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Search of human proteins with 62899065
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62899065 centrosomal protein 72 kDa [Homo sapiens]
(647 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62899065 centrosomal protein 72 kDa [Homo sapiens] 1283 0.0
gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo s... 137 3e-32
gi|239735598 leucine rich repeat containing 36 isoform 2 [Homo s... 68 2e-11
gi|4826651 hypothetical protein LOC755 [Homo sapiens] 56 1e-07
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 52 1e-06
gi|157674358 leucine rich repeat containing 50 [Homo sapiens] 51 4e-06
gi|239752518 PREDICTED: similar to leucine rich repeat containin... 48 2e-05
gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 48 2e-05
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 48 3e-05
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 48 3e-05
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap... 48 3e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 48 3e-05
gi|239754500 PREDICTED: Leucine-rich repeat-containing protein E... 47 4e-05
gi|239749060 PREDICTED: Leucine-rich repeat-containing protein E... 47 4e-05
gi|239743086 PREDICTED: Leucine-rich repeat-containing protein E... 47 4e-05
gi|239508737 PREDICTED: Leucine-rich repeat-containing protein E... 47 4e-05
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 47 4e-05
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 47 4e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 47 5e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 47 5e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 47 5e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 47 5e-05
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s... 47 5e-05
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s... 47 5e-05
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s... 47 5e-05
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s... 47 5e-05
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 47 7e-05
gi|34577114 cytomatrix protein p110 [Homo sapiens] 46 9e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 46 1e-04
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 45 2e-04
>gi|62899065 centrosomal protein 72 kDa [Homo sapiens]
Length = 647
Score = 1283 bits (3321), Expect = 0.0
Identities = 647/647 (100%), Positives = 647/647 (100%)
Query: 1 MARAGPRLVLSEEAVRAKSGLGPHRDLAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLD 60
MARAGPRLVLSEEAVRAKSGLGPHRDLAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLD
Sbjct: 1 MARAGPRLVLSEEAVRAKSGLGPHRDLAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLD 60
Query: 61 LSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPVVKVEPDY 120
LSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPVVKVEPDY
Sbjct: 61 LSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPVVKVEPDY 120
Query: 121 RLFVVHLLPKLQQLDDRPVRASERKASRLHFASEDSLDSKESVPASLKEGRPHHPRAKCT 180
RLFVVHLLPKLQQLDDRPVRASERKASRLHFASEDSLDSKESVPASLKEGRPHHPRAKCT
Sbjct: 121 RLFVVHLLPKLQQLDDRPVRASERKASRLHFASEDSLDSKESVPASLKEGRPHHPRAKCT 180
Query: 181 EALAKQSLVMDADDEAVLNLIAECEWDLGRPPGSTSFSQKGREADSRGSQESRHLLSPQL 240
EALAKQSLVMDADDEAVLNLIAECEWDLGRPPGSTSFSQKGREADSRGSQESRHLLSPQL
Sbjct: 181 EALAKQSLVMDADDEAVLNLIAECEWDLGRPPGSTSFSQKGREADSRGSQESRHLLSPQL 240
Query: 241 VQYQCGDSGKQGRETRRSSCRGCCLEKMPWSQLCGELPPLYGAEPEASRAPRPHTYFTPH 300
VQYQCGDSGKQGRETRRSSCRGCCLEKMPWSQLCGELPPLYGAEPEASRAPRPHTYFTPH
Sbjct: 241 VQYQCGDSGKQGRETRRSSCRGCCLEKMPWSQLCGELPPLYGAEPEASRAPRPHTYFTPH 300
Query: 301 PDSMDTEDSASSQKLDLSGEMVPGPLPAPGKCRKRRMPVGRFQTFSDQEGLGCPERTHGS 360
PDSMDTEDSASSQKLDLSGEMVPGPLPAPGKCRKRRMPVGRFQTFSDQEGLGCPERTHGS
Sbjct: 301 PDSMDTEDSASSQKLDLSGEMVPGPLPAPGKCRKRRMPVGRFQTFSDQEGLGCPERTHGS 360
Query: 361 SVPKESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQA 420
SVPKESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQA
Sbjct: 361 SVPKESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQA 420
Query: 421 ALLETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALE 480
ALLETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALE
Sbjct: 421 ALLETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALE 480
Query: 481 SKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKE 540
SKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKE
Sbjct: 481 SKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKE 540
Query: 541 VKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNE 600
VKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNE
Sbjct: 541 VKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNE 600
Query: 601 HLLQELSQVRAQHRAEVEQMHWSYQELKKTMALFPHSSASHGGCQAC 647
HLLQELSQVRAQHRAEVEQMHWSYQELKKTMALFPHSSASHGGCQAC
Sbjct: 601 HLLQELSQVRAQHRAEVEQMHWSYQELKKTMALFPHSSASHGGCQAC 647
>gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo
sapiens]
Length = 754
Score = 137 bits (345), Expect = 3e-32
Identities = 183/698 (26%), Positives = 279/698 (39%), Gaps = 88/698 (12%)
Query: 10 LSEEAVRAKSGLGPHRDLAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSL 69
L EE +R L + ++SLS+ G+Y KI +G + + L+SLDLSRN + SL
Sbjct: 7 LDEEGIRRLGALTLEQPEL-VESLSLQGSYAGKIHSIGDAFRNFKNLRSLDLSRNLITSL 65
Query: 70 EGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLP 129
+GIQYL +L+ LNLYYN I SL EV RL L L ++D RLNPVV+ + DYRLF V+ L
Sbjct: 66 KGIQYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNPVVRKDTDYRLFAVYTLQ 125
Query: 130 KLQQLDDRPVRASERKASRLHFASEDSLDSKESVPASLKEGRPHHPRAKCTEALAKQSLV 189
L++LDDR VR ERKA++LHF+ L + E+ +++ C + S V
Sbjct: 126 TLEKLDDRTVREGERKAAKLHFS---QLGNSENFLLEVEKSSREKTMKNCVTGESSASKV 182
Query: 190 MDADDEAVLNLIAECEWDLG----------RPPGSTSFSQKGREADSRGSQESRHLLSPQ 239
D + E + + G + STS +Q D + + +
Sbjct: 183 SANVDSRI-----EMDSNKGLFIPFPNREIKDSLSTSATQGNGTRDQKLDTFPLGTQTQE 237
Query: 240 LVQYQCGDSGKQGRETRRSSCRGCCL---EKMPWS--QLCGELPPLYGAEPEASRAPRPH 294
+ + + Q E R S R + EKM Q+ G+ PE P+P
Sbjct: 238 VARREMPSDNHQEDEFRHYSPRQSTVRSPEKMTREGYQVSFLDNKSSGSSPEKELIPKPD 297
Query: 295 TYFTPHPDS----MDTEDSASSQKLDLSGEM--------VPGPLPAPGKCRKRRMPVGRF 342
T+ H S +D DS+ L ++ L G KR +
Sbjct: 298 TFHLTHDASLSKCLDVGDSSQIHPYQLPSDVGLENYDSCYSQTLSLHGSLGKRPQRSKNY 357
Query: 343 QTFSDQEGLGC-PERTHGSSVPKESLSRQDSSESR----------NGRTLSQPEASETEE 391
Q +S + +H SLS DSS R S P E
Sbjct: 358 QEYSIKPSNDIKTTASHSCGDLLTSLSNPDSSTGRLLKLSSDLYATTHFNSDPAVLVNVE 417
Query: 392 QRSRGVTDTREPSPGS--HSALPGKKTALQAALLETLLDLVDRSWGGCRSLHSNEAFLAQ 449
Q+ D P+ GS ++A+ G +T LL + R RSL ++
Sbjct: 418 QQLSTSLDDLTPAHGSVPNNAVLGNRTTPLRTLLLSPGTSEHRKIFTKRSLSPSKRGFKW 477
Query: 450 ARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHT 509
+IL+++ QD++ S+ L S L ++A H
Sbjct: 478 KDNILANLNLKHGFQDATG------------SEPLSSDLGSLHGLAGNHSPPISARTPHV 525
Query: 510 HKELDDLRQHLDKSLEENSRL----------KSLLLSMKKEVKS--------ADTAATLN 551
L L + +DK + L + LLLS+ S DT
Sbjct: 526 ATVLRQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPSQPRCCSHPEDTMKAFC 585
Query: 552 LQIAGLQTSVKRLCGEIVELKQH----LEHYDKIQELTQMLQESHS-SLVSTNE-HLLQE 605
+ L+ + + + ++ LKQ LE + E Q L+E + S+VS + H +
Sbjct: 586 RRELELKEAAQLVPNDMESLKQKLVRVLEENLILSEKIQQLEEGAAISIVSGQQSHTYDD 645
Query: 606 LSQVRAQHRAEVEQMHWSYQELK---KTMALFPHSSAS 640
L Q +V ++ +LK KT+A+ S S
Sbjct: 646 LLHKNQQLTMQVACLNQELAQLKKLEKTVAILHESQRS 683
Score = 68.2 bits (165), Expect = 2e-11
Identities = 56/211 (26%), Positives = 96/211 (45%), Gaps = 33/211 (15%)
Query: 406 GSHSALPGKKTALQAALLETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQD 465
G+HS +T A +L LL+LVD+ W G SL N+ FL AR +L S+ +Q
Sbjct: 512 GNHSPPISARTPHVATVLRQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPSQP 571
Query: 466 SSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLE 525
ED + R E+ +++ L+Q L + LE
Sbjct: 572 RCCSHPEDT-----------------MKAFCRRELELKEAAQLVPNDMESLKQKLVRVLE 614
Query: 526 ENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSV--------KRLCGEIVELKQHLEH 577
EN L + ++++ + A +++ ++G Q+ ++L ++ L Q L
Sbjct: 615 EN-------LILSEKIQQLEEGAAISI-VSGQQSHTYDDLLHKNQQLTMQVACLNQELAQ 666
Query: 578 YDKIQELTQMLQESHSSLVSTNEHLLQELSQ 608
K+++ +L ES SLV TNE+LLQ+L++
Sbjct: 667 LKKLEKTVAILHESQRSLVVTNEYLLQQLNK 697
>gi|239735598 leucine rich repeat containing 36 isoform 2 [Homo
sapiens]
Length = 633
Score = 68.2 bits (165), Expect = 2e-11
Identities = 56/211 (26%), Positives = 96/211 (45%), Gaps = 33/211 (15%)
Query: 406 GSHSALPGKKTALQAALLETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQD 465
G+HS +T A +L LL+LVD+ W G SL N+ FL AR +L S+ +Q
Sbjct: 391 GNHSPPISARTPHVATVLRQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPSQP 450
Query: 466 SSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLE 525
ED + R E+ +++ L+Q L + LE
Sbjct: 451 RCCSHPEDT-----------------MKAFCRRELELKEAAQLVPNDMESLKQKLVRVLE 493
Query: 526 ENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSV--------KRLCGEIVELKQHLEH 577
EN L + ++++ + A +++ ++G Q+ ++L ++ L Q L
Sbjct: 494 EN-------LILSEKIQQLEEGAAISI-VSGQQSHTYDDLLHKNQQLTMQVACLNQELAQ 545
Query: 578 YDKIQELTQMLQESHSSLVSTNEHLLQELSQ 608
K+++ +L ES SLV TNE+LLQ+L++
Sbjct: 546 LKKLEKTVAILHESQRSLVVTNEYLLQQLNK 576
Score = 36.6 bits (83), Expect = 0.074
Identities = 125/581 (21%), Positives = 201/581 (34%), Gaps = 87/581 (14%)
Query: 127 LLPKLQQLDDRPVRASERKASRLHFASEDSLDSKESVPASLKEGRPHHPRAKCTEALAKQ 186
L P+ DDR VR ERKA++LHF+ L + E+ +++ C +
