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Search of human proteins with 62865606
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62865606 tripartite motif-containing 36 isoform 1 [Homo
sapiens]
(728 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 1496 0.0
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 619 e-177
gi|148833499 midline 1 [Homo sapiens] 230 4e-60
gi|4557753 midline 1 [Homo sapiens] 230 4e-60
gi|15451852 midline 1 [Homo sapiens] 230 4e-60
gi|223890259 midline 2 isoform 2 [Homo sapiens] 217 3e-56
gi|223890257 midline 2 isoform 1 [Homo sapiens] 217 4e-56
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens] 201 2e-51
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] 190 5e-48
gi|134288906 tripartite motif-containing 67 [Homo sapiens] 165 1e-40
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 154 2e-37
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 154 2e-37
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 154 2e-37
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] 150 4e-36
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] 146 6e-35
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 130 4e-30
gi|89886468 fibronectin type III and SPRY domain containing 1-li... 115 1e-25
gi|223718222 fibronectin type III and SPRY domain containing 1-l... 114 3e-25
gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens] 110 5e-24
gi|28195390 tripartite motif-containing 42 [Homo sapiens] 108 1e-23
gi|13236585 fibronectin type III and SPRY domain containing 1 [H... 101 2e-21
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi... 97 5e-20
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi... 97 5e-20
gi|148596968 tripartite motif-containing 8 [Homo sapiens] 95 2e-19
gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 82 2e-15
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 78 3e-14
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 77 7e-14
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 77 7e-14
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam... 72 1e-12
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet... 72 1e-12
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 1496 bits (3874), Expect = 0.0
Identities = 728/728 (100%), Positives = 728/728 (100%)
Query: 1 MSESGEMSEFGYIMELIAKGKVTIKNIERELICPACKELFTHPLILPCQHSICHKCVKEL 60
MSESGEMSEFGYIMELIAKGKVTIKNIERELICPACKELFTHPLILPCQHSICHKCVKEL
Sbjct: 1 MSESGEMSEFGYIMELIAKGKVTIKNIERELICPACKELFTHPLILPCQHSICHKCVKEL 60
Query: 61 LLTLDDSFNDVGSDNSNQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEH 120
LLTLDDSFNDVGSDNSNQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEH
Sbjct: 61 LLTLDDSFNDVGSDNSNQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEH 120
Query: 121 DVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCN 180
DVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCN
Sbjct: 121 DVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCN 180
Query: 181 ECFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGN 240
ECFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGN
Sbjct: 181 ECFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGN 240
Query: 241 HANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAI 300
HANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAI
Sbjct: 241 HANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAI 300
Query: 301 THFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENNGLVGYAQEVLKETD 360
THFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENNGLVGYAQEVLKETD
Sbjct: 301 THFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENNGLVGYAQEVLKETD 360
Query: 361 QSCFVQTAKQLHLRIQKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVP 420
QSCFVQTAKQLHLRIQKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVP
Sbjct: 361 QSCFVQTAKQLHLRIQKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVP 420
Query: 421 EINEEQSKVYNNALINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEVCGTSKIIQDLEN 480
EINEEQSKVYNNALINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEVCGTSKIIQDLEN
Sbjct: 421 EINEEQSKVYNNALINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEVCGTSKIIQDLEN 480
Query: 481 SSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVESR 540
SSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVESR
Sbjct: 481 SSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVESR 540
Query: 541 AGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVEPYSYLVKVGVASSDKLQEW 600
AGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVEPYSYLVKVGVASSDKLQEW
Sbjct: 541 AGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVEPYSYLVKVGVASSDKLQEW 600
Query: 601 LRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMQKFFIPKSPTSSNEPENRVL 660
LRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMQKFFIPKSPTSSNEPENRVL
Sbjct: 601 LRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMQKFFIPKSPTSSNEPENRVL 660
Query: 661 PMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLYPAFALMGSGGIQLEEPITAK 720
PMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLYPAFALMGSGGIQLEEPITAK
Sbjct: 661 PMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLYPAFALMGSGGIQLEEPITAK 720
Query: 721 YLEYQEDM 728
YLEYQEDM
Sbjct: 721 YLEYQEDM 728
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 619 bits (1596), Expect = e-177
Identities = 318/749 (42%), Positives = 468/749 (62%), Gaps = 33/749 (4%)
Query: 1 MSESGEMSEFGYIMELIAKGKVTIKNIERELICPACKELFTHPLILPCQHSICHKCVKEL 60
M+E +M F IM+ + + ++KN+E+EL+CP C+E++ PL+LPC H++C C +E+
Sbjct: 1 MAEGEDMQTFTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREV 60
Query: 61 LLTLDDSFNDVGSDNSNQS----------SPRL-RLPSPSMDKIDRINR------PGWKR 103
L + G D S++ SPRL R P D++DR+ + PG KR
Sbjct: 61 LG--QQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKR 118
Query: 104 NSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPP 163
+L P+ +FPCP C+ DV+LGERG+ GLFRN TLE +VERYRQ+ AI+C LCKPP
Sbjct: 119 GALHPQVIMFPCPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPP 178
Query: 164 PQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMY 223
P E+TK C +C A++CNECFK+ HPWGT KAQHE PT +FRPK LMCP+H+ E + Y
Sbjct: 179 PLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHK-EEVTHY 237
Query: 224 CELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNL 283
C+ C+R VC LC++ H+ H++T + SAY+ LK+KL+K + Y++G + V++QI EL
Sbjct: 238 CKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEE 297
Query: 284 LMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLL 343
++ TE +G++AKEE L VLEE+++S+L+AI+ ++ RL + Q++E++ LL
Sbjct: 298 AVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLL 357
Query: 344 ENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRPAAQTSFEDYVVNTSKQ 403
+ +GLVGYAQEVLKETDQ CFVQ AKQLH RI +ATE+L++FRPAA +SF ++ ++
Sbjct: 358 DGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGRE 417
Query: 404 TELLGELSFFSSGIDVPEINEEQSKVYNNALINWH-HPEKDKADSYVLEYRKIN---RDD 459
+LL EL+F + P I+ +++ Y+ + W P A Y +E+R+ + +
Sbjct: 418 MKLLTELNFLRVP-EAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPAQPG 476
Query: 460 EMSW-NEIEVCGTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFD 518
W EV GTS ++++ + S Y RVR + S ++ LHTPPAPV F D
Sbjct: 477 PTRWQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLD 536
Query: 519 EKCGYNNEHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAF 578
+ G + E L ++ + V S G LLLAA+R+ G + S+D ++GD +T+G+ +WA
Sbjct: 537 SRWGASRERLAISKDQRAVRSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWAC 596
