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Search of human proteins with 64225290
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
(255 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens] 517 e-147
gi|82659115 distal-less homeobox 6 [Homo sapiens] 265 3e-71
gi|84043956 distal-less homeobox 1 isoform 2 [Homo sapiens] 223 2e-58
gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens] 156 2e-38
gi|4885187 distal-less homeobox 5 [Homo sapiens] 150 1e-36
gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens] 142 3e-34
gi|4885185 distal-less homeobox 3 [Homo sapiens] 137 1e-32
gi|4758168 distal-less homeobox 2 [Homo sapiens] 133 1e-31
gi|153218470 BarH-like homeobox 1 [Homo sapiens] 84 1e-16
gi|118582284 msh homeobox 1 [Homo sapiens] 83 2e-16
gi|6633798 BarH-like homeobox 2 [Homo sapiens] 82 6e-16
gi|27886557 msh homeobox 2 [Homo sapiens] 80 2e-15
gi|39930383 BarH-like homeobox 2 [Homo sapiens] 79 3e-15
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap... 79 4e-15
gi|226437602 NK1 homeobox 2 [Homo sapiens] 78 7e-15
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens] 78 7e-15
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens] 78 7e-15
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens] 78 7e-15
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 77 1e-14
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens] 77 1e-14
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens] 77 1e-14
gi|31377777 NK2 homeobox 8 [Homo sapiens] 77 1e-14
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap... 77 1e-14
gi|147901462 brain specific homeobox [Homo sapiens] 77 2e-14
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap... 76 3e-14
gi|84570137 homeobox B3 [Homo sapiens] 75 4e-14
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens] 75 7e-14
gi|157743259 H6 family homeobox 3 [Homo sapiens] 74 2e-13
gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens] 74 2e-13
gi|89257348 homeo box HB9 [Homo sapiens] 74 2e-13
>gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
Length = 255
Score = 517 bits (1331), Expect = e-147
Identities = 255/255 (100%), Positives = 255/255 (100%)
Query: 1 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA 60
MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA
Sbjct: 1 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA 60
Query: 61 SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVR 120
SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVR
Sbjct: 61 SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVR 120
Query: 121 FNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKR 180
FNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKR
Sbjct: 121 FNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKR 180
Query: 181 SKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGNAGSYIPSYTSW 240
SKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGNAGSYIPSYTSW
Sbjct: 181 SKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGNAGSYIPSYTSW 240
Query: 241 YPSAHQEAMQQPQLM 255
YPSAHQEAMQQPQLM
Sbjct: 241 YPSAHQEAMQQPQLM 255
>gi|82659115 distal-less homeobox 6 [Homo sapiens]
Length = 265
Score = 265 bits (677), Expect = 3e-71
Identities = 148/267 (55%), Positives = 176/267 (65%), Gaps = 15/267 (5%)
Query: 1 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA 60
MTMTTM + L S K+ FMEFG QQ M+ HY +HCLHSA + G++
Sbjct: 2 MTMTTMADGLEGQDSSKSAFMEFGQQQQQQHSPAMAGAHYPLHCLHSAAAAAAAGSHHHH 61
Query: 61 SSFSRPLGYPYV----NSVS--SHASSPYISS------VQSYPGSASLAQSRLEDPGADS 108
