Search of human proteins with 6631095

Search of human proteins with 6631095

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6631095 minichromosome maintenance complex component 3 [Homo
sapiens]
         (808 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6631095 minichromosome maintenance complex component 3 [Homo ...  1584   0.0  
gi|33469968 minichromosome maintenance complex component 7 isofo...   318   1e-86
gi|33356547 minichromosome maintenance complex component 2 [Homo...   316   5e-86
gi|33469922 minichromosome maintenance complex component 7 isofo...   304   2e-82
gi|33469919 minichromosome maintenance complex component 4 [Homo...   297   2e-80
gi|33469917 minichromosome maintenance complex component 4 [Homo...   297   2e-80
gi|7427519 minichromosome maintenance complex component 6 [Homo ...   297   2e-80
gi|23510448 minichromosome maintenance complex component 5 [Homo...   289   8e-78
gi|19923727 minichromosome maintenance complex component 8 isofo...   239   7e-63
gi|33469924 minichromosome maintenance complex component 8 isofo...   236   5e-62
gi|23397546 minichromosome maintenance complex component 9 [Homo...   103   5e-22
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]                       50   8e-06
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]                       50   8e-06
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       49   2e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    48   3e-05
gi|221219020 NYD-SP11 protein [Homo sapiens]                           47   5e-05
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     47   9e-05
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    46   1e-04
gi|148612801 KIAA1009 protein [Homo sapiens]                           46   2e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    45   3e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    45   3e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    45   3e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    45   3e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          45   3e-04
gi|150378539 piccolo isoform 1 [Homo sapiens]                          45   3e-04
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]         44   6e-04
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]                       44   8e-04
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]                        44   8e-04
gi|4508005 tripartite motif-containing 26 [Homo sapiens]               44   8e-04
gi|55741661 hypothetical protein LOC57653 [Homo sapiens]               43   0.001

>gi|6631095 minichromosome maintenance complex component 3 [Homo
           sapiens]
          Length = 808

 Score = 1584 bits (4102), Expect = 0.0
 Identities = 808/808 (100%), Positives = 808/808 (100%)

Query: 1   MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEK 60
           MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEK
Sbjct: 1   MAGTVVLDDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEK 60

Query: 61  RANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCF 120
           RANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCF
Sbjct: 61  RANRLLNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCF 120

Query: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180
           LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180

Query: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240
           NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT
Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240

Query: 241 YRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLA 300
           YRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLA
Sbjct: 241 YRCLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLA 300

Query: 301 KSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLC 360
           KSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLC
Sbjct: 301 KSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLC 360

Query: 361 TAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRT 420
           TAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRT
Sbjct: 361 TAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRT 420

Query: 421 AIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFD 480
           AIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFD
Sbjct: 421 AIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFD 480

Query: 481 LLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQ 540
           LLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQ
Sbjct: 481 LLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQ 540

Query: 541 DTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQ 600
           DTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQ
Sbjct: 541 DTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQ 600

Query: 601 DSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEK 660
           DSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEK
Sbjct: 601 DSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEK 660

Query: 661 EKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQV 720
           EKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQV
Sbjct: 661 EKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQV 720

Query: 721 HTPKTADSQETKESQKVELSESRLKAFKVALLDVFREAHAQSIGMNRLTESINRDSEEPF 780
           HTPKTADSQETKESQKVELSESRLKAFKVALLDVFREAHAQSIGMNRLTESINRDSEEPF
Sbjct: 721 HTPKTADSQETKESQKVELSESRLKAFKVALLDVFREAHAQSIGMNRLTESINRDSEEPF 780

Query: 781 SSVEIQAALSKMQDDNQVMVSEGIIFLI 808
           SSVEIQAALSKMQDDNQVMVSEGIIFLI
Sbjct: 781 SSVEIQAALSKMQDDNQVMVSEGIIFLI 808


>gi|33469968 minichromosome maintenance complex component 7 isoform
           1 [Homo sapiens]
          Length = 719

 Score =  318 bits (815), Expect = 1e-86
 Identities = 221/629 (35%), Positives = 333/629 (52%), Gaps = 75/629 (11%)

Query: 31  IYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKD--FVASID 88
           ++   V+EL+   + R +VN +            +L+   E  +  ++  +D   V S  
Sbjct: 76  LFADAVQELLPQYKEREVVNKD------------VLDVYIEHRLMMEQRSRDPGMVRSPQ 123

Query: 89  ATY-AKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHY 147
             Y A+    F +  +G   +K    R + +  +  +V V GIVT+ S V+PK+V + + 
Sbjct: 124 NQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYT 183

Query: 148 CPATKKTIERRYSDLT--TLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMP 205
           C        +     T   L+  PS      +      L+T    S +   Q + +QE  
Sbjct: 184 CDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRG--SRFIKFQEMKMQEHS 241

Query: 206 EKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGT----FRTVLI 261
           ++ P G +PRS+ V+++ +    A+PGD V V G +  LP  + G+          T L 
Sbjct: 242 DQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQVVQGLLSETYLE 299

Query: 262 ACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLL 321
           A  + +M+K       A ++ + ++  +   +D +++LA S+AP I+GH+ VKKA+L LL
Sbjct: 300 AHRIVKMNKSEDDESGAGELTR-EELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLL 358

Query: 322 LGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAA 381
           +GGV++    G  IRG+INI L+GDP VAKSQLL Y+   APR+  TTGRGSSGVGLTAA
Sbjct: 359 VGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAA 417

Query: 382 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHAR 441
           V  D  +GE  LE GA+VLAD+GV CIDEFDKM++ DRTAIHEVMEQ  ++IAKAGI   
Sbjct: 418 VLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTT 477

Query: 442 LNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHV 501
           LNARCS+LAAANP YGRY+  ++  +NI L  +LLSRFDLL+++ D+ D + D  ++ H+
Sbjct: 478 LNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI 537

Query: 502 LRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEK 561
             +H                              Q  +Q    +E  D  L         
Sbjct: 538 TYVH------------------------------QHSRQPPSQFEPLDMKL--------- 558

Query: 562 MVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETL 621
                 M++YI + +  +P++ +  A YI   Y  +R +   S D   TS   ARTL  +
Sbjct: 559 ------MRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYTS---ARTLLAI 609

Query: 622 IRLATAHAKARMSKTVDLQDAEEAVELVQ 650
           +RL+TA A+ RM   V+ +D  EA+ L++
Sbjct: 610 LRLSTALARLRMVDVVEKEDVNEAIRLME 638


>gi|33356547 minichromosome maintenance complex component 2 [Homo
           sapiens]
          Length = 904

 Score =  316 bits (810), Expect = 5e-86
 Identities = 217/644 (33%), Positives = 339/644 (52%), Gaps = 42/644 (6%)

Query: 10  VELREAQRDYLDFLDDEEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNA 69
           +E+    +++L    D     +++ ++ ++  +N+  L+VN  DL  +    A  L    
Sbjct: 193 LEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAP 252

Query: 70  FEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEG 129
            E L  F  A  + V ++   Y +     +V +      + +  R+L    L+ ++   G
Sbjct: 253 AELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEEL--RSLRQLHLNQLIRTSG 310

Query: 130 IVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLETEYG 189
           +VT C+ V P++    + C      +          V  P S     + +   P E    
Sbjct: 311 VVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVK-PGSC---PECQSAGPFEVNME 366

Query: 190 LSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKG 249
            ++Y+++Q I IQE P K  AG+LPRS D IL  DLVD  KPGD +++ G Y        
Sbjct: 367 ETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSL 426