Query: 579 RVEPYSYLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTI 638
V+P SYLVKVGV KLQE + D +SPRY+ DSGHDSG+EDA ++S PF +TI
Sbjct: 597 AVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTI 656
Query: 639 GMQKFFIPKSPTSSNEPENR-------VLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYER 691
GM K + +S+ R +P+P +GI LD ++G+V F D + L E
Sbjct: 657 GMGKILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLEC 716
Query: 692 QVDCSHTLYPAFALMGSGGIQLEEPITAK 720
+DCS + PAF +G G +QL+EP+ K
Sbjct: 717 PLDCSGPVCPAFCFIGGGAVQLQEPVGTK 745
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 230 bits (586), Expect = 4e-60
Identities = 183/725 (25%), Positives = 308/725 (42%), Gaps = 125/725 (17%)
Query: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRL 83
++ +E EL CP C ELF PL+LPC HS+C C +L V +N+S +
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRIL---------VSHCATNESVESI 51
Query: 84 RLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVE 143
T F CP C H + L +RG++GL RN TL+ I++
Sbjct: 52 ---------------------------TAFQCPTCRHVITLSQRGLDGLKRNVTLQNIID 84
Query: 144 RYRQAA---------------------RAATAIMCDLC-KPPPQESTKSCMDCSASYCNE 181
R+++A+ +A ++C C + P Q++ K+C+ C SYC+E
Sbjct: 85 RFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDE 144
Query: 182 CFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNH 241
C K HP H + P + + LMC EHE E++NMYC + +C LCKL G H
Sbjct: 145 CLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRH 204
Query: 242 ANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAIT 301
+H+V +S Y LK+ L ++ LI + +++++ +++L + E N R + +
Sbjct: 205 RDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTE 264
Query: 302 HFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETD 360
+ L E++++R+ + I K +RL K Q+ + +E + L+ A+ LKE D
Sbjct: 265 ECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKEND 324
Query: 361 QSCFVQTAKQLHLRIQKATESLKSFRPA--AQTSFEDYVVNTSKQTELLGELSFFSSGID 418
+ F+QTAK + R+ AT S + P +F+ + ++ S++ +LL L + ++ +
Sbjct: 325 HARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAP-N 383
Query: 419 VPEINEEQ-SKVYNNALINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEVCGTSK---- 473
P I EE + Y+ ++W ++ SY L+Y N + +C ++
Sbjct: 384 PPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQA----NVVSLCNSADSWMI 439
Query: 474 ---------IIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYN 524
+ L++ + Y F V+A S S L T P F D K +
Sbjct: 440 VPNIKQNHYTVHGLQSGTKYIFMVKAI-NQAGSRSSEPGKLKTNSQP---FKLDPKSAHR 495
Query: 525 N---EHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVE 581
H L ++RD S+ + G + G+ I G+H+W +
Sbjct: 496 KLKVSHDNLTVERDESSSKKSHTPERFTSQGSYG-------VAGNVFIDSGRHYWEVVIS 548
Query: 582 PYS-YLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGM 640
+ Y + + S+ K EW+ G +S S C ++ +
Sbjct: 549 GSTWYAIGLAYKSAPK-HEWI---------------GKNSASWALCRCNNN----WVVRH 588
Query: 641 QKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLY 700
IP P P +GI LD D G + FYD LY V + +
Sbjct: 589 NSKEIPIEPA----------PHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC 638
Query: 701 PAFAL 705
P F +
Sbjct: 639 PTFTV 643
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 230 bits (586), Expect = 4e-60
Identities = 183/725 (25%), Positives = 308/725 (42%), Gaps = 125/725 (17%)
Query: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRL 83
++ +E EL CP C ELF PL+LPC HS+C C +L V +N+S +
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRIL---------VSHCATNESVESI 51
Query: 84 RLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVE 143
T F CP C H + L +RG++GL RN TL+ I++
Sbjct: 52 ---------------------------TAFQCPTCRHVITLSQRGLDGLKRNVTLQNIID 84
Query: 144 RYRQAA---------------------RAATAIMCDLC-KPPPQESTKSCMDCSASYCNE 181
R+++A+ +A ++C C + P Q++ K+C+ C SYC+E
Sbjct: 85 RFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDE 144
Query: 182 CFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNH 241
C K HP H + P + + LMC EHE E++NMYC + +C LCKL G H
Sbjct: 145 CLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRH 204
Query: 242 ANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAIT 301
+H+V +S Y LK+ L ++ LI + +++++ +++L + E N R + +
Sbjct: 205 RDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTE 264
Query: 302 HFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETD 360
+ L E++++R+ + I K +RL K Q+ + +E + L+ A+ LKE D
Sbjct: 265 ECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKEND 324
Query: 361 QSCFVQTAKQLHLRIQKATESLKSFRPA--AQTSFEDYVVNTSKQTELLGELSFFSSGID 418
+ F+QTAK + R+ AT S + P +F+ + ++ S++ +LL L + ++ +
Sbjct: 325 HARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAP-N 383
Query: 419 VPEINEEQ-SKVYNNALINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEVCGTSK---- 473
P I EE + Y+ ++W ++ SY L+Y N + +C ++
Sbjct: 384 PPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQA----NVVSLCNSADSWMI 439
Query: 474 ---------IIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYN 524
+ L++ + Y F V+A S S L T P F D K +
Sbjct: 440 VPNIKQNHYTVHGLQSGTKYIFMVKAI-NQAGSRSSEPGKLKTNSQP---FKLDPKSAHR 495
Query: 525 N---EHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVE 581
H L ++RD S+ + G + G+ I G+H+W +
Sbjct: 496 KLKVSHDNLTVERDESSSKKSHTPERFTSQGSYG-------VAGNVFIDSGRHYWEVVIS 548
Query: 582 PYS-YLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGM 640
+ Y + + S+ K EW+ G +S S C ++ +
Sbjct: 549 GSTWYAIGLAYKSAPK-HEWI---------------GKNSASWALCRCNNN----WVVRH 588
Query: 641 QKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLY 700
IP P P +GI LD D G + FYD LY V + +
Sbjct: 589 NSKEIPIEPA----------PHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC 638
Query: 701 PAFAL 705
P F +
Sbjct: 639 PTFTV 643
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 230 bits (586), Expect = 4e-60
Identities = 183/725 (25%), Positives = 308/725 (42%), Gaps = 125/725 (17%)
Query: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRL 83
++ +E EL CP C ELF PL+LPC HS+C C +L V +N+S +
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRIL---------VSHCATNESVESI 51
Query: 84 RLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVE 143
T F CP C H + L +RG++GL RN TL+ I++
Sbjct: 52 ---------------------------TAFQCPTCRHVITLSQRGLDGLKRNVTLQNIID 84
Query: 144 RYRQAA---------------------RAATAIMCDLC-KPPPQESTKSCMDCSASYCNE 181
R+++A+ +A ++C C + P Q++ K+C+ C SYC+E
Sbjct: 85 RFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDE 144
Query: 182 CFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNH 241
C K HP H + P + + LMC EHE E++NMYC + +C LCKL G H
Sbjct: 145 CLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRH 204
Query: 242 ANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAIT 301
+H+V +S Y LK+ L ++ LI + +++++ +++L + E N R + +
Sbjct: 205 RDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTE 264
Query: 302 HFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETD 360
+ L E++++R+ + I K +RL K Q+ + +E + L+ A+ LKE D
Sbjct: 265 ECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKEND 324
Query: 361 QSCFVQTAKQLHLRIQKATESLKSFRPA--AQTSFEDYVVNTSKQTELLGELSFFSSGID 418
+ F+QTAK + R+ AT S + P +F+ + ++ S++ +LL L + ++ +
Sbjct: 325 HARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAP-N 383
Query: 419 VPEINEEQ-SKVYNNALINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEVCGTSK---- 473
P I EE + Y+ ++W ++ SY L+Y N + +C ++
Sbjct: 384 PPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQA----NVVSLCNSADSWMI 439
