Guide to the Human Genome
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Search of human proteins with 63252916

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|63252916 FERM and PDZ domain containing 2 isoform 2 [Homo
sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa...   531   e-151
gi|110346440 FERM and PDZ domain containing 2 isoform 4 [Homo sa...   531   e-151
gi|63252916 FERM and PDZ domain containing 2 isoform 2 [Homo sap...   531   e-151
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa...   531   e-151
gi|110346445 FERM and PDZ domain containing 2 like 1 isoform 4 [...   530   e-151
gi|110346443 FERM and PDZ domain containing 2 like 1 isoform 2 [...   530   e-151
gi|110346449 FERM and PDZ domain containing 2 like 2 isoform 4 [...   530   e-151
gi|110346447 FERM and PDZ domain containing 2 like 2 isoform 2 [...   530   e-151
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i...   123   1e-28
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i...   123   1e-28
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i...   123   1e-28
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is...   123   1e-28
gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]           54   1e-07
gi|4759306 lin-7 homolog A [Homo sapiens]                              53   2e-07
gi|148833504 interleukin 16 isoform 2 [Homo sapiens]                   52   4e-07
gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens]          52   4e-07
gi|8922944 lin-7 homolog C [Homo sapiens]                              52   4e-07
gi|148612825 Rap GTPase interactor [Homo sapiens]                      52   7e-07
gi|119120907 par-3 partitioning defective 3 homolog B isoform a ...    52   7e-07
gi|119120903 par-3 partitioning defective 3 homolog B isoform c ...    52   7e-07
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom...    51   9e-07
gi|11545920 lin-7 homolog B [Homo sapiens]                             51   9e-07
gi|112382257 InaD-like [Homo sapiens]                                  50   3e-06
gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens]    50   3e-06
gi|218505835 membrane-associated guanylate kinase-related  3 iso...    50   3e-06
gi|155969695 membrane-associated guanylate kinase-related  3 iso...    50   3e-06
gi|148746189 multiple PDZ domain protein [Homo sapiens]                49   4e-06
gi|119120897 par-3 partitioning defective 3 homolog B isoform b ...    49   4e-06
gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens]       49   6e-06
gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens]       49   6e-06

>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
            sapiens]
          Length = 1287

 Score =  531 bits (1368), Expect = e-151
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1    MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
            MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1027 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 1086

Query: 61   VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
            VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 1087 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 1146

Query: 121  GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
            GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 1147 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 1206

Query: 181  QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
            QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 1207 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 1266

Query: 241  IMRLGRYSFSSPLTRLSTDIF 261
            IMRLGRYSFSSPLTRLSTDIF
Sbjct: 1267 IMRLGRYSFSSPLTRLSTDIF 1287



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 35/111 (31%), Positives = 50/111 (45%), Gaps = 7/111 (6%)

Query: 14   LPGRPSSCV----SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPG 69
            L G  SSC      ++ G  + V+L K    LGFS       S  +     + +K + PG
Sbjct: 907  LKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPY---GGIYVKSIVPG 963

Query: 70   QPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
             PA + G I  GD +L V+G    GL  ++ +  L G  Q   L+L R  P
Sbjct: 964  GPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1014



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 2/84 (2%)

Query: 32  VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
           V LK++ +  GF FV  E E        +  I  + PG PAE+   I  G  ILA+N  S
Sbjct: 754 VTLKRDPHR-GFGFVINEGEYSGQADPGIF-ISSIIPGGPAEKAKTIKPGGQILALNHIS 811

Query: 92  TEGLIFQEVLHLLRGAPQEVTLLL 115
            EG  F   + +++ +P  + L++
Sbjct: 812 LEGFTFNMAVRMIQNSPDNIELII 835


>gi|110346440 FERM and PDZ domain containing 2 isoform 4 [Homo
           sapiens]
          Length = 320

 Score =  531 bits (1368), Expect = e-151
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
           MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 60  MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 119

Query: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
           VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 120 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 179

Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
           GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 180 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 239

Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
           QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 240 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 299

Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
           IMRLGRYSFSSPLTRLSTDIF
Sbjct: 300 IMRLGRYSFSSPLTRLSTDIF 320


>gi|63252916 FERM and PDZ domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 261

 Score =  531 bits (1368), Expect = e-151
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
           MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1   MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60

Query: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
           VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120

Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
           GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180

Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
           QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240

Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
           IMRLGRYSFSSPLTRLSTDIF
Sbjct: 241 IMRLGRYSFSSPLTRLSTDIF 261


>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
            sapiens]
          Length = 1309

 Score =  531 bits (1368), Expect = e-151
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1    MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
            MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1049 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 1108

Query: 61   VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
            VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 1109 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 1168

Query: 121  GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
            GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 1169 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 1228

Query: 181  QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
            QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 1229 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 1288

Query: 241  IMRLGRYSFSSPLTRLSTDIF 261
            IMRLGRYSFSSPLTRLSTDIF
Sbjct: 1289 IMRLGRYSFSSPLTRLSTDIF 1309



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 35/111 (31%), Positives = 50/111 (45%), Gaps = 7/111 (6%)

Query: 14   LPGRPSSCV----SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPG 69
            L G  SSC      ++ G  + V+L K    LGFS       S  +     + +K + PG
Sbjct: 929  LKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPY---GGIYVKSIVPG 985

Query: 70   QPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
             PA + G I  GD +L V+G    GL  ++ +  L G  Q   L+L R  P
Sbjct: 986  GPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1036



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 2/84 (2%)

Query: 32  VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
           V LK++ +  GF FV  E E        +  I  + PG PAE+   I  G  ILA+N  S
Sbjct: 776 VTLKRDPHR-GFGFVINEGEYSGQADPGIF-ISSIIPGGPAEKAKTIKPGGQILALNHIS 833

Query: 92  TEGLIFQEVLHLLRGAPQEVTLLL 115
            EG  F   + +++ +P  + L++
Sbjct: 834 LEGFTFNMAVRMIQNSPDNIELII 857


>gi|110346445 FERM and PDZ domain containing 2 like 1 isoform 4
           [Homo sapiens]
          Length = 320