Query: 250 GYTSG--TFRTVLIACNV-KQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPS 306
              +G   F TV++A +V K+ +K A    + ED+  I   SK   + I +++  S+APS
Sbjct: 427 NTANGFPVFATVILANHVAKKDNKVAVGELTDEDVKMITSLSK--DQQIGEKIFASIAPS 484

Query: 307 IHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAI 366
           I+GH+ +K+ +   L GG  ++      +RGDIN+LL GDP  AKSQ L+Y+   + RAI
Sbjct: 485 IYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYIEKVSSRAI 544

Query: 367 PTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVM 426
            TTG+G+S VGLTA V     + E  LEAGA+VLADRGV  IDEFDKM+D DRT+IHE M
Sbjct: 545 FTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAM 604

Query: 427 EQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIML 486
           EQ  ++I+KAGI   L ARC+V+AAANP+ GRYD   T  EN+ L + ++SRFD+L ++ 
Sbjct: 605 EQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVVR 664

Query: 487 DQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYE 546
           D +DP QD  ++  V+  H    P  ++ + +  GSA +      PN             
Sbjct: 665 DTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAM---PN------------- 708

Query: 547 KHDNLLHGTKKKKEKMVSAAFMKKYIHVAK-IIKPVLTQESATYIAEEYSRLRSQDSMSS 605
                 +G +   +++     +KKYI  AK  + P L Q     +A+ YS LR ++SM++
Sbjct: 709 -----TYGVEPLPQEV-----LKKYIIYAKERVHPKLNQMDQDKVAKMYSDLR-KESMAT 757

Query: 606 DTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELV 649
            +    P+T R +E++IR+A AHA+  +   V   D   A+ ++
Sbjct: 758 GSI---PITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 798


>gi|33469922 minichromosome maintenance complex component 7 isoform
           2 [Homo sapiens]
          Length = 543

 Score =  304 bits (778), Expect = 2e-82
 Identities = 185/458 (40%), Positives = 266/458 (58%), Gaps = 56/458 (12%)

Query: 197 QTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGT- 255
           Q + +QE  ++ P G +PRS+ V+++ +    A+PGD V V G +  LP  + G+     
Sbjct: 57  QEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQVVQ 114

Query: 256 ---FRTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDY 312
                T L A  + +M+K       A ++ + ++  +   +D +++LA S+AP I+GH+ 
Sbjct: 115 GLLSETYLEAHRIVKMNKSEDDESGAGELTR-EELRQIAEEDFYEKLAASIAPEIYGHED 173

Query: 313 VKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRG 372
           VKKA+L LL+GGV++    G  IRG+INI L+GDP VAKSQLL Y+   APR+  TTGRG
Sbjct: 174 VKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRG 232

Query: 373 SSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVT 432
           SSGVGLTAAV  D  +GE  LE GA+VLAD+GV CIDEFDKM++ DRTAIHEVMEQ  ++
Sbjct: 233 SSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTIS 292

Query: 433 IAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPE 492
           IAKAGI   LNARCS+LAAANP YGRY+  ++  +NI L  +LLSRFDLL+++ D+ D +
Sbjct: 293 IAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRD 352

Query: 493 QDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLL 552
            D  ++ H+  +H                              Q  +Q    +E  D  L
Sbjct: 353 NDLRLAQHITYVH------------------------------QHSRQPPSQFEPLDMKL 382

Query: 553 HGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSP 612
                          M++YI + +  +P++ +  A YI   Y  +R +   S D   TS 
Sbjct: 383 ---------------MRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYTS- 426

Query: 613 VTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 650
             ARTL  ++RL+TA A+ RM   V+ +D  EA+ L++
Sbjct: 427 --ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 462


>gi|33469919 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score =  297 bits (761), Expect = 2e-80
 Identities = 219/656 (33%), Positives = 327/656 (49%), Gaps = 81/656 (12%)

Query: 16  QRDYLDFLD----DEEDQGI------YQSKVRELISDNQYRLIVNVNDLRRKNEKRANRL 65
           QR    F+D    +EE+ GI      Y  ++ E+    +  L VN   ++  ++    +L
Sbjct: 167 QRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQL 226

Query: 66  LNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVV 125
           ++   E +  F  A+ +        Y     E  + +      K  + R L    +  ++
Sbjct: 227 ISYPQEVIPTFDMAVNEIFFD---RYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLI 283

Query: 126 CVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLE 185
            + G+V + S + P++  +   C     T   R       +A PS      +    + + 
Sbjct: 284 TISGMVIRTSQLIPEMQEAFFQCQVCAHTT--RVEMDRGRIAEPSVC---GRCHTTHSMA 338

Query: 186 TEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLP 245
             +  S++ D Q I +QE PE  PAGQ P +V +   +DLVDK +PGDRV V G YR +P
Sbjct: 339 LIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVP 398

Query: 246 GKKGGYTSGTFRTVLIACNVKQMSK-DAQPSFSAEDIAKIKKFSK---------TRSKDI 295
            +     S          +V    K DA+     ++ A+ K FS+         +R  DI
Sbjct: 399 IRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDI 458

Query: 296 FDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSH--IRGDINILLIGDPSVAKSQ 353
           +++LA +LAPSI+ H+ +KK IL  L GG  +D  +      R +INILL GDP  +KSQ
Sbjct: 459 YERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQ 518

Query: 354 LLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDK 413
           LL+YV    PR   T+G+GSS VGLTA V  D ET +  L+ GA+VL+D G+ CIDEFDK
Sbjct: 519 LLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDK 578

Query: 414 MSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQD 473
           M++  R+ +HEVMEQ  ++IAKAGI  +LNAR SVLAAANP+  +++  KT +ENI L  
Sbjct: 579 MNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPH 638

Query: 474 SLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPN 533
           +LLSRFDL+F++LD  D   DR ++ H++ ++                            
Sbjct: 639 TLLSRFDLIFLLLDPQDEAYDRRLAHHLVALY---------------------------- 670

Query: 534 FSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVA-KIIKPVLTQESATYIAE 592
           +  E+Q +                  E+++  A +K YI  A   I P L++E++  + E
Sbjct: 671 YQSEEQAE------------------EELLDMAVLKDYIAYAHSTIMPRLSEEASQALIE 712

Query: 593 EYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVEL 648
            Y  +R   S S       P   R LE+LIRLA AHAK R+S  V+  D EEA  L
Sbjct: 713 AYVDMRKIGS-SRGMVSAYP---RQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRL 764


>gi|33469917 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score =  297 bits (761), Expect = 2e-80
 Identities = 219/656 (33%), Positives = 327/656 (49%), Gaps = 81/656 (12%)

Query: 16  QRDYLDFLD----DEEDQGI------YQSKVRELISDNQYRLIVNVNDLRRKNEKRANRL 65
           QR    F+D    +EE+ GI      Y  ++ E+    +  L VN   ++  ++    +L
Sbjct: 167 QRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQL 226

Query: 66  LNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVV 125
           ++   E +  F  A+ +        Y     E  + +      K  + R L    +  ++
Sbjct: 227 ISYPQEVIPTFDMAVNEIFFD---RYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLI 283

Query: 126 CVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLE 185
            + G+V + S + P++  +   C     T   R       +A PS      +    + + 
Sbjct: 284 TISGMVIRTSQLIPEMQEAFFQCQVCAHTT--RVEMDRGRIAEPSVC---GRCHTTHSMA 338

