G G + + GK R+E +++ + G
Sbjct: 784 EEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGE 843
Query: 89 VDKKE--ETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEEKG 146
++ E E + ++EG G ++ +GEG+ + E E E EE+G
Sbjct: 844 EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGE---EEEG 900
Query: 147 EG-----GEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDR 201
EG GE + + G G G G G G G+ + G+ E G +
Sbjct: 901 EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960
Query: 202 SGLKHEDKRG--------GSGSHNWGTVKDELTDLDQSNVTEETPEGEEHHPVADTENKE 253
G ++ G G G G + E + ++ EE EGEE E +E
Sbjct: 961 EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEG--EEEGEGEEEGEGEGEEEEE 1018
Query: 254 NEVEE----VKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWK 299
EVE + EG E E + + + + E N R E + + K
Sbjct: 1019 GEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGK 1068
Score = 45.4 bits (106), Expect = 8e-05
Identities = 62/264 (23%), Positives = 98/264 (37%), Gaps = 48/264 (18%)
Query: 35 ENKKKEAGGGGVG--------GPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKNPLPPSV 86
E K +E G G G G G + + + G++ E + + +
Sbjct: 855 EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE----- 909
Query: 87 GVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEE-K 145
+ EE + ++EG G +++ +GEG+ + E E +E EE +
Sbjct: 910 ---GEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE---EGEWEGEEEEGE 963
Query: 146 GEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGM---GRGDGFDSRGKREFDRHSGSDRS 202
GEG E G G G G G G G G+G + G+ E +
Sbjct: 964 GEGEE---------------EGEGEGEEGEGEGEEEEGEGEGEEEEGEEE------GEEE 1002
Query: 203 GLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETP---EGEEHHPVAD-TENKENEVEE 258
G E+ G G V+ E+ + EE EGEE + EN+ N EE
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEE 1062
Query: 259 VKEEGPKEMTLDEWKAIQNKDRAK 282
+EEG + T +E Q+ + K
Sbjct: 1063 EEEEGKYQETGEEENERQDGEEYK 1086
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 48.1 bits (113), Expect = 1e-05
Identities = 61/210 (29%), Positives = 84/210 (40%), Gaps = 23/210 (10%)
Query: 160 RPIRGRGGLGRGRGG-RGRGMGRGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNW 218
R + G RG GG +G G GRG G+D G+ SG DR G K+ GG +
Sbjct: 162 RDVSRYGEDNRGYGGSQGGGRGRG-GYDKDGRGPMTGSSGGDRGGFKN---FGGHRDYGP 217
Query: 219 GTVKDELTDLDQSNV--TEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAI- 275
T D +D +N + EG V + + ++ K+ G + L K
Sbjct: 218 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 277
Query: 276 QNKDRAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLE 335
+ K A V F+ P+ A W G +E H + R+P +
Sbjct: 278 KPKGEATVSFD-DPPSAKAAIDWFDG--------KEFHGNIIKVSFATRRP-----EFMR 323
Query: 336 INFGDLGRPGRGGRGGRGG-RGRGGRPNRG 364
GR GRGG GRGG +GRGG P G
Sbjct: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 353
Score = 36.2 bits (82), Expect = 0.051
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 19/83 (22%)
Query: 140 KPLEEKGEGGEFSVDRPIIDRPIRGRGGLG----RGRGGRGRGMGRGDGFDSRGKREFDR 195
+P + + GG+F RGRG G RGRGGRG G G S G DR
Sbjct: 380 RPEDSRPSGGDF-----------RGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDR 428
Query: 196 HSG----SDRSGLKHEDKRGGSG 214
SG DRSG + R G G
Sbjct: 429 SSGGGYSGDRSGGGYGGDRSGGG 451
Score = 34.3 bits (77), Expect = 0.20
Identities = 32/86 (37%), Positives = 35/86 (40%), Gaps = 7/86 (8%)
Query: 129 ERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRG--RGGLGRGRGGRGRGMGRGDGFD 186
E RP R +G GGE R R RG RGG G R G G G R G
Sbjct: 378 EPRPEDSRPSGGDFRGRGYGGE----RGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGG 433
Query: 187 SRGKREFDRHSGSDRSGLKHEDKRGG 212
G R + G DRSG + RGG
Sbjct: 434 YSGDRSGGGY-GGDRSGGGYGGDRGG 458
Score = 34.3 bits (77), Expect = 0.20
Identities = 24/52 (46%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
Query: 165 RGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGS----DRSGLKHEDKRGG 212
RGG G RGG G G G SRG DR GS DRSG D+ GG
Sbjct: 502 RGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGG 553
Score = 33.1 bits (74), Expect = 0.44
Identities = 24/56 (42%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 165 RGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHS-GSDRSGLKHEDKRGGSGSHNWG 219
RGG G RGG G G RG RG DR G DR G + RGG G G
Sbjct: 480 RGGYGGDRGG-GYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGG 534
Score = 32.0 bits (71), Expect = 0.97
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 20/76 (26%)
Query: 144 EKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSG 203
++ GG +S DR GG G R G G G RG G+ G DR G
Sbjct: 427 DRSSGGGYSGDR--------SGGGYGGDRSGGGYGGDRGGGY------------GGDRGG 466
Query: 204 LKHEDKRGGSGSHNWG 219
D+ GG G G
Sbjct: 467 GYGGDRGGGYGGDRGG 482
Score = 30.8 bits (68), Expect = 2.2
Identities = 19/34 (55%), Positives = 21/34 (61%), Gaps = 2/34 (5%)
Query: 339 GDLGRPGRGGRGG-RGGRGRGGRPNRGSRTDKSS 371
G+ G GRGGRGG RGG G G R G D+SS
Sbjct: 398 GERGYRGRGGRGGDRGGYG-GDRSGGGYGGDRSS 430
Score = 30.4 bits (67), Expect = 2.8
Identities = 27/62 (43%), Positives = 28/62 (45%), Gaps = 8/62 (12%)