 Score =  530 bits (1366), Expect = e-151
 Identities = 260/261 (99%), Positives = 261/261 (100%)

Query: 1   MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
           MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 60  MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 119

Query: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
           VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 120 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 179

Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
           GALPE+EQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 180 GALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 239

Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
           QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 240 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 299

Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
           IMRLGRYSFSSPLTRLSTDIF
Sbjct: 300 IMRLGRYSFSSPLTRLSTDIF 320


>gi|110346443 FERM and PDZ domain containing 2 like 1 isoform 2
           [Homo sapiens]
          Length = 261

 Score =  530 bits (1366), Expect = e-151
 Identities = 260/261 (99%), Positives = 261/261 (100%)

Query: 1   MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
           MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1   MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60

Query: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
           VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120

Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
           GALPE+EQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 121 GALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180

Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
           QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240

Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
           IMRLGRYSFSSPLTRLSTDIF
Sbjct: 241 IMRLGRYSFSSPLTRLSTDIF 261


>gi|110346449 FERM and PDZ domain containing 2 like 2 isoform 4
           [Homo sapiens]
          Length = 320

 Score =  530 bits (1366), Expect = e-151
 Identities = 260/261 (99%), Positives = 261/261 (100%)

Query: 1   MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
           MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 60  MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 119

Query: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
           VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 120 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 179

Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
           GALPE+EQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 180 GALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 239

Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
           QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 240 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 299

Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
           IMRLGRYSFSSPLTRLSTDIF
Sbjct: 300 IMRLGRYSFSSPLTRLSTDIF 320


>gi|110346447 FERM and PDZ domain containing 2 like 2 isoform 2
           [Homo sapiens]
          Length = 261

 Score =  530 bits (1366), Expect = e-151
 Identities = 260/261 (99%), Positives = 261/261 (100%)

Query: 1   MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
           MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1   MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60

Query: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
           VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120

Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
           GALPE+EQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 121 GALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180

Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
           QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240

Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
           IMRLGRYSFSSPLTRLSTDIF
Sbjct: 241 IMRLGRYSFSSPLTRLSTDIF 261


>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
            isoform 4 [Homo sapiens]
          Length = 2490

 Score =  123 bits (309), Expect = 1e-28
 Identities = 72/166 (43%), Positives = 97/166 (58%), Gaps = 17/166 (10%)

Query: 24   VTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDI 83
            VT+   FEVKL KN++GLGFSF + +      + + +VR+K+LFPGQPA E+G I  GD+
Sbjct: 1499 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1558

Query: 84   ILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS------- 136
            IL VNG S +GL  QEV+  LRG   EV LLLCRPPPG LPE++    TP  S       
Sbjct: 1559 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1618

Query: 137  ADKEFTRATCTDSCTSPILDQ----------EDSWRDSASPDAGEG 172
            + K+ ++ +C +  TS   ++            S RDS S  +G G
Sbjct: 1619 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSG 1664



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)

Query: 23   SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 77
            S+   P+ E   V LKK+A  GLGF  +  EK      + DL + I  + PG PA+ +G 
Sbjct: 1082 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1137

Query: 78   IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 118
            +  GD +++VN  S EG+     + +L+ AP++VTL++ +P
Sbjct: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1178



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 2/91 (2%)

Query: 27   GPKFEVKLKKNANGLGFSF-VQMEKESCS-HLKSDLVRIKRLFPGQPAEENGAIAAGDII 84
            G  FEV+L KN N LG S  V  +K   +  ++   + +K + P   AE +G I  GD +
Sbjct: 1364 GDIFEVELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRV 1423

Query: 85   LAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
            LAVNG S EG   ++ +  LR   Q V LLL
Sbjct: 1424 LAVNGVSLEGATHKQAVETLRNTGQVVHLLL 1454



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)

Query: 31   EVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
            ++ L  N   LGFS        C    S   +V I  + P   A   G +   D+I  VN
Sbjct: 1888 DITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVN 1940

Query: 89   GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADK--EFTRATC 146
            G ST+G+  +EV   L  +   + L   R     +P  ++      +SA K  +   +  
Sbjct: 1941 GVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVSAPKSTKGNGSYS 1996

Query: 147  TDSCTSPILDQEDSWRDSASPDAGE 171
              SC+ P L   DS+   A  +  E
Sbjct: 1997 VGSCSQPALTPNDSFSTVAGEEINE 2021



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)

Query: 71   PAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEW 130
            PA+ +G +  GD ++ VN      +   + ++LLR A + V L++     G + EL +  
Sbjct: 1826 PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVI-----GRVLELPRIP 1880

Query: 131  QTPELSADKEFT 142
              P L  D   T
Sbjct: 1881 MLPHLLPDITLT 1892


>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
            isoform 3 [Homo sapiens]
          Length = 2294

 Score =  123 bits (309), Expect = 1e-28
 Identities = 72/166 (43%), Positives = 97/166 (58%), Gaps = 17/166 (10%)

Query: 24   VTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDI 83
            VT+   FEVKL KN++GLGFSF + +      + + +VR+K+LFPGQPA E+G I  GD+
Sbjct: 1303 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1362

Query: 84   ILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS------- 136
            IL VNG S +GL  QEV+  LRG   EV LLLCRPPPG LPE++    TP  S       
Sbjct: 1363 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1422

Query: 137  ADKEFTRATCTDSCTSPILDQ----------EDSWRDSASPDAGEG 172
            + K+ ++ +C +  TS   ++            S RDS S  +G G
Sbjct: 1423 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSG 1468



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)

Query: 23  SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 77
           S+   P+ E   V LKK+A  GLGF  +  EK      + DL + I  + PG PA+ +G 
Sbjct: 891 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 946

Query: 78  IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 118
           +  GD +++VN  S EG+     + +L+ AP++VTL++ +P
Sbjct: 947 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 987



 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 36/89 (40%), Positives = 45/89 (50%), Gaps = 3/89 (3%)

Query: 27   GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
            G  FEV+L KN N LG S       S  H     + +K + P   AE +G I  GD +LA
Sbjct: 1173 GDIFEVELAKNDNSLGISVTGGVNTSVRH---GGIYVKAVIPQGAAESDGRIHKGDRVLA 1229