Query: 186 TEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLP 245
             +  S++ D Q I +QE PE  PAGQ P +V +   +DLVDK +PGDRV V G YR +P
Sbjct: 339 LIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVP 398

Query: 246 GKKGGYTSGTFRTVLIACNVKQMSK-DAQPSFSAEDIAKIKKFSK---------TRSKDI 295
            +     S          +V    K DA+     ++ A+ K FS+         +R  DI
Sbjct: 399 IRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDI 458

Query: 296 FDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSH--IRGDINILLIGDPSVAKSQ 353
           +++LA +LAPSI+ H+ +KK IL  L GG  +D  +      R +INILL GDP  +KSQ
Sbjct: 459 YERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQ 518

Query: 354 LLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDK 413
           LL+YV    PR   T+G+GSS VGLTA V  D ET +  L+ GA+VL+D G+ CIDEFDK
Sbjct: 519 LLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDK 578

Query: 414 MSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQD 473
           M++  R+ +HEVMEQ  ++IAKAGI  +LNAR SVLAAANP+  +++  KT +ENI L  
Sbjct: 579 MNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPH 638

Query: 474 SLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPN 533
           +LLSRFDL+F++LD  D   DR ++ H++ ++                            
Sbjct: 639 TLLSRFDLIFLLLDPQDEAYDRRLAHHLVALY---------------------------- 670

Query: 534 FSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVA-KIIKPVLTQESATYIAE 592
           +  E+Q +                  E+++  A +K YI  A   I P L++E++  + E
Sbjct: 671 YQSEEQAE------------------EELLDMAVLKDYIAYAHSTIMPRLSEEASQALIE 712

Query: 593 EYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVEL 648
            Y  +R   S S       P   R LE+LIRLA AHAK R+S  V+  D EEA  L
Sbjct: 713 AYVDMRKIGS-SRGMVSAYP---RQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRL 764


>gi|7427519 minichromosome maintenance complex component 6 [Homo
           sapiens]
          Length = 821

 Score =  297 bits (761), Expect = 2e-80
 Identities = 219/724 (30%), Positives = 353/724 (48%), Gaps = 112/724 (15%)

Query: 9   DVELREAQRDYLDFLDD---EEDQGIYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRL 65
           D    + Q+ +LDFL++    + +  Y     ELI   +  L+V+  DL + N++ +  +
Sbjct: 20  DEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTI 79

Query: 66  LNNAFEELVAFQRALKDFVASIDATYAKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVV 125
               +       RALK FV   D       ++FYV  +    ++H   R LTS  +  + 
Sbjct: 80  QEEFYRVYPYLCRALKTFVK--DRKEIPLAKDFYVAFQ-DLPTRH-KIRELTSSRIGLLT 135

Query: 126 CVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPLE 185
            + G V +   V P++V     C   +  I  R  +       P+    P        L 
Sbjct: 136 RISGQVVRTHPVHPELVSGTFLCLDCQTVI--RDVEQQFKYTQPNICRNPVCANRRRFL- 192

Query: 186 TEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLP 245
            +   S + D Q + IQE   + P G +PRS++VIL  + V+ A+ GD+    GT   +P
Sbjct: 193 LDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVP 252

Query: 246 -------------------GKKGGYTSG------------TFRTVLIACNV--------- 265
                              G  G  T G            ++R V +AC V         
Sbjct: 253 DVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGG 312

Query: 266 KQMSKDAQPSFSAEDIAKIKKFSK----TRSKDIFDQLAKSLAPSIHGHDYVKKAILCLL 321
           K++  + Q + S ++   +K++ K    ++ K+++  L  SL P+IHG+D VK+ +L +L
Sbjct: 313 KELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLML 372

Query: 322 LGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAA 381
            GGV +    G+ +RGDIN+ ++GDPS AKSQ L++V   +PRA+ T+G+ SS  GLTAA
Sbjct: 373 FGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAA 432

Query: 382 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHAR 441
           V  D+E+ E  +EAGA++LAD GV CIDEFDKM   D+ AIHE MEQ  ++I KAG+ A 
Sbjct: 433 VVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKAT 492

Query: 442 LNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHV 501
           LNAR S+LAAANP+ G YD+ K+  +NI L   ++SRFDL FI++D+ +   D  I+  +
Sbjct: 493 LNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRI 552

Query: 502 LRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEK 561
           + +H                             S+ ++   ++Y   D            
Sbjct: 553 VDLH-----------------------------SRIEESIDRVYSLDD------------ 571

Query: 562 MVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETL 621
                 +++Y+  A+  KP +++ES  +I E+Y  LR +D  S  T  +  +T R LE++
Sbjct: 572 ------IRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDG-SGVTKSSWRITVRQLESM 624

Query: 622 IRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKS 681
           IRL+ A A+      V  +  +EA  L+     K ++  E      + D +  ++EE + 
Sbjct: 625 IRLSEAMARMHCCDEVQPKHVKEAFRLLN----KSIIRVE------TPDVNLDQEEEIQM 674

Query: 682 QEDQ 685
           + D+
Sbjct: 675 EVDE 678


>gi|23510448 minichromosome maintenance complex component 5 [Homo
           sapiens]
          Length = 734

 Score =  289 bits (739), Expect = 8e-78
 Identities = 216/687 (31%), Positives = 333/687 (48%), Gaps = 87/687 (12%)

Query: 32  YQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASIDATY 91
           Y+ +++   +  +Y + V + DL   +E  A+ L     E L   + A K+    +    
Sbjct: 55  YRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPR 114

Query: 92  AKQYE---EFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHYC 148
               E   +  V L+       +  R+L S  +S +V + GI+   S VR K  R    C
Sbjct: 115 PSGEEVLQDIQVMLKSDASPSSI--RSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQC 172

Query: 149 PATKKTIERRYSDLTTLVAFPSSSVY--PTKDEENNPLETEYGLSVY---------KDHQ 197
            + + T       LT +   P    Y  P K   +     +  L  Y          D Q
Sbjct: 173 RSCRNT-------LTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQ 225

Query: 198 TITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRC----LPGKKG---- 249
           T+ +QE+P+  P G++PR + +  D  L DK  PG+RV ++G Y      L   +G    
Sbjct: 226 TLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRV 285

Query: 250 --GYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSI 307
             G  S   R + I  +     +    + S ++  + ++ +     ++++ ++KS+APSI
Sbjct: 286 GVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAAL--PNVYEVISKSIAPSI 343

Query: 308 HGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIP 367
            G   +KKAI CLL GG  + L +G   RGDIN+L++GDP  AKSQLL++V   +P  + 
Sbjct: 344 FGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVY 403

Query: 368 TTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVME 427
           T+G+GSS  GLTA+V  D  +    +E GAMVLAD GVVCIDEFDKM + DR AIHE ME
Sbjct: 404 TSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAME 463

Query: 428 QGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLD 487
           Q  ++IAKAGI   LN+RCSVLAAAN V+GR+D+ K   +NI    ++LSRFD++FI+ D
Sbjct: 464 QQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGE-DNIDFMPTILSRFDMIFIVKD 522

Query: 488 QMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEK 547
           + + E+D  ++ HV+ +H           A+    AV                       
Sbjct: 523 EHNEERDVMLAKHVITLH---------VSALTQTQAV----------------------- 550

Query: 548 HDNLLHGTKKKKEKMVSAAFMKKYIHVAKI-IKPVLTQESATYIAEEYSRLRS---QDSM 603
                       E  +  A +KK+I   ++   P L+ E+A  +   Y  +RS   Q   
Sbjct: 551 ------------EGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHER 598