G PY NS + S A+ PY+S +QSY S++ AQ+R +D D
Sbjct: 62 HHQHHHHGSPYASGGGNSYNHRSLAAYPYMSHSQHSPYLQSYHNSSAAAQTRGDD--TDQ 119
Query: 109 EKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLT 168
+K+TV+E GE+RFNGKGKKIRKPRTIYSSLQLQALN RFQQTQYLALPERAELAASLGLT
Sbjct: 120 QKTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLT 179
Query: 169 QTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGG 228
QTQVKIWFQNKRSKFKKL+KQG E L ALS SP +PP W+ S+S KG
Sbjct: 180 QTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPRSPALPPVWDV-SASAKGVSM 238
Query: 229 NAGSYIPSYTSWYPSAHQEAMQQPQLM 255
SY+P Y+ WY S HQ+ MQ+PQ+M
Sbjct: 239 PPNSYMPGYSHWYSSPHQDTMQRPQMM 265
>gi|84043956 distal-less homeobox 1 isoform 2 [Homo sapiens]
Length = 129
Score = 223 bits (567), Expect = 2e-58
Identities = 111/128 (86%), Positives = 113/128 (88%), Gaps = 3/128 (2%)
Query: 1 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA 60
MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA
Sbjct: 1 MTMTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSA 60
Query: 61 SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGAD---SEKSTVVEGG 117
SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPG D + V E
Sbjct: 61 SSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGQDLVPKQAIQVQEAD 120
Query: 118 EVRFNGKG 125
E + G G
Sbjct: 121 EAGWGGSG 128
>gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]
Length = 240
Score = 156 bits (394), Expect = 2e-38
Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 29/261 (11%)
Query: 3 MTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASS 62
MT++P L + KAVF + P + P+ P A S S
Sbjct: 1 MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLG--------------LSPTTAASPNLS 46
Query: 63 FSRPLG----YPYVNSVSSHASSPYISSVQSYPGSASLA--QSRLEDPGADSEKSTVV-E 115
+SRP G YPY + S Y+S Q S L ++ ADSEK + E
Sbjct: 47 YSRPYGHLLSYPYTEPANPGDS--YLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPE 104
Query: 116 GGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIW 175
E R KK+RKPRTIYSSLQLQ LN+RFQ TQYLALPERA+LAA LGLTQTQVKIW
Sbjct: 105 PSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIW 164
Query: 176 FQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWN-PNSSSGKGSGGNAGSYI 234
FQNKRSK+KKL+KQ EG ++S SPP+P W+ P + + SG Y
Sbjct: 165 FQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSG-----YG 219
Query: 235 PSYTSWYPSAHQEAMQQPQLM 255
S+ +WY + + PQ+M
Sbjct: 220 NSFGAWYQHHSSDVLASPQMM 240
>gi|4885187 distal-less homeobox 5 [Homo sapiens]
Length = 289
Score = 150 bits (379), Expect = 1e-36
Identities = 108/258 (41%), Positives = 130/258 (50%), Gaps = 48/258 (18%)
Query: 5 TMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHG------HYSMHCLHSAGHSQPDGAYS 58
T+PES S G P+ SP+ S+G Y H ++ + S P AY+
Sbjct: 36 TLPES--SATDSDYYSPTGGAPHGYCSPTSASYGKALNPYQYQYHGVNGSAGSYPAKAYA 93
Query: 59 SASSFSRPLGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGE 118
S Y SS Y G A +R+ P A ++ V E
Sbjct: 94 DYS---------------------YASSYHQYGG----AYNRV--PSATNQPEKEVTEPE 126
Query: 119 VRF-NGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQ 177
VR NGK KK+RKPRTIYSS QL AL RRFQ+TQYLALPERAELAASLGLTQTQVKIWFQ
Sbjct: 127 VRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQ 186
Query: 178 NKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGK-----------GS 226
NKRSK KK+MK G E S ++ ++ SP P W P SS +
Sbjct: 187 NKRSKIKKIMKNGEMPPEHSP-SSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPPTSN 245
Query: 227 GGNAGSYIPSYTSWYPSA 244
A SY+ + SWY SA
Sbjct: 246 QSPASSYLENSASWYTSA 263
>gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens]
Length = 168
Score = 142 bits (358), Expect = 3e-34
Identities = 81/151 (53%), Positives = 98/151 (64%), Gaps = 7/151 (4%)
Query: 107 DSEKSTVV-EGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASL 165
DSEK + E E R KK+RKPRTIYSSLQLQ LN+RFQ TQYLALPERA+LAA L
Sbjct: 23 DSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQL 82
Query: 166 GLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWN-PNSSSGK 224
GLTQTQVKIWFQNKRSK+KKL+KQ EG ++S SPP+P W+ P + +
Sbjct: 83 GLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLP 142
Query: 225 GSGGNAGSYIPSYTSWYPSAHQEAMQQPQLM 255
SG Y S+ +WY + + PQ+M
Sbjct: 143 TSG-----YGNSFGAWYQHHSSDVLASPQMM 168
>gi|4885185 distal-less homeobox 3 [Homo sapiens]
Length = 287
Score = 137 bits (344), Expect = 1e-32
Identities = 98/224 (43%), Positives = 120/224 (53%), Gaps = 23/224 (10%)
Query: 50 HSQPDGAYSSASSFSR---PLGYPYVNSVSSHASSPYISSVQSYPGSASLAQ--SRLEDP 104
+S P Y S + + P Y + +++ A + S Y AS Q + E P
Sbjct: 43 YSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQP 102
Query: 105 GADSEKSTVVEG--GEVRF-NGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAEL 161
+ +V E EVR NGK KK+RKPRTIYSS QL AL RRFQ+ QYLALPERAEL
Sbjct: 103 LPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAEL 162
Query: 162 AASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSS 221
AA LGLTQTQVKIWFQN+RSKFKKL K G LE S N +++ SPP P W+ +S
Sbjct: 163 AAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSP-NNSDSMACNSPPSPALWDTSSH 221
Query: 222 SGKGSGGN------AGSYIPSY-----TSWYPSAHQEAMQQPQL 254
S + S PSY SWY H + + P L
Sbjct: 222 STPAPARSQLPPPLPYSASPSYLDDPTNSWY---HAQNLSGPHL 262
>gi|4758168 distal-less homeobox 2 [Homo sapiens]
Length = 328
Score = 133 bits (335), Expect = 1e-31
Identities = 96/216 (44%), Positives = 114/216 (52%), Gaps = 30/216 (13%)
Query: 33 SPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRPLGYPY----VNSVSSHASSPY----- 83
S + Y + H AG G S ++ Y Y +N+V A S Y
Sbjct: 59 STATDSSYYTNQQHPAG-----GGGGGGSPYAHMGSYQYQASGLNNVPYSAKSSYDLGYT 113
Query: 84 --ISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQ 141
+S Y S+S A + E + E V NGK KK+RKPRTIYSS QL
Sbjct: 114 AAYTSYAPYGTSSSPANNEPEKEDLEPEIRIV--------NGKPKKVRKPRTIYSSFQLA 165
Query: 142 ALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALAN 201
AL RRFQ+TQYLALPERAELAASLGLTQTQVKIWFQN+RSKFKK+ K G E A+
Sbjct: 166 ALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGAS 225
Query: 202 GRALSAGSPPV--PPGWN---PNSSSGKGSGGNAGS 232
A SPPV P W+ P +G G G+ GS
Sbjct: 226 ASPPCA-SPPVSAPASWDFGVPQRMAGGGGPGSGGS 260
>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
Length = 254
Score = 84.0 bits (206), Expect = 1e-16
Identities = 50/135 (37%), Positives = 74/135 (54%), Gaps = 5/135 (3%)
Query: 69 YPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKI 128
+P S SS +++ PG+A LE + + G K KK
Sbjct: 87 FPLAPLGCSGLSSALLAAGPGLPGAAGAPHLPLEL----QLRGKLEAAGPGEPGTKAKKG 142
Query: 129 RKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMK 188
R+ RT+++ LQL L +RF++ +YL+ P+R +LA SLGL+Q QVK W+QN+R K+KK++
Sbjct: 143 RRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVL 202
Query: 189 QGGAALEGSALANGR 203
QGG LE GR
Sbjct: 203 QGG-GLESPTKPKGR 216
>gi|118582284 msh homeobox 1 [Homo sapiens]
Length = 303
Score = 83.2 bits (204), Expect = 2e-16
Identities = 65/191 (34%), Positives = 90/191 (47%), Gaps = 46/191 (24%)
Query: 24 GPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRPLGYPYVNSVSSHASSPY 83
G P+ SP P+ GH+S+ L P+ A A S +P P++ S
