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Search of human proteins with 63055047
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63055047 hairy and enhancer of split homolog 2 [Homo
sapiens]
(173 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens] 353 4e-98
gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens] 120 4e-28
gi|5031763 hairy and enhancer of split 1 [Homo sapiens] 114 4e-26
gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens] 112 2e-25
gi|58219048 hairy and enhancer of split 5 [Homo sapiens] 79 3e-15
gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens] 77 1e-14
gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens] 76 1e-14
gi|145207994 hairy and enhancer of split 7 [Homo sapiens] 74 6e-14
gi|66912172 hairy and enhancer of split 3 [Homo sapiens] 66 1e-11
gi|105990528 hairy/enhancer-of-split related with YRPW motif 1 i... 62 2e-10
gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Ho... 61 6e-10
gi|105990526 hairy/enhancer-of-split related with YRPW motif 1 i... 60 9e-10
gi|7657154 hairy/enhancer-of-split related with YRPW motif-like ... 60 9e-10
gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens] 53 1e-07
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 44 9e-05
gi|71274142 HES/HEY-like transcription factor [Homo sapiens] 43 2e-04
gi|121114296 caudal type homeobox 1 [Homo sapiens] 42 3e-04
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 42 3e-04
gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens] 42 3e-04
gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens] 42 3e-04
gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens] 42 3e-04
gi|13540521 basic helix-loop-helix domain containing, class B, 3... 41 5e-04
gi|41281612 zinc finger protein 828 [Homo sapiens] 40 0.001
gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 40 0.001
gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sap... 40 0.001
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 40 0.001
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 40 0.001
gi|4507691 transformation/transcription domain-associated protei... 40 0.001
gi|73476377 LBXCOR1 homolog [Homo sapiens] 40 0.001
gi|54792146 tripartite motif-containing 47 [Homo sapiens] 39 0.002
>gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]
Length = 173
Score = 353 bits (906), Expect = 4e-98
Identities = 173/173 (100%), Positives = 173/173 (100%)
Query: 1 MGLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVL 60
MGLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVL
Sbjct: 1 MGLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVL 60
Query: 61 EMTVRFLQELPASSWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLW 120
EMTVRFLQELPASSWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLW
Sbjct: 61 EMTVRFLQELPASSWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLW 120
Query: 121 RRAASATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPPSPPCGPGLWRPW 173
RRAASATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPPSPPCGPGLWRPW
Sbjct: 121 RRAASATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPPSPPCGPGLWRPW 173
>gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]
Length = 221
Score = 120 bits (302), Expect = 4e-28
Identities = 85/197 (43%), Positives = 105/197 (53%), Gaps = 29/197 (14%)
Query: 4 PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63
P + AAE RKS KP++EKRRRARIN+SL+QLK LIL L +E+S SKLEKAD+LEMT
Sbjct: 25 PDKPRSAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMT 84
