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Search of human proteins with 62821790
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62821790 leucine zipper protein 2 [Homo sapiens]
(346 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62821790 leucine zipper protein 2 [Homo sapiens] 674 0.0
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 69 6e-12
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 63 4e-10
gi|7705415 hook homolog 1 [Homo sapiens] 59 8e-09
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 58 1e-08
gi|117968420 NUF2, NDC80 kinetochore complex component [Homo sap... 55 7e-08
gi|117968353 NUF2, NDC80 kinetochore complex component [Homo sap... 55 7e-08
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 55 7e-08
gi|71061468 centromere protein E [Homo sapiens] 54 2e-07
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 54 2e-07
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 54 3e-07
gi|21735548 centrosomal protein 2 [Homo sapiens] 54 3e-07
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens] 53 4e-07
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 53 4e-07
gi|38044112 restin isoform b [Homo sapiens] 53 5e-07
gi|4506751 restin isoform a [Homo sapiens] 53 5e-07
gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens] 53 5e-07
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 53 5e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 52 6e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 52 6e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 52 6e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 52 6e-07
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 52 6e-07
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 52 6e-07
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 52 6e-07
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 52 6e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 52 8e-07
gi|109134347 NY-REN-58 antigen [Homo sapiens] 52 8e-07
gi|109134355 NY-REN-58 antigen [Homo sapiens] 52 8e-07
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 51 2e-06
>gi|62821790 leucine zipper protein 2 [Homo sapiens]
Length = 346
Score = 674 bits (1739), Expect = 0.0
Identities = 346/346 (100%), Positives = 346/346 (100%)
Query: 1 MKFSPAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQ 60
MKFSPAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQ
Sbjct: 1 MKFSPAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQ 60
Query: 61 SLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVE 120
SLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVE
Sbjct: 61 SLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVE 120
Query: 121 RKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTD 180
RKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTD
Sbjct: 121 RKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTD 180
Query: 181 LEQKLAVAKNELEKAALDRESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPP 240
LEQKLAVAKNELEKAALDRESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPP
Sbjct: 181 LEQKLAVAKNELEKAALDRESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPP 240
Query: 241 RNIASKLPDAAAKSKPQQSASGNNESSQVESTKEGNPSTTACDSQDEGRPCSMKHKESPP 300
RNIASKLPDAAAKSKPQQSASGNNESSQVESTKEGNPSTTACDSQDEGRPCSMKHKESPP
Sbjct: 241 RNIASKLPDAAAKSKPQQSASGNNESSQVESTKEGNPSTTACDSQDEGRPCSMKHKESPP 300
Query: 301 SNATAETEPIPQKLQMPPCSECEVKKAPEKPLTSFEGMAAREEKIL 346
SNATAETEPIPQKLQMPPCSECEVKKAPEKPLTSFEGMAAREEKIL
Sbjct: 301 SNATAETEPIPQKLQMPPCSECEVKKAPEKPLTSFEGMAAREEKIL 346