Sbjct: 2 LRPRFLPPDDRTVREGERKAAKLHFS---QLGNSENFLLEVEKSSREKTMKNCVTGESSA 58
Query: 187 SLVMDADDEAVLNLIAECEWDLG----------RPPGSTSFSQKGREADSRGSQESRHLL 236
S V D + E + + G + STS +Q D +
Sbjct: 59 SKVSANVDSRI-----EMDSNKGLFIPFPNREIKDSLSTSATQGNGTRDQKLDTFPLGTQ 113
Query: 237 SPQLVQYQCGDSGKQGRETRRSSCRGCCL---EKMPWS--QLCGELPPLYGAEPEASRAP 291
+ ++ + + Q E R S R + EKM Q+ G+ PE P
Sbjct: 114 TQEVARREMPSDNHQEDEFRHYSPRQSTVRSPEKMTREGYQVSFLDNKSSGSSPEKELIP 173
Query: 292 RPHTYFTPHPDS----MDTEDSASSQKLDLSGEM--------VPGPLPAPGKCRKRRMPV 339
+P T+ H S +D DS+ L ++ L G KR
Sbjct: 174 KPDTFHLTHDASLSKCLDVGDSSQIHPYQLPSDVGLENYDSCYSQTLSLHGSLGKRPQRS 233
Query: 340 GRFQTFSDQEGLGC-PERTHGSSVPKESLSRQDSSESR----------NGRTLSQPEASE 388
+Q +S + +H SLS DSS R S P
Sbjct: 234 KNYQEYSIKPSNDIKTTASHSCGDLLTSLSNPDSSTGRLLKLSSDLYATTHFNSDPAVLV 293
Query: 389 TEEQRSRGVTDTREPSPGS--HSALPGKKTALQAALLETLLDLVDRSWGGCRSLHSNEAF 446
EQ+ D P+ GS ++A+ G +T LL + R RSL ++
Sbjct: 294 NVEQQLSTSLDDLTPAHGSVPNNAVLGNRTTPLRTLLLSPGTSEHRKIFTKRSLSPSKRG 353
Query: 447 LAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAEL 506
+IL+++ QD++ S+ L S L ++A
Sbjct: 354 FKWKDNILANLNLKHGFQDATG------------SEPLSSDLGSLHGLAGNHSPPISART 401
Query: 507 HHTHKELDDLRQHLDKSLEENSRL----------KSLLLSMKKEVKS--------ADTAA 548
H L L + +DK + L + LLLS+ S DT
Sbjct: 402 PHVATVLRQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPSQPRCCSHPEDTMK 461
Query: 549 TLNLQIAGLQTSVKRLCGEIVELKQH----LEHYDKIQELTQMLQESHS-SLVSTNE-HL 602
+ L+ + + + ++ LKQ LE + E Q L+E + S+VS + H
Sbjct: 462 AFCRRELELKEAAQLVPNDMESLKQKLVRVLEENLILSEKIQQLEEGAAISIVSGQQSHT 521
Query: 603 LQELSQVRAQHRAEVEQMHWSYQELK---KTMALFPHSSAS 640
+L Q +V ++ +LK KT+A+ S S
Sbjct: 522 YDDLLHKNQQLTMQVACLNQELAQLKKLEKTVAILHESQRS 562
>gi|4826651 hypothetical protein LOC755 [Homo sapiens]
Length = 256
Score = 55.8 bits (133), Expect = 1e-07
Identities = 64/222 (28%), Positives = 101/222 (45%), Gaps = 22/222 (9%)
Query: 28 AELQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNC 87
+EL S+ + ++T + + L+ + LS NS+ +LE + L L L N
Sbjct: 15 SELHSVRKLNCWGSRLTDIS-ICQEMPSLEVITLSVNSISTLEPVSRCQRLSELYLRRNR 73
Query: 88 ISSLAEVFRLHALTELVDVDFRLNPVVKVEPD-YRLFVVHLLPKLQQLDDRPVRASERKA 146
I SLAE+F L L L + NP P YR+ V+ LP+LQ+LD++ V E
Sbjct: 74 IPSLAELFYLKGLPRLRVLWLAENPCCGTSPHRYRMTVLRTLPRLQKLDNQAVTEEE--- 130
Query: 147 SRLHFASEDSLDSKESVPASLKEGRPH-HPRAKCTEALAKQSL-----VMDADDEAVLNL 200
S + +E A +EG H P+ CT + + +D+++EA
Sbjct: 131 -----LSRALSEGEEITAAPEREGTGHGGPKLCCTLSSLSSAAETGRDPLDSEEEATSG- 184
Query: 201 IAECEWDLGRPPGSTSF-SQKGREADSRGSQESRHLLSPQLV 241
A+ E L +PP F S R+A S S R++L+ L+
Sbjct: 185 -AQDERGL-KPPSRGQFPSLSARDASS--SHRGRNVLTAILL 222
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 52.4 bits (124), Expect = 1e-06
Identities = 31/95 (32%), Positives = 55/95 (57%), Gaps = 1/95 (1%)
Query: 50 LMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFR 109
L L L++LDLS N + SL+G++ LE +NL N I+ L E+ + L L ++
Sbjct: 276 LEDLKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIAELREIEYIKNLPILRVLNLL 335
Query: 110 LNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRASER 144
NP ++ + +Y FV+ +L +L +LD + ++ E+
Sbjct: 336 ENP-IQEKSEYWFFVIFMLLRLTELDQKKIKVEEK 369
>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
Length = 725
Score = 50.8 bits (120), Expect = 4e-06
Identities = 65/249 (26%), Positives = 105/249 (42%), Gaps = 29/249 (11%)
Query: 8 LVLSEEAVRAKSGLGPHRDLAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLV 67
L L +R L P L +L +L++ Y + I +L L L +L ++ N L
Sbjct: 156 LFLQMNLLRKIENLEP---LQKLDALNLSNNYIKTIENLS----CLPVLNTLQMAHNHLE 208
Query: 68 SLEGIQYLTA---LESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPVVKVEPDYRLFV 124
++E IQ+L L L+L +N +S + L ++ +L ++ NPV++ P+YR V
Sbjct: 209 TVEDIQHLQECLRLCVLDLSHNKLSDPEILSILESMPDLRVLNLMGNPVIRQIPNYRRTV 268
Query: 125 VHLLPKLQQLDDRPVRASER--------------KASRLHFASEDSLDSKESVPASLKEG 170
L L LDDRPV +R K R + S + +S+ A
Sbjct: 269 TVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEERQQWESRERKKITDSIEALAMIK 328
Query: 171 RPHHPRAKCTEALAKQSLVMDADDEAVLNLIAECEWDLGRPPGSTSFSQKGREADSRGSQ 230
+ R + E+ + + D E N+ A E PPG QK E + S
Sbjct: 329 QRAEERKRQRESQERGEMTSSDDGE---NVPASAE-GKEEPPGDRETRQK-MELFVKESF 383
Query: 231 ESRHLLSPQ 239
E++ L P+
Sbjct: 384 EAKDELCPE 392
>gi|239752518 PREDICTED: similar to leucine rich repeat containing
50, partial [Homo sapiens]
Length = 489
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/143 (26%), Positives = 67/143 (46%), Gaps = 5/143 (3%)
Query: 27 LAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYN 86
L EL+ L++ + + +L L L L+L N + + + L L+ L L +N
Sbjct: 24 LCELRVLNLARNFLSHVDNLN----GLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFN 79
Query: 87 CISSLAEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRASERKA 146
ISS V L + L D+ F NP+ + E Y+ V+ + +L+QLD + + ER+
Sbjct: 80 NISSFDSVSCLADSSSLSDITFDGNPIAQ-ESWYKHTVLQNMMQLRQLDMKRITEEERRM 138
Query: 147 SRLHFASEDSLDSKESVPASLKE 169
+ + E+ + + LKE
Sbjct: 139 ASVLAKKEEEKKRESHKQSLLKE 161
Score = 33.5 bits (75), Expect = 0.63
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 9/81 (11%)
Query: 54 TGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPV 113
+ L LDL N + +E I +L L LNL N +S V L+ L L +++ R N +
Sbjct: 3 SNLDVLDLHGNQITKIENINHLCELRVLNLARNFLS---HVDNLNGLDSLTELNLRHNQI 59
Query: 114 VKVEPDYRLFVVHLLPKLQQL 134
V V LP LQ L
Sbjct: 60 TFVRD------VDNLPCLQHL 74
>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
Length = 686
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/143 (26%), Positives = 67/143 (46%), Gaps = 5/143 (3%)
Query: 27 LAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYN 86
L EL+ L++ + + +L L L L+L N + + + L L+ L L +N
Sbjct: 199 LCELRVLNLARNFLSHVDNLN----GLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFN 254
Query: 87 CISSLAEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRASERKA 146
ISS V L + L D+ F NP+ + E Y+ V+ + +L+QLD + + ER+
Sbjct: 255 NISSFDSVSCLADSSSLSDITFDGNPIAQ-ESWYKHTVLQNMMQLRQLDMKRITEEERRM 313
Query: 147 SRLHFASEDSLDSKESVPASLKE 169
+ + E+ + + LKE
Sbjct: 314 ASVLAKKEEEKKRESHKQSLLKE 336
Score = 35.8 bits (81), Expect = 0.13
Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 9/86 (10%)
Query: 49 SLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDF 108
+L +L L LDL N + +E I +L L LNL N +S V L+ L L +++
Sbjct: 173 NLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLS---HVDNLNGLDSLTELNL 229
Query: 109 RLNPVVKVEPDYRLFVVHLLPKLQQL 134
R N + V V LP LQ L
Sbjct: 230 RHNQITFVRD------VDNLPCLQHL 249
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 47.8 bits (112), Expect = 3e-05
Identities = 61/265 (23%), Positives = 113/265 (42%), Gaps = 23/265 (8%)
Query: 383 QPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQ---AALLETLLDLVD-RSWGGCR 438
+ E E EEQ +G + S H L +T L+ A +L+ + +L + R G
Sbjct: 24 EEEVEEEEEQVQKGGS-VGSLSVNKHRGLSLTETELEELRAQVLQLVAELEETRELAG-- 80
Query: 439 SLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHARE 498
H +++ Q L E +AQ + + + L E +SL+ ++ + + E
Sbjct: 81 -QHEDDSLELQG---LLEDERLASAQQAEVFT-KQIQQLQGELRSLREEISLLEHEKESE 135
Query: 499 MSEVTAELHHTHKELDDLRQHL-DKSLEENSRLKSL---LLSMKKEVKSAD-TAATLNLQ 553
+ E+ ELH E+ LRQ D + E S + SL L M+ E++ + ++
Sbjct: 136 LKEIEQELHLAQAEIQSLRQAAEDSATEHESDIASLQEDLCRMQNELEDMERIRGDYEME 195
Query: 554 IAGLQTSVKRLCGE---IVELKQHLEHYDKIQELTQ---MLQESHSSLVSTNEHLLQELS 607
IA L+ ++ E + L + +++QEL + L E + +L +N L +L+
Sbjct: 196 IASLRAEMEMKSSEPSGSLGLSDYSGLQEELQELRERYHFLNEEYRALQESNSSLTGQLA 255
Query: 608 QVRAQHRAEVEQMHWSYQELKKTMA 632
+ ++ + Q L T A
Sbjct: 256 DLESERTQRATERWLQSQTLSMTSA 280
Score = 35.8 bits (81), Expect = 0.13
Identities = 35/157 (22%), Positives = 70/157 (44%), Gaps = 11/157 (7%)
Query: 480 ESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKK 539
+++ L+SRL Q+++ E EL ++ L L + +KS L+ +
Sbjct: 363 QNEELKSRLCTLQKKYDTSQDE--------QNELLKMQLQLQTELRQLKVMKSTLVENQS 414
Query: 540 EVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLE-HYDKIQELTQMLQE-SHSSLVS 597
E + L+LQ + ++L +L++ L+ H ++Q L + S+
Sbjct: 415 EKELLCRLQKLHLQHQNVTCEKEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNEKD 474
Query: 598 TNEHL-LQELSQVRAQHRAEVEQMHWSYQELKKTMAL 633
T H LQE+ Q+ + E+E+ Y +L++ + L
Sbjct: 475 TETHAQLQEMKQLYQASKDELERQKHMYDQLEQDLLL 511
Score = 35.0 bits (79), Expect = 0.22
Identities = 34/152 (22%), Positives = 68/152 (44%), Gaps = 15/152 (9%)
Query: 466 SSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLE 525
+S + ED G A + +L SRL E Q+++ + KE+ L+ + LE
Sbjct: 521 ASHPIPEDKGKCANKCDTLLSRLTELQEKYKA-----------SQKEMGQLQMEQCELLE 569
Query: 526 ENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELT 585
+ R++ +++E+ TL L +GL + L ++ +L + Y +QE
Sbjct: 570 DQRRMQEEQGQLQEELHRL----TLPLPKSGLLLKSQELLTKLEDLCELQLLYQGMQEEQ 625
Query: 586 QMLQESHSSLVSTNEHLLQELSQVRAQHRAEV 617
+ L ++ ++ + +EL + + H EV
Sbjct: 626 KKLIQNQDCVLKEQLEIHEELRRFKESHFQEV 657
Score = 30.0 bits (66), Expect = 6.9
Identities = 35/155 (22%), Positives = 58/155 (37%), Gaps = 28/155 (18%)
Query: 485 QSRLAEQQQQHAREMSEVTAELHH-----------------THKELDDLRQHLDKSLEEN 527
+ +L E+QQQ E+ AEL H TH +L +++Q S +E
Sbjct: 436 KEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDEL 495
Query: 528 SRLKSL-------LLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDK 580
R K + LL + E+K + + L + EL+ E Y
Sbjct: 496 ERQKHMYDQLEQDLLLCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQ---EKYKA 552
