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Search of human proteins with 63054872
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63054872 ladybird homeobox 1 [Homo sapiens]
(281 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63054872 ladybird homeobox 1 [Homo sapiens] 560 e-160
gi|57528437 ladybird homeobox 2 [Homo sapiens] 119 3e-27
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens] 82 4e-16
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens] 82 4e-16
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens] 82 5e-16
gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens] 82 5e-16
gi|14149728 BarH-like homeobox 1 [Homo sapiens] 81 1e-15
gi|89257348 homeo box HB9 [Homo sapiens] 79 6e-15
gi|118766339 thyroid transcription factor 1 isoform 1 [Homo sapi... 77 1e-14
gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens] 77 1e-14
gi|31377777 NK2 homeobox 8 [Homo sapiens] 77 1e-14
gi|116805350 homeo box (H6 family) 1 [Homo sapiens] 77 2e-14
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens] 76 4e-14
gi|19923352 NK3 homeobox 1 [Homo sapiens] 75 6e-14
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap... 74 1e-13
gi|6633798 BarH-like homeobox 2 [Homo sapiens] 74 1e-13
gi|11386181 H2.0-like homeobox [Homo sapiens] 73 2e-13
gi|153218470 BarH-like homeobox 1 [Homo sapiens] 72 4e-13
gi|39930383 BarH-like homeobox 2 [Homo sapiens] 72 4e-13
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap... 72 5e-13
gi|157426823 NK2 homeobox 4 [Homo sapiens] 71 9e-13
gi|45593144 gastrulation brain homeo box 2 [Homo sapiens] 71 9e-13
gi|70608170 H6 family homeobox 2 [Homo sapiens] 69 4e-12
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 69 4e-12
gi|12707580 paired-like homeobox 2b [Homo sapiens] 69 4e-12
gi|4506049 hematopoietically expressed homeobox [Homo sapiens] 69 5e-12
gi|4758168 distal-less homeobox 2 [Homo sapiens] 69 6e-12
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap... 69 6e-12
gi|149588930 gastrulation brain homeo box 1 [Homo sapiens] 69 6e-12
gi|4502365 NK3 homeobox 2 [Homo sapiens] 69 6e-12
>gi|63054872 ladybird homeobox 1 [Homo sapiens]
Length = 281
Score = 560 bits (1442), Expect = e-160
Identities = 281/281 (100%), Positives = 281/281 (100%)
Query: 1 MTSKEDGKAAPGEERRRSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHLL 60
MTSKEDGKAAPGEERRRSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHLL
Sbjct: 1 MTSKEDGKAAPGEERRRSPLDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHLL 60
Query: 61 AAADKHAQGGLPLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQ 120
AAADKHAQGGLPLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQ
Sbjct: 61 AAADKHAQGGLPLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQ 120
Query: 121 TPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKL 180
TPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKL
Sbjct: 121 TPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKL 180
Query: 181 KRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPG 240
KRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPG
Sbjct: 181 KRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPG 240
Query: 241 APKAPGAGALQLSPASPLTDQPASSQDCSEDEEDEEIDVDD 281
APKAPGAGALQLSPASPLTDQPASSQDCSEDEEDEEIDVDD
Sbjct: 241 APKAPGAGALQLSPASPLTDQPASSQDCSEDEEDEEIDVDD 281
>gi|57528437 ladybird homeobox 2 [Homo sapiens]
Length = 194
Score = 119 bits (298), Expect = 3e-27
Identities = 78/172 (45%), Positives = 92/172 (53%), Gaps = 43/172 (25%)
