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Search of human proteins with 63252916
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63252916 FERM and PDZ domain containing 2 isoform 2 [Homo
sapiens]
(261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa... 531 e-151
gi|110346440 FERM and PDZ domain containing 2 isoform 4 [Homo sa... 531 e-151
gi|63252916 FERM and PDZ domain containing 2 isoform 2 [Homo sap... 531 e-151
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa... 531 e-151
gi|110346445 FERM and PDZ domain containing 2 like 1 isoform 4 [... 530 e-151
gi|110346443 FERM and PDZ domain containing 2 like 1 isoform 2 [... 530 e-151
gi|110346449 FERM and PDZ domain containing 2 like 2 isoform 4 [... 530 e-151
gi|110346447 FERM and PDZ domain containing 2 like 2 isoform 2 [... 530 e-151
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 123 1e-28
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 123 1e-28
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 123 1e-28
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is... 123 1e-28
gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens] 54 1e-07
gi|4759306 lin-7 homolog A [Homo sapiens] 53 2e-07
gi|148833504 interleukin 16 isoform 2 [Homo sapiens] 52 4e-07
gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens] 52 4e-07
gi|8922944 lin-7 homolog C [Homo sapiens] 52 4e-07
gi|148612825 Rap GTPase interactor [Homo sapiens] 52 7e-07
gi|119120907 par-3 partitioning defective 3 homolog B isoform a ... 52 7e-07
gi|119120903 par-3 partitioning defective 3 homolog B isoform c ... 52 7e-07
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 51 9e-07
gi|11545920 lin-7 homolog B [Homo sapiens] 51 9e-07
gi|112382257 InaD-like [Homo sapiens] 50 3e-06
gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] 50 3e-06
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 50 3e-06
gi|155969695 membrane-associated guanylate kinase-related 3 iso... 50 3e-06
gi|148746189 multiple PDZ domain protein [Homo sapiens] 49 4e-06
gi|119120897 par-3 partitioning defective 3 homolog B isoform b ... 49 4e-06
gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens] 49 6e-06
gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens] 49 6e-06
>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
sapiens]
Length = 1287
Score = 531 bits (1368), Expect = e-151
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1027 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 1086
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 1087 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 1146
Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 1147 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 1206
Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 1207 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 1266
Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
IMRLGRYSFSSPLTRLSTDIF
Sbjct: 1267 IMRLGRYSFSSPLTRLSTDIF 1287
Score = 42.4 bits (98), Expect = 4e-04
Identities = 35/111 (31%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 14 LPGRPSSCV----SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPG 69
L G SSC ++ G + V+L K LGFS S + + +K + PG
Sbjct: 907 LKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPY---GGIYVKSIVPG 963
Query: 70 QPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
PA + G I GD +L V+G GL ++ + L G Q L+L R P
Sbjct: 964 GPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1014
Score = 41.6 bits (96), Expect = 7e-04
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
V LK++ + GF FV E E + I + PG PAE+ I G ILA+N S
Sbjct: 754 VTLKRDPHR-GFGFVINEGEYSGQADPGIF-ISSIIPGGPAEKAKTIKPGGQILALNHIS 811
Query: 92 TEGLIFQEVLHLLRGAPQEVTLLL 115
EG F + +++ +P + L++
Sbjct: 812 LEGFTFNMAVRMIQNSPDNIELII 835
>gi|110346440 FERM and PDZ domain containing 2 isoform 4 [Homo
sapiens]
Length = 320
Score = 531 bits (1368), Expect = e-151
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 60 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 119
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 120 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 179
Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 180 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 239
Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 240 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 299
Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
IMRLGRYSFSSPLTRLSTDIF
Sbjct: 300 IMRLGRYSFSSPLTRLSTDIF 320
>gi|63252916 FERM and PDZ domain containing 2 isoform 2 [Homo
sapiens]
Length = 261
Score = 531 bits (1368), Expect = e-151
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
IMRLGRYSFSSPLTRLSTDIF
Sbjct: 241 IMRLGRYSFSSPLTRLSTDIF 261
>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
sapiens]
Length = 1309
Score = 531 bits (1368), Expect = e-151
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1049 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 1108
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 1109 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 1168
Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 1169 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 1228
Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 1229 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 1288
Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
IMRLGRYSFSSPLTRLSTDIF
Sbjct: 1289 IMRLGRYSFSSPLTRLSTDIF 1309
Score = 42.4 bits (98), Expect = 4e-04