Query: 165 RGGLG--RGRGGRG--RGMGRGDGFDSRGKREFDRHS---GSDRSGLKHEDKRGGSGSHN 217
RGG G R RGG G RG G G G D G DR G DR G + RGG G
Sbjct: 516 RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG-GYGGDRGGYGGKM 574
Query: 218 WG 219
G
Sbjct: 575 GG 576
Score = 29.6 bits (65), Expect = 4.8
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 18/87 (20%)
Query: 305 HKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRG-GRGG------------ 351
+ + H++ HH + D++ E N G G G G GRGG
Sbjct: 139 YSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGS 198
Query: 352 ----RGG-RGRGGRPNRGSRTDKSSAS 373
RGG + GG + G RTD S S
Sbjct: 199 SGGDRGGFKNFGGHRDYGPRTDADSES 225
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 48.1 bits (113), Expect = 1e-05
Identities = 61/210 (29%), Positives = 84/210 (40%), Gaps = 23/210 (10%)
Query: 160 RPIRGRGGLGRGRGG-RGRGMGRGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNW 218
R + G RG GG +G G GRG G+D G+ SG DR G K+ GG +
Sbjct: 165 RDVSRYGEDNRGYGGSQGGGRGRG-GYDKDGRGPMTGSSGGDRGGFKN---FGGHRDYGP 220
Query: 219 GTVKDELTDLDQSNV--TEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAI- 275
T D +D +N + EG V + + ++ K+ G + L K
Sbjct: 221 RTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTG 280
Query: 276 QNKDRAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLE 335
+ K A V F+ P+ A W G +E H + R+P +
Sbjct: 281 KPKGEATVSFD-DPPSAKAAIDWFDG--------KEFHGNIIKVSFATRRP-----EFMR 326
Query: 336 INFGDLGRPGRGGRGGRGG-RGRGGRPNRG 364
GR GRGG GRGG +GRGG P G
Sbjct: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSG 356
Score = 36.2 bits (82), Expect = 0.051
Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 19/83 (22%)
Query: 140 KPLEEKGEGGEFSVDRPIIDRPIRGRGGLG----RGRGGRGRGMGRGDGFDSRGKREFDR 195
+P + + GG+F RGRG G RGRGGRG G G S G DR
Sbjct: 383 RPEDSRPSGGDF-----------RGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDR 431
Query: 196 HSG----SDRSGLKHEDKRGGSG 214
SG DRSG + R G G
Sbjct: 432 SSGGGYSGDRSGGGYGGDRSGGG 454
Score = 34.3 bits (77), Expect = 0.20
Identities = 32/86 (37%), Positives = 35/86 (40%), Gaps = 7/86 (8%)
Query: 129 ERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRG--RGGLGRGRGGRGRGMGRGDGFD 186
E RP R +G GGE R R RG RGG G R G G G R G
Sbjct: 381 EPRPEDSRPSGGDFRGRGYGGE----RGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGG 436
Query: 187 SRGKREFDRHSGSDRSGLKHEDKRGG 212
G R + G DRSG + RGG
Sbjct: 437 YSGDRSGGGY-GGDRSGGGYGGDRGG 461
Score = 34.3 bits (77), Expect = 0.20
Identities = 24/52 (46%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
Query: 165 RGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGS----DRSGLKHEDKRGG 212
RGG G RGG G G G SRG DR GS DRSG D+ GG
Sbjct: 505 RGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGG 556
Score = 33.1 bits (74), Expect = 0.44
Identities = 24/56 (42%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 165 RGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHS-GSDRSGLKHEDKRGGSGSHNWG 219
RGG G RGG G G RG RG DR G DR G + RGG G G
Sbjct: 483 RGGYGGDRGG-GYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGG 537
Score = 32.0 bits (71), Expect = 0.97
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 20/76 (26%)
Query: 144 EKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSG 203
++ GG +S DR GG G R G G G RG G+ G DR G
Sbjct: 430 DRSSGGGYSGDR--------SGGGYGGDRSGGGYGGDRGGGY------------GGDRGG 469
Query: 204 LKHEDKRGGSGSHNWG 219
D+ GG G G
Sbjct: 470 GYGGDRGGGYGGDRGG 485
Score = 30.8 bits (68), Expect = 2.2
Identities = 19/34 (55%), Positives = 21/34 (61%), Gaps = 2/34 (5%)
Query: 339 GDLGRPGRGGRGG-RGGRGRGGRPNRGSRTDKSS 371
G+ G GRGGRGG RGG G G R G D+SS
Sbjct: 401 GERGYRGRGGRGGDRGGYG-GDRSGGGYGGDRSS 433
Score = 30.4 bits (67), Expect = 2.8
Identities = 27/62 (43%), Positives = 28/62 (45%), Gaps = 8/62 (12%)
Query: 165 RGGLG--RGRGGRG--RGMGRGDGFDSRGKREFDRHS---GSDRSGLKHEDKRGGSGSHN 217
RGG G R RGG G RG G G G D G DR G DR G + RGG G
Sbjct: 519 RGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG-GYGGDRGGYGGKM 577
Query: 218 WG 219
G
Sbjct: 578 GG 579
Score = 29.6 bits (65), Expect = 4.8
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 18/87 (20%)
Query: 305 HKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRG-GRGG------------ 351
+ + H++ HH + D++ E N G G G G GRGG
Sbjct: 142 YSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGS 201
Query: 352 ----RGG-RGRGGRPNRGSRTDKSSAS 373
RGG + GG + G RTD S S
Sbjct: 202 SGGDRGGFKNFGGHRDYGPRTDADSES 228
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 46.6 bits (109), Expect = 4e-05
Identities = 62/229 (27%), Positives = 82/229 (35%), Gaps = 30/229 (13%)
Query: 143 EEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDG-FDSRGKREFDRHSGSDR 201
++ G GG + DR RGRGG G G GG G G R G ++ RG+ G R
Sbjct: 198 DQSGGGGSGGYGQQ--DRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGR-------GGGR 248
Query: 202 SGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGEEHHPVAD-TENKENEVEEVK 260
G RGG G + G DQ G H D ++N V+ +
Sbjct: 249 GG------RGGMGGSDRGGFNKFGGPRDQ---------GSRHDSEQDNSDNNTIFVQGLG 293
