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Search of human proteins with 65301139
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|65301139 ATPase, class II, type 9A [Homo sapiens]
(1047 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 2083 0.0
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 1604 0.0
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 467 e-131
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 461 e-129
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 455 e-128
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 454 e-127
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 454 e-127
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 445 e-124
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 445 e-124
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 439 e-123
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 437 e-122
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 421 e-117
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 411 e-114
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 335 2e-91
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 265 1e-70
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 251 3e-66
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 235 2e-61
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 143 7e-34
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 90 1e-17
gi|148839292 ATPase type 13A3 [Homo sapiens] 86 1e-16
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 85 4e-16
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 82 3e-15
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 73 2e-12
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 73 2e-12
gi|66932949 ATPase type 13A4 [Homo sapiens] 70 1e-11
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] 69 2e-11
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] 69 2e-11
gi|170016077 ATPase type 13A1 [Homo sapiens] 66 2e-10
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 65 4e-10
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 65 4e-10
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 2083 bits (5397), Expect = 0.0
Identities = 1047/1047 (100%), Positives = 1047/1047 (100%)
Query: 1 MTDNIPLQPVRQKKRMDSRPRAGCCEWLRCCGGGEARPRTVWLGHPEKRDQRYPRNVINN 60
MTDNIPLQPVRQKKRMDSRPRAGCCEWLRCCGGGEARPRTVWLGHPEKRDQRYPRNVINN
Sbjct: 1 MTDNIPLQPVRQKKRMDSRPRAGCCEWLRCCGGGEARPRTVWLGHPEKRDQRYPRNVINN 60
Query: 61 QKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIRE 120
QKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIRE
Sbjct: 61 QKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIRE 120
Query: 121 AVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSE 180
AVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSE
Sbjct: 121 AVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSE 180
Query: 181 KNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT 240
KNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT
Sbjct: 181 KNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT 240
Query: 241 REDSDPPISESLSIENTLWAGTVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEV 300
REDSDPPISESLSIENTLWAGTVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEV
Sbjct: 241 REDSDPPISESLSIENTLWAGTVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEV 300
Query: 301 NCLTKILFGALVVVSLVMVALQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSW 360
NCLTKILFGALVVVSLVMVALQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSW
Sbjct: 301 NCLTKILFGALVVVSLVMVALQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSW 360
Query: 361 VIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDE 420
VIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDE
Sbjct: 361 VIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDE 420
Query: 421 VQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTD 480
VQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTD
Sbjct: 421 VQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTD 480
Query: 481 QAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQ 540
QAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQ
Sbjct: 481 QAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQ 540
Query: 541 IFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLV 600
IFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLV
Sbjct: 541 IFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLV 600
Query: 601 VAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVR 660
VAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVR
Sbjct: 601 VAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVR 660
Query: 661 PTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFR 720
PTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFR
Sbjct: 661 PTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFR 720
Query: 721 RKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLT 780
RKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLT
Sbjct: 721 RKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLT 780
Query: 781 CAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSA 840
CAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSA
Sbjct: 781 CAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSA 840
Query: 841 ALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKS 900
ALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKS
Sbjct: 841 ALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKS 900
Query: 901 EVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIVAISFTS 960
EVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIVAISFTS
Sbjct: 901 EVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIVAISFTS 960
Query: 961 LILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFIDVYFIATLSFLWKVSVIT 1020
LILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFIDVYFIATLSFLWKVSVIT
Sbjct: 961 LILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEFIDVYFIATLSFLWKVSVIT 1020
Query: 1021 LVSCLPLYVLKYLRRRFSPPSYSKLTS 1047
LVSCLPLYVLKYLRRRFSPPSYSKLTS
Sbjct: 1021 LVSCLPLYVLKYLRRRFSPPSYSKLTS 1047
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 1604 bits (4154), Expect = 0.0
Identities = 791/1049 (75%), Positives = 909/1049 (86%), Gaps = 25/1049 (2%)
Query: 24 CCEWLR--CCGGGEARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFF 81
CC WL C E + RTVWLG PEK ++++PRN I NQKYN FTF+PGVL+ QFK+F
Sbjct: 99 CCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFL 158
Query: 82 NLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSR 141
NLYFL+++CSQFVP +++G LYTYW PLGFVLAVT+ REA++E R + RDKEVNSQ+YS+
Sbjct: 159 NLYFLVISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSK 218
Query: 142 LTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLR 201
LT RG V+VKSS+IQVGDLIIVEKNQR+P+DM+FLRTSEK GSCF+RTDQLDGETDWKL+
Sbjct: 219 LTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLK 278
Query: 202 LPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAG 261
+ V+CTQ+LP DL I +YVYA++P +DIH+F GTFTREDSDPPI ESLSIENTLWA
Sbjct: 279 VAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWAS 338
Query: 262 TVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVAL 321
T+VASGTV+GVV+YTG+E RSVMNTSNP++K+GL DLE+N LTK LF ALV +S+VMV L
Sbjct: 339 TIVASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTL 398
Query: 322 QHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQ 381
Q F G WY + RFLLLFS IIPISLRVNLDMGK VY W++ +D IPGTVVR+STIPE+
Sbjct: 399 QGFVGPWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEE 458
Query: 382 LGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQ-QSQ------ 434
LGR+ YLLTDKTGTLTQNEMIFKRLHLGTV+YG D+MDE+QSH+ Y+Q QSQ
Sbjct: 459 LGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNT 518
Query: 435 -DPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESN-GVTDQ---AEAEKQYE 489
P +K + KVR+++SSR+HEAVKAI LCHNVTPVYES GVT++ AEA++ +
Sbjct: 519 GSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFS 578
Query: 490 DSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESK 549
D R YQASSPDEVALVQWTESVGLTLV RD +SMQL+TP Q+L+F ILQ+FPFT ESK
Sbjct: 579 DENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESK 638
Query: 550 RMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLAEE 609
RMG+IVRDEST EITFYMKGADV M+ IVQYNDWLEEECGNMAREGLR LVVAKK+L EE
Sbjct: 639 RMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEE 698
Query: 610 QYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNA 669
QYQDFE+RY QAKLS+HDRSLKVA V+ESLE EMELLCLTGVEDQLQADVRPTLE LRNA
Sbjct: 699 QYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNA 758
Query: 670 GIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVI 729
GIK+WMLTGDKLETATC AK++HLV+R QDIH+FR VT+RGEAHLELNAFRRKHDCALVI
Sbjct: 759 GIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVI 818
Query: 730 SGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGND 789
SGDSLEVCLKYYE+EF+ELACQCPAVVCCRC+PTQKA+IV LLQ+ TG+ TCA+GDGGND
Sbjct: 819 SGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGND 878
Query: 790 VSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHR 849
VSMIQ +DCG+G+EGKEGKQASLAADFSITQF+H+GRLLMVHGRNSYKRSAAL QFV+HR
Sbjct: 879 VSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHR 938
Query: 850 SLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPEL 909
L ISTMQAVFSSVFYFASVPLYQGFL++GY+TIYTMFPVFSLVLD+DVK E+AMLYPEL
Sbjct: 939 GLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPEL 998
Query: 910 YKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIVAISFTSLILTELLMV 969
YKDL KGR LS+KTFLIWVLISIYQG +MYGAL+LFESEFVH+VAISFT+LILTELLMV
Sbjct: 999 YKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVHVVAISFTALILTELLMV 1058
Query: 970 ALTIQTWHWLMTVAELLSLACYIASLVFLHE-----------FIDVYFIATLSFLWKVSV 1018
ALT++TWHWLM VAE LSL CY++SL FL+E F+DV FI T++FLWKVS
Sbjct: 1059 ALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSA 1118
Query: 1019 ITLVSCLPLYVLKYLRRRFSPPSYSKLTS 1047
IT+VSCLPLYVLKYLRR+ SPPSY KL S
Sbjct: 1119 ITVVSCLPLYVLKYLRRKLSPPSYCKLAS 1147
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 467 bits (1201), Expect = e-131
Identities = 305/1014 (30%), Positives = 510/1014 (50%), Gaps = 106/1014 (10%)
Query: 39 RTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMR 98
RT+++ P+ ++ N ++ KYN TFLP L++QF+ N +FL +A Q +P++
Sbjct: 37 RTIFINQPQLT--KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVS 94
Query: 99 LGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVG 158
YT VPL F+LAV I+E +E+I+ + D VN + L V + VG
Sbjct: 95 PTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVG 154
Query: 159 DLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQ 218
D++I++ + +PAD + L +SE C++ T LDGET+ K+R + T + L++
Sbjct: 155 DIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMR 214
Query: 219 IRSYVYAEEPNIDIHNFVGTFTRED-------SDPPISESLSIENTLWAGTVVASGTVVG 271
I + E PN +++FVG + +D + + NT W V G
Sbjct: 215 ISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQW---------VHG 265
Query: 272 VVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA------LQHFA 325
+V+YTG + + + N+++P K+ + N ILF L+ +SLV +H
Sbjct: 266 IVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSG 325
Query: 326 GRWYLQI------------IRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI----- 368
WYL + + F++LF+N+IPISL V L++ K ++ I D +
Sbjct: 326 KDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPT 385
Query: 369 -PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSM--DEVQSHI 425
+ R+S + E+LG++ Y+ +DKTGTLT N M FK+ + VAYG +S DE
Sbjct: 386 DTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFGDEKTFSD 445
Query: 426 FSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAE 485
S+ + P + + E + +A+CH P E + +
Sbjct: 446 SSLLENLQNNHPT--------------APIICEFLTMMAVCHTAVPEREGDKI------- 484
Query: 486 KQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFT 545
+YQA+SPDE ALV+ + + GR S+ + + G + + +L + FT
Sbjct: 485 --------IYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEE-RYELLNVLEFT 535
Query: 546 YESKRMGIIVRDESTGEITFYMKGADVV----MAGIVQYNDWLEEECGNMAREGLRVLVV 601
KRM +IVR S G++ Y KGAD V +A +Y + + A EGLR L
Sbjct: 536 SARKRMSVIVRTPS-GKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCF 594
Query: 602 AKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRP 661
A ++E +Q++ A Y +A SV +R LK+ E +E ++LL T +ED+LQ V
Sbjct: 595 AVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPE 654
Query: 662 TLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEA--------- 712
T+ETL A IK+W+LTGDK ETA + L+ +N + +V N G
Sbjct: 655 TIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGM----IVINEGSLDGTRETLSR 710
Query: 713 HLEL--NAFRRKHDCALVISGDSLEVCLKY-YEYEFMELACQCPAVVCCRCAPTQKAQIV 769
H +A R+++D AL+I G +L+ L + F++LA C AV+CCR +P QK+++V
Sbjct: 711 HCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKSEVV 770
