Search of human proteins with 62953127

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62953127 polyhomeotic 1-like [Homo sapiens]
         (1004 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62953127 polyhomeotic 1-like [Homo sapiens]                       1961   0.0  
gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]              360   5e-99
gi|148612879 polyhomeotic like 3 [Homo sapiens]                       290   6e-78
gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens]              257   3e-68
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]      126   9e-29
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]      123   8e-28
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    95   3e-19
gi|56549696 E1A binding protein p400 [Homo sapiens]                    84   7e-16
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     82   2e-15
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     82   2e-15
gi|110347429 mediator complex subunit 12 [Homo sapiens]                78   4e-14
gi|33286444 mastermind-like 2 [Homo sapiens]                           76   1e-13
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom...    76   1e-13
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo...    76   1e-13
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho...    76   1e-13
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho...    76   1e-13
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom...    76   1e-13
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   75   3e-13
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 75   3e-13
gi|22538413 forkhead box P2 isoform III [Homo sapiens]                 73   1e-12
gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens]            71   6e-12
gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens]            71   6e-12
gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens]            71   6e-12
gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens]     71   6e-12
gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens]                    70   1e-11
gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens]                    70   1e-11
gi|158138528 l(3)mbt-like 4 [Homo sapiens]                             70   1e-11
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              69   2e-11
gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]    69   2e-11
gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens]    69   2e-11

>gi|62953127 polyhomeotic 1-like [Homo sapiens]
          Length = 1004

 Score = 1961 bits (5080), Expect = 0.0
 Identities = 1004/1004 (100%), Positives = 1004/1004 (100%)

Query: 1    METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ 60
            METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ
Sbjct: 1    METESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQ 60

Query: 61   QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV 120
            QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV
Sbjct: 61   QLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSV 120

Query: 121  SSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPN 180
            SSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPN
Sbjct: 121  SSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPN 180

Query: 181  GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL 240
            GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL
Sbjct: 181  GAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSL 240

Query: 241  SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG 300
            SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG
Sbjct: 241  SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG 300

Query: 301  GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA 360
            GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA
Sbjct: 301  GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA 360

Query: 361  PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH 420
            PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH
Sbjct: 361  PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH 420

Query: 421  LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS 480
            LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS
Sbjct: 421  LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSS 480

Query: 481  PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA 540
            PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA
Sbjct: 481  PLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQA 540

Query: 541  QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG 600
            QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG
Sbjct: 541  QALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQG 600

Query: 601  TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP 660
            TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP
Sbjct: 601  TAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLP 660

Query: 661  AKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMG 720
            AKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMG
Sbjct: 661  AKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMG 720

Query: 721  DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG 780
            DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG
Sbjct: 721  DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGG 780

Query: 781  PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK 840
            PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK
Sbjct: 781  PLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRK 840

Query: 841  KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG 900
            KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG
Sbjct: 841  KMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPG 900

Query: 901  PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE 960
            PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE
Sbjct: 901  PLSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAE 960

Query: 961  EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET 1004
            EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET
Sbjct: 961  EFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET 1004


>gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]
          Length = 858

 Score =  360 bits (923), Expect = 5e-99
 Identities = 349/1063 (32%), Positives = 460/1063 (43%), Gaps = 282/1063 (26%)

Query: 3    TESEQNSNSTNG--SSSSGGSSRPQIAQMSLY----ERQAVQALQ-ALQRQPN-AAQYFH 54
            T S   ++S++G  +SSSGGS RP   Q+S+Y    +RQ VQ +Q AL RQP+ AAQY  
Sbjct: 17   TSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQ 76

Query: 55   QF--------------MLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQ 100
            Q               + QQ LS+AQL SLAAVQQA++ ++RQ S+   S    Q     
Sbjct: 77   QMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSG-SNVSAQAPAQS 135

Query: 101  ASINLATT-SAAQLISRSQSVSSPSATTLTQ-SVLLGNTTSPPLNQSQAQMYLRPQLGNL 158
            +SINLA + +AAQL++R+QSV+S +A+ + Q +VLLGNT+SP L  SQAQMYLR Q+   
Sbjct: 136  SSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQM--- 192

Query: 159  LQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQ 218
                            LI  P   VA VQ E+                            
Sbjct: 193  ----------------LIFTPTATVATVQPEL---------------------------- 208

Query: 219  GPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQ---SLNLSQAGGGSGNSI 275
                 G+   A PP  + V +L+  + Q  A A +    T     SL L    GGS    
Sbjct: 209  -----GTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGS---- 259

Query: 276  PGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPA-AQTVTVSQGSQTEAESA 334
                                                 QPLP  AQ+   +Q S   A+  
Sbjct: 260  -------------------------------------QPLPTPAQSRNTAQASPAGAKPG 282

Query: 335  AA-------KKAEADGS--GQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQ 385
             A       KK + + S  G       L+RT     +  LI+ A Y Q+QPH L+ Q   
Sbjct: 283  IADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPA-YAQLQPHQLLPQPSS 341

Query: 386  IHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTL 445
             HLQ + V+                               QQQ Q QQQQ   Q     L
Sbjct: 342  KHLQPQFVI-------------------------------QQQPQPQQQQPPPQQSRPVL 370

Query: 446  TAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPI 505
             A   PQ+         Q   +A  + + P+  + PL  P     KP    Q  PP  P 
Sbjct: 371  QAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPP-TPD 429

Query: 506  KPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSG 565
              PQ G        +  PH P +          Q  +  + QL  A P  + +P   +  
Sbjct: 430  TGPQNG------HPEGVPHTPQR--------RFQHTSAVILQLQPASPPQQCVPDDWKEV 475

Query: 566  QAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYM 625
                 S P +   P   Q+   T  PG              G    +SP +   PA    
Sbjct: 476  APGEKSVPETRSGPSPHQQAIVTAMPG--------------GLPVPTSPNIQPSPA---- 517

Query: 626  QSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAES 685
               H  G+    A+           D+S+ G                             
Sbjct: 518  ---HETGQGIVHAL----------TDLSSPG----------------------------- 535

Query: 686  VANVNANTPSSELVALTPAPSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQE 745
            + + N N+ SS +    P      P  A+V  Q+              LTH+IEGFVIQE
Sbjct: 536  MTSGNGNSASS-IAGTAPQNGENKPPQAIVKPQI--------------LTHVIEGFVIQE 580

Query: 746  GAEPFPVGCSQLL------KESEKPLQTGLP----TGLTENQSGGPLGVDSPSAELDKKA 795
            GAEPFPVG S LL      K ++  L   LP    T  T+++   P   +S       K 
Sbjct: 581  GAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLK- 639

Query: 796  NLLKCEYCGKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFRLKRKKMKEFQEANYA-RVR 854
              LKCE CG+   A +F+ SKRFCSM CAKRYNV C+ +  L      + Q+A  A   R
Sbjct: 640  --LKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNR 697

Query: 855  RRGPRRSSSDIAR-AKIQG------------KCHRGQEDSSRGSDNSSYDEALSPTSPGP 901
            RR  + S   + +  K Q             +    QEDSSR SDNSSY+E LSP S   
Sbjct: 698  RRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASS 757

Query: 902  LSVRAGHGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEE 961
             + R   G+RDL  P+      +L G+   FL S P++W+VE+VYEFI SL GCQEIAEE
Sbjct: 758  STSRRRQGQRDLELPDM--HMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEE 815

Query: 962  FRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAKINVLKET 1004
            FR+QEIDGQALLLLKE+HLMSAMNIKLGPALKI A+I++LK++
Sbjct: 816  FRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS 858


>gi|148612879 polyhomeotic like 3 [Homo sapiens]
          Length = 995

 Score =  290 bits (741), Expect = 6e-78
 Identities = 332/1096 (30%), Positives = 462/1096 (42%), Gaps = 205/1096 (18%)

Query: 1    METESEQNSNSTNGSSSSG-------GSSRPQIAQMSLY---ERQAVQALQ-ALQRQPN- 48
            M+TE    ++S + ++SS         SSR Q  Q+S+Y   +R AVQ +Q AL R P+ 
Sbjct: 13   MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSS 72

Query: 49   AAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATT 108
            AAQY                      Q   AA +Q    +T+  QQQ  ++    +LA  
Sbjct: 73   AAQYL---------------------QQMYAAQQQHLMLHTAALQQQHLSSSQLQSLAAV 111

Query: 109  SAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQL-----GNLLQVNR 163
             A+  +S  +  +SP+ +   QS +   + +   + + AQ+  R Q      G++ Q   
Sbjct: 112  QAS--LSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTM 169

Query: 164  TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ 223
             LG   P  +                            A Q Q + +R Q          
Sbjct: 170  LLGSTSPTLT----------------------------ASQAQ-MYLRAQMLIFTPATTV 200

Query: 224  GSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGG 283
             + Q  IP     VSS S +S Q+ A    +    +Q L                     
Sbjct: 201  AAVQSDIPV----VSSSSSSSCQSAATQVQNLTLRSQKL--------------------- 235

Query: 284  GGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQ---TVTVSQGSQTEAESAAAKKAE 340
                    G L SS  G    P K T   Q L       TVT S+ SQ +    + KK E
Sbjct: 236  --------GVLSSSQNG----PPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGE 283

Query: 341  ADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQ-QIHLQQKQVVIQQQI 399
            +     ++  +  TRT++      LI+ A+Y+ IQPHSLI+ QQ  +H    +V   Q I
Sbjct: 284  SPSLESRSTAV--TRTSS---IHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLI 338

Query: 400  AIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQ-Q 458
                QQQ Q  Q   L  +T      Q     Q       P         P Q  P+   
Sbjct: 339  L---QQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLT 395

Query: 459  VPPSQSQQQAQTLVVQPMLQSSPLSLP-----PDAAPKP-PIPIQSKPPVAPIKPPQLGA 512
            V P+QSQ   Q++VV P    SP   P     P A  +P P+   +  P   ++      
Sbjct: 396  VSPNQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQ 455

Query: 513  AKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASS 572
             + +A    P H+P+        G  Q  AL ++     V  S     ++QS    +AS 
Sbjct: 456  VQATAQLNLPSHLPLPASPVVHIGPVQQSAL-VSPGQQIVSPSHQQYSSLQSSPIPIASP 514

Query: 573  PPSSQAPGALQECPPTLAPGMTLAPVQ----GTAHVVKGGATTSSPVVAQVPAAFYMQSV 628
            P  S +P A  + PP     M    VQ        V+   A  S   +    A   +   
Sbjct: 515  PQMSTSPPA--QIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQ 572

Query: 629  HLPGKPQTLAVKRKADS----------------EEERDDVSTLGSMLPAKASPVAESPKV 672
             LP  PQT+AV  +                   EEE  + S     +     P   SP  
Sbjct: 573  TLP-PPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSPAA 631

Query: 673  --------MDEKSSLGEKAE--SVANVNAN---TPSSELVALTPAPSV--PPPTLAMVSR 717
                    +  +  L E+ E  +VA+V+A+   +PS       P P +  P  T    S 
Sbjct: 632  ITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNST 691

Query: 718  QMGDS------KPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKES---EKPL--- 765
             M  S      KPPQAIVKPQILTH+IEGFVIQEG EPFPV  S LL E    ++PL   
Sbjct: 692  SMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDN 751

Query: 766  --------QTGLPTGLTENQSGGPLGVDSPSAEL---DKKANLLKCEYCGKYAPAEQFRG 814
                    Q  L        +     ++   AE    +  + LLKCE+CGK   A +F  
Sbjct: 752  QVINSVCVQPELQNNTKHADNSSDTEMEDMIAEETLEEMDSELLKCEFCGKMGYANEFLR 811

Query: 815  SKRFCSMTCAKRYNVSCSHQFRLKRKKMKEFQEANYARVRR-RGPRRSSSDIARAKIQGK 873
            SKRFC+M+CAKRYNVSCS +F L R   K   ++   R RR  GP  ++ +    ++   
Sbjct: 812  SKRFCTMSCAKRYNVSCSKKFALSRWNRKPDNQSLGHRGRRPSGPDGAAREHILRQLPIT 871

Query: 874  CHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHG-----ERDLGNPNTAPPTPELHGI 928
                +ED +   D+           P  ++ R         ER+L +       PE   +
Sbjct: 872  YPSAEEDLASHEDSV----------PSAMTTRLRRQSERERERELRDVRIRK-MPENSDL 920

Query: 929  NPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKL 988
             PV   + PS W+V++V+ FI SL GCQ+IA+EFR+QEIDGQALLLLKE+HLMSAMNIKL
Sbjct: 921  LPV-AQTEPSIWTVDDVWAFIHSLPGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKL 979

Query: 989  GPALKICAKINVLKET 1004
            GPALKICA+IN LKE+
Sbjct: 980  GPALKICARINSLKES 995


>gi|37595530 polyhomeotic-like 2 isoform b [Homo sapiens]
          Length = 323

 Score =  257 bits (657), Expect = 3e-68
 Identities = 158/318 (49%), Positives = 200/318 (62%), Gaps = 29/318 (9%)

Query: 711  TLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLL------KESEKP 764
            ++A  + Q G++KPPQAIVKPQILTH+IEGFVIQEGAEPFPVG S LL      K ++  
Sbjct: 11   SIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGF 70

Query: 765  LQTGLP----TGLTENQSGGPLGVDSPSAELDKKANLLKCEYCGKYAPAEQFRGSKRFCS 820
            L   LP    T  T+++   P   +S       K   LKCE CG+   A +F+ SKRFCS
Sbjct: 71   LPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLK---LKCELCGRVDFAYKFKRSKRFCS 127

Query: 821  MTCAKRYNVSCSHQFRLKRKKMKEFQEANYARVRRRGPRRSS----SDIARAKIQG---- 872
            M CAKRYNV C+ +  L      + Q+A  A   RR   ++S    +   + +  G    
Sbjct: 128  MACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPL 187

Query: 873  ------KCHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGERDLGNPNTAPPTPELH 926
                  +    QEDSSR SDNSSY+E LSP S    + R   G+RDL  P+      +L 
Sbjct: 188  SVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMH--MRDLV 245

Query: 927  GINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNI 986
            G+   FL S P++W+VE+VYEFI SL GCQEIAEEFR+QEIDGQALLLLKE+HLMSAMNI
Sbjct: 246  GMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNI 305

Query: 987  KLGPALKICAKINVLKET 1004
            KLGPALKI A+I++LK++
Sbjct: 306  KLGPALKIYARISMLKDS 323


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score =  126 bits (317), Expect = 9e-29
 Identities = 139/514 (27%), Positives = 206/514 (40%), Gaps = 89/514 (17%)

Query: 260 QSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSG--MGGGSCPRKGTGVVQPLPA 317
           QSL    A G +G  +P    P G GQ+ GG+G L + G  M     P  GT  + P   
Sbjct: 86  QSLTGGPAAGAAGIGMP----PRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSM 141

Query: 318 AQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPH 377
           A   T +  +Q + +  A ++ +     QQ     L +       Q   +  +  Q Q  
Sbjct: 142 AVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQ 201

Query: 378 SLIQQQQQIHLQQKQVVIQQQIAIHHQ--QQFQHRQSQLLHTATHLQLAQQQQQQQQQQQ 435
           +++QQQQQ+  QQ+Q   Q  I +HHQ  QQ Q +Q QL   A      QQQQQQQQQQQ
Sbjct: 202 AVVQQQQQLQQQQQQQ--QHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQ 259

Query: 436 QQQQPQA-TTLTAP--QPPQVPPTQQVPPSQSQQQAQTLVVQ--------PMLQSSPLSL 484
           QQQ  QA   +  P  Q PQ PP+Q + P Q QQ   T   Q        P+ Q+ P  L
Sbjct: 260 QQQALQAQPPIQQPPMQQPQPPPSQAL-PQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318

Query: 485 PPDAAPKPPIP---------IQSKPPVAPIKPPQLGAAKMSAAQQPP--PHIPVQVVGTR 533
           PP +  +P +          + ++PP+  ++ P +        QQPP  P +  Q    +
Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV-------VQQPPVQPQVQQQQTAVQ 371

Query: 534 QPGTAQAQALGLAQLAAAVP------------TSRGMPGTVQ-SGQAHLASSPPSSQAPG 580
               AQ  A G+    +++P            T + MP   Q S Q    SS P+S    
Sbjct: 372 TAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSS 431

Query: 581 ALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQS---VHLPGKPQTL 637
                P +  P  +  P Q             SPV A+ P  F + S   ++ P  P ++
Sbjct: 432 GPAPSPSSFLPSPSPQPSQ-------------SPVTARTPQNFSVPSPGPLNTPVNPSSV 478

Query: 638 ---AVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGE------------- 681
              A   +A+ ++  D +  L   +      + +  K  D K  L +             
Sbjct: 479 MSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSK 538

Query: 682 ----KAESVANVNANTPSSELVALTPAPSVPPPT 711
               K      +      +++   TP P   PPT
Sbjct: 539 RCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPT 572



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 98/445 (22%), Positives = 150/445 (33%), Gaps = 52/445 (11%)

Query: 25  QIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQA 84
           Q  Q +L ++Q  Q  Q  Q Q +A Q   Q ++QQQ    QL      QQ  I    Q 
Sbjct: 171 QQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQ---QQLQQQQQQQQHLIKLHHQ- 226

Query: 85  SSPNTSTTQQQTTTTQ--ASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPL 142
              N    QQQ    Q  A + L      Q   + Q   +  A    Q   +     PP 
Sbjct: 227 ---NQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP- 282

Query: 143 NQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADA 202
             SQA     PQ   L Q++ T     P        P      V Q  PS   P      
Sbjct: 283 --SQAL----PQ--QLQQMHHTQHHQPP--------PQPQQPPVAQNQPSQLPPQSQTQP 326

Query: 203 DQVQNLAVRNQQASAQGP-QMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQS 261
              Q  A+  Q    Q P +   +      P   P     Q + Q    AQ  +     S
Sbjct: 327 LVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS 386

Query: 262 LN----LSQAGGGSGNSIPGSMGPGGGGQAHGGL-GQLPSSGMGGGSCPRKGTGVVQPLP 316
            +    LS    G     P SM P        G     P+S +  G  P   + +  P P
Sbjct: 387 QSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSP 446

Query: 317 AAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQP 376
                   Q SQ+   +   +       G  N  +N +   +PA S         +Q + 
Sbjct: 447 --------QPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS---------SQAEE 489

Query: 377 HSLIQQQQQI--HLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH-LQLAQQQQQQQQQ 433
              + + +Q+  +++  + +I +      +++   +   LL   T   +    +  Q+ +
Sbjct: 490 QQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCE 549

Query: 434 QQQQQQPQATTLTAPQPPQVPPTQQ 458
              ++      +  P PP VPPT+Q
Sbjct: 550 IALEKLKNDMAVPTPPPPPVPPTKQ 574


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score =  123 bits (309), Expect = 8e-28
 Identities = 142/541 (26%), Positives = 215/541 (39%), Gaps = 103/541 (19%)

Query: 260 QSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSG--MGGGSCPRKGTGVVQPLPA 317
           QSL    A G +G  +P    P G GQ+ GG+G L + G  M     P  GT  + P   
Sbjct: 86  QSLTGGPAAGAAGIGMP----PRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSM 141