Query: 581 IQELTQMLQESHSSLVSTNEHLLQELSQVRAQ-HR 614
Q+ LQ L+ + +E Q++ + HR
Sbjct: 553 SQKEMGQLQMEQCELLEDQRRMQEEQGQLQEELHR 587
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 47.8 bits (112), Expect = 3e-05
Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 28/185 (15%)
Query: 472 EDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLD----KSLEEN 527
+D+ S ES SRL EQ Q+ +E ++T EL K + + LD ++L+E
Sbjct: 385 DDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEK 444
Query: 528 SRLKSLL--LSMKKEVKSADTAATLNLQIAGLQTSVKR----LCGEIVELKQHLEHYDKI 581
S+ K L + ++ E + A ++ L KR L G+I E K + +
Sbjct: 445 SQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETL 504
Query: 582 QELTQMLQ------------------ESHSSLVSTNEHLLQELSQVRAQHRAEVEQMHWS 623
Q+ + LQ E+ SL + + L Q R QH AE++
Sbjct: 505 QQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEE 564
Query: 624 YQELK 628
Q+++
Sbjct: 565 LQDVR 569
Score = 44.7 bits (104), Expect = 3e-04
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 16/166 (9%)
Query: 482 KSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEV 541
+SLQ + EQ++ + + AEL +EL D+R L+++ EE + S+K+EV
Sbjct: 534 ESLQQQQQEQEEALKQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEV 593
Query: 542 KSADTAATLNLQIAGLQTSVKRLCGEIVELKQ--HLE--HYDKIQELTQMLQESHSSLVS 597
K + G + K+ + +LK+ HLE DK+QE Q + + S
Sbjct: 594 KDT---------VDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSG 644
Query: 598 TNEHLLQEL-SQVRAQHRAEVEQMHWSYQEL--KKTMALFPHSSAS 640
E +L E+ S R Q +SY+E+ +K + P S S
Sbjct: 645 LEELVLSEMNSPSRTQTGDSSSISSFSYREILREKESSAVPARSLS 690
Score = 35.0 bits (79), Expect = 0.22
Identities = 45/172 (26%), Positives = 71/172 (41%), Gaps = 32/172 (18%)
Query: 467 SAMVGEDVGSLALESKSLQSRLA-----------------EQQQQHAREMSEVTAELHHT 509
SA E V L E+ +L++ LA EQ A E+ + AE
Sbjct: 321 SADAQEQVEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDL 380
Query: 510 HKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIV 569
+ DDL L +SL NSR LL +E+ T LQ A + S ++ +
Sbjct: 381 MGQKDDLNSQLQESLRANSR----LLEQLQEIGQEKEQLTQELQEA--RKSAEKRKAMLD 434
Query: 570 ELKQHLEHYDKIQELTQMLQESHSSLVSTNEHLLQELSQVRAQHRAEVEQMH 621
EL + +QE +Q +E L + +E+ VRA++ E+ ++H
Sbjct: 435 ELAM-----ETLQEKSQHKEE----LGAVRLRHEKEVLGVRARYERELRELH 477
>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
sapiens]
Length = 360
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/114 (34%), Positives = 58/114 (50%), Gaps = 5/114 (4%)
Query: 26 DLAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYY 85
+L ELQSL Y +I + +L +LT L+ LD+S N L ++EG+ LT L+ L L
Sbjct: 115 NLEELQSLRELDLYDNQIKKI-ENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVN 173
Query: 86 NCISSLAEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHL----LPKLQQLD 135
N IS + + LH L L R+ + ++ L + L + KLQ LD
Sbjct: 174 NKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLD 227
Score = 43.1 bits (100), Expect = 8e-04
Identities = 27/85 (31%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 56 LKSLDLSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPVVK 115
L LD++ N + +E I +LT L+ + N + S +++ L L V NP+ K
Sbjct: 276 LTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQK 335
Query: 116 VEPDYRLFVVHLLPKLQQLDDRPVR 140
+P YR V+ LP ++Q+D VR
Sbjct: 336 -DPQYRRKVMLALPSVRQIDATFVR 359
Score = 37.0 bits (84), Expect = 0.057
Identities = 26/69 (37%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 49 SLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDF 108
+L +L L+ L+L N + ++E I LT LESL L N I+ L L ALT L +
Sbjct: 181 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQN---LDALTNLTVLSM 237
Query: 109 RLNPVVKVE 117
+ N + K+E
Sbjct: 238 QSNRLTKIE 246
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 25/130 (19%)
Query: 50 LMSLTGLKSLDLSRNSLVSLEGIQY------------------------LTALESLNLYY 85
L L L+ L+LS N + +EGI+ L +L LNL
Sbjct: 143 LDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKG 202
Query: 86 NCISSLAEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRASERK 145
N ISSL ++ +L L +L+ + NPVV + P Y F + L L+ L+ +PV +R+
Sbjct: 203 NKISSLQDISKLKPLQDLISLILVENPVVTL-PHYLQFTIFHLRSLESLEGQPVTTQDRQ 261
Query: 146 ASRLHFASED 155
+ F+ E+
Sbjct: 262 EAFERFSLEE 271
Score = 42.7 bits (99), Expect = 0.001
Identities = 58/239 (24%), Positives = 108/239 (45%), Gaps = 31/239 (12%)
Query: 381 LSQPE--ASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALLETLLDLVDRS-WGGC 437
L +PE A+ +E R + T E + S S + GK A L + +++ RS W
Sbjct: 803 LVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLA---DLQKQFSEILARSKW--- 856
Query: 438 RSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAR 497
E AQ R ++E A Q G++ A E ++L++R+ ++QH
Sbjct: 857 ------ERDEAQVRE--RKLQEEMALQQEKLATGQEEFRQACE-RALEARMNFDKRQHEA 907
Query: 498 EMSEVTAELHHTH---KELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTAATLNLQI 554
+ ++ E+H+ K +++++ D L+E K +L+ +E++ L+
Sbjct: 908 RIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKK-----KLED 962
Query: 555 AGLQTSVKRLCGEIVELKQHLEHYDKI--QELT---QMLQESHSSLVSTNEHLLQELSQ 608
A Q V L E+ +LK+ + DK+ ELT L+ H +++ N+ +EL +
Sbjct: 963 AKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQE 1021
Score = 36.6 bits (83), Expect = 0.074
Identities = 47/210 (22%), Positives = 92/210 (43%), Gaps = 21/210 (10%)
Query: 440 LHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREM 499
+ N+ L Q + +++ +++S + +L + L+ L +Q+ + + +
Sbjct: 1936 IEENKLKLVQQEMMFQRLQKERESEESKLETSKV--TLKEQQHQLEKELTDQKSKLDQVL 1993
Query: 500 SEVTA--ELHHTHKELDDLRQHLDKSLEENSRLKSL-----------LLSMKKEVKSADT 546
S+V A E T +E + + L+K+L + R S LL+++KE S
Sbjct: 1994 SKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSM-- 2051
Query: 547 AATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLV----STNEHL 602
A +L T K+ ++ LK+ L+ E + Q+ +S + +T E +
Sbjct: 2052 RADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELV 2111
Query: 603 LQELSQVRAQHRAEVEQMHWSYQELKKTMA 632
Q+ + + E+ QM + Y ELKK MA
Sbjct: 2112 AQDNHERARRLMKELNQMQYEYTELKKQMA 2141
Score = 30.4 bits (67), Expect = 5.3
Identities = 38/169 (22%), Positives = 70/169 (41%), Gaps = 21/169 (12%)
Query: 477 LALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLS 536
L LE+ LQ L Q Q E+ + + EL++L+Q + E K LL
Sbjct: 1705 LQLENHELQG-LKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLER 1763
Query: 537 MKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDK-----------IQELT 585
K+E++ + + LQ+ V+ L E +L++ + ++K +E +
Sbjct: 1764 DKREIE------RMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS 1817
Query: 586 QMLQESHSSLVSTNEHLLQELSQVRAQHRA---EVEQMHWSYQELKKTM 631
+M Q + L L QEL Q+ + ++ M QE ++ +
Sbjct: 1818 KMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAV 1866
>gi|239754500 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 47.4 bits (111), Expect = 4e-05
Identities = 35/125 (28%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query: 26 DLAELQSLSIPGTYQEKITHLGHSLMSLTG---LKSLDLSRNSLVSLEGIQYLTALESLN 82
DL+ + L + K+ H + LT L L L+ N++ +EG+ YL +L L
Sbjct: 111 DLSRFKKLKYLWLHHNKL----HGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILL 166
Query: 83 LYYNCISSL-AEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRA 141
L++N ++++ A V L + L + NP+ + YRL++++ LP ++ LD V
Sbjct: 167 LHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNL-YRLYIIYHLPGVELLDRNQVTE 225
Query: 142 SERKA 146
ER++
Sbjct: 226 KERRS 230
>gi|239749060 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 47.4 bits (111), Expect = 4e-05
Identities = 35/125 (28%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query: 26 DLAELQSLSIPGTYQEKITHLGHSLMSLTG---LKSLDLSRNSLVSLEGIQYLTALESLN 82
DL+ + L + K+ H + LT L L L+ N++ +EG+ YL +L L
Sbjct: 111 DLSRFKKLKYLWLHHNKL----HGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILL 166
Query: 83 LYYNCISSL-AEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRA 141
L++N ++++ A V L + L + NP+ + YRL++++ LP ++ LD V
Sbjct: 167 LHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNL-YRLYIIYHLPGVELLDRNQVTE 225
Query: 142 SERKA 146
ER++
Sbjct: 226 KERRS 230
>gi|239743086 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 47.4 bits (111), Expect = 4e-05
Identities = 35/125 (28%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query: 26 DLAELQSLSIPGTYQEKITHLGHSLMSLTG---LKSLDLSRNSLVSLEGIQYLTALESLN 82
DL+ + L + K+ H + LT L L L+ N++ +EG+ YL +L L
Sbjct: 111 DLSRFKKLKYLWLHHNKL----HGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILL 166
Query: 83 LYYNCISSL-AEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRA 141
L++N ++++ A V L + L + NP+ + YRL++++ LP ++ LD V
Sbjct: 167 LHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNL-YRLYIIYHLPGVELLDRNQVTE 225
Query: 142 SERKA 146
ER++
Sbjct: 226 KERRS 230
>gi|239508737 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 47.4 bits (111), Expect = 4e-05
Identities = 35/125 (28%), Positives = 64/125 (51%), Gaps = 9/125 (7%)
Query: 26 DLAELQSLSIPGTYQEKITHLGHSLMSLTG---LKSLDLSRNSLVSLEGIQYLTALESLN 82
DL+ + L + K+ H + LT L L L+ N++ +EG+ YL +L L
Sbjct: 111 DLSRFKKLKYLWLHHNKL----HGITFLTRNYCLTELYLNNNAIFEIEGLHYLPSLHILL 166
Query: 83 LYYNCISSL-AEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRA 141
L++N ++++ A V L + L + NP+ + YRL++++ LP ++ LD V
Sbjct: 167 LHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNL-YRLYIIYHLPGVELLDRNQVTE 225
Query: 142 SERKA 146