Query: 604 SSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKK 663
            SD   + P+T R LE ++R+A A +K ++       D EEA+ L Q +     L     
Sbjct: 599 DSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAAL---SG 655

Query: 664 RKKRSEDESETEDEEEKSQEDQEQKRK 690
                E  +  ED+E  S+ +++ KR+
Sbjct: 656 TLSGVEGFTSQEDQEMLSRIEKQLKRR 682


>gi|19923727 minichromosome maintenance complex component 8 isoform
           1 [Homo sapiens]
          Length = 840

 Score =  239 bits (610), Expect = 7e-63
 Identities = 172/547 (31%), Positives = 276/547 (50%), Gaps = 37/547 (6%)

Query: 125 VCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPL 184
           + + G V + S ++P   +    C A  +       D     + P+    P     +   
Sbjct: 219 IALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPD--GKYSLPTKCPVPVCRGRSFTA 276

Query: 185 ETEYGLSVYKDHQTITIQEM--PEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYR 242
                L+V  D Q+I IQE+   ++  AG++PR+++  L  DLVD   PGD V + G  +
Sbjct: 277 LRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVK 336

Query: 243 CLPGKKGGYTSGTFRTVLIACNVKQMSKD-AQPSFSAEDIAKIKKFSKTRSKDI------ 295
               ++G          L+      +S    Q + S+ED  K     +   KD+      
Sbjct: 337 VSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEI 396

Query: 296 ------FDQLAKSLAPSIHGHDYVKKAILCLLLGGVER--DLENGSHIRGDINILLIGDP 347
                 F  +  SL P I GH+ VK  +   L GG ++  D +N   IRGD +IL++GDP
Sbjct: 397 QAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDP 456

Query: 348 SVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVC 407
            + KSQ+L+     APR +   G  ++  GLT  ++ D  +G+  LEAGA+VL D+G+  
Sbjct: 457 GLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICG 516

Query: 408 IDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPME 467
           IDEFDKM +  + A+ E MEQ  +++AKAG+   L AR S++AAANPV G Y++ KT  E
Sbjct: 517 IDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSE 575

Query: 468 NIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSA-VDI 526
           N+ +  +LLSRFDL+FI+LD  +   D  +S+HV+ +        + G    + SA V  
Sbjct: 576 NLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAI--------RAGKQRTISSATVAR 627

Query: 527 LATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAK-IIKPVLTQE 585
           + + D N S  +    +   +   ++ G   +    +    ++KYI  A+  + P L+ E
Sbjct: 628 MNSQDSNTSVLEVVSEKPLSERLKVVPG---ETIDPIPHQLLRKYIGYARQYVYPRLSTE 684

Query: 586 SATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEA 645
           +A  + + Y  LR Q    S    +SP+T R LE+LIRL  A A+  + +    +DAE+ 
Sbjct: 685 AARVLQDFYLELRKQ----SQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDI 740

Query: 646 VELVQYA 652
           VE+++Y+
Sbjct: 741 VEIMKYS 747


>gi|33469924 minichromosome maintenance complex component 8 isoform
           2 [Homo sapiens]
          Length = 824

 Score =  236 bits (603), Expect = 5e-62
 Identities = 169/542 (31%), Positives = 278/542 (51%), Gaps = 43/542 (7%)

Query: 125 VCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEENNPL 184
           + + G V + S ++P   +    C A  +       D     + P+    P     +   
Sbjct: 219 IALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPD--GKYSLPTKCPVPVCRGRSFTA 276

Query: 185 ETEYGLSVYKDHQTITIQEM--PEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYR 242
                L+V  D Q+I IQE+   ++  AG++PR+++  L  DLVD   PGD V + G  +
Sbjct: 277 LRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVK 336

Query: 243 CLPGKKGGYTSGTFRTVLIACNVKQMSKDAQPS--------FSAEDIAKIKKFSKTRSKD 294
               ++    S +           Q +K ++          FS +D+  I++      ++
Sbjct: 337 VSNAEEANSISNS---------KGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQA--EEN 385

Query: 295 IFDQLAKSLAPSIHGHDYVKKAILCLLLGGVER--DLENGSHIRGDINILLIGDPSVAKS 352
           +F  +  SL P I GH+ VK  +   L GG ++  D +N   IRGD +IL++GDP + KS
Sbjct: 386 LFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKS 445

Query: 353 QLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFD 412
           Q+L+     APR +   G  ++  GLT  ++ D  +G+  LEAGA+VL D+G+  IDEFD
Sbjct: 446 QMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFD 505

Query: 413 KMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQ 472
           KM +  + A+ E MEQ  +++AKAG+   L AR S++AAANPV G Y++ KT  EN+ + 
Sbjct: 506 KMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMG 564

Query: 473 DSLLSRFDLLFIMLDQMDPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSA-VDILATDD 531
            +LLSRFDL+FI+LD  +   D  +S+HV+ +        + G    + SA V  + + D
Sbjct: 565 SALLSRFDLVFILLDTPNEHHDHLLSEHVIAI--------RAGKQRTISSATVARMNSQD 616

Query: 532 PNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAK-IIKPVLTQESATYI 590
            N S  +    +   +   ++ G   +    +    ++KYI  A+  + P L+ E+A  +
Sbjct: 617 SNTSVLEVVSEKPLSERLKVVPG---ETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVL 673

Query: 591 AEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQ 650
            + Y  LR Q    S    +SP+T R LE+LIRL  A A+  + +    +DAE+ VE+++
Sbjct: 674 QDFYLELRKQ----SQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMK 729

Query: 651 YA 652
           Y+
Sbjct: 730 YS 731


>gi|23397546 minichromosome maintenance complex component 9 [Homo
           sapiens]
          Length = 391

 Score =  103 bits (258), Expect = 5e-22
 Identities = 100/366 (27%), Positives = 160/366 (43%), Gaps = 32/366 (8%)

Query: 36  VRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKDFVASI-------D 88
           ++E   D  Y ++VN   L   N +          E L  F  AL+    +I       +
Sbjct: 29  LKERDEDAHYPVVVNAMTLFETNMEIGEYFNMFPSEVLTIFDSALRRSALTILQSLSQPE 88

Query: 89  ATYAKQYEEFYVGLEG-----SFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVR 143
           A   KQ    +  + G         +H+        FLS    V G V + SLV+     
Sbjct: 89  AVSMKQ--NLHARISGLPVCPELVREHIPKTKDVGHFLS----VTGTVIRTSLVKVLEFE 142

Query: 144 SVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDE-ENNPLETEYGLSVY----KDHQT 198
             + C   K     + +D      F   S  P+ +  +++      GLS      +D+Q 
Sbjct: 143 RDYMCNKCKHVFVIK-ADFEQYYTFCRPSSCPSLESCDSSKFTCLSGLSSSPTRCRDYQE 201

Query: 199 ITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTY--RCLPGKKGGYTSGTF 256
           I IQE  ++   G +PRS+ VIL+DDLVD  K GD + + G    R  P ++        
Sbjct: 202 IKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVMQRWKPFQQD--VRCEV 259

Query: 257 RTVLIACNVKQMSKDAQPSFSAEDIAK-IKKFSKTRSKDIF---DQLAKSLAPSIHGHDY 312
             VL A  ++  ++ +      E++ K  + F +    D F   + +  SL P + G   
Sbjct: 260 EIVLKANYIQVNNEQSSGIIMDEEVQKEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYL 319