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 68.9 bits (167), Expect = 6e-12
Identities = 46/191 (24%), Positives = 95/191 (49%), Gaps = 5/191 (2%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
EL ++ E + ++ + + EL + ++ + K E+ ++ L E + R
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRN 574
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
E++ ++E L+ + E K +K + N L+ +VE K+K I +LQ ENK+LK K + +K
Sbjct: 575 ELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESK 634
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKN---ELEKAALDRESQ 202
++ + K++ +L+ + ++ Q+ ++E K +N E+EKA + +
Sbjct: 635 QLNVYEIKVNKLELELESAKQKFGEITDTYQK--EIEDKKISEENLLEEVEKAKVIADEA 692
Query: 203 MKAMKETVQLC 213
+K KE + C
Sbjct: 693 VKLQKEIDKRC 703
Score = 59.3 bits (142), Expect = 5e-09
Identities = 64/288 (22%), Positives = 119/288 (41%), Gaps = 37/288 (12%)
Query: 13 LPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQ-------SLKND 65
L L+ +R +LE++ K + + + ++EL+ IKV+LQ +L+ D
Sbjct: 285 LTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEED 344
Query: 66 EQSAKTDVQKLLELGQKQREEMKSLQEA--------------LQNQLKETSEKAEKHQAT 111
Q A + +L E + Q EE + A L+ L+ ++ EK++
Sbjct: 345 LQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQ 404
Query: 112 INFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDL 171
+ L E+++KS + ++ L+ NK + EE KK+ + + L Y K
Sbjct: 405 LKILTMELQKKSSELEEMTK---------LTNNK--EVELEELKKVLGEKETLLYENKQF 453
Query: 172 LFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQLCLTSV-----FRDQPPPPL 226
A++L EQ+L EK D E Q+ A+ + Q V +
Sbjct: 454 EKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKN 513
Query: 227 SLITSNPTRMLLPPRNIASKLPDAAAKSKPQQSASGNNESSQVESTKE 274
+ +TS+ ++ L + + + D + K QQ NN+ + K+
Sbjct: 514 TELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQ 561
Score = 46.6 bits (109), Expect = 3e-05
Identities = 39/179 (21%), Positives = 80/179 (44%), Gaps = 36/179 (20%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
R+ E K ++E+ +E + ++ T S++L+ ++ + L+ + +SAK ++ +
Sbjct: 605 RKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTY 664
Query: 81 QKQREEMKSLQEAL-------------------------QNQLKETSEKAEKHQ------ 109
QK+ E+ K +E L Q+++ E EKH+
Sbjct: 665 QKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKI 724
Query: 110 -----ATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKE 163
+ + K++ + +S + L+ E +LK +LLS K I EE +K++ + KE
Sbjct: 725 IEERDSELGLYKSKEQEQSSLRASLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKE 783
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/201 (21%), Positives = 92/201 (45%), Gaps = 15/201 (7%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTD-------- 72
++D +KQ + + K+ + T+ EL+ ++ L+ K DE K D
Sbjct: 545 QEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQ-KRDEVKCKLDKSEENCNN 603
Query: 73 VQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVE-RKSKMIRDLQN 131
++K +E K EE++ +AL+ + S++ ++ +N L+ E+E K K
Sbjct: 604 LRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDT 663
Query: 132 ENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQ-QLTDLEQKLAVAKN 190
K +++K +S L EE +K + E +K++ + Q ++ ++ + K+
Sbjct: 664 YQKEIEDKKISEENL----LEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKH 719
Query: 191 ELEKAALDRESQMKAMKETVQ 211
+ +K +R+S++ K Q
Sbjct: 720 QYDKIIEERDSELGLYKSKEQ 740
Score = 32.7 bits (73), Expect = 0.49
Identities = 29/163 (17%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
Query: 60 QSLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEV 119