Query: 110 RDGMTIFGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQV 169
R G G +KRRKSRTAFT Q+ ELE+RF++QKYL+P++RD +A +LGL NAQV
Sbjct: 66 RAGPDALGPGPFGRKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQV 125
Query: 170 ITWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAK 229
+TWFQNRRAKLKRD+EEM+ADV S + L P L L
Sbjct: 126 VTWFQNRRAKLKRDVEEMRADVASLRALSPE------VLCSL------------------ 161
Query: 230 SRPGSPVLPPGAPKAPGAGALQLSPASPLTDQPASSQDCSEDEEDEEIDVDD 281
LP GAP PG L L PA P D DEEI VDD
Sbjct: 162 ------ALPEGAPD-PG---LCLGPAGP---------DSRPHLSDEEIQVDD 194
>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
Length = 330
Score = 82.4 bits (202), Expect = 4e-16
Identities = 56/140 (40%), Positives = 78/140 (55%), Gaps = 7/140 (5%)
Query: 60 LAAADKHAQGGLPLA-GRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQ 118
LA A H Q PLA G + + + L TF +E + + G Q
Sbjct: 140 LAGAVAHPQ---PLATGLPTVPSVPAMPGVNNLTGLTFPWMESNRRYTKDRFTGHPY--Q 194
Query: 119 RQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRA 178
+TP K++K RT+FT QI ELEKRF QKYL+ A+R +A+ L +T+AQV TWFQNRR
Sbjct: 195 NRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRT 254
Query: 179 KLKRD-LEEMKADVESAKKL 197
K +R EE +A+ + A ++
Sbjct: 255 KWRRQTAEEREAERQQANRI 274
>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
Length = 284
Score = 82.4 bits (202), Expect = 4e-16
Identities = 52/123 (42%), Positives = 70/123 (56%), Gaps = 24/123 (19%)
Query: 118 QRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRR 177
Q +TP KR+K RT+F+ Q+ ELE+RFL QKYL+ A+R +A+ L +T+AQV TWFQNRR
Sbjct: 150 QNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRR 209
Query: 178 AKLKRD-LEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPV 236
K +R EE +A+ A +L L L+Q+ A RP P
Sbjct: 210 TKWRRQTAEEREAERHRAGRL----------LLHLQQD-------------ALPRPLRPP 246
Query: 237 LPP 239
LPP
Sbjct: 247 LPP 249
>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
Length = 324
Score = 82.0 bits (201), Expect = 5e-16
Identities = 84/278 (30%), Positives = 114/278 (41%), Gaps = 47/278 (16%)
Query: 34 TPFSIEDILNKPSVRRSYSLCG--AAHLLA-----------------AADKHAQGGLPLA 74
TPFS++DILN +RS + G +A L A A + A GLP
Sbjct: 10 TPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPEL 69
Query: 75 GRALLSQTSPL-CALEELASKTF----------------KGLEVSVLQ-AAEGRDGMTIF 116
L SP CA A+ F + E+ LQ A E
Sbjct: 70 RAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADN 129
Query: 117 GQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNR 176
+R ++RRK R F+ Q+YELE+RF Q+YLS +RDQ+A L LT+ QV WFQNR
Sbjct: 130 AERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNR 189
Query: 177 RAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPV 236
R K KR ++ ++ P I A+ L ++ + G A +P
Sbjct: 190 RYKCKRQRQDQTLELVGLPPPPPPPARRI-AVPVLVRDGKPCLGDSAPYAPAYGVGLNPY 248
Query: 237 LPPGAPKAPGAGALQLS---------PASPLTDQPASS 265
P PG G S PA P QPA++
Sbjct: 249 GYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATA 286
>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
Length = 291
Score = 82.0 bits (201), Expect = 5e-16
Identities = 43/81 (53%), Positives = 58/81 (71%), Gaps = 1/81 (1%)
Query: 118 QRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRR 177
Q +TP KR+K RT+F+ QI ELEKRF QKYL+ A+R +A+ L +T+AQV TWFQNRR
Sbjct: 159 QNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRR 218
Query: 178 AKLKRD-LEEMKADVESAKKL 197
K +R EE +A+ + A +L
Sbjct: 219 TKWRRQTAEEREAERQQASRL 239
>gi|14149728 BarH-like homeobox 1 [Homo sapiens]
Length = 327
Score = 80.9 bits (198), Expect = 1e-15