Query: 261 EEGPKEMTLDEWKAI----QNKDRAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAED 316
E E D +K I NK + N+ E + + S +A +
Sbjct: 294 ENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDW 353
Query: 317 SVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGRPNRGS 365
P + +F G GRGGRG G GRGG GS
Sbjct: 354 FDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGS 402
Score = 33.5 bits (75), Expect = 0.33
Identities = 16/37 (43%), Positives = 20/37 (54%)
Query: 345 GRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDPE 381
GRGGRGG GG RGG G D+ S + D+ +
Sbjct: 247 GRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSD 283
Score = 30.4 bits (67), Expect = 2.8
Identities = 45/156 (28%), Positives = 55/156 (35%), Gaps = 29/156 (18%)
Query: 42 GGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKNPLPPSVGV-VDKKEETQPPVA 100
G GG GG G+ + + G Q R D K P P + + E A
Sbjct: 393 GRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAG---DWKCPNPTCENMNFSWRNECNQCKA 449
Query: 101 LKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDR 160
K +G G P G DRR R + +G GG+
Sbjct: 450 PKPDG---PGGGPGGSHMGGNYGDDRRGGRGGYDRGGY------RGRGGD---------- 490
Query: 161 PIRGRGGLGRGRGGRGRGMGRGDG-FDSRGKREFDR 195
RGG GRGG RG G G G DSRG+ DR
Sbjct: 491 ----RGGFRGGRGGGDRG-GFGPGKMDSRGEHRQDR 521
Score = 29.6 bits (65), Expect = 4.8
Identities = 14/23 (60%), Positives = 15/23 (65%)
Query: 337 NFGDLGRPGRGGRGGRGGRGRGG 359
N+GD R GRGG G RGRGG
Sbjct: 467 NYGDDRRGGRGGYDRGGYRGRGG 489
Score = 29.3 bits (64), Expect = 6.3
Identities = 13/28 (46%), Positives = 17/28 (60%)
Query: 338 FGDLGRPGRGGRGGRGGRGRGGRPNRGS 365
+G+ + G GG GG G + RGGR GS
Sbjct: 194 YGNQDQSGGGGSGGYGQQDRGGRGRGGS 221
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 42.7 bits (99), Expect = 6e-04
Identities = 66/262 (25%), Positives = 95/262 (36%), Gaps = 41/262 (15%)
Query: 31 LKAAENKKKEAGGGGVGGPGAKSAA-QAAAQTNSNAAGKQLRKESQKDRKNPLPPSVGVV 89
L E +K A G G GG G ++ +T R+ + P G +
Sbjct: 893 LTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPI 952
Query: 90 DK-----KEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEE 144
K K E PP L++ +PD +GK+ P+ PP P
Sbjct: 953 KKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKL--GGPKETPPNGNLSPAPRLR 1010
Query: 145 KGEGGEFSVDRPIIDRPIRGRGG---LGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDR 201
+ ++S +R + RGRG RGRG RG GRG G SR R + G D
Sbjct: 1011 R----DYSYER-VGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDG 1065
Query: 202 SGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGEEHHPV----------ADTEN 251
G GG+G N T +E EG E+ + +E
Sbjct: 1066 RG-------GGTGGPNHPPAPRGRT------ASETRSEGSEYEEIPKRRRQRGSETGSET 1112
Query: 252 KENEVEEVKEEG--PKEMTLDE 271
E+++ +E PKE TL +
Sbjct: 1113 HESDLAPSDKEAPTPKEGTLTQ 1134
>gi|153791630 bromodomain and WD repeat domain containing 3 [Homo
sapiens]
Length = 1802
Score = 42.4 bits (98), Expect = 7e-04
Identities = 43/159 (27%), Positives = 66/159 (41%), Gaps = 12/159 (7%)
Query: 42 GGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVAL 101
G G G K +A++ + N G+ K+ K++ + G + ++
Sbjct: 1562 GDGREPRTGIKRKLLSASEEDENMGGEDKEKKETKEKSHLSTSESGELGSSLSSESTCGS 1621
Query: 102 KKEGIRRVGRRPDQQLQGE---GKIIDRRPERRPPRER-RFEKPLEEKGEGGEFSVDR-P 156
+ R + G+ K I RP+R+ ++ ++ + +G GG R
Sbjct: 1622 DSDS-ESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHGNGKRNWKTRGTGGRGRWGRWG 1680
Query: 157 IIDRPIRGRGGLG---RGRGG---RGRGMGRGDGFDSRG 189
R RGRGG G RGRGG RGRG GRG SRG
Sbjct: 1681 RWSRGGRGRGGRGRGSRGRGGGGTRGRGRGRGGRGASRG 1719
Score = 37.7 bits (86), Expect = 0.018
Identities = 20/28 (71%), Positives = 20/28 (71%), Gaps = 1/28 (3%)
Query: 339 GDLGRPGRGGRGGRGGRGRGGRPNRGSR 366
G GR GR GR RGGRGRGGR RGSR
Sbjct: 1671 GGRGRWGRWGRWSRGGRGRGGR-GRGSR 1697
Score = 33.5 bits (75), Expect = 0.33
Identities = 18/30 (60%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 338 FGDLGRPGRGGRGGRGGRGRGGRPNRGSRT 367
+G GR RGGRG RGGRGRG R G T
Sbjct: 1676 WGRWGRWSRGGRG-RGGRGRGSRGRGGGGT 1704
Score = 30.8 bits (68), Expect = 2.2
Identities = 20/44 (45%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
Query: 339 GDLGRPGRGGRGGRGGRGRG-GRPNRGSRTDKSSASAPDVDDPE 381
G GR R GRGG G RGRG GR RG+ + A + D E
Sbjct: 1690 GGRGRGSR-GRGGGGTRGRGRGRGGRGASRGATRAKRARIADDE 1732
Score = 28.9 bits (63), Expect = 8.2
Identities = 21/41 (51%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Query: 342 GRPGRGGRG--GRGGRGRGGR-PNRGSRTDKSSASAPDVDD 379
G GRGG G GR GRGRGGR +RG+ K + A D D
Sbjct: 1695 GSRGRGGGGTRGR-GRGRGGRGASRGATRAKRARIADDEFD 1734
>gi|9966841 cell death regulator aven [Homo sapiens]
Length = 362
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/135 (28%), Positives = 55/135 (40%), Gaps = 16/135 (11%)
Query: 126 RRPER-RPPRERRFEKP----LEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
RRP R RP +R E+P +G GG D GR G GRGRG RG G
Sbjct: 13 RRPGRGRPGGDRHSERPGAAAAVARGGGGGGGGDGG-------GRRGRGRGRGFRGARGG 65
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
RG G RG R G+ S +D S + +G DE + + +