Query: 318 AQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPH 377
           A   T +  +Q + +  A ++ +     QQ     L +       Q   +  +  Q Q  
Sbjct: 142 AVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQ 201

Query: 378 SLIQQQQQIHLQQKQVVIQQQIAIHHQ--QQFQHRQSQLLHTATHLQLAQQQQQQQQQQQ 435
           +++QQQQQ+  QQ+Q   Q  I +HHQ  QQ Q +Q QL   A      QQQQQQQQQQQ
Sbjct: 202 AVVQQQQQLQQQQQQQ--QHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQ 259

Query: 436 QQQQPQA-TTLTAP--QPPQVPPTQQVPPSQSQQQAQTLVVQ--------PMLQSSPLSL 484
           QQQ  QA   +  P  Q PQ PP+Q + P Q QQ   T   Q        P+ Q+ P  L
Sbjct: 260 QQQALQAQPPIQQPPMQQPQPPPSQAL-PQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQL 318

Query: 485 PPDAAPKPPIP---------IQSKPPVAPIKPPQLGAAKMSAAQQPP--PHIPVQVVGTR 533
           PP +  +P +          + ++PP+  ++ P +        QQPP  P +  Q    +
Sbjct: 319 PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMV-------VQQPPVQPQVQQQQTAVQ 371

Query: 534 QPGTAQAQALGLAQL--------------------AAAVPTSRGMPGTVQSGQAHLASSP 573
               AQ  A G+  +                     +A+P+S    G     Q   +S P
Sbjct: 372 TAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLP 431

Query: 574 P-SSQAPGALQECPPTLAPGMTLAPVQG------TAHVVKGGA-------------TTSS 613
             SS +PG   + P ++ P    +P  G       ++V  G A              + S
Sbjct: 432 MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 491

Query: 614 PVVAQVPAAFYMQS---VHLPGKPQTL---AVKRKADSEEERDDVSTLGSMLPAKASPVA 667
           PV A+ P  F + S   ++ P  P ++   A   +A+ ++  D +  L   +      + 
Sbjct: 492 PVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYIEPLRRMIN 551

Query: 668 ESPKVMDEKSSLGE-----------------KAESVANVNANTPSSELVALTPAPSVPPP 710
           +  K  D K  L +                 K      +      +++   TP P   PP
Sbjct: 552 KIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPP 611

Query: 711 T 711
           T
Sbjct: 612 T 612



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 101/469 (21%), Positives = 163/469 (34%), Gaps = 60/469 (12%)

Query: 25  QIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQA 84
           Q  Q +L ++Q  Q  Q  Q Q +A Q   Q ++QQQ    QL      QQ  I    Q 
Sbjct: 171 QQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQ---QQLQQQQQQQQHLIKLHHQ- 226

Query: 85  SSPNTSTTQQQTTTTQ--ASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPP- 141
              N    QQQ    Q  A + L      Q   + Q   +  A    Q   +     PP 
Sbjct: 227 ---NQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPS 283

Query: 142 --LNQSQAQMYL--------RPQLGNLLQVNRTL----GRNVPLASQLILMPNGAVAAVQ 187
             L Q   QM+         +PQ   + Q   +      +  PL SQ   +P G +   Q
Sbjct: 284 QALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALP-GQMLYTQ 342

Query: 188 QEVPSA------QSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGAS------ 235
             +         Q P V     Q Q      Q A    P +Q  T+     G        
Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFP 402

Query: 236 PVSSLSQASSQALAVAQASSGATNQSL--NLSQAGGGSGNSIPGSMGPGGGGQAHGGL-G 292
           P +++S   S ++ + +      +QS    LS    G     P SM P        G   
Sbjct: 403 PTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPS 462

Query: 293 QLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMN 352
             P+S +  G  P   + +  P P        Q SQ+   +   +       G  N  +N
Sbjct: 463 SQPNSNVSSGPAPSPSSFLPSPSP--------QPSQSPVTARTPQNFSVPSPGPLNTPVN 514

Query: 353 LTRTATPAPSQTLISSATYTQIQPHSLIQQQQQI--HLQQKQVVIQQQIAIHHQQQFQHR 410
            +   +PA S         +Q +    + + +Q+  +++  + +I +      +++   +
Sbjct: 515 PSSVMSPAGS---------SQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSK 565

Query: 411 QSQLLHTATH-LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQ 458
              LL   T   +    +  Q+ +   ++      +  P PP VPPT+Q
Sbjct: 566 MKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQ 614


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 158/628 (25%), Positives = 229/628 (36%), Gaps = 88/628 (14%)

Query: 213  QQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATN--QSLNLSQAGGG 270
            QQ   QGP +Q  T +A+ P   P   +  +S Q L V Q S       Q +        
Sbjct: 3754 QQQQQQGPGVQ--TNQALGP--KPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAV 3809

Query: 271  SGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTE 330
                 PG++GP G    H  +    S  +      ++G G++      + VT  Q  Q +
Sbjct: 3810 LQQQHPGALGPQG---PHRQVLMTQSRVLSSPQLAQQGQGLM----GHRLVTAQQQQQQQ 3862

Query: 331  AESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQ 390
                    A      Q  +  +     +  P  +L       Q+Q    +QQQQQ  LQQ
Sbjct: 3863 QHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQ 3922

Query: 391  KQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQP 450
            +Q + QQQ+    QQQ   +Q Q        QL QQQQQQQQQ QQQQQ Q   L     
Sbjct: 3923 QQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLL---- 3978

Query: 451  PQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQL 510
                            Q++TL+     Q   ++L P    KP     S   + P      
Sbjct: 3979 ---------------NQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGP------ 4017

Query: 511  GAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLA 570
                ++  +Q      V    T  P T Q   L +     ++ T  G      SG + L 
Sbjct: 4018 -TLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLL 4076

Query: 571  SSPPSSQ-APGALQECPPTLAPGMTLAPVQGTAHVVKGGA-----TTSSPVVAQVPAAFY 624
               P  Q  P +LQ  PP   PG     V    H   GG+     + SS   + VP    
Sbjct: 4077 LVQPQPQPQPSSLQLQPPLRLPGQQQQQV-SLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135

Query: 625  MQSVHLPGKPQTLAVKRKADSEE--ERDDVSTLGSMLPAKASPVAESPKVMDE---KSSL 679
              SV L  +P ++        +   ER   +  G   P K  PV +S + +       ++
Sbjct: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQ-PPKPGPVLQSGQGLPGVGIMPTV 4194

Query: 680  GEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMGDSK-----PPQAIVKPQIL 734
            G+    +  V A  P  +L  L+P        L M  RQ+  S+     PP    +P   
Sbjct: 4195 GQLRAQLQGVLAKNP--QLRHLSPQQQQQLQALLM-QRQLQQSQAVRQTPPYQ--EPGTQ 4249

Query: 735  THIIEGFV----------------IQE-GAEPFPVGCSQLLKESEKPLQTG--------L 769
            T  ++G +                +QE GA P P G  + L      L TG         
Sbjct: 4250 TSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPR-LPAPPGALSTGPVLGPVHPT 4308

Query: 770  PTGLTENQSGGPLGVDSPSAELDKKANL 797
            P   +  +   P  + SPS++L  +A L
Sbjct: 4309 PPPSSPQEPKRPSQLPSPSSQLPTEAQL 4336



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 161/712 (22%), Positives = 238/712 (33%), Gaps = 95/712 (13%)

Query: 21   SSRPQIAQMSLYERQAVQALQALQRQPN-AAQYFHQFMLQQQLSNAQLHSLAAVQQATIA 79
            S +P+++   +   Q +Q  Q LQ+Q     Q   Q   QQQL   QL      QQ    
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943

Query: 80   ASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTS 139
              +Q         QQQ    Q            L+++S+++ SP      Q  L     +
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPA 4003

Query: 140  PPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVH 199
             PL    +   L P L    +   T+              + AV++   E PS    G  
Sbjct: 4004 KPLQHFSSPGALGPTLLLTGKEQNTV--------------DPAVSSEATEGPSTHQGGPL 4049

Query: 200  ADADQVQNLAVRNQQASAQGPQMQGSTQ-KAIPPGASPVSSLSQASSQALAVAQASSGAT 258
            A     +++A    +     P + G +Q   + P   P     Q SS  L       G  
Sbjct: 4050 AIGTTPESMATEPGEVK---PSLSGDSQLLLVQPQPQP-----QPSSLQLQPPLRLPGQQ 4101

Query: 259  NQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAA 318
             Q ++L    GG  +   G +G G   +A      L    +  G  P   T   Q L   
Sbjct: 4102 QQQVSLLHTAGGGSH---GQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT---QNLLGP 4155

Query: 319  QTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHS 378
            Q   + +  Q        K      SGQ   G+ +  T     +Q     A   Q++ H 
Sbjct: 4156 QQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLR-HL 4214

Query: 379  LIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQ 438
              QQQQQ+     Q  +QQ  A+     +Q   +Q     + LQ     Q Q       Q
Sbjct: 4215 SPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQ----TSPLQGLLGCQPQLGGFPGPQ 4270

Query: 439  QPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQS 498
                  L A   PQ PP    PP               L + P+  P    P P  P   
Sbjct: 4271 TGPLQELGAGPRPQGPPRLPAPPG-------------ALSTGPVLGPVHPTPPPSSP--- 4314

Query: 499  KPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGM 558
            + P  P + P   +   + AQ PP H          PGT + Q           PT    
Sbjct: 4315 QEPKRPSQLPSPSSQLPTEAQLPPTH----------PGTPKPQG----------PTLEPP 4354

Query: 559  PGTVQSGQAHLASS----------PPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGG 608
            PG V    A LA +          PP + A     E   +L PG  L  V G   V +  
Sbjct: 4355 PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE-QSSLVPG-HLDQVNGQV-VPEAS 4411

Query: 609  ATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAE 668
              +      + P A   QSV      + +     ++        S  G +L  K    A+
Sbjct: 4412 QLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLR-AK 4470

Query: 669  SPKVMDEKSSLGEKAESVANVNA----------NTPSSELVALTPAPSVPPP 710
            + ++   + S G +AE   ++++           TPS++  A    P  P P
Sbjct: 4471 NVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKP 4522



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 72/291 (24%), Positives = 110/291 (37%), Gaps = 40/291 (13%)

Query: 275  IPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESA 334
            +PG + PG G Q   G    P  G  GG     G   +   P    +  +   Q + + +
Sbjct: 3631 LPGQLLPGHGLQPPQG----PPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHS 3686

Query: 335  AAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVV 394
                + A  SG    G    R+                 + P S + Q++Q+ LQQ+++ 
Sbjct: 3687 GGAGSLAGPSGGFFPGNLALRS-----------------LGPDSRLLQERQLQLQQQRMQ 3729

Query: 395  IQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQ---QQQQQQQQPQATTLTAPQPP 451
            + Q++    QQQ Q +Q  LL      Q+A QQQQQQ    Q  Q   P+   L  P   
Sbjct: 3730 LAQKL--QQQQQQQQQQQHLLG-----QVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSH 3782

Query: 452  QVPPTQQV---PPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPP 508
            Q    QQ+   PP   Q       V  + Q  P +L P    +  +  QS+     +  P
Sbjct: 3783 QGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSR----VLSSP 3838

Query: 509  QLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMP 559
            QL  A+          +  Q    +Q    Q    GL+ L  ++ +  G P
Sbjct: 3839 QL--AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQP 3887



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 73/277 (26%), Positives = 98/277 (35%), Gaps = 64/277 (23%)

Query: 450  PPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQ 509
            PPQVP   QVP       A    ++P   ++P + PP  +P            AP +PP 
Sbjct: 2164 PPQVPA--QVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTG----------APAQPPM 2211

Query: 510  LGAAKMSAAQQP------PPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQ 563
            LGA+    A QP      PP  P     T  P   + +   L  L  AVP S G+ G   
Sbjct: 2212 LGASSRPGAGQPGEFHTTPPGTPRHQPSTPDP-FLKPRCPSLDNL--AVPESPGVGGGKA 2268

Query: 564  SGQAHLASSPPSSQAPGALQ-------ECPPTLAP---GMTLAPVQGTAHVVKGGATTSS 613
            S    L S PP  ++  AL+          P+  P   G   +P  GT H+  GG    +
Sbjct: 2269 S--EPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGT-HL--GGLELKT 2323

Query: 614  PVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVM 673
            P V + P                  +  +A   E +     L    P  A  +A SP   
Sbjct: 2324 PDVFKAP------------------LTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSH 2365

Query: 674  DEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPP 710
             +    G   +  A             LTP P  PPP
Sbjct: 2366 PDIFRPGSYTDPYAQ----------PPLTPRPQPPPP 2392



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 91/403 (22%), Positives = 142/403 (35%), Gaps = 52/403 (12%)

Query: 82   RQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLG------ 135
            +Q  S      QQQ    Q    L+    AQ +S     SSPS     Q + LG      
Sbjct: 3263 KQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQ 3322

Query: 136  -------NTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQ 188
                     T PP +  Q +  L P +  +      L        Q  L+P  +   V  
Sbjct: 3323 PGLPQPLMPTQPPAHALQQR--LAPSMAMVSNQGHMLSGQ--HGGQAGLVPQQSSQPVLS 3378

Query: 189  EVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQAL 248
            + P    P   +   + Q LA++ Q A++  P      + A      P++     + + +
Sbjct: 3379 QKPMGTMP--PSMCMKPQQLAMQQQLANSFFPDTD-LDKFAAEDIIDPIAKAKMVALKGI 3435

Query: 249  --AVAQASSGAT------NQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG 300
               +AQ S G          SL   +  GG  + +   +  G G +   G    P     
Sbjct: 3436 KKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRP--- 3492

Query: 301  GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA 360
              + P    GV+      Q       +Q   +       E  G  ++      +R A  A
Sbjct: 3493 --NPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRK------SRKALCA 3544

Query: 361  PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH 420
              +T   +            ++  +   ++ ++V +QQ  I  Q   Q R+ Q  HT   
Sbjct: 3545 KQRTAKKAG-----------REFPEADAEKLKLVTEQQSKIQKQLD-QVRKQQKEHTNLM 3592

Query: 421  LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQ 463
             +   +QQQQQQQQQQQQQ Q + + A  P Q P      P Q
Sbjct: 3593 AEYRNKQQQQQQQQQQQQQ-QHSAVLALSPSQSPRLLTKLPGQ 3634



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 88/383 (22%), Positives = 127/383 (33%), Gaps = 94/383 (24%)

Query: 187  QQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQ------GSTQKAIPPGASPVSSL 240
            QQ+     +PG      Q  +L       S  G Q Q      G+ Q  +P    P    
Sbjct: 3280 QQQHSLLSAPG----PAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPP 3335

Query: 241  SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG 300
            + A  Q LA + A    +NQ   LS   GG    +P          +   L Q P   M 
Sbjct: 3336 AHALQQRLAPSMAM--VSNQGHMLSGQHGGQAGLVPQQ-------SSQPVLSQKPMGTMP 3386

Query: 301  GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAA------------------KKAEAD 342
               C +      Q L   Q +  S    T+ +  AA                  KK  A 
Sbjct: 3387 PSMCMKP-----QQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQ 3441

Query: 343  GSGQQNVGMNLTRTATPA---------------------------PSQTLISSATYTQIQ 375
            GS     GMN  + +  A                           PSQ   +  T+ Q  
Sbjct: 3442 GSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGV 3501

Query: 376  PHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH--------------- 420
             +   Q+Q +  L   Q ++Q Q+ +  +Q   HR+S+    A                 
Sbjct: 3502 INEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADA 3561

Query: 421  --LQLAQQQQ---QQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQP 475
              L+L  +QQ   Q+Q  Q ++QQ + T L A    +    QQ    Q QQ +  L + P
Sbjct: 3562 EKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSP 3621

Query: 476  -----MLQSSPLSLPPDAAPKPP 493
                 +L   P  L P    +PP
Sbjct: 3622 SQSPRLLTKLPGQLLPGHGLQPP 3644



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 18/106 (16%)

Query: 440 PQATTLTAP--QPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQ 497
           P+A+ L+ P  + P  PP ++ P S   + ++     P  + SPLS PP+ +P  P P  
Sbjct: 567 PEASRLSPPPEESPMSPPPEESPMSPPPEASRLF---PPFEESPLSPPPEESPLSPPPEA 623

Query: 498 SK----PPVAPIKPPQLGAAKMSAAQQPPPHI----PVQVVGTRQP 535
           S+    P  +P+ PP        +   PPP +    P+ VV    P
Sbjct: 624 SRLSPPPEDSPMSPP-----PEESPMSPPPEVSRLSPLPVVSRLSP 664



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 95/394 (24%), Positives = 136/394 (34%), Gaps = 57/394 (14%)

Query: 440  PQATTLTAP--QPPQVPPTQQVP---PSQSQQQAQTLVVQPML------QSSPLSLPPDA 488
            P+A+ L+ P    P  PP +  P   P +    +  L   P+L      Q  P S  P  
Sbjct: 684  PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743

Query: 489  APKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPP--------PHIPVQVVGTR------- 533
            +P+P  P  S  P  P   PQ     +S   + P        PH+  Q  G         
Sbjct: 744  SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803

Query: 534  ---QPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECP---- 586
                P T +     + +     P       + QS +  L+  P  S     L++ P    
Sbjct: 804  LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR 863

Query: 587  ---PTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKA 643
               P   PG   AP +        G  + SP++ + PA        L   P+ L +    
Sbjct: 864  PEKPPEEPGQCPAPEE-LPLFPPPGEPSLSPLLGE-PALSEPGEPPLSPLPEELPLS--P 919

Query: 644  DSEEERDDVSTLGSMLPAKASPV--AESPKVMDEKSSLGEKAESVANVNANTPSSELVA- 700
              E            LP   SP+  A +P  +   S LGE          + P S L A 
Sbjct: 920  SGEPSLSPQLMPPDPLPPPLSPIITAAAPPAL---SPLGELEYPFGAKGDSDPESPLAAP 976

Query: 701  LTPAPSVPPPTLAMVSRQMGDSKP-PQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLK 759
            +   P  PPP          D +P P  I+ P   + +     I    EP P  CS LL+
Sbjct: 977  ILETPISPPP-----EANCTDPEPVPPMILPPSPGSPVGPASPIL--MEPLPPQCSPLLQ 1029

Query: 760  ESEKPLQTGLPTGLTENQSGGPLGVDSPSAELDK 793
             S  P Q   P+    +    PL V SP + + K
Sbjct: 1030 HSLVP-QNSPPSQC--SPPALPLSVPSPLSPIGK 1060



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 75/293 (25%), Positives = 117/293 (39%), Gaps = 44/293 (15%)

Query: 437 QQQPQATTLTAPQPPQVPPTQ--QVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPI 494
           Q QP+   +T+ QP +  P Q    P  ++  Q +  +  P+ +  PL  PP+ +P  P 
Sbjct: 393 QGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPP 452

Query: 495 PIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPT 554
           P +S  P +P  PP+  A+++S    PPP           P +   +AL L++     P 
Sbjct: 453 PEES--PTSP--PPE--ASRLS----PPPE--------ELPASPLPEALHLSRPLEESPL 494