Identities = 35/111 (31%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 14 LPGRPSSCV----SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPG 69
L G SSC ++ G + V+L K LGFS S + + +K + PG
Sbjct: 929 LKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPY---GGIYVKSIVPG 985
Query: 70 QPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
PA + G I GD +L V+G GL ++ + L G Q L+L R P
Sbjct: 986 GPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1036
Score = 41.6 bits (96), Expect = 7e-04
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
V LK++ + GF FV E E + I + PG PAE+ I G ILA+N S
Sbjct: 776 VTLKRDPHR-GFGFVINEGEYSGQADPGIF-ISSIIPGGPAEKAKTIKPGGQILALNHIS 833
Query: 92 TEGLIFQEVLHLLRGAPQEVTLLL 115
EG F + +++ +P + L++
Sbjct: 834 LEGFTFNMAVRMIQNSPDNIELII 857
>gi|110346445 FERM and PDZ domain containing 2 like 1 isoform 4
[Homo sapiens]
Length = 320
Score = 530 bits (1366), Expect = e-151
Identities = 260/261 (99%), Positives = 261/261 (100%)
Query: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 60 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 119
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 120 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 179
Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
GALPE+EQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 180 GALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 239
Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 240 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 299
Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
IMRLGRYSFSSPLTRLSTDIF
Sbjct: 300 IMRLGRYSFSSPLTRLSTDIF 320
>gi|110346443 FERM and PDZ domain containing 2 like 1 isoform 2
[Homo sapiens]
Length = 261
Score = 530 bits (1366), Expect = e-151
Identities = 260/261 (99%), Positives = 261/261 (100%)
Query: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
GALPE+EQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 121 GALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
IMRLGRYSFSSPLTRLSTDIF
Sbjct: 241 IMRLGRYSFSSPLTRLSTDIF 261
>gi|110346449 FERM and PDZ domain containing 2 like 2 isoform 4
[Homo sapiens]
Length = 320
Score = 530 bits (1366), Expect = e-151
Identities = 260/261 (99%), Positives = 261/261 (100%)
Query: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 60 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 119
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 120 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 179
Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
GALPE+EQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 180 GALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 239
Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 240 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 299
Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
IMRLGRYSFSSPLTRLSTDIF
Sbjct: 300 IMRLGRYSFSSPLTRLSTDIF 320
>gi|110346447 FERM and PDZ domain containing 2 like 2 isoform 2
[Homo sapiens]
Length = 261
Score = 530 bits (1366), Expect = e-151
Identities = 260/261 (99%), Positives = 261/261 (100%)
Query: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL
Sbjct: 1 MGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDL 60
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP
Sbjct: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
Query: 121 GALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
GALPE+EQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS
Sbjct: 121 GALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESS 180
Query: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD
Sbjct: 181 QKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCD 240
Query: 241 IMRLGRYSFSSPLTRLSTDIF 261
IMRLGRYSFSSPLTRLSTDIF
Sbjct: 241 IMRLGRYSFSSPLTRLSTDIF 261
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 123 bits (309), Expect = 1e-28
Identities = 72/166 (43%), Positives = 97/166 (58%), Gaps = 17/166 (10%)
Query: 24 VTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDI 83
VT+ FEVKL KN++GLGFSF + + + + +VR+K+LFPGQPA E+G I GD+
Sbjct: 1499 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1558
Query: 84 ILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS------- 136
IL VNG S +GL QEV+ LRG EV LLLCRPPPG LPE++ TP S
Sbjct: 1559 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1618
Query: 137 ADKEFTRATCTDSCTSPILDQ----------EDSWRDSASPDAGEG 172
+ K+ ++ +C + TS ++ S RDS S +G G
Sbjct: 1619 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSG 1664
Score = 56.2 bits (134), Expect = 3e-08
Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 23 SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 77
S+ P+ E V LKK+A GLGF + EK + DL + I + PG PA+ +G
Sbjct: 1082 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1137
Query: 78 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 118
+ GD +++VN S EG+ + +L+ AP++VTL++ +P
Sbjct: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1178
Score = 53.1 bits (126), Expect = 2e-07
Identities = 36/91 (39%), Positives = 49/91 (53%), Gaps = 2/91 (2%)
Query: 27 GPKFEVKLKKNANGLGFSF-VQMEKESCS-HLKSDLVRIKRLFPGQPAEENGAIAAGDII 84
G FEV+L KN N LG S V +K + ++ + +K + P AE +G I GD +
Sbjct: 1364 GDIFEVELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRV 1423
Query: 85 LAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
LAVNG S EG ++ + LR Q V LLL
Sbjct: 1424 LAVNGVSLEGATHKQAVETLRNTGQVVHLLL 1454
Score = 32.7 bits (73), Expect = 0.33
Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)
Query: 31 EVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
++ L N LGFS C S +V I + P A G + D+I VN