Sbjct: 66 RGGGGAPRGSRREPGGWGAGASAPVEDD----SDAETYGEENDEQGNYSKRKIVSNWDRY 121
Query: 241 EEHHPVADTENKENE 255
++ + E+ E++
Sbjct: 122 QDIEKEVNNESGESQ 136
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/42 (57%), Positives = 27/42 (64%), Gaps = 5/42 (11%)
Query: 345 GRGGRGGRGGRGRGGRPNRGSRTDK----SSASAPDVDDPEA 382
GRG RG RGGRG GG P RGSR + + ASAP DD +A
Sbjct: 56 GRGFRGARGGRGGGGAP-RGSRREPGGWGAGASAPVEDDSDA 96
Score = 30.4 bits (67), Expect = 2.8
Identities = 17/34 (50%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 342 GRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAP 375
G G G GGR GRGR GR RG+R + AP
Sbjct: 40 GGGGGGDGGGRRGRGR-GRGFRGARGGRGGGGAP 72
Score = 29.6 bits (65), Expect = 4.8
Identities = 15/32 (46%), Positives = 17/32 (53%)
Query: 343 RPGRGGRGGRGGRGRGGRPNRGSRTDKSSASA 374
R RGGRG R GRGR G R ++A A
Sbjct: 5 RGARGGRGRRPGRGRPGGDRHSERPGAAAAVA 36
>gi|62988361 absent in melanoma 1 [Homo sapiens]
Length = 1723
Score = 41.2 bits (95), Expect = 0.002
Identities = 69/267 (25%), Positives = 96/267 (35%), Gaps = 51/267 (19%)
Query: 16 RFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQ 75
R D +FDDE P A +KK G SAA ++ + G QLR ES
Sbjct: 35 RDDAVFDDEVAPNAASDNASAEKKVKSPRAALDGGVASAASPESKPSPGTKG-QLRGES- 92
Query: 76 KDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRE 135
DR PP+ +K ++ A+ P G P +R P
Sbjct: 93 -DRSKQPPPASSPTKRKGRSRALEAV-----------PAPPASGPRAPAKESPPKRVPDP 140
Query: 136 RRFEK-PLEEKGEGGEFSVDR--PIID-------RPIRGRGGL-----GRGRGGRGRGMG 180
K E GE ++ R P+ +P RG L GR GGR R +G
Sbjct: 141 SPVTKGTAAESGEEAARAIPRELPVKSSSLLPEIKPEHKRGPLPNHFNGRAEGGRSRELG 200
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTE---ET 237
R G SD GLK + G S TV ++T + E +T
Sbjct: 201 RAAG----------APGASDADGLKPRNHFGVGRS----TVTTKVTLPAKPKHVELNLKT 246
Query: 238 PE-----GEEHHPVADTENKENEVEEV 259
P+ G EH+P + +K N ++
Sbjct: 247 PKNLDSLGNEHNPFSQPVHKGNTATKI 273
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 41.2 bits (95), Expect = 0.002
Identities = 72/309 (23%), Positives = 117/309 (37%), Gaps = 53/309 (17%)
Query: 70 LRKESQKDRKNPLPP------SVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKI 123
L ++ +D + PL P V ++T +K+E ++P++ + + I
Sbjct: 1095 LAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEE------KQPEKVISKDLVI 1148
Query: 124 IDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGG---LGRGRGGRGRGMG 180
RP+ RP ++ E L + E D+ RGRG RGR RG G
Sbjct: 1149 ERPRPDSRPAVKK--ESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGG 1206
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
RG RG R G R ++ D + + G ++ ++S E+ +
Sbjct: 1207 RG-----RGGR------GHTRDYPQYRDNKPRAEHIPSGPLRQR----EESETRSESSDF 1251
Query: 241 EEHHPVADTENKENEVE-EVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWK 299
E E + + E+ E + +L + K + ++R + K
Sbjct: 1252 EVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPKREERPEN---------------K 1296
Query: 300 KGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGG---RGGRG 356
K H S + H + + KP + + F G P R GRGG RGGR
Sbjct: 1297 KPVKPHSSFKPDNHVR--IDNRLLEKPYVRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRD 1354
Query: 357 RGGRPNRGS 365
GGRP+R S
Sbjct: 1355 PGGRPSRPS 1363
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 40.4 bits (93), Expect = 0.003
Identities = 51/201 (25%), Positives = 75/201 (37%), Gaps = 31/201 (15%)
Query: 35 ENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQL--------RKESQKDRKNPLPPSV 86
+N + GG G K+ AAA T G+Q RK+ ++ K P
Sbjct: 314 QNPRWGRGGKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKA 373
Query: 87 GVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEEKG 146
K K+G+R RR G+G+ ++P + PR RR +K K
Sbjct: 374 SAAGAKSRGGGD----KKGLREAKRR------GDGR---KKPRWQNPR-RRAQKAPAAKP 419
Query: 147 EGGEFSVDRPIIDRPIRGRGGLGRGRGG---RGRGM-GRGDGFDSRGKREFDRHSGSDRS 202
GG R + + RGG R GG R RG R ++ + D+ G ++
Sbjct: 420 RGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKA 479
Query: 203 GLKHEDKRGG-----SGSHNW 218
RGG SG + W
Sbjct: 480 SAAGTKSRGGGLKSHSGKNLW 500
Score = 38.1 bits (87), Expect = 0.014
Identities = 45/197 (22%), Positives = 70/197 (35%), Gaps = 14/197 (7%)
Query: 38 KKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDR------------KNPLPPS 85
+K A GV G + +AAA + +GK+ R+ K R K+ +
Sbjct: 158 QKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKT 217
Query: 86 VGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEEK 145
G KK P A + R G++P +Q + K R +K L +
Sbjct: 218 RGGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQ 277
Query: 146 GEGGEFSVDRPIIDRPIRGRGGLGRGRGGRG-RGMGRGDGFDSRGKREFDRHSGSDRSGL 204
G+ + + G +GRGGRG + +G + RG ++ R
Sbjct: 278 GQNAALAGAKR-RGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAA 336
Query: 205 KHEDKRGGSGSHNWGTV 221
KRGG G V
Sbjct: 337 AAGTKRGGGGQQKAAVV 353
Score = 34.3 bits (77), Expect = 0.20
Identities = 48/198 (24%), Positives = 67/198 (33%), Gaps = 47/198 (23%)
Query: 43 GGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQ-----KDRKNPL--------------- 82
GGG PG + AA ++ S GK+ ++ K RK P
Sbjct: 589 GGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWA 648