+ LK+ + + ++ K+ E++K + + + +L++ K ++++ I + +
Sbjct: 89 EGLKDSDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAI 148
Query: 120 -------ERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLL 172
E+ S + + ENK L + + LC + E + + K+ Y +++
Sbjct: 149 QELQFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETR 208
Query: 173 FKAQQLTDLEQKLAVAKNEL----EKAALDRESQMKAMKETVQ 211
L + +K+ A EL E + L+ ++K E +Q
Sbjct: 209 QVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQ 251
Score = 30.4 bits (67), Expect = 2.4
Identities = 40/205 (19%), Positives = 85/205 (41%), Gaps = 45/205 (21%)
Query: 21 RQDYEELE-------KQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDV 73
++DYE+++ K++ + K+ S +L Q+T ++++ D+
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQIT------------------EKENKMKDL 285
Query: 74 QKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVER----KSKMIRDL 129
LLE + + +++ + LK++ EK + +K ++R + + DL
Sbjct: 286 TFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDL 345
Query: 130 QNENKSL-------KNKLLSGNKLCGIHA---EESKKIQAQLKELRYGKKDLLFKAQQLT 179
Q K++ + ++ NK H+ E + L+EL L + Q+L
Sbjct: 346 QIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEEL------LRTEQQRLE 399
Query: 180 DLEQKLAVAKNELEKAALDRESQMK 204
E +L + EL+K + + E K
Sbjct: 400 KNEDQLKILTMELQKKSSELEEMTK 424
Score = 30.0 bits (66), Expect = 3.2
Identities = 20/82 (24%), Positives = 46/82 (56%), Gaps = 4/82 (4%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
E+ + Q ++ +ER + L +E ++ +L+ ++ ++ V+K LE+ ++++
Sbjct: 715 EKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAELLSVKKQLEIEREEK 774
Query: 85 EEMKSLQEALQN--QLKETSEK 104
E++K +EA +N LKE +K
Sbjct: 775 EKLK--REAKENTATLKEKKDK 794
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 62.8 bits (151), Expect = 4e-10
Identities = 60/203 (29%), Positives = 103/203 (50%), Gaps = 27/203 (13%)
Query: 32 KEVFKERSTILRQLTKTSRELDG-IKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSL 90
KE K ++ IL L KT +EL ++V +++ +++ K ++K E + + E+ S+
Sbjct: 878 KENQKGKAAIL-DLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSM 936
Query: 91 QEAL---QNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENK-------SLKNKL 140
QE L QN LK+ ++ ++ Q IN LK E+K K I LQ E K L+NKL
Sbjct: 937 QEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKL 996
Query: 141 ----------LSGNK----LCGIHAEESKKIQAQLKELRYGKK-DLLFKAQQLTDLEQKL 185
L+ K + + E+S++ QL+ YG++ +LL Q L +E+KL
Sbjct: 997 QQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKL 1056
Query: 186 AVAKNELEKAALDRESQMKAMKE 208
++A+ +L +Q K ++E
Sbjct: 1057 SLAQEDLISNRNQIGNQNKLIQE 1079
Score = 53.5 bits (127), Expect = 3e-07
Identities = 40/209 (19%), Positives = 97/209 (46%), Gaps = 13/209 (6%)
Query: 20 TRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLEL 79
T+ +EEL +++ E + + EL +K L + + +++K++ +K +
Sbjct: 823 TKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQK 882
Query: 80 GQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNK 139
G+ +++ + L++QL+ E K Q LK +E++ + L+ E S++ +
Sbjct: 883 GKAAILDLEKTCKELKHQLQVQMENTLKEQKE---LKKSLEKEKEASHQLKLELNSMQEQ 939
Query: 140 LLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVA-------KNEL 192
L+ + +E +++Q + EL+ + K +Q+ L+ +L +A +N+L
Sbjct: 940 LIQAQNTLKQNEKEEQQLQGNINELKQSSEQ---KKKQIEALQGELKIAVLQKTELENKL 996
Query: 193 EKAALDRESQMKAMKETVQLCLTSVFRDQ 221
++ ++ A KE + + + + Q
Sbjct: 997 QQQLTQAAQELAAEKEKISVLQNNYEKSQ 1025
Score = 52.8 bits (125), Expect = 5e-07
Identities = 54/215 (25%), Positives = 98/215 (45%), Gaps = 30/215 (13%)