Sbjct: 1888 DITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVN 1940
Query: 89 GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADK--EFTRATC 146
G ST+G+ +EV L + + L R +P ++ +SA K + +
Sbjct: 1941 GVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVSAPKSTKGNGSYS 1996
Query: 147 TDSCTSPILDQEDSWRDSASPDAGE 171
SC+ P L DS+ A + E
Sbjct: 1997 VGSCSQPALTPNDSFSTVAGEEINE 2021
Score = 31.2 bits (69), Expect = 0.95
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 71 PAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEW 130
PA+ +G + GD ++ VN + + ++LLR A + V L++ G + EL +
Sbjct: 1826 PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVI-----GRVLELPRIP 1880
Query: 131 QTPELSADKEFT 142
P L D T
Sbjct: 1881 MLPHLLPDITLT 1892
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 123 bits (309), Expect = 1e-28
Identities = 72/166 (43%), Positives = 97/166 (58%), Gaps = 17/166 (10%)
Query: 24 VTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDI 83
VT+ FEVKL KN++GLGFSF + + + + +VR+K+LFPGQPA E+G I GD+
Sbjct: 1303 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1362
Query: 84 ILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS------- 136
IL VNG S +GL QEV+ LRG EV LLLCRPPPG LPE++ TP S
Sbjct: 1363 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1422
Query: 137 ADKEFTRATCTDSCTSPILDQ----------EDSWRDSASPDAGEG 172
+ K+ ++ +C + TS ++ S RDS S +G G
Sbjct: 1423 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSG 1468
Score = 56.2 bits (134), Expect = 3e-08
Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 23 SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 77
S+ P+ E V LKK+A GLGF + EK + DL + I + PG PA+ +G
Sbjct: 891 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 946
Query: 78 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 118
+ GD +++VN S EG+ + +L+ AP++VTL++ +P
Sbjct: 947 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 987
Score = 54.7 bits (130), Expect = 8e-08
Identities = 36/89 (40%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 27 GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
G FEV+L KN N LG S S H + +K + P AE +G I GD +LA
Sbjct: 1173 GDIFEVELAKNDNSLGISVTGGVNTSVRH---GGIYVKAVIPQGAAESDGRIHKGDRVLA 1229
Query: 87 VNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
VNG S EG ++ + LR Q V LLL
Sbjct: 1230 VNGVSLEGATHKQAVETLRNTGQVVHLLL 1258
Score = 32.7 bits (73), Expect = 0.33
Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)
Query: 31 EVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
++ L N LGFS C S +V I + P A G + D+I VN
Sbjct: 1692 DITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVN 1744
Query: 89 GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADK--EFTRATC 146
G ST+G+ +EV L + + L R +P ++ +SA K + +
Sbjct: 1745 GVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVSAPKSTKGNGSYS 1800
Query: 147 TDSCTSPILDQEDSWRDSASPDAGE 171
SC+ P L DS+ A + E
Sbjct: 1801 VGSCSQPALTPNDSFSTVAGEEINE 1825
Score = 31.2 bits (69), Expect = 0.95
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 71 PAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEW 130
PA+ +G + GD ++ VN + + ++LLR A + V L++ G + EL +
Sbjct: 1630 PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVI-----GRVLELPRIP 1684
Query: 131 QTPELSADKEFT 142
P L D T
Sbjct: 1685 MLPHLLPDITLT 1696
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 123 bits (309), Expect = 1e-28
Identities = 72/166 (43%), Positives = 97/166 (58%), Gaps = 17/166 (10%)
Query: 24 VTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDI 83
VT+ FEVKL KN++GLGFSF + + + + +VR+K+LFPGQPA E+G I GD+
Sbjct: 1494 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1553
Query: 84 ILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS------- 136
IL VNG S +GL QEV+ LRG EV LLLCRPPPG LPE++ TP S
Sbjct: 1554 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1613
Query: 137 ADKEFTRATCTDSCTSPILDQ----------EDSWRDSASPDAGEG 172
+ K+ ++ +C + TS ++ S RDS S +G G
Sbjct: 1614 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSG 1659
Score = 56.2 bits (134), Expect = 3e-08
Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 23 SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 77
S+ P+ E V LKK+A GLGF + EK + DL + I + PG PA+ +G
Sbjct: 1082 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1137
Query: 78 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 118
+ GD +++VN S EG+ + +L+ AP++VTL++ +P
Sbjct: 1138 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1178
Score = 54.7 bits (130), Expect = 8e-08
Identities = 36/89 (40%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 27 GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
G FEV+L KN N LG S S H + +K + P AE +G I GD +LA
Sbjct: 1364 GDIFEVELAKNDNSLGISVTGGVNTSVRH---GGIYVKAVIPQGAAESDGRIHKGDRVLA 1420
Query: 87 VNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
VNG S EG ++ + LR Q V LLL
Sbjct: 1421 VNGVSLEGATHKQAVETLRNTGQVVHLLL 1449
Score = 32.7 bits (73), Expect = 0.33
Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)
Query: 31 EVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
++ L N LGFS C S +V I + P A G + D+I VN
Sbjct: 1883 DITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVN 1935
Query: 89 GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADK--EFTRATC 146
G ST+G+ +EV L + + L R +P ++ +SA K + +
Sbjct: 1936 GVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVSAPKSTKGNGSYS 1991
Query: 147 TDSCTSPILDQEDSWRDSASPDAGE 171
SC+ P L DS+ A + E
Sbjct: 1992 VGSCSQPALTPNDSFSTVAGEEINE 2016