Query: 770 RLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLM 829
+++++ +T A+GDG NDVSMIQ + GVG+ G EG QA+ ++D+SI QFK+L LLM
Sbjct: 771 EMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLM 830
Query: 830 VHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPV 889
+HG +Y R + + ++++ + ++ F+ V F+ L++ + I Y+ ++T P
Sbjct: 831 IHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTAMPP 890
Query: 890 FSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFE- 947
+L + ++ + E + YPELYK + K F + L ++ + + L +
Sbjct: 891 LTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKALQY 950
Query: 948 ---------SEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYI 992
S+++ + +T +++T L L W W +A S+A ++
Sbjct: 951 GTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV 1004
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 461 bits (1186), Expect = e-129
Identities = 304/1017 (29%), Positives = 515/1017 (50%), Gaps = 97/1017 (9%)
Query: 39 RTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMR 98
RT+++ P+ ++ N ++ KYN TFLP L++QF+ N +FL +A Q +P++
Sbjct: 37 RTIFINQPQLT--KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVS 94
Query: 99 LGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVG 158
YT VPL F+LAV I+E +E+I+ + D VN + L V + VG
Sbjct: 95 PTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVG 154
Query: 159 DLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQ 218
+++ V + +PAD+I L +SE C++ T LDGET+ K+R + T + L++
Sbjct: 155 EIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMR 214
Query: 219 IRSYVYAEEPNIDIHNFVGTFTRED-------SDPPISESLSIENTLWAGTVVASGTVVG 271
I + E PN +++FVG + +D + + NT W V G
Sbjct: 215 ISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQW---------VHG 265
Query: 272 VVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA------LQHFA 325
+V+YTG + + + N+++P K+ + N ILF L+ +SLV +H
Sbjct: 266 IVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSG 325
Query: 326 GRWYLQI------------IRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI----- 368
WYL + + F++LF+N+IPISL V L++ K ++ I D +
Sbjct: 326 KDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPT 385
Query: 369 -PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFS 427
+ R+S + E+LG++ Y+ +DKTGTLT N M FK+ + VAYG + E + + S
Sbjct: 386 DTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYG--HVPEPEDYGCS 443
Query: 428 IYTQQSQDPPAQKGPTLTTKVRRTMSSR-----VHEAVKAIALCHNVTPVYESNGVTDQA 482
Q+ +K + ++ + ++ + E + +A+CH P E + +
Sbjct: 444 PDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKI---- 499
Query: 483 EAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIF 542
+YQA+SPDE ALV+ + + GR S+ + + G + + +L +
Sbjct: 500 -----------IYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQEE-RYELLNVL 547
Query: 543 PFTYESKRMGIIVRDESTGEITFYMKGADVV----MAGIVQYNDWLEEECGNMAREGLRV 598
FT KRM +IVR S G++ Y KGAD V +A +Y + + A EGLR
Sbjct: 548 EFTSARKRMSVIVRTPS-GKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRT 606
Query: 599 LVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQAD 658
L A ++E +Q++ A Y +A SV +R LK+ E +E ++LL T +ED+LQ
Sbjct: 607 LCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQ 666
Query: 659 VRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEA------ 712
V T+ETL A IK+W+LTGDK ETA + L+ +N + +V N G
Sbjct: 667 VPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGM----IVINEGSLDGTRET 722
Query: 713 ---HLEL--NAFRRKHDCALVISGDSLEVCLKY-YEYEFMELACQCPAVVCCRCAPTQKA 766
H +A R+++D AL+I G +L+ L + F++LA C AV+CCR +P QK+
Sbjct: 723 LSRHCTTLGDALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRVSPLQKS 782
Query: 767 QIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGR 826
++V +++++ +T A+GDG NDVSMIQ + GVG+ G EG QA+ ++D+SI QFK+L
Sbjct: 783 EVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKN 842
Query: 827 LLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTM 886
LLM+HG +Y R + + ++++ + ++ F+ V F+ L++ + I Y+ ++T
Sbjct: 843 LLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVMFTA 902
Query: 887 FPVFSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLL 945
P +L + ++ + E + YPELYK + K F + L ++ + + L
Sbjct: 903 MPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVILFWFPLKA 962
Query: 946 FE----------SEFVHIVAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYI 992
+ S+++ + +T +++T L L W W +A S+A ++
Sbjct: 963 LQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGSIALWV 1019
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 455 bits (1171), Expect = e-128
Identities = 319/1067 (29%), Positives = 524/1067 (49%), Gaps = 79/1067 (7%)
Query: 51 QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLG 110
Q++ N I + KY + F+P LF QF+ N YFL++ Q + + + T +PL
Sbjct: 37 QKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSPV-TSGLPLF 95
Query: 111 FVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVP 170
FV+ VT I++ E+ + D EVN + + G VK +S NI+VGD++ + K++ P
Sbjct: 96 FVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFP 155
Query: 171 ADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNI 230
AD++ L + +GSC + T LDGET+ K + V T L T A+L + + + ++P
Sbjct: 156 ADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEA 215
Query: 231 DIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGT-VVGVVLYTGRELRSVMNTSNP 289
D++ F+G I L E+ L G + + + GV +YTG E + +N +
Sbjct: 216 DLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSK 275
Query: 290 RSKIGLFDLEVNCLTKILFGALVVVSLVMVALQH-------FAGRWYLQ----------- 331
K + +N I L+ +++ L++ + WY Q
Sbjct: 276 SQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKI 335
Query: 332 ------IIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI------PGTVVRSSTIP 379
+ FL+L++ IIPISL V ++M K + S+ I D + V +S +
Sbjct: 336 LRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLN 395
Query: 380 EQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGL------------DSMDEVQSHIFS 427
E+LG++ Y+ TDKTGTLT+NEM F+ + + Y DS + S++ S
Sbjct: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSS 455
Query: 428 IYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAV-KAIALCHNVTPVYESNGVTDQAEAEK 486
+ + T+ T + H+ KA++LCH V T +
Sbjct: 456 LSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQS 515
Query: 487 QYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTY 546
S Y ASSPDE ALV+ +G+ +G + +M+++T G ++ + +L I F
Sbjct: 516 NLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLG-KLERYKLLHILEFDS 574
Query: 547 ESKRMGIIVRDESTGEITFYMKGAD--VVMAGIVQYNDWLEEECGNMAREGLRVLVVAKK 604
+ +RM +IV+ S GE + KGA+ ++ I + A +GLR L +A +
Sbjct: 575 DRRRMSVIVQAPS-GEKLLFAKGAESSILPKCIGGEIEKTRIHVDEFALKGLRTLCIAYR 633
Query: 605 SLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLE 664
++Y++ + R +A+ ++ R K+A V + +E ++ LL T VED+LQ VR T+E
Sbjct: 634 KFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIE 693
Query: 665 TLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKH- 723
LR AGIKVW+LTGDK ETA + + R +I + E +L R+
Sbjct: 694 ALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLARRIT 753
Query: 724 -----DCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGK 778
LV+ G SL + L+ +E FME+ C AV+CCR AP QKA+++RL++ K
Sbjct: 754 EDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEK 813
Query: 779 -LTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYK 837
+T AVGDG NDVSMIQE+ G+G+ GKEG+QA+ +D++I +FK L +LL VHG Y
Sbjct: 814 PITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYI 873
Query: 838 RSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDK 896
R A L Q+ ++++C T Q ++ F+ LY + Y+ +T P+ +L++
Sbjct: 874 RIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQ 933
Query: 897 DVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHI--- 953
V V P LY+D+ K R LS KTFL W ++ +G+ LL + +
Sbjct: 934 HVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNG 993
Query: 954 --------VAISFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVF----LHEF 1001
+ FT +++T + +AL W W+ + S+ Y +F L F
Sbjct: 994 QMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPF 1053
Query: 1002 I---DVYFI----ATLSFLWKVSVITLVSCLPLYVLKYLRRRFSPPS 1041
+ ++YF+ + W ++ +V+CL L ++K + R P+
Sbjct: 1054 LGSQNMYFVFIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPT 1100
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 454 bits (1169), Expect = e-127
Identities = 339/1118 (30%), Positives = 540/1118 (48%), Gaps = 122/1118 (10%)
Query: 29 RCCGGGE--ARPRTVWLGHPEKRD-------QRYPRNVINNQKYNFFTFLPGVLFNQFKY 79
R C G E RT+++GH E QRYP N I + KY F+ F+P LF QF+
Sbjct: 12 RYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRR 71
Query: 80 FFNLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVY 139
N YFL++ Q + + + T +PL FV+ VT I++ E+ + D +N
Sbjct: 72 VANFYFLIIFLVQLIIDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPV 130
Query: 140 SRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWK 199
+ V+ +S ++VGD+++V++++ P D+IFL ++ +G+C + T LDGE+ K
Sbjct: 131 HFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHK 190
Query: 200 LRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT-REDSDPPISESLSIENTL 258
V T+ T D+ + + + E+P D++ FVG D + P+ L EN L
Sbjct: 191 THYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLL 250
Query: 259 WAG-TVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLV 317
G T+ + + GV +YTG E + +N + K + +N + L+ +L+
Sbjct: 251 LRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALI 310
Query: 318 MVALQHFAGR-------WYLQ-----------------IIRFLLLFSNIIPISLRVNLDM 353
L++ WY Q + F++LF+ IIP+S+ V ++M
Sbjct: 311 NTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEM 370
Query: 354 GKIVYSWVIRRDSKI------PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLH 407
K + S+ I D + G +V +S + E+LG++ Y+ TDKTGTLT+N M FK
Sbjct: 371 QKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECC 430
Query: 408 LGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCH 467
+ Y + Q + + S P++ + R + R A+ LCH
Sbjct: 431 IEGHVYVPHVICNGQ-----VLPESSGIDMIDSSPSVNGREREELFFR------ALCLCH 479
Query: 468 NVTPVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLR 527
V + + D SC VY +SSPDEVALV+ + +G T + + M++
Sbjct: 480 TVQ--VKDDDSVDGPRKSPDGGKSC-VYISSSPDEVALVEGVQRLGFTYLRLKDNYMEIL 536
Query: 528 TPGDQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADV-----VMAGIVQYND 582
+ I F +L+I F +RM +IV+ +TGEI + KGAD V+ G V D
Sbjct: 537 NRENHIERFELLEILSFDSVRRRMSVIVKS-ATGEIYLFCKGADSSIFPRVIEGKV---D 592
Query: 583 WLEEECGNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEME 642
+ A EGLR L VA K L +E+Y+ AK+++ DR K+A E +E +
Sbjct: 593 QIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKD 652
Query: 643 MELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHV 702
+ LL T VED+LQ T+E L+ AGIKVW+LTGDK+ETA T L RN +
Sbjct: 653 LTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQL-- 710
Query: 703 FRLVTNRGEAH------LELNAFRRKH-----------------DCALVISGDSLEVCLK 739
L T R E EL+ +H D L+I G +L + +K
Sbjct: 711 LELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMK 770
Query: 740 --------YYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQ-ERTGKLTCAVGDGGNDV 790
Y F+E+ C AV+CCR AP QKAQIV+L++ + +T A+GDG NDV
Sbjct: 771 PREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDV 830
Query: 791 SMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRS 850
SMI E+ G+GV GKEG+QA+ +D++I +FKHL ++L+VHG Y R + L Q+ +++
Sbjct: 831 SMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKN 890
Query: 851 LCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPEL 909
+C Q ++ F+ LY + Y+ +T P+ ++++ V +V P L
Sbjct: 891 VCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTL 950
Query: 910 YKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFV----------HIVAISFT 959
Y+D+ K L ++ F+ W L+ ++ +GA +FE+ V + FT
Sbjct: 951 YRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFT 1010
Query: 960 SLILTELLMVALTIQTWHWLMTVAELLSLACYIA-SLV-------FL-HEFIDVYFIATL 1010
++ T L +AL W W+ SL Y+ SL+ FL ++ + FI L
Sbjct: 1011 VMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQML 1070
Query: 1011 SF--LW-KVSVITLVSCLPLYVLKYLRRRFSPPSYSKL 1045
S W + ++ +S LP + K L R+ P + ++
Sbjct: 1071 SSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERV 1108
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 454 bits (1169), Expect = e-127
Identities = 339/1118 (30%), Positives = 540/1118 (48%), Gaps = 122/1118 (10%)
Query: 29 RCCGGGE--ARPRTVWLGHPEKRD-------QRYPRNVINNQKYNFFTFLPGVLFNQFKY 79
R C G E RT+++GH E QRYP N I + KY F+ F+P LF QF+
Sbjct: 12 RYCAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRR 71
Query: 80 FFNLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVY 139
N YFL++ Q + + + T +PL FV+ VT I++ E+ + D +N
Sbjct: 72 VANFYFLIIFLVQLIIDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPV 130
Query: 140 SRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWK 199
+ V+ +S ++VGD+++V++++ P D+IFL ++ +G+C + T LDGE+ K
Sbjct: 131 HFIQHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHK 190