Query: 83 --PPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRRPERRPPRERRFEK 140
S G K+ Q P A E + R+ PR RR
Sbjct: 649 TGATSRGSGGKQPRWQKPAAAGSES------------SAAAAVGQEAEARKKPRRRR--- 693
Query: 141 PLEEKGEGGEFSVDRPIIDRPIRGRGG---LGRGRGGRGRGMGRGDGFDSRGKREFDRHS 197
+ +G+GG+ + + P + RG LG+ RGG G G SRG S
Sbjct: 694 -AKSRGDGGQ---NAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRS 749
Query: 198 GSDRSGLKHEDKRGGSGS 215
G + K GG G+
Sbjct: 750 GKKAAASK---SHGGGGA 764
Score = 32.3 bits (72), Expect = 0.74
Identities = 49/182 (26%), Positives = 65/182 (35%), Gaps = 33/182 (18%)
Query: 33 AAENKKKEAGGGG-------VGGPGAKSAAQ--------AAAQTNSNAAGKQLRKESQKD 77
AA K +G GG G GAKS + AAA + A G R K
Sbjct: 601 AAGVTKSRSGDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQ 660
Query: 78 RKNPLPPSVGVVDKKEETQPPVALKKEG-IRRVGRRPDQQLQGEGKIIDRRPERRPPRER 136
+ P + G E+ A+ +E R+ RR + +G+G P +R
Sbjct: 661 PRWQKPAAAG-----SESSAAAAVGQEAEARKKPRRRRAKSRGDGG--QNAAVGINPWQR 713
Query: 137 RFEKPLEEKGEGGEFSVDRPIIDRPIRGRGG----------LGRGRGGRGRGMGRGDGFD 186
R +KP K GG + R RG GG + GG G RG G
Sbjct: 714 RGKKPRLGKSRGGGGAKSRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAK 773
Query: 187 SR 188
SR
Sbjct: 774 SR 775
Score = 30.4 bits (67), Expect = 2.8
Identities = 48/183 (26%), Positives = 61/183 (33%), Gaps = 30/183 (16%)
Query: 32 KAAENKKKEAGGGGVGGPGAKSAAQAAAQTNS-NAAGKQLRKESQK----DRKNP---LP 83
+A ++ +K AG GG G AAA T S G++ R+ QK K P
Sbjct: 84 EARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQ 143
Query: 84 PSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEG--KIIDRRPERRPPRER----- 136
S K A G++ G Q+ G ++P RR + R
Sbjct: 144 KSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDK 203
Query: 137 ----RFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGG-------RGRGMGRGDGF 185
R K K GG R RP GG RGG R RG G
Sbjct: 204 KGRQREAKSRFGKTRGGRRKKHR----RPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGG 259
Query: 186 DSR 188
SR
Sbjct: 260 KSR 262
>gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]
Length = 217
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/66 (43%), Positives = 32/66 (48%), Gaps = 18/66 (27%)
Query: 128 PERRPPRERRFEKPLEEKG--EGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDGF 185
P + P +R +P EKG GG GRGG G GRGG GRG GRG GF
Sbjct: 148 PYKLLPLQRFLPRPPGEKGPPRGG--------------GRGGRGGGRGGGGRGGGRGGGF 193
Query: 186 DSRGKR 191
RG R
Sbjct: 194 --RGGR 197
Score = 36.2 bits (82), Expect = 0.051
Identities = 59/211 (27%), Positives = 76/211 (36%), Gaps = 36/211 (17%)
Query: 164 GRGGLGRGRGGRGRGMG------RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHN 217
GRGG RG GG G G RG G G G R G + GG G N
Sbjct: 7 GRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGG----GNFRGGGRGGF---GRGGGRGGFN 59
Query: 218 WGTVKDELTDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQN 277
G DQ GE HP D + V + + K + ++N
Sbjct: 60 KGQ--------DQGPPERVVLLGEFLHPCED-----DIVCKCTTDENKVPYFNAPVYLEN 106
Query: 278 KDRAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQ--LE 335
K++ I K +E GQ + + K + + + P + Q L
Sbjct: 107 KEQ------IGKVDE-IFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLP 159
Query: 336 INFGDLGRPGRGGRGGRGGRGRGGRPNRGSR 366
G+ G P GGRGGRGG GRGG G R
Sbjct: 160 RPPGEKGPPRGGGRGGRGG-GRGGGGRGGGR 189
Score = 30.4 bits (67), Expect = 2.8
Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 22/69 (31%)
Query: 131 RPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRG----------MG 180
RPP E+ + G GG RG GG G GRGG RG G
Sbjct: 160 RPPGEKGPPRGGGRGGRGGG------------RGGGGRGGGRGGGFRGGRGGGGGGFRGG 207
Query: 181 RGDGFDSRG 189
RG GF RG
Sbjct: 208 RGGGFRGRG 216
>gi|9506713 nucleolar protein family A, member 1 [Homo sapiens]
Length = 217
Score = 40.4 bits (93), Expect = 0.003
Identities = 29/66 (43%), Positives = 32/66 (48%), Gaps = 18/66 (27%)
Query: 128 PERRPPRERRFEKPLEEKG--EGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDGF 185
P + P +R +P EKG GG GRGG G GRGG GRG GRG GF
Sbjct: 148 PYKLLPLQRFLPRPPGEKGPPRGG--------------GRGGRGGGRGGGGRGGGRGGGF 193
Query: 186 DSRGKR 191
RG R
Sbjct: 194 --RGGR 197
Score = 36.2 bits (82), Expect = 0.051
Identities = 59/211 (27%), Positives = 76/211 (36%), Gaps = 36/211 (17%)
Query: 164 GRGGLGRGRGGRGRGMG------RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHN 217
GRGG RG GG G G RG G G G R G + GG G N
Sbjct: 7 GRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGG----GNFRGGGRGGF---GRGGGRGGFN 59
Query: 218 WGTVKDELTDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQN 277
G DQ GE HP D + V + + K + ++N
Sbjct: 60 KGQ--------DQGPPERVVLLGEFLHPCED-----DIVCKCTTDENKVPYFNAPVYLEN 106
Query: 278 KDRAKVEFNIRKPNEGADGQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQ--LE 335
K++ I K +E GQ + + K + + + P + Q L
Sbjct: 107 KEQ------IGKVDE-IFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLP 159
Query: 336 INFGDLGRPGRGGRGGRGGRGRGGRPNRGSR 366
G+ G P GGRGGRGG GRGG G R
Sbjct: 160 RPPGEKGPPRGGGRGGRGG-GRGGGGRGGGR 189
Score = 30.4 bits (67), Expect = 2.8
Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 22/69 (31%)
Query: 131 RPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRG----------MG 180
RPP E+ + G GG RG GG G GRGG RG G
Sbjct: 160 RPPGEKGPPRGGGRGGRGGG------------RGGGGRGGGRGGGFRGGRGGGGGGFRGG 207
Query: 181 RGDGFDSRG 189
RG GF RG
Sbjct: 208 RGGGFRGRG 216
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 23/144 (15%)
Query: 51 AKSAAQAAAQTNSNAAGKQLRK--ESQKDRKNPLPPSVGVVDKKEETQPPVALKKEG--- 105
A+SA+ +++ ++S+ + ++K +K + PLP G K E +PP + +
Sbjct: 251 ARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPE--RPPSSSSSDSDSD 308
Query: 106 -IRRVG---------------RRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEEKGEGG 149
+ R+ RR +Q + ++ ++ E + R R ++ E+G GG
Sbjct: 309 EVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGG 368
Query: 150 EFSVDRPIIDRPIRGRGGLGRGRG 173
+ D P++ RG GRGRG
Sbjct: 369 SSGDELREDDEPVKKRGRKGRGRG 392
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 40.4 bits (93), Expect = 0.003
Identities = 34/144 (23%), Positives = 65/144 (45%), Gaps = 23/144 (15%)
Query: 51 AKSAAQAAAQTNSNAAGKQLRK--ESQKDRKNPLPPSVGVVDKKEETQPPVALKKEG--- 105
A+SA+ +++ ++S+ + ++K +K + PLP G K E +PP + +
Sbjct: 251 ARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPE--RPPSSSSSDSDSD 308
Query: 106 -IRRVG---------------RRPDQQLQGEGKIIDRRPERRPPRERRFEKPLEEKGEGG 149
+ R+ RR +Q + ++ ++ E + R R ++ E+G GG
Sbjct: 309 EVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSGG 368
Query: 150 EFSVDRPIIDRPIRGRGGLGRGRG 173
+ D P++ RG GRGRG
Sbjct: 369 SSGDELREDDEPVKKRGRKGRGRG 392
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 40.0 bits (92), Expect = 0.004
Identities = 48/218 (22%), Positives = 89/218 (40%), Gaps = 22/218 (10%)
Query: 68 KQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRR 127
+Q R+E ++ + +++K E ++ +R + +Q + E + +RR
Sbjct: 138 RQKRREMAREHSRRERDRLEQLERKRE-------RERKMREQQKEQREQKERERRAEERR 190
Query: 128 PERRPPRE-----RRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGG-RGRGMGR 181
ER RE R + +K + +S P RP R R LG GR + M
Sbjct: 191 KEREARREVSAHHRTMREDYSDKVKASHWSRSPP---RPPRERFELGDGRKPVKEEKMEE 247
Query: 182 GDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGE 241
D + S S+R E SGS + ++E + ++ + +EE+ E E
Sbjct: 248 RDLLS-----DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 302
Query: 242 EHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD 279
E + E N EE E+ +E++ +E + ++
Sbjct: 303 EEEEEEEEETGSNS-EEASEQSAEEVSEEEMSEDEERE 339
Score = 32.7 bits (73), Expect = 0.57
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 15/159 (9%)
Query: 127 RPERRPPRERRFE-----KPL-EEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
R RPPRER FE KP+ EEK E + D I R G G
Sbjct: 221 RSPPRPPRER-FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 279
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
+ + + E S+ + E++ +GS++ + ++ + ++E+
Sbjct: 280 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 339
Query: 241 EEHHPVA--------DTENKENEVEEVKEEGPKEMTLDE 271
E+H + D+ E EEV E P+ L E
Sbjct: 340 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 378
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 40.0 bits (92), Expect = 0.004
Identities = 48/218 (22%), Positives = 89/218 (40%), Gaps = 22/218 (10%)
Query: 68 KQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRR 127
+Q R+E ++ + +++K E ++ +R + +Q + E + +RR
Sbjct: 148 RQKRREMAREHSRRERDRLEQLERKRE-------RERKMREQQKEQREQKERERRAEERR 200
Query: 128 PERRPPRE-----RRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGG-RGRGMGR 181
ER RE R + +K + +S P RP R R LG GR + M
Sbjct: 201 KEREARREVSAHHRTMREDYSDKVKASHWSRSPP---RPPRERFELGDGRKPVKEEKMEE 257
Query: 182 GDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGE 241
D + S S+R E SGS + ++E + ++ + +EE+ E E
Sbjct: 258 RDLLS-----DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 312
Query: 242 EHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD 279
E + E N EE E+ +E++ +E + ++
Sbjct: 313 EEEEEEEEETGSNS-EEASEQSAEEVSEEEMSEDEERE 349
Score = 32.7 bits (73), Expect = 0.57
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 15/159 (9%)
Query: 127 RPERRPPRERRFE-----KPL-EEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
R RPPRER FE KP+ EEK E + D I R G G
Sbjct: 231 RSPPRPPRER-FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 289
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
+ + + E S+ + E++ +GS++ + ++ + ++E+
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Query: 241 EEHHPVA--------DTENKENEVEEVKEEGPKEMTLDE 271
E+H + D+ E EEV E P+ L E
Sbjct: 350 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 388
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 40.0 bits (92), Expect = 0.004
Identities = 48/218 (22%), Positives = 89/218 (40%), Gaps = 22/218 (10%)
Query: 68 KQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRR 127
+Q R+E ++ + +++K E ++ +R + +Q + E + +RR
Sbjct: 139 RQKRREMAREHSRRERDRLEQLERKRE-------RERKMREQQKEQREQKERERRAEERR 191
Query: 128 PERRPPRE-----RRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGG-RGRGMGR 181