Score = 31.2 bits (69), Expect = 0.95
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 71 PAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEW 130
PA+ +G + GD ++ VN + + ++LLR A + V L++ G + EL +
Sbjct: 1821 PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVI-----GRVLELPRIP 1875
Query: 131 QTPELSADKEFT 142
P L D T
Sbjct: 1876 MLPHLLPDITLT 1887
>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
2 [Homo sapiens]
Length = 2466
Score = 123 bits (309), Expect = 1e-28
Identities = 72/166 (43%), Positives = 97/166 (58%), Gaps = 17/166 (10%)
Query: 24 VTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDI 83
VT+ FEVKL KN++GLGFSF + + + + +VR+K+LFPGQPA E+G I GD+
Sbjct: 1475 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1534
Query: 84 ILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS------- 136
IL VNG S +GL QEV+ LRG EV LLLCRPPPG LPE++ TP S
Sbjct: 1535 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1594
Query: 137 ADKEFTRATCTDSCTSPILDQ----------EDSWRDSASPDAGEG 172
+ K+ ++ +C + TS ++ S RDS S +G G
Sbjct: 1595 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSG 1640
Score = 56.2 bits (134), Expect = 3e-08
Identities = 36/101 (35%), Positives = 58/101 (57%), Gaps = 9/101 (8%)
Query: 23 SVTDGPKFE---VKLKKNAN-GLGFSFVQMEKESCSHLKSDL-VRIKRLFPGQPAEENGA 77
S+ P+ E V LKK+A GLGF + EK + DL + I + PG PA+ +G
Sbjct: 1063 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMG----RLDLGIFISSVAPGGPADLDGC 1118
Query: 78 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRP 118
+ GD +++VN S EG+ + +L+ AP++VTL++ +P
Sbjct: 1119 LKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQP 1159
Score = 54.7 bits (130), Expect = 8e-08
Identities = 36/89 (40%), Positives = 45/89 (50%), Gaps = 3/89 (3%)
Query: 27 GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
G FEV+L KN N LG S S H + +K + P AE +G I GD +LA
Sbjct: 1345 GDIFEVELAKNDNSLGISVTGGVNTSVRH---GGIYVKAVIPQGAAESDGRIHKGDRVLA 1401
Query: 87 VNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
VNG S EG ++ + LR Q V LLL
Sbjct: 1402 VNGVSLEGATHKQAVETLRNTGQVVHLLL 1430
Score = 32.7 bits (73), Expect = 0.33
Identities = 38/145 (26%), Positives = 58/145 (40%), Gaps = 15/145 (10%)
Query: 31 EVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
++ L N LGFS C S +V I + P A G + D+I VN
Sbjct: 1864 DITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVN 1916
Query: 89 GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADK--EFTRATC 146
G ST+G+ +EV L + + L R +P ++ +SA K + +
Sbjct: 1917 GVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVSAPKSTKGNGSYS 1972
Query: 147 TDSCTSPILDQEDSWRDSASPDAGE 171
SC+ P L DS+ A + E
Sbjct: 1973 VGSCSQPALTPNDSFSTVAGEEINE 1997
Score = 31.2 bits (69), Expect = 0.95
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 71 PAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEW 130
PA+ +G + GD ++ VN + + ++LLR A + V L++ G + EL +
Sbjct: 1802 PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVI-----GRVLELPRIP 1856
Query: 131 QTPELSADKEFT 142
P L D T
Sbjct: 1857 MLPHLLPDITLT 1868
>gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]
Length = 1434
Score = 53.9 bits (128), Expect = 1e-07
Identities = 40/97 (41%), Positives = 50/97 (51%), Gaps = 14/97 (14%)
Query: 35 KKNANGLGFSFVQMEKESCSH---LKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
K+ GLGF + KE S + SDL+R G AE++G I AGDIILAVNGR
Sbjct: 22 KRKVGGLGF----LVKERVSKPPVIISDLIR------GGAAEQSGLIQAGDIILAVNGRP 71
Query: 92 TEGLIFQEVLHLLRGAPQEV-TLLLCRPPPGALPELE 127
L + L +LRG E +L+ R P G LE
Sbjct: 72 LVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLE 108
>gi|4759306 lin-7 homolog A [Homo sapiens]
Length = 233
Score = 53.1 bits (126), Expect = 2e-07
Identities = 33/100 (33%), Positives = 55/100 (55%), Gaps = 7/100 (7%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
V+L K GLGF+ + ++++ + I R+ PG AE +G + GD +L+VNG S
Sbjct: 109 VELPKTDEGLGFNVMGGKEQNSP------IYISRIIPGGVAERHGGLKRGDQLLSVNGVS 162
Query: 92 TEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQ 131
EG ++ + LL+ A V L++ R P L E+E ++
Sbjct: 163 VEGEHHEKAVELLKAAKDSVKLVV-RYTPKVLEEMEARFE 201
>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
Length = 1332
Score = 52.4 bits (124), Expect = 4e-07
Identities = 30/103 (29%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Query: 26 DGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIIL 85
DG + K+ GLGFS + L++ ++ + R+FP A + G I G+ +L
Sbjct: 1109 DGIHVTILHKEEGAGLGFSLA-----GGADLENKVITVHRVFPNGLASQEGTIQKGNEVL 1163
Query: 86 AVNGRSTEGLIFQEVLHLLRGA--PQEVTLLLCRPPPGALPEL 126
++NG+S +G + L +LR A P++ ++ + P A+P+L
Sbjct: 1164 SINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDL 1206
Score = 50.8 bits (120), Expect = 1e-06
Identities = 53/184 (28%), Positives = 81/184 (44%), Gaps = 14/184 (7%)
Query: 2 GDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLV 61
G R SL TA +PS + + V +K A GLGFS V + + +
Sbjct: 189 GTSRPTRSLSTAQLVQPSGGLQASVISNI-VLMKGQAKGLGFSIVGGKDSIYGPIG---I 244
Query: 62 RIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPG 121
+K +F G A +G + GD IL +NG S GL Q+ L + A + + L R
Sbjct: 245 YVKTIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKGLLTLTVRTRLT 304
Query: 122 ALPELEQEWQTP---ELSADKEFTRATCT---DSCTSPILDQEDSWR----DSASPDAGE 171
A P L P LS+ T+ + + +S ++PI + ++R S +AG
Sbjct: 305 APPSLCSHLSPPLCRSLSSSTCITKDSSSFALESPSAPISTAKPNYRIMVEVSLQKEAGV 364
Query: 172 GLGL 175
GLG+
Sbjct: 365 GLGI 368
Score = 39.3 bits (90), Expect = 0.003
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 9 SLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFP 68