Query: 200 LRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT-REDSDPPISESLSIENTL 258
V T+ T D+ + + + E+P D++ FVG D + P+ L EN L
Sbjct: 191 THYAVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLL 250
Query: 259 WAG-TVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLV 317
G T+ + + GV +YTG E + +N + K + +N + L+ +L+
Sbjct: 251 LRGATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALI 310
Query: 318 MVALQHFAGR-------WYLQ-----------------IIRFLLLFSNIIPISLRVNLDM 353
L++ WY Q + F++LF+ IIP+S+ V ++M
Sbjct: 311 NTVLKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEM 370
Query: 354 GKIVYSWVIRRDSKI------PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLH 407
K + S+ I D + G +V +S + E+LG++ Y+ TDKTGTLT+N M FK
Sbjct: 371 QKFLGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECC 430
Query: 408 LGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCH 467
+ Y + Q + + S P++ + R + R A+ LCH
Sbjct: 431 IEGHVYVPHVICNGQ-----VLPESSGIDMIDSSPSVNGREREELFFR------ALCLCH 479
Query: 468 NVTPVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLR 527
V + + D SC VY +SSPDEVALV+ + +G T + + M++
Sbjct: 480 TVQ--VKDDDSVDGPRKSPDGGKSC-VYISSSPDEVALVEGVQRLGFTYLRLKDNYMEIL 536
Query: 528 TPGDQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADV-----VMAGIVQYND 582
+ I F +L+I F +RM +IV+ +TGEI + KGAD V+ G V D
Sbjct: 537 NRENHIERFELLEILSFDSVRRRMSVIVKS-ATGEIYLFCKGADSSIFPRVIEGKV---D 592
Query: 583 WLEEECGNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEME 642
+ A EGLR L VA K L +E+Y+ AK+++ DR K+A E +E +
Sbjct: 593 QIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKD 652
Query: 643 MELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHV 702
+ LL T VED+LQ T+E L+ AGIKVW+LTGDK+ETA T L RN +
Sbjct: 653 LTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQL-- 710
Query: 703 FRLVTNRGEAH------LELNAFRRKH-----------------DCALVISGDSLEVCLK 739
L T R E EL+ +H D L+I G +L + +K
Sbjct: 711 LELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMK 770
Query: 740 --------YYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQ-ERTGKLTCAVGDGGNDV 790
Y F+E+ C AV+CCR AP QKAQIV+L++ + +T A+GDG NDV
Sbjct: 771 PREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDV 830
Query: 791 SMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRS 850
SMI E+ G+GV GKEG+QA+ +D++I +FKHL ++L+VHG Y R + L Q+ +++
Sbjct: 831 SMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKN 890
Query: 851 LCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPEL 909
+C Q ++ F+ LY + Y+ +T P+ ++++ V +V P L
Sbjct: 891 VCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTL 950
Query: 910 YKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFV----------HIVAISFT 959
Y+D+ K L ++ F+ W L+ ++ +GA +FE+ V + FT
Sbjct: 951 YRDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFT 1010
Query: 960 SLILTELLMVALTIQTWHWLMTVAELLSLACYIA-SLV-------FL-HEFIDVYFIATL 1010
++ T L +AL W W+ SL Y+ SL+ FL ++ + FI L
Sbjct: 1011 VMVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQML 1070
Query: 1011 SF--LW-KVSVITLVSCLPLYVLKYLRRRFSPPSYSKL 1045
S W + ++ +S LP + K L R+ P + ++
Sbjct: 1071 SSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERV 1108
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 445 bits (1144), Expect = e-124
Identities = 327/1108 (29%), Positives = 528/1108 (47%), Gaps = 126/1108 (11%)
Query: 31 CGGGEAR--PRTVWLG-HPEKRD-----QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFN 82
C G E R RTV++G HP QR+ N I + KY + FLP LF QF+ N
Sbjct: 13 CAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIAN 72
Query: 83 LYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRL 142
YFL++ Q + + T +PL FV+ VT I++ E+ + D EVN +
Sbjct: 73 FYFLIIFLVQVTVDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYII 131
Query: 143 TARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRL 202
V+ +S I+VGD++ V+ ++ P D+I L + +G+C++ T LDGE++ K
Sbjct: 132 ENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHY 191
Query: 203 PVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT-REDSDPPISESLSIENTLWAG 261
V T L TA + +R+ + E+P D++ FVG +S ++ SL EN L G
Sbjct: 192 AVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKG 251
Query: 262 -TVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA 320
T+ + + GV +YTG E + +N K + +N + L+ + V
Sbjct: 252 ATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTT 311
Query: 321 LQHFAGR-------WYLQ-----------------IIRFLLLFSNIIPISLRVNLDMGKI 356
L++ WY Q + F++LF+ IIP+S+ V ++M K
Sbjct: 312 LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKF 371
Query: 357 VYSWVIRRDSKI------PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGT 410
+ S+ I D G +V +S + E+LG++ Y+ TDKTGTLT+N M F
Sbjct: 372 LGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECC--- 428
Query: 411 VAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVT 470
+ H + TQ+ D +Q TLT + +R ++A+ LCH V
Sbjct: 429 ----------IDGHKYKGVTQEV-DGLSQTDGTLTY-FDKVDKNREELFLRALCLCHTVE 476
Query: 471 PVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPG 530
++N D A E + Y +SSPDE+ALV+ + G T +G M++
Sbjct: 477 --IKTNDAVDGAT-----ESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQR 529
Query: 531 DQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYND--WLEEEC 588
+I + +L F +RM +IV+ + G+I + KGAD + VQ ++ +
Sbjct: 530 KEIEEYELLHTLNFDAVRRRMSVIVKTQE-GDILLFCKGADSAVFPRVQNHEIELTKVHV 588
Query: 589 GNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCL 648
A +G R L VA K +A + Y+ + ++AK+++ DR K+ V + +E M L+
Sbjct: 589 ERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGA 648
Query: 649 TGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVT- 707
T VED+LQ T+E L AG+KVW+LTGDK+ETA T L N ++ T
Sbjct: 649 TAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTI 708
Query: 708 -----NRGEAHLELNAFRRK-------------------HDCALVISGDSLEVCLKY--- 740
H L +R+K + L+I G +L + L
Sbjct: 709 EESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQD 768
Query: 741 -----YEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGK-LTCAVGDGGNDVSMIQ 794
Y+ F+++ +C AV+CCR AP QKAQIVR+++ G +T ++GDG NDVSMI
Sbjct: 769 SSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMIL 828
Query: 795 ESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCIS 854
ES G+G++GKEG+QA+ +D+S+ +FKHL +LL+ HG Y R A L Q+ +++LC
Sbjct: 829 ESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFI 888
Query: 855 TMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELYKDL 913
Q ++ F+ PLY + Y+ +T P+ + +L++ + + P LY +
Sbjct: 889 LPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKI 948
Query: 914 LKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVH----------IVAISFTSLIL 963
L FL W ++ ++G+ +G LF++ + I FT L+
Sbjct: 949 SGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVF 1008
Query: 964 TELLMVALTIQTWHWLMTVAELLSLACYI------ASLV--FLHE----FIDVYFIATLS 1011
T L +AL + W W+ SLA Y+ ++ FL + F+ ++++S
Sbjct: 1009 TVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVS 1068
Query: 1012 FLWKVSVITLVSCLP---LYVLKYLRRR 1036
+ ++ +S P L VLK +RRR
Sbjct: 1069 TWLAIILLIFISLFPEILLIVLKNVRRR 1096
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 445 bits (1144), Expect = e-124
Identities = 327/1108 (29%), Positives = 528/1108 (47%), Gaps = 126/1108 (11%)
Query: 31 CGGGEAR--PRTVWLG-HPEKRD-----QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFN 82
C G E R RTV++G HP QR+ N I + KY + FLP LF QF+ N
Sbjct: 13 CAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIAN 72
Query: 83 LYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRL 142
YFL++ Q + + T +PL FV+ VT I++ E+ + D EVN +
Sbjct: 73 FYFLIIFLVQVTVDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYII 131
Query: 143 TARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRL 202
V+ +S I+VGD++ V+ ++ P D+I L + +G+C++ T LDGE++ K
Sbjct: 132 ENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHY 191
Query: 203 PVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT-REDSDPPISESLSIENTLWAG 261
V T L TA + +R+ + E+P D++ FVG +S ++ SL EN L G
Sbjct: 192 AVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKG 251
Query: 262 -TVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA 320
T+ + + GV +YTG E + +N K + +N + L+ + V
Sbjct: 252 ATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTT 311
Query: 321 LQHFAGR-------WYLQ-----------------IIRFLLLFSNIIPISLRVNLDMGKI 356
L++ WY Q + F++LF+ IIP+S+ V ++M K
Sbjct: 312 LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKF 371
Query: 357 VYSWVIRRDSKI------PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGT 410
+ S+ I D G +V +S + E+LG++ Y+ TDKTGTLT+N M F
Sbjct: 372 LGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECC--- 428
Query: 411 VAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVT 470
+ H + TQ+ D +Q TLT + +R ++A+ LCH V
Sbjct: 429 ----------IDGHKYKGVTQEV-DGLSQTDGTLTY-FDKVDKNREELFLRALCLCHTVE 476
Query: 471 PVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPG 530
++N D A E + Y +SSPDE+ALV+ + G T +G M++
Sbjct: 477 --IKTNDAVDGAT-----ESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQR 529
Query: 531 DQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYND--WLEEEC 588
+I + +L F +RM +IV+ + G+I + KGAD + VQ ++ +
Sbjct: 530 KEIEEYELLHTLNFDAVRRRMSVIVKTQE-GDILLFCKGADSAVFPRVQNHEIELTKVHV 588
Query: 589 GNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCL 648
A +G R L VA K +A + Y+ + ++AK+++ DR K+ V + +E M L+
Sbjct: 589 ERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGA 648
Query: 649 TGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVT- 707
T VED+LQ T+E L AG+KVW+LTGDK+ETA T L N ++ T
Sbjct: 649 TAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTI 708
Query: 708 -----NRGEAHLELNAFRRK-------------------HDCALVISGDSLEVCLKY--- 740
H L +R+K + L+I G +L + L
Sbjct: 709 EESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQD 768
Query: 741 -----YEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGK-LTCAVGDGGNDVSMIQ 794
Y+ F+++ +C AV+CCR AP QKAQIVR+++ G +T ++GDG NDVSMI
Sbjct: 769 SSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMIL 828
Query: 795 ESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCIS 854
ES G+G++GKEG+QA+ +D+S+ +FKHL +LL+ HG Y R A L Q+ +++LC
Sbjct: 829 ESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFI 888
Query: 855 TMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELYKDL 913
Q ++ F+ PLY + Y+ +T P+ + +L++ + + P LY +
Sbjct: 889 LPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKI 948
Query: 914 LKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVH----------IVAISFTSLIL 963
L FL W ++ ++G+ +G LF++ + I FT L+
Sbjct: 949 SGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVF 1008
Query: 964 TELLMVALTIQTWHWLMTVAELLSLACYI------ASLV--FLHE----FIDVYFIATLS 1011
T L +AL + W W+ SLA Y+ ++ FL + F+ ++++S
Sbjct: 1009 TVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVS 1068
Query: 1012 FLWKVSVITLVSCLP---LYVLKYLRRR 1036
+ ++ +S P L VLK +RRR
Sbjct: 1069 TWLAIILLIFISLFPEILLIVLKNVRRR 1096
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 439 bits (1128), Expect = e-123
Identities = 299/1003 (29%), Positives = 496/1003 (49%), Gaps = 92/1003 (9%)
Query: 35 EARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFV 94
EA RT++L P ++ N I+ KY+ TFLP L+ Q + N +FL +A Q +
Sbjct: 52 EAPARTIYLNQPHLN--KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQI 109
Query: 95 PEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSN 154
P++ YT VPL +L + I+E VE+ + + D VN + L +
Sbjct: 110 PDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKE 169
Query: 155 IQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAA 214
+ VGD++ V Q +PAD++ L +SE C++ T LDGET+ K+R ++ T + T
Sbjct: 170 VAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTRE 229
Query: 215 DLLQIRSYVYAEEPNIDIHNFVGTFTREDS-------DPPISESLSIENTLWAGTVVASG 267
L+++ + E PN +++F G + D + + NT W
Sbjct: 230 VLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQW-------- 281
Query: 268 TVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA------L 321
V G+V+YTG + + + N++ K + N +LFG L+V++LV A
Sbjct: 282 -VFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNR 340
Query: 322 QHFAGRWYLQ------------IIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI- 368
H WY++ ++ F++L++N+IPISL V L++ K + I D+ +
Sbjct: 341 SHGEKNWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMY 400
Query: 369 -----PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGL--DSMDEV 421
+ R+S + E+LG++ YL +DKTGTLT N M FK+ + V YG + E
Sbjct: 401 YIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREP 460
Query: 422 QSHIFSIYTQQSQDPPAQKGPTLTTKV--RRTMSSRVHEAVKAIALCHNVTPVYESNGVT 479
S F D P L + R + + E + +A+CH V P + + +
Sbjct: 461 SSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNI- 519
Query: 480 DQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTIL 539
+YQASSPDE ALV+ + +G R S+ + G + F IL