Sbjct: 104 GAPDAPSSPRPL--GHFSVGGLLKL----PEDALVKAESPEKPERTPWMQS--------- 148
Query: 84 ISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQAL 143
P + RL P K K RKPRT +++ QL AL
Sbjct: 149 -------PRFSPPPARRLSPPACTLRKH--------------KTNRKPRTPFTTAQLLAL 187
Query: 144 NRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGR 203
R+F+Q QYL++ ERAE ++SL LT+TQVKIWFQN+R+K K+L + A LE +
Sbjct: 188 ERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQE---AELE-------K 237
Query: 204 ALSAGSPPVPP 214
A P +PP
Sbjct: 238 LKMAAKPMLPP 248
>gi|6633798 BarH-like homeobox 2 [Homo sapiens]
Length = 279
Score = 81.6 bits (200), Expect = 6e-16
Identities = 41/90 (45%), Positives = 62/90 (68%), Gaps = 2/90 (2%)
Query: 102 EDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAEL 161
E PG ++ S+ E + + KK R+ RTI++ LQL L ++FQ+ +YL+ P+R +L
Sbjct: 109 EAPGGEALASSESETEQP--TPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDL 166
Query: 162 AASLGLTQTQVKIWFQNKRSKFKKLMKQGG 191
A SLGLTQ QVK W+QN+R K+KK++ +GG
Sbjct: 167 AQSLGLTQLQVKTWYQNRRMKWKKMVLKGG 196
>gi|27886557 msh homeobox 2 [Homo sapiens]
Length = 267
Score = 80.1 bits (196), Expect = 2e-15
Identities = 38/65 (58%), Positives = 52/65 (80%)
Query: 124 KGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKF 183
K K RKPRT +++ QL AL R+F+Q QYL++ ERAE ++SL LT+TQVKIWFQN+R+K
Sbjct: 138 KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKA 197
Query: 184 KKLMK 188
K+L +
Sbjct: 198 KRLQE 202
>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
Length = 387
Score = 79.3 bits (194), Expect = 3e-15
Identities = 75/255 (29%), Positives = 107/255 (41%), Gaps = 42/255 (16%)
Query: 25 PPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSF--------SRPLGY--PYVNS 74
PP Q P P G S +S SSF S+PL PY S
Sbjct: 116 PPQQPPPPPPQQLG------------SAASAPRTSTSSFLIKDILGDSKPLAACAPYSTS 163
Query: 75 VSSHASSPYISSVQSYPG--------SASLAQSRLEDPGADSEKSTVVEGGEVRFNG--- 123
VSS +P S + + + ED +D + E G+
Sbjct: 164 VSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRE 223
Query: 124 ----KGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNK 179
+ KK RK RT +S QL L R F++ +YL++ +R +LAA+L LT TQVK W+QN+
Sbjct: 224 SPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNR 283
Query: 180 RSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGNAGSYIPSYTS 239
R+K+K +Q LE A A + P P ++P+ S A + Y+S
Sbjct: 284 RTKWK---RQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSS 340
Query: 240 WY--PSAHQEAMQQP 252
Y P A +Q+P
Sbjct: 341 MYRTPPAPHPQLQRP 355
>gi|210147470 NK2 transcription factor related, locus 6 [Homo
sapiens]
Length = 219
Score = 79.0 bits (193), Expect = 4e-15
Identities = 43/97 (44%), Positives = 58/97 (59%), Gaps = 5/97 (5%)
Query: 124 KGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKF 183
K ++ RKPR ++S Q+ AL RRF+Q +YL+ PER LA++L LT TQVKIWFQN+R K
Sbjct: 46 KARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKC 105
Query: 184 KKLMKQGGAALEGSALANGRA-----LSAGSPPVPPG 215
K+ + L G L R + G P + PG
Sbjct: 106 KRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPG 142
>gi|226437602 NK1 homeobox 2 [Homo sapiens]
Length = 310
Score = 78.2 bits (191), Expect = 7e-15
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 12/146 (8%)
Query: 82 PYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVR-----FNGKGKKIRKPRTIYS 136
P ++ P A + ED G +S G R K R+ RT ++
Sbjct: 112 PGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFT 171
Query: 137 SLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK-------LMKQ 189
QL AL +F+ T+YL++ ER LA SL LT+TQVKIWFQN+R+K+KK +