S +A S S + V L+K + GLGFS +E S + I R+F
Sbjct: 1212 SAASASAASDVSVESTAEATVCTVTLEKMSAGLGFS---LEGGKGSLHGDKPLTINRIFK 1268
Query: 69 GQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQ-EVTLLLCR 117
G +E++ + GD IL + G + +GL E ++++ P VT+++ R
Sbjct: 1269 GAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRR 1318
Score = 30.4 bits (67), Expect = 1.6
Identities = 44/197 (22%), Positives = 72/197 (36%), Gaps = 12/197 (6%)
Query: 15 PGRPSSCVSVTDGPKFEVKLKKNAN-GLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAE 73
P P S EV L+K A GLG + C + + L PG A
Sbjct: 339 PSAPISTAKPNYRIMVEVSLQKEAGVGLGIGLCSVPYFQCI----SGIFVHTLSPGSVAH 394
Query: 74 ENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGA-PQEVTLLLCRPPPGALPELEQEWQT 132
+G + GD I+ ++ L EV +L P V +++ R P + E + +
Sbjct: 395 LDGRLRCGDEIVEISDSPVHCLTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLKEAV 454
Query: 133 PELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQN 192
+ + +F + S + E SW + + R ++S R AQ
Sbjct: 455 AQAVENTKFGKERHQWSLEG-VKRLESSWHGRPTLEKE-----REKNSAPPHRRAQKVMI 508
Query: 193 RERPWASSLTHSPESHP 209
R +S ++ SP P
Sbjct: 509 RSSSDSSYMSGSPGGSP 525
>gi|27262655 interleukin 16 isoform 1 precursor [Homo sapiens]
Length = 631
Score = 52.4 bits (124), Expect = 4e-07
Identities = 30/103 (29%), Positives = 55/103 (53%), Gaps = 7/103 (6%)
Query: 26 DGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIIL 85
DG + K+ GLGFS + L++ ++ + R+FP A + G I G+ +L
Sbjct: 408 DGIHVTILHKEEGAGLGFSLA-----GGADLENKVITVHRVFPNGLASQEGTIQKGNEVL 462
Query: 86 AVNGRSTEGLIFQEVLHLLRGA--PQEVTLLLCRPPPGALPEL 126
++NG+S +G + L +LR A P++ ++ + P A+P+L
Sbjct: 463 SINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDL 505
Score = 39.3 bits (90), Expect = 0.003
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 9 SLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFP 68
S +A S S + V L+K + GLGFS +E S + I R+F
Sbjct: 511 SAASASAASDVSVESTAEATVCTVTLEKMSAGLGFS---LEGGKGSLHGDKPLTINRIFK 567
Query: 69 GQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQ-EVTLLLCR 117
G +E++ + GD IL + G + +GL E ++++ P VT+++ R
Sbjct: 568 GAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRR 617
>gi|8922944 lin-7 homolog C [Homo sapiens]
Length = 197
Score = 52.4 bits (124), Expect = 4e-07
Identities = 32/100 (32%), Positives = 56/100 (56%), Gaps = 7/100 (7%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
V+L K GLGF+ + ++++ + I R+ PG A+ +G + GD +L+VNG S
Sbjct: 94 VELPKTEEGLGFNIMGGKEQNSP------IYISRIIPGGIADRHGGLKRGDQLLSVNGVS 147
Query: 92 TEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQ 131
EG ++ + LL+ A +V L++ R P L E+E ++
Sbjct: 148 VEGEHHEKAVELLKAAQGKVKLVV-RYTPKVLEEMESRFE 186
>gi|148612825 Rap GTPase interactor [Homo sapiens]
Length = 1075
Score = 51.6 bits (122), Expect = 7e-07
Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 5/116 (4%)
Query: 4 ERTAVSLVTALPGRPSSCVSVTDG--PKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLV 61
E + +L P PSS S T+ F V+L++ +GLG + +HL + +
Sbjct: 947 EGDSAALAEESPPAPSSRSSSTEDFCYVFTVELERGPSGLGMGLIDGMH---THLGAPGL 1003
Query: 62 RIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
I+ L PG PA +G ++ GD IL VNG S GL + + L+R +++ L+ +
Sbjct: 1004 YIQTLLPGSPAAADGRLSLGDRILEVNGSSLLGLGYLRAVDLIRHGGKKMRFLVAK 1059
>gi|119120907 par-3 partitioning defective 3 homolog B isoform a
[Homo sapiens]
Length = 1104
Score = 51.6 bits (122), Expect = 7e-07
Identities = 57/183 (31%), Positives = 83/183 (45%), Gaps = 28/183 (15%)
Query: 11 VTALPGRPSSCV--------SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVR 62
V L G+PSS S + K ++ LKK GLGF+ V ++S H +
Sbjct: 355 VPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVT--RDSSIHGPGPIF- 411
Query: 63 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVT--LLLCRPPP 120
+K + P A ++G + +GD IL VNGR G +E++ +LR Q T L++ R
Sbjct: 412 VKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEG 471
Query: 121 GALP-ELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPES 179
LP EL+ E LS + TS L E DS S AG G+ L+
Sbjct: 472 HFLPRELKGEPDCCALSLE------------TSEQLTFEIPLNDSGS--AGLGVSLKGNK 517
Query: 180 SQK 182
S++
Sbjct: 518 SRE 520
>gi|119120903 par-3 partitioning defective 3 homolog B isoform c
[Homo sapiens]
Length = 1136
Score = 51.6 bits (122), Expect = 7e-07
Identities = 57/183 (31%), Positives = 83/183 (45%), Gaps = 28/183 (15%)
Query: 11 VTALPGRPSSCV--------SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVR 62
V L G+PSS S + K ++ LKK GLGF+ V ++S H +
Sbjct: 355 VPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVT--RDSSIHGPGPIF- 411
Query: 63 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVT--LLLCRPPP 120
+K + P A ++G + +GD IL VNGR G +E++ +LR Q T L++ R
Sbjct: 412 VKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEG 471
Query: 121 GALP-ELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPES 179
LP EL+ E LS + TS L E DS S AG G+ L+
Sbjct: 472 HFLPRELKGEPDCCALSLE------------TSEQLTFEIPLNDSGS--AGLGVSLKGNK 517
Query: 180 SQK 182
S++
Sbjct: 518 SRE 520
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 51.2 bits (121), Expect = 9e-07
Identities = 36/110 (32%), Positives = 52/110 (47%), Gaps = 9/110 (8%)
Query: 30 FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
F V ++K A G GFS K DL + RL PA NG + GD I+ +NG
Sbjct: 1146 FTVDMEKGAKGFGFSI-----RGGREYKMDLY-VLRLAEDGPAIRNGRMRVGDQIIEING 1199
Query: 90 RSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQ--EWQTPELSA 137
ST + + L++ + V LLL R G +PE ++ W +P +A
Sbjct: 1200 ESTRDMTHARAIELIKSGGRRVRLLLKR-GTGQVPEYDEPAPWSSPAAAA 1248