Sbjct: 520 --------------IYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQE-QTFGIL 564
Query: 540 QIFPFTYESKRMGIIVRDESTGEITFYMKGAD-VVMAGIVQYNDWLEEECGNM---AREG 595
+ F+ + KRM +IVR S G + Y KGAD V+ + + + ++EE ++ A EG
Sbjct: 565 NVLEFSSDRKRMSVIVRTPS-GRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYFATEG 623
Query: 596 LRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQL 655
LR L VA L+E +Y+++ Y +A + DR+ ++ E +E + LL T +ED+L
Sbjct: 624 LRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRL 683
Query: 656 QADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFR---LVTNRGEA 712
QA V T+ TL A IK+W+LTGDK ETA + LV++N + + + L R
Sbjct: 684 QAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAI 743
Query: 713 HLEL----NAFRRKHDCALVISGDSLEVCLKY-YEYEFMELACQCPAVVCCRCAPTQKAQ 767
N +++D AL+I G +L+ L + F++LA C AV+CCR +P QK++
Sbjct: 744 TQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSE 803
Query: 768 IVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRL 827
IV ++++R +T A+GDG NDV MIQ + GVG+ G EG QA+ +D++I QF +L +L
Sbjct: 804 IVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKL 863
Query: 828 LMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMF 887
L+VHG SY R + ++++ + ++ F+ V F+ L++ + I Y+ I+T
Sbjct: 864 LLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTAL 923
Query: 888 PVFSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTF-------------LIWVLISIY 933
P F+L + ++ E + +P+LYK G + K F L W +
Sbjct: 924 PPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWFPMKAL 983
Query: 934 QGSTIMYGALLLFESEFVHIVAISFTSLILTELLMVALTIQTW 976
+ T++ ++++ + I +T +++T L L W
Sbjct: 984 EHDTVLTSG---HATDYLFVGNIVYTYVVVTVCLKAGLETTAW 1023
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 437 bits (1123), Expect = e-122
Identities = 335/1100 (30%), Positives = 530/1100 (48%), Gaps = 146/1100 (13%)
Query: 52 RYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGF 111
+Y N I KYN TFLP LF QF+ N YFL L Q +P++ + +T VPL
Sbjct: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
Query: 112 VLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKS-SNIQVGDLIIVEKNQRVP 170
VL +T +++A ++ + D +VN++ S++ G ++ + N+ VGD+I +E NQ V
Sbjct: 121 VLTITAVKDATDDYFRHKSDNQVNNR-QSQVLINGILQQEQWMNVCVGDIIKLENNQFVA 179
Query: 171 ADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNI 230
AD++ L +SE +G C++ T +LDGET+ K+R + T L + L + V E PN
Sbjct: 180 ADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNN 239
Query: 231 DIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGT-VVGVVLYTGRELRSVMNTSNP 289
+ F GT +++ P+S +N L G V+ + G+V++ G + + + N+
Sbjct: 240 KLDKFSGTLYWKENKFPLSN----QNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295
Query: 290 RSKIGLFDLEVNCLTKILFGALVVVSLVMVA----LQHFAGR-------W---------- 328
+ K D +N L +FG LV + +++ +H G W
Sbjct: 296 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS 355
Query: 329 -YLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI------PGTVVRSSTIPEQ 381
+L ++++ + ++PISL V++++ ++ +S+ I D K+ R++T+ E+
Sbjct: 356 GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEE 415
Query: 382 LGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQ-----SQDP 436
LG++ Y+ +DKTGTLTQN M+F + + +YG + +V H + + S +P
Sbjct: 416 LGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYG--DVFDVLGHKAELGERPEPVDFSFNP 473
Query: 437 PAQK-----GPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDS 491
A K P+L V+ HE + ++LCH V ++ G
Sbjct: 474 LADKKFLFWDPSLLEAVK-IGDPHTHEFFRLLSLCHTVMSEEKNEGEL------------ 520
Query: 492 CRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRM 551
Y+A SPDE ALV + G R ++ + G I + +L I F KRM
Sbjct: 521 --YYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAI-TYQLLAILDFNNIRKRM 577
Query: 552 GIIVRDESTGEITFYMKGADVVMAGIVQYN---------DWLEEECGNMAREGLRVLVVA 602
+IVR+ G+I Y KGAD ++ + ++ D L E G EGLR LV+A
Sbjct: 578 SVIVRNPE-GKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAG----EGLRTLVLA 632
Query: 603 KKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPT 662
K L EE Y+++ R +QA L+ R ++A++ E +E M LL T +ED+LQ V T
Sbjct: 633 YKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPET 692
Query: 663 LETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRG--EAHLELNAFR 720
+ L A IK+W+LTGDK ETA + ++T D+ +VT E EL R
Sbjct: 693 IALLTLANIKIWVLTGDKQETAVNIGYSCKMLT--DDMTEVFIVTGHTVLEVREELRKAR 750
Query: 721 RKH-------------------------------DCALVISGDSLEVCLKY-YEYEFMEL 748
K + ALVI+G SL L+ E EF+E
Sbjct: 751 EKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELEFLET 810
Query: 749 ACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGK 808
AC C AV+CCR P QKAQ+V L+++ +T A+GDG NDVSMI+ + GVG+ G+EG
Sbjct: 811 ACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGI 870
Query: 809 QASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFAS 868
QA LA+D+S +QFK L RLL+VHGR SY R + +++ + + F F++
Sbjct: 871 QAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSA 930
Query: 869 VPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIW 927
+Y + I Y+ +YT PV ++ V D+DV + +M YP+LY+ + + F I
Sbjct: 931 QTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFIC 990
Query: 928 VLISIYQGSTIMY--------------GALLLFESEFVHIVAISFTSLILTELLMVALTI 973
+ IY S +M+ G L F VA TSL++ + + L
Sbjct: 991 IAQGIYT-SVLMFFIPYGVFADATRDDGTQLADYQSFAVTVA---TSLVIVVSVQIGLDT 1046
Query: 974 QTWHWLMTVAELLSLACYIASLVFLHE--FIDVY-----FIATLS------FLWKVSVIT 1020
W + SLA Y A L +H D++ F+ +W V+T
Sbjct: 1047 GYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLT 1106
Query: 1021 LVSC-LPLYVLKYLRRRFSP 1039
V C +P+ ++LR P
Sbjct: 1107 TVVCIMPVVAFRFLRLNLKP 1126
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 421 bits (1083), Expect = e-117
Identities = 317/1090 (29%), Positives = 527/1090 (48%), Gaps = 134/1090 (12%)
Query: 52 RYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGF 111
+Y N I+ KYN TFLP LF QF+ N YFL L Q +PE+ +T VPL
Sbjct: 27 QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
Query: 112 VLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPA 171
V+ +T +++A ++ + D +VN++ L K N++VGD+I +E NQ V A
Sbjct: 87 VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
Query: 172 DMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSY---VYAEEP 228
D++ L +SE +G C++ T +LDGET+ K+R ++ T L AD+ ++ + V E P
Sbjct: 147 DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSEL--GADISRLAGFDGIVVCEVP 204
Query: 229 NIDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGT-VVGVVLYTGRELRSVMNTS 287
N + F+G + +DS SL+ E + G ++ + + G+V++ G + + + N+
Sbjct: 205 NNKLDKFMGILSWKDS----KHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSG 260
Query: 288 NPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQH------------------------ 323
+ K D +N L +FG L+ + +++
Sbjct: 261 KTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGEKSSV 320
Query: 324 FAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSK-------IPGTVVRSS 376
F+G +L ++++ + ++PISL V++++ ++ +S+ I D K IP V R++
Sbjct: 321 FSG--FLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPA-VARTT 377
Query: 377 TIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYG-----LDSMDEVQSHI----FS 427
T+ E+LG+I Y+ +DKTGTLTQN M FKR + YG LD E+ FS
Sbjct: 378 TLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFS 437
Query: 428 IYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQ 487
+ +Q ++ Q + + +VHE ++ +ALCH V S G
Sbjct: 438 VKSQADRE--FQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGEL-------- 487
Query: 488 YEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYE 547
+YQ SPDE ALV + G R ++ + G ++ + +L F
Sbjct: 488 ------IYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGT-LVTYQLLAFLDFNNT 540
Query: 548 SKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWL-----EEECGNMAREGLRVLVVA 602
KRM +IVR+ G+I Y KGAD ++ + ++ + + A EGLR L +A
Sbjct: 541 RKRMSVIVRNPE-GQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIA 599
Query: 603 KKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPT 662
+ L ++ ++++ A + +R ++A + E +E ++ LL T VED+LQ V T
Sbjct: 600 YRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIET 659
Query: 663 LETLRNAGIKVWMLTGDKLETATCTAKNAHLVT---------------------RNQDIH 701
+ +L A IK+W+LTGDK ETA +++T R +
Sbjct: 660 VTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQN 719
Query: 702 VFRLVTNRGEAH--------LELNAFRRKH---DCALVISGDSLEVCLKY-YEYEFMELA 749
+F N H LEL++ + D AL+I+G SL L+ + + +ELA
Sbjct: 720 LFGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVKNDLLELA 779
Query: 750 CQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQ 809
C C V+CCR P QKAQ+V L+++ +T A+GDG NDVSMI+ + GVG+ G+EG Q
Sbjct: 780 CMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQ 839
Query: 810 ASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASV 869
A LA+D+S QF++L RLL+VHGR SY R + +++ + + F F++
Sbjct: 840 AVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQ 899
Query: 870 PLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWV 928
+Y + I ++ +YT PV ++ + D+DV + ++ P+LYK + + F I V
Sbjct: 900 TVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICV 959
Query: 929 LISIYQGST---IMYGALLLFESE-------FVHIVAISFTSLILTELLMVALTIQTWHW 978
L IY I YGA E + TSL++ + +AL W +
Sbjct: 960 LHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTF 1019
Query: 979 LMTVAELLSLACYIASLVFLHE------------FI-DVYFIATLSFLWKVSVITLV-SC 1024
+ V S+A Y + L +H F+ + T +W V ++T V S
Sbjct: 1020 INHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASV 1079
Query: 1025 LPLYVLKYLR 1034
+P+ ++L+
Sbjct: 1080 MPVVAFRFLK 1089
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 411 bits (1057), Expect = e-114
Identities = 321/1119 (28%), Positives = 529/1119 (47%), Gaps = 150/1119 (13%)
Query: 49 RDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVP 108
++ +Y N I KYN FTF+P LF QFK NLYFL L Q VP++ A YT VP
Sbjct: 88 KESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVP 147
Query: 109 LGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKV-KSSNIQVGDLIIVEKNQ 167
L VL VT I++ V+++ + DKE+N++ + G KV K IQVGD+I ++KN
Sbjct: 148 LLVVLGVTAIKDLVDDVARHKMDKEINNRT-CEVIKDGRFKVAKWKEIQVGDVIRLKKND 206
Query: 168 RVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACT-QRLPTAADLLQIRSYVYAE 226
VPAD++ L +SE N C++ T +LDGET+ K ++ + T Q L L ++ E
Sbjct: 207 FVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECE 266
Query: 227 EPNIDIHNFVGT-FTREDSDPPISESLSIENTLWAGTVVASGTVV-GVVLYTGRELRSVM 284
EPN + F GT F R S P L + L G V+ + G+V++ G + + +
Sbjct: 267 EPNNRLDKFTGTLFWRNTSFP-----LDADKILLRGCVIRNTDFCHGLVIFAGADTKIMK 321
Query: 285 NTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMV------ALQHFAGRWYLQ------- 331
N+ R K D +N + +F L+++S + Q WYL
Sbjct: 322 NSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTP 381
Query: 332 -------IIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRD------SKIPGTVVRSSTI 378
++++ + ++PISL V++++ ++ S I D K R++T+
Sbjct: 382 SYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441
Query: 379 PEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSI------YTQQ 432
EQLG+I Y+ +DKTGTLTQN M FK+ + YG D D Q + I +
Sbjct: 442 NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYG-DHRDASQHNHNKIEQVDFSWNTY 500
Query: 433 SQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSC 492
+ A L +++ V + +A+CH V + D+ + +
Sbjct: 501 ADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTV--------MVDRTDGQLN----- 547
Query: 493 RVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRMG 552
YQA+SPDE ALV + G + R Q+++ + G + + +L I F + KRM
Sbjct: 548 --YQAASPDEGALVNAARNFGFAFLARTQNTITISELGTE-RTYNVLAILDFNSDRKRMS 604
Query: 553 IIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGN----MAREGLRVLVVAKKSLAE 608
IIVR G I Y KGAD V+ + + ++E + A E LR L + K + E
Sbjct: 605 IIVRTPE-GNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEE 663
Query: 609 EQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRN 668
+++ ++ +++ A ++ +R + V E +E ++ LL T +ED+LQ V T+ L
Sbjct: 664 KEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAK 723
Query: 669 AGIKVWMLTGDKLETATCTAKNAHLVTRN------QDIHV-----FRLVTNRGEAH---- 713
A IK+W+LTGDK ETA L+T + +DI+ NRG +
Sbjct: 724 ADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGVYAKFA 783
Query: 714 --LELNAFRRKHDCALVISGD------------------------------------SLE 735
++ + F + AL+I+G LE
Sbjct: 784 PPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKRRLE 843
Query: 736 VCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQE 795
+ + F++LAC+C AV+CCR P QKA +V L++ +T A+GDG NDV+MI+
Sbjct: 844 AKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKT 903
Query: 796 SDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCIST 855
+ GVG+ G+EG QA +++D+S QF++L RLL+VHGR SY R ++ +++ +
Sbjct: 904 AHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTL 963
Query: 856 MQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELY---- 910
+ +S +++ Y+ + I Y+ +YT PV + +LD+DV ++++ +P LY