Query: 64 VRFLQEL---PASSWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLW 120
VR L+ L ++ +A P YR G+ C+A + R L C + V +RLL HL
Sbjct: 85 VRHLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHL- 143
Query: 121 RRAASATLDGGRAGDSSGPSAPAPAPA-------------SAPEPASAP--VPS-----P 160
A L R S P+APA APA P P AP +P P
Sbjct: 144 -AACLRQLGPSRRPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALP 202
Query: 161 PSPPCGP----GLWRPW 173
+P GP G WRPW
Sbjct: 203 AAPRAGPQGPGGPWRPW 219
>gi|5031763 hairy and enhancer of split 1 [Homo sapiens]
Length = 280
Score = 114 bits (285), Expect = 4e-26
Identities = 72/175 (41%), Positives = 92/175 (52%), Gaps = 12/175 (6%)
Query: 4 PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63
P + A+E RKS KP++EKRRRARIN+SLSQLK LIL L +++S SKLEKAD+LEMT
Sbjct: 25 PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84
Query: 64 VRFLQELPASSWPTAA---PLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHL- 119
V+ L+ L + A P YR G+S C+ + R L C + V RLL HL
Sbjct: 85 VKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLA 144
Query: 120 --WRRAASATLDGGRAGDSSGPSAPAPAPAS------APEPASAPVPSPPSPPCG 166
+ + T G P P P P AP P P+P +PP G
Sbjct: 145 NCMTQINAMTYPGQPHPALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGAAPPPG 199
>gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]
Length = 247
Score = 112 bits (279), Expect = 2e-25
Identities = 79/186 (42%), Positives = 99/186 (53%), Gaps = 29/186 (15%)
Query: 15 KSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQEL---P 71
+S KP++EKRRRARIN+SL+QLK LIL L +E+S SKLEKAD+LEMTVR L+ L
Sbjct: 62 QSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLRRVQ 121
Query: 72 ASSWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGG 131
++ +A P YR G+ C+A + R L C + V +RLL HL A L
Sbjct: 122 VTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHL--AACLRQLGPS 179
Query: 132 RAGDSSGPSAPAPAPA-------------SAPEPASAP--VPS-----PPSPPCGP---- 167
R S P+APA APA P P AP +P P +P GP
Sbjct: 180 RRPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPG 239
Query: 168 GLWRPW 173
G WRPW
Sbjct: 240 GPWRPW 245
>gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
Length = 166
Score = 78.6 bits (192), Expect = 3e-15
Identities = 59/163 (36%), Positives = 75/163 (46%), Gaps = 12/163 (7%)
Query: 12 ELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELP 71
E + KP++EK RR RIN S+ QLK L+ R N SKLEKAD+LEM V +L+
Sbjct: 15 EKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAVSYLKHSK 73
Query: 72 ASSWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGG 131
A Y EGYS C+ + L + +LL H R A+
Sbjct: 74 AFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASD--TQMKLLYHFQRPPAAP----- 126
Query: 132 RAGDSSGPSAPAPAPASA-PEPASAPVPSPPSPPCGPGLWRPW 173
A + P AP AP A A+A + P C GLWRPW
Sbjct: 127 -AAPAKEPKAPGAAPPPALSAKATAAAAAAHQPAC--GLWRPW 166
>gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]
Length = 222
Score = 76.6 bits (187), Expect = 1e-14
Identities = 56/159 (35%), Positives = 83/159 (52%), Gaps = 18/159 (11%)
Query: 14 RKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPAS 73
RK+ KPL+EK+RRARIN+SL +L+ L L G E +KLE A+VLE+TVR +Q +
Sbjct: 26 RKARKPLVEKKRRARINESLQELR---LLLAGAE----AKLENAEVLELTVRRVQGVLRG 78
Query: 74 SWPTAAPLPCDS---YREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDG 130
L ++ + GY C+ + + C+ ++ V+A LL HL + +G
Sbjct: 79 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLE--SMPLREG 136
Query: 131 GRAGDSSGPSAPAP--APASAPEPA----SAPVPSPPSP 163
D G + P AP + PA +P+PSPP P
Sbjct: 137 SSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGP 175
>gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]
Length = 224
Score = 76.3 bits (186), Expect = 1e-14
Identities = 56/159 (35%), Positives = 83/159 (52%), Gaps = 16/159 (10%)
Query: 14 RKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPAS 73
RK+ KPL+EK+RRARIN+SL +L+ L L G E +KLE A+VLE+TVR +Q +
Sbjct: 26 RKARKPLVEKKRRARINESLQELR---LLLAGAEVQ--AKLENAEVLELTVRRVQGVLRG 80
Query: 74 SWPTAAPLPCDS---YREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDG 130
L ++ + GY C+ + + C+ ++ V+A LL HL + +G
Sbjct: 81 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLE--SMPLREG 138
Query: 131 GRAGDSSGPSAPAP--APASAPEPA----SAPVPSPPSP 163
D G + P AP + PA +P+PSPP P
Sbjct: 139 SSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGP 177
>gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
Length = 225
Score = 73.9 bits (180), Expect = 6e-14
Identities = 72/227 (31%), Positives = 90/227 (39%), Gaps = 69/227 (30%)
Query: 9 DAAELR---KSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVR 65
D AE R K LKPL+EKRRR RIN+SL +L+ L+L +N KLEKA++LE V
Sbjct: 5 DRAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVG 64
Query: 66 FLQE--------LPASSWPTAAPLPCDSYREGYSACVARLARVL---------------- 101
+L+E +P S A L Y G+ C+ RLA
Sbjct: 65 YLRERSRVEPPGVPRSPVQDAEAL-ASCYLSGFRECLLRLAAFAHDASPAARAQLFSALH 123
Query: 102 -------------------------PACRVLEPAVSARLLEHLW----RRAASATLDGGR 132
PA L PA+ R H R A S +L R
Sbjct: 124 GYLRPKPPRPKPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAWSPSLCSPR 183
Query: 133 AGDSSGPS------APAPAPASAPEPASAPVPSPPSPPCGPGLWRPW 173
AGDS P+ P P P AP+P PP+ WRPW
Sbjct: 184 AGDSGAPAPLTGLLPPPPPPHRQDGAPKAPLPPPPA------FWRPW 224
>gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
Length = 186
Score = 66.2 bits (160), Expect = 1e-11
Identities = 59/185 (31%), Positives = 86/185 (46%), Gaps = 39/185 (21%)
Query: 21 LEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPAS---SWPT 77
+EK+RRARIN SL QLK L+ + KLEKAD+LE++V++++ L S WP
Sbjct: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRK-RKLEKADILELSVKYMRSLQNSLQGLWPV 59
Query: 78 AAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSS 137
S G+ +C+ ++++L + + L+ AA +T+D G +
Sbjct: 60 PRGAEQPS---GFRSCLPGVSQLLRRGDEVGSGLRCPLVP---ESAAGSTMDSAGLGQEA 113
Query: 138 -------GPSAPAPAPAS----APEP------------ASAPVPSPPSPPC--GPGL--- 169
P+ APAPA+ +P P AS P P P S C PGL
Sbjct: 114 PALFRPCTPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLR 173
Query: 170 -WRPW 173
WRPW
Sbjct: 174 VWRPW 178
>gi|105990528 hairy/enhancer-of-split related with YRPW motif 1
isoform a [Homo sapiens]
Length = 304
Score = 62.0 bits (149), Expect = 2e-10
Identities = 58/194 (29%), Positives = 87/194 (44%), Gaps = 40/194 (20%)
Query: 14 RKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPAS 73
RK + ++EKRRR RIN SLS+L+ L+ ++ S +KLEKA++L+MTV L+ L +
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 74 ---SWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPA--VSARLLEHL-----WRRA 123
+ A L D G+ C+A +AR L L+ + + RL+ HL R A
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREA 167
Query: 124 ASATLDG---------------------------GRAGDSSGPSAP-APAPASAPEPASA 155
AS G G AG ++ P+ P + P +
Sbjct: 168 ASGAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPEAP 227
Query: 156 PVPSPPSPPCGPGL 169
+ +PPS GP L
Sbjct: 228 ALRAPPSGSLGPVL 241
>gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Homo
sapiens]
Length = 337
Score = 60.8 bits (146), Expect = 6e-10
Identities = 41/111 (36%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 14 RKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELPAS 73