Query: 87   VNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
            VNG S EG   ++ +  LR   Q V LLL
Sbjct: 1230 VNGVSLEGATHKQAVETLRNTGQVVHLLL 1258



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)

Query: 31   EVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
            ++ L  N   LGFS        C    S   +V I  + P   A   G +   D+I  VN
Sbjct: 1692 DITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVN 1744

Query: 89   GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADK--EFTRATC 146
            G ST+G+  +EV   L  +   + L   R     +P  ++      +SA K  +   +  
Sbjct: 1745 GVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVSAPKSTKGNGSYS 1800

Query: 147  TDSCTSPILDQEDSWRDSASPDAGE 171
              SC+ P L   DS+   A  +  E
Sbjct: 1801 VGSCSQPALTPNDSFSTVAGEEINE 1825



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)

Query: 71   PAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEW 130
            PA+ +G +  GD ++ VN      +   + ++LLR A + V L++     G + EL +  
Sbjct: 1630 PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVI-----GRVLELPRIP 1684

Query: 131  QTPELSADKEFT 142
              P L  D   T
Sbjct: 1685 MLPHLLPDITLT 1696


>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
            isoform 1 [Homo sapiens]
          Length = 2485

 Score =  123 bits (309), Expect = 1e-28
 Identities = 72/166 (43%), Positives = 97/166 (58%), Gaps = 17/166 (10%)

Query: 24   VTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDI 83
            VT+   FEVKL KN++GLGFSF + +      + + +VR+K+LFPGQPA E+G I  GD+
Sbjct: 1494 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1553

Query: 84   ILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS------- 136
            IL VNG S +GL  QEV+  LRG   EV LLLCRPPPG LPE++    TP  S       
Sbjct: 1554 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1613

Query: 137  ADKEFTRATCTDSCTSPILDQ----------EDSWRDSASPDAGEG 172
            + K+ ++ +C +  TS   ++            S RDS S  +G G
Sbjct: 1614 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSG 1659



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)

Query: 23   SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 77
            S+   P+ E   V LKK+A  GLGF  +  EK      + DL + I  + PG PA+ +G 
Sbjct: 1082 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1137

Query: 78   IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 118
            +  GD +++VN  S EG+     + +L+ AP++VTL++ +P
Sbjct: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1178



 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 36/89 (40%), Positives = 45/89 (50%), Gaps = 3/89 (3%)

Query: 27   GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
            G  FEV+L KN N LG S       S  H     + +K + P   AE +G I  GD +LA
Sbjct: 1364 GDIFEVELAKNDNSLGISVTGGVNTSVRH---GGIYVKAVIPQGAAESDGRIHKGDRVLA 1420

Query: 87   VNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
            VNG S EG   ++ +  LR   Q V LLL
Sbjct: 1421 VNGVSLEGATHKQAVETLRNTGQVVHLLL 1449



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)

Query: 31   EVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
            ++ L  N   LGFS        C    S   +V I  + P   A   G +   D+I  VN
Sbjct: 1883 DITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVN 1935

Query: 89   GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADK--EFTRATC 146
            G ST+G+  +EV   L  +   + L   R     +P  ++      +SA K  +   +  
Sbjct: 1936 GVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVSAPKSTKGNGSYS 1991

Query: 147  TDSCTSPILDQEDSWRDSASPDAGE 171
              SC+ P L   DS+   A  +  E
Sbjct: 1992 VGSCSQPALTPNDSFSTVAGEEINE 2016



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)

Query: 71   PAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEW 130
            PA+ +G +  GD ++ VN      +   + ++LLR A + V L++     G + EL +  
Sbjct: 1821 PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVI-----GRVLELPRIP 1875

Query: 131  QTPELSADKEFT 142
              P L  D   T
Sbjct: 1876 MLPHLLPDITLT 1887


>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
            2 [Homo sapiens]
          Length = 2466

 Score =  123 bits (309), Expect = 1e-28
 Identities = 72/166 (43%), Positives = 97/166 (58%), Gaps = 17/166 (10%)

Query: 24   VTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDI 83
            VT+   FEVKL KN++GLGFSF + +      + + +VR+K+LFPGQPA E+G I  GD+
Sbjct: 1475 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1534

Query: 84   ILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS------- 136
            IL VNG S +GL  QEV+  LRG   EV LLLCRPPPG LPE++    TP  S       
Sbjct: 1535 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1594

Query: 137  ADKEFTRATCTDSCTSPILDQ----------EDSWRDSASPDAGEG 172
            + K+ ++ +C +  TS   ++            S RDS S  +G G
Sbjct: 1595 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSG 1640



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)

Query: 23   SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 77
            S+   P+ E   V LKK+A  GLGF  +  EK      + DL + I  + PG PA+ +G 
Sbjct: 1063 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1118

Query: 78   IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 118
            +  GD +++VN  S EG+     + +L+ AP++VTL++ +P
Sbjct: 1119 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1159



 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 36/89 (40%), Positives = 45/89 (50%), Gaps = 3/89 (3%)

Query: 27   GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
            G  FEV+L KN N LG S       S  H     + +K + P   AE +G I  GD +LA
Sbjct: 1345 GDIFEVELAKNDNSLGISVTGGVNTSVRH---GGIYVKAVIPQGAAESDGRIHKGDRVLA 1401

Query: 87   VNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
            VNG S EG   ++ +  LR   Q V LLL
Sbjct: 1402 VNGVSLEGATHKQAVETLRNTGQVVHLLL 1430



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)

Query: 31   EVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
            ++ L  N   LGFS        C    S   +V I  + P   A   G +   D+I  VN
Sbjct: 1864 DITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVN 1916

Query: 89   GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADK--EFTRATC 146
            G ST+G+  +EV   L  +   + L   R     +P  ++      +SA K  +   +  
Sbjct: 1917 GVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVSAPKSTKGNGSYS 1972

Query: 147  TDSCTSPILDQEDSWRDSASPDAGE 171
              SC+ P L   DS+   A  +  E
Sbjct: 1973 VGSCSQPALTPNDSFSTVAGEEINE 1997