Query: 555 SRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSP 614
           S   P   +S      S PP S     L+E P +       +P   T       A+  SP
Sbjct: 495 S---PPPEESP----LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP 547

Query: 615 VVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSML--PAKAS----PVAE 668
              + P +       LP  P   A +     EE         S +  P +AS    P  E
Sbjct: 548 PFEESPLS--PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605

Query: 669 SP-KVMDEKSSLGEKAESVANVNANTPSSELVALTP----APSVPPPTLAMVS 716
           SP     E+S L    E+    +  +P  E   ++P    +P  PPP ++ +S
Sbjct: 606 SPLSPPPEESPLSPPPEA----SRLSPPPEDSPMSPPPEESPMSPPPEVSRLS 654



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 56/200 (28%), Positives = 72/200 (36%), Gaps = 61/200 (30%)

Query: 402  HHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVP--PTQQV 459
            H +++ Q +Q          QL+ Q Q  QQQQQQQQ  Q + L+AP P Q    P +  
Sbjct: 3255 HEKKELQKKQ----------QLSAQLQPAQQQQQQQQ--QHSLLSAPGPAQAMSLPHEGS 3302

Query: 460  PPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQ 519
             PS +  Q Q            LSL    A +P +P     P+ P +PP           
Sbjct: 3303 SPSLAGSQQQ------------LSLGLAGARQPGLP----QPLMPTQPP----------- 3335

Query: 520  QPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAP 579
                              A A    LA   A V     M      GQA L   P  S  P
Sbjct: 3336 ------------------AHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLV--PQQSSQP 3375

Query: 580  GALQECPPTLAPGMTLAPVQ 599
               Q+   T+ P M + P Q
Sbjct: 3376 VLSQKPMGTMPPSMCMKPQQ 3395



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 63/308 (20%), Positives = 109/308 (35%), Gaps = 49/308 (15%)

Query: 440 PQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPI----- 494
           P+A+ L+ P P ++P +         +  +   + P  + SPLS PP+++P  P+     
Sbjct: 462 PEASRLSPP-PEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPL 520

Query: 495 -PIQSKPP----VAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLA 549
            P +  PP      P+ PP   +      ++ P   P + + T  P  A           
Sbjct: 521 SPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEA----------- 569

Query: 550 AAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPP----TLAPGMTLAPVQGTAHVV 605
                SR  P   +S  +      P S  P A +  PP     L+P    +P+       
Sbjct: 570 -----SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEAS 624

Query: 606 KGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASP 665
           +         ++  P    M       +   L V  +     E   +S      P + SP
Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP-----PPEESP 679

Query: 666 VAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQMGDSKPP 725
            +  P    E S L    E     +  +P  E      +P+ PPP  +++S  + +S   
Sbjct: 680 TSPPP----EASRLSPPPED----SPTSPPPE-----DSPASPPPEDSLMSLPLEESPLL 726

Query: 726 QAIVKPQI 733
               +PQ+
Sbjct: 727 PLPEEPQL 734



 Score = 37.4 bits (85), Expect = 0.071
 Identities = 43/175 (24%), Positives = 66/175 (37%), Gaps = 27/175 (15%)

Query: 434 QQQQQQPQATTLTAPQP---PQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAP 490
           ++    P   T  +P P   P  PP ++ P S   ++  T    P  ++S LS PP+ +P
Sbjct: 524 EESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT---SPPPEASRLSPPPEESP 580

Query: 491 KPPIPIQ---SKPPVA----------PIKPPQLGA-----AKMSAAQQPPPHIPVQVVGT 532
             P P +   S PP A          P+ PP   +      + S    PP   P+     
Sbjct: 581 MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE 640

Query: 533 RQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPP 587
             P +   +   L+ L      SR  P   +S  +      P+S  P A +  PP
Sbjct: 641 ESPMSPPPEVSRLSPLPV---VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692



 Score = 37.4 bits (85), Expect = 0.071
 Identities = 62/318 (19%), Positives = 109/318 (34%), Gaps = 75/318 (23%)

Query: 432 QQQQQQQQPQATTLTAP--QPPQVPPTQQVPPSQSQQQA------QTLVVQPMLQSSPLS 483
           ++      P+A+ L  P  + P  PP ++ P S   + +      +   + P  + SP+S
Sbjct: 586 EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS 645

Query: 484 LPPDAAPKPPIPIQSK----PPVAPIKPPQLGA-----AKMSAAQQPPPHIPVQVVGTRQ 534
            PP+ +   P+P+ S+    P  +P+ PP   +      + S    PP   P        
Sbjct: 646 PPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705

Query: 535 PGT------------AQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGAL 582
           P +             ++  L L +     P S G   + +  + HL+  P         
Sbjct: 706 PASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQA 765

Query: 583 QECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYM----QSVHLPGKPQTLA 638
           +E  P L+P                      P +  VP   ++    +  HL  +P+ L 
Sbjct: 766 EE--PHLSP------------------QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805

Query: 639 VKRKADSEEERDDVSTLGSMLPAKASPVAESP--KVMDEKSSLGEKAESVA-----NVNA 691
           +  + +                   SPV E P      E+S L  ++E          + 
Sbjct: 806 LSPQTEEPH---------------LSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH 850

Query: 692 NTPSSELVALTPAPSVPP 709
            +P  E   L+P P  PP
Sbjct: 851 LSPELEKPPLSPRPEKPP 868



 Score = 37.4 bits (85), Expect = 0.071
 Identities = 52/198 (26%), Positives = 78/198 (39%), Gaps = 47/198 (23%)

Query: 439  QPQATTLTAPQPPQ----VPPTQ-------QVPPS-QSQQQAQTLVVQPMLQS------- 479
            QP  T    P PP+    +PP         +VP S QSQ  +Q+ +    L +       
Sbjct: 2380 QPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP 2439

Query: 480  -SPLSLPPDAAPKPPIPIQSKPPVAPI-KPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGT 537
             +P    PD   +PP   QS+ P AP+ KPP          +  PP +  +       G+
Sbjct: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP----------RPQPPEVAFKA------GS 2483

Query: 538  AQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAP 597
                +LG     AA+P          +G+ H  +  PS Q P  ++  P T A   T +P
Sbjct: 2484 LAHTSLGAGGFPAALPAG-------PAGELH--AKVPSGQPPNFVRS-PGTGAFVGTPSP 2533

Query: 598  VQGTAHVVKGGATTSSPV 615
            ++ T     G  +   PV
Sbjct: 2534 MRFTFPQAVGEPSLKPPV 2551



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 115/587 (19%), Positives = 199/587 (33%), Gaps = 108/587 (18%)

Query: 408  QHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAP--QPPQVPPTQQVP--PSQ 463
            Q  +S L   +    L+ + ++     + ++ P +     P  +P Q P  +++P  P  
Sbjct: 827  QPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPP 886

Query: 464  SQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPP 523
             +     L+ +P L        P   P  P+P   + P++P   P L    M     PPP
Sbjct: 887  GEPSLSPLLGEPALSE------PGEPPLSPLP--EELPLSPSGEPSLSPQLMPPDPLPPP 938

Query: 524  HIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQ 583
              P+                    + AA P +    G ++        S P S     + 
Sbjct: 939  LSPI--------------------ITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPIL 978

Query: 584  ECP-----------PTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHLPG 632
            E P           P   P M L P  G+          +SP++ +            P 
Sbjct: 979  ETPISPPPEANCTDPEPVPPMILPPSPGSP------VGPASPILME------------PL 1020

Query: 633  KPQTLAVKRKA----DSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVAN 688
             PQ   + + +    +S   +     L   +P+  SP+ +   V DE      + E V+ 
Sbjct: 1021 PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVS- 1079

Query: 689  VNANTPSSELVALTPAPS----------VPPPTLAMVSRQMGDSKP----------PQAI 728
                 P+ E  A +P PS           P P L   S    D+ P          P+  
Sbjct: 1080 -EPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPG 1138

Query: 729  VKPQILTHIIEGF-VIQEGAEPFPVGCSQLLKESEKPLQTGLPTGLTENQSGGPLGVDSP 787
              P  L   ++G  V+ +  E  PV   ++  E ++    G P    + +   P+    P
Sbjct: 1139 QTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCE-EQEEPRAPVAPTPP 1197

Query: 788  ----SAELDKKANLLKCEYCGKYAPAEQFRGSK-----RFCSMTCAKRYNVSCSHQFRLK 838
                S  +++ +NL + +    +  +E   GS         SM      +VS +      
Sbjct: 1198 TLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSL 1257

Query: 839  RKKMKEFQEANYARVRRRGPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTS 898
            R       E + + +   G     + I+  K +G+  R +   +R    S   +  S + 
Sbjct: 1258 RLCTDSLPETDDSLLCDAG-----TAISGGKAEGEKGRRRSSPAR----SRIKQGRSSSF 1308

Query: 899  PGPLSVRAG-HGERDLGNPNTAPPTPELHGINPVFLSSNPSRWSVEE 944
            PG    R G HG R  G          +  +    + S+PS+   EE
Sbjct: 1309 PGRRRPRGGAHGGRGRGRARLKSTASSIETLVVADIDSSPSKEEEEE 1355


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 84.0 bits (206), Expect = 7e-16
 Identities = 145/611 (23%), Positives = 219/611 (35%), Gaps = 92/611 (15%)

Query: 220  PQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSM 279
            PQ Q   Q    P  +P  +    ++   A   A +  T+ +      G  SGN I  ++
Sbjct: 2543 PQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTI 2602

Query: 280  GPGGGGQAHGGLGQLPSSGMG-------GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAE 332
              G        + +  +S +        GGS P +      P  A  +   +        
Sbjct: 2603 A-GVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMA 2661

Query: 333  SAAAKKAEADGSGQQNVGMNLTRTATPAPSQT-LISSATYTQIQPHSLIQQQQQIHLQQK 391
            +    +A    +    V  NLT   TPA S    +S AT  Q+   ++     Q+  QQ+
Sbjct: 2662 TTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQ 2721

Query: 392  QVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPP 451
            Q   QQQ     QQQ                  QQQQQQQQQQQQQQQ Q TT +  Q P
Sbjct: 2722 QQQQQQQ-----QQQ------------------QQQQQQQQQQQQQQQ-QTTTTSQVQVP 2757

Query: 452  QVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLG 511
            Q+         Q+Q  AQ   V  +     + +       PP   Q  PP A   PPQ  
Sbjct: 2758 QI-------QGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPP---QPPPPQAQSAPPQPT 2807

Query: 512  AAKMSAAQQPPPHIPVQVVGTRQP-------GTAQAQALGLAQLAAAVPTS----RGMPG 560
            A       QPP     Q+     P       GT  A  L +A+L   VPTS    +G   
Sbjct: 2808 AQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVAN-LQVARL-TRVPTSQLQAQGQMQ 2865

Query: 561  TVQSGQAHLA-SSPPSSQAPGALQECPPTLAPGMTLAPVQ---GTAHVVKGGATTSSPVV 616
            T     A +A + PP    P A+   P      M +A +    G      G    + PV 
Sbjct: 2866 TQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVH 2925

Query: 617  AQVPAAFYMQSVHLPGKPQTLAVKRKADSEEE--RDDVSTLGSM-------LPAKASPVA 667
             Q       Q+V      Q  A +  A  +++     ++T G+         PA  +   
Sbjct: 2926 MQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFL 2985

Query: 668  ESPKVMDEKSSLGEKAESVAN-------VNANTPSSELVALTPAPSVPPPTLAMVSRQMG 720
             +P    +K +  ++ ++          V   TP + +  +  A     P    +++   
Sbjct: 2986 TTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQQASPQTVALTQATA 3045

Query: 721  DSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQLLKESEKPLQT-GLPTGLTENQSG 779
              +  Q I        +++  +IQ+          Q++  +  PLQT G P     N + 
Sbjct: 3046 AGQQVQMIPAVTATAQVVQQKLIQQ----------QVVTTASAPLQTPGAP-----NPAQ 3090

Query: 780  GPLGVDSPSAE 790
             P   DSPS +
Sbjct: 3091 VPASSDSPSQQ 3101



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 83/353 (23%), Positives = 123/353 (34%), Gaps = 55/353 (15%)

Query: 426  QQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLP 485
            ++++    QQ+ QQP       PQP   PP QQ PP   Q QA          S P + P
Sbjct: 2487 KEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQA--------AGSQPPAGP 2538

Query: 486  PDAAPKPPIPIQSKP-PVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALG 544
            P   P+P    Q++P PV      Q       +A      I   V GT  P T       
Sbjct: 2539 PAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMP-TGAVSGNV 2597

Query: 545  LAQLAAAVP-----------TSRGMPGTVQ----SGQAHLASSPPSSQAPGALQECPPTL 589
            +    A VP            S   PG +     S  A +  + P  +A G+     P L
Sbjct: 2598 IVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDL 2657

Query: 590  APGMTLAPVQGTAHVVKGGATTS------SPVVAQVPAAFYMQSVHLPGKP------QTL 637
                T   V+    V      T+      +P  + VP       V LPGK       Q L
Sbjct: 2658 VSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLL 2717

Query: 638  AVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNA---NTP 694
              +++   ++++            +      +     +   +  +A+S A + A    TP
Sbjct: 2718 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTP 2777

Query: 695  ------SSELVALTPAP------SVPPPTLAMVSRQMGDSKPPQAIVKPQILT 735
                    + + + P P      S PP   A V  Q+  S+PPQ    PQ+ T
Sbjct: 2778 EHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQV--QVQTSQPPQQ-QSPQLTT 2827



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 87/331 (26%), Positives = 120/331 (36%), Gaps = 41/331 (12%)

Query: 214 QASAQGPQMQGSTQKAIP-PGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSG 272
           Q S   P  +G  Q A P P  SP +  + ++S +    Q+ S    Q +N S A G + 
Sbjct: 15  QRSRACPGSEGEEQPAHPNPPPSPAAPFAPSASPS--APQSPSYQIQQLMNRSPATGQNV 72

Query: 273 NSIPGSMGPGGGGQAHGGLGQLP-----SSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGS 327
           N    S+GP  GG     L  LP     S G    + PR+        P+   VT     
Sbjct: 73  NITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRR---FEHGSPSYIQVTSPLSQ 129

Query: 328 QTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSA-TYTQIQPHSLIQQQQQI 386
           Q + +S   + +   G   QNV     R   P P   L SS+ T   +    L++Q    
Sbjct: 130 QVQTQS-PTQPSPGPGQALQNV-----RAGAPGPGLGLCSSSPTGGFVDASVLVRQISLS 183

Query: 387 HLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQ-------QQQQ 439
                  V Q    +   Q  Q  Q QL H  T + + +++  Q   Q          Q 
Sbjct: 184 PSSGGHFVFQDGSGL--TQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQS 241

Query: 440 PQATTLTAPQP---PQVPPTQQVPPS-QSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIP 495
           P A      QP   P    T  +PP   S  Q Q +  Q +LQ  PL          P P
Sbjct: 242 PAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQVLQGPPL----------PRP 291

Query: 496 IQSKPPVAPIKPPQLGAAKMSAAQQPPPHIP 526
           +  +     + P   GAA       PPP  P
Sbjct: 292 LGFERTPGVLLPGAGGAAGFGMTSPPPPTSP 322



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 61/232 (26%), Positives = 89/232 (38%), Gaps = 31/232 (13%)

Query: 404 QQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQP-PQVPPTQQVPPS 462
           QQ     Q  +  T    QLA Q+Q QQQ       P     +   P PQ+P   ++PP+
Sbjct: 506 QQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPG--RLPPA 563

Query: 463 QSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQP- 521
                  T  +   LQ +      +A  +  IP++++ P  PI  P        ++Q P 
Sbjct: 564 G----VPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAP-------PSSQLPI 612

Query: 522 PPHIPVQV-VGTRQPGTAQAQALGLAQLAAAV-----------PTSRGMPGTVQSGQAHL 569
           PP  P Q+ +    PG  Q QA  L+ L   V           P  R +P +  S  A +
Sbjct: 613 PPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPV 672

Query: 570 ASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPA 621
           + S P      +     P+ A    L+PV         G   S+P   Q PA
Sbjct: 673 SGSGPGPSPARSSPVNRPSSATNKALSPVTSRT----PGVVASAPTKPQSPA 720



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 111/465 (23%), Positives = 155/465 (33%), Gaps = 85/465 (18%)

Query: 55   QFMLQQQLSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLI 114
            Q + QQQ    Q       QQ      +Q     T+T+Q Q    Q        S AQ+ 
Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQ----AQSPAQI- 2769

Query: 115  SRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQ 174
             ++    +P      Q   L     PP  Q+Q+     PQ    +QV      + P   Q
Sbjct: 2770 -KAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQS---APPQPTAQVQVQ----TSQPPQQQ 2821

Query: 175  LILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAV-RNQQASAQGPQMQGSTQKAIPPG 233
                      + Q    +A  PG       V NL V R  +      Q QG  Q   P  
Sbjct: 2822 ----------SPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQP 2871

Query: 234  ASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQ 293
            A    +     S   AV  +S G T   +N+      +G S+         GQ     GQ
Sbjct: 2872 AQVALAKPPVVSVPAAVV-SSPGVTTLPMNV------AGISV-------AIGQPQKAAGQ 2917

Query: 294  LPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNL 353
                           T V QP+   Q + + Q +  + ++   + A+   + QQ +    
Sbjct: 2918 ---------------TVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKI--TA 2960

Query: 354  TRTATPAPSQ-----------TLISSATYTQIQPHSLIQQ-QQQIHLQQKQVVIQQQIAI 401
             +  TP   Q           T   +   +Q Q  +  QQ Q QI + +   V+QQQ  +
Sbjct: 2961 QQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPV 3020

Query: 402  HHQQQFQHRQSQLLHTATHLQLAQQQQQQQQ------------QQQQQQQPQATTLTAP- 448
               QQ      Q       L  A    QQ Q            QQ+  QQ   TT +AP 
Sbjct: 3021 ASIQQVASASQQASPQTVALTQATAAGQQVQMIPAVTATAQVVQQKLIQQQVVTTASAPL 3080

Query: 449  QPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPP 493
            Q P  P   QVP S           QP LQ    ++      KPP
Sbjct: 3081 QTPGAPNPAQVPASSDSPSQ-----QPKLQMRVPAVRLKTPTKPP 3120



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 47/179 (26%), Positives = 68/179 (37%), Gaps = 16/179 (8%)

Query: 421 LQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQ--VPPSQSQQQAQTLVV--QPM 476
           LQ AQQ Q  + Q Q Q   +      P P   PP+ Q  +PPSQ  Q A  +    +  
Sbjct: 574 LQFAQQPQVVEAQTQLQIPVKTQQPNVPIP--APPSSQLPIPPSQPAQLALHVPTPGKVQ 631

Query: 477 LQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPG 536
           +Q+S LS  P       +P+   PP     P    ++    +   P   P +     +P 
Sbjct: 632 VQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPS 691

Query: 537 TAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTL 595
           +A  +AL         P +   PG V S  A      P+  A  +      TL   +TL
Sbjct: 692 SATNKALS--------PVTSRTPGVVAS--APTKPQSPAQNATSSQDSSQDTLTEQITL 740