ER++
Sbjct: 226 KERRS 230
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 47.4 bits (111), Expect = 4e-05
Identities = 121/517 (23%), Positives = 194/517 (37%), Gaps = 82/517 (15%)
Query: 129 PKLQQLDDRPVRASERKASRLHFASEDSLDSKESVPASLKEGRPHHPRAKCTEALAKQSL 188
PK P +ASE++A ED++D+ E S +E P+ K + AL + S
Sbjct: 330 PKADPTGSEPAKASEKEAP------EDTVDAGEE--GSRREEAAKEPKKKAS-ALEEGS- 379
Query: 189 VMDADDEAVLNLIAECEWDLGRPPGSTSFSQKGREADSRGSQESRHLLSPQLVQYQCGDS 248
DA E ++ + E L S S G + R S+ S HLL ++ G +
Sbjct: 380 -SDASQELEISEHMK-EPQLSDSIASDPKSFHGLDFGFR-SRISEHLLDVDVLSPVLGGA 436
Query: 249 GKQGRETRR------SSCRGCCLEKMPWSQLCGELPPLYGAEPEASRAPRPHTYFTPHPD 302
+Q ++ S L+ L L P E A PR P
Sbjct: 437 CRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQ 496
Query: 303 SMDT-----------EDSASSQKLDLSGEMVPGPLPAPGKCRKRRMPVGRFQTFSDQEGL 351
+ EDSA+S L LS + P P P C K + + S E L
Sbjct: 497 GPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSP-PAACEKGK------EQHSQAEEL 549
Query: 352 GCPERTHGSSVPKESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSAL 411
G Q+ +E + P + E RS P S +AL
Sbjct: 550 G---------------PGQEEAEDPEEKVAVSPTPPVSPEVRS--TEPVAPPEQLSEAAL 592
Query: 412 PGKKTALQAALLETLLDLVDRSWGGCRSLHSN------EAFLA---QARHILSSVEEFT- 461
+ A+ L + L++ + L E L Q LSS+ E
Sbjct: 593 KAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERLQ 652
Query: 462 -AAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAE----LHHTHKELDDL 516
A ++ A + E+ ES+ L A+ Q + ++ AE L +EL+
Sbjct: 653 KAIEEEEARMREE------ESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQ 706
Query: 517 RQHLDKSLEENSRLKSLLLSMKKEVKSADTAATLNLQIA---GLQTSVKRLCGEIVELKQ 573
++ SLE+ +R +L +K+E+++++ + L A LQ ++L GE E
Sbjct: 707 QKAERASLEQKNR--QMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVA 764
Query: 574 HLE--HYDKIQELTQMLQESHSSLVSTNEHLLQELSQ 608
LE H +++ L L+ H +VS+ + +QE Q
Sbjct: 765 TLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQ 801
Score = 40.8 bits (94), Expect = 0.004
Identities = 36/153 (23%), Positives = 77/153 (50%), Gaps = 16/153 (10%)
Query: 484 LQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKS 543
L L Q+ H RE+ V E HK L+DLR+ + E+ +L+ L L + E ++
Sbjct: 884 LTGELERLQRAHERELETVRQE---QHKRLEDLRR---RHREQERKLQDLELDL--ETRA 935
Query: 544 ADTAATLNLQIAGLQTSVKRLCGEIVELKQHL----EHYDKIQELTQMLQESHSSLVSTN 599
D A L L + + + +R +++++++ + E + + Q+ H+ L+ +N
Sbjct: 936 KDVKARLAL-LEVQEETARREKQQLLDVQRQVALKSEEATATHQQLEEAQKEHTHLLQSN 994
Query: 600 EHLLQELSQVRAQH---RAEVEQMHWSYQELKK 629
+ L + L +++A+ ++V+ + Q+L+K
Sbjct: 995 QQLREILDELQARKLKLESQVDLLQAQSQQLQK 1027
Score = 31.2 bits (69), Expect = 3.1
Identities = 43/184 (23%), Positives = 73/184 (39%), Gaps = 35/184 (19%)
Query: 364 KESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALL 423
K+ L R+ + E N +P+ + ++S G T+E S S+L K L L
Sbjct: 1039 KQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVS----SSLSQSKEDLY---L 1091
Query: 424 ETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKS 483
++L S H+ L+ L S +EF Q S + +
Sbjct: 1092 DSL------------SSHNVWHLLSAEGVALRSAKEFLVQQTRS-----------MRRRQ 1128
Query: 484 LQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLL-----LSMK 538
+ A+Q +H ++ A+ K L+D+R++L+K +KS + L K
Sbjct: 1129 TALKAAQQHWRHELASAQEVAKDPPGIKALEDMRKNLEKETRHLDEMKSAMRKGHNLLKK 1188
Query: 539 KEVK 542
KE K
Sbjct: 1189 KEEK 1192
Score = 30.0 bits (66), Expect = 6.9
Identities = 57/305 (18%), Positives = 112/305 (36%), Gaps = 22/305 (7%)
Query: 332 CRKRRMPVGRFQTFSDQEGLGCPERTHGSSVPKESLSRQDSSESRNGRTLSQPEASETEE 391
C++ + R +Q ER + +E+ R++ S+ + +++ +E
Sbjct: 626 CQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADE 685
Query: 392 QRSRGVTDT-----REPSPGSHSALPGKKTALQAALLETLLDLVDRSWGGCRSL--HSNE 444
+ R + RE A +LE L + ++ S ++ + E
Sbjct: 686 DQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKE 745
Query: 445 AFLAQARHILSSVEEFTAA---QDSSAMVGEDVGSLALESK----SLQSRLAEQQQQHAR 497
L Q R L + A ++ SA + SL + + SLQ ++ E QQ+
Sbjct: 746 KALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEA 805
Query: 498 EMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTAATLNLQIAGL 557
++ + ++ H + Q L SLL ++EV+ ++
Sbjct: 806 QLQKCLGQVEHR------VHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQ 859
Query: 558 QTSVK-RLCGEIVELKQHLEHYDKIQELTQMLQESHS-SLVSTNEHLLQELSQVRAQHRA 615
Q K R E E KQ E + + LQ +H L + + + L +R +HR
Sbjct: 860 QVMAKAREQYEAEERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHRE 919
Query: 616 EVEQM 620
+ ++
Sbjct: 920 QERKL 924
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 47.4 bits (111), Expect = 4e-05
Identities = 68/289 (23%), Positives = 113/289 (39%), Gaps = 71/289 (24%)
Query: 364 KESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALL 423
K + S Q ++E+ R L EQ VT+ + S L K TA Q
Sbjct: 615 KRNNSLQTATENTQARVLHA-------EQEKAKVTEELAAATAQVSHLQLKMTAHQKKET 667
Query: 424 ETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSS---------------- 467
E + L + SL + Q + + + E + +
Sbjct: 668 ELQMQLTE-------SLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLEL 720
Query: 468 --AMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHTHK----ELDDLRQHLD 521
+ E++ L +E +SL+ L+E++++ A+E S+ E+ K ELD LRQ L
Sbjct: 721 KVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLL- 779
Query: 522 KSLEENSRLKSLLLSMKKEVKSADTAAT--LNLQIAGLQTSVKRLCGEIV--ELKQHLEH 577
KK S D AA L+L A LQT + C ++ +HL+
Sbjct: 780 ----------------KKTRVSTDQAAAEQLSLVQAELQTQWEAKCEHLLASAKDEHLQQ 823
Query: 578 YDKI--------QELTQM------LQESHSSLVSTNEHLLQELSQVRAQ 612
Y ++ Q+L Q+ LQ ++L NE ++EL + ++Q
Sbjct: 824 YQEVCAQRDAYQQKLVQLQEKCLALQAQITALTKQNEQHIKELEKNKSQ 872
Score = 40.0 bits (92), Expect = 0.007
Identities = 38/174 (21%), Positives = 85/174 (48%), Gaps = 21/174 (12%)
Query: 464 QDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAR---EMSEVTAELHHTH-------KEL 513
+ S+ M+ + SL +++ Q+R+ +Q+ A+ E++ TA++ H K+
Sbjct: 607 EQSNLMMEKRNNSLQTATENTQARVLHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKE 666
Query: 514 DDLRQHLDKSLEENSRLKSLLLSMKKEVKSA-DTAATLNLQIAGLQTSVKRLCGEIVELK 572
+L+ L +SL+E L+ L ++ ++ +T+ + + + K+L ++ L+
Sbjct: 667 TELQMQLTESLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLE 726
Query: 573 QHLEHYDKIQELTQMLQESHSSLVSTNEHLLQELSQVRAQHRAEVEQMHWSYQE 626
+ ELT + E S + +E ++ +Q R+Q E++++ SYQE
Sbjct: 727 E---------ELTDLRVEKESLEKNLSERK-KKSAQERSQAEEEIDEIRKSYQE 770
Score = 36.6 bits (83), Expect = 0.074
Identities = 41/177 (23%), Positives = 78/177 (44%), Gaps = 25/177 (14%)
Query: 463 AQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDK 522
A+ A V E++ + + LQ ++ H ++ +E+ +L + KE D LR L K
Sbjct: 634 AEQEKAKVTEELAAATAQVSHLQLKMTA----HQKKETELQMQLTESLKETDLLRGQLTK 689
Query: 523 SLEENSRLKSLLLSMKKEVKSA-DTAATLNLQIAGLQTSVKRLCGEIVELKQHL------ 575
+ S L+ + + KS L L++ L+ + L E L+++L
Sbjct: 690 VQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERKKK 749
Query: 576 ---------EHYDKI-----QELTQMLQESHSSLVSTNEHLLQELSQVRAQHRAEVE 618
E D+I +EL ++ Q + VST++ ++LS V+A+ + + E
Sbjct: 750 SAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQAAAEQLSLVQAELQTQWE 806
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 47.0 bits (110), Expect = 5e-05
Identities = 57/259 (22%), Positives = 102/259 (39%), Gaps = 29/259 (11%)
Query: 365 ESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALLE 424
E R ++ +N +TL + A E R G + + KK L+A + E
Sbjct: 1213 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQ---------AKQEVEHKKKKLEAQVQE 1263
Query: 425 TLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSL 484
D G N+ + S A+ + + +DV SL+ + +
Sbjct: 1264 LQSKCSD---GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
Query: 485 QSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEV--- 541
Q L Q+ R+ V+ +L +E + L+ LD+ +E L+ + ++ ++
Sbjct: 1321 QELL----QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS 1376
Query: 542 --KSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEH----YDKIQELTQMLQESHSSL 595
K D A+T + L+ KR EI L Q E YDK+++ LQ+ L
Sbjct: 1377 KKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Query: 596 VSTNEHLLQELSQVRAQHR 614
V ++ Q +S + + R
Sbjct: 1433 VVDLDNQRQLVSNLEKKQR 1451
Score = 38.5 bits (88), Expect = 0.019
Identities = 65/266 (24%), Positives = 111/266 (41%), Gaps = 27/266 (10%)
Query: 364 KESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALL 423
KE SRQ+ + + R L + +AS+ EQ + D + L K+ LQAAL
Sbjct: 1045 KEEKSRQELEKLK--RKL-EGDASDFHEQ----IADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 424 ETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEF-TAAQDSSAMVGEDVGSLALESK 482
L D + + + + E ++ + L S A+ +GE++ +L E +
Sbjct: 1098 R-LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Query: 483 SLQSRLAEQQQQHAREMSEVTA-------ELHHTHKELDDLRQHLDKSLEE-NSRLKSLL 534
A QQ+ A+ EVT E ++ ++RQ +++EE +L+
Sbjct: 1157 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1216
Query: 535 LSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSS 594
+ K+ T N +AG R+ G + KQ +EH K ++L +QE S
Sbjct: 1217 RAKANLDKNKQTLEKENADLAG----ELRVLG---QAKQEVEH--KKKKLEAQVQELQSK 1267
Query: 595 LVSTNEHLLQELSQVRAQHRAEVEQM 620
S E EL+ + + EVE +
Sbjct: 1268 -CSDGERARAELNDKVHKLQNEVESV 1292
Score = 35.4 bits (80), Expect = 0.16
Identities = 39/208 (18%), Positives = 93/208 (44%), Gaps = 26/208 (12%)
Query: 444 EAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVT 503
E A+ + + E A++ + + L E LQ +L + + +A E E+