 Score = 31.2 bits (69), Expect = 0.95
 Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)

Query: 71   PAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEW 130
            PA+ +G +  GD ++ VN      +   + ++LLR A + V L++     G + EL +  
Sbjct: 1802 PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVI-----GRVLELPRIP 1856

Query: 131  QTPELSADKEFT 142
              P L  D   T
Sbjct: 1857 MLPHLLPDITLT 1868


>gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]
          Length = 1434

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 40/97 (41%), Positives = 50/97 (51%), Gaps = 14/97 (14%)

Query: 35  KKNANGLGFSFVQMEKESCSH---LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
           K+   GLGF    + KE  S    + SDL+R      G  AE++G I AGDIILAVNGR 
Sbjct: 22  KRKVGGLGF----LVKERVSKPPVIISDLIR------GGAAEQSGLIQAGDIILAVNGRP 71

Query: 92  TEGLIFQEVLHLLRGAPQEV-TLLLCRPPPGALPELE 127
              L +   L +LRG   E   +L+ R P G    LE
Sbjct: 72  LVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLE 108


>gi|4759306 lin-7 homolog A [Homo sapiens]
          Length = 233

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 33/100 (33%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 32  VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
           V+L K   GLGF+ +  ++++        + I R+ PG  AE +G +  GD +L+VNG S
Sbjct: 109 VELPKTDEGLGFNVMGGKEQNSP------IYISRIIPGGVAERHGGLKRGDQLLSVNGVS 162

Query: 92  TEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQ 131
            EG   ++ + LL+ A   V L++ R  P  L E+E  ++
Sbjct: 163 VEGEHHEKAVELLKAAKDSVKLVV-RYTPKVLEEMEARFE 201


>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
          Length = 1332

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 30/103 (29%), Positives = 55/103 (53%), Gaps = 7/103 (6%)

Query: 26   DGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIIL 85
            DG    +  K+   GLGFS         + L++ ++ + R+FP   A + G I  G+ +L
Sbjct: 1109 DGIHVTILHKEEGAGLGFSLA-----GGADLENKVITVHRVFPNGLASQEGTIQKGNEVL 1163

Query: 86   AVNGRSTEGLIFQEVLHLLRGA--PQEVTLLLCRPPPGALPEL 126
            ++NG+S +G    + L +LR A  P++  ++  +  P A+P+L
Sbjct: 1164 SINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDL 1206



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 53/184 (28%), Positives = 81/184 (44%), Gaps = 14/184 (7%)

Query: 2   GDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLV 61
           G  R   SL TA   +PS  +  +      V +K  A GLGFS V  +      +    +
Sbjct: 189 GTSRPTRSLSTAQLVQPSGGLQASVISNI-VLMKGQAKGLGFSIVGGKDSIYGPIG---I 244

Query: 62  RIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPG 121
            +K +F G  A  +G +  GD IL +NG S  GL  Q+ L   + A + +  L  R    
Sbjct: 245 YVKTIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRLT 304

Query: 122 ALPELEQEWQTP---ELSADKEFTRATCT---DSCTSPILDQEDSWR----DSASPDAGE 171
           A P L      P    LS+    T+ + +   +S ++PI   + ++R     S   +AG 
Sbjct: 305 APPSLCSHLSPPLCRSLSSSTCITKDSSSFALESPSAPISTAKPNYRIMVEVSLQKEAGV 364

Query: 172 GLGL 175
           GLG+
Sbjct: 365 GLGI 368



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)

Query: 9    SLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFP 68
            S  +A      S  S  +     V L+K + GLGFS   +E    S      + I R+F 
Sbjct: 1212 SAASASAASDVSVESTAEATVCTVTLEKMSAGLGFS---LEGGKGSLHGDKPLTINRIFK 1268

Query: 69   GQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQ-EVTLLLCR 117
            G  +E++  +  GD IL + G + +GL   E  ++++  P   VT+++ R
Sbjct: 1269 GAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRR 1318



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 44/197 (22%), Positives = 72/197 (36%), Gaps = 12/197 (6%)

Query: 15  PGRPSSCVSVTDGPKFEVKLKKNAN-GLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAE 73
           P  P S          EV L+K A  GLG     +    C       + +  L PG  A 
Sbjct: 339 PSAPISTAKPNYRIMVEVSLQKEAGVGLGIGLCSVPYFQCI----SGIFVHTLSPGSVAH 394

Query: 74  ENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGA-PQEVTLLLCRPPPGALPELEQEWQT 132
            +G +  GD I+ ++      L   EV  +L    P  V +++ R P   + E + +   
Sbjct: 395 LDGRLRCGDEIVEISDSPVHCLTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLKEAV 454

Query: 133 PELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQN 192
            +   + +F +     S    +   E SW    + +       R ++S    R AQ    
Sbjct: 455 AQAVENTKFGKERHQWSLEG-VKRLESSWHGRPTLEKE-----REKNSAPPHRRAQKVMI 508

Query: 193 RERPWASSLTHSPESHP 209
           R    +S ++ SP   P
Sbjct: 509 RSSSDSSYMSGSPGGSP 525


>gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens]
          Length = 631

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 30/103 (29%), Positives = 55/103 (53%), Gaps = 7/103 (6%)

Query: 26  DGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIIL 85
           DG    +  K+   GLGFS         + L++ ++ + R+FP   A + G I  G+ +L
Sbjct: 408 DGIHVTILHKEEGAGLGFSLA-----GGADLENKVITVHRVFPNGLASQEGTIQKGNEVL 462

Query: 86  AVNGRSTEGLIFQEVLHLLRGA--PQEVTLLLCRPPPGALPEL 126
           ++NG+S +G    + L +LR A  P++  ++  +  P A+P+L
Sbjct: 463 SINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDL 505



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)

Query: 9   SLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFP 68
           S  +A      S  S  +     V L+K + GLGFS   +E    S      + I R+F 
Sbjct: 511 SAASASAASDVSVESTAEATVCTVTLEKMSAGLGFS---LEGGKGSLHGDKPLTINRIFK 567

Query: 69  GQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQ-EVTLLLCR 117
           G  +E++  +  GD IL + G + +GL   E  ++++  P   VT+++ R
Sbjct: 568 GAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRR 617