Sbjct: 172 YEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQV 231
Query: 190 GGAALEGSALANGRALSAGSPPVPPG 215
GG A + A G +G P PPG
Sbjct: 232 GGGAPQPGAAGGGGGGGSGGSPGPPG 257
>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 78.2 bits (191), Expect = 7e-15
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 12/146 (8%)
Query: 82 PYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVR-----FNGKGKKIRKPRTIYS 136
P ++ P A + ED G +S G R K R+ RT ++
Sbjct: 134 PGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFT 193
Query: 137 SLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK-------LMKQ 189
QL AL +F+ T+YL++ ER LA SL LT+TQVKIWFQN+R+K+KK +
Sbjct: 194 YEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQV 253
Query: 190 GGAALEGSALANGRALSAGSPPVPPG 215
GG A + A G +G P PPG
Sbjct: 254 GGGAPQPGAAGGGGGGGSGGSPGPPG 279
>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 78.2 bits (191), Expect = 7e-15
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 12/146 (8%)
Query: 82 PYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVR-----FNGKGKKIRKPRTIYS 136
P ++ P A + ED G +S G R K R+ RT ++
Sbjct: 134 PGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFT 193
Query: 137 SLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK-------LMKQ 189
QL AL +F+ T+YL++ ER LA SL LT+TQVKIWFQN+R+K+KK +
Sbjct: 194 YEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQV 253
Query: 190 GGAALEGSALANGRALSAGSPPVPPG 215
GG A + A G +G P PPG
Sbjct: 254 GGGAPQPGAAGGGGGGGSGGSPGPPG 279
>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
Length = 332
Score = 78.2 bits (191), Expect = 7e-15
Identities = 52/146 (35%), Positives = 71/146 (48%), Gaps = 12/146 (8%)
Query: 82 PYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVR-----FNGKGKKIRKPRTIYS 136
P ++ P A + ED G +S G R K R+ RT ++
Sbjct: 134 PGLARSPDAPAGALASGEPCEDGGGGPVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFT 193
Query: 137 SLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK-------LMKQ 189
QL AL +F+ T+YL++ ER LA SL LT+TQVKIWFQN+R+K+KK +
Sbjct: 194 YEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQV 253
Query: 190 GGAALEGSALANGRALSAGSPPVPPG 215
GG A + A G +G P PPG
Sbjct: 254 GGGAPQPGAAGGGGGGGSGGSPGPPG 279
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 77.4 bits (189), Expect = 1e-14
Identities = 53/147 (36%), Positives = 74/147 (50%), Gaps = 24/147 (16%)
Query: 92 GSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQ 151
G+A+ A+ + + G+DS K K R+ RT ++ QL AL +F+ T+
Sbjct: 641 GTATAAKPKRKRTGSDS---------------KSGKPRRARTAFTYEQLVALENKFKATR 685
Query: 152 YLALPERAELAASLGLTQTQVKIWFQNKRSKFKK-------LMKQGGAALEGSALANGRA 204
YL++ ER LA SL LT+TQVKIWFQN+R+K+KK GG G G
Sbjct: 686 YLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGTG 745
Query: 205 LSAGSPPVPPGWNPNSSSGKGSGGNAG 231
L G P+ P +P + G G AG
Sbjct: 746 LPGGLSPLSP--SPPMGAPLGMHGPAG 770
>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 653
Score = 77.4 bits (189), Expect = 1e-14
Identities = 53/147 (36%), Positives = 74/147 (50%), Gaps = 24/147 (16%)
Query: 92 GSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQ 151
G+A+ A+ + + G+DS K K R+ RT ++ QL AL +F+ T+
Sbjct: 76 GTATAAKPKRKRTGSDS---------------KSGKPRRARTAFTYEQLVALENKFKATR 120
Query: 152 YLALPERAELAASLGLTQTQVKIWFQNKRSKFKK-------LMKQGGAALEGSALANGRA 204
YL++ ER LA SL LT+TQVKIWFQN+R+K+KK GG G G
Sbjct: 121 YLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGTG 180
Query: 205 LSAGSPPVPPGWNPNSSSGKGSGGNAG 231
L G P+ P +P + G G AG
Sbjct: 181 LPGGLSPLSP--SPPMGAPLGMHGPAG 205