Sbjct: 964 VHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQ 1023
Query: 911 KDLLKGRPLSYKTFLIWVLISIYQGSTIMY---GALLL-------FESEFVHIVAISFTS 960
+DLL +YK F + +L + + + GA L S++ ++
Sbjct: 1024 RDLL----FNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASA 1079
Query: 961 LILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEF-IDVYFIATLSF------- 1012
L++T + L W ++ + S+A Y + H I V F + F
Sbjct: 1080 LVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNA 1139
Query: 1013 -----LWKVSVITLVSC-LPLYVLKYLRRRFSPPSYSKL 1045
+W ++T+ C LP+ +++L P K+
Sbjct: 1140 LRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKI 1178
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 335 bits (858), Expect = 2e-91
Identities = 298/1113 (26%), Positives = 511/1113 (45%), Gaps = 163/1113 (14%)
Query: 51 QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLG 110
++Y NVI KYNF++FLP L+ QF NL+FL++ Q +P++ ++ P+
Sbjct: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
Query: 111 FVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVP 170
+L + R+ V+++ + D+ +N++ L + + K ++ VGD++ + K+ VP
Sbjct: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
Query: 171 ADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQR-LPTAADLLQIRSYVYAEEPN 229
ADM+ L ++E + C++ T +DGET+ K R + T + L T + + V E PN
Sbjct: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
Query: 230 IDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVA-SGTVVGVVLYTGRELRSVMNTSN 288
+H+FVG D SL I N L G + + T G+V+Y G + + + N
Sbjct: 311 SRMHHFVGCLEWNDK----KYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGK 366
Query: 289 PRSKIGLFDLEVNCLTKILFGALVVVSLVMV-----ALQHFAG-RWYLQIIR-------- 334
K DL +N L ++F ++V+V LV+ +++ F +YL +
Sbjct: 367 IHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAES 426
Query: 335 ------FLLLFSNIIPISLRVNLD---MGKIVY-SWVIR---RDSKIPGTVVRSSTIPEQ 381
FL+L S IP+S+ + + +G V+ W ++ + +P RS+++ +
Sbjct: 427 FFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAK-ARSTSLNDH 485
Query: 382 LGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQ-SHIFSIYTQQSQDPPAQK 440
LG++ Y+ +DKTGTLTQN + F + + YG DS + ++ + +
Sbjct: 486 LGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGKLLFH 545
Query: 441 GPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQASSP 500
L VR V E + +A+CH V E+ ++ D +YQA+SP
Sbjct: 546 NAALLHLVRTNGDEAVREFWRLLAICHTVM----------VRESPRERPDQL-LYQAASP 594
Query: 501 DEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRMGIIVRDEST 560
DE ALV + G + R Q ++ + G++ + + +L I F KRM ++VR +
Sbjct: 595 DEGALVTAARNFGYVFLSRTQDTVTIMELGEERV-YQVLAIMDFNSTRKRMSVLVR-KPE 652
Query: 561 GEITFYMKGADVVM------AGIVQYNDWLEEECGNMAREGLRVLVVAKKSLAEEQYQDF 614
G I Y KGAD V+ G +++ EE A+E LR L +A + +AE+ Y+D+
Sbjct: 653 GAICLYTKGADTVIFERLHRRGAMEFA--TEEALAAFAQETLRTLCLAYREVAEDIYEDW 710
Query: 615 EARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVW 674
+ R+ +A L + +R+ + +LL T +ED+LQ V T++ L+ + IK+W
Sbjct: 711 QQRHQEASLLLQNRA----------QALQQLLGATAIEDRLQDGVPETIKCLKKSNIKIW 760
Query: 675 MLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLE--LNAFRRKH----DCALV 728
+LTGDK ETA L++ N I + ++ E + E N R+ ALV
Sbjct: 761 VLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALV 820
Query: 729 ISGDSLEVCLKYYEYEFMELA---------------------CQCPAVVCCR------CA 761
I+GD L+ L E LA + +++C R
Sbjct: 821 INGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLSLLCRRFGLPLAAP 880
Query: 762 PTQKAQIVR---LLQERT---------GKLTCAV-----------------------GDG 786
P Q ++ R +LQER + C V GDG
Sbjct: 881 PAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVTLAIGDG 940
Query: 787 GNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFV 846
ND++MI+ +D GVG+ G+EG QA +DF + QF L RLL+VHGR SY R ++
Sbjct: 941 ANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYF 1000
Query: 847 IHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAML 905
++S+ +Q F+ F PLY+G+ + ++ +Y+ PV + + ++DV +E ++
Sbjct: 1001 FYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLE 1060
Query: 906 YPELYKDLLKGRPLSYKTF-----------LIWVLISIYQGSTIMYGALLLFESEFVHIV 954
PELY K +Y F L+ ++++ A F +V
Sbjct: 1061 KPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSFAVVV 1120
Query: 955 AISFTSLILTELLMVALTIQTWHWLMTVAELLSLACY--------------IASLVFLHE 1000
A+ S +L+ + V L I+ W L LLSL Y ++ F
Sbjct: 1121 AL---SCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPFL 1177
Query: 1001 FIDVYFIATLSFLWKVSVITLVSCLPLYVLKYL 1033
+ D+ +++ S L V + ++ P+ L+ +
Sbjct: 1178 YADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 265 bits (678), Expect = 1e-70
Identities = 188/586 (32%), Positives = 291/586 (49%), Gaps = 63/586 (10%)
Query: 472 VYESNGVTDQAEA-EKQYEDSCR---VYQASSPDEVALVQWTESVGLTLVGRDQSSMQLR 527
+ ES T EA E D R Y+A SPDE ALV + TLV R + +R
Sbjct: 690 ILESGSGTSLEEALEAPATDLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVR 749
Query: 528 TPGDQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQ-------- 579
P L F++L F KRM ++VR TGEI Y KGAD V+ +++
Sbjct: 750 LPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDI 809
Query: 580 --------YNDWLEEECGNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLK 631
++ AR+GLR L +AKK ++EE ++ + + +A+ S+ +R
Sbjct: 810 NMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDEL 869
Query: 632 VATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNA 691
+ + LE ++ LL TG+ED+LQ V T+ TLR AGI++W+LTGDK ETA A +
Sbjct: 870 LMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSC 929
Query: 692 HLVTRNQDIHVFRLVTNRGE--------AHLELNAFRRKH-------------------- 723
L+ NQ V+ + T E A EL FR
Sbjct: 930 RLL--NQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITS 987
Query: 724 -----DCALVISGDSLEVCLK-YYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTG 777
+ LVI G +L + E +F+EL C +V+CCR P QK+ IV+L++++
Sbjct: 988 EAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLR 1047
Query: 778 KLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYK 837
+T ++GDG NDVSMIQ +D G+G+ G+EG QA +++DF+IT+FKHL +LL+VHG Y
Sbjct: 1048 VMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYS 1107
Query: 838 RSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFP--VFSLVLD 895
R A + + +++++C + + F+S + + +I ++ +T P VF VLD
Sbjct: 1108 RLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFG-VLD 1166
Query: 896 KDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIVA 955
KD+ +E + PELYK + TF I ++ + YQ + L ++ + +
Sbjct: 1167 KDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFT 1226
Query: 956 ISF---TSLILTELLMVALTIQTWHWLMTVAELLSLACY-IASLVF 997
T + T LL A+ ++TW V L S Y + SL++
Sbjct: 1227 FGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLY 1272
Score = 169 bits (429), Expect = 1e-41
Identities = 131/459 (28%), Positives = 212/459 (46%), Gaps = 54/459 (11%)
Query: 47 EKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYW 106
E+ +RYP N KY FTFLP LF QF + NLYFL L ++P M +
Sbjct: 60 EEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITM 119
Query: 107 VPLGFVLAVTVIREAVEEIRCYVRDKEVNS---QVYSRLTARGTVKVKSSNIQVGDLIIV 163
+PL VL V +I++ +E+ + + DK +N ++Y R + V+ +++VGD I +
Sbjct: 120 LPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYER-KEQTYVQKCWKDVRVGDFIQM 178
Query: 164 EKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYV 223
+ N+ VPAD++ L +S+ NG C L T LDGET+ K R V + + + +
Sbjct: 179 KCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTI 238
Query: 224 YAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAG-TVVASGTVVGVVLYTGRELRS 282
E+PN ++ F G D E+ L G T+ + VG+V+Y G E ++
Sbjct: 239 VCEKPNNHLNKFKGYMEHPDQ---TRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKA 295
Query: 283 VMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA---------------------- 320
++N S PR K + +N G L+++ L+
Sbjct: 296 MLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANG 355
Query: 321 --LQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI------PGTV 372
L G +Y+ + ++L +IPISL V++++ K+ + + D +
Sbjct: 356 SFLPSALGGFYM-FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQ 414
Query: 373 VRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYG-------------LDSMD 419
R+ I E LG+I Y+ +DKTGTLT+N+M+F+R + Y LDS
Sbjct: 415 CRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDG 474
Query: 420 E--VQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRV 456
E Q S + +QDP + +RR+ S+RV
Sbjct: 475 EEWTQYQCLSFSARWAQDPATMRSQKGAQPLRRSQSARV 513
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 251 bits (641), Expect = 3e-66
Identities = 185/657 (28%), Positives = 314/657 (47%), Gaps = 76/657 (11%)
Query: 415 LDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRV---HEAVKAIALCHNVTP 471
+ S++E++S ++S P G ++ V SR+ A + V+
Sbjct: 619 IKSLEEIKSLFQRWSVRRSSSPSLNSGKEPSSGVPNAFVSRLPLFSRMKPASPVEEEVSQ 678
Query: 472 VYESNGVTDQA----EAEKQYEDS----------------CRV-YQASSPDEVALVQWTE 510
V ES + + E EKQ+ D+ C + Y+A SPDE ALV
Sbjct: 679 VCESPQCSSSSACCTETEKQHGDAGLLNGKAESLPGQPLACNLCYEAESPDEAALVYAAR 738
Query: 511 SVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGA 570
+ TL R + + L F +L I PF KRM ++VR + ++ Y KGA
Sbjct: 739 AYQCTLRSRTPEQVMVDFAALGPLTFQLLHILPFDSVRKRMSVVVRHPLSNQVVVYTKGA 798
Query: 571 DVVMAGIVQY---------------NDWLEEECGNMAREGLRVLVVAKKSLAEEQYQDFE 615
D V+ ++ + ++ + A++GLR L +AKK +++ +Y ++
Sbjct: 799 DSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWL 858
Query: 616 ARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWM 675
+ A+ S+ +R + LE ++ LL TG+ED+LQ V ++E L AGIK+WM
Sbjct: 859 RNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWM 918
Query: 676 LTGDKLETATCTAKNAHLV----------TRNQDIHVFRLVTNRGEAHLELNAFRRKHDC 725
LTGDK ETA A L+ T+++D + T E + A +
Sbjct: 919 LTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKKTQALPEQVSL 978
Query: 726 A-----------------LVISGDSLEVCLKY-YEYEFMELACQCPAVVCCRCAPTQKAQ 767
+ L+I+G +LE L+ + +F+EL C AVVCCR P QK++
Sbjct: 979 SEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLELTSWCQAVVCCRATPLQKSE 1038
Query: 768 IVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRL 827
+V+L++ +T A+GDG NDVSMIQ +D G+GV G+EG QA +A+DF+++QFKHL +L
Sbjct: 1039 VVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKL 1098
Query: 828 LMVHGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMF 887
L+VHG Y R + + + ++++ + + F+ + +++I ++ ++T
Sbjct: 1099 LLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSA 1158
Query: 888 -PVFSLVLDKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLF 946
PV VL+KDV +E M PELY+ K TF I +L + YQ + +
Sbjct: 1159 PPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTY 1218
Query: 947 ESEFVHIVAI------SFTSLILTELLMVALTIQTWHWLMTVAELLSLACYIASLVF 997
+ I A + ++L L++ + ++ H L+ + +LS ++ ++VF
Sbjct: 1219 QGSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSY--FLFAIVF 1273
Score = 162 bits (409), Expect = 2e-39
Identities = 123/404 (30%), Positives = 194/404 (48%), Gaps = 45/404 (11%)
Query: 47 EKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYW 106
EK Y N I KY F+P LF QF NLYFL L +VP +
Sbjct: 65 EKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITM 124
Query: 107 VPLGFVLAVTVIREAVEEIRCYVRDKEVNS---QVYSRLTARGTVKVKSSNIQVGDLIIV 163
+PL VL + I++ +E+ R Y DK++N+ +VYSR + + ++ VGD I +
Sbjct: 125 LPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWK-DVTVGDFIRL 183
Query: 164 EKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYV 223
N+ +PADM+ L +++ +G C + T LDGE++ K R V + D + S +
Sbjct: 184 SCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRI 243
Query: 224 YAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAG-TVVASGTVVGVVLYTGRELRS 282
E PN D+ F G + + LS EN L G T+ + VVG+V+Y G E ++
Sbjct: 244 ECESPNNDLSRFRGFLEHSNKE---RVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKA 300
Query: 283 VMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMV-ALQHFAGRW------------- 328
++N S PR K + N T +L+ +++V + + A+ H G W
Sbjct: 301 MLNNSGPRYKRSKLERRAN--TDVLWCVMLLVIMCLTGAVGH--GIWLSRYEKMHFFNVP 356
Query: 329 -------------YLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRD-----SKIPG 370
+ ++L +IPISL V++++ K+ + I+ D K+
Sbjct: 357 EPDGHIISPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDS 416
Query: 371 TV-VRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAY 413
V R+ I E LG+I YL +DKTGTLT+N+M+F+R + Y
Sbjct: 417 IVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDY 460
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 235 bits (599), Expect = 2e-61
Identities = 168/568 (29%), Positives = 276/568 (48%), Gaps = 58/568 (10%)
Query: 470 TPVYESNGVTDQAE------AEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSS 523
T SNG + QA+ A++Q + Y+A SPDE ALV + LV R
Sbjct: 662 TSAIASNGYSSQADNWASELAQEQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQ 721
Query: 524 MQLRTPGDQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQ---- 579
+ + P L F +L F KRM +++R T EI Y KGAD V+ ++Q