>gi|8922944 lin-7 homolog C [Homo sapiens]
          Length = 197

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 32/100 (32%), Positives = 56/100 (56%), Gaps = 7/100 (7%)

Query: 32  VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
           V+L K   GLGF+ +  ++++        + I R+ PG  A+ +G +  GD +L+VNG S
Sbjct: 94  VELPKTEEGLGFNIMGGKEQNSP------IYISRIIPGGIADRHGGLKRGDQLLSVNGVS 147

Query: 92  TEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQ 131
            EG   ++ + LL+ A  +V L++ R  P  L E+E  ++
Sbjct: 148 VEGEHHEKAVELLKAAQGKVKLVV-RYTPKVLEEMESRFE 186


>gi|148612825 Rap GTPase interactor [Homo sapiens]
          Length = 1075

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 5/116 (4%)

Query: 4    ERTAVSLVTALPGRPSSCVSVTDG--PKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLV 61
            E  + +L    P  PSS  S T+     F V+L++  +GLG   +       +HL +  +
Sbjct: 947  EGDSAALAEESPPAPSSRSSSTEDFCYVFTVELERGPSGLGMGLIDGMH---THLGAPGL 1003

Query: 62   RIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
             I+ L PG PA  +G ++ GD IL VNG S  GL +   + L+R   +++  L+ +
Sbjct: 1004 YIQTLLPGSPAAADGRLSLGDRILEVNGSSLLGLGYLRAVDLIRHGGKKMRFLVAK 1059


>gi|119120907 par-3 partitioning defective 3 homolog B isoform a
           [Homo sapiens]
          Length = 1104

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 57/183 (31%), Positives = 83/183 (45%), Gaps = 28/183 (15%)

Query: 11  VTALPGRPSSCV--------SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVR 62
           V  L G+PSS          S  +  K ++ LKK   GLGF+ V   ++S  H    +  
Sbjct: 355 VPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVT--RDSSIHGPGPIF- 411

Query: 63  IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVT--LLLCRPPP 120
           +K + P   A ++G + +GD IL VNGR   G   +E++ +LR   Q  T  L++ R   
Sbjct: 412 VKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEG 471

Query: 121 GALP-ELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPES 179
             LP EL+ E     LS +            TS  L  E    DS S  AG G+ L+   
Sbjct: 472 HFLPRELKGEPDCCALSLE------------TSEQLTFEIPLNDSGS--AGLGVSLKGNK 517

Query: 180 SQK 182
           S++
Sbjct: 518 SRE 520


>gi|119120903 par-3 partitioning defective 3 homolog B isoform c
           [Homo sapiens]
          Length = 1136

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 57/183 (31%), Positives = 83/183 (45%), Gaps = 28/183 (15%)

Query: 11  VTALPGRPSSCV--------SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVR 62
           V  L G+PSS          S  +  K ++ LKK   GLGF+ V   ++S  H    +  
Sbjct: 355 VPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVT--RDSSIHGPGPIF- 411

Query: 63  IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVT--LLLCRPPP 120
           +K + P   A ++G + +GD IL VNGR   G   +E++ +LR   Q  T  L++ R   
Sbjct: 412 VKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEG 471

Query: 121 GALP-ELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPES 179
             LP EL+ E     LS +            TS  L  E    DS S  AG G+ L+   
Sbjct: 472 HFLPRELKGEPDCCALSLE------------TSEQLTFEIPLNDSGS--AGLGVSLKGNK 517

Query: 180 SQK 182
           S++
Sbjct: 518 SRE 520


>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
            containing 2 [Homo sapiens]
          Length = 1455

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 36/110 (32%), Positives = 52/110 (47%), Gaps = 9/110 (8%)

Query: 30   FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
            F V ++K A G GFS            K DL  + RL    PA  NG +  GD I+ +NG
Sbjct: 1146 FTVDMEKGAKGFGFSI-----RGGREYKMDLY-VLRLAEDGPAIRNGRMRVGDQIIEING 1199

Query: 90   RSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQ--EWQTPELSA 137
             ST  +     + L++   + V LLL R   G +PE ++   W +P  +A
Sbjct: 1200 ESTRDMTHARAIELIKSGGRRVRLLLKR-GTGQVPEYDEPAPWSSPAAAA 1248



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 10/102 (9%)

Query: 42   GFSFVQMEKESCSHLKSDLV---RIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQ 98
            GF FV +   +     S +    +I R+  G PA+    +  GD ILAVNG+S   +   
Sbjct: 930  GFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHA 989

Query: 99   EVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADKE 140
            +++ L++ A   VTL +       +P+ E    T   S++K+
Sbjct: 990  DIVKLIKDAGLSVTLRI-------IPQEELNSPTSAPSSEKQ 1024


>gi|11545920 lin-7 homolog B [Homo sapiens]
          Length = 207

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 32  VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
           V+L K   GLGF+ +  ++++        + I R+ PG  A+ +G +  GD +L+VNG S
Sbjct: 94  VELPKTDEGLGFNIMGGKEQNSP------IYISRVIPGGVADRHGGLKRGDQLLSVNGVS 147

Query: 92  TEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQ 131
            EG   ++ + LL+ A   V L++ R  P  L E+E  ++
Sbjct: 148 VEGEQHEKAVELLKAAQGSVKLVV-RYTPRVLEEMEARFE 186


>gi|112382257 InaD-like [Homo sapiens]
          Length = 1801

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 8/91 (8%)

Query: 31  EVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGR 90
           EV+L  + +GLGF  V          K+  V ++ + PG  A+ +G +  GD IL + G 
Sbjct: 248 EVELINDGSGLGFGIVGG--------KTSGVVVRTIVPGGLADRDGRLQTGDHILKIGGT 299

Query: 91  STEGLIFQEVLHLLRGAPQEVTLLLCRPPPG 121
           + +G+  ++V  +LR     V +L+ R P G
Sbjct: 300 NVQGMTSEQVAQVLRNCGNSVRMLVARDPAG 330



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 35/110 (31%), Positives = 53/110 (48%), Gaps = 2/110 (1%)