Score = 39.3 bits (90), Expect = 0.003
Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 10/102 (9%)
Query: 42 GFSFVQMEKESCSHLKSDLV---RIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQ 98
GF FV + + S + +I R+ G PA+ + GD ILAVNG+S +
Sbjct: 930 GFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHA 989
Query: 99 EVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADKE 140
+++ L++ A VTL + +P+ E T S++K+
Sbjct: 990 DIVKLIKDAGLSVTLRI-------IPQEELNSPTSAPSSEKQ 1024
>gi|11545920 lin-7 homolog B [Homo sapiens]
Length = 207
Score = 51.2 bits (121), Expect = 9e-07
Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 7/100 (7%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
V+L K GLGF+ + ++++ + I R+ PG A+ +G + GD +L+VNG S
Sbjct: 94 VELPKTDEGLGFNIMGGKEQNSP------IYISRVIPGGVADRHGGLKRGDQLLSVNGVS 147
Query: 92 TEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQ 131
EG ++ + LL+ A V L++ R P L E+E ++
Sbjct: 148 VEGEQHEKAVELLKAAQGSVKLVV-RYTPRVLEEMEARFE 186
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 49.7 bits (117), Expect = 3e-06
Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 8/91 (8%)
Query: 31 EVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGR 90
EV+L + +GLGF V K+ V ++ + PG A+ +G + GD IL + G
Sbjct: 248 EVELINDGSGLGFGIVGG--------KTSGVVVRTIVPGGLADRDGRLQTGDHILKIGGT 299
Query: 91 STEGLIFQEVLHLLRGAPQEVTLLLCRPPPG 121
+ +G+ ++V +LR V +L+ R P G
Sbjct: 300 NVQGMTSEQVAQVLRNCGNSVRMLVARDPAG 330
Score = 43.9 bits (102), Expect = 1e-04
Identities = 35/110 (31%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 8 VSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLF 67
V+L T P S S+ + E+ ++K+ LG V S + S + +K +
Sbjct: 344 VALPTVASKGPGSDSSLFETYNVEL-VRKDGQSLGIRIVGYVGTSHTGEASGIY-VKSII 401
Query: 68 PGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
PG A NG I D I+AV+G + +G +V+ +LR A Q V L L R
Sbjct: 402 PGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVVEVLRNAGQVVHLTLVR 451
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 18 PSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGA 77
P++C + G + +++ K +GLG S V + + + I ++ A +G
Sbjct: 1425 PATC-PIVPGQEMIIEISKGRSGLGLSIVGGKDTPLN-----AIVIHEVYEEGAAARDGR 1478
Query: 78 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
+ AGD IL VNG +E + LR PQ+V L++ R
Sbjct: 1479 LWAGDQILEVNGVDLRNSSHEEAITALRQTPQKVRLVVYR 1518
Score = 37.7 bits (86), Expect = 0.010
Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 3/133 (2%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
V+L K+ GLGFS + + + +S +V I+ L AE +G + GD +++VN
Sbjct: 687 VELVKDCKGLGFSILDYQ-DPLDPTRSVIV-IRSLVADGVAERSGGLLPGDRLVSVNEYC 744
Query: 92 TEGLIFQEVLHLLRGAPQE-VTLLLCRPPPGALPELEQEWQTPELSADKEFTRATCTDSC 150
+ E + +L+ P V L +C+P E + DK T D
Sbjct: 745 LDNTSLAEAVEILKAVPPGLVHLGICKPLVEDNEEESCYILHSSSNEDKTEFSGTIHDIN 804
Query: 151 TSPILDQEDSWRD 163
+S IL+ +RD
Sbjct: 805 SSLILEAPKGFRD 817
Score = 37.0 bits (84), Expect = 0.017
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 19/123 (15%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
++L+K+ NGLG S + S + + + P PA +G + GD +L +N +
Sbjct: 1240 IELEKDKNGLGLSLAGNKDRSRMS-----IFVVGINPEGPAAADGRMRIGDELLEINNQI 1294
Query: 92 TEGLIFQEVLHLLRGAPQEVTLLLCR-------------PPPGALP-ELEQEWQTPELSA 137
G Q +++ AP +V L+ R P P + P +E + T +S+
Sbjct: 1295 LYGRSHQNASAIIKTAPSKVKLVFIRNEDAVNQMAVTPFPVPSSSPSSIEDQSGTEPISS 1354
Query: 138 DKE 140
+++
Sbjct: 1355 EED 1357
Score = 33.5 bits (75), Expect = 0.19
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 35 KKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS-TE 93
+ + GLGFS V + ++ + + +K + PG A+ + + D ILA+N +
Sbjct: 139 RPSTGGLGFSVVALRSQNLGKVD---IFVKDVQPGSVADRDQRLKENDQILAINHTPLDQ 195
Query: 94 GLIFQEVLHLLRGAPQEVTLLLCRPP 119
+ Q+ + LL+ + L++ R P
Sbjct: 196 NISHQQAIALLQQTTGSLRLIVAREP 221
Score = 32.0 bits (71), Expect = 0.56
Identities = 17/55 (30%), Positives = 25/55 (45%)
Query: 63 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
I + G P + G + D +L VNG G +E + L+ P TL+ CR
Sbjct: 583 ISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLVCCR 637
Score = 32.0 bits (71), Expect = 0.56
Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 8/94 (8%)
Query: 30 FEVKLKKNAN-GLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVN 88
F V L+K A GLG S V S + SD+V+ G A+ +G + GD IL+VN
Sbjct: 1532 FPVDLQKKAGRGLGLSIVGKRNGSGVFI-SDIVK------GGAADLDGRLIQGDQILSVN 1584
Query: 89 GRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGA 122
G + V +L+ A V L + R G+
Sbjct: 1585 GEDMRNASQETVATILKCAQGLVQLEIGRLRAGS 1618
Score = 28.5 bits (62), Expect = 6.2
Identities = 14/53 (26%), Positives = 25/53 (47%)
Query: 63 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
IK++ PA + A+ GD IL V+G + E + ++ A V ++
Sbjct: 1104 IKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASHSEAVEAIKNAGNPVVFIV 1156
Score = 28.1 bits (61), Expect = 8.1
Identities = 12/36 (33%), Positives = 23/36 (63%)
Query: 78 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTL 113
+ GD I+++NG+ +GL +V++LL+ A + L
Sbjct: 1721 LKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIIL 1756
>gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens]
Length = 1356
Score = 49.7 bits (117), Expect = 3e-06
Identities = 47/167 (28%), Positives = 75/167 (44%), Gaps = 8/167 (4%)
Query: 27 GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
G + ++LKK GLGFS + S + +K + P A ++G + AGD ++
Sbjct: 457 GKRLNIQLKKGTEGLGFSITSRDVTIGG---SAPIYVKNILPRGAAIQDGRLKAGDRLIE 513
Query: 87 VNGRSTEGLIFQEVLHLLRGAPQE--VTLLLCRPPPGALPELEQEWQTPELSADKEFTRA 144
VNG G +EV+ LLR E V+LL+ R P E + ++ KE T+A