>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
Length = 411
Score = 77.4 bits (189), Expect = 1e-14
Identities = 53/147 (36%), Positives = 74/147 (50%), Gaps = 24/147 (16%)
Query: 92 GSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQ 151
G+A+ A+ + + G+DS K K R+ RT ++ QL AL +F+ T+
Sbjct: 238 GTATAAKPKRKRTGSDS---------------KSGKPRRARTAFTYEQLVALENKFKATR 282
Query: 152 YLALPERAELAASLGLTQTQVKIWFQNKRSKFKK-------LMKQGGAALEGSALANGRA 204
YL++ ER LA SL LT+TQVKIWFQN+R+K+KK GG G G
Sbjct: 283 YLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGTG 342
Query: 205 LSAGSPPVPPGWNPNSSSGKGSGGNAG 231
L G P+ P +P + G G AG
Sbjct: 343 LPGGLSPLSP--SPPMGAPLGMHGPAG 367
>gi|31377777 NK2 homeobox 8 [Homo sapiens]
Length = 239
Score = 77.0 bits (188), Expect = 1e-14
Identities = 59/168 (35%), Positives = 78/168 (46%), Gaps = 25/168 (14%)
Query: 71 YVNSVSSHASSPYISSVQ-SYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIR 129
+++S H S SS++ S P S+ +R PG+D+EK +
Sbjct: 43 WLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAEKR-----------------K 85
Query: 130 KPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQ 189
K R ++S Q L RRF+Q +YL+ PER +LA+ L LT TQVKIWFQN R K K+
Sbjct: 86 KRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAP 145
Query: 190 GGAALEGSALANGRALSAG-----SPPVPPGWNPNSSSGKGSGGNAGS 232
G A E LA L A VP G G GG G+
Sbjct: 146 GAA--ESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGT 191
>gi|111120318 NK6 transcription factor related, locus 1 [Homo
sapiens]
Length = 367
Score = 77.0 bits (188), Expect = 1e-14
Identities = 59/200 (29%), Positives = 94/200 (47%), Gaps = 22/200 (11%)
Query: 7 PESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRP 66
P +N +S ++ + G SPS S S SA + A ++A++ S
Sbjct: 95 PHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPA 154
Query: 67 ---LGYPYVNSVSSHASSP---------YISSVQSYPGSASLAQSRL---------EDPG 105
G P +S+S P +++V YP + R P
Sbjct: 155 GLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPW 214
Query: 106 ADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASL 165
D+ + G + + GK+ + R +S Q+ AL + F+QT+YLA PERA LA SL
Sbjct: 215 RDARLACTPHQGSILLDKDGKR-KHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSL 273
Query: 166 GLTQTQVKIWFQNKRSKFKK 185
G+T++QVK+WFQN+R+K++K
Sbjct: 274 GMTESQVKVWFQNRRTKWRK 293
>gi|147901462 brain specific homeobox [Homo sapiens]
Length = 233
Score = 76.6 bits (187), Expect = 2e-14
Identities = 60/226 (26%), Positives = 90/226 (39%), Gaps = 67/226 (29%)
Query: 7 PESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRP 66
P+ S ++ + +++G P + P+P ++ H LH H P + + S P
Sbjct: 38 PDHFASSLASRVPLLDYGYP---LMPTPTLLAPHAHHPLHKGDHHHP--YFLTTSGMPVP 92
Query: 67 LGYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGK 126
+P+ HA P GK
Sbjct: 93 ALFPH----PQHAELP----------------------------------------GKHC 108
Query: 127 KIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKL 186
+ RK RT++S QL L +RF+ +YL+ PER ELA +L L++TQVK WFQN+R K KK
Sbjct: 109 RRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKHKKQ 168
Query: 187 MKQGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGNAGS 232
+++ S P P G P S G G A +
Sbjct: 169 LRK----------------SQDEPKAPDG--PESPEGSPRGSEAAT 196
>gi|148746211 NK2 transcription factor related, locus 3 [Homo
sapiens]
Length = 364
Score = 75.9 bits (185), Expect = 3e-14
Identities = 43/91 (47%), Positives = 57/91 (62%), Gaps = 11/91 (12%)
Query: 124 KGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKF 183
K + RKPR ++S Q+ L RRF+Q +YL+ PER LA+SL LT TQVKIWFQN+R K