Query: 8   VSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLF 67
           V+L T     P S  S+ +    E+ ++K+   LG   V     S +   S +  +K + 
Sbjct: 344 VALPTVASKGPGSDSSLFETYNVEL-VRKDGQSLGIRIVGYVGTSHTGEASGIY-VKSII 401

Query: 68  PGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
           PG  A  NG I   D I+AV+G + +G    +V+ +LR A Q V L L R
Sbjct: 402 PGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVVEVLRNAGQVVHLTLVR 451



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 6/100 (6%)

Query: 18   PSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGA 77
            P++C  +  G +  +++ K  +GLG S V  +    +      + I  ++    A  +G 
Sbjct: 1425 PATC-PIVPGQEMIIEISKGRSGLGLSIVGGKDTPLN-----AIVIHEVYEEGAAARDGR 1478

Query: 78   IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
            + AGD IL VNG        +E +  LR  PQ+V L++ R
Sbjct: 1479 LWAGDQILEVNGVDLRNSSHEEAITALRQTPQKVRLVVYR 1518



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 3/133 (2%)

Query: 32  VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
           V+L K+  GLGFS +  + +     +S +V I+ L     AE +G +  GD +++VN   
Sbjct: 687 VELVKDCKGLGFSILDYQ-DPLDPTRSVIV-IRSLVADGVAERSGGLLPGDRLVSVNEYC 744

Query: 92  TEGLIFQEVLHLLRGAPQE-VTLLLCRPPPGALPELEQEWQTPELSADKEFTRATCTDSC 150
            +     E + +L+  P   V L +C+P      E          + DK     T  D  
Sbjct: 745 LDNTSLAEAVEILKAVPPGLVHLGICKPLVEDNEEESCYILHSSSNEDKTEFSGTIHDIN 804

Query: 151 TSPILDQEDSWRD 163
           +S IL+    +RD
Sbjct: 805 SSLILEAPKGFRD 817



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 19/123 (15%)

Query: 32   VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
            ++L+K+ NGLG S    +  S        + +  + P  PA  +G +  GD +L +N + 
Sbjct: 1240 IELEKDKNGLGLSLAGNKDRSRMS-----IFVVGINPEGPAAADGRMRIGDELLEINNQI 1294

Query: 92   TEGLIFQEVLHLLRGAPQEVTLLLCR-------------PPPGALP-ELEQEWQTPELSA 137
              G   Q    +++ AP +V L+  R             P P + P  +E +  T  +S+
Sbjct: 1295 LYGRSHQNASAIIKTAPSKVKLVFIRNEDAVNQMAVTPFPVPSSSPSSIEDQSGTEPISS 1354

Query: 138  DKE 140
            +++
Sbjct: 1355 EED 1357



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 35  KKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS-TE 93
           + +  GLGFS V +  ++   +    + +K + PG  A+ +  +   D ILA+N     +
Sbjct: 139 RPSTGGLGFSVVALRSQNLGKVD---IFVKDVQPGSVADRDQRLKENDQILAINHTPLDQ 195

Query: 94  GLIFQEVLHLLRGAPQEVTLLLCRPP 119
            +  Q+ + LL+     + L++ R P
Sbjct: 196 NISHQQAIALLQQTTGSLRLIVAREP 221



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 17/55 (30%), Positives = 25/55 (45%)

Query: 63  IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
           I  +  G P +  G +   D +L VNG    G   +E +  L+  P   TL+ CR
Sbjct: 583 ISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLVCCR 637



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 8/94 (8%)

Query: 30   FEVKLKKNAN-GLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
            F V L+K A  GLG S V     S   + SD+V+      G  A+ +G +  GD IL+VN
Sbjct: 1532 FPVDLQKKAGRGLGLSIVGKRNGSGVFI-SDIVK------GGAADLDGRLIQGDQILSVN 1584

Query: 89   GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGA 122
            G        + V  +L+ A   V L + R   G+
Sbjct: 1585 GEDMRNASQETVATILKCAQGLVQLEIGRLRAGS 1618



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 14/53 (26%), Positives = 25/53 (47%)

Query: 63   IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
            IK++    PA +  A+  GD IL V+G   +     E +  ++ A   V  ++
Sbjct: 1104 IKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASHSEAVEAIKNAGNPVVFIV 1156



 Score = 28.1 bits (61), Expect = 8.1
 Identities = 12/36 (33%), Positives = 23/36 (63%)

Query: 78   IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTL 113
            +  GD I+++NG+  +GL   +V++LL+ A   + L
Sbjct: 1721 LKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIIL 1756


>gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens]
          Length = 1356

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 47/167 (28%), Positives = 75/167 (44%), Gaps = 8/167 (4%)

Query: 27  GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
           G +  ++LKK   GLGFS    +        S  + +K + P   A ++G + AGD ++ 
Sbjct: 457 GKRLNIQLKKGTEGLGFSITSRDVTIGG---SAPIYVKNILPRGAAIQDGRLKAGDRLIE 513

Query: 87  VNGRSTEGLIFQEVLHLLRGAPQE--VTLLLCRPPPGALPELEQEWQTPELSADKEFTRA 144
           VNG    G   +EV+ LLR    E  V+LL+ R      P  E   +  ++   KE T+A
Sbjct: 514 VNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPR-ELNAEPSQMQIPKE-TKA 571

Query: 145 TCTDSCTSPILDQEDSWRDSASPDAGE-GLGLRPESSQKAIREAQWG 190
              D   +P   +E    +    D+G  GLG+  + ++     A  G
Sbjct: 572 EDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLG 618


>gi|218505835 membrane-associated guanylate kinase-related  3
           isoform 1 [Homo sapiens]
          Length = 1481

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 43/179 (24%), Positives = 81/179 (45%), Gaps = 23/179 (12%)

Query: 27  GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
           G      LKK+  G GF+ +  ++        + +++K +    PA ++G IA GD+I+ 
Sbjct: 406 GVLVRASLKKSTMGFGFTIIGGDRPD------EFLQVKNVLKDGPAAQDGKIAPGDVIVD 459