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMR 910
Query: 504 AELHHTHKELDDLRQHLDKSLE-----------ENSRLKSLLLSMKKEVKSADTA-ATLN 551
L +EL+++ ++ LE E ++ +L ++++++ + A L
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 552 LQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSL---VSTNEHLLQELSQ 608
L+ + +K+L EI+ + + +K+ + ++L+E S L ++ E + L++
Sbjct: 971 LEKVTAEAKIKKLEDEILVMD---DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Query: 609 VRAQHRAEVEQM-------HWSYQELKK 629
++ +H + + ++ S QEL+K
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEK 1055
Score = 34.3 bits (77), Expect = 0.37
Identities = 31/137 (22%), Positives = 68/137 (49%), Gaps = 10/137 (7%)
Query: 480 ESKSLQSRLAEQQQQHAREMSEVTAELHHTHK---ELDDLRQHLDKSLEENSRLKSLLLS 536
E++S ++++ E +Q+HA+ + E+T +L + LD +Q L+K + + +L
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245
Query: 537 MKKEVKSADTAATLNLQIAGLQTSV---KRLCGEIVELKQHLEHYDKIQELTQMLQESHS 593
K+EV+ L Q+ LQ+ +R E+ + L+ ++++ +T ML E+
Sbjct: 1246 AKQEVE--HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ--NEVESVTGMLNEAEG 1301
Query: 594 SLVSTNEHLLQELSQVR 610
+ + + SQ++
Sbjct: 1302 KAIKLAKDVASLSSQLQ 1318
Score = 32.3 bits (72), Expect = 1.4
Identities = 58/270 (21%), Positives = 107/270 (39%), Gaps = 38/270 (14%)
Query: 386 ASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAA---------LLETLLDLVDRSWGG 436
+S+ ++R R + RE + S + AL+A L + DLV
Sbjct: 1464 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1523
Query: 437 CRSLH----SNEAFLAQARHILSSVEEFT----AAQDSSAMVGEDVGSLALESKSLQSRL 488
+++H S A Q + + +EE A +D+ + +V AL+ + + L
Sbjct: 1524 GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL--EVNMQALKGQ-FERDL 1580
Query: 489 AEQQQQHAREMSEVTAELHHTHKELDDLRQH------LDKSLEENSRLKSLLLSMKKEVK 542
+ +Q+ + ++ +LH EL+D R+ K LE + LK L L +K
Sbjct: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD--LKDLELQADSAIK 1638
Query: 543 SADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHL 602
+ A Q+ LQ +K E+ + + + E+ +E+ S L
Sbjct: 1639 GREEAIK---QLRKLQAQMKDFQRELEDARASRD------EIFATAKENEKKAKSLEADL 1689
Query: 603 LQELSQVRAQHRAEVEQMHWSYQELKKTMA 632
+Q + A RA +Q +EL + +A
Sbjct: 1690 MQLQEDLAAAERAR-KQADLEKEELAEELA 1718
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 47.0 bits (110), Expect = 5e-05
Identities = 57/259 (22%), Positives = 102/259 (39%), Gaps = 29/259 (11%)
Query: 365 ESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALLE 424
E R ++ +N +TL + A E R G + + KK L+A + E
Sbjct: 1220 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQ---------AKQEVEHKKKKLEAQVQE 1270
Query: 425 TLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSL 484
D G N+ + S A+ + + +DV SL+ + +
Sbjct: 1271 LQSKCSD---GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1327
Query: 485 QSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEV--- 541
Q L Q+ R+ V+ +L +E + L+ LD+ +E L+ + ++ ++
Sbjct: 1328 QELL----QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS 1383
Query: 542 --KSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEH----YDKIQELTQMLQESHSSL 595
K D A+T + L+ KR EI L Q E YDK+++ LQ+ L
Sbjct: 1384 KKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Query: 596 VSTNEHLLQELSQVRAQHR 614
V ++ Q +S + + R
Sbjct: 1440 VVDLDNQRQLVSNLEKKQR 1458
Score = 38.5 bits (88), Expect = 0.019
Identities = 65/266 (24%), Positives = 111/266 (41%), Gaps = 27/266 (10%)
Query: 364 KESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALL 423
KE SRQ+ + + R L + +AS+ EQ + D + L K+ LQAAL
Sbjct: 1052 KEEKSRQELEKLK--RKL-EGDASDFHEQ----IADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 424 ETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEF-TAAQDSSAMVGEDVGSLALESK 482
L D + + + + E ++ + L S A+ +GE++ +L E +
Sbjct: 1105 R-LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Query: 483 SLQSRLAEQQQQHAREMSEVTA-------ELHHTHKELDDLRQHLDKSLEE-NSRLKSLL 534
A QQ+ A+ EVT E ++ ++RQ +++EE +L+
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223
Query: 535 LSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSS 594
+ K+ T N +AG R+ G + KQ +EH K ++L +QE S
Sbjct: 1224 RAKANLDKNKQTLEKENADLAG----ELRVLG---QAKQEVEH--KKKKLEAQVQELQSK 1274
Query: 595 LVSTNEHLLQELSQVRAQHRAEVEQM 620
S E EL+ + + EVE +
Sbjct: 1275 -CSDGERARAELNDKVHKLQNEVESV 1299
Score = 35.4 bits (80), Expect = 0.16
Identities = 39/208 (18%), Positives = 93/208 (44%), Gaps = 26/208 (12%)
Query: 444 EAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVT 503
E A+ + + E A++ + + L E LQ +L + + +A E E+
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMR 917
Query: 504 AELHHTHKELDDLRQHLDKSLE-----------ENSRLKSLLLSMKKEVKSADTA-ATLN 551
L +EL+++ ++ LE E ++ +L ++++++ + A L
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 552 LQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSL---VSTNEHLLQELSQ 608
L+ + +K+L EI+ + + +K+ + ++L+E S L ++ E + L++
Sbjct: 978 LEKVTAEAKIKKLEDEILVMD---DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Query: 609 VRAQHRAEVEQM-------HWSYQELKK 629
++ +H + + ++ S QEL+K
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEK 1062
Score = 34.3 bits (77), Expect = 0.37
Identities = 31/137 (22%), Positives = 68/137 (49%), Gaps = 10/137 (7%)
Query: 480 ESKSLQSRLAEQQQQHAREMSEVTAELHHTHK---ELDDLRQHLDKSLEENSRLKSLLLS 536
E++S ++++ E +Q+HA+ + E+T +L + LD +Q L+K + + +L
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252
Query: 537 MKKEVKSADTAATLNLQIAGLQTSV---KRLCGEIVELKQHLEHYDKIQELTQMLQESHS 593
K+EV+ L Q+ LQ+ +R E+ + L+ ++++ +T ML E+
Sbjct: 1253 AKQEVE--HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ--NEVESVTGMLNEAEG 1308
Query: 594 SLVSTNEHLLQELSQVR 610
+ + + SQ++
Sbjct: 1309 KAIKLAKDVASLSSQLQ 1325
Score = 32.3 bits (72), Expect = 1.4
Identities = 58/270 (21%), Positives = 107/270 (39%), Gaps = 38/270 (14%)
Query: 386 ASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAA---------LLETLLDLVDRSWGG 436
+S+ ++R R + RE + S + AL+A L + DLV
Sbjct: 1471 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1530
Query: 437 CRSLH----SNEAFLAQARHILSSVEEFT----AAQDSSAMVGEDVGSLALESKSLQSRL 488
+++H S A Q + + +EE A +D+ + +V AL+ + + L
Sbjct: 1531 GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL--EVNMQALKGQ-FERDL 1587
Query: 489 AEQQQQHAREMSEVTAELHHTHKELDDLRQH------LDKSLEENSRLKSLLLSMKKEVK 542
+ +Q+ + ++ +LH EL+D R+ K LE + LK L L +K
Sbjct: 1588 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD--LKDLELQADSAIK 1645
Query: 543 SADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHL 602
+ A Q+ LQ +K E+ + + + E+ +E+ S L
Sbjct: 1646 GREEAIK---QLRKLQAQMKDFQRELEDARASRD------EIFATAKENEKKAKSLEADL 1696
Query: 603 LQELSQVRAQHRAEVEQMHWSYQELKKTMA 632
+Q + A RA +Q +EL + +A
Sbjct: 1697 MQLQEDLAAAERAR-KQADLEKEELAEELA 1725
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 47.0 bits (110), Expect = 5e-05
Identities = 57/259 (22%), Positives = 102/259 (39%), Gaps = 29/259 (11%)
Query: 365 ESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALLE 424
E R ++ +N +TL + A E R G + + KK L+A + E
Sbjct: 1220 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQ---------AKQEVEHKKKKLEAQVQE 1270
Query: 425 TLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSL 484
D G N+ + S A+ + + +DV SL+ + +
Sbjct: 1271 LQSKCSD---GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1327
Query: 485 QSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEV--- 541
Q L Q+ R+ V+ +L +E + L+ LD+ +E L+ + ++ ++
Sbjct: 1328 QELL----QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS 1383
Query: 542 --KSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEH----YDKIQELTQMLQESHSSL 595
K D A+T + L+ KR EI L Q E YDK+++ LQ+ L
Sbjct: 1384 KKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1439
Query: 596 VSTNEHLLQELSQVRAQHR 614
V ++ Q +S + + R
Sbjct: 1440 VVDLDNQRQLVSNLEKKQR 1458
Score = 38.5 bits (88), Expect = 0.019
Identities = 65/266 (24%), Positives = 111/266 (41%), Gaps = 27/266 (10%)
Query: 364 KESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALL 423
KE SRQ+ + + R L + +AS+ EQ + D + L K+ LQAAL
Sbjct: 1052 KEEKSRQELEKLK--RKL-EGDASDFHEQ----IADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 424 ETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEF-TAAQDSSAMVGEDVGSLALESK 482
L D + + + + E ++ + L S A+ +GE++ +L E +
Sbjct: 1105 R-LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Query: 483 SLQSRLAEQQQQHAREMSEVTA-------ELHHTHKELDDLRQHLDKSLEE-NSRLKSLL 534
A QQ+ A+ EVT E ++ ++RQ +++EE +L+
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1223
Query: 535 LSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSS 594
+ K+ T N +AG R+ G + KQ +EH K ++L +QE S
Sbjct: 1224 RAKANLDKNKQTLEKENADLAG----ELRVLG---QAKQEVEH--KKKKLEAQVQELQSK 1274
Query: 595 LVSTNEHLLQELSQVRAQHRAEVEQM 620
S E EL+ + + EVE +
Sbjct: 1275 -CSDGERARAELNDKVHKLQNEVESV 1299
Score = 35.4 bits (80), Expect = 0.16
Identities = 39/208 (18%), Positives = 93/208 (44%), Gaps = 26/208 (12%)
Query: 444 EAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVT 503
E A+ + + E A++ + + L E LQ +L + + +A E E+
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMR 917
Query: 504 AELHHTHKELDDLRQHLDKSLE-----------ENSRLKSLLLSMKKEVKSADTA-ATLN 551
L +EL+++ ++ LE E ++ +L ++++++ + A L
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 977
Query: 552 LQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSL---VSTNEHLLQELSQ 608
L+ + +K+L EI+ + + +K+ + ++L+E S L ++ E + L++