Query: 474 ---------IIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYN 524
+ L++ + Y F V+A S S L T P F D K +
Sbjct: 440 VPNIKQNHYTVHGLQSGTKYIFMVKAI-NQAGSRSSEPGKLKTNSQP---FKLDPKSAHR 495
Query: 525 N---EHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVE 581
H L ++RD S+ + G + G+ I G+H+W +
Sbjct: 496 KLKVSHDNLTVERDESSSKKSHTPERFTSQGSYG-------VAGNVFIDSGRHYWEVVIS 548
Query: 582 PYS-YLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGM 640
+ Y + + S+ K EW+ G +S S C ++ +
Sbjct: 549 GSTWYAIGLAYKSAPK-HEWI---------------GKNSASWALCRCNNN----WVVRH 588
Query: 641 QKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLY 700
IP P P +GI LD D G + FYD LY V + +
Sbjct: 589 NSKEIPIEPA----------PHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVC 638
Query: 701 PAFAL 705
P F +
Sbjct: 639 PTFTV 643
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 217 bits (553), Expect = 3e-56
Identities = 162/616 (26%), Positives = 284/616 (46%), Gaps = 86/616 (13%)
Query: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRL 83
++ +E EL CP C ELF PL+LPC HS+C C +L V S +S +S +
Sbjct: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRIL---------VSSCSSGESIEPI 71
Query: 84 RLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVE 143
T F CP C + + L RG++GL RN TL+ I++
Sbjct: 72 ---------------------------TAFQCPTCRYVISLNHRGLDGLKRNVTLQNIID 104
Query: 144 RYRQAA----------------RAATA-----IMCDLCKP-PPQESTKSCMDCSASYCNE 181
R+++A+ R TA I C C+ PP+++ K+C+ C SYC+
Sbjct: 105 RFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDR 164
Query: 182 CFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNH 241
C + HP H V P + + + C +HE E++NMYC + +C LCKL G H
Sbjct: 165 CLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRH 224
Query: 242 ANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAIT 301
+H+V +++ ++ LK+ L ++ L+ + S++++Q+++L + ++ E N + + +
Sbjct: 225 RDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLME 284
Query: 302 HFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENNG-LVGYAQEVLKETD 360
++L E++++RK + I +K ++L K Q+ + LE + L+ A+ +LKE D
Sbjct: 285 ECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKEND 344
Query: 361 QSCFVQTAKQLHLRIQKATESLKSFRPAA--QTSFEDYVVNTSKQTELLGELSFFSSGID 418
Q+ F+Q+AK + R+ AT S + P +FE++ ++ S++ +LL L + ++ +
Sbjct: 345 QARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAP-N 403
Query: 419 VPEINEEQSKVYNNAL-INWHHPEKDKADSYVLEYRKINRDDEM--------SWNEI-EV 468
P I EE ++ + ++W ++ SY L+Y SW + +
Sbjct: 404 PPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQANFISLYNSVDSWMIVPNI 463
Query: 469 CGTSKIIQDLENSSTYAFRVRAYK--GSICSPCSRELILHTPPAPVFSFLFDEKCGYNNE 526
+ L++ + Y F V+A GS S +R L T P F D K
Sbjct: 464 KQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTR---LKTNSQP---FKLDPKM----T 513
Query: 527 HLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVEPYSYL 586
H L + D ++ + L + + T G+ I G H+W V S
Sbjct: 514 HKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEV-VMGSSTW 572
Query: 587 VKVGVA-SSDKLQEWL 601
+G+A S EW+
Sbjct: 573 YAIGIAYKSAPKNEWI 588
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 217 bits (552), Expect = 4e-56
Identities = 128/455 (28%), Positives = 231/455 (50%), Gaps = 63/455 (13%)
Query: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRL 83
++ +E EL CP C ELF PL+LPC HS+C C +L V S +S +S +
Sbjct: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRIL---------VSSCSSGESIEPI 71
Query: 84 RLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVE 143
T F CP C + + L RG++GL RN TL+ I++
Sbjct: 72 ---------------------------TAFQCPTCRYVISLNHRGLDGLKRNVTLQNIID 104
Query: 144 RYRQAA----------------RAATA-----IMCDLCKP-PPQESTKSCMDCSASYCNE 181
R+++A+ R TA I C C+ PP+++ K+C+ C SYC+
Sbjct: 105 RFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDR 164
Query: 182 CFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNH 241
C + HP H V P + + + C +HE E++NMYC + +C LCKL G H
Sbjct: 165 CLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRH 224
Query: 242 ANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAIT 301
+H+V +++ ++ LK+ L ++ L+ + S++++Q+++L + ++ E N + + +
Sbjct: 225 RDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLME 284
Query: 302 HFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENNG-LVGYAQEVLKETD 360
++L E++++RK + I +K ++L K Q+ + LE + L+ A+ +LKE D
Sbjct: 285 ECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKEND 344
Query: 361 QSCFVQTAKQLHLRIQKATESLKSFRPAA--QTSFEDYVVNTSKQTELLGELSFFSSGID 418
Q+ F+Q+AK + R+ AT S + P +FE++ ++ S++ +LL L + ++ +
Sbjct: 345 QARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAP-N 403
Query: 419 VPEINEEQSKVYNNAL-INWHHPEKDKADSYVLEY 452
P I EE ++ + ++W ++ SY L+Y
Sbjct: 404 PPSIREELCTASHDTITVHWISDDEFSISSYELQY 438
>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
Length = 710
Score = 201 bits (512), Expect = 2e-51
Identities = 158/619 (25%), Positives = 276/619 (44%), Gaps = 90/619 (14%)
Query: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTL------------------- 64
++ +E EL CP C + P+ILPC H++C C + +L+
Sbjct: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60
Query: 65 --------------DDSFNDVGSDNSNQSSPRLRLPS------PSMDKIDRINRPGWKRN 104
D + G S ++P + P+ P+M P
Sbjct: 61 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPAL--- 117
Query: 105 SLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPPP 164
+ PR + CP C + L +RG+ G +N LE +++RY+Q+ A A+ C LC+ P
Sbjct: 118 APVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK--AAALKCQLCEKAP 175
Query: 165 QESTKSCMDCSASYCNEC-FKIHHPWGTIKAQHEYVGP-----TTNFRP-KILMCPEHET 217
+E+T C C YC+ C + H P G + A+H V P + P K+ C +HE
Sbjct: 176 KEATVMCEQCDVFYCDPCRLRCHPPRGPL-AKHRLVPPAQGRVSRRLSPRKVSTCTDHEL 234
Query: 218 ERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQ 277
E +MYC C+ PVC+ C G H++H V + + +K K +LS+ ++ L + + K
Sbjct: 235 ENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEF 294
Query: 278 ISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQME 337
+ +L ++++ + N + + + L + L RK+ +L ++ + +L + Q+
Sbjct: 295 LVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQIS 354
Query: 338 EYQ-GLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATE--SLKSFRPAAQTSFE 394
L + GL+ Y EV+KE D S F+Q + L R+ + + P T F
Sbjct: 355 HCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDF- 413
Query: 395 DYVVNTSKQTELLGELSFF----SSGID-VPEINEEQSKVYNN-ALINWHHPEKD--KAD 446
D ++ S + + +L F SS + P + E+ +NN A ++W P AD
Sbjct: 414 DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPAD 473
Query: 447 SYVLEYRKINRDDEMSWNEIEV-CGTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELIL 505
Y+LE ++ + + E+ V T + L +STY RV+A+ + SP S+ L+L
Sbjct: 474 GYILE---LDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVL 530
Query: 506 HTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLD-YII 564
T + V F FD ++ +++L+ + + V + D ++
Sbjct: 531 QT--SEVAWFAFDPGSAHS-------------------DIILSNDNLTVTCSSYDDRVVL 569
Query: 565 GDTGITKGKHFWAFRVEPY 583
G TG +KG H+W V+ Y
Sbjct: 570 GKTGFSKGIHYWELTVDRY 588
>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
Length = 550
Score = 190 bits (482), Expect = 5e-48
Identities = 142/542 (26%), Positives = 245/542 (45%), Gaps = 68/542 (12%)
Query: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTL------------------- 64
++ +E EL CP C + P+ILPC H++C C + +L+
Sbjct: 1 MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESESPQSHRAAGSGVSDY 60
Query: 65 --------------DDSFNDVGSDNSNQSSPRLRLPS------PSMDKIDRINRPGWKRN 104
D + G S ++P + P+ P+M P