RK + ++EKRRR RIN SLS+L+ L+ ++ S +KLEKA++L+MTV L+ L A+
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 74 ---SWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPA--VSARLLEHL 119
+ A L D G+ C+ +AR L + L+ + + RL+ HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>gi|105990526 hairy/enhancer-of-split related with YRPW motif 1
isoform b [Homo sapiens]
Length = 308
Score = 60.1 bits (144), Expect = 9e-10
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 40/196 (20%)
Query: 14 RKSLKPLLEKRRRARINQSLSQLKGLILPLLGRE--NSNCSKLEKADVLEMTVRFLQELP 71
RK + ++EKRRR RIN SLS+L+ L+ ++ +KLEKA++L+MTV L+ L
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLH 109
Query: 72 AS---SWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPA--VSARLLEHL-----WR 121
+ + A L D G+ C+A +AR L L+ + + RL+ HL R
Sbjct: 110 TAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQR 169
Query: 122 RAASATLDG---------------------------GRAGDSSGPSAP-APAPASAPEPA 153
AAS G G AG ++ P+ P + P
Sbjct: 170 EAASGAHAGLGHIPWGTVFGHHPHIAHPLLLPQNGHGNAGTTASPTEPHHQGRLGSAHPE 229
Query: 154 SAPVPSPPSPPCGPGL 169
+ + +PPS GP L
Sbjct: 230 APALRAPPSGSLGPVL 245
>gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
[Homo sapiens]
Length = 328
Score = 60.1 bits (144), Expect = 9e-10
Identities = 50/139 (35%), Positives = 70/139 (50%), Gaps = 12/139 (8%)
Query: 12 ELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELP 71
+ RK + ++EKRRR RIN SLS+L+ L+ ++ S SKLEKA+VL+MTV L+ L
Sbjct: 42 QARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVDHLKMLH 99
Query: 72 A---SSWPTAAPLPCDSYREGYSACVARLARVL-----PACRVLEPAVSARLLEHLWRRA 123
A + + A L D G+ C+ + R L P+ R V RLL HL A
Sbjct: 100 ATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRA--DPVRIRLLSHLNSYA 157
Query: 124 ASATLDGGRAGDSSGPSAP 142
A G + P+ P
Sbjct: 158 AEMEPSPTPTGPLAFPAWP 176
>gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]
Length = 412
Score = 53.1 bits (126), Expect = 1e-07
Identities = 51/182 (28%), Positives = 76/182 (41%), Gaps = 33/182 (18%)
Query: 5 RRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTV 64
+R+ D+ E K L+EK+RR RIN+ ++QLK L+ L + + LEKA VLE+T+
Sbjct: 44 KRSEDSKETYKLPHRLIEKKRRDRINECIAQLKDLLPEHL--KLTTLGHLEKAVVLELTL 101
Query: 65 RFLQ-----------------------ELPASSWPTAAPLPCDSYREGYSACVARLARVL 101
+ ++ EL + T + C G+ C + + L
Sbjct: 102 KHVKALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFC----SGFQTCAREVLQYL 157
Query: 102 PACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPP 161
S++L+ HL R S L G G S PS PAP E S+P
Sbjct: 158 AKHENTRDLKSSQLVTHL-HRVVSELLQG---GTSRKPSDPAPKVMDFKEKPSSPAKGSE 213
Query: 162 SP 163
P
Sbjct: 214 GP 215
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 43.5 bits (101), Expect = 9e-05
Identities = 22/43 (51%), Positives = 25/43 (58%), Gaps = 5/43 (11%)
Query: 130 GGRAGDSSGPSAPAPAPASAPEPA----SAPVPSPPSPPCGPG 168
GGR G+S G + PAP P P PA P P PP+PP GPG
Sbjct: 7 GGRPGESPG-ATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPG 48
Score = 28.9 bits (63), Expect = 2.3
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 13/60 (21%)
Query: 101 LPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGPSAP--APAPASAPEPASAPVP 158
LPA + PA+ AR L R +S PS P AP PA++ PAS+ P
Sbjct: 798 LPAAPLAGPALPARRLSR-----------ASRPLSASQPSLPHGAPGPAASTRPASSSTP 846
Score = 28.5 bits (62), Expect = 3.0
Identities = 13/26 (50%), Positives = 14/26 (53%), Gaps = 1/26 (3%)
Query: 142 PAPAPASAPEPASAPVPSPPSPPCGP 167
P PAPA+A P P SPP P P
Sbjct: 763 PGPAPAAA-SPGPPPPASPPGAPASP 787