Identities = 67/192 (34%), Positives = 87/192 (45%), Gaps = 30/192 (15%)
Query: 2 TSKEDGKAAPGEERRRSPLDHLPPPANSNKPLTPFSIEDILN--KPSVRRSYSLCGAAHL 59
T + G + PG + P L PA S + F I DIL KP
Sbjct: 63 TPRPGGASGPGLDSHLQP-GQLSAPAQSRTVTSSFLIRDILADCKP-------------- 107
Query: 60 LAAADKHAQGGLPLA----GRALLSQTSPLC-ALEELASKTFKGLEVSVLQAAEGRDGMT 114
LAA ++ G P A GR L++ S E V + +
Sbjct: 108 LAACAPYSSSGQPAAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDRE---- 163
Query: 115 IFGQRQTP----KKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVI 170
I R +P KK RK+RTAFT+HQ+ +LE+ F QKYLS DR ++A L LT+ QV
Sbjct: 164 ISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVK 223
Query: 171 TWFQNRRAKLKR 182
TW+QNRR K KR
Sbjct: 224 TWYQNRRTKWKR 235
>gi|89257348 homeo box HB9 [Homo sapiens]
Length = 401
Score = 78.6 bits (192), Expect = 6e-15
Identities = 59/155 (38%), Positives = 75/155 (48%), Gaps = 30/155 (19%)
Query: 124 KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRD 183
K R+ RTAFT+ Q+ ELE +F KYLS R ++A L LT QV WFQNRR K KR
Sbjct: 240 KCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKR- 298
Query: 184 LEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGR-AKSRPGS-PVLPPGA 241
+KK A + Q +E GGGGG G+ PG+ +L P A
Sbjct: 299 ----------SKK----------AKEQAAQEAEKQKGGGGGAGKGGAEEPGAEELLGPPA 338
Query: 242 PKAPGAGALQLSPASPLTDQPASSQDCSEDEEDEE 276
P G+G L D S + EDE+DE+
Sbjct: 339 PGDKGSG-------RRLRDLRDSDPEEDEDEDDED 366
Score = 28.1 bits (61), Expect = 9.0
Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 205 IVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPGAPKAPGAGALQLSPASP 257
+ + L + T GGGGG G + GS P + + P A A +L SP
Sbjct: 28 LALVTSLAAAASGTGGGGGGGGASGGTSGS--CSPASSEPPAAPADRLRAESP 78
>gi|118766339 thyroid transcription factor 1 isoform 1 [Homo
sapiens]
Length = 401
Score = 77.4 bits (189), Expect = 1e-14
Identities = 55/142 (38%), Positives = 70/142 (49%), Gaps = 34/142 (23%)
Query: 125 RRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDL 184
RRK R F+ Q+YELE+RF QKYLS +R+ +A + LT QV WFQN R K+KR
Sbjct: 191 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQA 250
Query: 185 EEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGG-GCGRAKS-------RPGSPV 236
+ D A +L+Q+S GGGG GC + + R PV
Sbjct: 251 K------------------DKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPV 292
Query: 237 L-------PPGAPKAPGAGALQ 251
L GAP APGA +LQ
Sbjct: 293 LVKDGKPCQAGAP-APGAASLQ 313
>gi|4507715 thyroid transcription factor 1 isoform 2 [Homo sapiens]
Length = 371
Score = 77.4 bits (189), Expect = 1e-14
Identities = 55/142 (38%), Positives = 70/142 (49%), Gaps = 34/142 (23%)
Query: 125 RRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDL 184
RRK R F+ Q+YELE+RF QKYLS +R+ +A + LT QV WFQN R K+KR
Sbjct: 161 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQA 220
Query: 185 EEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGG-GCGRAKS-------RPGSPV 236
+ D A +L+Q+S GGGG GC + + R PV
Sbjct: 221 K------------------DKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPV 262
Query: 237 L-------PPGAPKAPGAGALQ 251
L GAP APGA +LQ
Sbjct: 263 LVKDGKPCQAGAP-APGAASLQ 283
>gi|31377777 NK2 homeobox 8 [Homo sapiens]
Length = 239
Score = 77.4 bits (189), Expect = 1e-14
Identities = 56/152 (36%), Positives = 74/152 (48%), Gaps = 11/152 (7%)
Query: 123 KKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKR 182
+KR+K R F+ Q ELE+RF Q+YLS +R+Q+A L LT QV WFQN R KLKR
Sbjct: 82 EKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKR 141
Query: 183 DLEEMKAD----VESAKKLGPSGQMDIVALAELEQNSEATAGGGG---GCGRAKSRPGSP 235