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 47/179 (26%), Positives = 64/179 (35%), Gaps = 27/179 (15%)

Query: 473 VQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGT 532
           VQ  LQ S      +   +P  P     P AP  P    +A  SA Q P   I  Q +  
Sbjct: 10  VQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAP----SASPSAPQSPSYQI--QQLMN 63

Query: 533 RQPGTAQA---------------QALGLAQLAAAVPTSRGMPGTVQ------SGQAHLAS 571
           R P T Q                Q + LA L    PTS G   + Q         +++  
Sbjct: 64  RSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQFSAQPRRFEHGSPSYIQV 123

Query: 572 SPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHL 630
           + P SQ         P+  PG  L  V+  A     G  +SSP    V A+  ++ + L
Sbjct: 124 TSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQISL 182



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 47/173 (27%), Positives = 69/173 (39%), Gaps = 20/173 (11%)

Query: 424  AQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLS 483
            AQ   Q     Q   QPQA +  A Q     P + V PSQ+Q +  +  V  + Q + ++
Sbjct: 1519 AQTTAQASTPGQPPPQPQAPSHAAGQ--SALPQRLVLPSQAQARLPSGEVVKIAQLASIT 1576

Query: 484  LPPD--AAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQ 541
             P    A P+ P+ +Q +     +   QL   +++A Q      P+Q+ G+         
Sbjct: 1577 GPQSRVAQPETPVTLQFQGSKFTLSHSQL--RQLTAGQ------PLQLQGS---VLQIVS 1625

Query: 542  ALGLAQLAAAVPTSRGMPGTVQSGQAH--LASSPPSSQAPGALQECPPTLAPG 592
            A G   L A  P    M    Q+G  H  L S PP+   P      P    PG
Sbjct: 1626 APGQPYLRAPGPVV--MQTVSQAGAVHGALGSKPPAG-GPSPAPLTPQVGVPG 1675


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 166/723 (22%), Positives = 249/723 (34%), Gaps = 77/723 (10%)

Query: 14  GSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAV 73
           G  SS G   P  +  +     A    Q   R P+A       +  QQ    Q   LAA+
Sbjct: 125 GGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAAL 184

Query: 74  QQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVL 133
           Q          + P  ++        Q +      SA    + + ++SSP   T      
Sbjct: 185 QSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAA 244

Query: 134 LGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSA 193
               + PP + S +            Q    +G   P A+        A   + Q + S 
Sbjct: 245 AAAGSKPPPSSSASASSSSSSFAQ--QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSP 302

Query: 194 QSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQA 253
            S               R  Q    G    G        G + ++S    ++ A A A A
Sbjct: 303 SS--------------ARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAA 348

Query: 254 SSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQ 313
           +SG   Q  + +    GS          GGGGQ    L + P       S P    G ++
Sbjct: 349 ASGGAQQRSHHAPMSPGSS---------GGGGQP---LARTPQP-----SSPMDQMGKMR 391

Query: 314 PLPAAQTVTVSQ--GSQTEAESAAAKKAEADGSGQ-QNVGMNLTRTATPAPSQTLISSAT 370
           P P   T   SQ  G  +  +       +  GS   Q   M +   A     Q+ +   +
Sbjct: 392 PQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA-----QSAMGGLS 446

Query: 371 YTQ-IQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQ 429
           YTQ I P+   QQ    + QQ Q     Q + H QQQ      Q      H Q + QQQ 
Sbjct: 447 YTQQIPPYG--QQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQP 504

Query: 430 QQQQQQ-QQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDA 488
           Q Q  Q Q  QP  +     Q P  PP QQ P     QQ+ T       Q  P S PP +
Sbjct: 505 QSQPPQLQSSQPPYS-----QQPSQPPHQQSPAPYPSQQSTT-------QQHPQSQPPYS 552

Query: 489 APKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQ--PGTAQAQALGLA 546
            P+   P Q + P  P  P  L  ++ +A  QP      Q   ++Q  P   +       
Sbjct: 553 QPQAQSPYQQQQPQQP-APSTL--SQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609

Query: 547 QLAAAVPTSRGMPGTVQSGQAHLASSPPS-SQAPGALQECPPTLAPGMTLAPVQGTAHVV 605
             A++ P+     G  +     L S P S     G++ + P  +     L+P   T+ + 
Sbjct: 610 SQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP--MGTEGALSPGVSTSGIS 667

Query: 606 KGGATTSSPVVAQVPAAFYMQSVHLPG--KPQTLAVKRKADSEEER----DDVSTLGSML 659
                 S+P  AQ P + +  S HLPG   P    V   A   + R       +  G+ +
Sbjct: 668 SSQGEQSNP--AQSPFSPH-TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQM 724

Query: 660 PAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPP--PTLAMVSR 717
           P +  P  +S  +M    +    A+    +  N    +  +  P  ++ P  P+   +  
Sbjct: 725 PPR-PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHT 783

Query: 718 QMG 720
            MG
Sbjct: 784 GMG 786



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 51/184 (27%), Positives = 69/184 (37%), Gaps = 16/184 (8%)

Query: 426  QQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLP 485
            QQQQQQQQ+      Q +T   P      P+QQ    Q QQQ     +            
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPF-PSQQTTMYQQQQQNYKRPMDGTYGPPAKRHE 1385

Query: 486  PDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPV-QVVGTRQPGTAQAQALG 544
             +    P    Q +P    + P Q   A    A QP P   V    G   P TA A    
Sbjct: 1386 GEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATA---A 1442

Query: 545  LAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHV 604
              +  A  P ++      Q G+  + S+PP + A    Q  PP +  G    P+Q +A V
Sbjct: 1443 TERRPAGGPQNQ---FPFQFGRDRV-SAPPGTNAQ---QNMPPQMMGG----PIQASAEV 1491

Query: 605  VKGG 608
             + G
Sbjct: 1492 AQQG 1495



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 109/518 (21%), Positives = 169/518 (32%), Gaps = 87/518 (16%)

Query: 129  TQSVLLGNTTSPPLNQSQAQMYLR----PQLGNLLQVNRT-----------LGRNVPLAS 173
            T+   +G T  P + +    +Y       ++G L QVN+            +G +   AS
Sbjct: 1031 TEEKAMGMTNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090

Query: 174  QLILMPNGAVAAVQQEVPSAQSP--GVHADADQVQNLAVRNQQASA-----QGPQMQGST 226
             L       + A + ++   + P   + A AD  ++       + A     QGPQ   ST
Sbjct: 1091 SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQST 1150

Query: 227  QKAIPPGAS---------------PVSSLSQASSQALAVA-QASSGATNQ---------- 260
              ++  G                 P+  +S+++S  +  A    S +T Q          
Sbjct: 1151 SSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPG 1210

Query: 261  ---SLNLSQAGGGSG---NSIP-GSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQ 313
               S+N S   G      N  P GSM    G       GQ P+ GMG       G     
Sbjct: 1211 YQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAG----- 1265

Query: 314  PLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQ 373
              P    V +             +     G G +         +T AP   L+ S   + 
Sbjct: 1266 --PGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEG------NMSTGAPQPNLMPSNPDSG 1317

Query: 374  IQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQ 433
            +   S    QQQ   QQ+           H        +Q   + +    +QQ    QQQ
Sbjct: 1318 MYSPSRYPPQQQQQQQQR-----------HDSYGNQFSTQGTPSGSPFP-SQQTTMYQQQ 1365

Query: 434  QQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPP 493
            QQ  ++P   T   P          VP S  Q Q Q   + P  Q  P S    A P P 
Sbjct: 1366 QQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPP-AQPQPASQQQAAQPSPQ 1424

Query: 494  IPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTR---QPGTAQAQALGLAQLAA 550
              + ++   A        A +   A  P    P Q    R    PGT   Q +    +  
Sbjct: 1425 QDVYNQYGNA-YPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGG 1483

Query: 551  AVPTSR--GMPGTVQSGQAHLASSPPSSQAPGALQECP 586
             +  S      GT+  G+  +  +  + Q+ G+  + P
Sbjct: 1484 PIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGP 1521



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 60/296 (20%), Positives = 101/296 (34%), Gaps = 40/296 (13%)

Query: 21  SSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAA 80
           S  P     + Y  Q     Q  Q QP  +Q   Q   QQQ            Q A    
Sbjct: 523 SQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ---------QPAPSTL 573

Query: 81  SRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSP 140
           S+QA+ P   + Q Q T             +Q    SQ+ S+PS T            S 
Sbjct: 574 SQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMT------------SS 621

Query: 141 PLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQ----QEVPSAQSP 196
              Q    + L+ +  +L  ++ ++  ++P+ ++  L P  + + +     ++   AQSP
Sbjct: 622 KGGQEDMNLSLQSRPSSLPDLSGSID-DLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680

Query: 197 GVHADADQVQNL------------AVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQAS 244
                +  +  +            +V   ++    P      Q    P +    S+   S
Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 245 SQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG 300
               ++AQ   G   ++  + Q       S      P GG Q H G+G    + MG
Sbjct: 741 MNQSSIAQ-DRGYMQRNPQMPQYSSPQPGSALSPRQPSGG-QIHTGMGSYQQNSMG 794


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 166/723 (22%), Positives = 249/723 (34%), Gaps = 77/723 (10%)

Query: 14  GSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAV 73
           G  SS G   P  +  +     A    Q   R P+A       +  QQ    Q   LAA+
Sbjct: 125 GGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAAL 184

Query: 74  QQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVL 133
           Q          + P  ++        Q +      SA    + + ++SSP   T      
Sbjct: 185 QSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAA 244

Query: 134 LGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVPSA 193
               + PP + S +            Q    +G   P A+        A   + Q + S 
Sbjct: 245 AAAGSKPPPSSSASASSSSSSFAQ--QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSP 302

Query: 194 QSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQA 253
            S               R  Q    G    G        G + ++S    ++ A A A A
Sbjct: 303 SS--------------ARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAA 348

Query: 254 SSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQ 313
           +SG   Q  + +    GS          GGGGQ    L + P       S P    G ++
Sbjct: 349 ASGGAQQRSHHAPMSPGSS---------GGGGQP---LARTPQP-----SSPMDQMGKMR 391

Query: 314 PLPAAQTVTVSQ--GSQTEAESAAAKKAEADGSGQ-QNVGMNLTRTATPAPSQTLISSAT 370
           P P   T   SQ  G  +  +       +  GS   Q   M +   A     Q+ +   +
Sbjct: 392 PQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRA-----QSAMGGLS 446

Query: 371 YTQ-IQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQ 429
           YTQ I P+   QQ    + QQ Q     Q + H QQQ      Q      H Q + QQQ 
Sbjct: 447 YTQQIPPYG--QQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQP 504

Query: 430 QQQQQQ-QQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDA 488
           Q Q  Q Q  QP  +     Q P  PP QQ P     QQ+ T       Q  P S PP +
Sbjct: 505 QSQPPQLQSSQPPYS-----QQPSQPPHQQSPAPYPSQQSTT-------QQHPQSQPPYS 552

Query: 489 APKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQ--PGTAQAQALGLA 546
            P+   P Q + P  P  P  L  ++ +A  QP      Q   ++Q  P   +       
Sbjct: 553 QPQAQSPYQQQQPQQP-APSTL--SQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG 609

Query: 547 QLAAAVPTSRGMPGTVQSGQAHLASSPPS-SQAPGALQECPPTLAPGMTLAPVQGTAHVV 605
             A++ P+     G  +     L S P S     G++ + P  +     L+P   T+ + 
Sbjct: 610 SQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLP--MGTEGALSPGVSTSGIS 667

Query: 606 KGGATTSSPVVAQVPAAFYMQSVHLPG--KPQTLAVKRKADSEEER----DDVSTLGSML 659
                 S+P  AQ P + +  S HLPG   P    V   A   + R       +  G+ +
Sbjct: 668 SSQGEQSNP--AQSPFSPH-TSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQM 724

Query: 660 PAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPP--PTLAMVSR 717
           P +  P  +S  +M    +    A+    +  N    +  +  P  ++ P  P+   +  
Sbjct: 725 PPR-PPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHT 783

Query: 718 QMG 720
            MG
Sbjct: 784 GMG 786



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 30/96 (31%), Positives = 40/96 (41%), Gaps = 15/96 (15%)

Query: 426  QQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLP 485
            QQQQQQQQ+      Q +T   P      P+QQ    Q QQQ  +    P    +  S  
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPF-PSQQTTMYQQQQQVSSPAPLPRPMENRTS-- 1383

Query: 486  PDAAP-----------KPPIPIQSKPPVAPIKPPQL 510
            P  +P            PP+P     P AP++PP +
Sbjct: 1384 PSKSPFLHSGMKMQKAGPPVPASHIAP-APVQPPMI 1418



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 60/296 (20%), Positives = 101/296 (34%), Gaps = 40/296 (13%)

Query: 21  SSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAA 80
           S  P     + Y  Q     Q  Q QP  +Q   Q   QQQ            Q A    
Sbjct: 523 SQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQ---------QPAPSTL 573

Query: 81  SRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSP 140
           S+QA+ P   + Q Q T             +Q    SQ+ S+PS T            S 
Sbjct: 574 SQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMT------------SS 621

Query: 141 PLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQ----QEVPSAQSP 196
              Q    + L+ +  +L  ++ ++  ++P+ ++  L P  + + +     ++   AQSP
Sbjct: 622 KGGQEDMNLSLQSRPSSLPDLSGSID-DLPMGTEGALSPGVSTSGISSSQGEQSNPAQSP 680

Query: 197 GVHADADQVQNL------------AVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQAS 244
                +  +  +            +V   ++    P      Q    P +    S+   S
Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 245 SQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG 300
               ++AQ   G   ++  + Q       S      P GG Q H G+G    + MG
Sbjct: 741 MNQSSIAQ-DRGYMQRNPQMPQYSSPQPGSALSPRQPSGG-QIHTGMGSYQQNSMG 794


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 84/291 (28%), Positives = 118/291 (40%), Gaps = 38/291 (13%)

Query: 211  RNQQASAQGPQMQGSTQKAIPP-GASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGG 269
            + Q A  QG +++   Q++    G S V  ++ +SS  L  +Q  +   +  + L Q  G
Sbjct: 1900 QQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSH-VGLQQHTG 1958

Query: 270  GSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQP---LPAAQTVTVSQG 326
             +G  +P S         H                P     +V P   L    +  V Q 
Sbjct: 1959 PAGTMVPPSYSSQPYQSTH----------------PSTNPTLVDPTRHLQQRPSGYVHQQ 2002

Query: 327  SQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQI 386
            + T      + +  +  + QQ     +  T TP  +Q + +    T I P    QQQQQ 
Sbjct: 2003 APTYGHGLTSTQRFSHQTLQQTP---MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQ 2059

Query: 387  HLQQKQVVIQQQIAIHHQQQF---QHRQSQLLHTATHLQLAQQQQQQQQQQQ-------- 435
              QQ+Q   QQQ     QQQ+   Q +Q Q+L      Q  QQQQQQQQQQQ        
Sbjct: 2060 QQQQQQQQQQQQ---QQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQH 2116

Query: 436  QQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPP 486
            QQQQ Q      PQP   P  Q+    Q+QQQ QT  +   LQ    +  P
Sbjct: 2117 QQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQP 2167



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 49/139 (35%), Positives = 57/139 (41%), Gaps = 22/139 (15%)

Query: 370  TYTQIQPHSLIQQQQQIHL------QQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQL 423
            T TQ   H  +QQ   I        Q  Q  ++    +  QQQ Q +Q            
Sbjct: 2011 TSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQ------------ 2058

Query: 424  AQQQQQQQQQQQQQQQPQATTLTAPQPPQV--PPTQQVPPSQSQQQAQTLVVQPMLQSSP 481
             QQQQQQQQQQQQQQQ Q   +   Q  Q+     QQ    Q QQQ Q    Q   Q   
Sbjct: 2059 -QQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQ 2117

Query: 482  LSLPPDAAPKPPIPIQSKP 500
                  AAP  P P QS+P
Sbjct: 2118 QQQQQQAAPPQPQP-QSQP 2135



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 27/117 (23%), Positives = 38/117 (32%)

Query: 2    ETESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQ 61
            E + +Q               + Q  Q  + ++Q  Q L+  Q+Q    Q   Q   QQQ
Sbjct: 2050 EQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109

Query: 62   LSNAQLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQ 118
                Q H     QQA     +  S P       Q T  Q           Q +S +Q
Sbjct: 2110 QQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQLSNTQ 2166


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 132/571 (23%), Positives = 208/571 (36%), Gaps = 100/571 (17%)

Query: 8   NSNSTNGSSSSGGSSRPQIA-------------QMSLYERQAVQALQALQRQPN-----A 49
           NS++  GS    G  +P  +             Q SL  +Q V    A  ++PN     +
Sbjct: 140 NSSNNGGSGGINGEQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNS 199

Query: 50  AQYFHQFMLQQQLSNAQ-----LHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASI- 103
                +  + + LS  Q      +  + +   T+  S QA    T+T    T +    + 
Sbjct: 200 FLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMS-QAPLRKTNTLPSHTHSPGNGLF 258

Query: 104 NLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNR 163
           N+      +    + S S      +TQ  +  N           +  + P+L  L   N 
Sbjct: 259 NMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNR----YGDDPGEQLMDPELQELF--NE 312

Query: 164 TLGRNVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQ------VQNLAVRNQQASA 217
               +VP  S L L  N   A ++Q+ P     G  +          ++ + ++++ +  
Sbjct: 313 LTNISVPPMSDLEL-ENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPG 371

Query: 218 --QGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSI 275
             QGP   GS Q   PP A P  S++ ++        +   +  QS    Q G G+  ++
Sbjct: 372 LTQGPS--GSPQLR-PPSAGPAFSMANSALST----SSPIPSVPQSQAQPQTGSGASRAL 424

Query: 276 PGSMGPG---------GGGQAHGGLGQLPS-------SGMGGGSCPRKGTGVVQPLPAAQ 319
           P                  Q H  + Q          S +   + P  G    + +P+  
Sbjct: 425 PSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSP- 483

Query: 320 TVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQ---- 375
               S G QT +  ++     A GSGQ  V  N    A P+     +      + Q    
Sbjct: 484 ----SFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSR 539

Query: 376 -----PHSLIQQQQ------------QIHLQQKQVVIQQQ--IAIHHQQQFQHRQSQLLH 416
                PH  ++ +Q            Q + Q   V+  Q     +H+ QQ Q +Q Q   
Sbjct: 540 SFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQ 599

Query: 417 TATHLQLAQQQQQQQQQQQ--------QQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQA 468
                Q  QQQQQQQQQQQ        QQQQ Q ++++A Q  Q    QQ    Q QQQ 
Sbjct: 600 QQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQ 659

Query: 469 QTLVVQPMLQSSPLSLPPDAAPKPPIPIQSK 499
           Q    QP  Q +  SLP     + P+P+Q K
Sbjct: 660 QQQQQQPSSQPAQ-SLPSQPLLRSPLPLQQK 689



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 96/400 (24%), Positives = 144/400 (36%), Gaps = 86/400 (21%)