Sbjct: 61 DYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVFPPAMPPPATHLSPAL--- 117
Query: 105 SLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAARAATAIMCDLCKPPP 164
+ PR + CP C + L +RG+ G +N LE +++RY+Q+ A A+ C LC+ P
Sbjct: 118 APVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSK--AAALKCQLCEKAP 175
Query: 165 QESTKSCMDCSASYCNEC-FKIHHPWGTIKAQHEYVGP-----TTNFRP-KILMCPEHET 217
+E+T C C YC+ C + H P G + A+H V P + P K+ C +HE
Sbjct: 176 KEATVMCEQCDVFYCDPCRLRCHPPRGPL-AKHRLVPPAQGRVSRRLSPRKVSTCTDHEL 234
Query: 218 ERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQ 277
E +MYC C+ PVC+ C G H++H V + + +K K +LS+ ++ L + + K
Sbjct: 235 ENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNGLSDRAKEAKEF 294
Query: 278 ISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQME 337
+ +L ++++ + N + + + L + L RK+ +L ++ + +L + Q+
Sbjct: 295 LVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHEHKLKVVRDQIS 354
Query: 338 EYQ-GLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATE--SLKSFRPAAQTSFE 394
L + GL+ Y EV+KE D S F+Q + L R+ + + P T F
Sbjct: 355 HCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKGTLTPRMTTDF- 413
Query: 395 DYVVNTSKQTELLGELSFF----SSGID-VPEINEEQSKVYNN-ALINWHHPEKD--KAD 446
D ++ S + + +L F SS + P + E+ +NN A ++W P AD
Sbjct: 414 DLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATLSWKQPPLSTVPAD 473
Query: 447 SYVLEYRKINRDDEMSWNEIEV-CGTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELIL 505
Y+LE ++ + + E+ V T + L +STY RV+A+ + SP S+ L+L
Sbjct: 474 GYILE---LDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNKTGVSPYSKTLVL 530
Query: 506 HT 507
T
Sbjct: 531 QT 532
>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
Length = 783
Score = 165 bits (418), Expect = 1e-40
Identities = 138/541 (25%), Positives = 220/541 (40%), Gaps = 89/541 (16%)
Query: 104 NSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQA-------ARAATAIM 156
+SL+ ++ CP C L RG+ G RN LE IV+RY+Q + AA +
Sbjct: 148 SSLSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAI 207
Query: 157 CDLC-KPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGPTTNFRP-------- 207
C LC + PP+ + C C YC+ C HP A+H V P P
Sbjct: 208 CQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGP 267
Query: 208 -------------------------------KILMCPEHETERINMYCELCRRPVCHLCK 236
K CPEHE E +MYC CR PVC+LC
Sbjct: 268 TGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEMENYSMYCVSCRTPVCYLCL 327
Query: 237 LGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAK 296
G HA H V + + +K K +LS+ ++ + K + K + +L ++++ + NG +
Sbjct: 328 EEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYE 387
Query: 297 EEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQ-GLLENNGLVGYAQEV 355
+ + L + L +K+ +L + ++ +L Q+ L ++ GL+ Y EV
Sbjct: 388 ACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEV 447
Query: 356 LKETDQSCFVQTAKQLHLRIQKATES--LKSFRPAAQTSFEDYVVNTSKQTELLGELSFF 413
+KE D S F+Q + L R+Q + E + P F D +++ + + +L F
Sbjct: 448 IKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEF-DLTLDSEPLLQAIHQLDFI 506
Query: 414 SSGIDVPEIN----EEQSKVYNNALINWHHP--EKDKADSYVLEYRKINRDDEMSWNEIE 467
VP + E+ N+ + W P D Y+LE DD E
Sbjct: 507 QMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVDGYILEL-----DDGAGGQFRE 561
Query: 468 VC---GTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYN 524
V T I L +STY RV+A+ S P S+ ++L T + V F FD G+
Sbjct: 562 VYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQT--SDVAWFTFDPNSGHR 619
Query: 525 NEHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLD--YIIGDTGITKGKHFWAFRVEP 582
+ ++ + Q +S D ++G +KG H+W V+
Sbjct: 620 D--------------------IILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDR 659
Query: 583 Y 583
Y
Sbjct: 660 Y 660
Score = 46.6 bits (109), Expect = 8e-05
Identities = 17/40 (42%), Positives = 24/40 (60%)
Query: 27 IERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDD 66
+E EL CP C LF P+ILPC H++C C + + + D
Sbjct: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPD 40
>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
Length = 452
Score = 154 bits (390), Expect = 2e-37
Identities = 112/410 (27%), Positives = 187/410 (45%), Gaps = 91/410 (22%)
Query: 18 AKGKVTIKNIERELICPACKELFTHPL-ILPCQHSICHKCVKELLLTLDDSFNDVGSDNS 76
+K + T+ N+E++LICP C E+FT P+ ILPCQH++C KC SD
Sbjct: 11 SKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCA---------------SDIF 55
Query: 77 NQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNF 136
S+P L P+ + R F CP C H+V L G+ GL RN
Sbjct: 56 QASNPYL--PTRGGTTMASGGR--------------FRCPSCRHEVVLDRHGVYGLQRNL 99
Query: 137 TLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQH 196
+E I++ Y+Q + P ++S +
Sbjct: 100 LVENIIDIYKQESTR-----------PEKKSDQP-------------------------- 122
Query: 197 EYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTL 256
MC EHE ERIN+YC C P C LCK+ G H + +V ++ ++
Sbjct: 123 --------------MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQ 168
Query: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSS 316
K +LS I L+G +V+ IS+L K E + K+E F+ L+ +LEERK+
Sbjct: 169 KSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNE 228
Query: 317 VLKAIDSSKKLRLDKFQTQMEEYQGLLEN-NGLVGYAQEVLKETDQSCFVQTAKQLHLRI 375
+ + I +++ +L+ + +++Y LEN + LV + + E + + F+Q AK L +
Sbjct: 229 MTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTL---L 285
Query: 376 QKATESLKSFR----PAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPE 421
+K +E+ K+F+ + + VN +++ +++ E+ F+ D E
Sbjct: 286 KKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEE 335
>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
Length = 548
Score = 154 bits (390), Expect = 2e-37
Identities = 112/410 (27%), Positives = 187/410 (45%), Gaps = 91/410 (22%)
Query: 18 AKGKVTIKNIERELICPACKELFTHPL-ILPCQHSICHKCVKELLLTLDDSFNDVGSDNS 76
+K + T+ N+E++LICP C E+FT P+ ILPCQH++C KC SD
Sbjct: 11 SKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCA---------------SDIF 55
Query: 77 NQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNF 136
S+P L P+ + R F CP C H+V L G+ GL RN
Sbjct: 56 QASNPYL--PTRGGTTMASGGR--------------FRCPSCRHEVVLDRHGVYGLQRNL 99
Query: 137 TLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQH 196
+E I++ Y+Q + P ++S +
Sbjct: 100 LVENIIDIYKQESTR-----------PEKKSDQP-------------------------- 122
Query: 197 EYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTL 256
MC EHE ERIN+YC C P C LCK+ G H + +V ++ ++
Sbjct: 123 --------------MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQ 168
Query: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSS 316
K +LS I L+G +V+ IS+L K E + K+E F+ L+ +LEERK+
Sbjct: 169 KSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNE 228
Query: 317 VLKAIDSSKKLRLDKFQTQMEEYQGLLEN-NGLVGYAQEVLKETDQSCFVQTAKQLHLRI 375
+ + I +++ +L+ + +++Y LEN + LV + + E + + F+Q AK L +
Sbjct: 229 MTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTL---L 285
Query: 376 QKATESLKSFR----PAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPE 421
+K +E+ K+F+ + + VN +++ +++ E+ F+ D E
Sbjct: 286 KKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEE 335
>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
Length = 540
Score = 154 bits (390), Expect = 2e-37
Identities = 112/410 (27%), Positives = 187/410 (45%), Gaps = 91/410 (22%)
Query: 18 AKGKVTIKNIERELICPACKELFTHPL-ILPCQHSICHKCVKELLLTLDDSFNDVGSDNS 76
+K + T+ N+E++LICP C E+FT P+ ILPCQH++C KC SD
Sbjct: 11 SKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCA---------------SDIF 55