A+ SA+ G + V + L ++ + GGGG G A+ + G+P
Sbjct: 142 ARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCGGGGGGEVGTAAAQEKCGAP 201
Query: 236 VLP----PGAPKAPGAGALQLSPASPLTDQPA 263
PG P AL L PA PA
Sbjct: 202 PAAACPLPGYPAFGPGSALGLFPAYQHLASPA 233
>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
Length = 348
Score = 76.6 bits (187), Expect = 2e-14
Identities = 67/204 (32%), Positives = 100/204 (49%), Gaps = 20/204 (9%)
Query: 67 AQGGLPLA-GRALLSQTSPLCALEELASKTFKGLEVSVLQAAEG--RDGMTIFGQRQTPK 123
A+G P G + + + A A+ T + E++ + AA G R G+ + G R
Sbjct: 147 AEGAWPRGPGPGAVQREAAELAARGPAAGTEEASELAEVPAAAGETRGGVGVGGGR---- 202
Query: 124 KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRD 183
++K+RT F+ Q+++LE F ++YLS A+R +A L LT QV WFQNRR K KR
Sbjct: 203 -KKKTRTVFSRSQVFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKR- 260
Query: 184 LEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRA--KSRPGSPVLPPGA 241
++ A++E+A L P G +V + L S A G P +P PP
Sbjct: 261 --QLAAELEAA-SLSPPGAQRLVRVPVLYHESPPAAAAAGPPATLPFPLAPAAPAPPP-- 315
Query: 242 PKAPGAGALQLSPASPLTDQPASS 265
P +GAL A PL PA++
Sbjct: 316 PLLGFSGAL----AYPLAAFPAAA 335
>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
Length = 283
Score = 75.9 bits (185), Expect = 4e-14
Identities = 52/143 (36%), Positives = 72/143 (50%), Gaps = 12/143 (8%)
Query: 122 PKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLK 181
P++ +++RTA+T Q+ ELEK FL+ KY+S R ++A L LT + WFQNRR K K
Sbjct: 143 PEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWK 202
Query: 182 RDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPGA 241
+ E KK G + +AE EQ+ T+G PG V PP A
Sbjct: 203 K---------EEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAV-PPAA 252
Query: 242 PKAPGAGALQLSPASPLTDQPAS 264
P A G +L P + QP+S
Sbjct: 253 PVAAREG--RLPPGLSASPQPSS 273
>gi|19923352 NK3 homeobox 1 [Homo sapiens]
Length = 234
Score = 75.1 bits (183), Expect = 6e-14
Identities = 64/180 (35%), Positives = 87/180 (48%), Gaps = 9/180 (5%)
Query: 26 PANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHL--LAAADKHAQGGLPLAGRALLS-QT 82
P +KPLT F I+DIL + R+ + +GG AG T
Sbjct: 19 PPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEPEGGRSRAGAQNDQLST 78
Query: 83 SPLCALEE---LASKTFKGLEVSVLQAAEGRDGMTIFGQRQTPKK-RRKSRTAFTNHQIY 138
P A EE LA + S L +E G + QTPK+ +++SR AF++ Q+
Sbjct: 79 GPRAAPEEAETLAETEPERHLGSYLLDSENTSG-ALPRLPQTPKQPQKRSRAAFSHTQVI 137
Query: 139 ELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKR-DLEEMKADVESAKKL 197
ELE++F +QKYLS +R +A+ L LT QV WFQNRR K KR L D+E L
Sbjct: 138 ELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSL 197
>gi|148746211 NK2 transcription factor related, locus 3 [Homo
sapiens]
Length = 364
Score = 74.3 bits (181), Expect = 1e-13
Identities = 60/202 (29%), Positives = 86/202 (42%), Gaps = 33/202 (16%)
Query: 60 LAAADKHAQGGLPLAG---RALLSQTSPLCALEE----LASKTFKGLEVSVLQAAEGRDG 112
LAAAD H GL G L S EE + ++ K ++ G
Sbjct: 76 LAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQKSCQLKKSLETAGDCK 135
Query: 113 MTIFGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITW 172
+R P+ RRK R F+ Q++ELE+RF Q+YLS +R+ +A L LT+ QV W
Sbjct: 136 AAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIW 195
Query: 173 FQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRP 232
FQNRR K KR ++ ++ + P ++ + L R
Sbjct: 196 FQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLV---------------------RD 234
Query: 233 GSPVLPP-----GAPKAPGAGA 249
G P + P GAP + GA A
Sbjct: 235 GKPCVTPSAQAYGAPYSVGASA 256