Query: 17 VLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL 76
+L QDY +LE++ E + I Q T ++LD Q L++ +++T + ++
Sbjct: 311 LLKKEQDYTKLEEKHNEESVSKKNI--QATLHQKDLD-----CQQLQSRLSASETSLHRI 363
Query: 77 -LELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKS 135
+EL +K K L+ +L E K + +A L+ + E K + LQ+E
Sbjct: 364 HVELSEKGEATQK-----LKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQ 418
Query: 136 LKNKLLSGNKLCGIHAEESKKIQAQLKELR-YGKKDLLFKAQQLTDLEQKLAVAKNELEK 194
L +KLL + G + +LKE R + L+ K QQ+ DL+ KL+ + +L++
Sbjct: 419 LHSKLLETERQLG-------EAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKE 471
Query: 195 AA---------LDRESQMKAMKETVQLCLTSVFRD 220
LD+ Q ++ +Q T+ R+
Sbjct: 472 KVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLRE 506
Score = 50.4 bits (119), Expect = 2e-06
Identities = 55/227 (24%), Positives = 110/227 (48%), Gaps = 34/227 (14%)
Query: 18 LSTRQDY-EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL 76
L +Q++ +LE LKE +KE+ L Q T+ EL+G ++ L+ D K ++
Sbjct: 697 LQDKQEHCSQLESHLKE-YKEKYLSLEQKTE---ELEG---QIKKLEADSLEVKASKEQA 749
Query: 77 LELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDL------- 129
L+ Q+QR+ L L+ + E S++ E + ++ + ++++KS+ + +
Sbjct: 750 LQDLQQQRQ----LNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQ 805
Query: 130 QNENKSLKNKLLSGNKLCGI-HAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAV- 187
+ E + LK + ++ I H E + +IQ + EL+ K + +L+ ++ KL+
Sbjct: 806 EEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKV 865
Query: 188 ------AKNELEK-------AALDRESQMKAMKETVQLCLTSVFRDQ 221
+K+E EK A LD E K +K +Q+ + + ++Q
Sbjct: 866 SDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQ 912
Score = 46.2 bits (108), Expect = 4e-05
Identities = 73/324 (22%), Positives = 133/324 (41%), Gaps = 48/324 (14%)
Query: 27 LEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLL-ELGQKQRE 85
LE+QLKE + + QL KT ++ + QS + A+ D++++L ++G K +
Sbjct: 465 LEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKD-Q 523
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
++++L EAL + KE EK + + E ++ ++ LQ +N +L+ ++ +
Sbjct: 524 KIQNL-EALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTE 582
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKA 205
+E K+ Q L + +K L AQ D L + NEL SQ+
Sbjct: 583 KLKNQSESHKQAQENLHDQVQEQKAHLRAAQ---DRVLSLETSVNEL-------NSQLNE 632
Query: 206 MKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASKLPDAAAKSKPQQSASGNNE 265
KE V L + T +LL AAK+ + + +
Sbjct: 633 SKEKVS-------------QLDIQIKAKTELLLSAE---------AAKTAQRADLQNHLD 670
Query: 266 SSQ---VESTKEGNPSTTACDS-----QDEGRPCS-----MKHKESPPSNATAETEPIPQ 312
++Q + +E N TT D QD+ CS +K + + +TE +
Sbjct: 671 TAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEG 730
Query: 313 KLQMPPCSECEVKKAPEKPLTSFE 336
+++ EVK + E+ L +
Sbjct: 731 QIKKLEADSLEVKASKEQALQDLQ 754
Score = 45.4 bits (106), Expect = 7e-05
Identities = 53/234 (22%), Positives = 106/234 (45%), Gaps = 34/234 (14%)
Query: 21 RQDYEELEKQLKEVFKERSTI----LRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL 76
++ E L+ +LK +++ + +QLT+ ++EL K + L+N+ + ++ ++L
Sbjct: 972 KKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQL 1031
Query: 77 LE--LGQKQ-----REEMKSLQEAL---QNQLKETSEKAEKHQATINFLKT--------- 117
G++ R+++KS++E L Q L + I LKT
Sbjct: 1032 QSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDS 1091
Query: 118 -----EVERKSKMIRDLQNENKSLKNKLLSGNK-----LCGIHAEESKKIQAQLKELRYG 167
+++ + K ++D+Q E KSLK K L K + I + K+I +EL+
Sbjct: 1092 AKKEQQLQERCKALQDIQKE-KSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSH 1150