ER RE R + +K + +S P RP R R LG GR + M
Sbjct: 192 KEREARREVSAHHRTMREDYSDKVKASHWSRSPP---RPPRERFELGDGRKPVKEEKMEE 248
Query: 182 GDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGE 241
D + S S+R E SGS + ++E + ++ + +EE+ E E
Sbjct: 249 RDLLS-----DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 303
Query: 242 EHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD 279
E + E N EE E+ +E++ +E + ++
Sbjct: 304 EEEEEEEEETGSNS-EEASEQSAEEVSEEEMSEDEERE 340
Score = 32.7 bits (73), Expect = 0.57
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 15/159 (9%)
Query: 127 RPERRPPRERRFE-----KPL-EEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
R RPPRER FE KP+ EEK E + D I R G G
Sbjct: 222 RSPPRPPRER-FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 280
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
+ + + E S+ + E++ +GS++ + ++ + ++E+
Sbjct: 281 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 340
Query: 241 EEHHPVA--------DTENKENEVEEVKEEGPKEMTLDE 271
E+H + D+ E EEV E P+ L E
Sbjct: 341 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 379
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 40.0 bits (92), Expect = 0.004
Identities = 48/218 (22%), Positives = 89/218 (40%), Gaps = 22/218 (10%)
Query: 68 KQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRR 127
+Q R+E ++ + +++K E ++ +R + +Q + E + +RR
Sbjct: 116 RQKRREMAREHSRRERDRLEQLERKRE-------RERKMREQQKEQREQKERERRAEERR 168
Query: 128 PERRPPRE-----RRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGG-RGRGMGR 181
ER RE R + +K + +S P RP R R LG GR + M
Sbjct: 169 KEREARREVSAHHRTMREDYSDKVKASHWSRSPP---RPPRERFELGDGRKPVKEEKMEE 225
Query: 182 GDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGE 241
D + S S+R E SGS + ++E + ++ + +EE+ E E
Sbjct: 226 RDLLS-----DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 280
Query: 242 EHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD 279
E + E N EE E+ +E++ +E + ++
Sbjct: 281 EEEEEEEEETGSNS-EEASEQSAEEVSEEEMSEDEERE 317
Score = 32.7 bits (73), Expect = 0.57
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 15/159 (9%)
Query: 127 RPERRPPRERRFE-----KPL-EEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
R RPPRER FE KP+ EEK E + D I R G G
Sbjct: 199 RSPPRPPRER-FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 257
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
+ + + E S+ + E++ +GS++ + ++ + ++E+
Sbjct: 258 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 317
Query: 241 EEHHPVA--------DTENKENEVEEVKEEGPKEMTLDE 271
E+H + D+ E EEV E P+ L E
Sbjct: 318 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 356
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 40.0 bits (92), Expect = 0.004
Identities = 48/218 (22%), Positives = 89/218 (40%), Gaps = 22/218 (10%)
Query: 68 KQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRR 127
+Q R+E ++ + +++K E ++ +R + +Q + E + +RR
Sbjct: 105 RQKRREMAREHSRRERDRLEQLERKRE-------RERKMREQQKEQREQKERERRAEERR 157
Query: 128 PERRPPRE-----RRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGG-RGRGMGR 181
ER RE R + +K + +S P RP R R LG GR + M
Sbjct: 158 KEREARREVSAHHRTMREDYSDKVKASHWSRSPP---RPPRERFELGDGRKPVKEEKMEE 214
Query: 182 GDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGE 241
D + S S+R E SGS + ++E + ++ + +EE+ E E
Sbjct: 215 RDLLS-----DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 269
Query: 242 EHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD 279
E + E N EE E+ +E++ +E + ++
Sbjct: 270 EEEEEEEEETGSNS-EEASEQSAEEVSEEEMSEDEERE 306
Score = 32.7 bits (73), Expect = 0.57
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 15/159 (9%)
Query: 127 RPERRPPRERRFE-----KPL-EEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
R RPPRER FE KP+ EEK E + D I R G G
Sbjct: 188 RSPPRPPRER-FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 246
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
+ + + E S+ + E++ +GS++ + ++ + ++E+
Sbjct: 247 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 306
Query: 241 EEHHPVA--------DTENKENEVEEVKEEGPKEMTLDE 271
E+H + D+ E EEV E P+ L E
Sbjct: 307 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 345
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 40.0 bits (92), Expect = 0.004
Identities = 48/218 (22%), Positives = 89/218 (40%), Gaps = 22/218 (10%)
Query: 68 KQLRKESQKDRKNPLPPSVGVVDKKEETQPPVALKKEGIRRVGRRPDQQLQGEGKIIDRR 127
+Q R+E ++ + +++K E ++ +R + +Q + E + +RR
Sbjct: 150 RQKRREMAREHSRRERDRLEQLERKRE-------RERKMREQQKEQREQKERERRAEERR 202
Query: 128 PERRPPRE-----RRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGG-RGRGMGR 181
ER RE R + +K + +S P RP R R LG GR + M
Sbjct: 203 KEREARREVSAHHRTMREDYSDKVKASHWSRSPP---RPPRERFELGDGRKPVKEEKMEE 259
Query: 182 GDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGE 241
D + S S+R E SGS + ++E + ++ + +EE+ E E
Sbjct: 260 RDLLS-----DLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEE 314
Query: 242 EHHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKD 279
E + E N EE E+ +E++ +E + ++
Sbjct: 315 EEEEEEEEETGSNS-EEASEQSAEEVSEEEMSEDEERE 351