>gi|6633798 BarH-like homeobox 2 [Homo sapiens]
Length = 279
Score = 73.9 bits (180), Expect = 1e-13
Identities = 54/153 (35%), Positives = 73/153 (47%), Gaps = 5/153 (3%)
Query: 118 QRQTP--KKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQN 175
++ TP KK R+SRT FT Q+ LEK+F QKYLS DR +AQ LGLT QV TW+QN
Sbjct: 124 EQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQN 183
Query: 176 RRAKLKRDLEEMKADVES-AKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGS 234
RR K K+ + +K E+ K G + I E+E + + G S+
Sbjct: 184 RRMKWKKMV--LKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEPSQGQE 241
Query: 235 PVLPPGAPKAPGAGALQLSPASPLTDQPASSQD 267
+ PKA P P + P S +
Sbjct: 242 ELCEAQEPKARDVPLEMAEPPDPPQELPIPSSE 274
>gi|11386181 H2.0-like homeobox [Homo sapiens]
Length = 488
Score = 73.2 bits (178), Expect = 2e-13
Identities = 73/199 (36%), Positives = 97/199 (48%), Gaps = 35/199 (17%)
Query: 26 PANSNKPLTPFSIEDILNK---PSVRRSYSLCGAAHLLAA---ADKHAQGGLPLAGR--- 76
PA S+K L F I+ IL+ P V+ +L LL A H G P AG+
Sbjct: 167 PAPSSKDLK-FGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFA 225
Query: 77 ---------ALLS--QTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQTPKKR 125
A+LS ++P +++ TF G A +D M QT K++
Sbjct: 226 SLDPINEASAILSPLNSNPRNSVQHQFQDTFPGP-----YAVLTKDTMP-----QTYKRK 275
Query: 126 RK-SRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDL 184
R SR F+N Q LEKRF QKY++ DR Q+A LGLT+AQV WFQNRR K R
Sbjct: 276 RSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKW-RHS 334
Query: 185 EEMKADVESAKKLG--PSG 201
+E +A + K+ G PSG
Sbjct: 335 KEAQAQKDKDKEAGEKPSG 353
>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
Length = 254
Score = 72.4 bits (176), Expect = 4e-13
Identities = 70/202 (34%), Positives = 92/202 (45%), Gaps = 39/202 (19%)
Query: 11 PGEERRRSP---LDHLPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHLLAAADKHA 67
PG R P DH P S F IE+IL +P + + AA AAA +
Sbjct: 7 PGAARFGPPEGCADHRPHRYRS------FMIEEILTEPPGPKGAAPAAAA---AAAGELL 57
Query: 68 QGGLP--LAGRALLSQTSPLCALEE------LASKTFKGLEVSVLQAAEGRDG------- 112
+ G+ LA R S + L A + LA GL ++L A G G
Sbjct: 58 KFGVQALLAARPFHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLAAGPGLPGAAGAPHL 117
Query: 113 ---MTIFGQRQTP---------KKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQ 160
+ + G+ + KK R+SRT FT Q+ LEKRF QKYLS DR +A+
Sbjct: 118 PLELQLRGKLEAAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAE 177
Query: 161 QLGLTNAQVITWFQNRRAKLKR 182
LGL+ QV TW+QNRR K K+
Sbjct: 178 SLGLSQLQVKTWYQNRRMKWKK 199
>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
Length = 387
Score = 72.4 bits (176), Expect = 4e-13
Identities = 38/72 (52%), Positives = 49/72 (68%), Gaps = 4/72 (5%)
Query: 115 IFGQRQTP----KKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVI 170
I R++P KK RK+RTAF++HQ+ +LE+ F QKYLS DR +A L LT+ QV
Sbjct: 218 ITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVK 277
Query: 171 TWFQNRRAKLKR 182
TW+QNRR K KR
Sbjct: 278 TWYQNRRTKWKR 289
>gi|210147470 NK2 transcription factor related, locus 6 [Homo
sapiens]
Length = 219
Score = 72.0 bits (175), Expect = 5e-13
Identities = 56/168 (33%), Positives = 81/168 (48%), Gaps = 16/168 (9%)
Query: 109 GRDGMTIFGQR-QTPK--KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLT 165
G G ++ G R + PK +RRK R F+ Q+ LE+RF Q+YLS +R+ +A L LT
Sbjct: 31 GNSGDSVRGGRSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLT 90
Query: 166 NAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGC 225
+ QV WFQNRR K KR ++ ++ + L P VA+ L ++ + G G G