Query: 313 VKKAILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRG 372
           VK A+  +L GG++R    G+ +RG+ ++LL+GDP   KSQ L+Y     PR++ TTG G
Sbjct: 320 VKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIG 379

Query: 373 SSGVGL 378
           S+  G+
Sbjct: 380 STSAGI 385


>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
          Length = 558

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 68/282 (24%), Positives = 116/282 (41%), Gaps = 31/282 (10%)

Query: 490 DPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHD 549
           D E++ E  +   R       GE+ G  +   +  + L  D P F +E+ +D +I  K D
Sbjct: 181 DKEKEEEEEEKPKRGSIGENQGEEKGTKVQ--AKREKLQEDKPTFKKEEIKDEKI--KKD 236

Query: 550 NLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTAR 609
                 K+ KE++ S    KK     K            +    +SR   + S+ +  A 
Sbjct: 237 ------KEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAE 290

Query: 610 TSPVT--ARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFK----KVLEKEKK 663
            +P     + LE L R           K    Q  E A+EL +    +    KVLE+E++
Sbjct: 291 GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ-EAALELEELKKKREERRKVLEEEEQ 349

Query: 664 RKKRSEDESETEDEEEKSQEDQEQKRKRRKT---RQPDAKDGDSYDPYDFS--------- 711
           R+K+ E + +  +EEEK +  +E +R+R +    RQ   +DG S D   F          
Sbjct: 350 RRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSL 409

Query: 712 --DTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVAL 751
             +   E       K++  + T ++  V   +SRL+ +  A+
Sbjct: 410 KIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAI 451



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 36/174 (20%), Positives = 72/174 (41%), Gaps = 12/174 (6%)

Query: 584 QESATYIAEEYSRLRSQDSMSSDTARTSPVTARTL---ETLIRLATAHAKARMSKTVDLQ 640
           +ES   + ++   + +Q+S+  + A+T+    +     E       A  + R  K   LQ
Sbjct: 50  EESLGQVTDQVE-VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR--LQ 106

Query: 641 DAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQ------KRKRRKT 694
           +A E  +          L    +R +    E+ET ++EEKS+  QE+      +   +  
Sbjct: 107 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSY 166

Query: 695 RQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFK 748
           ++ D +D +     D    EEE  +       ++Q  ++  KV+    +L+  K
Sbjct: 167 QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDK 220


>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
          Length = 564

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 68/282 (24%), Positives = 116/282 (41%), Gaps = 31/282 (10%)

Query: 490 DPEQDREISDHVLRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHD 549
           D E++ E  +   R       GE+ G  +   +  + L  D P F +E+ +D +I  K D
Sbjct: 187 DKEKEEEEEEKPKRGSIGENQGEEKGTKVQ--AKREKLQEDKPTFKKEEIKDEKI--KKD 242

Query: 550 NLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTAR 609
                 K+ KE++ S    KK     K            +    +SR   + S+ +  A 
Sbjct: 243 ------KEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAE 296

Query: 610 TSPVT--ARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFK----KVLEKEKK 663
            +P     + LE L R           K    Q  E A+EL +    +    KVLE+E++
Sbjct: 297 GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ-EAALELEELKKKREERRKVLEEEEQ 355

Query: 664 RKKRSEDESETEDEEEKSQEDQEQKRKRRKT---RQPDAKDGDSYDPYDFS--------- 711
           R+K+ E + +  +EEEK +  +E +R+R +    RQ   +DG S D   F          
Sbjct: 356 RRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSL 415

Query: 712 --DTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVAL 751
             +   E       K++  + T ++  V   +SRL+ +  A+
Sbjct: 416 KIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAI 457



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 36/174 (20%), Positives = 72/174 (41%), Gaps = 12/174 (6%)

Query: 584 QESATYIAEEYSRLRSQDSMSSDTARTSPVTARTL---ETLIRLATAHAKARMSKTVDLQ 640
           +ES   + ++   + +Q+S+  + A+T+    +     E       A  + R  K   LQ
Sbjct: 56  EESLGQVTDQVE-VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR--LQ 112

Query: 641 DAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQ------KRKRRKT 694
           +A E  +          L    +R +    E+ET ++EEKS+  QE+      +   +  
Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSY 172

Query: 695 RQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFK 748
           ++ D +D +     D    EEE  +       ++Q  ++  KV+    +L+  K
Sbjct: 173 QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDK 226


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 61/245 (24%), Positives = 102/245 (41%), Gaps = 29/245 (11%)

Query: 527 LATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQES 586
           L  D P F +E+ +D +I  K D      K+ KE++ S    KK     K          
Sbjct: 451 LQEDKPTFKKEEIKDEKI--KKD------KEPKEEVKSFMDRKKGFTEVKSQNGEFMTHK 502

Query: 587 ATYIAEEYSRLRSQDSMSSDTARTSPVT--ARTLETLIRLATAHAKARMSKTVDLQDAEE 644
             +    +SR   + S+ +  A  +P     + LE L R           K    Q  E 
Sbjct: 503 LKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ-EA 561

Query: 645 AVELVQYAYFK----KVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKT---RQP 697
           A+EL +    +    KVLE+E++R+K+ E + +  +EEEK +  +E +R+R +    RQ 
Sbjct: 562 ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621

Query: 698 DAKDGDSYDPYDFS-----------DTEEEMPQVHTPKTADSQETKESQKVELSESRLKA 746
             +DG S D   F            +   E       K++  + T ++  V   +SRL+ 
Sbjct: 622 MPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQ 681

Query: 747 FKVAL 751
           +  A+
Sbjct: 682 YTSAI 686



 Score = 37.0 bits (84), Expect = 0.073
 Identities = 53/271 (19%), Positives = 108/271 (39%), Gaps = 43/271 (15%)

Query: 535 SQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEY 594
           S+E +Q+ +  +  D + H  K ++E    A   +  +   +  +  +  E    IA+E 
Sbjct: 235 SEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEE--RERIKAEQDKKIADER 292

Query: 595 SRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYF 654
           +R+ +++  ++          R  E   R+     +A          AEE          
Sbjct: 293 ARIEAEEKAAAQERER-----REAEERERMREEEKRA----------AEER--------- 328

Query: 655 KKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTE 714
               ++ K+ +KR+ +E +   EEEK   ++ Q+ K  + R  + +     +       E
Sbjct: 329 ----QRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAE-------E 377

Query: 715 EEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALLDVFREAHAQSIGMNRL-TESIN 773
           EE  +V   K     +  E +K  + E+++K  KV      +  + +    ++L T  + 
Sbjct: 378 EEKAKVEEQK---RNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLK 434

Query: 774 RDSEEPFSSVEIQAALSKMQDDNQVMVSEGI 804
           +  EE     ++QA   K+Q+D      E I
Sbjct: 435 KQGEE--KGTKVQAKREKLQEDKPTFKKEEI 463



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 19/199 (9%)

Query: 584 QESATYIAEEYSRLRSQDSMSSDTARTSPVTARTL---ETLIRLATAHAKARMSKTVDLQ 640
           +ES   + ++   + +Q+S+  + A+T+    +     E       A  + R  K   LQ
Sbjct: 56  EESLGQVTDQVE-VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR--LQ 112

Query: 641 DAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAK 700
           +A E  +          L    +R +    E+ET ++EEKS+  QE     R   +    
Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE-----RYEIEETET 167