Query: 77 NQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNF 136
S+P L P+ + R F CP C H+V L G+ GL RN
Sbjct: 56 QASNPYL--PTRGGTTMASGGR--------------FRCPSCRHEVVLDRHGVYGLQRNL 99
Query: 137 TLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQH 196
+E I++ Y+Q + P ++S +
Sbjct: 100 LVENIIDIYKQESTR-----------PEKKSDQP-------------------------- 122
Query: 197 EYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTL 256
MC EHE ERIN+YC C P C LCK+ G H + +V ++ ++
Sbjct: 123 --------------MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQ 168
Query: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSS 316
K +LS I L+G +V+ IS+L K E + K+E F+ L+ +LEERK+
Sbjct: 169 KSELSDGIAILVGSNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNE 228
Query: 317 VLKAIDSSKKLRLDKFQTQMEEYQGLLEN-NGLVGYAQEVLKETDQSCFVQTAKQLHLRI 375
+ + I +++ +L+ + +++Y LEN + LV + + E + + F+Q AK L +
Sbjct: 229 MTQVITRTQEEKLEHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTL---L 285
Query: 376 QKATESLKSFR----PAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPE 421
+K +E+ K+F+ + + VN +++ +++ E+ F+ D E
Sbjct: 286 KKISEASKAFQMEKIEHGYENMNHFTVNLNREEKIIREIDFYREDEDEEE 335
>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
Length = 358
Score = 150 bits (379), Expect = 4e-36
Identities = 112/427 (26%), Positives = 187/427 (43%), Gaps = 89/427 (20%)
Query: 23 TIKNIERELICPACKELFTHPL-ILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSP 81
++ N+E++LICP C E+F+ P+ ILPCQH++C KC ++ + + GS +
Sbjct: 16 SMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGR 75
Query: 82 RLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETI 141
F CP C H+V L G+ GL RN +E I
Sbjct: 76 -------------------------------FRCPSCRHEVVLDRHGVYGLQRNLLVENI 104
Query: 142 VERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGP 201
++ Y+Q ES++ P + QH
Sbjct: 105 IDIYKQ------------------ESSR------------------PLHSKAEQH----- 123
Query: 202 TTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLS 261
LMC EHE E+IN+YC C P C LCK+ G H + V + + YK K +LS
Sbjct: 124 --------LMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELS 175
Query: 262 KDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAI 321
I L+ +V++ I+++ + + E N R K+ FE L VLEERK +L+A+
Sbjct: 176 DGIAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQAL 235
Query: 322 DSSKKLRLDKFQTQMEEYQGLLE-NNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATE 380
++ +L + + + +Y LE ++ LV A + ++E + ++Q AK+L ++ ++
Sbjct: 236 AREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSK 295
Query: 381 SLKSFRP-AAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNALINWHH 439
+ RP S E + V E+L + F P + E+ +V +
Sbjct: 296 VELAGRPEPGYESMEQFTVRVEHVAEMLRTIDF------QPGASGEEEEVAPDGEEGSAG 349
Query: 440 PEKDKAD 446
PE+++ D
Sbjct: 350 PEEERPD 356
>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
Length = 353
Score = 146 bits (369), Expect = 6e-35
Identities = 105/371 (28%), Positives = 166/371 (44%), Gaps = 84/371 (22%)
Query: 12 YIMELIAKGKVTIKNIERELICPACKELFTHPL-ILPCQHSICHKCVKELLLTLDDSFND 70
Y LI G ++N+E++LICP C E+FT P+ ILPCQH++C KC ++ + +
Sbjct: 3 YKSSLIQDGN-PMENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTS 61
Query: 71 VGSDNSNQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGIN 130
GS S S R R CP C H+V + G+
Sbjct: 62 RGSSVS-MSGGRFR------------------------------CPTCRHEVIMDRHGVY 90
Query: 131 GLFRNFTLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWG 190
GL RN +E I++ Y+Q C P + K HP
Sbjct: 91 GLQRNLLVENIIDIYKQE-----------CSSRPLQ-----------------KGSHP-- 120
Query: 191 TIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMS 250
MC EHE E+IN+YC C P C +CK+ G H V +
Sbjct: 121 --------------------MCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQ 160
Query: 251 SAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVL 310
S ++ K +L+ I L+ +V++ I++L + T+ N + KEE F+ L+ +L
Sbjct: 161 SVFQGQKTELNNCISMLVAGNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAIL 220
Query: 311 EERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLE-NNGLVGYAQEVLKETDQSCFVQTAK 369
+E+KS +L+ I ++ +L + +++YQ L+ + LV A + L E + F+ TAK
Sbjct: 221 DEKKSELLQRITQEQEKKLSFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAK 280
Query: 370 QLHLRIQKATE 380
QL I +A++
Sbjct: 281 QLIKSIVEASK 291
>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
Length = 400
Score = 130 bits (327), Expect = 4e-30
Identities = 112/469 (23%), Positives = 188/469 (40%), Gaps = 131/469 (27%)
Query: 23 TIKNIERELICPACKELFTHPL-ILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSP 81
++ N+E++LICP C E+F+ P+ ILPCQH++C KC ++ + + GS +
Sbjct: 16 SMDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGR 75
Query: 82 RLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETI 141
F CP C H+V L G+ GL RN +E I
Sbjct: 76 -------------------------------FRCPSCRHEVVLDRHGVYGLQRNLLVENI 104
Query: 142 VERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGP 201
++ Y+Q ES++ P + QH
Sbjct: 105 IDIYKQ------------------ESSR------------------PLHSKAEQH----- 123
Query: 202 TTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEK-- 259
LMC EHE E+IN+YC C P C LCK+ G H + V + + YK K++
Sbjct: 124 --------LMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDL 175
Query: 260 ----------------------------------------LSKDIDYLIGKESQVKSQIS 279
LS I L+ +V++ I+
Sbjct: 176 TLLPRLECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVIT 235
Query: 280 ELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEY 339
++ + + E N R K+ FE L VLEERK +L+A+ ++ +L + + + +Y
Sbjct: 236 QMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQY 295
Query: 340 QGLLE-NNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRP-AAQTSFEDYV 397
LE ++ LV A + ++E + ++Q AK+L ++ ++ + RP S E +
Sbjct: 296 GDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFT 355
Query: 398 VNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNALINWHHPEKDKAD 446
V E+L + F P + E+ +V + PE+++ D
Sbjct: 356 VRVEHVAEMLRTIDF------QPGASGEEEEVAPDGEEGSAGPEEERPD 398
>gi|89886468 fibronectin type III and SPRY domain containing 1-like
isoform 1 [Homo sapiens]
Length = 498
Score = 115 bits (289), Expect = 1e-25
Identities = 120/497 (24%), Positives = 210/497 (42%), Gaps = 76/497 (15%)
Query: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSS 316
KE L + I L K ++++ I L+ +K + N E F+ L+ +L+E K S
Sbjct: 5 KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
Query: 317 VLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETDQSCFVQTAKQLHLRI 375
++ I + + + Q+Q+ + LEN+ L+ +A L + F + A+Q+ R+
Sbjct: 65 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
Query: 376 QKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNAL- 434
A+ S +P + +V+ S++ ++L L F PEI+ + V +N++
Sbjct: 125 TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVP-KAPEIDPVECLVADNSVT 183
Query: 435 INWHHPEKD-KADSYVLEYRKINRD------DEMSWNEIE-VCGTSKIIQDLENSSTYA- 485
+ W PE+D K D ++LE+RK N D DE W I+ + GT + L+ S Y
Sbjct: 184 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 243
Query: 486 FRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVE------- 538
FRVRA ++ S + L T +F D ++ HL L ++ VE
Sbjct: 244 FRVRACNKAVAGEYSDPVTLET---KALNFNLDN----SSSHLNLKVEDTCVEWDPTGGK 296
Query: 539 ---------SRAGFNLLLAAERIQVG-----------YYTSLDY-IIGDTGITKGKHFWA 577
G + + +R VG +T Y ++GDT I G+H+W
Sbjct: 297 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWE 356
Query: 578 FRVEPYSYLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTL-V 636
+ + VGVA G D ++ + + V