Sbjct: 978 LEKVTAEAKIKKLEDEILVMD---DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1034
Query: 609 VRAQHRAEVEQM-------HWSYQELKK 629
++ +H + + ++ S QEL+K
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEK 1062
Score = 34.3 bits (77), Expect = 0.37
Identities = 31/137 (22%), Positives = 68/137 (49%), Gaps = 10/137 (7%)
Query: 480 ESKSLQSRLAEQQQQHAREMSEVTAELHHTHK---ELDDLRQHLDKSLEENSRLKSLLLS 536
E++S ++++ E +Q+HA+ + E+T +L + LD +Q L+K + + +L
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252
Query: 537 MKKEVKSADTAATLNLQIAGLQTSV---KRLCGEIVELKQHLEHYDKIQELTQMLQESHS 593
K+EV+ L Q+ LQ+ +R E+ + L+ ++++ +T ML E+
Sbjct: 1253 AKQEVE--HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ--NEVESVTGMLNEAEG 1308
Query: 594 SLVSTNEHLLQELSQVR 610
+ + + SQ++
Sbjct: 1309 KAIKLAKDVASLSSQLQ 1325
Score = 32.3 bits (72), Expect = 1.4
Identities = 58/270 (21%), Positives = 107/270 (39%), Gaps = 38/270 (14%)
Query: 386 ASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAA---------LLETLLDLVDRSWGG 436
+S+ ++R R + RE + S + AL+A L + DLV
Sbjct: 1471 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1530
Query: 437 CRSLH----SNEAFLAQARHILSSVEEFT----AAQDSSAMVGEDVGSLALESKSLQSRL 488
+++H S A Q + + +EE A +D+ + +V AL+ + + L
Sbjct: 1531 GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL--EVNMQALKGQ-FERDL 1587
Query: 489 AEQQQQHAREMSEVTAELHHTHKELDDLRQH------LDKSLEENSRLKSLLLSMKKEVK 542
+ +Q+ + ++ +LH EL+D R+ K LE + LK L L +K
Sbjct: 1588 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD--LKDLELQADSAIK 1645
Query: 543 SADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHL 602
+ A Q+ LQ +K E+ + + + E+ +E+ S L
Sbjct: 1646 GREEAIK---QLRKLQAQMKDFQRELEDARASRD------EIFATAKENEKKAKSLEADL 1696
Query: 603 LQELSQVRAQHRAEVEQMHWSYQELKKTMA 632
+Q + A RA +Q +EL + +A
Sbjct: 1697 MQLQEDLAAAERAR-KQADLEKEELAEELA 1725
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 47.0 bits (110), Expect = 5e-05
Identities = 57/259 (22%), Positives = 102/259 (39%), Gaps = 29/259 (11%)
Query: 365 ESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALLE 424
E R ++ +N +TL + A E R G + + KK L+A + E
Sbjct: 1213 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQ---------AKQEVEHKKKKLEAQVQE 1263
Query: 425 TLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSL 484
D G N+ + S A+ + + +DV SL+ + +
Sbjct: 1264 LQSKCSD---GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
Query: 485 QSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEV--- 541
Q L Q+ R+ V+ +L +E + L+ LD+ +E L+ + ++ ++
Sbjct: 1321 QELL----QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDS 1376
Query: 542 --KSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEH----YDKIQELTQMLQESHSSL 595
K D A+T + L+ KR EI L Q E YDK+++ LQ+ L
Sbjct: 1377 KKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDL 1432
Query: 596 VSTNEHLLQELSQVRAQHR 614
V ++ Q +S + + R
Sbjct: 1433 VVDLDNQRQLVSNLEKKQR 1451
Score = 38.5 bits (88), Expect = 0.019
Identities = 65/266 (24%), Positives = 111/266 (41%), Gaps = 27/266 (10%)
Query: 364 KESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALL 423
KE SRQ+ + + R L + +AS+ EQ + D + L K+ LQAAL
Sbjct: 1045 KEEKSRQELEKLK--RKL-EGDASDFHEQ----IADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 424 ETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEF-TAAQDSSAMVGEDVGSLALESK 482
L D + + + + E ++ + L S A+ +GE++ +L E +
Sbjct: 1098 R-LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Query: 483 SLQSRLAEQQQQHAREMSEVTA-------ELHHTHKELDDLRQHLDKSLEE-NSRLKSLL 534
A QQ+ A+ EVT E ++ ++RQ +++EE +L+
Sbjct: 1157 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 1216
Query: 535 LSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSS 594
+ K+ T N +AG R+ G + KQ +EH K ++L +QE S
Sbjct: 1217 RAKANLDKNKQTLEKENADLAG----ELRVLG---QAKQEVEH--KKKKLEAQVQELQSK 1267
Query: 595 LVSTNEHLLQELSQVRAQHRAEVEQM 620
S E EL+ + + EVE +
Sbjct: 1268 -CSDGERARAELNDKVHKLQNEVESV 1292
Score = 35.4 bits (80), Expect = 0.16
Identities = 39/208 (18%), Positives = 93/208 (44%), Gaps = 26/208 (12%)
Query: 444 EAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVT 503
E A+ + + E A++ + + L E LQ +L + + +A E E+
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMR 910
Query: 504 AELHHTHKELDDLRQHLDKSLE-----------ENSRLKSLLLSMKKEVKSADTA-ATLN 551
L +EL+++ ++ LE E ++ +L ++++++ + A L
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
Query: 552 LQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSL---VSTNEHLLQELSQ 608
L+ + +K+L EI+ + + +K+ + ++L+E S L ++ E + L++
Sbjct: 971 LEKVTAEAKIKKLEDEILVMD---DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTK 1027
Query: 609 VRAQHRAEVEQM-------HWSYQELKK 629
++ +H + + ++ S QEL+K
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEK 1055
Score = 34.3 bits (77), Expect = 0.37
Identities = 31/137 (22%), Positives = 68/137 (49%), Gaps = 10/137 (7%)
Query: 480 ESKSLQSRLAEQQQQHAREMSEVTAELHHTHK---ELDDLRQHLDKSLEENSRLKSLLLS 536
E++S ++++ E +Q+HA+ + E+T +L + LD +Q L+K + + +L
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245
Query: 537 MKKEVKSADTAATLNLQIAGLQTSV---KRLCGEIVELKQHLEHYDKIQELTQMLQESHS 593
K+EV+ L Q+ LQ+ +R E+ + L+ ++++ +T ML E+
Sbjct: 1246 AKQEVE--HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ--NEVESVTGMLNEAEG 1301
Query: 594 SLVSTNEHLLQELSQVR 610
+ + + SQ++
Sbjct: 1302 KAIKLAKDVASLSSQLQ 1318
Score = 32.3 bits (72), Expect = 1.4
Identities = 58/270 (21%), Positives = 107/270 (39%), Gaps = 38/270 (14%)
Query: 386 ASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAA---------LLETLLDLVDRSWGG 436
+S+ ++R R + RE + S + AL+A L + DLV
Sbjct: 1464 SSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1523
Query: 437 CRSLH----SNEAFLAQARHILSSVEEFT----AAQDSSAMVGEDVGSLALESKSLQSRL 488
+++H S A Q + + +EE A +D+ + +V AL+ + + L
Sbjct: 1524 GKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL--EVNMQALKGQ-FERDL 1580
Query: 489 AEQQQQHAREMSEVTAELHHTHKELDDLRQH------LDKSLEENSRLKSLLLSMKKEVK 542
+ +Q+ + ++ +LH EL+D R+ K LE + LK L L +K
Sbjct: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD--LKDLELQADSAIK 1638
Query: 543 SADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHL 602
+ A Q+ LQ +K E+ + + + E+ +E+ S L
Sbjct: 1639 GREEAIK---QLRKLQAQMKDFQRELEDARASRD------EIFATAKENEKKAKSLEADL 1689
Query: 603 LQELSQVRAQHRAEVEQMHWSYQELKKTMA 632
+Q + A RA +Q +EL + +A
Sbjct: 1690 MQLQEDLAAAERAR-KQADLEKEELAEELA 1718
>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 47.0 bits (110), Expect = 5e-05
Identities = 47/157 (29%), Positives = 71/157 (45%), Gaps = 28/157 (17%)
Query: 30 LQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCIS 89
L+ L + EKI L +L L LDLS N++ ++EG+ L LE L+L+ N IS
Sbjct: 67 LRKLQLDNNIIEKI----EGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRIS 122
Query: 90 ---SLAEVFRLHALTE-------------------LVDVDFRLNPVVKVEPDYRLFVVHL 127
SL + +L L+ L + NP+ + E DY++F+
Sbjct: 123 KIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAE-DYKMFICAY 181
Query: 128 LPKLQQLDDRPVRASERK-ASRLHFASEDSLDSKESV 163
LP L LD R + +K A H S D L +E++
Sbjct: 182 LPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENL 218
>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 47.0 bits (110), Expect = 5e-05
Identities = 47/157 (29%), Positives = 71/157 (45%), Gaps = 28/157 (17%)
Query: 30 LQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCIS 89
L+ L + EKI L +L L LDLS N++ ++EG+ L LE L+L+ N IS
Sbjct: 67 LRKLQLDNNIIEKI----EGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRIS 122
Query: 90 ---SLAEVFRLHALTE-------------------LVDVDFRLNPVVKVEPDYRLFVVHL 127
SL + +L L+ L + NP+ + E DY++F+
Sbjct: 123 KIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAE-DYKMFICAY 181
Query: 128 LPKLQQLDDRPVRASERK-ASRLHFASEDSLDSKESV 163
LP L LD R + +K A H S D L +E++
Sbjct: 182 LPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENL 218
>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 47.0 bits (110), Expect = 5e-05
Identities = 47/157 (29%), Positives = 71/157 (45%), Gaps = 28/157 (17%)
Query: 30 LQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCIS 89
L+ L + EKI L +L L LDLS N++ ++EG+ L LE L+L+ N IS
Sbjct: 67 LRKLQLDNNIIEKI----EGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRIS 122
Query: 90 ---SLAEVFRLHALTE-------------------LVDVDFRLNPVVKVEPDYRLFVVHL 127
SL + +L L+ L + NP+ + E DY++F+
Sbjct: 123 KIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAE-DYKMFICAY 181
Query: 128 LPKLQQLDDRPVRASERK-ASRLHFASEDSLDSKESV 163
LP L LD R + +K A H S D L +E++
Sbjct: 182 LPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENL 218
>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 47.0 bits (110), Expect = 5e-05
Identities = 47/157 (29%), Positives = 71/157 (45%), Gaps = 28/157 (17%)
Query: 30 LQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCIS 89
L+ L + EKI L +L L LDLS N++ ++EG+ L LE L+L+ N IS
Sbjct: 67 LRKLQLDNNIIEKI----EGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRIS 122
Query: 90 ---SLAEVFRLHALTE-------------------LVDVDFRLNPVVKVEPDYRLFVVHL 127
SL + +L L+ L + NP+ + E DY++F+
Sbjct: 123 KIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAE-DYKMFICAY 181
Query: 128 LPKLQQLDDRPVRASERK-ASRLHFASEDSLDSKESV 163
LP L LD R + +K A H S D L +E++
Sbjct: 182 LPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENL 218