Sbjct: 722 VSVELPHLGRLTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSS 781
Query: 580 ------YNDWLEEECGNM----AREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRS 629
+ + + N A EGLR L +AK+ L++E+Y + +++A+ S+ +
Sbjct: 782 VDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSE 841
Query: 630 LKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAK 689
+ LE + LL TG+ED+LQ V T+ LR AG+++W+LTGDK ETA A
Sbjct: 842 ELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAY 901
Query: 690 NAHLVTRNQDIHVFRLVTNRGEA--------HLELNAFRRKHD-------------C--- 725
L+ ++++ + A +++ +R + C
Sbjct: 902 ACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPS 961
Query: 726 ---------ALVISGDSLEVCL-KYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQER 775
+LVI G SL L K E +F+ LA QC +V+CCR P QK+ +V+L++ +
Sbjct: 962 TSTASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSK 1021
Query: 776 TGKLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNS 835
+T A+GDG NDVSMIQ +D GVG+ G+EG QA +A+DF++ +F++L RLL++HG
Sbjct: 1022 LKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWC 1081
Query: 836 YKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMF-PVFSLVL 894
Y R A + + +++ + F F++ + + +I ++ +++ P+ + VL
Sbjct: 1082 YSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVL 1141
Query: 895 DKDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIV 954
D+DV + V + P+LYK +TF + + +Q L + V +
Sbjct: 1142 DRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLF 1201
Query: 955 AIS---FTSLILTELLMVALTIQTWHWL 979
T +LT LL + + +TW WL
Sbjct: 1202 TWGTPIVTIALLTFLLHLGIETKTWTWL 1229
Score = 159 bits (402), Expect = 1e-38
Identities = 118/403 (29%), Positives = 192/403 (47%), Gaps = 42/403 (10%)
Query: 51 QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLG 110
Q N + KY +FLP LF QF N+YF+ +A FVP + P+
Sbjct: 57 QHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVL 116
Query: 111 FVLAVTVIREAVEEIRCYVRDKEVNSQ---VYSRLTARGTVKVKSSNIQVGDLIIVEKNQ 167
F+LA+T R+ E+ + D ++N V+SR + V I VGD + + N+
Sbjct: 117 FILAITAFRDLWEDYSRHRSDHKINHLGCLVFSR-EEKKYVNRFWKEIHVGDFVRLRCNE 175
Query: 168 RVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEE 227
PAD++ L +S+ +G C + T LDGET+ K R V L + + L S + E+
Sbjct: 176 IFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEK 235
Query: 228 PNIDIHNFVGTFTREDSDPPISESLSIENTLWAG-TVVASGTVVGVVLYTGRELRSVMNT 286
PN D+ F G ++ L EN L G T+ + VVG+V+Y G E ++++N
Sbjct: 236 PNNDLSRFRGCIIHDNGK---KAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNN 292
Query: 287 SNPRSKIGLFDLEVNCLTKILFGALVVVSL-VMVALQHFAGRWYLQ-------------- 331
S PR K + ++NC +L+ L++V + + A+ H W Q
Sbjct: 293 SGPRYKRSKLERQMNC--DVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGS 350
Query: 332 -----------IIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI------PGTVVR 374
+ +++ +IPISL V++++ K + I +D ++ R
Sbjct: 351 SLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCR 410
Query: 375 SSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDS 417
+ I E LG+I Y+ +DKTGTLT+N+M+F+R + V Y D+
Sbjct: 411 ALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDA 453
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 143 bits (361), Expect = 7e-34
Identities = 99/342 (28%), Positives = 170/342 (49%), Gaps = 32/342 (9%)
Query: 52 RYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGF 111
+Y N I KYN TFLP LF QF+ N YFL L Q +P++ + +T VPL
Sbjct: 28 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
Query: 112 VLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKS-SNIQVGDLIIVEKNQRVP 170
VL +T +++A ++ + D +VN++ S++ G ++ + N+ VGD+I +E NQ V
Sbjct: 88 VLTITAVKDATDDYFRHKSDNQVNNR-QSQVLINGILQQEQWMNVCVGDIIKLENNQFVA 146
Query: 171 ADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNI 230
AD++ L +SE +G C++ T +LDGET+ K+R + T L + L + V E PN
Sbjct: 147 ADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNN 206
Query: 231 DIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGT-VVGVVLYTGRELRSVMNTSNP 289
+ F GT +++ P+S +N L G V+ + G+V++ G + + + N+
Sbjct: 207 KLDKFSGTLYWKENKFPLSN----QNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262
Query: 290 RSKIGLFDLEVNCLTKILFGALVVVSLVM----VALQHFAGR-------W---------- 328
+ K D +N L +FG LV + +++ +H G W
Sbjct: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS 322
Query: 329 -YLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIP 369
+L ++++ + ++PISL V +W + R+S P
Sbjct: 323 GFLSFWSYIIILNTVVPISLYVRYVPS---LTWGLSRESGGP 361
>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
Length = 1035
Score = 89.7 bits (221), Expect = 1e-17
Identities = 182/834 (21%), Positives = 311/834 (37%), Gaps = 178/834 (21%)
Query: 149 KVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQ 208
++ + + VGDL+ ++ RVPAD+ L C + L GE++ + R P CT
Sbjct: 190 QINADQLVVGDLVEMKGGDRVPADIRILAAQ----GCKVDNSSLTGESEPQTRSP-ECTH 244
Query: 209 RLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGT 268
P L N + T+ GT
Sbjct: 245 ESP----------------------------------------LETRNIAFFSTMCLEGT 264
Query: 269 VVGVVLYTG------RELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQ 322
V G+V+ TG R N ++ I + E+ I+ G ++ +
Sbjct: 265 VQGLVVNTGDRTIIGRIASLASGVENEKTPIAI---EIEHFVDIIAGLAILFGATFFIVA 321
Query: 323 HFAGRWYLQ-IIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQ 381
G +L+ ++ F+ + +P L + + S +R + VV++ E
Sbjct: 322 MCIGYTFLRAMVFFMAIVVAYVPEGLLATVT---VCLSLTAKRLAS-KNCVVKNLEAVET 377
Query: 382 LGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKG 441
LG S + +DKTGTLTQN M L + D+ ++ F
Sbjct: 378 LGSTSVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFD-------------- 423
Query: 442 PTLTTKVRRTMSSRVHEAV-KAIALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQA--- 497
SS A+ + + LC+ A K +D+ V +
Sbjct: 424 ----------QSSETWRALCRVLTLCNRA--------------AFKSGQDAVPVPKRIVI 459
Query: 498 SSPDEVALVQWTE-SVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRMGIIVR 556
E AL++++E ++G + RD+ P + F Q+ T E R
Sbjct: 460 GDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKF---QLSIHTLEDPR------ 510
Query: 557 DESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLAEEQYQD-FE 615
MKGA + + E C + +L+ ++ +EQ+++ F+
Sbjct: 511 ---DPRHLLVMKGAP----------ERVLERCSS-------ILIKGQELPLDEQWREAFQ 550
Query: 616 ARYV-------------QAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQL---QADV 659
Y+ Q L+ D A +E++ LC G+ + +A V
Sbjct: 551 TAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATV 610
Query: 660 RPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAF 719
+ R AGI+V M+TGD TA A + +++ + + + ++
Sbjct: 611 PDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSET----VEDIAARLRVPVDQV 666
Query: 720 RRKHDCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKL 779
RK A VI+G L+ E +E P +V R +P QK IV Q R G +
Sbjct: 667 NRKDARACVINGMQLK---DMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQ-RLGAI 722
Query: 780 TCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADF--------SITQFKHLGRLLMVH 831
GDG ND ++++D GV + A AAD SI GRL+
Sbjct: 723 VAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIF-- 780
Query: 832 GRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYT-MFPVF 890
++ K+S A + + +++ T ++ +V SVPL G + I + + T +FP
Sbjct: 781 --DNLKKSIA---YTLTKNIPELTPYLIYITV----SVPLPLGCITILFIELCTDIFPSV 831
Query: 891 SLVLDKDVKSEVAMLYPELYK-DLLKGRPLSYKTFLIWVLISIYQGSTIMYGAL 943
SL +K +S++ L P K D L PL+ ++ I + G T + A+
Sbjct: 832 SLAYEK-AESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFTAM 884
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 86.3 bits (212), Expect = 1e-16
Identities = 204/957 (21%), Positives = 372/957 (38%), Gaps = 191/957 (19%)
Query: 23 GCCEWLRCCGGGEARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFN 82
G E + C E + G R Y N I + + F L + N F Y F
Sbjct: 161 GLDEGVSCTSIYEKHSAGLTKGMHAYRKLLYGVNEIAVKVPSVFKLLIKEVLNPF-YIFQ 219
Query: 83 LYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRC-YVRDKEVNSQVYSR 141
L+ ++L + Y Y+ V+++ I ++ IR YV ++ V +
Sbjct: 220 LFSVILWSTDE---------YYYYALAIVVMSIVSIVSSLYSIRKQYVM---LHDMVATH 267
Query: 142 LTARGTV--------KVKSSNIQVGDLIIVEKNQRV-PADMIFLRTSEKNGSCFLRTDQL 192
T R +V ++ S+++ GD++++ N + P D + + NG+C + L
Sbjct: 268 STVRVSVCRVNEEIEEIFSTDLVPGDVMVIPLNGTIMPCDAVLI-----NGTCIVNESML 322
Query: 193 DGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESL 252
GE+ +PV T + D+ I +Y E + F GT
Sbjct: 323 TGES-----VPVTKTNLPNPSVDVKGIGDELYNPETHKRHTLFCGTTV------------ 365
Query: 253 SIENTLWAGTVVASGTV-VGVVLYTGRELRSVMNTSNPRSKIG----LFDLEVNCLTKIL 307
I+ + G +V + V G G+ +RS++ K+ LF L CL +
Sbjct: 366 -IQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLL---CLVAVA 421
Query: 308 FGALVVVSLVMVALQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSK 367
+ + + + G + II L + + +P +L + G IVY+ RR K
Sbjct: 422 GIGFIYTIINSILNEVQVG---VIIIESLDIITITVPPALPAAMTAG-IVYAQ--RRLKK 475
Query: 368 IPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFS 427
I G S G+++ + DKTGTLT++ G +G+ ++ +
Sbjct: 476 I-GIFCISPQRINICGQLNLVCFDKTGTLTED---------GLDLWGIQRVENARF---- 521
Query: 428 IYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAE-K 486
P + K + V +A CH++T + GV + K
Sbjct: 522 ------LSPEENVCNEMLVK---------SQFVACMATCHSLTKI---EGVLSGDPLDLK 563
Query: 487 QYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTP-GDQILNFT-------- 537
+E + + ++ +E AL + T+V + + TP G+Q +
Sbjct: 564 MFEAIGWILEEATEEETAL---HNRIMPTVVRPPKQLLPESTPAGNQEMELFELPATYEI 620
Query: 538 -ILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGI-------VQYNDWLEEECG 589
I++ FPF+ +RM ++ R ++ YMKGA +AG+ V + + LE+
Sbjct: 621 GIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPVDFQNVLED--- 677
Query: 590 NMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVI-ESLEMEMELLCL 648
++G RV+ +A + L ++KL+ H KV + +++E M+ + L
Sbjct: 678 -FTKQGFRVIALAHRKL-------------ESKLTWH----KVQNISRDAIENNMDFMGL 719
Query: 649 TGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTN 708
++++L+ + LE L A I+ M+TGD + TA A++ ++ + + +
Sbjct: 720 IIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVIIAEALPP 779
Query: 709 RGEAHLELN---------------------AFRRKHDCA---------LVISGDSLEVCL 738
+ ++N + HD ++G S V L
Sbjct: 780 KDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVIL 839
Query: 739 KYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDC 798
++++ +L V R AP QK Q++ LQ GDG ND ++ +
Sbjct: 840 EHFQDLVPKLMLH--GTVFARMAPDQKTQLIEALQ-NVDYFVGMCGDGANDCGALKRAHG 896
Query: 799 GVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCISTMQA 858
G+ + E AS+A+ F+ + V R+A ++ F C+ A
Sbjct: 897 GISLSELE---ASVASPFT----SKTPSISCVPNLIREGRAALITSF------CVFKFMA 943
Query: 859 VFSSVFYFASVPLYQ--------GFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYP 907
++S + YF+ LY FL I + I + VF++ L+ K VA P
Sbjct: 944 LYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVV--VFTMSLNPAWKELVAQRPP 998
>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
Length = 1020
Score = 84.7 bits (208), Expect = 4e-16
Identities = 190/858 (22%), Positives = 328/858 (38%), Gaps = 182/858 (21%)
Query: 148 VKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACT 207
+++ + + VGDL+ V+ RVPAD LR +G C + L GE++ + R P
Sbjct: 176 MQINAEEVVVGDLVEVKGGDRVPAD---LRIISSHG-CKVDNSSLTGESEPQTRSP---- 227
Query: 208 QRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASG 267
FT E+ L N + T G
Sbjct: 228 ------------------------------EFTHENP-------LETRNICFFSTNCVEG 250
Query: 268 TVVGVVLYTG-RELRSVMNTSNPRSKIGL--FDLEVNCLTKILFGALVVVSLVMVALQHF 324
T G+V+ TG R + + T ++G +E+ +++ G V + + L
Sbjct: 251 TARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLI 310
Query: 325 AGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGR 384
G +L+ + FL+ II ++ L V + + +V++ E LG
Sbjct: 311 LGYSWLEAVIFLI---GIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGS 367
Query: 385 ISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTL 444
S + +DKTGTLTQN M + + D+ ++ F ++ PT
Sbjct: 368 TSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFD-----------KRSPTW 416
Query: 445 TTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVA 504
T R LC+ V+++ Q D+ A E A
Sbjct: 417 TALSR------------IAGLCNRA--VFKAG----QENISVSKRDT-----AGDASESA 453
Query: 505 LVQWTE-SVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESK-RMGIIVRDESTGE 562
L++ E S G RD+ N + +I PF +K ++ I R++S
Sbjct: 454 LLKCIELSCGSVRKMRDR-------------NPKVAEI-PFNSTNKYQLSIHEREDSPQS 499
Query: 563 ITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLAEEQYQD-FEARYVQ- 620
MKGA + + + C +LV K+ +++ QD F+ Y++
Sbjct: 500 HVLVMKGAP----------ERILDRCST-------ILVQGKEIPLDKEMQDAFQNAYMEL 542
Query: 621 ----------AKLSVHD----RSLKVATVIESLEMEMELLCLTGVEDQL---QADVRPTL 663
+L++ R K T + L E LC G+ + +A V +
Sbjct: 543 GGLGERVLGFCQLNLPSGKFPRGFKFDT--DELNFPTEKLCFVGLMSMIDPPRAAVPDAV 600
Query: 664 ETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKH 723
R+AGIKV M+TGD TA AK +++ + + ++ ++ +
Sbjct: 601 GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE----TVEDIAARLNIPMSQVNPRE 656