Query: 121 SSPSATTLTQSVLLGNTTSPPLNQSQA-QMYLRPQLGN--LLQVNRTLGRNVPLAS--QL 175
           S+P  +   + +++ +  SP L Q  +    LRP          N  L  + P+ S  Q 
Sbjct: 351 STPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQS 410

Query: 176 ILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGP---QMQGSTQKAIPP 232
              P     A  + +PS Q     + A Q++ +A   QQ +       Q Q +   A+P 
Sbjct: 411 QAQPQTGSGA-SRALPSWQEV---SHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPS 466

Query: 233 GASPVSS-LSQASSQALAVAQASSGATNQSLNLSQAGGGSGNS-IPGSMGPGGGGQAHGG 290
            A P      Q    + +  Q +     QS  +    GGSG S +  +     G  A GG
Sbjct: 467 SAGPSPGPFGQEKIPSPSFGQQTFSP--QSSPMPGVAGGSGQSKVMANYMYKAGPSAQGG 524

Query: 291 -----LGQLPS-------SGMGGGSCPRKGTGVVQPL---------PAAQTVTVSQGSQ- 328
                + Q P        +       PR+G    +PL             +V  SQ    
Sbjct: 525 HLDVLMQQKPQDLSRSFINNPHPAMEPRQGN--TKPLFHFNSDQANQQMPSVLPSQNKPS 582

Query: 329 ----TEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQIQPH-SLIQQQ 383
               T+ +    ++ +     QQ       +       Q+ IS+    Q Q   S  QQQ
Sbjct: 583 LLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQ 642

Query: 384 QQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQAT 443
           QQ   QQ+Q                                 QQQQQQQQQQQQQQP + 
Sbjct: 643 QQQQQQQQQ---------------------------------QQQQQQQQQQQQQQPSS- 668

Query: 444 TLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLS 483
                QP Q  P+Q +  S    Q + L+ Q  +Q+ P++
Sbjct: 669 -----QPAQSLPSQPLLRSPLPLQQKLLLQQ--MQNQPIA 701



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 96/450 (21%), Positives = 145/450 (32%), Gaps = 88/450 (19%)

Query: 190 VPSAQSPGV--HADADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQA 247
           +PS   P +  +    Q Q    + QQ   Q  Q Q   Q+      S +S+  Q   Q+
Sbjct: 575 LPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQS 634

Query: 248 LAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRK 307
              AQ       Q     Q                   Q      Q PSS     S P +
Sbjct: 635 SISAQQQQQQQQQQQQQQQQQQ----------------QQQQQQQQQPSS-QPAQSLPSQ 677

Query: 308 GTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNV-GMNLTRTATPAPSQTLI 366
              +  PLP  Q + + Q           + ++     Q +V G N   + +P P     
Sbjct: 678 PL-LRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPN 736

Query: 367 SSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQ 426
           + + Y   Q  SL+ QQ    L  K+  +Q+QI                           
Sbjct: 737 TGSGYMNSQ-QSLLNQQ----LMGKKQTLQRQI--------------------------- 764

Query: 427 QQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQ----SSPL 482
            +Q+QQ   QQQ        APQ        + PP    Q+     +QP  Q    SS +
Sbjct: 765 MEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTI 824

Query: 483 SLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVG------TRQPG 536
           SL  + A   P+   +      + P     +     + P     VQ +G        QP 
Sbjct: 825 SLNSNQALANPVSTHT-----ILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPN 879

Query: 537 TAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAP--------------GAL 582
           T    + G+ QL     T +  P  + + Q +     P +  P              G  
Sbjct: 880 TYSVTS-GMNQL-----TQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNS 933

Query: 583 QECPPTLAPGMTLAPVQGTAHVVKGGATTS 612
           Q+  P L   M   P Q T++V+    TT+
Sbjct: 934 QQLRPNLTHSMASMPPQRTSNVMITSNTTA 963


>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
            sapiens]
          Length = 1455

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 168/751 (22%), Positives = 277/751 (36%), Gaps = 104/751 (13%)

Query: 3    TESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQAL--QALQRQPNAAQYFHQFMLQQ 60
            T  +  + S  GS++SG S    + Q  L  +Q + ++   A     N  +     + QQ
Sbjct: 698  TIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQ 757

Query: 61   --QLSNAQLHSLAAVQQATI-----------AASRQASSPNTSTTQQQTTTTQASINLAT 107
              Q+ +     + +  + T+           A S    S NT + QQQ    Q  +    
Sbjct: 758  VSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQV--ME 815

Query: 108  TSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGR 167
            +SAA ++   QS+   +A    QS L  +T S   N  Q+ +Y   Q  +++    T   
Sbjct: 816  SSAAMVMEMQQSICQAAAQ--IQSELFPSTASANGNLQQSPVY--QQTSHMMSALST-NE 870

Query: 168  NVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGS-- 225
            ++ +  +L   P  AV+  +    + Q            + +   ++   Q  Q+Q S  
Sbjct: 871  DMQMQCELFSSP-PAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVF 929

Query: 226  -TQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGG-----GSGNSIPGS- 278
             T   +         ++  SS    ++  +SG   Q   L Q G       SGN +  S 
Sbjct: 930  QTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSS 989

Query: 279  ---------MGPGGGGQ-----AHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQ-TVTV 323
                       P    Q       G L   P+  +   +       +  P+  +Q T+ V
Sbjct: 990  HSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAV 1049

Query: 324  SQGSQTEAESAAAK---KAEADGSGQQNVGMNLTRTATP---APSQTLISSATYTQIQPH 377
             QGS    +  +           + Q N        A P   +P Q+  +S      Q  
Sbjct: 1050 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1109

Query: 378  SLIQQQQQIHLQQKQV------VIQQQIAI---------HHQQ--QFQHRQSQLLHTATH 420
            + I   Q   L Q+Q       + Q Q+A+           QQ   FQ + S +   +  
Sbjct: 1110 APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNS 1169

Query: 421  LQLAQQQQQQQQQQQQQQQPQA-------TTLTAPQPPQVPPTQQVPPSQSQQQAQTLVV 473
                QQQQQQQQQQQQQQQ Q+       T  T   P Q PP     P+Q+    Q    
Sbjct: 1170 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1229

Query: 474  QPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTR 533
            Q +      ++ P    + P+  QS+  V+ ++ P  G  +  ++Q P  H   Q+   +
Sbjct: 1230 QSIFHQQS-NMAPMNQEQQPMQFQSQSTVSSLQNP--GPTQSESSQTPLFHSSPQIQLVQ 1286

Query: 534  QPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGM 593
               ++Q Q + L    A++   +         Q+ L S  P +  PG +Q    +  P  
Sbjct: 1287 GSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYS--PQNNMPG-IQGATSSPQPQA 1343

Query: 594  TLAPVQGTAHVVKGGATT---SSPVVAQVPAAFYMQSVH------LPGKPQTLAVKRKAD 644
            TL       H   GG      +SP  +Q  +  ++  +       L   P TL  +  A 
Sbjct: 1344 TL------FHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAI 1397

Query: 645  SE------EERDDVSTLGSMLPAKASPVAES 669
            S+      E +  V+TL S    + SP+A S
Sbjct: 1398 SQPGQPQNEGQPPVTTLLSQQMPENSPLASS 1428



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 87/371 (23%), Positives = 131/371 (35%), Gaps = 48/371 (12%)

Query: 235 SPVSSLSQASSQALAVAQASSGATNQSL-NLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQ 293
           +P+   ++  S  +     S G+T Q+L N+S   G    S P S               
Sbjct: 532 TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSS-------------SH 578

Query: 294 LPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNL 353
           LPS          K     + L   QT  +SQ     A SA+++   +D   QQ      
Sbjct: 579 LPSENEKQQQIQPKAYNP-ETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQT 637

Query: 354 TRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQ 413
             T +    Q+  +    +Q+   S  QQQQQ  LQ++   +QQQI+ +      +  SQ
Sbjct: 638 RETQSREILQSDGTVVNLSQLTEAS--QQQQQSPLQEQAQTLQQQISSNIFPS-PNSVSQ 694

Query: 414 LLHTATHLQLAQ-----------QQQQQQQQQQQQQQPQATTLTAPQPPQ-VPPTQQVPP 461
           L +T   LQ                   QQ  + QQQ  +   +AP   + V        
Sbjct: 695 LQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADI 754

Query: 462 SQSQQQAQTLV-------VQPMLQSSPLSLPPDAA------PKPPIPIQSKPPVAPIKPP 508
            Q   Q Q+ V        +P + + P +L P  A       +  +  Q +      +  
Sbjct: 755 FQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVM 814

Query: 509 QLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSG--- 565
           +  AA +   QQ       Q+     P TA A    L Q      TS  M     +    
Sbjct: 815 ESSAAMVMEMQQSICQAAAQIQSELFPSTASANG-NLQQSPVYQQTSHMMSALSTNEDMQ 873

Query: 566 -QAHLASSPPS 575
            Q  L SSPP+
Sbjct: 874 MQCELFSSPPA 884



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 76/316 (24%), Positives = 127/316 (40%), Gaps = 70/316 (22%)

Query: 24   PQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQ---ATIAA 80
            PQ  Q ++++ Q   ++ A+Q    + +   Q   QQQ    Q  S+    Q   AT+A+
Sbjct: 1148 PQSQQGTMFQSQ--HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMAS 1205

Query: 81   SRQA---------SSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSS--------P 123
             +Q           +P  +  QQ  +      N+A  +  Q   + QS S+        P
Sbjct: 1206 PKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGP 1265

Query: 124  SATTLTQSVLLGNTT-------SPPLNQSQAQMYLRPQLGNLLQ--VNRTLGRNVPLASQ 174
            + +  +Q+ L  ++        SP   + Q  ++L P   + LQ  +N+   +  PL S 
Sbjct: 1266 TQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSP 1325

Query: 175  LILMP--NGAVAAVQQEVPSAQSPGVHADA----DQVQNLAVRNQQAS------------ 216
               MP   GA ++     P  Q+   H  A    +Q+QN    +QQ S            
Sbjct: 1326 QNNMPGIQGATSS-----PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1380

Query: 217  ---AQGP-----QMQGSTQKAIP--PGASPVSS-LSQASSQALAVAQASSGATNQS---L 262
                 GP     Q+   +Q   P   G  PV++ LSQ   +   +  ASS  TNQ+   +
Sbjct: 1381 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPL--ASSINTNQNIEKI 1438

Query: 263  NLSQAGGGSGNSIPGS 278
            +L  +    GN++ GS
Sbjct: 1439 DLLVSLQNQGNNLTGS 1454


>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
            sapiens]
          Length = 1531

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 168/751 (22%), Positives = 277/751 (36%), Gaps = 104/751 (13%)

Query: 3    TESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQAL--QALQRQPNAAQYFHQFMLQQ 60
            T  +  + S  GS++SG S    + Q  L  +Q + ++   A     N  +     + QQ
Sbjct: 774  TIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQ 833

Query: 61   --QLSNAQLHSLAAVQQATI-----------AASRQASSPNTSTTQQQTTTTQASINLAT 107
              Q+ +     + +  + T+           A S    S NT + QQQ    Q  +    
Sbjct: 834  VSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQV--ME 891

Query: 108  TSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGR 167
            +SAA ++   QS+   +A    QS L  +T S   N  Q+ +Y   Q  +++    T   
Sbjct: 892  SSAAMVMEMQQSICQAAAQ--IQSELFPSTASANGNLQQSPVY--QQTSHMMSALST-NE 946

Query: 168  NVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGS-- 225
            ++ +  +L   P  AV+  +    + Q            + +   ++   Q  Q+Q S  
Sbjct: 947  DMQMQCELFSSP-PAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVF 1005

Query: 226  -TQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGG-----GSGNSIPGS- 278
             T   +         ++  SS    ++  +SG   Q   L Q G       SGN +  S 
Sbjct: 1006 QTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSS 1065

Query: 279  ---------MGPGGGGQ-----AHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQ-TVTV 323
                       P    Q       G L   P+  +   +       +  P+  +Q T+ V
Sbjct: 1066 HSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAV 1125

Query: 324  SQGSQTEAESAAAK---KAEADGSGQQNVGMNLTRTATP---APSQTLISSATYTQIQPH 377
             QGS    +  +           + Q N        A P   +P Q+  +S      Q  
Sbjct: 1126 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1185

Query: 378  SLIQQQQQIHLQQKQV------VIQQQIAI---------HHQQ--QFQHRQSQLLHTATH 420
            + I   Q   L Q+Q       + Q Q+A+           QQ   FQ + S +   +  
Sbjct: 1186 APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNS 1245

Query: 421  LQLAQQQQQQQQQQQQQQQPQA-------TTLTAPQPPQVPPTQQVPPSQSQQQAQTLVV 473
                QQQQQQQQQQQQQQQ Q+       T  T   P Q PP     P+Q+    Q    
Sbjct: 1246 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1305

Query: 474  QPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTR 533
            Q +      ++ P    + P+  QS+  V+ ++ P  G  +  ++Q P  H   Q+   +
Sbjct: 1306 QSIFHQQS-NMAPMNQEQQPMQFQSQSTVSSLQNP--GPTQSESSQTPLFHSSPQIQLVQ 1362

Query: 534  QPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGM 593
               ++Q Q + L    A++   +         Q+ L S  P +  PG +Q    +  P  
Sbjct: 1363 GSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYS--PQNNMPG-IQGATSSPQPQA 1419

Query: 594  TLAPVQGTAHVVKGGATT---SSPVVAQVPAAFYMQSVH------LPGKPQTLAVKRKAD 644
            TL       H   GG      +SP  +Q  +  ++  +       L   P TL  +  A 
Sbjct: 1420 TL------FHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAI 1473

Query: 645  SE------EERDDVSTLGSMLPAKASPVAES 669
            S+      E +  V+TL S    + SP+A S
Sbjct: 1474 SQPGQPQNEGQPPVTTLLSQQMPENSPLASS 1504



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 87/371 (23%), Positives = 131/371 (35%), Gaps = 48/371 (12%)

Query: 235 SPVSSLSQASSQALAVAQASSGATNQSL-NLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQ 293
           +P+   ++  S  +     S G+T Q+L N+S   G    S P S               
Sbjct: 608 TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSS-------------SH 654

Query: 294 LPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNL 353
           LPS          K     + L   QT  +SQ     A SA+++   +D   QQ      
Sbjct: 655 LPSENEKQQQIQPKAYNP-ETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQT 713

Query: 354 TRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQ 413
             T +    Q+  +    +Q+   S  QQQQQ  LQ++   +QQQI+ +      +  SQ
Sbjct: 714 RETQSREILQSDGTVVNLSQLTEAS--QQQQQSPLQEQAQTLQQQISSNIFPS-PNSVSQ 770

Query: 414 LLHTATHLQLAQ-----------QQQQQQQQQQQQQQPQATTLTAPQPPQ-VPPTQQVPP 461
           L +T   LQ                   QQ  + QQQ  +   +AP   + V        
Sbjct: 771 LQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADI 830

Query: 462 SQSQQQAQTLV-------VQPMLQSSPLSLPPDAA------PKPPIPIQSKPPVAPIKPP 508
            Q   Q Q+ V        +P + + P +L P  A       +  +  Q +      +  
Sbjct: 831 FQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVM 890

Query: 509 QLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSG--- 565
           +  AA +   QQ       Q+     P TA A    L Q      TS  M     +    
Sbjct: 891 ESSAAMVMEMQQSICQAAAQIQSELFPSTASANG-NLQQSPVYQQTSHMMSALSTNEDMQ 949

Query: 566 -QAHLASSPPS 575
            Q  L SSPP+
Sbjct: 950 MQCELFSSPPA 960



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 76/316 (24%), Positives = 127/316 (40%), Gaps = 70/316 (22%)

Query: 24   PQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQ---ATIAA 80
            PQ  Q ++++ Q   ++ A+Q    + +   Q   QQQ    Q  S+    Q   AT+A+
Sbjct: 1224 PQSQQGTMFQSQ--HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMAS 1281

Query: 81   SRQA---------SSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSS--------P 123
             +Q           +P  +  QQ  +      N+A  +  Q   + QS S+        P
Sbjct: 1282 PKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGP 1341

Query: 124  SATTLTQSVLLGNTT-------SPPLNQSQAQMYLRPQLGNLLQ--VNRTLGRNVPLASQ 174
            + +  +Q+ L  ++        SP   + Q  ++L P   + LQ  +N+   +  PL S 
Sbjct: 1342 TQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSP 1401

Query: 175  LILMP--NGAVAAVQQEVPSAQSPGVHADA----DQVQNLAVRNQQAS------------ 216
               MP   GA ++     P  Q+   H  A    +Q+QN    +QQ S            
Sbjct: 1402 QNNMPGIQGATSS-----PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1456

Query: 217  ---AQGP-----QMQGSTQKAIP--PGASPVSS-LSQASSQALAVAQASSGATNQS---L 262
                 GP     Q+   +Q   P   G  PV++ LSQ   +   +  ASS  TNQ+   +
Sbjct: 1457 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPL--ASSINTNQNIEKI 1514

Query: 263  NLSQAGGGSGNSIPGS 278
            +L  +    GN++ GS
Sbjct: 1515 DLLVSLQNQGNNLTGS 1530


>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
            sapiens]
          Length = 1548

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 168/751 (22%), Positives = 277/751 (36%), Gaps = 104/751 (13%)

Query: 3    TESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQAL--QALQRQPNAAQYFHQFMLQQ 60
            T  +  + S  GS++SG S    + Q  L  +Q + ++   A     N  +     + QQ
Sbjct: 791  TIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQ 850

Query: 61   --QLSNAQLHSLAAVQQATI-----------AASRQASSPNTSTTQQQTTTTQASINLAT 107
              Q+ +     + +  + T+           A S    S NT + QQQ    Q  +    
Sbjct: 851  VSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQV--ME 908

Query: 108  TSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGR 167
            +SAA ++   QS+   +A    QS L  +T S   N  Q+ +Y   Q  +++    T   
Sbjct: 909  SSAAMVMEMQQSICQAAAQ--IQSELFPSTASANGNLQQSPVY--QQTSHMMSALST-NE 963

Query: 168  NVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGS-- 225
            ++ +  +L   P  AV+  +    + Q            + +   ++   Q  Q+Q S  
Sbjct: 964  DMQMQCELFSSP-PAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVF 1022

Query: 226  -TQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGG-----GSGNSIPGS- 278
             T   +         ++  SS    ++  +SG   Q   L Q G       SGN +  S 
Sbjct: 1023 QTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSS 1082

Query: 279  ---------MGPGGGGQ-----AHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQ-TVTV 323
                       P    Q       G L   P+  +   +       +  P+  +Q T+ V
Sbjct: 1083 HSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAV 1142

Query: 324  SQGSQTEAESAAAK---KAEADGSGQQNVGMNLTRTATP---APSQTLISSATYTQIQPH 377
             QGS    +  +           + Q N        A P   +P Q+  +S      Q  
Sbjct: 1143 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1202

Query: 378  SLIQQQQQIHLQQKQV------VIQQQIAI---------HHQQ--QFQHRQSQLLHTATH 420
            + I   Q   L Q+Q       + Q Q+A+           QQ   FQ + S +   +  
Sbjct: 1203 APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNS 1262