Query: 168 KKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQLCLTSVFRDQ 221
K + + + L D +Q L K EL+ A ++ ++ K Q+ V +++
Sbjct: 1151 KLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEE 1204
Score = 42.7 bits (99), Expect = 5e-04
Identities = 49/225 (21%), Positives = 96/225 (42%), Gaps = 36/225 (16%)
Query: 9 LLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQS 68
L+ L + QD + E+QL+E K I ++ + +EL K L ++ +
Sbjct: 1076 LIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCR 1135
Query: 69 AKTDVQKLLELGQKQREE-------MKSLQEALQNQLKETSEKAEKHQATINFLKTEVER 121
+ ++ KL E + + E +K ++ L Q E KA+ +A + + +R
Sbjct: 1136 QEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVE----QEKR 1191
Query: 122 KSKMIRD-LQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKK----DLLFKAQ 176
++++D ++ E + LK + + E+ K+ +++KE G K +
Sbjct: 1192 NQQILKDQVKKEEEELKKEFI----------EKEAKLHSEIKEKEVGMKKHEENEAKLTM 1241
Query: 177 QLTDLEQKLAVAK----------NELEKAALDRESQMKAMKETVQ 211
Q+T L + L K +ELEK D ++ ++ TVQ
Sbjct: 1242 QITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQ 1286
Score = 40.0 bits (92), Expect = 0.003
Identities = 52/240 (21%), Positives = 100/240 (41%), Gaps = 49/240 (20%)
Query: 18 LSTRQDYEELEKQLK-------EVFKERSTILRQL--------------TKTSRELDGIK 56
LS Q EELE Q+K EV + L+ L T+ S++L+ K
Sbjct: 719 LSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEK 778
Query: 57 VNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQ--------------EALQNQLKETS 102
+ S + D Q ++ + + KQ EE + L+ E L N+++ T
Sbjct: 779 EIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTV 838
Query: 103 EKAEK----HQATINFLKTEVERKSKMIRDLQN-------ENKSLKNKLLSGNKLCGIHA 151
+ +K +A + L T ++ SK+ L+N EN+ K +L K C
Sbjct: 839 TELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTC---K 895
Query: 152 EESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQ 211
E ++Q Q++ +K+L ++ + +L + N +++ + ++ +K ++ Q
Sbjct: 896 ELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQ 955
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 58.5 bits (140), Expect = 8e-09
Identities = 58/213 (27%), Positives = 107/213 (50%), Gaps = 21/213 (9%)
Query: 23 DYEELEKQLKEVFKERSTILRQ---LTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLL-- 77
+ + LE++ + + KE+ ++ Q L +T+ EL +V L + SA + L
Sbjct: 398 EMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAE 457
Query: 78 -------ELGQKQREEMKSL---QEALQNQ-LKETSEKAEKHQATINFLKTEVERKSKMI 126
E+ + + E K L QE +N+ ++E E+ E+ +N L+TE + I
Sbjct: 458 IMPVEYREVFIRLQHENKMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERI 517
Query: 127 RDLQNENKSLKNKLL-SGNKLCGIHAEESK-KIQAQLKELRYGKKDLLFKAQQLTDLEQK 184
R+LQ + + L+ L G+K G + + K K++A +++L ++L K + + DL+
Sbjct: 518 RELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPD 577
Query: 185 L--AVAK-NELEKAALDRESQMKAMKETVQLCL 214
+ V K NELE A ++ MKAM+E ++ L
Sbjct: 578 INQNVQKINELEAALQKKDEDMKAMEERYKMYL 610
Score = 37.4 bits (85), Expect = 0.020
Identities = 39/139 (28%), Positives = 65/139 (46%), Gaps = 25/139 (17%)
Query: 21 RQDYEELEKQLKEVFK----ERSTILRQ--------LTKTSRELDGIKVNLQSLKNDEQS 68
+Q E+L+K L+E E S+ L+Q LT+ EL + ++ L+ D
Sbjct: 521 QQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPD--- 577
Query: 69 AKTDVQKLLELG---QKQREEMKSLQ-------EALQNQLKETSEKAEKHQATINFLKTE 118
+VQK+ EL QK+ E+MK+++ E +N +K K A I L+ +
Sbjct: 578 INQNVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQ 637
Query: 119 VERKSKMIRDLQNENKSLK 137
+ K + I L++E K K
Sbjct: 638 LAEKERRIEILESECKVAK 656
Score = 34.3 bits (77), Expect = 0.17