Sbjct: 357 VKAQKDCKSYSVGVAYK------------------------TLGKFDQLGKTNTSWCIHV 392
Query: 637 TIGMQKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCS 696
+Q F K +N+ + + +P IG+F D D G++ FYD + + LY + +
Sbjct: 393 NNWLQNTFAAK---HNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFT 449
Query: 697 HTLYPAFALMGSGGIQL 713
+ P F ++ GG+ L
Sbjct: 450 QPVLPGF-MVWCGGLSL 465
>gi|223718222 fibronectin type III and SPRY domain containing 1-like
isoform 3 [Homo sapiens]
Length = 530
Score = 114 bits (285), Expect = 3e-25
Identities = 119/497 (23%), Positives = 210/497 (42%), Gaps = 76/497 (15%)
Query: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSS 316
+E L + I L K ++++ I L+ +K + N E F+ L+ +L+E K S
Sbjct: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
Query: 317 VLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETDQSCFVQTAKQLHLRI 375
++ I + + + Q+Q+ + LEN+ L+ +A L + F + A+Q+ R+
Sbjct: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
Query: 376 QKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNAL- 434
A+ S +P + +V+ S++ ++L L F PEI+ + V +N++
Sbjct: 157 TMASAFRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPVP-KAPEIDPVECLVADNSVT 215
Query: 435 INWHHPEKD-KADSYVLEYRKINRD------DEMSWNEIE-VCGTSKIIQDLENSSTYA- 485
+ W PE+D K D ++LE+RK N D DE W I+ + GT + L+ S Y
Sbjct: 216 VAWRMPEEDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSKYMN 275
Query: 486 FRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRDRVE------- 538
FRVRA ++ S + L T +F D ++ HL L ++ VE
Sbjct: 276 FRVRACNKAVAGEYSDPVTLET---KALNFNLDN----SSSHLNLKVEDTCVEWDPTGGK 328
Query: 539 ---------SRAGFNLLLAAERIQVG-----------YYTSLDY-IIGDTGITKGKHFWA 577
G + + +R VG +T Y ++GDT I G+H+W
Sbjct: 329 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWE 388
Query: 578 FRVEPYSYLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTL-V 636
+ + VGVA G D ++ + + V
Sbjct: 389 VKAQKDCKSYSVGVAYK------------------------TLGKFDQLGKTNTSWCIHV 424
Query: 637 TIGMQKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCS 696
+Q F K +N+ + + +P IG+F D D G++ FYD + + LY + +
Sbjct: 425 NNWLQNTFAAK---HNNKVKALDVTVPEKIGVFCDFDGGQLSFYDANSKQLLYSFKTKFT 481
Query: 697 HTLYPAFALMGSGGIQL 713
+ P F ++ GG+ L
Sbjct: 482 QPVLPGF-MVWCGGLSL 497
>gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens]
Length = 241
Score = 110 bits (275), Expect = 5e-24
Identities = 80/277 (28%), Positives = 116/277 (41%), Gaps = 83/277 (29%)
Query: 18 AKGKVTIKNIERELICPACKELFTHPL-ILPCQHSICHKCVKELLLTLDDSFNDVGSDNS 76
+K + T+ N+E++LICP C E+FT P+ ILPCQH++C KC SD
Sbjct: 11 SKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCA---------------SDIF 55
Query: 77 NQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNF 136
S+P L P+ + R F CP C H+V L G+ GL RN
Sbjct: 56 QASNPYL--PTRGGTTMASGGR--------------FRCPSCRHEVVLDRHGVYGLQRNL 99
Query: 137 TLETIVERYRQAARAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQH 196
+E I++ Y+Q + P ++S +
Sbjct: 100 LVENIIDIYKQESTR-----------PEKKSDQP-------------------------- 122
Query: 197 EYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTL 256
MC EHE ERIN+YC C P C LCK+ G H + +V ++ ++
Sbjct: 123 --------------MCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQ 168
Query: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGE 293
K +LS I L+G +V+ IS+L K E E
Sbjct: 169 KSELSDGIAILVGSNDRVQGVISQLEDTCKTIEIGFE 205
>gi|28195390 tripartite motif-containing 42 [Homo sapiens]
Length = 723
Score = 108 bits (271), Expect = 1e-23
Identities = 97/417 (23%), Positives = 169/417 (40%), Gaps = 72/417 (17%)
Query: 26 NIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRL 85
++ L CP C L H +LPC HS+C KC+++L
Sbjct: 139 HLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQ------------------------ 174
Query: 86 PSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERY 145
K +T + CP C+ + L N+ + +RY
Sbjct: 175 ----------------KHAEVTENFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRY 218
Query: 146 RQAA--------RAATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHE 197
Q R++ I+C +C+ + + K C+ C + CN+C K H H
Sbjct: 219 MQEHGYLKWRFDRSSGPILCQVCRNR-RIAYKRCITCRLNLCNDCLKAFHS-DVAMQDHV 276
Query: 198 YVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLK 257
+V + + + + C H + RI YC + +C CK H H ++ A
Sbjct: 277 FVDTSAEEQDEKI-CIHHPSSRIIEYCRNDNKLLCTFCKFSF-HNGHDTISLIDACSERA 334
Query: 258 EKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSV 317
L I ++ + + E N+L + + E ++E F KL +L+E++ +
Sbjct: 335 ASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKII 394
Query: 318 LKAIDSSKKLRLDKFQTQMEEY-----QGLLENNGLVGYAQEVLKETDQSCFVQTAKQLH 372
++ I++ + R Q ++E+Y + E +GL+ Y++E LKET Q F+Q+AK L
Sbjct: 395 MEQIENLEVSR----QKEIEKYVYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILV 450
Query: 373 LRIQKATESLKSFRPAAQTSFE-------DYVVNTSKQTELL--GELSFFSSGIDVP 420
+I+ ++ ++RP Q D+V +S EL G SSG +P
Sbjct: 451 DQIEDGIQT--TYRPDPQLRLHSINYVPLDFVELSSAIHELFPTGPKKVRSSGDSLP 505
>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
sapiens]
Length = 496
Score = 101 bits (252), Expect = 2e-21
Identities = 120/487 (24%), Positives = 201/487 (41%), Gaps = 68/487 (13%)
Query: 257 KEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSS 316
+E L K I L K +++S I L ++ E N + +E+ F+ LF +LEE K
Sbjct: 5 REALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEELKEG 64
Query: 317 VLKAIDSSKKLRLDKFQTQMEEYQGLLENN-GLVGYAQEVLKETDQSCFVQTAKQLHLRI 375
+L I + R + Q Q+ LE++ L+ A + L+ D F Q AKQ+ +
Sbjct: 65 MLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIKDGV 124
Query: 376 QKATESLKSFRPAAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEEQSKVYNNAL- 434
A S + + +V+ +++ ++L L F P I+ +S V +N +
Sbjct: 125 TMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLPVP-SAPVIDLAESLVADNCVT 183
Query: 435 INWHHPEKD-KADSYVLEYRKINRD------DEMSWNEIE-VCGTSKIIQDLENSSTYA- 485
+ W P++D K D YVLEYR+ N + ++ W IE + T + L+ Y
Sbjct: 184 LVWRMPDEDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTGLKFDMKYMN 243
Query: 486 FRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNN-----------------EHL 528
FRV+A ++ S + L T P F F D + N + +
Sbjct: 244 FRVKACNKAVAGEFSEPVTLET---PAFMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDI 300
Query: 529 LLNLKRDRVESRAGFNL----LLAAERIQVG-----YYTSLDY-IIGDTGITKGKHFWAF 578
K + + + N + +R+ G +T+ Y ++GDT I G+H+W
Sbjct: 301 KAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEV 360
Query: 579 RVEPYSYLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTI 638
R EP S VGVA R+EQ G + S C V
Sbjct: 361 RYEPDSKAFGVGVAYRS-------------LGRFEQ-LGKTAAS--WCLH-------VNN 397
Query: 639 GMQKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHT 698
+Q F K +N+ + P+P +G+ D +G + FY+ + L+ + +
Sbjct: 398 WLQVSFTAK---HANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQP 454
Query: 699 LYPAFAL 705
L PAF +
Sbjct: 455 LLPAFTV 461
>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
sapiens]
Length = 562
Score = 97.1 bits (240), Expect = 5e-20
Identities = 81/363 (22%), Positives = 152/363 (41%), Gaps = 33/363 (9%)
Query: 33 CPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRLPSPSMDK 92
CP C LF P +LPC H++C C+++L SD S++ S L
Sbjct: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQEL------- 81
Query: 93 IDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTL--ETIVERYRQAAR 150
K SL + + CP C+ VDL G+ L + + ++E R +
Sbjct: 82 ---------KPRSLQSQIGIL-CPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQ 131
Query: 151 AATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHH-----PWGTIKAQHEYVGPTTNF 205