Query: 701 DGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALLDVFREAHA 760
              SY   D+ D EE   +    K  + +E ++ ++  + E+++   +V + +   E+  
Sbjct: 168 VTKSYQKNDWRDAEENKKE---DKEKEEEEEEKPKRGSIGENQV---EVMVEEKTTESQE 221

Query: 761 QSIGMNRLTESINRDSEEP 779
           +++ M+     I+  SEEP
Sbjct: 222 ETVVMSLKNGQIS--SEEP 238


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 28/122 (22%), Positives = 64/122 (52%), Gaps = 7/122 (5%)

Query: 630 KARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESET---EDEEEKSQEDQE 686
           K +  +T + ++ EE  E  +    K+   KEK+++KR E E +    E E+ K +E++E
Sbjct: 4   KKKKKETEETEETEETEEEEE----KEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59

Query: 687 QKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKA 746
           +KRKR++ ++ + ++ +  +  +  + EEE  +    +    +  ++ ++ E  + R + 
Sbjct: 60  KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119

Query: 747 FK 748
            K
Sbjct: 120 TK 121



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 32/120 (26%), Positives = 63/120 (52%), Gaps = 5/120 (4%)

Query: 630 KARMSKTVDLQDAEEAVELVQYAYFK-KVLEKEKKRKKRSEDESETEDEEEKSQEDQEQK 688
           K    +T + ++ EE  E       K K   KEK++KK+++   ETE  +EK +E++++K
Sbjct: 7   KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTK---ETEKRKEKEEEEKKRK 63

Query: 689 RKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFK 748
           RKR+K ++ + ++ +  +  +  + EEE  +    K    +  KE ++ +  + R K  K
Sbjct: 64  RKRKKKKEEEEREEEEEEEEEEKE-EEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 24/86 (27%), Positives = 48/86 (55%), Gaps = 1/86 (1%)

Query: 659 EKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSD-TEEEM 717
           +K+KK+KK +E+  ETE+ EE+ +++ ++K KR++ R+   K   + +     +  EEE 
Sbjct: 1   KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60

Query: 718 PQVHTPKTADSQETKESQKVELSESR 743
            +    K    +E +E ++ E  E +
Sbjct: 61  KRKRKRKKKKEEEEREEEEEEEEEEK 86


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 28/121 (23%), Positives = 63/121 (52%), Gaps = 7/121 (5%)

Query: 628  HAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQ---ED 684
            H    M   +D  + +E++   +    ++  E+E++  +  E+E + E+E E+ Q   E+
Sbjct: 2225 HFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE 2284

Query: 685  QEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRL 744
            +E+K+K+++ ++ + ++ +      F + EE M +  T   +D +E +ES  +E    R 
Sbjct: 2285 EEKKKKKKEKKKEEVQEKEEV----FEEKEEIMSEEETESLSDEEEEEESCSLEEEVDRE 2340

Query: 745  K 745
            K
Sbjct: 2341 K 2341



 Score = 36.6 bits (83), Expect = 0.096
 Identities = 35/149 (23%), Positives = 66/149 (44%), Gaps = 31/149 (20%)

Query: 630  KARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKR 689
            K + S  VD  ++EE        +F +  E E    +  + ES + +EEE+ +E++E++ 
Sbjct: 2210 KEKFSSQVDEVESEE--------HFSE--EMESLLDELEKQESLSSEEEEEREEEEEREE 2259

Query: 690  KRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKV 749
            +  +  + + K+          + E E  QV   +    ++ KE +K E+ E        
Sbjct: 2260 EEVREEEEERKE----------EEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE------ 2303

Query: 750  ALLDVFREAHAQSIGMNRLTESINRDSEE 778
               +VF E   + I     TES++ + EE
Sbjct: 2304 ---EVFEE--KEEIMSEEETESLSDEEEE 2327



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 11/88 (12%)

Query: 659  EKEKKRKKRSEDESETEDEEEK-SQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEM 717
            ++ +  KKR+++E +   EEEK +QE+++  ++ RK  Q   K          +  + EM
Sbjct: 1580 KRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVK---------ITQDDREM 1630

Query: 718  PQVHTPKTADSQETKESQKVELSESRLK 745
             Q    K A  +ET   +  +LS+   K
Sbjct: 1631 AQAE-GKFAQKEETLAQRGEKLSQEAEK 1657


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 20/80 (25%), Positives = 47/80 (58%)

Query: 652 AYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFS 711
           A+ +++ EKE++  K+ E+  + E++EE+ +E+ +QK +  + R  + ++G+S D  D  
Sbjct: 368 AFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDED 427

Query: 712 DTEEEMPQVHTPKTADSQET 731
           +   + P+    +   ++ET
Sbjct: 428 EDGGQKPEGEPQQDPGTEET 447



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 19/74 (25%), Positives = 38/74 (51%)

Query: 668 SEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTAD 727
           S +E E+EDEE  S+++ ++ R+ R   +   K   ++        EEEM +    K  +
Sbjct: 332 SPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKE 391

Query: 728 SQETKESQKVELSE 741
            +E +E ++++  E
Sbjct: 392 EKEEEEEEEMKQKE 405



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 4/96 (4%)

Query: 655 KKVLEKEKKRKKRSEDESET----EDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDF 710
           KK  E +KK +K  E+E E     E+EE +++ ++E + K  +    D       +P   
Sbjct: 382 KKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQD 441

Query: 711 SDTEEEMPQVHTPKTADSQETKESQKVELSESRLKA 746
             TEE   +V      ++Q+    + +E+  + + A
Sbjct: 442 PGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHA 477


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 38/176 (21%), Positives = 84/176 (47%), Gaps = 11/176 (6%)

Query: 582 LTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETLIRLATAHAKARMSKTVDLQD 641
           L+  S+T   E       Q S +S    ++P+  R  +  ++ +T   K R+ +     D
Sbjct: 287 LSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLR-RITKKFVKGSTEKNKLRLQR-----D 340

Query: 642 AEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKD 701
            E   + ++    ++  EK K+  KR+++E++ + EEEK  +++E++ KR K  +  A+ 
Sbjct: 341 QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEK 400

Query: 702 GDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVALLDVFRE 757
               +     +  +E  +    K  + ++ +E +++   E R+KA K  +   F++
Sbjct: 401 QRLKE-----ERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQK 451


>gi|148612801 KIAA1009 protein [Homo sapiens]
          Length = 1403

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 55/251 (21%), Positives = 113/251 (45%), Gaps = 46/251 (18%)

Query: 531  DPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYI 590
            D + S+  Q++ ++  + + L+  ++K + KM S A M ++ +  + +K    +++A +I
Sbjct: 1166 DSHVSEVLQENYRLKNELEGLI--SEKNELKMKSEAVMNQFENSMRRVK----EDTAAHI 1219

Query: 591  AE-------EYSRLRSQDSMSSDTARTSPVTAR--TLETLIRLATAHAKARMSKTVDLQD 641
            A        E  +L  Q+++ + +++ + +  +  T E LIR   +      SK   L  
Sbjct: 1220 ASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVV 1279

Query: 642  AEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKD 701
            +E   E++Q     K+LE+ ++ K+    E +     EK  +  E +  +R         
Sbjct: 1280 SEVREEILQKE-ITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQR--------- 1329

Query: 702  GDSYDPYDFSDTEEEMPQV--HTPKTADSQETKESQK----VELSESRLKAFKVAL---L 752
                        E+E+ Q+   T +  ++++ KE +K     +L    L+ F+  L   L
Sbjct: 1330 ------------EQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSIL 1377