Score = 26.9 bits (58), Expect = 8.8
Identities = 12/24 (50%), Positives = 12/24 (50%)
Query: 144 PAPASAPEPASAPVPSPPSPPCGP 167
P P AP AS P P SPP P
Sbjct: 761 PPPGPAPAAASPGPPPPASPPGAP 784
>gi|71274142 HES/HEY-like transcription factor [Homo sapiens]
Length = 327
Score = 42.7 bits (99), Expect = 2e-04
Identities = 49/185 (26%), Positives = 75/185 (40%), Gaps = 22/185 (11%)
Query: 2 GLPRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLE 61
G P+ A A++R ++ L+ Q+L + +G L L + KLEKA++LE
Sbjct: 89 GEPQEA--LAQIRSRVRSLVLSSATVPDQQALGRCEGPFLLL-----QSSGKLEKAEILE 141
Query: 62 MTVRFLQELPASSWPTAAPLP------CDSYREGYSACVARLARVLPACRVLEPAVS--A 113
MTV++L+ L ++ +P + + GY C+ L L +E + A
Sbjct: 142 MTVQYLRALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKYA 201
Query: 114 RLLEHLWRRA------ASATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPPSPPCGP 167
R+L L +A A L D S PA + P A V P GP
Sbjct: 202 RILAFLQSKARLGAEPAFPPLGSLPEPDFSYQLHPAGPEFAGHSPGEAAV-FPQGSGAGP 260
Query: 168 GLWRP 172
W P
Sbjct: 261 FPWPP 265
>gi|121114296 caudal type homeobox 1 [Homo sapiens]
Length = 265
Score = 42.0 bits (97), Expect = 3e-04
Identities = 24/53 (45%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
Query: 120 WRRAASATLDGGRAGDSSGPSAPAPAPAS---APEPASAPVPSPPSPPCGPGL 169
W A D A GP+APA +PAS P P +PVP+PP P GPGL
Sbjct: 61 WGAPFPAPKDDWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGP--GPGL 111
Score = 28.5 bits (62), Expect = 3.0
Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 4/36 (11%)
Query: 131 GRAGDSSGPSAPAPAPASAPEPAS----APVPSPPS 162
G + GP AP PAP P+ +S P P+PP+
Sbjct: 24 GLGPQAYGPPAPPPAPPQYPDFSSYSHVEPAPAPPT 59
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 41.6 bits (96), Expect = 3e-04
Identities = 21/29 (72%), Positives = 24/29 (82%), Gaps = 3/29 (10%)
Query: 138 GPSAPA--PAPASAPEPASAPVPSP-PSP 163
GP+APA PAPASAP PASAP P+P P+P
Sbjct: 423 GPAAPAMAPAPASAPAPASAPAPAPVPTP 451
Score = 30.0 bits (66), Expect = 1.0
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Query: 139 PSAPAPAPASAPEPASAPVP-SPPSP 163
P APA AP PASAP P S P+P
Sbjct: 420 PEVGPAAPAMAPAPASAPAPASAPAP 445
Score = 27.3 bits (59), Expect = 6.7
Identities = 13/22 (59%), Positives = 14/22 (63%)
Query: 141 APAPAPASAPEPASAPVPSPPS 162
APA APA AP P A V +P S
Sbjct: 438 APASAPAPAPVPTPAMVSAPSS 459
>gi|56549129 transmembrane anchor protein 1 isoform 3 [Homo sapiens]
Length = 170
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Query: 98 ARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGP-----SAPAPAPASAPEP 152
A +L A L A++ L L RR A+A+ + RA P APAP+ APEP
Sbjct: 5 AELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEP 64
Query: 153 ASAPV-PSPPSPPCGPG 168
A++P P P P G G
Sbjct: 65 AASPAGPEEPGEPAGLG 81
>gi|56549133 transmembrane anchor protein 1 isoform 2 [Homo sapiens]
Length = 177
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Query: 98 ARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGP-----SAPAPAPASAPEP 152
A +L A L A++ L L RR A+A+ + RA P APAP+ APEP
Sbjct: 5 AELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEP 64
Query: 153 ASAPV-PSPPSPPCGPG 168
A++P P P P G G
Sbjct: 65 AASPAGPEEPGEPAGLG 81
>gi|56549131 transmembrane anchor protein 1 isoform 1 [Homo sapiens]
Length = 204
Score = 41.6 bits (96), Expect = 3e-04
Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Query: 98 ARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGP-----SAPAPAPASAPEP 152
A +L A L A++ L L RR A+A+ + RA P APAP+ APEP
Sbjct: 5 AELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEP 64
Query: 153 ASAPV-PSPPSPPCGPG 168
A++P P P P G G