Identities = 44/195 (22%), Positives = 80/195 (41%), Gaps = 20/195 (10%)
Query: 26 ELEKQLKEVFKERSTIL---RQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQK 82
ELE+QLK +E L +L + ELD LQ KN S + + L+
Sbjct: 175 ELEQQLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDG 234
Query: 83 QREEMKSLQEA----LQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKN 138
++ ++ Q QL++ E+ + +A + + E K + + Q+ N L +
Sbjct: 235 SFDDPNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTS 294
Query: 139 KLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALD 198
AEE++ ++ ++ LR D K + ++ ++ N+L K
Sbjct: 295 L-----------AEETRALKDEIDVLR-ATSDKANKLESTVEIYRQKLQDLNDLRKQVKT 342
Query: 199 -RESQMKAMKETVQL 212
+E+ M M TV L
Sbjct: 343 LQETNMMYMHNTVSL 357
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 58.2 bits (139), Expect = 1e-08
Identities = 49/191 (25%), Positives = 95/191 (49%), Gaps = 14/191 (7%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
RQ +E LE + +E+ + RS I +Q+T EL K + E++A +++K L
Sbjct: 371 RQMHETLEMKEEEIAQLRSRI-KQMTTQGEELREQK------EKSERAAFEELEKALSTA 423
Query: 81 QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKL 140
QK E + L+ + Q+K + +E+ + ++ + V+++ + +E + K +
Sbjct: 424 QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQK 483
Query: 141 LSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQ-------QLTDLEQKLAVAKNELE 193
L +L E +KK+Q + +E + K L K+Q Q + ++ LA+ + EL+
Sbjct: 484 LHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQ 543
Query: 194 KAALDRESQMK 204
K A+ ES+ K
Sbjct: 544 KKAILTESENK 554
Score = 50.4 bits (119), Expect = 2e-06
Identities = 41/201 (20%), Positives = 94/201 (46%), Gaps = 18/201 (8%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
ELE QL+++ +E++T+ + + +L+ + ++S+K D +S T+ + L + G Q++
Sbjct: 1273 ELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQ 1332
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERK----SKMIRDLQNENKSLKNKLL 141
+ + KE SE + +K E++ K S + + L + N L+N +
Sbjct: 1333 AASEKESCITQLKKELSENIN----AVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS 1388
Query: 142 SGNKLCGI------HAEESKKIQAQLKELRYG----KKDLLFKAQQLTDLEQKLAVAKNE 191
K I + EE ++ Q+++L + K+ + +Q+ D K + K +
Sbjct: 1389 LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1448
Query: 192 LEKAALDRESQMKAMKETVQL 212
+ ++ +K ++ ++L
Sbjct: 1449 AQSRFTQHQNTVKELQIQLEL 1469
Score = 47.0 bits (110), Expect = 3e-05
Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 46/234 (19%)
Query: 25 EELEKQ---LKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL-LELG 80
EE+ K+ LKE ++ T L +L + +L ++ SL DE K ++KL ++L
Sbjct: 1088 EEMNKEITWLKEEGVKQDTTLNELQE---QLKQKSAHVNSLAQDETKLKAHLEKLEVDLN 1144
Query: 81 ---------QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQN 131
Q+Q E+K L E + ++ E + K + LK+ E+ +K + D
Sbjct: 1145 KSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSL 1204
Query: 132 ENKSLKNKL----------------LSGNKLCGIHAEESKKIQAQLKELRYG----KKDL 171
E K L +L N+L I + ++ I +++ ++ K+ L
Sbjct: 1205 EFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1264
Query: 172 LFKA----------QQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQLCLT 215
L K +QLT+ + L ++ + ++E+Q+K+MK ++ +T
Sbjct: 1265 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVT 1318
Score = 43.5 bits (101), Expect = 3e-04
Identities = 48/197 (24%), Positives = 87/197 (44%), Gaps = 25/197 (12%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSL----KNDEQSAKTDVQKLLE 78
+ E L +L EV K R + +L+ + D +K L++ KN Q + K E
Sbjct: 685 ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHE 744