++CDLC +E K C C A+ C+ C + H + T+ + G +
Sbjct: 132 G---LVCDLCND--REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG 186
Query: 206 RPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDID 265
+P ++CP H E + ++CE C RPVC C + G H H S+ + + + +
Sbjct: 187 KP--ILCPVHPAEELRLFCEFCDRPVCQDCVV-GEHREHPCDFTSNVIHKHGDSVWELLK 243
Query: 266 YLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSK 325
++ +++++++ + E + T E + +EE + +LK ++ +
Sbjct: 244 GTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIR 303
Query: 326 KLRLDKFQTQMEEYQGLLENNGL-VGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKS 384
+ + Q Q + + LL + V + + +L + T + + R++K + S
Sbjct: 304 AQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYS 363
Query: 385 FRP 387
RP
Sbjct: 364 TRP 366
>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
sapiens]
Length = 580
Score = 97.1 bits (240), Expect = 5e-20
Identities = 81/363 (22%), Positives = 152/363 (41%), Gaps = 33/363 (9%)
Query: 33 CPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRLPSPSMDK 92
CP C LF P +LPC H++C C+++L SD S++ S L
Sbjct: 29 CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQEL------- 81
Query: 93 IDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTL--ETIVERYRQAAR 150
K SL + + CP C+ VDL G+ L + + ++E R +
Sbjct: 82 ---------KPRSLQSQIGIL-CPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGEGQ 131
Query: 151 AATAIMCDLCKPPPQESTKSCMDCSASYCNECFKIHH-----PWGTIKAQHEYVGPTTNF 205
++CDLC +E K C C A+ C+ C + H + T+ + G +
Sbjct: 132 G---LVCDLCND--REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKDLKGYSRIG 186
Query: 206 RPKILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDID 265
+P ++CP H E + ++CE C RPVC C + G H H S+ + + + +
Sbjct: 187 KP--ILCPVHPAEELRLFCEFCDRPVCQDCVV-GEHREHPCDFTSNVIHKHGDSVWELLK 243
Query: 266 YLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSK 325
++ +++++++ + E + T E + +EE + +LK ++ +
Sbjct: 244 GTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEHRDKLLKQLEDIR 303
Query: 326 KLRLDKFQTQMEEYQGLLENNGL-VGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKS 384
+ + Q Q + + LL + V + + +L + T + + R++K + S
Sbjct: 304 AQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYS 363
Query: 385 FRP 387
RP
Sbjct: 364 TRP 366
>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
Length = 551
Score = 95.1 bits (235), Expect = 2e-19
Identities = 84/362 (23%), Positives = 140/362 (38%), Gaps = 61/362 (16%)
Query: 28 ERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRLPS 87
E ELICP C +F P+ LPC+H+ C C+ E
Sbjct: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCIGE---------------------------- 41
Query: 88 PSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYR- 146
W ++S R CP C + GL +N L IVE++
Sbjct: 42 ------------AWAKDSGLVR-----CPECNQAYNQKP----GLEKNLKLTNIVEKFNA 80
Query: 147 -QAARAATAIMCDLCKP-PPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGPTTN 204
+ A+ C C+ PP + K C+ C A C + H + H V
Sbjct: 81 LHVEKPPAALHCVFCRRGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEADD- 139
Query: 205 FRPKILMCPEHETERINMYCELCRRPVC-HLCKLGGNHANHRVTTMSSAYKTLKEKLSKD 263
+ CP+H R+ +CE + VC + C G H H V + +++ L K
Sbjct: 140 --VRAWSCPQHNAYRL-YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQ 196
Query: 264 IDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDS 323
D L +E ++ Q+ +L + E + KEE +EKL ++L+E ++ +D
Sbjct: 197 QDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQTVEVLDK 256
Query: 324 SK-KLRLDKFQTQMEEYQGLLENNGLVGYAQEVLKETDQSCFVQTAKQLHL---RIQKAT 379
++ K + + + + E L+G Q + +T+ F++ K + + R Q T
Sbjct: 257 AQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCT 316
Query: 380 ES 381
S
Sbjct: 317 SS 318
>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
sapiens]
Length = 749
Score = 82.0 bits (201), Expect = 2e-15
Identities = 66/310 (21%), Positives = 141/310 (45%), Gaps = 20/310 (6%)
Query: 214 EHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQ 273
E E E +++C C+ P+ K+ H H V ++ A ++ K+++ K++ L + +
Sbjct: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
Query: 274 VKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQ 333
+++ + L + E N + ++ +H+ ++ E L ++ ++A+ KK +L+
Sbjct: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
Query: 334 TQMEEYQGLLENNGLVGYAQEVLKETDQSC------FVQTAKQLHLRIQKATESLKSFRP 387
Q+ L+ +E+++ ++ C F++ A + R+ K ++
Sbjct: 290 GQLVSCGENLDT------CKELMETIEEMCHEEKVDFIKDAVAMADRLGKFLKTKTDVEI 343
Query: 388 AAQTSFEDYVVNTSKQTELLGELSFFSSGIDVPEINEE--QSKVYNNALINWHHPEKDKA 445
+AQ FED ++ S +L+G ++ + P IN + S ++ + W D
Sbjct: 344 SAQPEFEDQTLDFSDVEQLMGSINTIPAP-SAPVINPQVPNSATGSSVRVCWSLYSDDTV 402
Query: 446 DSYVLEYRKINRDDEMSWNEIEVCGTSK----IIQDLENSSTYAFRVRAYKGSICSPCSR 501
+SY L YR + +D ++ E T K + +L ++ Y F V A+ + SP S
Sbjct: 403 ESYQLSYRPV-QDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSE 461
Query: 502 ELILHTPPAP 511
+ T P+P
Sbjct: 462 RAVYMTAPSP 471
Score = 47.4 bits (111), Expect = 5e-05
Identities = 77/368 (20%), Positives = 139/368 (37%), Gaps = 53/368 (14%)
Query: 359 TDQSCFVQTAKQLHLRIQKATESLKSFRPAAQTSFEDYVVNTSKQ-TELLGELSFFSSGI 417
TDQ+ F T K+ + + + T +E +V ++ E + + +
Sbjct: 419 TDQAEFTVTVKETYCSVTNLVPN---------TQYEFWVTAHNRAGPSPSSERAVYMTAP 469
Query: 418 DVPEINEEQSKVYNNA-LINWHHPEKDKADSYVLEYRKINRDDEMSWNEIEV-CGTSKII 475
P I ++ + A LI W + DSY +E + + E V T + +
Sbjct: 470 SPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESV 529
Query: 476 QDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYNNEHLLLNLKRD 535
L+ +Y VRA S S +HT + + L + C H L + D
Sbjct: 530 VQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGS--YFRLNKDTC-----HPWLTISED 582
Query: 536 -----RVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVEPYSYLVKVG 590
R E R L ++ ++T ++G+ +G H+W V+ + +VG
Sbjct: 583 GLTAVRSERRTPARELSPSDT----HFTRCVAVMGNLIPVRGHHYWEVEVDEHLDY-RVG 637
Query: 591 VASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMQKFFIPKSPT 650
VA +D R ++D G + C T + + F+ T
Sbjct: 638 VAFADV--------------RKQEDLGAN------CLSWCMRHTFASSRHKYEFLHNRTT 677
Query: 651 SSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLYPAFALMGSGG 710
P+ R+ P IGI LD + K+ F+++D + LY ++P F+L G
Sbjct: 678 ----PDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGC 733
Query: 711 IQLEEPIT 718
+++ I+
Sbjct: 734 LKVHNGIS 741
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 78.2 bits (191), Expect = 3e-14
Identities = 67/310 (21%), Positives = 140/310 (45%), Gaps = 20/310 (6%)
Query: 214 EHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQ 273
E + +I+ YC C+ P+ K+ G H +H V+T+ +A +K +L++ ++ L K +
Sbjct: 3503 ELKKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQEKSLR 3562
Query: 274 VKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQ 333
+++ +SE+ E N + ++ E++ + + + ++ + KK +++
Sbjct: 3563 IEAFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKMEFLH 3622
Query: 334 TQMEEY-QGLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFR--PAAQ 390
QM + Q + + +E D++ F+ + ++++ R+ A ES S PAA
Sbjct: 3623 EQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINERLLSAMESTASLEKMPAAF 3682
Query: 391 TSFEDYVVNTSKQTELLGELSFFSSGIDVP-----EINEEQSKVYNNALINWHHPEKDKA 445
+ FE Y ++++ ++L +++ VP E E S + W ++D
Sbjct: 3683 SLFEHYDDSSARSDQMLKQVA-------VPQPPRLEPQEPNSATSTTIAVYWSMNKEDVI 3735
Query: 446 DSYVLEYRKINRDDE-----MSWNEIEVCGTSKIIQDLENSSTYAFRVRAYKGSICSPCS 500
DS+ + + +DD+ + + V + I +DLE Y V A + CS S
Sbjct: 3736 DSFQVYCMEEPQDDQEVNELVEEYRLTVKESYCIFEDLEPDRCYQVWVMAVNFTGCSLPS 3795
Query: 501 RELILHTPPA 510