Sbjct: 65 AASPAGPEEPGEPAGLG 81
>gi|13540521 basic helix-loop-helix domain containing, class B, 3
[Homo sapiens]
Length = 482
Score = 41.2 bits (95), Expect = 5e-04
Identities = 48/182 (26%), Positives = 71/182 (39%), Gaps = 34/182 (18%)
Query: 9 DAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQ 68
D + K L+EK+RR RIN+ ++QLK L+ L + + LEKA VLE+T++ L+
Sbjct: 40 DTKDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHL--KLTTLGHLEKAVVLELTLKHLK 97
Query: 69 ELPA----------------SSWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAV- 111
L A S + D++ G+ C + + L P
Sbjct: 98 ALTALTEQQHQKIIALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREP 157
Query: 112 -SARLLEHLWRRAA-----------SATLDGGRAGDSSGPSAPAPAPASAP---EPASAP 156
+L+ HL A L G S+ SA AP A EP +
Sbjct: 158 RCVQLINHLHAVATQFLPTPQLLTQQVPLSKGTGAPSAAGSAAAPCLERAGQKLEPLAYC 217
Query: 157 VP 158
VP
Sbjct: 218 VP 219
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 40.0 bits (92), Expect = 0.001
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 5/58 (8%)
Query: 120 WRRAASATLDGGRAGDSSGPSAPAPAPASAPEP-----ASAPVPSPPSPPCGPGLWRP 172
W + +A+ + ++ ++ P P+P+ +PEP A +P P P+P PG W+P
Sbjct: 257 WGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKP 314
Score = 32.0 bits (71), Expect = 0.27
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 5/37 (13%)
Query: 136 SSGPSAPAPAPASAPEPASAPVPSPPSPPCGPGLWRP 172
SSGP PA P P+ +P P P P PG W+P
Sbjct: 330 SSGPWKPAK-----PAPSVSPGPWKPIPSVSPGPWKP 361
Score = 30.8 bits (68), Expect = 0.61
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 5/43 (11%)
Query: 136 SSGPSAPAPAPASAPEP-----ASAPVPSPPSPPCGPGLWRPW 173
++ P P+PA++PE ++P P PSP P W+P+
Sbjct: 251 AASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPF 293
Score = 30.8 bits (68), Expect = 0.61
Identities = 16/61 (26%), Positives = 27/61 (44%), Gaps = 8/61 (13%)
Query: 120 WRRAASATLDGGRAGDSSGPSAPAPAPASAPEP-------ASAP-VPSPPSPPCGPGLWR 171
W+ + + + R + P + P P +P P +S P P+ P+P PG W+
Sbjct: 290 WKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWK 349
Query: 172 P 172
P
Sbjct: 350 P 350
Score = 28.5 bits (62), Expect = 3.0
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 136 SSGPSAPAPAPASAPEPASAPVPSP-PSPPCGPGLWR 171
S GP P P+ +SA +S+ PS SPP P W+
Sbjct: 355 SPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWK 391
>gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo
sapiens]
Length = 1233
Score = 40.0 bits (92), Expect = 0.001
Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 128 LDGGRAGD--SSGPSAPAPAPASAPEPASAPVPSPPSPPCGP 167
L+GG D SS S+PAP PA P+PASAP P+ P P
Sbjct: 374 LEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVP 415
>gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo
sapiens]
Length = 1268
Score = 40.0 bits (92), Expect = 0.001
Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 128 LDGGRAGD--SSGPSAPAPAPASAPEPASAPVPSPPSPPCGP 167
L+GG D SS S+PAP PA P+PASAP P+ P P
Sbjct: 409 LEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVP 450
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 39.7 bits (91), Expect = 0.001
Identities = 29/91 (31%), Positives = 35/91 (38%), Gaps = 29/91 (31%)
Query: 102 PACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGP---------------------- 139
PA + EP ++A L+E A +GG AG G
Sbjct: 29 PAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSGSAQAASSPAASVGTG 88
Query: 140 ------SAPAPAPASAPEPASAPVPSPPSPP 164
S PAPAPASAP P + P PP PP
Sbjct: 89 VAGGAVSTPAPAPASAPAPGPSAGP-PPGPP 118
Score = 37.7 bits (86), Expect = 0.005