Query: 421  LQLAQQQQQQQQQQQQQQQPQA-------TTLTAPQPPQVPPTQQVPPSQSQQQAQTLVV 473
                QQQQQQQQQQQQQQQ Q+       T  T   P Q PP     P+Q+    Q    
Sbjct: 1263 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1322

Query: 474  QPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTR 533
            Q +      ++ P    + P+  QS+  V+ ++ P  G  +  ++Q P  H   Q+   +
Sbjct: 1323 QSIFHQQS-NMAPMNQEQQPMQFQSQSTVSSLQNP--GPTQSESSQTPLFHSSPQIQLVQ 1379

Query: 534  QPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGM 593
               ++Q Q + L    A++   +         Q+ L S  P +  PG +Q    +  P  
Sbjct: 1380 GSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYS--PQNNMPG-IQGATSSPQPQA 1436

Query: 594  TLAPVQGTAHVVKGGATT---SSPVVAQVPAAFYMQSVH------LPGKPQTLAVKRKAD 644
            TL       H   GG      +SP  +Q  +  ++  +       L   P TL  +  A 
Sbjct: 1437 TL------FHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAI 1490

Query: 645  SE------EERDDVSTLGSMLPAKASPVAES 669
            S+      E +  V+TL S    + SP+A S
Sbjct: 1491 SQPGQPQNEGQPPVTTLLSQQMPENSPLASS 1521



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 87/371 (23%), Positives = 131/371 (35%), Gaps = 48/371 (12%)

Query: 235 SPVSSLSQASSQALAVAQASSGATNQSL-NLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQ 293
           +P+   ++  S  +     S G+T Q+L N+S   G    S P S               
Sbjct: 625 TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSS-------------SH 671

Query: 294 LPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNL 353
           LPS          K     + L   QT  +SQ     A SA+++   +D   QQ      
Sbjct: 672 LPSENEKQQQIQPKAYNP-ETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQT 730

Query: 354 TRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQ 413
             T +    Q+  +    +Q+   S  QQQQQ  LQ++   +QQQI+ +      +  SQ
Sbjct: 731 RETQSREILQSDGTVVNLSQLTEAS--QQQQQSPLQEQAQTLQQQISSNIFPS-PNSVSQ 787

Query: 414 LLHTATHLQLAQ-----------QQQQQQQQQQQQQQPQATTLTAPQPPQ-VPPTQQVPP 461
           L +T   LQ                   QQ  + QQQ  +   +AP   + V        
Sbjct: 788 LQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADI 847

Query: 462 SQSQQQAQTLV-------VQPMLQSSPLSLPPDAA------PKPPIPIQSKPPVAPIKPP 508
            Q   Q Q+ V        +P + + P +L P  A       +  +  Q +      +  
Sbjct: 848 FQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVM 907

Query: 509 QLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSG--- 565
           +  AA +   QQ       Q+     P TA A    L Q      TS  M     +    
Sbjct: 908 ESSAAMVMEMQQSICQAAAQIQSELFPSTASANG-NLQQSPVYQQTSHMMSALSTNEDMQ 966

Query: 566 -QAHLASSPPS 575
            Q  L SSPP+
Sbjct: 967 MQCELFSSPPA 977



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 76/316 (24%), Positives = 127/316 (40%), Gaps = 70/316 (22%)

Query: 24   PQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQ---ATIAA 80
            PQ  Q ++++ Q   ++ A+Q    + +   Q   QQQ    Q  S+    Q   AT+A+
Sbjct: 1241 PQSQQGTMFQSQ--HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMAS 1298

Query: 81   SRQA---------SSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSS--------P 123
             +Q           +P  +  QQ  +      N+A  +  Q   + QS S+        P
Sbjct: 1299 PKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGP 1358

Query: 124  SATTLTQSVLLGNTT-------SPPLNQSQAQMYLRPQLGNLLQ--VNRTLGRNVPLASQ 174
            + +  +Q+ L  ++        SP   + Q  ++L P   + LQ  +N+   +  PL S 
Sbjct: 1359 TQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSP 1418

Query: 175  LILMP--NGAVAAVQQEVPSAQSPGVHADA----DQVQNLAVRNQQAS------------ 216
               MP   GA ++     P  Q+   H  A    +Q+QN    +QQ S            
Sbjct: 1419 QNNMPGIQGATSS-----PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1473

Query: 217  ---AQGP-----QMQGSTQKAIP--PGASPVSS-LSQASSQALAVAQASSGATNQS---L 262
                 GP     Q+   +Q   P   G  PV++ LSQ   +   +  ASS  TNQ+   +
Sbjct: 1474 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPL--ASSINTNQNIEKI 1531

Query: 263  NLSQAGGGSGNSIPGS 278
            +L  +    GN++ GS
Sbjct: 1532 DLLVSLQNQGNNLTGS 1547


>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
            sapiens]
          Length = 1549

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 168/751 (22%), Positives = 277/751 (36%), Gaps = 104/751 (13%)

Query: 3    TESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQAL--QALQRQPNAAQYFHQFMLQQ 60
            T  +  + S  GS++SG S    + Q  L  +Q + ++   A     N  +     + QQ
Sbjct: 792  TIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQ 851

Query: 61   --QLSNAQLHSLAAVQQATI-----------AASRQASSPNTSTTQQQTTTTQASINLAT 107
              Q+ +     + +  + T+           A S    S NT + QQQ    Q  +    
Sbjct: 852  VSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQV--ME 909

Query: 108  TSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGR 167
            +SAA ++   QS+   +A    QS L  +T S   N  Q+ +Y   Q  +++    T   
Sbjct: 910  SSAAMVMEMQQSICQAAAQ--IQSELFPSTASANGNLQQSPVY--QQTSHMMSALST-NE 964

Query: 168  NVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGS-- 225
            ++ +  +L   P  AV+  +    + Q            + +   ++   Q  Q+Q S  
Sbjct: 965  DMQMQCELFSSP-PAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVF 1023

Query: 226  -TQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGG-----GSGNSIPGS- 278
             T   +         ++  SS    ++  +SG   Q   L Q G       SGN +  S 
Sbjct: 1024 QTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSS 1083

Query: 279  ---------MGPGGGGQ-----AHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQ-TVTV 323
                       P    Q       G L   P+  +   +       +  P+  +Q T+ V
Sbjct: 1084 HSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAV 1143

Query: 324  SQGSQTEAESAAAK---KAEADGSGQQNVGMNLTRTATP---APSQTLISSATYTQIQPH 377
             QGS    +  +           + Q N        A P   +P Q+  +S      Q  
Sbjct: 1144 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1203

Query: 378  SLIQQQQQIHLQQKQV------VIQQQIAI---------HHQQ--QFQHRQSQLLHTATH 420
            + I   Q   L Q+Q       + Q Q+A+           QQ   FQ + S +   +  
Sbjct: 1204 APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNS 1263

Query: 421  LQLAQQQQQQQQQQQQQQQPQA-------TTLTAPQPPQVPPTQQVPPSQSQQQAQTLVV 473
                QQQQQQQQQQQQQQQ Q+       T  T   P Q PP     P+Q+    Q    
Sbjct: 1264 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1323

Query: 474  QPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTR 533
            Q +      ++ P    + P+  QS+  V+ ++ P  G  +  ++Q P  H   Q+   +
Sbjct: 1324 QSIFHQQS-NMAPMNQEQQPMQFQSQSTVSSLQNP--GPTQSESSQTPLFHSSPQIQLVQ 1380

Query: 534  QPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGM 593
               ++Q Q + L    A++   +         Q+ L S  P +  PG +Q    +  P  
Sbjct: 1381 GSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYS--PQNNMPG-IQGATSSPQPQA 1437

Query: 594  TLAPVQGTAHVVKGGATT---SSPVVAQVPAAFYMQSVH------LPGKPQTLAVKRKAD 644
            TL       H   GG      +SP  +Q  +  ++  +       L   P TL  +  A 
Sbjct: 1438 TL------FHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAI 1491

Query: 645  SE------EERDDVSTLGSMLPAKASPVAES 669
            S+      E +  V+TL S    + SP+A S
Sbjct: 1492 SQPGQPQNEGQPPVTTLLSQQMPENSPLASS 1522



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 87/371 (23%), Positives = 131/371 (35%), Gaps = 48/371 (12%)

Query: 235 SPVSSLSQASSQALAVAQASSGATNQSL-NLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQ 293
           +P+   ++  S  +     S G+T Q+L N+S   G    S P S               
Sbjct: 626 TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSS-------------SH 672

Query: 294 LPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNL 353
           LPS          K     + L   QT  +SQ     A SA+++   +D   QQ      
Sbjct: 673 LPSENEKQQQIQPKAYNP-ETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQT 731

Query: 354 TRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQ 413
             T +    Q+  +    +Q+   S  QQQQQ  LQ++   +QQQI+ +      +  SQ
Sbjct: 732 RETQSREILQSDGTVVNLSQLTEAS--QQQQQSPLQEQAQTLQQQISSNIFPS-PNSVSQ 788

Query: 414 LLHTATHLQLAQ-----------QQQQQQQQQQQQQQPQATTLTAPQPPQ-VPPTQQVPP 461
           L +T   LQ                   QQ  + QQQ  +   +AP   + V        
Sbjct: 789 LQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADI 848

Query: 462 SQSQQQAQTLV-------VQPMLQSSPLSLPPDAA------PKPPIPIQSKPPVAPIKPP 508
            Q   Q Q+ V        +P + + P +L P  A       +  +  Q +      +  
Sbjct: 849 FQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVM 908

Query: 509 QLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSG--- 565
           +  AA +   QQ       Q+     P TA A    L Q      TS  M     +    
Sbjct: 909 ESSAAMVMEMQQSICQAAAQIQSELFPSTASANG-NLQQSPVYQQTSHMMSALSTNEDMQ 967

Query: 566 -QAHLASSPPS 575
            Q  L SSPP+
Sbjct: 968 MQCELFSSPPA 978



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 76/316 (24%), Positives = 127/316 (40%), Gaps = 70/316 (22%)

Query: 24   PQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQ---ATIAA 80
            PQ  Q ++++ Q   ++ A+Q    + +   Q   QQQ    Q  S+    Q   AT+A+
Sbjct: 1242 PQSQQGTMFQSQ--HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMAS 1299

Query: 81   SRQA---------SSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSS--------P 123
             +Q           +P  +  QQ  +      N+A  +  Q   + QS S+        P
Sbjct: 1300 PKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGP 1359

Query: 124  SATTLTQSVLLGNTT-------SPPLNQSQAQMYLRPQLGNLLQ--VNRTLGRNVPLASQ 174
            + +  +Q+ L  ++        SP   + Q  ++L P   + LQ  +N+   +  PL S 
Sbjct: 1360 TQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSP 1419

Query: 175  LILMP--NGAVAAVQQEVPSAQSPGVHADA----DQVQNLAVRNQQAS------------ 216
               MP   GA ++     P  Q+   H  A    +Q+QN    +QQ S            
Sbjct: 1420 QNNMPGIQGATSS-----PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1474

Query: 217  ---AQGP-----QMQGSTQKAIP--PGASPVSS-LSQASSQALAVAQASSGATNQS---L 262
                 GP     Q+   +Q   P   G  PV++ LSQ   +   +  ASS  TNQ+   +
Sbjct: 1475 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPL--ASSINTNQNIEKI 1532

Query: 263  NLSQAGGGSGNSIPGS 278
            +L  +    GN++ GS
Sbjct: 1533 DLLVSLQNQGNNLTGS 1548


>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
            sapiens]
          Length = 1455

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 168/751 (22%), Positives = 277/751 (36%), Gaps = 104/751 (13%)

Query: 3    TESEQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQAL--QALQRQPNAAQYFHQFMLQQ 60
            T  +  + S  GS++SG S    + Q  L  +Q + ++   A     N  +     + QQ
Sbjct: 698  TIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADIFQQ 757

Query: 61   --QLSNAQLHSLAAVQQATI-----------AASRQASSPNTSTTQQQTTTTQASINLAT 107
              Q+ +     + +  + T+           A S    S NT + QQQ    Q  +    
Sbjct: 758  VSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQV--ME 815

Query: 108  TSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGR 167
            +SAA ++   QS+   +A    QS L  +T S   N  Q+ +Y   Q  +++    T   
Sbjct: 816  SSAAMVMEMQQSICQAAAQ--IQSELFPSTASANGNLQQSPVY--QQTSHMMSALST-NE 870

Query: 168  NVPLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGS-- 225
            ++ +  +L   P  AV+  +    + Q            + +   ++   Q  Q+Q S  
Sbjct: 871  DMQMQCELFSSP-PAVSGNETSTTTTQQVATPGTTMFQTSSSGDGEETGTQAKQIQNSVF 929

Query: 226  -TQKAIPPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGG-----GSGNSIPGS- 278
             T   +         ++  SS    ++  +SG   Q   L Q G       SGN +  S 
Sbjct: 930  QTMVQMQHSGDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQSS 989

Query: 279  ---------MGPGGGGQ-----AHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQ-TVTV 323
                       P    Q       G L   P+  +   +       +  P+  +Q T+ V
Sbjct: 990  HSQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPPMFHSQSTIAV 1049

Query: 324  SQGSQTEAESAAAK---KAEADGSGQQNVGMNLTRTATP---APSQTLISSATYTQIQPH 377
             QGS    +  +           + Q N        A P   +P Q+  +S      Q  
Sbjct: 1050 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1109

Query: 378  SLIQQQQQIHLQQKQV------VIQQQIAI---------HHQQ--QFQHRQSQLLHTATH 420
            + I   Q   L Q+Q       + Q Q+A+           QQ   FQ + S +   +  
Sbjct: 1110 APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSIVAMQSNS 1169

Query: 421  LQLAQQQQQQQQQQQQQQQPQA-------TTLTAPQPPQVPPTQQVPPSQSQQQAQTLVV 473
                QQQQQQQQQQQQQQQ Q+       T  T   P Q PP     P+Q+    Q    
Sbjct: 1170 PSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQN 1229

Query: 474  QPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTR 533
            Q +      ++ P    + P+  QS+  V+ ++ P  G  +  ++Q P  H   Q+   +
Sbjct: 1230 QSIFHQQS-NMAPMNQEQQPMQFQSQSTVSSLQNP--GPTQSESSQTPLFHSSPQIQLVQ 1286

Query: 534  QPGTAQAQALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGM 593
               ++Q Q + L    A++   +         Q+ L S  P +  PG +Q    +  P  
Sbjct: 1287 GSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYS--PQNNMPG-IQGATSSPQPQA 1343

Query: 594  TLAPVQGTAHVVKGGATT---SSPVVAQVPAAFYMQSVH------LPGKPQTLAVKRKAD 644
            TL       H   GG      +SP  +Q  +  ++  +       L   P TL  +  A 
Sbjct: 1344 TL------FHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCSQLLTSGPATLPDQLMAI 1397

Query: 645  SE------EERDDVSTLGSMLPAKASPVAES 669
            S+      E +  V+TL S    + SP+A S
Sbjct: 1398 SQPGQPQNEGQPPVTTLLSQQMPENSPLASS 1428



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 87/371 (23%), Positives = 131/371 (35%), Gaps = 48/371 (12%)

Query: 235 SPVSSLSQASSQALAVAQASSGATNQSL-NLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQ 293
           +P+   ++  S  +     S G+T Q+L N+S   G    S P S               
Sbjct: 532 TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIAGNGSFSSPSS-------------SH 578

Query: 294 LPSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNL 353
           LPS          K     + L   QT  +SQ     A SA+++   +D   QQ      
Sbjct: 579 LPSENEKQQQIQPKAYNP-ETLTTIQTQDISQPGTFPAVSASSQLPNSDALLQQATQFQT 637

Query: 354 TRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQ 413
             T +    Q+  +    +Q+   S  QQQQQ  LQ++   +QQQI+ +      +  SQ
Sbjct: 638 RETQSREILQSDGTVVNLSQLTEAS--QQQQQSPLQEQAQTLQQQISSNIFPS-PNSVSQ 694

Query: 414 LLHTATHLQLAQ-----------QQQQQQQQQQQQQQPQATTLTAPQPPQ-VPPTQQVPP 461
           L +T   LQ                   QQ  + QQQ  +   +AP   + V        
Sbjct: 695 LQNTIQQLQAGSFTGSTASGSSGSVDLVQQVLEAQQQLSSVLFSAPDGNENVQEQLSADI 754

Query: 462 SQSQQQAQTLV-------VQPMLQSSPLSLPPDAA------PKPPIPIQSKPPVAPIKPP 508
            Q   Q Q+ V        +P + + P +L P  A       +  +  Q +      +  
Sbjct: 755 FQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVM 814

Query: 509 QLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSG--- 565
           +  AA +   QQ       Q+     P TA A    L Q      TS  M     +    
Sbjct: 815 ESSAAMVMEMQQSICQAAAQIQSELFPSTASANG-NLQQSPVYQQTSHMMSALSTNEDMQ 873

Query: 566 -QAHLASSPPS 575
            Q  L SSPP+
Sbjct: 874 MQCELFSSPPA 884



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 76/316 (24%), Positives = 127/316 (40%), Gaps = 70/316 (22%)

Query: 24   PQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQ---ATIAA 80
            PQ  Q ++++ Q   ++ A+Q    + +   Q   QQQ    Q  S+    Q   AT+A+
Sbjct: 1148 PQSQQGTMFQSQ--HSIVAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMAS 1205

Query: 81   SRQA---------SSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSS--------P 123
             +Q           +P  +  QQ  +      N+A  +  Q   + QS S+        P
Sbjct: 1206 PKQPPPNMIFNPNQNPMANQEQQNQSIFHQQSNMAPMNQEQQPMQFQSQSTVSSLQNPGP 1265

Query: 124  SATTLTQSVLLGNTT-------SPPLNQSQAQMYLRPQLGNLLQ--VNRTLGRNVPLASQ 174
            + +  +Q+ L  ++        SP   + Q  ++L P   + LQ  +N+   +  PL S 
Sbjct: 1266 TQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQDMQQSPLYSP 1325

Query: 175  LILMP--NGAVAAVQQEVPSAQSPGVHADA----DQVQNLAVRNQQAS------------ 216
               MP   GA ++     P  Q+   H  A    +Q+QN    +QQ S            
Sbjct: 1326 QNNMPGIQGATSS-----PQPQATLFHNTAGGTMNQLQNSPGSSQQTSGMFLFGIQNNCS 1380

Query: 217  ---AQGP-----QMQGSTQKAIP--PGASPVSS-LSQASSQALAVAQASSGATNQS---L 262
                 GP     Q+   +Q   P   G  PV++ LSQ   +   +  ASS  TNQ+   +
Sbjct: 1381 QLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTLLSQQMPENSPL--ASSINTNQNIEKI 1438

Query: 263  NLSQAGGGSGNSIPGS 278
            +L  +    GN++ GS
Sbjct: 1439 DLLVSLQNQGNNLTGS 1454


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 61/181 (33%), Positives = 83/181 (45%), Gaps = 22/181 (12%)

Query: 348 NVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQV---VIQQQIAIH-- 402
           +V M   +  TP   Q ++     +  Q  +L+QQQQ + LQQ+Q+     +QQ  +H  
Sbjct: 90  SVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ 149