I T P+
Sbjct: 3796 ERAIFRTAPS 3805
Score = 34.7 bits (78), Expect = 0.32
Identities = 62/305 (20%), Positives = 115/305 (37%), Gaps = 46/305 (15%)
Query: 406 LLGELSFFSSGIDVPEINEEQSKV-YNNALINWHHPEKDKADSYVLEYRKINRDDEMSWN 464
L E + F + P I E V +N A I W + ++Y LEY + + +
Sbjct: 3793 LPSERAIFRTAPSTPVIRAEDCTVCWNTATIRWRPTTPEATETYTLEYCRQHSPEGEGLR 3852
Query: 465 EIEVCGTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYN 524
++ +L+ + Y F VRA S S ++ T FL + +
Sbjct: 3853 SFSGIKGLQLKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGT---RFLLLRETAHP 3909
Query: 525 NEHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLDYIIGDTGITKGKHFWAFRVEPYS 584
H+ S +G ++ ER ++ T + ++G+ + G+H+W V
Sbjct: 3910 ALHI----------SSSG-TVISFGERRRL---TEIPSVLGEELPSCGQHYWETTVTDCP 3955
Query: 585 YLVKVGVASSDKLQEWLRSPRDAVSPRYEQDSGHDSGSEDACFDSSQPFTLVTIGMQKFF 644
++G+ SS +Q A + + S + SE Q +T G+
Sbjct: 3956 -AYRLGICSSSAVQ--------AGALGQGETSWYMHCSE------PQRYTFFYSGIVS-- 3998
Query: 645 IPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVDFYDMDQMKCLYERQVDCSHTLYPAFA 704
+ V P +GI LD + ++ F + + + L+ + + ++PAFA
Sbjct: 3999 -----------DVHVTERPARVGILLDYNNQRLIFINAESEQLLFIIRHRFNEGVHPAFA 4047
Query: 705 LMGSG 709
L G
Sbjct: 4048 LEKPG 4052
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 76.6 bits (187), Expect = 7e-14
Identities = 79/321 (24%), Positives = 130/321 (40%), Gaps = 57/321 (17%)
Query: 43 PLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRLPSPSMDKIDR---INRP 99
P +LPC HS C +C+ L LP+P + + + P
Sbjct: 68 PKLLPCLHSFCQRCLPA-------------------PQRYLMLPAPMLGSAETPPPVPAP 108
Query: 100 GWKRNSLTPRTT---VFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAARAATAIM 156
G + +P T V CP C + ER I NF ++ E + +
Sbjct: 109 GSPVSGSSPFATQVGVIRCPVCSQEC--AERHI---IDNFFVKDTTEVPSSTVEKSNQV- 162
Query: 157 CDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIK----AQHEYVGP----TTNFRPK 208
C C+ E+ C++C C C + H K Q E V P T+ RP
Sbjct: 163 CTSCEDNA-EANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRP- 220
Query: 209 ILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYK-------TLKEKLS 261
+ CP H+ E++ +YCE C + C C+L H HR + A++ TL KL
Sbjct: 221 -VFCPFHKKEQLKLYCETCDKLTCRDCQL-LEHKEHRYQFIEEAFQNQKVIIDTLITKLM 278
Query: 262 KDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAI 321
+ Y+ +Q++++I E+N K+ E ++ + F + E+ ++ K ++L +
Sbjct: 279 EKTKYIKFTGNQIQNRIIEVNQNQKQVE------QDIKVAIFTLMVEINKKGK-ALLHQL 331
Query: 322 DSSKKLRLDKFQTQMEEYQGL 342
+S K K Q +E GL
Sbjct: 332 ESLAKDHRMKLMQQQQEVAGL 352
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 76.6 bits (187), Expect = 7e-14
Identities = 79/321 (24%), Positives = 130/321 (40%), Gaps = 57/321 (17%)
Query: 43 PLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRLRLPSPSMDKIDR---INRP 99
P +LPC HS C +C+ L LP+P + + + P
Sbjct: 68 PKLLPCLHSFCQRCLPA-------------------PQRYLMLPAPMLGSAETPPPVPAP 108
Query: 100 GWKRNSLTPRTT---VFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQAARAATAIM 156
G + +P T V CP C + ER I NF ++ E + +
Sbjct: 109 GSPVSGSSPFATQVGVIRCPVCSQEC--AERHI---IDNFFVKDTTEVPSSTVEKSNQV- 162
Query: 157 CDLCKPPPQESTKSCMDCSASYCNECFKIHHPWGTIK----AQHEYVGP----TTNFRPK 208
C C+ E+ C++C C C + H K Q E V P T+ RP
Sbjct: 163 CTSCEDNA-EANGFCVECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRP- 220
Query: 209 ILMCPEHETERINMYCELCRRPVCHLCKLGGNHANHRVTTMSSAYK-------TLKEKLS 261
+ CP H+ E++ +YCE C + C C+L H HR + A++ TL KL
Sbjct: 221 -VFCPFHKKEQLKLYCETCDKLTCRDCQL-LEHKEHRYQFIEEAFQNQKVIIDTLITKLM 278
Query: 262 KDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAITHFEKLFEVLEERKSSVLKAI 321
+ Y+ +Q++++I E+N K+ E ++ + F + E+ ++ K ++L +
Sbjct: 279 EKTKYIKFTGNQIQNRIIEVNQNQKQVE------QDIKVAIFTLMVEINKKGK-ALLHQL 331
Query: 322 DSSKKLRLDKFQTQMEEYQGL 342
+S K K Q +E GL
Sbjct: 332 ESLAKDHRMKLMQQQQEVAGL 352
>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
[Homo sapiens]
Length = 546
Score = 72.4 bits (176), Expect = 1e-12
Identities = 88/395 (22%), Positives = 149/395 (37%), Gaps = 98/395 (24%)
Query: 18 AKGKVTIKNIERELICPACKELFTH-----PLILPCQHSICHKCVKELLLTLDDSFNDVG 72
++G +K +E C C+++F+ P +L C H++CH C+ L L
Sbjct: 20 SRGTAVVKVLE----CGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPL---------- 65
Query: 73 SDNSNQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGL 132
CP DLG+ G+ GL
Sbjct: 66 ------------------------------------HGRAIRCPFDRQVTDLGDSGVWGL 89
Query: 133 FRNFTLETIVERYRQ-------------AARAATAIMCDLCKPPPQESTKSCMDCSASYC 179
+NF L ++ER + + I CD + ++ C C+ C
Sbjct: 90 KKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCD--EDEAHLASVYCTVCATHLC 147
Query: 180 NECFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYC--ELCRRP--VCHLC 235
+EC ++ H T+ A+H V P + + MC +H+ I C E C+ +C +C
Sbjct: 148 SECSQVTHSTKTL-AKHRRV-PLADKPHEKTMCSQHQVHAIEFVCLEEGCQTSPLMCCVC 205
Query: 236 KLGGNHANHR--------------VTTMSSAYKTLKEKLSKDIDYLIGKESQVK--SQIS 279
K G H H+ + M+ +T E++S L+G ++ QI
Sbjct: 206 KEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIV 265
Query: 280 ELNLLMKETE---CNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQM 336
E + M TE E A+ +F L E L ++ L +D+ + +L + Q
Sbjct: 266 EDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIWLRQQQ 325
Query: 337 EEYQGLL-ENNGLVGYAQEVLKETDQSCFVQTAKQ 370
E+ LL E + + ++ L++ D C V AKQ
Sbjct: 326 EDMTILLSEVSAACLHCEKTLQQDD--CRVVLAKQ 358
>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
[Homo sapiens]
Length = 569
Score = 72.4 bits (176), Expect = 1e-12
Identities = 88/395 (22%), Positives = 149/395 (37%), Gaps = 98/395 (24%)
Query: 18 AKGKVTIKNIERELICPACKELFTH-----PLILPCQHSICHKCVKELLLTLDDSFNDVG 72
++G +K +E C C+++F+ P +L C H++CH C+ L L
Sbjct: 20 SRGTAVVKVLE----CGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPL---------- 65
Query: 73 SDNSNQSSPRLRLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGL 132
CP DLG+ G+ GL
Sbjct: 66 ------------------------------------HGRAIRCPFDRQVTDLGDSGVWGL 89
Query: 133 FRNFTLETIVERYRQ-------------AARAATAIMCDLCKPPPQESTKSCMDCSASYC 179
+NF L ++ER + + I CD + ++ C C+ C
Sbjct: 90 KKNFALLELLERLQNGPIGQYGAAEESIGISGESIIRCD--EDEAHLASVYCTVCATHLC 147
Query: 180 NECFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYC--ELCRRP--VCHLC 235
+EC ++ H T+ A+H V P + + MC +H+ I C E C+ +C +C
Sbjct: 148 SECSQVTHSTKTL-AKHRRV-PLADKPHEKTMCSQHQVHAIEFVCLEEGCQTSPLMCCVC 205
Query: 236 KLGGNHANHR--------------VTTMSSAYKTLKEKLSKDIDYLIGKESQVK--SQIS 279
K G H H+ + M+ +T E++S L+G ++ QI
Sbjct: 206 KEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIV 265
Query: 280 ELNLLMKETE---CNGERAKEEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQM 336
E + M TE E A+ +F L E L ++ L +D+ + +L + Q
Sbjct: 266 EDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIWLRQQQ 325
Query: 337 EEYQGLL-ENNGLVGYAQEVLKETDQSCFVQTAKQ 370
E+ LL E + + ++ L++ D C V AKQ
Sbjct: 326 EDMTILLSEVSAACLHCEKTLQQDD--CRVVLAKQ 358
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,470,511
Number of Sequences: 37866
Number of extensions: 1319967
Number of successful extensions: 5132
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 206
Number of HSP's successfully gapped in prelim test: 151
Number of HSP's that attempted gapping in prelim test: 4334
Number of HSP's gapped (non-prelim): 857
length of query: 728
length of database: 18,247,518
effective HSP length: 110
effective length of query: 618
effective length of database: 14,082,258
effective search space: 8702835444
effective search space used: 8702835444
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.