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 46.6 bits (109), Expect = 7e-05
Identities = 78/341 (22%), Positives = 137/341 (40%), Gaps = 44/341 (12%)
Query: 306 TEDSASSQKLDLSGEMVPGP--LPAPGKCRKRRMPVGRFQTFSDQEGLGCPERTHGSSVP 363
T D+++ LSG+ P P +PG+ R R G SD L S++
Sbjct: 476 TADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRR--GPSPACSDSSTLALIH----SALH 529
Query: 364 KESLSRQD------SSESRNGRTLSQPEASETEEQR-SRGVTDTREPSPGSHSALPGKKT 416
K L QD +S+ G Q SE+E + + R+ + G+ A +
Sbjct: 530 KRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQR 589
Query: 417 ALQAALLETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGS 476
+Q L + +L+ R HS + QA + E+ AAQ+
Sbjct: 590 EVQR--LRSANELLSREKSNLA--HSLQVAQQQAEELRQEREKLQAAQE----------- 634
Query: 477 LALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDL---RQHLDKSLEE--NSRLK 531
E + + RL E+Q+ ++ + V EL +H++L+ L R L K L E + +
Sbjct: 635 ---ELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSR 691
Query: 532 SLLLSMKKEVKSADTAATLNLQIAG---LQTSVKRLCGEIVELKQHLEHYDKIQELTQML 588
+ L + + A+ A L AG L+ S+ +L E L+ L K+ L + L
Sbjct: 692 ATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSL---SKLSALNESL 748
Query: 589 QESHSSLVSTNEHLLQELSQVRAQHRAEVEQMHWSYQELKK 629
+ L L +E S ++ + R ++ + +E ++
Sbjct: 749 AQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQER 789
Score = 38.9 bits (89), Expect = 0.015
Identities = 76/355 (21%), Positives = 133/355 (37%), Gaps = 47/355 (13%)
Query: 309 SASSQKLDLSGEMVPGPLPAPGKCRKRRMPVGRFQTFSDQEGLGCPERTHGSSVPKESLS 368
SA + L L P P P PG + G + + L C + GS P +
Sbjct: 1438 SALRRGLGLGRAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLEC---SPGSQPPSPGPA 1494
Query: 369 RQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALLETLLD 428
+S + + +E RS + L + +AL L E +
Sbjct: 1495 TSPASPDLDPEAVRGALREFLQELRS---------AQRERDELRTQTSALNRQLAEMEAE 1545
Query: 429 LVDRSWGGCRSLHSNEAFLAQARHI----LSSVEEFTAAQDSSAMVGEDVGSLALESKSL 484
D + R L A +AR LS V+ A Q+ S E L+ +
Sbjct: 1546 R-DSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVAT 1604
Query: 485 QSRLAEQQQQHAREMSEVTAELHHTHKELDD----LRQHLDKSLEENSRLKSLLLSMKKE 540
R + + R E +++ +L+ L++ LD S +L+ S++ E
Sbjct: 1605 LERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGE 1664
Query: 541 VKSA---------------DTAATLNLQIAG-------LQTSVKRLCGEIVELKQHLEHY 578
++ + D +L Q+A LQ +V+RL G + ++++
Sbjct: 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGAL 1724
Query: 579 -DKIQELTQMLQESHSSLVST---NEHLLQELSQVRAQHRAEVEQMHWSYQELKK 629
DK++ LT+ L +S +SL ST N HL + L+ + E++ + Q L +
Sbjct: 1725 RDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSE 1779
Score = 30.8 bits (68), Expect = 4.1
Identities = 33/185 (17%), Positives = 78/185 (42%), Gaps = 7/185 (3%)
Query: 458 EEFTAAQDSSAMVGEDVGSLALES-KSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDL 516
++ A Q+ +++ E + +++ + Q+ L EQ+ H ++ + E +EL+
Sbjct: 953 QQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAE 1012
Query: 517 RQHLDKSLEENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLE 576
R L L+ L +KE S + AA + GL + + + LK+
Sbjct: 1013 RAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEK-QQALSLKE--- 1068
Query: 577 HYDKIQELTQMLQESHSSLVSTNEHLLQELSQVRAQHRAEVEQMHWSYQELKKTMALFPH 636
+ L++ L + SL + + + ++ +++ + ++ EL+ A
Sbjct: 1069 --SEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREE 1126
Query: 637 SSASH 641
++A+H
Sbjct: 1127 AAAAH 1131
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 46.2 bits (108), Expect = 9e-05
Identities = 39/139 (28%), Positives = 71/139 (51%), Gaps = 6/139 (4%)
Query: 479 LESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMK 538
L+SK L S+ E + R M+E +++ H LD ++ + L E +S L
Sbjct: 312 LQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQ-KEKENIHLREELHRRSQLQPEP 370
Query: 539 KEVKSADTAATL-NLQIAGLQTSVKRLCGEIVELKQH--LEHYDKIQELTQM-LQESHSS 594
+ K+ T + + +IA L+ +++ L EI LK + L D+ +E+ Q+ + +SHS
Sbjct: 371 AKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSK 430
Query: 595 LVSTN-EHLLQELSQVRAQ 612
+ T + L QELS+ ++
Sbjct: 431 FMKTKIDQLKQELSKKESE 449
Score = 38.9 bits (89), Expect = 0.015
Identities = 40/181 (22%), Positives = 81/181 (44%), Gaps = 30/181 (16%)
Query: 451 RHILSSVEEFTAAQDSSAMVGEDVGSLAL---ESKSLQSRLAEQQQQHAREMSEVTAELH 507
+HI E TA + +A++ +V +L L E +S ++ +Q Q E + E+
Sbjct: 469 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIR 528
Query: 508 HT--------------HKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTA-ATLNL 552
K++++L++ L ++ + LK + S++ + + DTA ATL
Sbjct: 529 DMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEE 588
Query: 553 QIAGLQTSVKRLCGE--------IVEL----KQHLEHYDKIQELTQMLQESHSSLVSTNE 600
++ + ++RL + + E+ K++ + +K+ L L E SSL+ E
Sbjct: 589 ALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKE 648
Query: 601 H 601
H
Sbjct: 649 H 649
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 45.8 bits (107), Expect = 1e-04
Identities = 54/249 (21%), Positives = 114/249 (45%), Gaps = 19/249 (7%)
Query: 364 KESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALL 423
KE LS+ + E+R+ SQ E ++ E + + + D S +K L+ +
Sbjct: 2287 KELLSQLE--ETRHLYHSSQNELAKLESEL-KSLKDQLTDLSNSLEKCKEQKGNLEGIIR 2343
Query: 424 ETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKS 483
+ D+ + + S E L +R + S + E ++ + L+ + ++
Sbjct: 2344 QQEADIQNSKF----SYEQLETDLQASRELTSRLHEEINMKEQKI-----ISLLSGKEEA 2394
Query: 484 LQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKE-VK 542
+Q +AE +QQH +E+ E+ L +E L + K++++ ++L L ++KKE ++
Sbjct: 2395 IQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQ 2454
Query: 543 SADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHL 602
+ ++ LQ R+ G+ +L++ H I E Q++QE+ + N L
Sbjct: 2455 QKAQLDSFVKSMSSLQNDRDRIVGDYQQLEE--RHLSIILEKDQLIQEA----AAENNKL 2508
Query: 603 LQELSQVRA 611
+E+ +R+
Sbjct: 2509 KEEIRGLRS 2517
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 30/184 (16%)
Query: 456 SVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDD 515
+++E + Q+ ++ + L ++S+++ Q +E V L +E D
Sbjct: 1495 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQN----KEKDTVLGRLALLQEERDK 1550
Query: 516 LRQHLDKSLEENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHL 575
L +D+SL EN L S + +L L + GL ++L EI LK
Sbjct: 1551 LITEMDRSLLENQSLSS-------------SCESLKLALEGLTEDKEKLVKEIESLKS-- 1595
Query: 576 EHYDKIQELTQMLQESHSSLVSTNEHLLQELSQV-----RAQHRAEV--EQMHWSYQELK 628
KI E T+ QE H L E LLQ V R QH E ++ Y +L+
Sbjct: 1596 ---SKIAESTEW-QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR 1651
Query: 629 KTMA 632
T A
Sbjct: 1652 STEA 1655
Score = 41.2 bits (95), Expect = 0.003
Identities = 69/301 (22%), Positives = 129/301 (42%), Gaps = 59/301 (19%)
Query: 365 ESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSH-----SALPGKKTALQ 419
E + RQ ++ +N + E ET+ Q SR +T S L GK+ A+Q
Sbjct: 2339 EGIIRQQEADIQNSKF--SYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ 2396
Query: 420 AALLETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLAL 479
A+ E L D+ +L S E + +I+ EE A D + + E + ++
Sbjct: 2397 VAIAE-LRQQHDKEIKELENLLSQE----EEENIVLE-EENKKAVDKTNQLMETLKTIKK 2450
Query: 480 ES-----------KSLQSR-------LAEQQQQHAREMS----------EVTAELHHTHK 511
E+ KS+ S + + QQ R +S E AE + +
Sbjct: 2451 ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2510
Query: 512 ELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVEL 571
E+ LR H+D EN++L + L+ ++++ Q+ ++ S ++ E V+L
Sbjct: 2511 EIRGLRSHMDDLNSENAKLDAELIQYREDLN----------QVITIKDSQQKQLLE-VQL 2559
Query: 572 KQHLEHYDKIQELTQMLQESHSSLVSTNEHLLQELSQVRAQHR---AEVEQMHWSYQELK 628
+Q+ E +K +L + L+ES + NE L + + ++ + + E+E + S +L
Sbjct: 2560 QQNKELENKYAKLEEKLKESEEA----NEDLRRSFNALQEEKQDLSKEIESLKVSISQLT 2615
Query: 629 K 629
+
Sbjct: 2616 R 2616
Score = 39.3 bits (90), Expect = 0.011
Identities = 39/169 (23%), Positives = 74/169 (43%), Gaps = 11/169 (6%)
Query: 449 QARHILSSVEEFTAAQDSSAMVGEDVGSLALESK----SLQSRLAEQQQQHAREMSEVTA 504
+ RHI S VEE + A + + L LE K +LQ + E+ QQ +T
Sbjct: 853 RVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTE 912
Query: 505 ELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSVKRL 564
++ ++E L + K+L+E L S KKE D + +GL+ + +
Sbjct: 913 KMVQLNEEKFSLGVEI-KTLKEQLNLLSRAEEAKKEQVEEDNEVS-----SGLKQNYDEM 966
Query: 565 CGEIVELKQHLEH-YDKIQELTQMLQESHSSLVSTNEHLLQELSQVRAQ 612
K+ L+H +D +++ + + + + + LLQ +S++ +
Sbjct: 967 SPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE 1015
Score = 37.0 bits (84), Expect = 0.057
Identities = 60/282 (21%), Positives = 111/282 (39%), Gaps = 38/282 (13%)
Query: 379 RTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALLETLLDLVDRSWGGCR 438
RT+ E +TE Q+ +T H KK + A + LLD D R
Sbjct: 2040 RTVKALEFVQTESQKDLEITKENLAQAVEHR----KKAQAELASFKVLLD--DTQSEAAR 2093
Query: 439 SLHSNEAFLAQARHILSSVEEFTAAQDSSA--MVGEDVGSLALESKSLQSRL--AEQQQQ 494
L N + + SV+ +D + + E K++Q +L +++
Sbjct: 2094 VLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKV 2153
Query: 495 HARE-MSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSM------------KKEV 541
H E + E+ L+ KE+ L+++LD ++ + + + S+ K E
Sbjct: 2154 HLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWER 2213
Query: 542 KSADTAATLNLQI-------AGLQTSVKRLCGEIVELK---QHLEH-----YDKIQELTQ 586
K +D + +I + L+ ++++ + ELK LEH K Q Q
Sbjct: 2214 KFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQ 2273
Query: 587 MLQESHSSLVSTNEHLLQELSQVRAQHRAEVEQMHWSYQELK 628
+ Q+ +L N+ LL +L + R + + ++ ELK