Sbjct: 514 VNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPR-ELNAEPSQMQIPKE-TKA 571
Query: 145 TCTDSCTSPILDQEDSWRDSASPDAGE-GLGLRPESSQKAIREAQWG 190
D +P +E + D+G GLG+ + ++ A G
Sbjct: 572 EDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLG 618
>gi|218505835 membrane-associated guanylate kinase-related 3
isoform 1 [Homo sapiens]
Length = 1481
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/179 (24%), Positives = 81/179 (45%), Gaps = 23/179 (12%)
Query: 27 GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
G LKK+ G GF+ + ++ + +++K + PA ++G IA GD+I+
Sbjct: 406 GVLVRASLKKSTMGFGFTIIGGDRPD------EFLQVKNVLKDGPAAQDGKIAPGDVIVD 459
Query: 87 VNGRSTEGLIFQEVLHLLRGAP--QEVTLLLCRPPPGALPELEQEWQTPELSADKEFTRA 144
+NG G +V+ + + P Q V L LCR P LP+ ++ ++A
Sbjct: 460 INGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYP--LPDDSEDPVVDIVAATPVINGQ 517
Query: 145 TCT--DSCTSP--------ILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQNR 193
+ T ++C +P +L+Q S G+GL ++S++ + A G ++
Sbjct: 518 SLTKGETCMNPQDFKPGAMVLEQNGK---SGHTLTGDGLNGPSDASEQRVSMASSGSSQ 573
Score = 45.1 bits (105), Expect = 6e-05
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 7/96 (7%)
Query: 30 FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
+ V+L++ G GFS ++ + + I RL PA ++G I GD I+ +NG
Sbjct: 1020 YPVELERGPRGFGFSLRGGKEYNMG------LFILRLAEDGPAIKDGRIHVGDQIVEING 1073
Query: 90 RSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPE 125
T+G+ + L++ +V LLL RP G +P+
Sbjct: 1074 EPTQGITHTRAIELIQAGGNKV-LLLLRPGTGLIPD 1108
Score = 39.7 bits (91), Expect = 0.003
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 30 FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
++V L++ N GF FV + ++ +I R+ G PA+ G + GD I AVNG
Sbjct: 850 YDVVLQRKENE-GFGFVILTSKNKPPPGVIPHKIGRVIEGSPADRCGKLKVGDHISAVNG 908
Query: 90 RSTEGLIFQEVLHLLRGAPQEVTL 113
+S L ++ L++ A VTL
Sbjct: 909 QSIVELSHDNIVQLIKDAGVTVTL 932
>gi|155969695 membrane-associated guanylate kinase-related 3
isoform 2 [Homo sapiens]
Length = 1125
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/179 (24%), Positives = 81/179 (45%), Gaps = 23/179 (12%)
Query: 27 GPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILA 86
G LKK+ G GF+ + ++ + +++K + PA ++G IA GD+I+
Sbjct: 406 GVLVRASLKKSTMGFGFTIIGGDRPD------EFLQVKNVLKDGPAAQDGKIAPGDVIVD 459
Query: 87 VNGRSTEGLIFQEVLHLLRGAP--QEVTLLLCRPPPGALPELEQEWQTPELSADKEFTRA 144
+NG G +V+ + + P Q V L LCR P LP+ ++ ++A
Sbjct: 460 INGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYP--LPDDSEDPVVDIVAATPVINGQ 517
Query: 145 TCT--DSCTSP--------ILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQNR 193
+ T ++C +P +L+Q S G+GL ++S++ + A G ++
Sbjct: 518 SLTKGETCMNPQDFKPGAMVLEQNGK---SGHTLTGDGLNGPSDASEQRVSMASSGSSQ 573
Score = 45.1 bits (105), Expect = 6e-05
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 7/96 (7%)
Query: 30 FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
+ V+L++ G GFS ++ + + I RL PA ++G I GD I+ +NG
Sbjct: 1020 YPVELERGPRGFGFSLRGGKEYNMG------LFILRLAEDGPAIKDGRIHVGDQIVEING 1073
Query: 90 RSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPE 125
T+G+ + L++ +V LLL RP G +P+
Sbjct: 1074 EPTQGITHTRAIELIQAGGNKV-LLLLRPGTGLIPD 1108
Score = 39.7 bits (91), Expect = 0.003
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 30 FEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
++V L++ N GF FV + ++ +I R+ G PA+ G + GD I AVNG
Sbjct: 850 YDVVLQRKENE-GFGFVILTSKNKPPPGVIPHKIGRVIEGSPADRCGKLKVGDHISAVNG 908
Query: 90 RSTEGLIFQEVLHLLRGAPQEVTL 113
+S L ++ L++ A VTL
Sbjct: 909 QSIVELSHDNIVQLIKDAGVTVTL 932
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 48.9 bits (115), Expect = 4e-06
Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 18 PSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGA 77
P C S+T L++ +GLGFS V L + +K +F A E+G
Sbjct: 1953 PPQCKSIT--------LERGPDGLGFSIVGGYGSPHGDLP---IYVKTVFAKGAASEDGR 2001
Query: 78 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL 115
+ GD I+AVNG+S EG+ +E + +L+ VTL++
Sbjct: 2002 LKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMV 2039
Score = 46.2 bits (108), Expect = 3e-05
Identities = 36/125 (28%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 3 DERTA-VSLVTALPGRPSSCVSVT---------DGPKFEVKLKKNANGLGFSFVQMEKES 52
+ERTA +L L P+S + + F+V+L KN GLG + +
Sbjct: 339 EERTAPTALGITLSSSPTSTPELRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDK 398
Query: 53 CSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVT 112
L+ + +K + E +G I GD I+AV+G + +G Q+ + +LR Q V
Sbjct: 399 --KLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVL 456
Query: 113 LLLCR 117
L L R
Sbjct: 457 LTLMR 461
Score = 46.2 bits (108), Expect = 3e-05
Identities = 28/90 (31%), Positives = 50/90 (55%), Gaps = 3/90 (3%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
++L+K + GLGFS ++ + S ++ I+ L PG AE++G + GD ++ VN +
Sbjct: 701 IELEKGSKGLGFSI--LDYQDPIDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVN 758
Query: 92 TEGLIFQEVLHLLRGAPQ-EVTLLLCRPPP 120
E +E + L+GAP V + + +P P
Sbjct: 759 LENSSLEEAVEALKGAPSGTVRIGVAKPLP 788
Score = 43.9 bits (102), Expect = 1e-04
Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 7/94 (7%)
Query: 34 LKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTE 93
LK + GLGFS V + E+ L + ++ + G A +G + D ILA+NG++ +
Sbjct: 141 LKPPSGGLGFSVVGLRSENRGELG---IFVQEIQEGSVAHRDGRLKETDQILAINGQALD 197
Query: 94 GLI-FQEVLHLLRGAPQEVTLLLCRPPPGALPEL 126
I Q+ + +L+ A V L++ R G+LP+L
Sbjct: 198 QTITHQQAISILQKAKDTVQLVIAR---GSLPQL 228
Score = 43.5 bits (101), Expect = 2e-04