Sbjct: 144 KPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKC 203
Query: 184 KKLMKQGGAALEGSALANGRALSAGSPPVPP 214
K+ ++ +LE L A +PP PP
Sbjct: 204 KR--QRQDKSLE---------LGAHAPPPPP 223
>gi|84570137 homeobox B3 [Homo sapiens]
Length = 431
Score = 75.5 bits (184), Expect = 4e-14
Identities = 50/128 (39%), Positives = 64/128 (50%), Gaps = 15/128 (11%)
Query: 129 RKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMK 188
++ RT Y+S QL L + F +YL P R E+A L L++ Q+KIWFQN+R K+KK K
Sbjct: 189 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQK 248
Query: 189 QGGAALEGSALANGRALSAGSPPVPPGWNPNSSSGKGSGGNAGSYIPSYTSWYP----SA 244
+G A ++G AGSPP P S G S PSY S P A
Sbjct: 249 -----AKGLASSSGGPSPAGSPPQP------MQSTAGFMNALHSMTPSYESPSPPAFGKA 297
Query: 245 HQEAMQQP 252
HQ A P
Sbjct: 298 HQNAYALP 305
>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
Length = 324
Score = 74.7 bits (182), Expect = 7e-14
Identities = 45/118 (38%), Positives = 62/118 (52%), Gaps = 14/118 (11%)
Query: 124 KGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKF 183
+ ++ RKPR ++S Q+ L RRF+Q +YL+ PER +LA+ L LT TQVKIWFQN+R K
Sbjct: 134 RARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKC 193
Query: 184 KKLMKQGGAALEGSALANGRALSAGSPPVPPGWN----PNSSSGKGSGGNAGSYIPSY 237
K+ + L G PP PP GK G++ Y P+Y
Sbjct: 194 KRQRQDQTLELVG----------LPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAY 241
>gi|157743259 H6 family homeobox 3 [Homo sapiens]
Length = 357
Score = 73.6 bits (179), Expect = 2e-13
Identities = 52/149 (34%), Positives = 82/149 (55%), Gaps = 10/149 (6%)
Query: 88 QSYPGSASLAQ-SRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRR 146
++ PG+A + + PGA+ K +G E + +K RT++S Q+ L
Sbjct: 190 EAAPGAAGASVGAAAATPGAEDWK----KGAESPEKKPACRKKKTRTVFSRSQVFQLEST 245
Query: 147 FQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALS 206
F +YL+ ERA LAASL LT+TQVKIWFQN+R+K+K +Q A LE + L++ A
Sbjct: 246 FDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWK---RQLAAELEAANLSHAAAQR 302
Query: 207 AGSPPVPPGWNPNSSSGKGSGGNAGSYIP 235
P+ ++ NS++ + AG+ +P
Sbjct: 303 IVRVPIL--YHENSAAEGAAAAAAGAPVP 329
>gi|4505401 NK2 transcription factor related, locus 2 [Homo sapiens]
Length = 273
Score = 73.6 bits (179), Expect = 2e-13
Identities = 43/99 (43%), Positives = 57/99 (57%), Gaps = 6/99 (6%)
Query: 93 SASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQY 152
S+S + D D++K T GG+ GKK RK R ++S Q L RRF+Q +Y
Sbjct: 99 SSSKSPEPSADESPDNDKETPGGGGDA-----GKK-RKRRVLFSKAQTYELERRFRQQRY 152
Query: 153 LALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGG 191
L+ PER LA+ + LT TQVKIWFQN R K K+ + G
Sbjct: 153 LSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKG 191
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 73.6 bits (179), Expect = 2e-13
Identities = 43/106 (40%), Positives = 59/106 (55%), Gaps = 5/106 (4%)
Query: 127 KIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKL 186
K R+PRT ++S QL L +F+ +YL+ P+R E+A SL LT+TQVKIWFQN+R K+K+
Sbjct: 240 KCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRS 299
Query: 187 MKQGGAALEGSALANGRALSAG-----SPPVPPGWNPNSSSGKGSG 227
K A + + G AG P P + KGSG
Sbjct: 300 KKAKEQAAQEAEKQKGGGGGAGKGGAEEPGAEELLGPPAPGDKGSG 345
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,347,991
Number of Sequences: 37866
Number of extensions: 573062
Number of successful extensions: 3056
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 300
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 2560
Number of HSP's gapped (non-prelim): 563
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.