Score = 32.7 bits (73), Expect = 0.57
Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 15/159 (9%)
Query: 127 RPERRPPRERRFE-----KPL-EEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMG 180
R RPPRER FE KP+ EEK E + D I R G G
Sbjct: 233 RSPPRPPRER-FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE 291
Query: 181 RGDGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEG 240
+ + + E S+ + E++ +GS++ + ++ + ++E+
Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
Query: 241 EEHHPVA--------DTENKENEVEEVKEEGPKEMTLDE 271
E+H + D+ E EEV E P+ L E
Sbjct: 352 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 390
>gi|239744552 PREDICTED: hypothetical protein [Homo sapiens]
Length = 221
Score = 39.3 bits (90), Expect = 0.006
Identities = 45/162 (27%), Positives = 59/162 (36%), Gaps = 38/162 (23%)
Query: 48 GPGAKSAAQAAAQTNSNAAGKQL------RKESQKDRKNPLP------PSVGVVDKKEET 95
GPG AAQA A+ A + R R P+P P+ + +
Sbjct: 48 GPGRVRAAQARARRGGGARERPAEGARGPRAARGGARAAPMPSSAPRGPTEPALRRPSSA 107
Query: 96 QPPVALKKEGIRRVGRRP--------DQQLQGEGKIIDRRPERR----PPRERRFEKPLE 143
+ P+A VGR P + G+ + D RP R PP E+R LE
Sbjct: 108 ERPLAQAPSSSASVGRAPGAMASPSRSSEATGKPRGRDGRPRREEDDVPPEEKRLRLLLE 167
Query: 144 ------EKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRGM 179
+ GE GE D P GR G GG GRG+
Sbjct: 168 GGSAQPQDGEDGE--------DAPRPGRVETGTQTGGDGRGV 201
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 39.3 bits (90), Expect = 0.006
Identities = 63/271 (23%), Positives = 97/271 (35%), Gaps = 52/271 (19%)
Query: 44 GGVGG--PGAKSAAQAAAQTNSNAAGKQLRKESQKDRKN-PLPPSVGVVDKKEETQPPVA 100
GG+ G P ++ Q ++ + Q+ K + P P D+ EE PP A
Sbjct: 1990 GGLRGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSA 2049
Query: 101 LKKEGIRRVGRRPDQQLQG------EGKIIDRRPERRPPRER-RF-----EKPLEEKGEG 148
L G+ P+ Q EGK + R + R+R RF EKPLEE
Sbjct: 2050 LSSSA---PGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQ 2106
Query: 149 GEFSVDRPIIDRPIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSGLKHED 208
G S DR R RGR R +D RE+DRH D
Sbjct: 2107 GRASEDR--------------RRERERGRNWSRERDWDR--PREWDRHRDKD-------- 2142
Query: 209 KRGGSGSHNWGTVKDELTDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKE-----EG 263
S +W ++ + D+ + E + + +E + ++ E
Sbjct: 2143 -----SSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRER 2197
Query: 264 PKEMTLDEWKAIQNKDRAKVEFNIRKPNEGA 294
++ D + KDR+K + + R P A
Sbjct: 2198 DRDKARDRERGRDRKDRSKSKESARDPKPEA 2228
>gi|169217514 PREDICTED: Inactive ubiquitin carboxyl-terminal
hydrolase 17-like protein 7 [Homo sapiens]
Length = 530
Score = 38.9 bits (89), Expect = 0.008
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 35/178 (19%)
Query: 190 KREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGEEHHPVADT 249
K E++RHS S G E + G+ + + EL + + + PE +EH
Sbjct: 375 KSEWERHSESVSRG--REPRALGAEDTDRPATQGELK---RDHPCLQVPELDEH------ 423
Query: 250 ENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWKKG-FVLHKS- 307
+ E +E TLD WK Q +++ K EFN+RK +G V+H+S
Sbjct: 424 ---------LVERATQESTLDHWKFPQKQNKTKPEFNVRK----VEGTLPPNVLVIHQSK 470
Query: 308 -----KSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGR 360
K+ + S+++ KP T Q +N G L R +G R
Sbjct: 471 YKCGMKNHHPEQQSSLLNLSSTKP----TDQESMNTGTLASLQGSTRRSKGNNKHSKR 524
>gi|169163728 PREDICTED: hypothetical protein [Homo sapiens]
Length = 237
Score = 38.9 bits (89), Expect = 0.008
Identities = 32/97 (32%), Positives = 37/97 (38%), Gaps = 8/97 (8%)
Query: 119 GEGKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIDRPIRGRGGLGRGRGGRGRG 178
GE + RRP R PP RR P G P++ R GR G RGG G
Sbjct: 105 GEERSQPRRPRRPPPAPRR---PRPAPGRRKSLYEAAPLLTREKGGRSGRRGDRGGSGWS 161
Query: 179 MGR-----GDGFDSRGKREFDRHSGSDRSGLKHEDKR 210
G G G S G F S SG + E +R
Sbjct: 162 HGHTARVGGTGDSSAGLTTFPGSSRGGFSGREEEPRR 198
>gi|239749360 PREDICTED: Inactive ubiquitin carboxyl-terminal
hydrolase 17-like protein 7 [Homo sapiens]
Length = 530
Score = 38.9 bits (89), Expect = 0.008
Identities = 45/178 (25%), Positives = 71/178 (39%), Gaps = 35/178 (19%)
Query: 190 KREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTDLDQSNVTEETPEGEEHHPVADT 249
K E++RHS S G E + G+ + + EL + + + PE +EH
Sbjct: 375 KSEWERHSESVSRG--REPRALGAEDTDRPATQGELK---RDHPCLQVPELDEH------ 423
Query: 250 ENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWKKG-FVLHKS- 307
+ E +E TLD WK Q +++ K EFN+RK +G V+H+S
Sbjct: 424 ---------LVERATQESTLDHWKFPQKQNKTKPEFNVRK----VEGTLPPNVLVIHQSK 470
Query: 308 -----KSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGR 360
K+ + S+++ KP T Q +N G L R +G R
Sbjct: 471 YKCGMKNHHPEQQSSLLNLSSTKP----TDQESMNTGTLASLQGSTRRSKGNNKHSKR 524
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,631,644
Number of Sequences: 37866
Number of extensions: 1087031
Number of successful extensions: 10033
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 172
Number of HSP's successfully gapped in prelim test: 378
Number of HSP's that attempted gapping in prelim test: 7407
Number of HSP's gapped (non-prelim): 2384
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.