Sbjct: 91 STQVKIWFQNRRYKCKRQRQDKSLEL-AGHPLTPRR----VAVPVLVRDGKPCLGPGPGA 145
Query: 226 GRAKSRPGSPVLP-------PGAPKAPGAGALQL-SPASPLTDQPASS 265
S + V P GAP G G +P+ P P +S
Sbjct: 146 PAFPSPYSAAVSPYSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLAS 193
>gi|157426823 NK2 homeobox 4 [Homo sapiens]
Length = 354
Score = 71.2 bits (173), Expect = 9e-13
Identities = 50/143 (34%), Positives = 69/143 (48%), Gaps = 11/143 (7%)
Query: 125 RRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDL 184
RRK R F+ Q+YELE+RF QKYLS +R+ +A + LT QV WFQN R K+KR
Sbjct: 189 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQA 248
Query: 185 EEMKA-DVESAKKLG----PSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPP 239
++ A ++ LG P VA+ L ++ + G + PG P
Sbjct: 249 KDKAAQQLQQEGGLGPPPPPPPSPRRVAVPVLVKDGKPCQNGA-----STPTPGQAGPQP 303
Query: 240 GAPKAPGAGALQLSPASPLTDQP 262
AP P +LSP+ P P
Sbjct: 304 PAP-TPAPELEELSPSPPALHGP 325
>gi|45593144 gastrulation brain homeo box 2 [Homo sapiens]
Length = 348
Score = 71.2 bits (173), Expect = 9e-13
Identities = 43/90 (47%), Positives = 53/90 (58%), Gaps = 4/90 (4%)
Query: 117 GQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNR 176
G + K R+ RTAFT+ Q+ ELEK F +KYLS +R QIA L L+ QV WFQNR
Sbjct: 239 GSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNR 298
Query: 177 RAKLKRDLEEMKADVESAKKLGPSGQMDIV 206
RAK KR +KA ++K PS IV
Sbjct: 299 RAKWKR----VKAGNANSKTGEPSRNPKIV 324
>gi|70608170 H6 family homeobox 2 [Homo sapiens]
Length = 273
Score = 69.3 bits (168), Expect = 4e-12
Identities = 36/85 (42%), Positives = 53/85 (62%), Gaps = 3/85 (3%)
Query: 118 QRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRR 177
+RQ ++K+RT F+ Q+Y+LE F ++YLS ++R +A L LT QV TWFQNRR
Sbjct: 142 ERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRR 201
Query: 178 AKLKRDLEEMKADVESAKKLGPSGQ 202
K KR ++ A++E+A S Q
Sbjct: 202 NKWKR---QLSAELEAANMAHASAQ 223
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 69.3 bits (168), Expect = 4e-12
Identities = 60/185 (32%), Positives = 84/185 (45%), Gaps = 15/185 (8%)
Query: 84 PLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQTPKKRRKSRTAFTNHQIYELEKR 143
P C E ++ GL V A G ++ + Q KK R++RT FT +Q++ELE+
Sbjct: 100 PYCPKEPGEARPSPGLPVG---PATGEAKLS--EEEQPKKKHRRNRTTFTTYQLHELERA 154
Query: 144 FLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRD--LEEMKADVESAKKLGPSG 201
F Y R+++A ++ L +V WFQNRRAK +R LE ++ + L S
Sbjct: 155 FEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSR 214
Query: 202 QMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPGAPKAPGAGALQLSP--ASPLT 259
L+ L + G GG +S G P LP G GA ALQ P P
Sbjct: 215 SPPSATLSPLGAGPGSGGGPAGGALPLESWLGPP-LPGG-----GATALQSLPGFGPPAQ 268
Query: 260 DQPAS 264
PAS
Sbjct: 269 SLPAS 273
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 69.3 bits (168), Expect = 4e-12
Identities = 50/146 (34%), Positives = 72/146 (49%), Gaps = 13/146 (8%)
Query: 114 TIFGQRQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWF 173
T G +K+R+ RT FT+ Q+ ELE+ F Y R+++A ++ LT A+V WF
Sbjct: 87 TDHGGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWF 146
Query: 174 QNRRAKLKRDLEEMKADVESAKKLGPSGQMDIVALAELEQNSEAT----AGGGG------ 223
QNRRAK ++ E A +A K G SG+ + + + +++T GG G
Sbjct: 147 QNRRAKFRKQ-ERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPT 205
Query: 224 -GCGRAKSRPGSPVLPPGAPKAPGAG 248
CG G P P GAP A G G
Sbjct: 206 PSCGANGGGGGGP-SPAGAPGAAGPG 230
>gi|4506049 hematopoietically expressed homeobox [Homo sapiens]
Length = 270
Score = 68.9 bits (167), Expect = 5e-12
Identities = 53/160 (33%), Positives = 78/160 (48%), Gaps = 37/160 (23%)