Identities = 17/38 (44%), Positives = 24/38 (63%)
Query: 125 SATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPPS 162
+A++ G AG + APAPA A AP P++ P P PP+
Sbjct: 82 AASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPA 119
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 39.7 bits (91), Expect = 0.001
Identities = 29/91 (31%), Positives = 35/91 (38%), Gaps = 29/91 (31%)
Query: 102 PACRVLEPAVSARLLEHLWRRAASATLDGGRAGDSSGP---------------------- 139
PA + EP ++A L+E A +GG AG G
Sbjct: 29 PAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSGSAQAASSPAASVGTG 88
Query: 140 ------SAPAPAPASAPEPASAPVPSPPSPP 164
S PAPAPASAP P + P PP PP
Sbjct: 89 VAGGAVSTPAPAPASAPAPGPSAGP-PPGPP 118
Score = 37.7 bits (86), Expect = 0.005
Identities = 17/38 (44%), Positives = 24/38 (63%)
Query: 125 SATLDGGRAGDSSGPSAPAPAPASAPEPASAPVPSPPS 162
+A++ G AG + APAPA A AP P++ P P PP+
Sbjct: 82 AASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPA 119
>gi|4507691 transformation/transcription domain-associated protein
[Homo sapiens]
Length = 3830
Score = 39.7 bits (91), Expect = 0.001
Identities = 18/34 (52%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 134 GDSSGPSAPAPAPASAPEPASAPVPSPPSPPCGP 167
G + P+AP PAP+ AP PA P P PP PP P
Sbjct: 486 GVPTAPAAPGPAPSPAPVPAPPP-PPPPPPPATP 518
Score = 35.4 bits (80), Expect = 0.025
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 133 AGDSSGPSAPAPAPASAPEPASAPVPSPPSPPCGP 167
A +++ P P A P P+ APVP+PP PP P
Sbjct: 479 AVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPP 513
Score = 28.5 bits (62), Expect = 3.0
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Query: 134 GDSSGPS-APAPAPASAPEPASAPVPSPPSPP 164
G + P+ PAP P P P + PV P PP
Sbjct: 495 GPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
>gi|73476377 LBXCOR1 homolog [Homo sapiens]
Length = 921
Score = 39.7 bits (91), Expect = 0.001
Identities = 31/100 (31%), Positives = 36/100 (36%), Gaps = 8/100 (8%)
Query: 75 WPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGGRAG 134
WP A LP SY S A A V A A + E L A + G
Sbjct: 448 WPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAAGSGAPEPL--DGAEPAKESGLGA 505
Query: 135 DSSGPSAPAPAPAS------APEPASAPVPSPPSPPCGPG 168
+ PSA + P A P AP+P PP PP G
Sbjct: 506 EERCPSALSRGPLDEDGTDEALPPPLAPLPPPPPPPARKG 545
Score = 29.3 bits (64), Expect = 1.8
Identities = 18/56 (32%), Positives = 19/56 (33%), Gaps = 2/56 (3%)
Query: 116 LEHLWRRAASATLDGGRAGDSSGPSAPAPAP--ASAPEPASAPVPSPPSPPCGPGL 169
L H W + G R G P P E A P P PP P G GL
Sbjct: 251 LSHAWEDVKAMFNGGTRCGAEMAPGPPPHKSLRCGEDEAAGPPGPPPPHPQRGLGL 306
>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
Length = 638
Score = 39.3 bits (90), Expect = 0.002
Identities = 22/38 (57%), Positives = 24/38 (63%), Gaps = 4/38 (10%)
Query: 137 SGP-SAPAPAPASAPEP-ASAPVPSPPSP--PCGPGLW 170
SGP S P PAPA APEP A + +PS P P PC P W
Sbjct: 83 SGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPW 120
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,414,688
Number of Sequences: 37866
Number of extensions: 499600
Number of successful extensions: 21222
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 852
Number of HSP's successfully gapped in prelim test: 661
Number of HSP's that attempted gapping in prelim test: 10079
Number of HSP's gapped (non-prelim): 8843
length of query: 173
length of database: 18,247,518
effective HSP length: 95
effective length of query: 78
effective length of database: 14,650,248
effective search space: 1142719344
effective search space used: 1142719344
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.