Query: 753  DVFREAHAQSI 763
            DV RE H Q +
Sbjct: 1378 DVLRELHRQGV 1388



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 40/192 (20%), Positives = 82/192 (42%), Gaps = 26/192 (13%)

Query: 627  AHAKARM--------SKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDE- 677
            AHAKA++        +K  ++QD  + VE +Q          + +R   S   S+  +E 
Sbjct: 1081 AHAKAKLVRLNEELAAKKREIQDLSKTVERLQ----------KDRRMMLSNQNSKGREEM 1130

Query: 678  -EEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQK 736
              +++++D     K      P   D   Y P+ F+D+          +  +  E   S+K
Sbjct: 1131 SAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEK 1190

Query: 737  VEL---SESRLKAFKVALLDVFREAHAQSIGMNRLTESINRDSEEPFSSVEIQAALSKMQ 793
             EL   SE+ +  F+ ++  V  +  A    +  L  S  R+ E+      ++ + SK+ 
Sbjct: 1191 NELKMKSEAVMNQFENSMRRVKEDTAAH---IASLKASHQREIEKLLCQNAVENSSSKVA 1247

Query: 794  DDNQVMVSEGII 805
            + N+ + ++ ++
Sbjct: 1248 ELNRKIATQEVL 1259


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 68/275 (24%), Positives = 115/275 (41%), Gaps = 38/275 (13%)

Query: 525  DILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQ 584
            D+ A D+ N  +  Q   Q++E    L     ++K++ ++AA  KK     K ++  L  
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETEL---EDERKQRALAAAAKKKLEGDLKDLE--LQA 1633

Query: 585  ESATYIAEE-YSRLRSQDSMSSD-----------------TARTSPVTARTLET-LIRLA 625
            +SA    EE   +LR   +   D                 TA+ +   A++LE  L++L 
Sbjct: 1634 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1693

Query: 626  TAHAKA-RMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQED 684
               A A R  K  DL+  E A EL      +  L+ EK+R +    + E E EEE+   +
Sbjct: 1694 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1753

Query: 685  QEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRL 744
                R R+ T+Q +    +         TE    Q    K   +++  E Q  EL  S+L
Sbjct: 1754 AMSDRVRKATQQAEQLSNE-------LATERSTAQ----KNESARQQLERQNKEL-RSKL 1801

Query: 745  KAFKVALLDVFREA-HAQSIGMNRLTESINRDSEE 778
               + A+   F+    A    + +L E + +++ E
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 68/275 (24%), Positives = 115/275 (41%), Gaps = 38/275 (13%)

Query: 525  DILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQ 584
            D+ A D+ N  +  Q   Q++E    L     ++K++ ++AA  KK     K ++  L  
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETEL---EDERKQRALAAAAKKKLEGDLKDLE--LQA 1640

Query: 585  ESATYIAEE-YSRLRSQDSMSSD-----------------TARTSPVTARTLET-LIRLA 625
            +SA    EE   +LR   +   D                 TA+ +   A++LE  L++L 
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700

Query: 626  TAHAKA-RMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQED 684
               A A R  K  DL+  E A EL      +  L+ EK+R +    + E E EEE+   +
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1760

Query: 685  QEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRL 744
                R R+ T+Q +    +         TE    Q    K   +++  E Q  EL  S+L
Sbjct: 1761 AMSDRVRKATQQAEQLSNE-------LATERSTAQ----KNESARQQLERQNKEL-RSKL 1808

Query: 745  KAFKVALLDVFREA-HAQSIGMNRLTESINRDSEE 778
               + A+   F+    A    + +L E + +++ E
Sbjct: 1809 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1843


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 68/275 (24%), Positives = 115/275 (41%), Gaps = 38/275 (13%)

Query: 525  DILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQ 584
            D+ A D+ N  +  Q   Q++E    L     ++K++ ++AA  KK     K ++  L  
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETEL---EDERKQRALAAAAKKKLEGDLKDLE--LQA 1640

Query: 585  ESATYIAEE-YSRLRSQDSMSSD-----------------TARTSPVTARTLET-LIRLA 625
            +SA    EE   +LR   +   D                 TA+ +   A++LE  L++L 
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1700

Query: 626  TAHAKA-RMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQED 684
               A A R  K  DL+  E A EL      +  L+ EK+R +    + E E EEE+   +
Sbjct: 1701 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1760

Query: 685  QEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRL 744
                R R+ T+Q +    +         TE    Q    K   +++  E Q  EL  S+L
Sbjct: 1761 AMSDRVRKATQQAEQLSNE-------LATERSTAQ----KNESARQQLERQNKEL-RSKL 1808

Query: 745  KAFKVALLDVFREA-HAQSIGMNRLTESINRDSEE 778
               + A+   F+    A    + +L E + +++ E
Sbjct: 1809 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1843


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 68/275 (24%), Positives = 115/275 (41%), Gaps = 38/275 (13%)

Query: 525  DILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQ 584
            D+ A D+ N  +  Q   Q++E    L     ++K++ ++AA  KK     K ++  L  
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETEL---EDERKQRALAAAAKKKLEGDLKDLE--LQA 1633

Query: 585  ESATYIAEE-YSRLRSQDSMSSD-----------------TARTSPVTARTLET-LIRLA 625
            +SA    EE   +LR   +   D                 TA+ +   A++LE  L++L 
Sbjct: 1634 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1693

Query: 626  TAHAKA-RMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQED 684
               A A R  K  DL+  E A EL      +  L+ EK+R +    + E E EEE+   +
Sbjct: 1694 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1753

Query: 685  QEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRL 744
                R R+ T+Q +    +         TE    Q    K   +++  E Q  EL  S+L
Sbjct: 1754 AMSDRVRKATQQAEQLSNE-------LATERSTAQ----KNESARQQLERQNKEL-RSKL 1801

Query: 745  KAFKVALLDVFREA-HAQSIGMNRLTESINRDSEE 778
               + A+   F+    A    + +L E + +++ E
Sbjct: 1802 HEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 46/226 (20%), Positives = 97/226 (42%), Gaps = 21/226 (9%)

Query: 579  KPVLTQESATYIAEEYSRLRSQDSM--SSDTARTSPVTARTLETLIRLATAHAKARMSKT 636
            +P L  ES T   E+ SR     S+  SS T  TSP +  +L+     + +H K    + 
Sbjct: 1696 EPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQ 1755

Query: 637  ------------VDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQED 684
                          ++D+ E  EL +     K  EK+++ +++    S  + +++K +  
Sbjct: 1756 RKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELR 1815

Query: 685  QEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKES--QKVELSES 742
             +++R+R KT   +    +   P +      EM ++H    ++   + ES  +  E+S  
Sbjct: 1816 AQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPE 1875

Query: 743  RL----KAFKV-ALLDVFREAHAQSIGMNRLTESINRDSEEPFSSV 783
            ++    K +K+   + ++     QSI     ++   + +EE +  +
Sbjct: 1876 KIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEM 1921


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 46/226 (20%), Positives = 97/226 (42%), Gaps = 21/226 (9%)

Query: 579  KPVLTQESATYIAEEYSRLRSQDSM--SSDTARTSPVTARTLETLIRLATAHAKARMSKT 636
            +P L  ES T   E+ SR     S+  SS T  TSP +  +L+     + +H K    + 
Sbjct: 1696 EPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQ 1755