Query: 724 DCALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAV 783
A V+ G L+ + E+ +V R +P QK IV Q R G +
Sbjct: 657 AKACVVHGSDLK---DMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQ-RQGAIVAVT 712
Query: 784 GDGGNDVSMIQESDCGV--GVEGKE-GKQAS----LAADF-SITQFKHLGRLLMVHGRNS 835
GDG ND ++++D G+ G+ G + KQA+ L +F SI GRL+ ++
Sbjct: 713 GDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIF----DN 768
Query: 836 YKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLD 895
K+S A +L + + +F A++PL G + I + L
Sbjct: 769 LKKSIAY-------TLTSNIPEITPFLLFIIANIPLPLGTVTI-----------LCIDLG 810
Query: 896 KDVKSEVAMLYPELYKDLLKGRPLSYKT--FLIWVLISIYQGSTIMYGALLLFESEFVHI 953
D+ +++ Y D++K +P + +T + LIS+ G M AL F F +
Sbjct: 811 TDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGF---FTYF 867
Query: 954 VAISFTSLILTELLMVAL 971
V ++ + + LL + L
Sbjct: 868 VILAENGFLPSRLLGIRL 885
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
Length = 1029
Score = 81.6 bits (200), Expect = 3e-15
Identities = 180/858 (20%), Positives = 312/858 (36%), Gaps = 174/858 (20%)
Query: 148 VKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACT 207
+++ + +GDL+ ++ RVPAD+ + C + L GE++ + R P
Sbjct: 186 MQINVQEVVLGDLVEIKGGDRVPADLRLISAQ----GCKVDNSSLTGESEPQSRSP---- 237
Query: 208 QRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASG 267
FT E+ L N + T G
Sbjct: 238 ------------------------------DFTHENP-------LETRNICFFSTNCVEG 260
Query: 268 TVVGVVLYTGREL---RSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQHF 324
T G+V+ TG R TS E+ ++ V + + AL
Sbjct: 261 TARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLL 320
Query: 325 AGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGR 384
G +L+ I FL+ II ++ L V + + +V++ E LG
Sbjct: 321 LGYGWLEAIIFLI---GIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGS 377
Query: 385 ISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTL 444
S + +DKTGTLTQN M + Y D+ +E Q G T
Sbjct: 378 TSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEE------------------QTGKTF 419
Query: 445 TTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVA 504
T SS + IA G+ ++A+ + E +A++ D
Sbjct: 420 TK------SSDTWFMLARIA------------GLCNRADFKANQEILPIAKRATTGDA-- 459
Query: 505 LVQWTESVGLTLVGRDQSSM-QLRTPGDQILNFTILQIFPFTYESK-RMGIIVRDESTGE 562
+ES L + + SS+ ++R ++ PF +K +M I +R++S+
Sbjct: 460 ----SESALLKFIEQSYSSVAEMREKNPKVAEI------PFNSTNKYQMSIHLREDSSQT 509
Query: 563 ITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAK 622
MKGA + + E C G + S+ +E + F+ Y++
Sbjct: 510 HVLMMKGAP----------ERILEFCSTFLLNG------QEYSMNDEMKEAFQNAYLELG 553
Query: 623 LSVHDRSLKVATV-------------IESLEMEMELLCLTGVEDQL---QADVRPTLETL 666
+ +R L + + + M+ LC G+ + +A V +
Sbjct: 554 -GLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKC 612
Query: 667 RNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDC- 725
R+AGIKV M+TGD TA AK +++ + E L K D
Sbjct: 613 RSAGIKVIMVTGDHPITAKAIAKGVGIISEGTE--------TAEEVAARLKIPISKVDAS 664
Query: 726 ---ALVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCA 782
A+V+ G L+ + ++ P +V R +P QK IV Q R G +
Sbjct: 665 AAKAIVVHGAELK---DIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGCQ-RLGAVVAV 720
Query: 783 VGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAAL 842
GDG ND ++++D G+ + G G S K ++++ + +
Sbjct: 721 TGDGVNDSPALKKADIGIAM-GISGSDVS----------KQAADMILLDDNFASIVTGVE 769
Query: 843 SQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEV 902
+I +L S M + S++ + + F+I+G + + L D+ +
Sbjct: 770 EGRLIFDNLKKSIMYTLTSNI---PEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAI 826
Query: 903 AMLYPELYKDLLKGRPLSYKT--FLIWVLISIYQGSTIMYGALLLFESEFVHIVAISFTS 960
++ Y D++K P + KT + LI + G M AL F + FV + F
Sbjct: 827 SLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRP 886
Query: 961 LILTELLMVALTIQTWHW 978
+ +LL + L HW
Sbjct: 887 V---DLLGIRL-----HW 896
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
[Homo sapiens]
Length = 994
Score = 72.8 bits (177), Expect = 2e-12
Identities = 165/792 (20%), Positives = 293/792 (36%), Gaps = 184/792 (23%)
Query: 72 VLFNQFKYFFNLYFLLLACSQFV------PEMRLGALYTYWVPLGFVLAVTVI-----RE 120
++ QF+ LL AC FV E + A +V L ++A ++ R
Sbjct: 52 LVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERN 111
Query: 121 AVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSE 180
A I + +VY R + ++K+ +I GD++ V +VPAD+ L
Sbjct: 112 AENAIEALKEYEPEMGKVY-RADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIK- 169
Query: 181 KNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT 240
S LR DQ S + E ++ H
Sbjct: 170 ---STTLRVDQ-----------------------------SILTGESVSVIKHT------ 191
Query: 241 REDSDPPISESLSIENTLWAGTVVASGTVVGVVLYTG-----RELRSVMNTSNP-----R 290
E P + + +N L++GT +A+G +G+V TG ++R M + +
Sbjct: 192 -EPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQ 250
Query: 291 SKIGLFDLEVNCLTKILFGALVVVSLVMVALQHF-----AGRWYLQIIRFLLLFSNIIPI 345
K+ F + L+K++ +L+ V++ ++ + HF G W+ I + + +
Sbjct: 251 QKLDEFGEQ---LSKVI--SLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVA 305
Query: 346 SLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKR 405
++ L + R +VRS E LG S + +DKTGTLT N+M +
Sbjct: 306 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCK 365
Query: 406 LHLGTVAYGLDSMDEVQSHI-----FSIYTQQSQDPPAQKGPTLTT--KVRRTMSSRVHE 458
+ + +D+V I FSI + A +G L VR + E
Sbjct: 366 MFI---------IDKVDGDICLLNEFSI----TGSTYAPEGEVLKNDKPVRPGQYDGLVE 412
Query: 459 AVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVG 518
ALC++ + D EA+ YE + E AL E + +
Sbjct: 413 LATICALCNDSS--------LDFNEAKGVYE------KVGEATETALTTLVEKMNVFNTD 458
Query: 519 -RDQSSMQLRTPGDQILNFTILQIF--PFTYESKRMGIIVRDESTGEIT----FYMKGAD 571
R S ++ + ++ + + F F+ + K M + + ++KGA
Sbjct: 459 VRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAP 518
Query: 572 ----------------VVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSL---AEEQYQ 612
V + G V+ + R+ LR L +A + EE
Sbjct: 519 EGVIDRCNYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVL 578
Query: 613 DFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIK 672
D AR+++ E ++ + + G+ D + +V +++ R+AGI+
Sbjct: 579 DDSARFLE------------------YETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIR 620
Query: 673 VWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGD 732
V M+TGD TA + + N+++ R T R L L +
Sbjct: 621 VIMITGDNKGTAIAICRRIGIFGENEEV-ADRAYTGREFDDLPL--------------AE 665
Query: 733 SLEVCLKYYEYEFMELACQCPAVVCC--RCAPTQKAQIVRLLQERTGKLTCAVGDGGNDV 790
E C + CC R P+ K++IV LQ ++T GDG ND
Sbjct: 666 QREACRR----------------ACCFARVEPSHKSKIVEYLQS-YDEITAMTGDGVNDA 708
Query: 791 SMIQESDCGVGV 802
+++++ G+ +
Sbjct: 709 PALKKAEIGIAM 720
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
[Homo sapiens]
Length = 1001
Score = 72.8 bits (177), Expect = 2e-12
Identities = 165/792 (20%), Positives = 293/792 (36%), Gaps = 184/792 (23%)
Query: 72 VLFNQFKYFFNLYFLLLACSQFV------PEMRLGALYTYWVPLGFVLAVTVI-----RE 120
++ QF+ LL AC FV E + A +V L ++A ++ R
Sbjct: 52 LVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERN 111
Query: 121 AVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSE 180
A I + +VY R + ++K+ +I GD++ V +VPAD+ L
Sbjct: 112 AENAIEALKEYEPEMGKVY-RADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIK- 169
Query: 181 KNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT 240
S LR DQ S + E ++ H
Sbjct: 170 ---STTLRVDQ-----------------------------SILTGESVSVIKHT------ 191
Query: 241 REDSDPPISESLSIENTLWAGTVVASGTVVGVVLYTG-----RELRSVMNTSNP-----R 290
E P + + +N L++GT +A+G +G+V TG ++R M + +
Sbjct: 192 -EPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQ 250
Query: 291 SKIGLFDLEVNCLTKILFGALVVVSLVMVALQHF-----AGRWYLQIIRFLLLFSNIIPI 345
K+ F + L+K++ +L+ V++ ++ + HF G W+ I + + +
Sbjct: 251 QKLDEFGEQ---LSKVI--SLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVA 305
Query: 346 SLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKR 405
++ L + R +VRS E LG S + +DKTGTLT N+M +
Sbjct: 306 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCK 365
Query: 406 LHLGTVAYGLDSMDEVQSHI-----FSIYTQQSQDPPAQKGPTLTT--KVRRTMSSRVHE 458
+ + +D+V I FSI + A +G L VR + E
Sbjct: 366 MFI---------IDKVDGDICLLNEFSI----TGSTYAPEGEVLKNDKPVRPGQYDGLVE 412
Query: 459 AVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVG 518
ALC++ + D EA+ YE + E AL E + +
Sbjct: 413 LATICALCNDSS--------LDFNEAKGVYE------KVGEATETALTTLVEKMNVFNTD 458
Query: 519 -RDQSSMQLRTPGDQILNFTILQIF--PFTYESKRMGIIVRDESTGEIT----FYMKGAD 571
R S ++ + ++ + + F F+ + K M + + ++KGA
Sbjct: 459 VRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAP 518
Query: 572 ----------------VVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSL---AEEQYQ 612
V + G V+ + R+ LR L +A + EE
Sbjct: 519 EGVIDRCNYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVL 578
Query: 613 DFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIK 672
D AR+++ E ++ + + G+ D + +V +++ R+AGI+
Sbjct: 579 DDSARFLE------------------YETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIR 620
Query: 673 VWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGD 732
V M+TGD TA + + N+++ R T R L L +
Sbjct: 621 VIMITGDNKGTAIAICRRIGIFGENEEV-ADRAYTGREFDDLPL--------------AE 665
Query: 733 SLEVCLKYYEYEFMELACQCPAVVCC--RCAPTQKAQIVRLLQERTGKLTCAVGDGGNDV 790
E C + CC R P+ K++IV LQ ++T GDG ND
Sbjct: 666 QREACRR----------------ACCFARVEPSHKSKIVEYLQS-YDEITAMTGDGVNDA 708
Query: 791 SMIQESDCGVGV 802
+++++ G+ +
Sbjct: 709 PALKKAEIGIAM 720
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 70.1 bits (170), Expect = 1e-11
Identities = 201/953 (21%), Positives = 363/953 (38%), Gaps = 168/953 (17%)
Query: 56 NVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAV 115
N I+ + + L + N F Y F L+ + L S+ E + + + L V
Sbjct: 185 NTIDVEVTPIWKLLIKEVLNPF-YIFQLFSVCLWFSEDYKEYAFAIIIMSIISIS--LTV 241
Query: 116 TVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQV-GDLIIVEKNQ-RVPADM 173
+RE + ++ + + NS S + V+ S + V GDL+I+ N+ +P D
Sbjct: 242 YDLRE--QSVKLHHLVESHNSITVSVCGRKAGVQELESRVLVPGDLLILTGNKVLMPCDA 299
Query: 174 IFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIH 233
+ + GSC + L GE+ +PV T P +D
Sbjct: 300 VLIE-----GSCVVDEGMLTGES-----IPVTKTPL------------------PKMD-- 329
Query: 234 NFVGTFTREDSDPPISESLSIENTLWAGTVV------ASGTVVGVVLYTG-RELRSVMNT 286
+ V T+ ++D + L+ GT V SGTV VVL TG + +
Sbjct: 330 SSVPWKTQSEADYK-------RHVLFCGTEVIQAKAACSGTVRAVVLQTGFNTAKGDLVR 382
Query: 287 SNPRSKIGLFDLEVNCLTKIL--FGALVVVSLVMVALQHFAGRWYLQIIRFLL-LFSNII 343
S K F L + + +L G + + + + +G +++R L + + +
Sbjct: 383 SILYPKPVNFQLYRDAIRFLLCLVGTATIGMIYTLCVYVLSGEPPEEVVRKALDVITIAV 442
Query: 344 PISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIF 403
P +L L G I+Y+ +R K G S G+++ + DKTGTLT++ +
Sbjct: 443 PPALPAALTTG-IIYA---QRRLKKRGIFCISPQRINVCGQLNLVCFDKTGTLTRDGLDL 498
Query: 404 KRLHLGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAI 463
G V+ + EV S + GP A+
Sbjct: 499 ----WGVVSCDRNGFQEVHSF--------ASGQALPWGPLCA----------------AM 530
Query: 464 ALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSS 523
A CH++ + +G + + ++ A S D+ + + R S
Sbjct: 531 ASCHSLILL---DGTIQGDPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMVVKPCRTASQ 587
Query: 524 MQLRTPGDQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYNDW 583
+ + IL FPF+ +RM +IV+ E G+ +MKGA +A Q
Sbjct: 588 VPVE-------GIAILHQFPFSSALQRMTVIVQ-EMGGDRLAFMKGAPERVASFCQPETV 639
Query: 584 ---LEEECGNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLE 640
E +G RV+ +A K L + + R E++E
Sbjct: 640 PTSFVSELQIYTTQGFRVIALAYKKLENDHHATTLTR-------------------ETVE 680
Query: 641 MEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDI 700
++ L L +E++L+ + +P LE L +A I+ M+TGD L+TA A+ + +V+ +Q +
Sbjct: 681 SDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKV 740
Query: 701 HVFRLVTNRGEA-------------HL-------------ELNAFRRKHDCALVISGDSL 734
+ G + H+ E++ R+ ++G S
Sbjct: 741 ILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSF 800
Query: 735 EVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQ 794
V +++ ++ + R +P QK+ +V Q + GDG ND ++
Sbjct: 801 HVISQHFSSLLPKILIN--GTIFARMSPGQKSSLVEEFQ-KLDYFVGMCGDGANDCGALK 857
Query: 795 ESDCGVGVEGKEGKQASLAADF-SITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCI 853
+ G+ + +E AS+A+ F S T L+ GR AAL S C+
Sbjct: 858 MAHVGISLSEQE---ASVASPFTSKTPNIECVPHLIKEGR------AALV-----TSFCM 903
Query: 854 STMQAVFSSVFYFASVPLY-QGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPELYKD 912
A++S + Y + LY + + Y ++ + +L+ V + YP+L
Sbjct: 904 FKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLI---GVTMNLNGAYPKLVPF 960
Query: 913 LLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIVAISFTSLILTE 965
GR +S L+ V+ +I + +L + + + V I + E
Sbjct: 961 RPAGRLIS-PPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNE 1012
>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
Length = 1175