Query: 403 ----HQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQ 458
                QQQ Q +Q Q        Q  QQQQQQQQQQQQQQQ         Q  Q    QQ
Sbjct: 150 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 209

Query: 459 VPPSQSQQQAQTLVVQPMLQSSPL---------SLPPDAAPKPPIPIQSKPPVAPIKPPQ 509
           +   Q   Q Q L +Q + Q   L         S+PP  A    +P+QS P  A + P +
Sbjct: 210 LAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQA---ALPVQSLPQ-AGLSPAE 265

Query: 510 L 510
           +
Sbjct: 266 I 266



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 39/123 (31%), Positives = 49/123 (39%), Gaps = 6/123 (4%)

Query: 346 QQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQ 405
           Q+ + + L +       Q         Q Q     QQQQQ   QQ+Q   QQ      ++
Sbjct: 143 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQHPGKQAKE 199

Query: 406 QFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQ 465
           Q Q +Q Q    A  L     QQQ  Q QQ QQQ    +L       +PP Q   P QS 
Sbjct: 200 QQQQQQQQQQLAAQQLVF---QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSL 256

Query: 466 QQA 468
            QA
Sbjct: 257 PQA 259


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 61/181 (33%), Positives = 83/181 (45%), Gaps = 22/181 (12%)

Query: 348 NVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQV---VIQQQIAIH-- 402
           +V M   +  TP   Q ++     +  Q  +L+QQQQ + LQQ+Q+     +QQ  +H  
Sbjct: 115 SVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ 174

Query: 403 ----HQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQ 458
                QQQ Q +Q Q        Q  QQQQQQQQQQQQQQQ         Q  Q    QQ
Sbjct: 175 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 234

Query: 459 VPPSQSQQQAQTLVVQPMLQSSPL---------SLPPDAAPKPPIPIQSKPPVAPIKPPQ 509
           +   Q   Q Q L +Q + Q   L         S+PP  A    +P+QS P  A + P +
Sbjct: 235 LAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQA---ALPVQSLPQ-AGLSPAE 290

Query: 510 L 510
           +
Sbjct: 291 I 291



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 39/123 (31%), Positives = 49/123 (39%), Gaps = 6/123 (4%)

Query: 346 QQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQ 405
           Q+ + + L +       Q         Q Q     QQQQQ   QQ+Q   QQ      ++
Sbjct: 168 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQHPGKQAKE 224

Query: 406 QFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQ 465
           Q Q +Q Q    A  L     QQQ  Q QQ QQQ    +L       +PP Q   P QS 
Sbjct: 225 QQQQQQQQQQLAAQQLVF---QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSL 281

Query: 466 QQA 468
            QA
Sbjct: 282 PQA 284


>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
          Length = 623

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 60/178 (33%), Positives = 81/178 (45%), Gaps = 22/178 (12%)

Query: 351 MNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQV---VIQQQIAIH----- 402
           M   +  TP   Q ++     +  Q  +L+QQQQ + LQQ+Q+     +QQ  +H     
Sbjct: 1   MMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQ 60

Query: 403 -HQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPP 461
             QQQ Q +Q Q        Q  QQQQQQQQQQQQQQQ         Q  Q    QQ+  
Sbjct: 61  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120

Query: 462 SQSQQQAQTLVVQPMLQSSPL---------SLPPDAAPKPPIPIQSKPPVAPIKPPQL 510
            Q   Q Q L +Q + Q   L         S+PP  A    +P+QS P  A + P ++
Sbjct: 121 QQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQA---ALPVQSLPQ-AGLSPAEI 174



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 39/123 (31%), Positives = 49/123 (39%), Gaps = 6/123 (4%)

Query: 346 QQNVGMNLTRTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQ 405
           Q+ + + L +       Q         Q Q     QQQQQ   QQ+Q   QQ      ++
Sbjct: 51  QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---QQHPGKQAKE 107

Query: 406 QFQHRQSQLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQ 465
           Q Q +Q Q    A  L     QQQ  Q QQ QQQ    +L       +PP Q   P QS 
Sbjct: 108 QQQQQQQQQQLAAQQLVF---QQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSL 164

Query: 466 QQA 468
            QA
Sbjct: 165 PQA 167


>gi|53692193 Scm-like with four mbt domains 1 [Homo sapiens]
          Length = 866

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 52/151 (34%), Positives = 75/151 (49%), Gaps = 6/151 (3%)

Query: 857  GPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGER--DLG 914
            G   S S+ + ++ Q +     E S + S +SS  ++   TS  P   R     R     
Sbjct: 708  GDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFS 767

Query: 915  NPNTAPPTPE---LHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQA 971
            +    PP+P+   +     + L SNP +WSV +V  FI S   C  +A  F  QEIDGQA
Sbjct: 768  DDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTD-CAPLARIFLDQEIDGQA 826

Query: 972  LLLLKEEHLMSAMNIKLGPALKICAKINVLK 1002
            LLLL    +   M++KLGPA+K+C  I  +K
Sbjct: 827  LLLLTLPTVQECMDLKLGPAIKLCHHIERIK 857


>gi|53692191 Scm-like with four mbt domains 1 [Homo sapiens]
          Length = 866

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 52/151 (34%), Positives = 75/151 (49%), Gaps = 6/151 (3%)

Query: 857  GPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGER--DLG 914
            G   S S+ + ++ Q +     E S + S +SS  ++   TS  P   R     R     
Sbjct: 708  GDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFS 767

Query: 915  NPNTAPPTPE---LHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQA 971
            +    PP+P+   +     + L SNP +WSV +V  FI S   C  +A  F  QEIDGQA
Sbjct: 768  DDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTD-CAPLARIFLDQEIDGQA 826

Query: 972  LLLLKEEHLMSAMNIKLGPALKICAKINVLK 1002
            LLLL    +   M++KLGPA+K+C  I  +K
Sbjct: 827  LLLLTLPTVQECMDLKLGPAIKLCHHIERIK 857


>gi|53692195 Scm-like with four mbt domains 1 [Homo sapiens]
          Length = 866

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 52/151 (34%), Positives = 75/151 (49%), Gaps = 6/151 (3%)

Query: 857  GPRRSSSDIARAKIQGKCHRGQEDSSRGSDNSSYDEALSPTSPGPLSVRAGHGER--DLG 914
            G   S S+ + ++ Q +     E S + S +SS  ++   TS  P   R     R     
Sbjct: 708  GDDDSLSEGSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFS 767

Query: 915  NPNTAPPTPE---LHGINPVFLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQA 971
            +    PP+P+   +     + L SNP +WSV +V  FI S   C  +A  F  QEIDGQA
Sbjct: 768  DDENKPPSPKEIRIEVAERLHLDSNPLKWSVADVVRFIRSTD-CAPLARIFLDQEIDGQA 826

Query: 972  LLLLKEEHLMSAMNIKLGPALKICAKINVLK 1002
            LLLL    +   M++KLGPA+K+C  I  +K
Sbjct: 827  LLLLTLPTVQECMDLKLGPAIKLCHHIERIK 857


>gi|32699038 sterile alpha motif domain containing 7 [Homo sapiens]
          Length = 446

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 35/88 (39%), Positives = 52/88 (59%), Gaps = 4/88 (4%)

Query: 916 PNTAPPTPELHGINPV----FLSSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQA 971
           P   P  P  H +  +     L  +  +W+V++V+ FI SL GC + A+ F+   IDG+ 
Sbjct: 299 PVPRPSLPGTHALVTIGGNLSLDEDIQKWTVDDVHSFIRSLPGCSDYAQVFKDHAIDGET 358

Query: 972 LLLLKEEHLMSAMNIKLGPALKICAKIN 999
           L LL EEHL   M +KLGPALKI ++++
Sbjct: 359 LPLLTEEHLRGTMGLKLGPALKIQSQVS 386


>gi|55770872 l(3)mbt-like 3 isoform b [Homo sapiens]
          Length = 755

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 33/69 (47%), Positives = 48/69 (69%)

Query: 934  SSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALK 993
            +S  S+WS +EV EFI SL GC+E  + F+ ++IDG+A LL+ +  ++  M+IKLGPALK
Sbjct: 677  ASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALK 736

Query: 994  ICAKINVLK 1002
            I   I + K
Sbjct: 737  IFNSILMFK 745


>gi|55770870 l(3)mbt-like 3 isoform a [Homo sapiens]
          Length = 780

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 33/69 (47%), Positives = 48/69 (69%)

Query: 934  SSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALK 993
            +S  S+WS +EV EFI SL GC+E  + F+ ++IDG+A LL+ +  ++  M+IKLGPALK
Sbjct: 702  ASKVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALK 761

Query: 994  ICAKINVLK 1002
            I   I + K
Sbjct: 762  IFNSILMFK 770


>gi|158138528 l(3)mbt-like 4 [Homo sapiens]
          Length = 623

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 33/71 (46%), Positives = 50/71 (70%)

Query: 934  SSNPSRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALK 993
            +S  +RW+V+EV EF+ SL GC+E A+ F+ ++IDG+A LLL +  ++  M IKLGPALK
Sbjct: 537  ASQVARWTVDEVAEFVQSLLGCEEHAKCFKKEQIDGKAFLLLTQTDIVKVMKIKLGPALK 596

Query: 994  ICAKINVLKET 1004
            I   I + + +
Sbjct: 597  IYNSILMFRHS 607


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 93/359 (25%), Positives = 141/359 (39%), Gaps = 54/359 (15%)

Query: 248 LAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRK 307
           L+V     GA N +L  +++     N   G MG G   +   G     +SG G       
Sbjct: 125 LSVQIEGEGAINLALAQNRSQDVRMN---GPMGAGNSVRMEAGFPM--ASGPGIIRMNNP 179

Query: 308 GTGVVQPLPAAQTVTVSQGSQTEAESAAAKKA-EADGSGQQNVGMNLTRTATPAPSQTLI 366
            T ++ P     +  ++ G   E +    + A ++D       G+++ + + P+ S    
Sbjct: 180 ATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSL--- 236

Query: 367 SSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQ 426
            +  +  +QP S+ +Q    +  Q Q   QQQ     QQQ Q +Q Q           QQ
Sbjct: 237 -APPHHPMQPVSVNRQMNPANFPQLQQQQQQQ----QQQQQQQQQQQ-----------QQ 280

Query: 427 QQQQQ-----QQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSP 481
           QQQQQ      QQ QQQQPQ        P QVP    VPP  +Q  +  L   P   S  
Sbjct: 281 QQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVP----VPPGWNQLPSGALQPPPAQGSLG 336

Query: 482 LSLPPDAAPKPPIP------IQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQP 535
                    K P+P      +Q++P +A ++ P            PPP  P       Q 
Sbjct: 337 TMTANQGWKKAPLPGPMQQQLQARPSLATVQTP----------SHPPPPYPFGSQQASQA 386

Query: 536 GTAQAQALGLAQLAA-AVPTSRGMPGTVQS--GQAHLASSPPSSQAPGALQECPPTLAP 591
            T   Q     Q  A  + + +G P  V +   Q HL +  P+S +P + Q+  P  +P
Sbjct: 387 HTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPAS-SPSSFQQGSPASSP 444



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 179/832 (21%), Positives = 285/832 (34%), Gaps = 133/832 (15%)

Query: 20   GSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLA------AV 73
            G+ +P  AQ SL     + A Q  ++ P       Q   +  L+  Q  S          
Sbjct: 324  GALQPPPAQGSL---GTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGS 380

Query: 74   QQATIAASR--QASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQS 131
            QQA+ A +   Q S+P   T  Q  +       + T      ++     SSPS+      
Sbjct: 381  QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440

Query: 132  VLLGNTTSPPLNQSQAQMYLRPQLGNLLQVNRTLGRNVPLASQLILMPNGAVAAVQQEVP 191
                  +SP +NQ+Q QM  RP   N L                   P G     QQ V 
Sbjct: 441  A-----SSPTVNQTQQQMGPRPPQNNPL-------------------PQG----FQQPVS 472

Query: 192  SAQSPGVHADADQVQNLAVRNQQASAQGPQM----QGSTQKAIPPG-----ASPVSSLSQ 242
            S     +    +   N  V  QQ   QGPQ      G   K +PPG     A+P     Q
Sbjct: 473  SPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQ 532

Query: 243  ASSQALAVAQASSGATNQSLNLS-QAGGGSG-----NSIPGSMGPGGGGQAH--GGLGQL 294
              S   A    +SGA     N + Q  GG G     N +  S GP    Q    G  G +
Sbjct: 533  VPS-TTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNM 591

Query: 295  PSSGMGGGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLT 354
             +   G    P+     +Q  P     +   G   +   +  +  +  G+      M L+
Sbjct: 592  NNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILS 651

Query: 355  RTATPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQ--QIAIHHQQQFQHRQS 412
            R       Q +++        P   +    Q     KQ++ QQ  Q+   H Q    +  
Sbjct: 652  RAQLMPQGQMMVN-------PPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQ 704

Query: 413  QLLHTATHLQLAQQQQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLV 472
             LL     ++     Q Q  +QQ   Q Q+  +  P P Q+    + P    Q       
Sbjct: 705  VLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVM--PGPAQI---MRGPTPNMQGNMVQFT 759

Query: 473  VQPMLQSSPLSLPPDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGT 532
             Q   Q  P   P + +P   + IQ +     ++PP            P PH+  Q    
Sbjct: 760  GQMSGQMLPQQGPVNNSPSQVMGIQGQ----VLRPP-----------GPSPHMAQQ---H 801

Query: 533  RQPGTAQAQALGLAQLA--AAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLA 590
              P T     + L+Q+    ++  +  +P  VQ+ Q + AS    S   G     P + A
Sbjct: 802  GDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFS-GHGMSFNAPFSGA 860

Query: 591  P-GMTLAPVQGTAHVVKGGATTSSPVV-----AQVPAAFY----MQSVHLPGKPQTLAVK 640
            P G  ++  Q     V    T +SP++     + + A  +     Q+     KP+     
Sbjct: 861  PNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPP 920

Query: 641  RKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPS--SEL 698
            RK  + ++  D++T  +  PA      + P   ++  +L      +   +   P   S+ 
Sbjct: 921  RKKKNSQQ--DLNTPDTR-PAGLEEADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQP 977

Query: 699  VALTPAPSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVIQEGAEPFPVGCSQ-- 756
            V   P   +PP  +  V+      +PPQ   +PQ          + +  +P P    Q  
Sbjct: 978  VEQRPLQQMPPQLMQHVA---PPPQPPQQQPQPQ----------LPQQQQPPPPSQPQSQ 1024

Query: 757  -----------LLKESEKPLQTGLPTGLTENQSGGPLGVDSPSAELDKKANL 797
                       +L   + P    LP     +   GPL  DS    + +  ++
Sbjct: 1025 QQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSV 1076



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 172/822 (20%), Positives = 270/822 (32%), Gaps = 135/822 (16%)

Query: 6    EQNSNSTNGSSSSGGSSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNA 65
            + N N  +      G  + Q+            +L  +    N  Q     + Q  LSN 
Sbjct: 550  QANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNM 609

Query: 66   QLHSLAAVQQATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSA 125
            Q           +   +Q         QQQ T      N    S AQL+ + Q + +P +
Sbjct: 610  QGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQ--NPMILSRAQLMPQGQMMVNPPS 667

Query: 126  TTLTQSVLLGNTTSPPLNQSQAQMY------LRPQLGNLLQVNRTLGRNVP--------- 170
              L  S          L+Q   QM       + PQ   LLQ N  + + +          
Sbjct: 668  QNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQ 727

Query: 171  --LASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQK 228
                +Q  +MP G    ++   P+ Q   V         +  +    +    Q+ G   +
Sbjct: 728  FNTQNQSNVMP-GPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQ 786

Query: 229  AI-PPGASPVSSLSQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIP-------GSMG 280
             + PPG SP  +         A    S       +++ Q      N +P       G+  
Sbjct: 787  VLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQT-----NMVPPHVQAMQGNSA 841

Query: 281  PGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQTVT-----------VSQG--- 326
             G     HG     P SG   G+    G     P+    T+T           +S G   
Sbjct: 842  SGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFG 901

Query: 327  -----SQTEAESAAAKKA-EADGSGQQNVGMNLTRTA-------TPAPSQTLISSAT--- 370
                 + T A     KK      + QQ++    TR A        P P +  I+      
Sbjct: 902  VNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGP 961

Query: 371  ----YTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQ 426
                ++   P    Q  +Q  LQQ    + Q +A   Q   Q  Q QL         +Q 
Sbjct: 962  KLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQP 1021

Query: 427  QQQQQQQQQQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLP- 485
            Q QQQQQQQQQ          P+  ++P +Q V P +      +  + PM QS  + +  
Sbjct: 1022 QSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRM-PMQQSGSVPVMV 1080

Query: 486  --PDAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQAL 543
                 A  PP P + + P+ P+  P LG+       Q  P  P               + 
Sbjct: 1081 SLQGPASVPPSPDKQRMPM-PVNTP-LGSNSRKMVYQESPQNP--------------SSS 1124

Query: 544  GLAQLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAH 603
             LA++A+    S     +V  G  ++ S     Q    L    P   P    +P+  T  
Sbjct: 1125 PLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQ--NQLMMTGPKPGP----SPLSATQ- 1177

Query: 604  VVKGGATTSSPVVAQVPAAFYMQSVHLPGKPQTLAVKRKADSEEERDDVSTLGSMLPAKA 663
                GAT   P V  +P++      ++    QT   K                   P +A
Sbjct: 1178 ----GATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPK------------------TPNRA 1215

Query: 664  SPVAESPKVMDEKSSLGEKAE---SVANVNANT----PSSELVALTPAPS---------V 707
            SP    P+  + +    E +E   S   +NA+     P    + L P P+         +
Sbjct: 1216 SPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGL 1275

Query: 708  PPPTLAMVSRQMGD-SKPPQAIVKPQILTHIIEGFVIQEGAE 748
             P TL  + +   + +  P     PQ  TH ++  V+  G +
Sbjct: 1276 NPTTLKAIGQAPSNLTMNPSNFATPQ--THKLDSVVVNSGKQ 1315



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 121/574 (21%), Positives = 185/574 (32%), Gaps = 96/574 (16%)

Query: 187 QQEVPSAQSPGVHADADQVQNLAVR----NQQASAQG--PQMQGSTQKAIPPGASPVSSL 240
           QQ+    Q         Q Q L  R    +QQ   QG  PQ    TQ  +PPG +     
Sbjct: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWN----- 319

Query: 241 SQASSQALAVAQASSGATNQSLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG 300
                      Q  SGA                  P + G  G   A+ G  + P  G  
Sbjct: 320 -----------QLPSGALQP---------------PPAQGSLGTMTANQGWKKAPLPGPM 353

Query: 301 GGSCPRKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPA 360
                 + +      P+        GSQ +A  A     +    GQ       +    P+
Sbjct: 354 QQQLQARPSLATVQTPSHPPPPYPFGSQ-QASQAHTNFPQMSNPGQFTAPQMKSLQGGPS 412

Query: 361 PSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATH 420
              T +     T   P S     QQ        V Q                      T 
Sbjct: 413 RVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQ----------------------TQ 450