Query: 87  VNGRSTEGLIFQEVLHLLRGAP--QEVTLLLCRPPPGALPELEQEWQTPELSADKEFTRA 144
           +NG    G    +V+ + +  P  Q V L LCR  P  LP+  ++     ++A       
Sbjct: 460 INGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYP--LPDDSEDPVVDIVAATPVINGQ 517

Query: 145 TCT--DSCTSP--------ILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQNR 193
           + T  ++C +P        +L+Q      S     G+GL    ++S++ +  A  G ++
Sbjct: 518 SLTKGETCMNPQDFKPGAMVLEQNGK---SGHTLTGDGLNGPSDASEQRVSMASSGSSQ 573



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 7/96 (7%)

Query: 30   FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
            + V+L++   G GFS    ++ +        + I RL    PA ++G I  GD I+ +NG
Sbjct: 1020 YPVELERGPRGFGFSLRGGKEYNMG------LFILRLAEDGPAIKDGRIHVGDQIVEING 1073

Query: 90   RSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPE 125
              T+G+     + L++    +V LLL RP  G +P+
Sbjct: 1074 EPTQGITHTRAIELIQAGGNKV-LLLLRPGTGLIPD 1108



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 30  FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
           ++V L++  N  GF FV +  ++         +I R+  G PA+  G +  GD I AVNG
Sbjct: 850 YDVVLQRKENE-GFGFVILTSKNKPPPGVIPHKIGRVIEGSPADRCGKLKVGDHISAVNG 908

Query: 90  RSTEGLIFQEVLHLLRGAPQEVTL 113
           +S   L    ++ L++ A   VTL
Sbjct: 909 QSIVELSHDNIVQLIKDAGVTVTL 932


>gi|155969695 membrane-associated guanylate kinase-related  3
           isoform 2 [Homo sapiens]
          Length = 1125

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 43/179 (24%), Positives = 81/179 (45%), Gaps = 23/179 (12%)

Query: 27  GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
           G      LKK+  G GF+ +  ++        + +++K +    PA ++G IA GD+I+ 
Sbjct: 406 GVLVRASLKKSTMGFGFTIIGGDRPD------EFLQVKNVLKDGPAAQDGKIAPGDVIVD 459

Query: 87  VNGRSTEGLIFQEVLHLLRGAP--QEVTLLLCRPPPGALPELEQEWQTPELSADKEFTRA 144
           +NG    G    +V+ + +  P  Q V L LCR  P  LP+  ++     ++A       
Sbjct: 460 INGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYP--LPDDSEDPVVDIVAATPVINGQ 517

Query: 145 TCT--DSCTSP--------ILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQNR 193
           + T  ++C +P        +L+Q      S     G+GL    ++S++ +  A  G ++
Sbjct: 518 SLTKGETCMNPQDFKPGAMVLEQNGK---SGHTLTGDGLNGPSDASEQRVSMASSGSSQ 573



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 7/96 (7%)

Query: 30   FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
            + V+L++   G GFS    ++ +        + I RL    PA ++G I  GD I+ +NG
Sbjct: 1020 YPVELERGPRGFGFSLRGGKEYNMG------LFILRLAEDGPAIKDGRIHVGDQIVEING 1073

Query: 90   RSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPE 125
              T+G+     + L++    +V LLL RP  G +P+
Sbjct: 1074 EPTQGITHTRAIELIQAGGNKV-LLLLRPGTGLIPD 1108



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 30  FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
           ++V L++  N  GF FV +  ++         +I R+  G PA+  G +  GD I AVNG
Sbjct: 850 YDVVLQRKENE-GFGFVILTSKNKPPPGVIPHKIGRVIEGSPADRCGKLKVGDHISAVNG 908

Query: 90  RSTEGLIFQEVLHLLRGAPQEVTL 113
           +S   L    ++ L++ A   VTL
Sbjct: 909 QSIVELSHDNIVQLIKDAGVTVTL 932


>gi|148746189 multiple PDZ domain protein [Homo sapiens]
          Length = 2041

 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 11/98 (11%)

Query: 18   PSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGA 77
            P  C S+T        L++  +GLGFS V         L    + +K +F    A E+G 
Sbjct: 1953 PPQCKSIT--------LERGPDGLGFSIVGGYGSPHGDLP---IYVKTVFAKGAASEDGR 2001

Query: 78   IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
            +  GD I+AVNG+S EG+  +E + +L+     VTL++
Sbjct: 2002 LKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMV 2039



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 36/125 (28%), Positives = 57/125 (45%), Gaps = 12/125 (9%)

Query: 3   DERTA-VSLVTALPGRPSSCVSVT---------DGPKFEVKLKKNANGLGFSFVQMEKES 52
           +ERTA  +L   L   P+S   +          +   F+V+L KN  GLG +      + 
Sbjct: 339 EERTAPTALGITLSSSPTSTPELRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDK 398

Query: 53  CSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVT 112
              L+   + +K +      E +G I  GD I+AV+G + +G   Q+ + +LR   Q V 
Sbjct: 399 --KLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVL 456

Query: 113 LLLCR 117
           L L R
Sbjct: 457 LTLMR 461



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 28/90 (31%), Positives = 50/90 (55%), Gaps = 3/90 (3%)

Query: 32  VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
           ++L+K + GLGFS   ++ +      S ++ I+ L PG  AE++G +  GD ++ VN  +
Sbjct: 701 IELEKGSKGLGFSI--LDYQDPIDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVN 758

Query: 92  TEGLIFQEVLHLLRGAPQ-EVTLLLCRPPP 120
            E    +E +  L+GAP   V + + +P P
Sbjct: 759 LENSSLEEAVEALKGAPSGTVRIGVAKPLP 788



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 7/94 (7%)

Query: 34  LKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTE 93
           LK  + GLGFS V +  E+   L    + ++ +  G  A  +G +   D ILA+NG++ +
Sbjct: 141 LKPPSGGLGFSVVGLRSENRGELG---IFVQEIQEGSVAHRDGRLKETDQILAINGQALD 197

Query: 94  GLI-FQEVLHLLRGAPQEVTLLLCRPPPGALPEL 126
             I  Q+ + +L+ A   V L++ R   G+LP+L
Sbjct: 198 QTITHQQAISILQKAKDTVQLVIAR---GSLPQL 228