Score = 69.3 bits (168), Expect = 2e-11
Identities = 128/568 (22%), Positives = 221/568 (38%), Gaps = 116/568 (20%)
Query: 383 GRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGP 442
G++ + DKTGTLT++ GLD M V KG
Sbjct: 500 GKLQLVCFDKTGTLTED--------------GLDVMGVVPL----------------KGQ 529
Query: 443 TLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQASSPDE 502
V V ++A+A CH ++ + ++ V D + K E + V + +E
Sbjct: 530 AFLPLVPEPRRLPVGPLLRALATCHALSRLQDTP-VGDPMDL-KMVESTGWVLE----EE 583
Query: 503 VALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRMGIIVRDESTGE 562
A + L ++ QL+ + + ++L FPF+ +RM ++V +
Sbjct: 584 PAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQ 643
Query: 563 ITFYMKGADVVMAGIVQYNDWLEEECGNMARE----GLRVLVVAKKSLAEEQYQDFEARY 618
Y+KG+ ++AG+ + + + M + G RV+ +A K L
Sbjct: 644 PEAYVKGSPELVAGLCN-PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVP-------- 694
Query: 619 VQAKLSVHDRSLKVATVI--ESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWML 676
SL+ A + +++E ++ LL L + + L+ P ++ LR I+ M+
Sbjct: 695 ----------SLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMV 744
Query: 677 TGDKLETATCTAKNAHLVTRNQDIHVFRLV-TNRGE-AHLE---------LNAFRRKHDC 725
TGD L+TA A+ +V + + + RG+ A LE +N +
Sbjct: 745 TGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQA 804
Query: 726 A------------LVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQ 773
A L +SG + + +K++ ++ Q V R AP QK ++V LQ
Sbjct: 805 ASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQ--GTVFARMAPEQKTELVCELQ 862
Query: 774 ERTGKLTCAV---GDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMV 830
KL V GDG ND ++ +D G+ + E AS+ + F+
Sbjct: 863 ----KLQYCVGMCGDGANDCGALKAADVGISLSQAE---ASVVSPFT------------- 902
Query: 831 HGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYT-MFPV 889
S S VI C ++ FS Y A L Q ++ TI T + +
Sbjct: 903 ----SSMASIECVPMVIREGRC--SLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDL 956
Query: 890 FSLVLDKDVKSEVAMLYPELYKDLLKGR 917
L +D + + VA+L L+ GR
Sbjct: 957 QFLAIDLVITTTVAVLMSRTGPALVLGR 984
>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
Length = 1180
Score = 69.3 bits (168), Expect = 2e-11
Identities = 128/568 (22%), Positives = 221/568 (38%), Gaps = 116/568 (20%)
Query: 383 GRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGP 442
G++ + DKTGTLT++ GLD M V KG
Sbjct: 505 GKLQLVCFDKTGTLTED--------------GLDVMGVVPL----------------KGQ 534
Query: 443 TLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSCRVYQASSPDE 502
V V ++A+A CH ++ + ++ V D + K E + V + +E
Sbjct: 535 AFLPLVPEPRRLPVGPLLRALATCHALSRLQDTP-VGDPMDL-KMVESTGWVLE----EE 588
Query: 503 VALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRMGIIVRDESTGE 562
A + L ++ QL+ + + ++L FPF+ +RM ++V +
Sbjct: 589 PAADSAFGTQVLAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQRMSVVVAWPGATQ 648
Query: 563 ITFYMKGADVVMAGIVQYNDWLEEECGNMARE----GLRVLVVAKKSLAEEQYQDFEARY 618
Y+KG+ ++AG+ + + + M + G RV+ +A K L
Sbjct: 649 PEAYVKGSPELVAGLCN-PETVPTDFAQMLQSYTAAGYRVVALASKPLPTVP-------- 699
Query: 619 VQAKLSVHDRSLKVATVI--ESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWML 676
SL+ A + +++E ++ LL L + + L+ P ++ LR I+ M+
Sbjct: 700 ----------SLEAAQQLTRDTVEGDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMV 749
Query: 677 TGDKLETATCTAKNAHLVTRNQDIHVFRLV-TNRGE-AHLE---------LNAFRRKHDC 725
TGD L+TA A+ +V + + + RG+ A LE +N +
Sbjct: 750 TGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTAVNGVKDPDQA 809
Query: 726 A------------LVISGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQ 773
A L +SG + + +K++ ++ Q V R AP QK ++V LQ
Sbjct: 810 ASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQ--GTVFARMAPEQKTELVCELQ 867
Query: 774 ERTGKLTCAV---GDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMV 830
KL V GDG ND ++ +D G+ + E AS+ + F+
Sbjct: 868 ----KLQYCVGMCGDGANDCGALKAADVGISLSQAE---ASVVSPFT------------- 907
Query: 831 HGRNSYKRSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYT-MFPV 889
S S VI C ++ FS Y A L Q ++ TI T + +
Sbjct: 908 ----SSMASIECVPMVIREGRC--SLDTSFSVFKYMALYSLTQFISVLILYTINTNLGDL 961
Query: 890 FSLVLDKDVKSEVAMLYPELYKDLLKGR 917
L +D + + VA+L L+ GR
Sbjct: 962 QFLAIDLVITTTVAVLMSRTGPALVLGR 989
>gi|170016077 ATPase type 13A1 [Homo sapiens]
Length = 1204
Score = 65.9 bits (159), Expect = 2e-10
Identities = 168/750 (22%), Positives = 281/750 (37%), Gaps = 170/750 (22%)
Query: 99 LGALYTYWVPLGFVLAVTVIREA---------VEEIRCYVRDKEVNSQVYSRLTARGTVK 149
L L YW F L++ V EA + EIR + +K QVY +R
Sbjct: 256 LWCLDEYWYYSVFTLSMLVAFEASLVQQQMRNMSEIR-KMGNKPHMIQVYR---SRKWRP 311
Query: 150 VKSSNIQVGDLIIVEKNQR---VPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVAC 206
+ S I GD++ + ++ + VP D++ LR G C + L GE+ +++ P+
Sbjct: 312 IASDEIVPGDIVSIGRSPQENLVPCDVLLLR-----GRCIVDEAMLTGESVPQMKEPIE- 365
Query: 207 TQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVAS 266
DL R V + + +H G PP + ++ V S
Sbjct: 366 --------DLSPDR--VLDLQADSRLHVIFGGTKVVQHIPPQKATTGLKP-------VDS 408
Query: 267 GTVVGVVLYTGRELRSVMNTSNPRSK----IGLFDLEVNCLTKILFGALVVVSLVMVALQ 322
G V V LR+ NTS + G+ + N L +F ++ L++ A+
Sbjct: 409 GCVAYV-------LRTGFNTSQGKLLRTILFGVKRVTANNLETFIF----ILFLLVFAIA 457
Query: 323 HFAGRW-----------YLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGT 371
A W Y + L+ ++++P L + L + V + +I +K+
Sbjct: 458 AAAYVWIEGTKDPSRNRYKLFLECTLILTSVVPPELPIELSLA--VNTSLIAL-AKLYMY 514
Query: 372 VVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQ 431
IP G++ DKTGTLT + ++ + + GL EV
Sbjct: 515 CTEPFRIPFA-GKVEVCCFDKTGTLTSDSLVVRGVA------GLRDGKEVTP-------- 559
Query: 432 QSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDS 491
+SS E +A+A CH++ + + V D E
Sbjct: 560 --------------------VSSIPVETHRALASCHSLMQLDDGTLVGDPLEKAM----- 594
Query: 492 CRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRM 551
+ V WT + + R + L+ I Q F F KRM
Sbjct: 595 -----------LTAVDWTLTKDEKVFPRSIKTQGLK----------IHQRFHFASALKRM 633
Query: 552 GIIVRDESTGEITFY----MKGADVVMAGIV-QYNDWLEEECGNMAREGLRVLVVAKKSL 606
++ E G +KGA + + Q ++REG RVL + K L
Sbjct: 634 SVLASYEKLGSTDLCYIAAVKGAPETLHSMFSQCPPDYHHIHTEISREGARVLALGYKEL 693
Query: 607 AEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETL 666
+Q +AR V+ E+LE ++ + V L+AD + + +
Sbjct: 694 GHLTHQ--QAREVKR---------------EALECSLKFVGFIVVSCPLKADSKAVIREI 736
Query: 667 RNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRG--------EAHLELNA 718
+NA +V M+TGD TA A+ H + + + + + + +G + + L
Sbjct: 737 QNASHRVVMITGDNPLTACHVAQELHFIEKAHTL-ILQPPSEKGRQCEWRSIDGSIVLPL 795
Query: 719 FRRKH-----DCALVISGDSLEVCLKYYEYEFMELACQCPAV-VCCRCAPTQKAQIVRLL 772
R + AL ++GD L + + L P V V R AP QK ++ L
Sbjct: 796 ARGSPKALALEYALCLTGDGLAHLQATDPQQLLRL---IPHVQVFARVAPKQKEFVITSL 852
Query: 773 QERTGKLTCAVGDGGNDVSMIQESDCGVGV 802
+E G +T GDG NDV ++ +D GV +
Sbjct: 853 KE-LGYVTLMCGDGTNDVGALKHADVGVAL 881
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 64.7 bits (156), Expect = 4e-10
Identities = 159/775 (20%), Positives = 288/775 (37%), Gaps = 151/775 (19%)
Query: 72 VLFNQFKYFFNLYFLLLACSQFV------PEMRLGALYTYWVPLGFVLAVTVI-----RE 120
++ QF+ LL AC FV E + A +V L ++A ++ R
Sbjct: 52 LVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERN 111
Query: 121 AVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSE 180
A I + +VY R + ++K+ +I GD++ + +VPAD+ TS
Sbjct: 112 AENAIEALKEYEPEMGKVY-RQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRL--TSI 168
Query: 181 KNGSCFLRTDQ--LDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGT 238
K S LR DQ L GE+ V
Sbjct: 169 K--STTLRVDQSILTGES---------------------------------------VSV 187
Query: 239 FTREDSDP-PISESLSIENTLWAGTVVASGTVVGVVLYTGRELR------SVMNTSNPRS 291
D P P + + +N L++GT +A+G +GVV+ TG ++ T R+
Sbjct: 188 IKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERT 247
Query: 292 KIGL-FDLEVNCLTKILFGALVVVSLVMVALQHF-----AGRWYLQIIRFLLLFSNIIPI 345
+ D L+K++ +L+ +++ ++ + HF G W I + + +
Sbjct: 248 PLQQKLDEFGEQLSKVI--SLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 305
Query: 346 SLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKR 405
++ L + R +VRS E LG S + +DKTGTLT N+M R
Sbjct: 306 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 365
Query: 406 LHLGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIAL 465
+ + LD ++ + S P + V + E AL
Sbjct: 366 MFI------LDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICAL 419
Query: 466 CHNVTPVY-ESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSM 524
C++ Y E+ GV ++ + +C V + + D TE GL+ + R +
Sbjct: 420 CNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFD-------TELKGLSKIERANAC- 471
Query: 525 QLRTPGDQILNFTILQIFPFTYESKRMGIIV-----RDESTGEITFYMKGADVVMAGIVQ 579
+ ++ + + F + R + V + T ++KGA G++
Sbjct: 472 ------NSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAP---EGVI- 521
Query: 580 YNDWLEEECGNMAREGLRVLVVAK-----KSLAEEQYQDFEARYVQAKLSVHDRSLKVAT 634
+ C ++ +V + + S+ E + A L+ HD L+
Sbjct: 522 ------DRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLA-LATHDNPLRREE 574
Query: 635 V-------IESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCT 687
+ E + + G+ D + +V +++ R AGI+V M+TGD TA
Sbjct: 575 MHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAI 634
Query: 688 AKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFME 747
+ + +++D+ G ELN ++ C
Sbjct: 635 CRRIGIFGQDEDVTSKAFT---GREFDELNPSAQRDAC---------------------- 669
Query: 748 LACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGV 802
L +C A R P+ K++IV LQ ++T GDG ND +++++ G+ +
Sbjct: 670 LNARCFA----RVEPSHKSKIVEFLQS-FDEITAMTGDGVNDAPALKKAEIGIAM 719
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
[Homo sapiens]
Length = 1042
Score = 64.7 bits (156), Expect = 4e-10
Identities = 159/775 (20%), Positives = 288/775 (37%), Gaps = 151/775 (19%)
Query: 72 VLFNQFKYFFNLYFLLLACSQFV------PEMRLGALYTYWVPLGFVLAVTVI-----RE 120
++ QF+ LL AC FV E + A +V L ++A ++ R
Sbjct: 52 LVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERN 111
Query: 121 AVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSE 180
A I + +VY R + ++K+ +I GD++ + +VPAD+ TS
Sbjct: 112 AENAIEALKEYEPEMGKVY-RQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRL--TSI 168
Query: 181 KNGSCFLRTDQ--LDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGT 238
K S LR DQ L GE+ V
Sbjct: 169 K--STTLRVDQSILTGES---------------------------------------VSV 187
Query: 239 FTREDSDP-PISESLSIENTLWAGTVVASGTVVGVVLYTGRELR------SVMNTSNPRS 291
D P P + + +N L++GT +A+G +GVV+ TG ++ T R+
Sbjct: 188 IKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERT 247
Query: 292 KIGL-FDLEVNCLTKILFGALVVVSLVMVALQHF-----AGRWYLQIIRFLLLFSNIIPI 345
+ D L+K++ +L+ +++ ++ + HF G W I + + +
Sbjct: 248 PLQQKLDEFGEQLSKVI--SLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 305
Query: 346 SLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKR 405
++ L + R +VRS E LG S + +DKTGTLT N+M R
Sbjct: 306 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 365
Query: 406 LHLGTVAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIAL 465
+ + LD ++ + S P + V + E AL
Sbjct: 366 MFI------LDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICAL 419
Query: 466 CHNVTPVY-ESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSM 524
C++ Y E+ GV ++ + +C V + + D TE GL+ + R +
Sbjct: 420 CNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFD-------TELKGLSKIERANAC- 471
Query: 525 QLRTPGDQILNFTILQIFPFTYESKRMGIIV-----RDESTGEITFYMKGADVVMAGIVQ 579
+ ++ + + F + R + V + T ++KGA G++
Sbjct: 472 ------NSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAP---EGVI- 521
Query: 580 YNDWLEEECGNMAREGLRVLVVAK-----KSLAEEQYQDFEARYVQAKLSVHDRSLKVAT 634
+ C ++ +V + + S+ E + A L+ HD L+
Sbjct: 522 ------DRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLA-LATHDNPLRREE 574
Query: 635 V-------IESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCT 687
+ E + + G+ D + +V +++ R AGI+V M+TGD TA
Sbjct: 575 MHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAI 634
Query: 688 AKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEYEFME 747
+ + +++D+ G ELN ++ C
Sbjct: 635 CRRIGIFGQDEDVTSKAFT---GREFDELNPSAQRDAC---------------------- 669
Query: 748 LACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQESDCGVGV 802
L +C A R P+ K++IV LQ ++T GDG ND +++++ G+ +
Sbjct: 670 LNARCFA----RVEPSHKSKIVEFLQS-FDEITAMTGDGVNDAPALKKAEIGIAM 719
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.137 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,856,577
Number of Sequences: 37866
Number of extensions: 1489555
Number of successful extensions: 4879
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 4497
Number of HSP's gapped (non-prelim): 189
length of query: 1047
length of database: 18,247,518
effective HSP length: 113
effective length of query: 934
effective length of database: 13,968,660
effective search space: 13046728440
effective search space used: 13046728440
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.