Sbjct: 2274 LQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELK 2315
Score = 35.8 bits (81), Expect = 0.13
Identities = 38/179 (21%), Positives = 85/179 (47%), Gaps = 18/179 (10%)
Query: 460 FTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQ------HAR------EMSEVTAELH 507
F A Q+ + +++ SL + L ++ Q++ HA+ E+ ++A
Sbjct: 2590 FNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFS 2649
Query: 508 HTHKELDDLRQHLDKSLEENSR-LKSLLLSMKKEVKSAD-TAATLNLQIAGLQTSVKRLC 565
+ K + +L + L +E ++ + + +KKE+K A + + + V L
Sbjct: 2650 SSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELA 2709
Query: 566 GEIVELKQHLEHYDKIQE-LTQMLQE---SHSSLVSTNEHLLQELSQVRAQHRAEVEQM 620
++VE++Q L K + LT +Q S SSL ++ +H +EL +++ ++ A ++++
Sbjct: 2710 RDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKEL 2768
Score = 34.3 bits (77), Expect = 0.37
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 484 LQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKS 543
L+SR + +Q+H EM E T+ + K +L+ D ++NS+L L ++ V+S
Sbjct: 359 LESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKL--LQDKNEQAVQS 416
Query: 544 ADTAATLNLQIAGLQTSVKRLCGEIVELKQH 574
A T L Q+ + + + L+QH
Sbjct: 417 AQTIQQLEDQLQQKSKEISQFLNRL-PLQQH 446
Score = 34.3 bits (77), Expect = 0.37
Identities = 37/170 (21%), Positives = 76/170 (44%), Gaps = 20/170 (11%)
Query: 454 LSSVEEFTAAQDSSAMVGEDVG--SLALESKSLQ-------SRLAEQQQQHAREMSEVTA 504
L +VE+ A+ + + E++ +E KS + S + + Q H E+ + +
Sbjct: 632 LPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKS 691
Query: 505 ELHHT----HKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTAAT-LNLQIAGLQT 559
++ HK + ++LD+ +E S L L+ KK + +A T L+ + L +
Sbjct: 692 QILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLS 751
Query: 560 SVKRLC------GEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHLL 603
VK L ++ +L+ +L ++ + L Q +H +L++ H L
Sbjct: 752 QVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSL 801
Score = 33.1 bits (74), Expect = 0.82
Identities = 49/238 (20%), Positives = 91/238 (38%), Gaps = 30/238 (12%)
Query: 414 KKTALQAALLETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVE-EFTAAQDSSAMVGE 472
+KT +++ + + L+ + G + N++ + + +L + E Q E
Sbjct: 1978 EKTKVESEIRKEYLEKIQ----GAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQE 2033
Query: 473 DVGSLALESKSLQSRLAEQQQ----------QHAREMSEVTAELHHTHKELDDLRQHLDK 522
+ +L K+L+ E Q+ Q + AEL LDD + +
Sbjct: 2034 KISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAAR 2093
Query: 523 SLEENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQ 582
L +N +LK L S K+ VKS Q+ ++R + E +HL+ +Q
Sbjct: 2094 VLADNLKLKKELQSNKESVKS---------QMKQKDEDLERRLEQAEE--KHLKEKKNMQ 2142
Query: 583 ELTQMLQESHSSLVSTNEHLLQELSQVRAQHRAEVEQMHWSYQELKKTMALFPHSSAS 640
E L+ L E + E+ + EV+Q+ + +A F S +S
Sbjct: 2143 EKLDALRREKVHL----EETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSS 2196
Score = 32.3 bits (72), Expect = 1.4
Identities = 35/158 (22%), Positives = 65/158 (41%), Gaps = 15/158 (9%)
Query: 472 EDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKEL----DDLRQHLDKSLEEN 527
ED+ + S Q +L E Q Q +E+ A+L KE +DLR+ + EE
Sbjct: 2538 EDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2597
Query: 528 SRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQEL--- 584
L + S+K + + L Q+ LQ L +LK E ++ L
Sbjct: 2598 QDLSKEIESLKVSI------SQLTRQVTALQEE-GTLGLYHAQLKVKEEEVHRLSALFSS 2650
Query: 585 -TQMLQESHSSLVSTNEHLLQELSQVRAQHRAEVEQMH 621
+ + E LV + +++ ++ + + E++ +H
Sbjct: 2651 SQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLH 2688
Score = 32.3 bits (72), Expect = 1.4
Identities = 48/237 (20%), Positives = 91/237 (38%), Gaps = 50/237 (21%)
Query: 446 FLAQARHILSSVEEFTAAQDSSAM-VGE--------------DVGSLALESKSLQSRLAE 490
F + + I EE Q +A VGE D G + E+++ + R+AE
Sbjct: 2648 FSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAE 2707
Query: 491 ------QQQQH----AREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSL------- 533
+ +Q +E +TA++ + + L+ D + EE LK
Sbjct: 2708 LARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKE 2767
Query: 534 --------LLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQE-- 583
LL+ +++ ++TA ++N + +++L +++ + L H E
Sbjct: 2768 LAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDS 2827
Query: 584 --LTQMLQESHSSLVSTNEHLLQELSQVRAQHR------AEVEQMHWSYQELKKTMA 632
Q ++ +SL + +HL EL + R A+ Q LKK M+
Sbjct: 2828 YNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMS 2884
Score = 31.6 bits (70), Expect = 2.4
Identities = 32/153 (20%), Positives = 65/153 (42%), Gaps = 19/153 (12%)
Query: 490 EQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEE-----NSRLKSLLLSMKKEVKSA 544
E Q+ ++ EL ++ D Q D++L+E ++++K L L K ++ S
Sbjct: 48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTS- 106
Query: 545 DTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDK--------IQELTQMLQESHSSLV 596
LN I ++ + + ++ L +DK I+++ LQE +
Sbjct: 107 -----LNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELIS 161
Query: 597 STNEHLLQELSQVRAQHRAEVEQMHWSYQELKK 629
+ L Q ++ AQ E+E+ Q+L++
Sbjct: 162 TLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQE 194
Score = 31.6 bits (70), Expect = 2.4
Identities = 35/177 (19%), Positives = 75/177 (42%), Gaps = 19/177 (10%)
Query: 450 ARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSE---VTAEL 506
++H SS EE + + E ++ L AEQ Q + EM E + +L
Sbjct: 133 SKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQL 192
Query: 507 HHTHKELDDLRQHLDKSL----------EENSRLKSLLLSMKKEVKSADTAATLNLQIAG 556
+ + L+ L ++ E+++R ++ + + E+ T A + ++
Sbjct: 193 QEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQ 252
Query: 557 LQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHLLQELSQVRAQH 613
++R +L++H E ++ +LQ+ ++ N+ L Q+L Q+ A+H
Sbjct: 253 KLRVLQR------KLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEH 303
Score = 30.0 bits (66), Expect = 6.9
Identities = 39/203 (19%), Positives = 80/203 (39%), Gaps = 15/203 (7%)
Query: 438 RSLHSNEAFLAQARHILSSVEEFTAAQ----------DSSAMVGEDVGSLALESKSLQSR 487
+ L E F++ + LS + AAQ ++ + ED + +++
Sbjct: 190 QQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETE 249
Query: 488 LAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTA 547
+ ++ + R++ E L + +D L+Q L + + N L L M+ E +
Sbjct: 250 MQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRN- 308
Query: 548 ATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHLLQELS 607
T+ + + ++++ E+ E K + +QE L E L S
Sbjct: 309 -TVETEREESKILLEKMELEVAERKLS---FHNLQEEMHHLLEQFEQAGQAQAELESRYS 364
Query: 608 QVRAQHRAEVEQMHWSYQELKKT 630
+ +H+AE+E+ L+KT
Sbjct: 365 ALEQKHKAEMEEKTSHILSLQKT 387
Score = 30.0 bits (66), Expect = 6.9
Identities = 56/259 (21%), Positives = 100/259 (38%), Gaps = 44/259 (16%)
Query: 382 SQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALLETLLDLVDRSWGGCRSLH 441
+Q ETEEQ S ++ TR P ++P K+A A V + + ++
Sbjct: 1790 TQSIPGETEEQDSLSMS-TR---PTCSESVPSAKSANPA---------VSKDFSSHDEIN 1836
Query: 442 SNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLAL--------ESKSLQSRLAEQQ- 492
+ + Q + ++ +EE + E+ + L E K LQ + +
Sbjct: 1837 NYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNL 1896
Query: 493 --QQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTAATL 550
QQ E+S VT +E DDL + L L E L S+ + A
Sbjct: 1897 LNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAE------LNGSIGNYCQDVTDAQIK 1950
Query: 551 NLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVST---------NEH 601
N + ++K+ E+ E KQ L ++E T++ E + N+
Sbjct: 1951 NELLESEMKNLKKCVSELEEEKQQL-----VKEKTKVESEIRKEYLEKIQGAQKEPGNKS 2005
Query: 602 LLQELSQVRAQHRAEVEQM 620
+EL ++ + + EV+Q+
Sbjct: 2006 HAKELQELLKEKQQEVKQL 2024
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 45.4 bits (106), Expect = 2e-04
Identities = 55/272 (20%), Positives = 115/272 (42%), Gaps = 22/272 (8%)
Query: 364 KESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHSALPGKKTALQAALL 423
KE+L +Q+ +R + E + E+ S +T ++ ++ L
Sbjct: 760 KEALGQQERERARQRQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTL 819
Query: 424 ETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSA-----MVGEDVGSLA 478
+ L+L ++W R+ EA+L L EE +D + D+
Sbjct: 820 KQQLELERQAWEAGRT-RKEEAWLLNREQELR--EEIRKGRDKEIELVIHRLEADMALAK 876
Query: 479 LES-KSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSM 537
ES K+ +SR+ + ++ E+SE+ + +L+ L ++ EN RL+ L +
Sbjct: 877 EESEKAAESRIKRLRDKYEAELSELEQSERKLQERCSELKGQLGEAEGENLRLQGL---V 933
Query: 538 KKEVKSADTAATLNLQIAGLQTSV---------KRLCGEIVELKQHLEHYDKIQELTQM- 587
+++ ++ + A +N Q++ ++++ RL E +Q +Q Q+
Sbjct: 934 RQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAELATLQARQQLE 993
Query: 588 LQESHSSLVSTNEHLLQELSQVRAQHRAEVEQ 619
L+E H + + + +S +R QH A V++
Sbjct: 994 LEEVHRRVKTALARKEEAVSSLRTQHEAAVKR 1025
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,083,552
Number of Sequences: 37866
Number of extensions: 1206715
Number of successful extensions: 6582
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 603
Number of HSP's that attempted gapping in prelim test: 5412
Number of HSP's gapped (non-prelim): 1688
length of query: 647
length of database: 18,247,518
effective HSP length: 109
effective length of query: 538
effective length of database: 14,120,124
effective search space: 7596626712
effective search space used: 7596626712
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.