Query: 124 KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRD 183
KR+ + F+N Q ELEK+F QKYLSP +R ++A+ L L+ QV TWFQNRRAK +R
Sbjct: 136 KRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRL 195
Query: 184 LEEMKADVESAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPGAPK 243
+E + +S KK ELE + C + + LP K
Sbjct: 196 KQE---NPQSNKK------------EELESLDSS-------CDQRQD------LPSEQNK 227
Query: 244 APGAGALQLSPASPLTDQPASSQDCS---EDEEDEEIDVD 280
+ Q SP+ PAS +D ++ D+E+D++
Sbjct: 228 GASLDSSQCSPS------PASQEDLESEISEDSDQEVDIE 261
>gi|4758168 distal-less homeobox 2 [Homo sapiens]
Length = 328
Score = 68.6 bits (166), Expect = 6e-12
Identities = 43/123 (34%), Positives = 61/123 (49%), Gaps = 3/123 (2%)
Query: 122 PKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLK 181
PKK RK RT +++ Q+ L++RF +YL+ +R ++A LGLT QV WFQNRR+K K
Sbjct: 149 PKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFK 208
Query: 182 RDLEEMKADVE---SAKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLP 238
+ + + E A P + A A + GGGG G S GS
Sbjct: 209 KMWKSGEIPSEQHPGASASPPCASPPVSAPASWDFGVPQRMAGGGGPGSGGSGAGSSGSS 268
Query: 239 PGA 241
P +
Sbjct: 269 PSS 271
>gi|111120318 NK6 transcription factor related, locus 1 [Homo
sapiens]
Length = 367
Score = 68.6 bits (166), Expect = 6e-12
Identities = 80/287 (27%), Positives = 107/287 (37%), Gaps = 73/287 (25%)
Query: 20 LDHLPPPANSNKPLTPFSIEDILNKPSV-------------------------RRSYSLC 54
L L P TP I DIL++PS+ S S
Sbjct: 80 LSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAA 139
Query: 55 GAAHLLAAADKHAQGGLPLAGRALLSQTSP------LCALEELASKTFKGLEVSVLQAAE 108
AA AAA + GL LAG S SP L A+ G L
Sbjct: 140 AAAAAAAAAAASSPAGL-LAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELP 198
Query: 109 GRDGMTIFGQRQTPK---------------------KRRKSRTAFTNHQIYELEKRFLYQ 147
GR + G Q+P KR+ +R F+ QI+ LEK F
Sbjct: 199 GRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQT 258
Query: 148 KYLSPADRDQIAQQLGLTNAQVITWFQNRRAK-LKRDLEEM-----KADVESAKKLGPS- 200
KYL+ +R ++A LG+T +QV WFQNRR K K+ EM K D E+ + G S
Sbjct: 259 KYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGASE 318
Query: 201 -------------GQMDIVALAELEQNSEATAGGGGGCGRAKSRPGS 234
D + +L + ++++GGGGG S P S
Sbjct: 319 NEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGLLLHASEPES 365
>gi|149588930 gastrulation brain homeo box 1 [Homo sapiens]
Length = 363
Score = 68.6 bits (166), Expect = 6e-12
Identities = 35/59 (59%), Positives = 41/59 (69%)
Query: 124 KRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKR 182
K R+ RTAFT+ Q+ ELEK F +KYLS +R QIA L L+ QV WFQNRRAK KR
Sbjct: 260 KSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 318
>gi|4502365 NK3 homeobox 2 [Homo sapiens]
Length = 333
Score = 68.6 bits (166), Expect = 6e-12
Identities = 37/71 (52%), Positives = 49/71 (69%), Gaps = 3/71 (4%)
Query: 122 PKKRRK-SRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKL 180
PK R+K SR AF++ Q++ELE+RF +Q+YLS +R +A L LT QV WFQNRR K
Sbjct: 202 PKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKT 261
Query: 181 KRDLEEMKADV 191
KR +M AD+
Sbjct: 262 KR--RQMAADL 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,698,003
Number of Sequences: 37866
Number of extensions: 662582
Number of successful extensions: 5467
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 322
Number of HSP's successfully gapped in prelim test: 146
Number of HSP's that attempted gapping in prelim test: 4740
Number of HSP's gapped (non-prelim): 822
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.