Query: 637  ------------VDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQED 684
                          ++D+ E  EL +     K  EK+++ +++    S  + +++K +  
Sbjct: 1756 RKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELR 1815

Query: 685  QEQKRKRRKTRQPDAKDGDSYDPYDFSDTEEEMPQVHTPKTADSQETKES--QKVELSES 742
             +++R+R KT   +    +   P +      EM ++H    ++   + ES  +  E+S  
Sbjct: 1816 AQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPE 1875

Query: 743  RL----KAFKV-ALLDVFREAHAQSIGMNRLTESINRDSEEPFSSV 783
            ++    K +K+   + ++     QSI     ++   + +EE +  +
Sbjct: 1876 KIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEM 1921


>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
          Length = 597

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 20/49 (40%), Positives = 32/49 (65%), Gaps = 1/49 (2%)

Query: 659 EKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDP 707
           EK+KK+KK+SE E   +DEE + +++ E+KRKR +       + D +DP
Sbjct: 65  EKKKKKKKKSEKEKHLDDEERRKRKE-EKKRKREREHCDTEGEADDFDP 112



 Score = 33.9 bits (76), Expect = 0.62
 Identities = 22/94 (23%), Positives = 45/94 (47%), Gaps = 4/94 (4%)

Query: 652 AYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQE-QKRKRRKTRQPDAKDGDS---YDP 707
           +Y+    + E++R K  + + + + E+EK  +D+E +KRK  K R+ + +  D+    D 
Sbjct: 50  SYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADD 109

Query: 708 YDFSDTEEEMPQVHTPKTADSQETKESQKVELSE 741
           +D     E  P    P  A   +  E++   + +
Sbjct: 110 FDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQ 143


>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
          Length = 532

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 53/223 (23%), Positives = 91/223 (40%), Gaps = 21/223 (9%)

Query: 549 DNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTA 608
           D  +   K+ KE++ S    KK     K            +    +SR   + S+ +  A
Sbjct: 204 DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEA 263

Query: 609 RTSPVT--ARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFK----KVLEKEK 662
             +P     + LE L R           K    Q  E A+EL +    +    KVLE+E+
Sbjct: 264 EGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ-EAALELEELKKKREERRKVLEEEE 322

Query: 663 KRKKRSEDESETEDEEEKSQEDQEQKRKRRKT---RQPDAKDGDSYDPYDFS-------- 711
           +R+K+ E + +  +EEEK +  +E +R+R +    RQ   +DG S D   F         
Sbjct: 323 QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSS 382

Query: 712 ---DTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVAL 751
              +   E       K++  + T ++  V   +SRL+ +  A+
Sbjct: 383 LKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAI 425



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 37/169 (21%), Positives = 72/169 (42%), Gaps = 14/169 (8%)

Query: 584 QESATYIAEEYSRLRSQDSMSSDTARTSPVTARTL---ETLIRLATAHAKARMSKTVDLQ 640
           +ES   + ++   + +Q+S+  + A+T+    +     E       A  + R  K   LQ
Sbjct: 50  EESLGQVTDQVE-VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR--LQ 106

Query: 641 DAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAK 700
           +A E  +          L    +R +    E+ET ++EEKS+  QE     R   +    
Sbjct: 107 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE-----RYEIEETET 161

Query: 701 DGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKV 749
              SY   D+ D EE   +    K  + +E ++ ++  + E+++K  K+
Sbjct: 162 VTKSYQKNDWRDAEENKKE---DKEKEEEEEEKPKRGSIGENQIKDEKI 207


>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
          Length = 538

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 53/223 (23%), Positives = 91/223 (40%), Gaps = 21/223 (9%)

Query: 549 DNLLHGTKKKKEKMVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTA 608
           D  +   K+ KE++ S    KK     K            +    +SR   + S+ +  A
Sbjct: 210 DEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEA 269

Query: 609 RTSPVT--ARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFK----KVLEKEK 662
             +P     + LE L R           K    Q  E A+EL +    +    KVLE+E+
Sbjct: 270 EGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ-EAALELEELKKKREERRKVLEEEE 328

Query: 663 KRKKRSEDESETEDEEEKSQEDQEQKRKRRKT---RQPDAKDGDSYDPYDFS-------- 711
           +R+K+ E + +  +EEEK +  +E +R+R +    RQ   +DG S D   F         
Sbjct: 329 QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSS 388

Query: 712 ---DTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKVAL 751
              +   E       K++  + T ++  V   +SRL+ +  A+
Sbjct: 389 LKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAI 431



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 37/169 (21%), Positives = 72/169 (42%), Gaps = 14/169 (8%)

Query: 584 QESATYIAEEYSRLRSQDSMSSDTARTSPVTARTL---ETLIRLATAHAKARMSKTVDLQ 640
           +ES   + ++   + +Q+S+  + A+T+    +     E       A  + R  K   LQ
Sbjct: 56  EESLGQVTDQVE-VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKR--LQ 112

Query: 641 DAEEAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAK 700
           +A E  +          L    +R +    E+ET ++EEKS+  QE     R   +    
Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE-----RYEIEETET 167

Query: 701 DGDSYDPYDFSDTEEEMPQVHTPKTADSQETKESQKVELSESRLKAFKV 749
              SY   D+ D EE   +    K  + +E ++ ++  + E+++K  K+
Sbjct: 168 VTKSYQKNDWRDAEENKKE---DKEKEEEEEEKPKRGSIGENQIKDEKI 213


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 10/95 (10%)

Query: 651 YAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGDSYDPYDF 710
           + + K   E E +R+  SEDE E ++EEE  +E++E+          +A  GD YD ++ 
Sbjct: 363 FTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEE----------EAGYGDGYDDWET 412

Query: 711 SDTEEEMPQVHTPKTADSQETKESQKVELSESRLK 745
            + EE +      +  + +E  ES  V ++   +K
Sbjct: 413 DEDEESLGDEEEEEEEEEEEVLESCMVGVARDSVK 447


>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
          Length = 1646

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 34/138 (24%), Positives = 68/138 (49%), Gaps = 16/138 (11%)

Query: 598 RSQDSMSSDTARTSPVTA------RTLETLI--------RLATAHAKARMSKTVDLQDAE 643
           RS++S+SS T+    V        + +E+ I        + +  HAK   SK   +Q  E
Sbjct: 818 RSEESISSGTSTARSVEEVEEENDQEMESFITEEVLGQQKKSPLHAKMDESKEGSIQGLE 877

Query: 644 EAVELVQYAYFKKVLEKEKKRKKRSEDESETEDEEEKSQEDQEQKRKRRKTRQPDAKDGD 703
           E +++ +       L +E   K + E + E+E+E+EK +E++E+K +  K  +   ++ +
Sbjct: 878 E-MQVEREGSLNPSLNEENV-KGQGEKKEESEEEDEKEEEEEEEKLEEEKEEKEAQEEQE 935

Query: 704 SYDPYDFSDTEEEMPQVH 721
           S    +  D EE + +++
Sbjct: 936 SLSVGEEEDKEEGLEEIY 953


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,730,805
Number of Sequences: 37866
Number of extensions: 1326272
Number of successful extensions: 22624
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 424
Number of HSP's successfully gapped in prelim test: 470
Number of HSP's that attempted gapping in prelim test: 11474
Number of HSP's gapped (non-prelim): 6069
length of query: 808
length of database: 18,247,518
effective HSP length: 110
effective length of query: 698
effective length of database: 14,082,258
effective search space: 9829416084
effective search space used: 9829416084
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.