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 24/67 (35%), Positives = 39/67 (58%), Gaps = 2/67 (2%)

Query: 63  IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR--PPP 120
           I+ + P  P   +G + +GD +L VNG +  G   Q+V+++L+  P EVT++ CR   PP
Sbjct: 578 IRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPP 637

Query: 121 GALPELE 127
               EL+
Sbjct: 638 TTQSELD 644



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 11/94 (11%)

Query: 32  VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
           ++L  + +GLGF  +          K+  V +K + PG  A+++G + +GD IL +    
Sbjct: 258 IELVNDGSGLGFGIIGG--------KATGVIVKTILPGGVADQHGRLCSGDHILKIGDTD 309

Query: 92  TEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPE 125
             G+  ++V  +LR     V L++ R   GA+ E
Sbjct: 310 LAGMSSEQVAQVLRQCGNRVKLMIAR---GAIEE 340



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 6/100 (6%)

Query: 18   PSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGA 77
            P++C  +  G +  +++ K   GLG S V       S      + I  ++    A ++G 
Sbjct: 1617 PATC-PIIPGCETTIEISKGRTGLGLSIV-----GGSDTLLGAIIIHEVYEEGAACKDGR 1670

Query: 78   IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
            + AGD IL VNG         E +++LR  PQ V L L R
Sbjct: 1671 LWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYR 1710



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 5/86 (5%)

Query: 32   VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
            ++L+K  +GLG S    +  S        V I  + P   A ++G +   D +L +NG+ 
Sbjct: 1351 IELEKGHSGLGLSLAGNKDRSRMS-----VFIVGIDPNGAAGKDGRLQIADELLEINGQI 1405

Query: 92   TEGLIFQEVLHLLRGAPQEVTLLLCR 117
              G   Q    +++ AP +V ++  R
Sbjct: 1406 LYGRSHQNASSIIKCAPSKVKIIFIR 1431



 Score = 31.6 bits (70), Expect = 0.73
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 4/68 (5%)

Query: 63   IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTL----LLCRP 118
            IK +    PA +NG +  GD I+ V+G        ++ +  +R A   V      ++ RP
Sbjct: 1187 IKHVLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRP 1246

Query: 119  PPGALPEL 126
                LP L
Sbjct: 1247 RKSPLPSL 1254



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 7/71 (9%)

Query: 35   KKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEG 94
            KK   GLG S V    ++   + SD+V+      G  A+ +G +  GD IL VNG     
Sbjct: 1730 KKPGKGLGLSIVGKRNDTGVFV-SDIVK------GGIADADGRLMQGDQILMVNGEDVRN 1782

Query: 95   LIFQEVLHLLR 105
               + V  LL+
Sbjct: 1783 ATQEAVAALLK 1793



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 7/84 (8%)

Query: 32   VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
            ++L K+  GLG +    E+++ S      V IK L     A  +G +  GD ILAV+   
Sbjct: 1484 LELPKDQGGLGIAI--SEEDTLSG-----VIIKSLTEHGVAATDGRLKVGDQILAVDDEI 1536

Query: 92   TEGLIFQEVLHLLRGAPQEVTLLL 115
              G   ++ + LL+ A   V L +
Sbjct: 1537 VVGYPIEKFISLLKTAKMTVKLTI 1560



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 14/51 (27%), Positives = 26/51 (50%)

Query: 63   IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTL 113
            I  + P   A +   +  GD I+ + G STEG+   + ++LL+ A   + +
Sbjct: 1863 IAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEM 1913


>gi|119120897 par-3 partitioning defective 3 homolog B isoform b
           [Homo sapiens]
          Length = 1143

 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 13/124 (10%)

Query: 11  VTALPGRPSSCV--------SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVR 62
           V  L G+PSS          S  +  K ++ LKK   GLGF+ V   ++S  H    +  
Sbjct: 355 VPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVT--RDSSIHGPGPIF- 411

Query: 63  IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVT--LLLCRPPP 120
           +K + P   A ++G + +GD IL VNGR   G   +E++ +LR   Q  T  L++ R   
Sbjct: 412 VKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEG 471

Query: 121 GALP 124
             LP
Sbjct: 472 HFLP 475


>gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens]
          Length = 728

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 4/90 (4%)

Query: 31  EVKLKKNANG-LGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
           ++ L++N  G LGF  V   +E   +  +    IK +  G PA  +G I  GDI+LAVNG
Sbjct: 638 DIVLRRNTAGSLGFCIVGGYEE---YNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNG 694

Query: 90  RSTEGLIFQEVLHLLRGAPQEVTLLLCRPP 119
           RST G+I   +  LL+     +TL +   P
Sbjct: 695 RSTSGMIHACLARLLKELKGRITLTIVSWP 724



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 18/69 (26%), Positives = 32/69 (46%)

Query: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
           V I  +  G  A  +G +   D +LA+NG        +   HL++ + + V L++ R   
Sbjct: 406 VFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQVR 465

Query: 121 GALPELEQE 129
              P++ QE
Sbjct: 466 QRSPDIFQE 474


>gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens]
          Length = 632

 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 4/90 (4%)

Query: 31  EVKLKKNANG-LGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
           ++ L++N  G LGF  V   +E   +  +    IK +  G PA  +G I  GDI+LAVNG
Sbjct: 542 DIVLRRNTAGSLGFCIVGGYEE---YNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNG 598

Query: 90  RSTEGLIFQEVLHLLRGAPQEVTLLLCRPP 119
           RST G+I   +  LL+     +TL +   P
Sbjct: 599 RSTSGMIHACLARLLKELKGRITLTIVSWP 628



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 18/69 (26%), Positives = 32/69 (46%)

Query: 61  VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
           V I  +  G  A  +G +   D +LA+NG        +   HL++ + + V L++ R   
Sbjct: 310 VFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQVR 369

Query: 121 GALPELEQE 129
              P++ QE
Sbjct: 370 QRSPDIFQE 378


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,000,567
Number of Sequences: 37866
Number of extensions: 597262
Number of successful extensions: 2054
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 1783
Number of HSP's gapped (non-prelim): 289
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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