Query: 421 LQLAQQQQQQQQQQQQQQQPQATTLTAP--QPPQVPPT----QQVPPSQSQQQAQTLVVQ 474
            Q+  +  Q     Q  QQP ++    P  Q   VPP     QQ PP+Q  Q      + 
Sbjct: 451 QQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQS-----LH 505

Query: 475 PMLQSSPLSLPP--DAAPKPPIPIQSK-PPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVG 531
           P L   P  LPP   A    P  +Q + P      P   GA ++ A Q       VQ  G
Sbjct: 506 PGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQN------VQHAG 559

Query: 532 TRQPGTAQAQ-ALGLAQLAAAVPTSRGMPGTVQSGQAHLASSPP--SSQAPGALQECPPT 588
            +  G  Q Q  +         P+  G+ G + + QA  +  P    S   G  Q+ PP+
Sbjct: 560 GQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPS 619

Query: 589 LAPGM--TLAPVQGTAHVVKGGATTSSPVV---AQVPAAFYMQ----SVHLPGKPQTLAV 639
              GM   + P QG     +G     +P++   AQ+     M     S +L   PQ +  
Sbjct: 620 QLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTP 679

Query: 640 KRKADSEEERDDVSTLGSMLPAKASPVAES----PKVMDEKSSLGEKAESVANVNANTPS 695
            ++  S++    ++    M+  +   + +      ++M  +    ++  +  N +   P 
Sbjct: 680 PKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG 739

Query: 696 SELVALTPAPSVPPPTLAMVSRQMGDSKPPQAIV 729
              +   P P++    +    +  G   P Q  V
Sbjct: 740 PAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV 773



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 92/409 (22%), Positives = 149/409 (36%), Gaps = 75/409 (18%)

Query: 430  QQQQQQQQQQPQATTLTAPQ--PPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPD 487
            Q Q      +P  + L+A Q   PQ PP   +P S         V  P   S P + P  
Sbjct: 1158 QNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPN--VAAPTQTSRPKT-PNR 1214

Query: 488  AAPKPPIPI-------QSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVV-------GTR 533
            A+P+P  P         ++P    + P +L A   S A   PP I + +        G  
Sbjct: 1215 ASPRPYYPQTPNNRPPSTEPSEISLSPERLNA---SIAGLFPPQINIPLPPRPNLNRGFD 1271

Query: 534  QPGTAQAQALGLAQLAAAV---PTSRGMPGT-------VQSGQ-----AHLASSPPSSQ- 577
            Q G        + Q  + +   P++   P T       V SG+     A   +SP +S+ 
Sbjct: 1272 QQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRR 1331

Query: 578  -APGALQECPPT------LAPGMTLAPVQGTAHVVKGGATTSSPVVAQVPAAFYMQSVHL 630
             +PG+ ++  P+       AP +TLA  Q  A +++      + +V+  P A        
Sbjct: 1332 SSPGSSRKTTPSPGRQNSKAPKLTLAS-QTNAALLQNVELPRNVLVSPTPLAN------- 1383

Query: 631  PGKPQTLAVKRKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVN 690
            P  P +       + +     V+ +G +             V D K SL    +S    +
Sbjct: 1384 PPVPGSFPNNSGLNPQNSTVSVAAVGGV-------------VEDNKESLNVPQDSDCQNS 1430

Query: 691  ANTPSSELVALTPAPSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGF-VIQEGAEP 749
             +      + L   P+     +    +   D +P      P  L  + E   ++      
Sbjct: 1431 QSRKEQVNIELKAVPAQEVKMVVPEDQSKKDGQPSD----PNKLPSVEENKNLVSPAMRE 1486

Query: 750  FPVGCSQLLKESEKPLQTGLPTGLTENQSGGPLGVDSPSAELDKKANLL 798
             P   SQLL  S  P  T  P GLT+ +   P+     S E  KKA+++
Sbjct: 1487 APTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPV----VSGEDLKKASVI 1531



 Score = 35.4 bits (80), Expect = 0.27
 Identities = 82/341 (24%), Positives = 130/341 (38%), Gaps = 65/341 (19%)

Query: 438  QQPQATTLTAPQPPQVPPTQQVP---PSQSQQQAQTLVVQPMLQSSP--------LSLPP 486
            Q P     ++P  P  PP QQV    P ++  Q  T   Q  L SS         L+  P
Sbjct: 1742 QLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSP 1801

Query: 487  DAAPKPPIPIQSKPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLA 546
             ++     P+ S       K  ++G   ++ A +       +V G+ + G  Q  A G  
Sbjct: 1802 GSSGNRRSPVSSSKGKG--KVDKIGQILLTKACK-------KVTGSLEKGEEQYGADGET 1852

Query: 547  QLAAAVPTSRGMPGTVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLA----PVQGTA 602
            +      T+ G+ GT Q     L S  P+  AP  L+     + PG   A    P     
Sbjct: 1853 EGQGLDTTAPGLMGTEQL-STELDSKTPTPPAPTLLKMTSSPVGPGTASAGPSLPGGALP 1911

Query: 603  HVVKGGATTSSP--VVAQVPAAFYMQSVHLPGKPQTLA---VKRKADSEEERDDVSTLGS 657
              V+   TT  P  +++ VP     +S H     ++LA   V+ K  S  E         
Sbjct: 1912 TSVRSIVTTLVPSELISAVPTT---KSNHGGIASESLAGGLVEEKVGSHPE--------- 1959

Query: 658  MLPAKASPVAESPKVMDEKSSLGEKAESVA----NVNA---NTPSSELVALTPAPSVP-- 708
            +LP+    +A S  ++ +++S      SVA     VNA   +  SSE   +     +P  
Sbjct: 1960 LLPS----IAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGR 2015

Query: 709  ------PPTLAMVSRQMG----DSKPPQAIVKPQILTHIIE 739
                   PT+A  S + G     S+P  A    + +T  ++
Sbjct: 2016 RNSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQ 2056



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 57/262 (21%), Positives = 95/262 (36%), Gaps = 60/262 (22%)

Query: 170  PLASQLILMPNGAVAAVQQEVPSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKA 229
            P  S  ++  +  V  V++  P   SP V+  ADQ  N    +Q  +   P +  S    
Sbjct: 1747 PCTSSPVVPSHPPVQQVKELNPDEASPQVNTSADQ--NTLPSSQSTTMVSPLLTNS---- 1800

Query: 230  IPPGAS-----PVSSLSQASSQALAVAQA-------------SSGATNQSLNLSQAGGGS 271
              PG+S     PVSS S+   +   + Q                G      +    G G 
Sbjct: 1801 --PGSSGNRRSPVSS-SKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGL 1857

Query: 272  GNSIPGSMG--------------------------PGGGGQAHGGLGQLPSSGMGGGSCP 305
              + PG MG                          P G G A  G    PS  + GG+ P
Sbjct: 1858 DTTAPGLMGTEQLSTELDSKTPTPPAPTLLKMTSSPVGPGTASAG----PS--LPGGALP 1911

Query: 306  RKGTGVVQPLPAAQTVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTL 365
                 +V  L  ++ ++    +++      A ++ A G  ++ VG +     + APSQ L
Sbjct: 1912 TSVRSIVTTLVPSELISAVPTTKSN-HGGIASESLAGGLVEEKVGSHPELLPSIAPSQNL 1970

Query: 366  ISSATYTQIQPHSLIQQQQQIH 387
            +S  T T     S+ + + +++
Sbjct: 1971 VSKETSTTALQASVARPELEVN 1992



 Score = 34.3 bits (77), Expect = 0.60
 Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 17/140 (12%)

Query: 446  TAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSPLSLPPDAAPKPPIP-IQSKPPV-- 502
            T P  P    +  +PPS +      L +   ++ S   +PP+A    P P IQ+  P+  
Sbjct: 1677 TIPAAPLTTNSGLMPPSVAV--VGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVL 1734

Query: 503  -APIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGT 561
             +   P QL +   +++   P H PVQ V    P  A  Q          V TS     T
Sbjct: 1735 SSRATPVQLPSPPCTSSPVVPSHPPVQQVKELNPDEASPQ----------VNTSADQ-NT 1783

Query: 562  VQSGQAHLASSPPSSQAPGA 581
            + S Q+    SP  + +PG+
Sbjct: 1784 LPSSQSTTMVSPLLTNSPGS 1803


>gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens]
          Length = 1073

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 142/617 (23%), Positives = 217/617 (35%), Gaps = 93/617 (15%)

Query: 191 PSAQSPGVHADADQVQNLAVRNQQASAQGPQMQGSTQKA-IPPGASPVSSLSQASSQALA 249
           P ++       +D +  +A  +  +S+  P    +  +A    G   ++S++  +S    
Sbjct: 257 PVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIGINSVT-GTSTVNN 315

Query: 250 VAQASSGATNQSLNLSQAGGG--SGNSIPGSMGPGGGGQAHGGLGQLPSSGMGGGSCPRK 307
           V   + G+ N ++  S  G    S ++IP + G   G     G+     SGMG G+    
Sbjct: 316 VNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSS 375

Query: 308 GTGVVQPLPAAQTV---TVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRT-------A 357
                 P  AA        SQ  Q    ++  +  + D S +       T T       A
Sbjct: 376 AAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENA 435

Query: 358 TPAPSQTLISSATYTQIQPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHT 417
            PA    LI+    T ++ + +    ++       V        H+ +     +      
Sbjct: 436 VPATEGVLINKVVET-VKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEM----- 489

Query: 418 ATHLQLAQQQQQQQQQQQQQQQPQATTLT----APQPPQVPPTQQVPPSQSQQQAQTLVV 473
                + QQQQQQQQQQQQQ   Q  TL         PQ  P   +P S SQ Q    + 
Sbjct: 490 GAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQ----IS 545

Query: 474 QPMLQSSPLSLPPDAAPKPPIPIQSKPPVAP-IKPPQLGAAKMSAA--QQP------PPH 524
           Q  LQS  LS       + P+P+Q+    A  I+P  +    +++A  QQP       P 
Sbjct: 546 QVQLQSQELSYQQKQGLQ-PVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQ 604

Query: 525 IP----VQVVGTRQPGTAQAQALGLAQLAAAVPTSRGMPGTVQSG--------------- 565
           +P       V T  PG    Q L   Q    V T    PG V+S                
Sbjct: 605 LPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMA-PGHVKSVTQNPASEYVQQQPIL 663

Query: 566 QAHLASSPPSSQAPGALQECPPTLAPGMTLAPVQGTAHVVKGGATTSSPV---------- 615
           Q  ++S  PSS   GA     P   P     PVQ TA   +    +  PV          
Sbjct: 664 QTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAV 723

Query: 616 -----------VAQVPAAFYMQSVHLP------GKPQTLAVKRKADSEEERDDVSTLGSM 658
                       A +P A    S  +P      G P +  V   A +      V T    
Sbjct: 724 PTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPS 783

Query: 659 LPAKASPVAESPKVMDEKSSLGEKAESVANVNANTPSSELVALTPAPSVPPPTLAMVSRQ 718
           LP +    ++S  +     ++  + + V  V     S +L A++  PS    ++      
Sbjct: 784 LPQQLVIASQSSLL-----TVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSS 838

Query: 719 MGDSKPPQA---IVKPQ 732
            G S  P A   +V PQ
Sbjct: 839 TGPSGMPSAPTNLVPPQ 855



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 174/820 (21%), Positives = 292/820 (35%), Gaps = 136/820 (16%)

Query: 76   ATIAASRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLG 135
            A  +A   + SP +  T  +  +T   I + + +    ++     +  S      S +LG
Sbjct: 275  APTSAVSSSGSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLG 334

Query: 136  NTTSPPLN-QSQAQMYLRPQLGNLLQVNRTLGRN---VPLASQLILMPNGAVAAVQQEVP 191
            N      N  S A + + P + + + VN   G     +  ++ +  +PN A       V 
Sbjct: 335  NVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVS 394

Query: 192  SAQS-PGVHADADQVQNLAVRNQQASAQGPQMQG--------STQKAIPPGASP-----V 237
            S Q  P V+    +V  L       S+  P  +G          + A+P          V
Sbjct: 395  SQQQQPTVNTSRFRVVKLD------SSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVV 448

Query: 238  SSLSQASSQALAVAQASSGATNQSL--NLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLP 295
             ++ Q   +  +  +++SG++  S    LS      G+   G+       Q      Q  
Sbjct: 449  ETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQ 508

Query: 296  SSGMGGGSCPRKGTGVVQP--LPAA---QTVTVSQGSQTEAESAAAKKAEADGSGQQNVG 350
               + G +  +   G   P  +PA    Q+++ SQ SQ + +S      +  G   Q V 
Sbjct: 509  QPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGL--QPVP 566

Query: 351  MNLTRTAT----PAPSQTL-ISSATYTQIQPHSLIQQQ--------------------QQ 385
            +  T +A     P+P   + ++SA   Q    SL Q Q                    QQ
Sbjct: 567  LQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQ 626

Query: 386  IHLQQKQVVIQQQIAIHHQQQF-QHRQSQLLHTATHLQLAQQQQQQQQ------------ 432
            +   Q+Q ++  Q+A  H +   Q+  S+ +     LQ A    Q               
Sbjct: 627  LQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPV 686

Query: 433  -QQQQQQQPQATTLTAPQPP--QVPPTQQVPPSQSQQQAQTLVVQPMLQSS-PLSLPPDA 488
             Q Q  Q P   T    QP    V P  Q P + S     + +     Q++ P ++   +
Sbjct: 687  AQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPS 746

Query: 489  APKPPIPIQS-KPPVAPIKPPQLGAAKMSAAQQPPPHIPVQVVGTRQPG--TAQAQALGL 545
               PP  IQ   PP + + PP          Q   P +P Q+V   Q    T   Q  G+
Sbjct: 747  TQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGV 806

Query: 546  AQLAAAVPTSRGMPG--TVQSGQAHLASSPPSSQAPGALQECPPTLAPGMTLA--PVQGT 601
              +A  +  S+ +P   ++ S  +   +S  SS  P  +   P  L P   +A  P    
Sbjct: 807  EPVAQGI-VSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQN 865

Query: 602  AHVVKG-------GATTSSPVVAQVPAA---FYMQSV-----------------HLPGKP 634
             ++V+           T+ P+  Q+P +   F  QS+                  L G P
Sbjct: 866  GNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLP 925

Query: 635  QTLAVK---RKADSEEERDDVSTLGSMLPAKASPVAESPKVMDEKSSLGEKAESVANVNA 691
            QT++       A S+     ++   S+ P K  P+       +++SS G  A  VA  N 
Sbjct: 926  QTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSG--ASVVAIDNK 983

Query: 692  NTPSSELVALTPAPSVPPPTLAMVSRQMGDSKPPQAIVKPQILTHIIEGFVI-QEGAEPF 750
               + +LV                S  M   +    ++K QI   I +   + QE     
Sbjct: 984  IEQAMDLVK---------------SHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLK 1028

Query: 751  PVGCSQLLKESEKPLQTGLPTGLTENQSGGPLGVDSPSAE 790
             +   + L + +  LQTG P   T+     P G   P A+
Sbjct: 1029 TLASPEQLAQFQAQLQTGSPPATTQ-----PQGTTQPPAQ 1063



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 98/451 (21%), Positives = 168/451 (37%), Gaps = 51/451 (11%)

Query: 40   LQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAASRQASSPN-----TSTTQQ 94
            ++++ + P +     Q +LQ  +S+ Q  S       T+    Q          T+   Q
Sbjct: 645  VKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQ 704

Query: 95   QTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSPPLNQSQ-----AQM 149
                +   +  A  + + + + SQ  +      +  +V   +T  PP    Q     +Q+
Sbjct: 705  PAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQV 764

Query: 150  YLRPQLGNLLQVNRTLGRNVP----LASQLILM-----PNGAVAAVQQEVPSAQSPGVHA 200
                Q G + Q  +T   ++P    +ASQ  L+     P G V  V Q + S Q P V +
Sbjct: 765  VPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQG-VEPVAQGIVSQQLPAV-S 822

Query: 201  DADQVQNLAVRNQQASAQGPQMQGSTQKAIPPGASPVSSLSQASSQALAVAQASSGATNQ 260
                  +++V +Q +S     M  +    +PP     +  +Q  +   +V+Q    ATN 
Sbjct: 823  SLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNT 882

Query: 261  SLNLSQAGGGSGNSIPG-SMGPGGGGQAHGGLGQLPSSGMGGGSCPRKGTGVVQPLPAAQ 319
            +L L+Q    S       S+    G Q          S +G              LP  Q
Sbjct: 883  NLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVG--------------LP--Q 926

Query: 320  TVTVSQGSQTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQI----- 374
            T++   G  +     ++    A  S      + LT        ++  S A+   I     
Sbjct: 927  TISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDES-SSGASVVAIDNKIE 985

Query: 375  QPHSLIQQQQQIHLQQKQVVIQQQI--AIHHQQQFQHRQSQLLHTATHLQLAQ-QQQQQQ 431
            Q   L++      ++++  V+++QI   I    Q +   + L   A+  QLAQ Q Q Q 
Sbjct: 986  QAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQT 1045

Query: 432  QQQQQQQQPQATTLTAPQPPQVPPTQQVPPS 462
                   QPQ TT    QPP  P +Q   P+
Sbjct: 1046 GSPPATTQPQGTT----QPPAQPASQGSGPT 1072



 Score = 30.4 bits (67), Expect = 8.7
 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 14/124 (11%)

Query: 21  SSRPQIAQMSLYERQAVQALQALQRQPNAAQYFHQFMLQQQLSNAQLHSLAAVQQATIAA 80
           +S P + Q  +   Q+  +L  +  QP   +   Q ++ QQL    + SL +   ++I+ 
Sbjct: 779 TSAPSLPQQLVIASQS--SLLTVPPQPQGVEPVAQGIVSQQLP--AVSSLPSA--SSISV 832

Query: 81  SRQASSPNTSTTQQQTTTTQASINLATTSAAQLISRSQSVSSPSATTLTQSVLLGNTTSP 140
           + Q SS   S      T      N+A T A Q  +  QSVS P         L+   T+ 
Sbjct: 833 TSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPP--------LIATNTNL 884

Query: 141 PLNQ 144
           PL Q
Sbjct: 885 PLAQ 888


>gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens]
          Length = 681

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 31/61 (50%), Positives = 43/61 (70%)

Query: 938 SRWSVEEVYEFIASLQGCQEIAEEFRSQEIDGQALLLLKEEHLMSAMNIKLGPALKICAK 997
           ++W+V++V  F+  L GC E    FR Q IDG+ L LL EEHL++ M +KLGPALKI A+
Sbjct: 541 TKWTVDDVCSFVGGLSGCGEYTRVFREQGIDGETLPLLTEEHLLTNMGLKLGPALKIRAQ 600

Query: 998 I 998
           +
Sbjct: 601 V 601


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.123    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,902,132
Number of Sequences: 37866
Number of extensions: 2407817
Number of successful extensions: 38689
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 480
Number of HSP's successfully gapped in prelim test: 1374
Number of HSP's that attempted gapping in prelim test: 15665
Number of HSP's gapped (non-prelim): 11311
length of query: 1004
length of database: 18,247,518
effective HSP length: 112
effective length of query: 892
effective length of database: 14,006,526
effective search space: 12493821192
effective search space used: 12493821192
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.