Identities = 24/67 (35%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Query: 63 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR--PPP 120
I+ + P P +G + +GD +L VNG + G Q+V+++L+ P EVT++ CR PP
Sbjct: 578 IRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPP 637
Query: 121 GALPELE 127
EL+
Sbjct: 638 TTQSELD 644
Score = 41.6 bits (96), Expect = 7e-04
Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 11/94 (11%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
++L + +GLGF + K+ V +K + PG A+++G + +GD IL +
Sbjct: 258 IELVNDGSGLGFGIIGG--------KATGVIVKTILPGGVADQHGRLCSGDHILKIGDTD 309
Query: 92 TEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPE 125
G+ ++V +LR V L++ R GA+ E
Sbjct: 310 LAGMSSEQVAQVLRQCGNRVKLMIAR---GAIEE 340
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 6/100 (6%)
Query: 18 PSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGA 77
P++C + G + +++ K GLG S V S + I ++ A ++G
Sbjct: 1617 PATC-PIIPGCETTIEISKGRTGLGLSIV-----GGSDTLLGAIIIHEVYEEGAACKDGR 1670
Query: 78 IAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCR 117
+ AGD IL VNG E +++LR PQ V L L R
Sbjct: 1671 LWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYR 1710
Score = 32.7 bits (73), Expect = 0.33
Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
++L+K +GLG S + S V I + P A ++G + D +L +NG+
Sbjct: 1351 IELEKGHSGLGLSLAGNKDRSRMS-----VFIVGIDPNGAAGKDGRLQIADELLEINGQI 1405
Query: 92 TEGLIFQEVLHLLRGAPQEVTLLLCR 117
G Q +++ AP +V ++ R
Sbjct: 1406 LYGRSHQNASSIIKCAPSKVKIIFIR 1431
Score = 31.6 bits (70), Expect = 0.73
Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 63 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTL----LLCRP 118
IK + PA +NG + GD I+ V+G ++ + +R A V ++ RP
Sbjct: 1187 IKHVLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRP 1246
Query: 119 PPGALPEL 126
LP L
Sbjct: 1247 RKSPLPSL 1254
Score = 30.4 bits (67), Expect = 1.6
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 35 KKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEG 94
KK GLG S V ++ + SD+V+ G A+ +G + GD IL VNG
Sbjct: 1730 KKPGKGLGLSIVGKRNDTGVFV-SDIVK------GGIADADGRLMQGDQILMVNGEDVRN 1782
Query: 95 LIFQEVLHLLR 105
+ V LL+
Sbjct: 1783 ATQEAVAALLK 1793
Score = 29.3 bits (64), Expect = 3.6
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 7/84 (8%)
Query: 32 VKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRS 91
++L K+ GLG + E+++ S V IK L A +G + GD ILAV+
Sbjct: 1484 LELPKDQGGLGIAI--SEEDTLSG-----VIIKSLTEHGVAATDGRLKVGDQILAVDDEI 1536
Query: 92 TEGLIFQEVLHLLRGAPQEVTLLL 115
G ++ + LL+ A V L +
Sbjct: 1537 VVGYPIEKFISLLKTAKMTVKLTI 1560
Score = 29.3 bits (64), Expect = 3.6
Identities = 14/51 (27%), Positives = 26/51 (50%)
Query: 63 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTL 113
I + P A + + GD I+ + G STEG+ + ++LL+ A + +
Sbjct: 1863 IAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEM 1913
>gi|119120897 par-3 partitioning defective 3 homolog B isoform b
[Homo sapiens]
Length = 1143
Score = 48.9 bits (115), Expect = 4e-06
Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 13/124 (10%)
Query: 11 VTALPGRPSSCV--------SVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVR 62
V L G+PSS S + K ++ LKK GLGF+ V ++S H +
Sbjct: 355 VPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVT--RDSSIHGPGPIF- 411
Query: 63 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVT--LLLCRPPP 120
+K + P A ++G + +GD IL VNGR G +E++ +LR Q T L++ R
Sbjct: 412 VKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEG 471
Query: 121 GALP 124
LP
Sbjct: 472 HFLP 475
>gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens]
Length = 728
Score = 48.5 bits (114), Expect = 6e-06
Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 31 EVKLKKNANG-LGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
++ L++N G LGF V +E + + IK + G PA +G I GDI+LAVNG
Sbjct: 638 DIVLRRNTAGSLGFCIVGGYEE---YNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNG 694
Query: 90 RSTEGLIFQEVLHLLRGAPQEVTLLLCRPP 119
RST G+I + LL+ +TL + P
Sbjct: 695 RSTSGMIHACLARLLKELKGRITLTIVSWP 724
Score = 29.3 bits (64), Expect = 3.6
Identities = 18/69 (26%), Positives = 32/69 (46%)
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
V I + G A +G + D +LA+NG + HL++ + + V L++ R
Sbjct: 406 VFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQVR 465
Query: 121 GALPELEQE 129
P++ QE
Sbjct: 466 QRSPDIFQE 474
>gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens]
Length = 632
Score = 48.5 bits (114), Expect = 6e-06
Identities = 33/90 (36%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 31 EVKLKKNANG-LGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNG 89
++ L++N G LGF V +E + + IK + G PA +G I GDI+LAVNG
Sbjct: 542 DIVLRRNTAGSLGFCIVGGYEE---YNGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNG 598
Query: 90 RSTEGLIFQEVLHLLRGAPQEVTLLLCRPP 119
RST G+I + LL+ +TL + P
Sbjct: 599 RSTSGMIHACLARLLKELKGRITLTIVSWP 628
Score = 29.3 bits (64), Expect = 3.6
Identities = 18/69 (26%), Positives = 32/69 (46%)
Query: 61 VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPP 120
V I + G A +G + D +LA+NG + HL++ + + V L++ R
Sbjct: 310 VFIFNVLDGGVAYRHGQLEENDRVLAINGHDLRYGSPESAAHLIQASERRVHLVVSRQVR 369
Query: 121 GALPELEQE 129
P++ QE
Sbjct: 370 QRSPDIFQE 378
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,000,567
Number of Sequences: 37866
Number of extensions: 597262
Number of successful extensions: 2054
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 1783
Number of HSP's gapped (non-prelim): 289
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.