Query: 79 LG-QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLK 137
+ Q+ + +K L+ LKE + ++HQA + L+ +++R + E +
Sbjct: 745 VSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRS-------EGELQQAS 797
Query: 138 NKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLE-QKLAVAKN--ELEK 194
KL E++K + QL +L+ Q+L DLE +++ + K E+E
Sbjct: 798 AKLDVFQSYQSATHEQTKAYEEQLAQLQ----------QKLLDLETERILLTKQVAEVEA 847
Query: 195 AALDRESQMKAMKETVQ 211
D +++ A K VQ
Sbjct: 848 QKKDVCTELDAHKIQVQ 864
Score = 43.5 bits (101), Expect = 3e-04
Identities = 44/192 (22%), Positives = 84/192 (43%), Gaps = 15/192 (7%)
Query: 24 YEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQ 83
YEE QL++ + T LTK E++ K + + + + K VQ L++ +KQ
Sbjct: 817 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQK---KDVCTELDAHKIQVQDLMQQLEKQ 873
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSG 143
EM+ ++L + E K Q + E E +R+ Q + + + LS
Sbjct: 874 NSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSA 933
Query: 144 NKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
E+S I + E ++ ++ +++ ++QK + L+K LD+E+++
Sbjct: 934 K-------EDSIHILNEEYETKFKNQE-----KKMEKVKQKAKEMQETLKKKLLDQEAKL 981
Query: 204 KAMKETVQLCLT 215
K E L L+
Sbjct: 982 KKELENTALELS 993
Score = 42.7 bits (99), Expect = 5e-04
Identities = 54/238 (22%), Positives = 103/238 (43%), Gaps = 35/238 (14%)
Query: 27 LEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREE 86
LE +LK + +T+ + E++ + + LKN Q + ++L++ + +
Sbjct: 1516 LETELKSQTARIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQ----KLQH 1568
Query: 87 MKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKL 146
+ L E N++KE EK + + +K E+E K K +L++ N S+K+K
Sbjct: 1569 FQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK---ELEHVNLSVKSK------- 1618
Query: 147 CGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAM 206
EE K ++ +L+ K A+ EQK+A K +L ++E Q K
Sbjct: 1619 ----EEELKALEDRLESESAAK-----LAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKG 1669
Query: 207 KETVQLCLTSVFRDQP------PPPLSLITSNPTRMLLPPR---NIASKLPDAAAKSK 255
E+ L + +++ L + S+ + L+ PR N+A+ A S+
Sbjct: 1670 TESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQ 1727
Score = 38.1 bits (87), Expect = 0.012
Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 28/210 (13%)
Query: 27 LEKQLKEVFKERSTILRQLT------KTSRELDGIKVNLQSLKNDEQSAKTD----VQKL 76
++++LKE E S++ +QLT + S L + + SL+ K + VQ L
Sbjct: 1358 MKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDL 1417
Query: 77 -LELGQKQREEMKSLQEA--LQNQLKETSEKAE----KHQATINFLKTEVERKSKMIRDL 129
++ +E++ +L++ N+ E +KA+ +HQ T+ L+ ++E KSK +
Sbjct: 1418 SFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEK 1477
Query: 130 QNENKSLKNKLLSGNK----LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKL 185
+ LK +L NK L G ++ K++ + L + +L + ++ +LE +
Sbjct: 1478 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNL---ETELKSQTARIMELEDHI 1534
Query: 186 AVAKNELE--KAALDRESQMKAM--KETVQ 211
E+E L +Q K + KE VQ
Sbjct: 1535 TQKTIEIESLNEVLKNYNQQKDIEHKELVQ 1564
Score = 33.9 bits (76), Expect = 0.22
Identities = 34/160 (21%), Positives = 72/160 (45%), Gaps = 7/160 (4%)
Query: 50 RELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQ 109
+ L+ ++ ++ +N + K +Q E E ++LQE L +L+E + + H
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHM 338
Query: 110 ATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKK 169
A L T++ +I L+ + K +++ K E K + ++ +LR K
Sbjct: 339 AEKTKLITQLRDAKNLIEQLEQD----KGMVIAETKRQMHETLEMK--EEEIAQLRSRIK 392
Query: 170 DLLFKAQQLTDLEQKL-AVAKNELEKAALDRESQMKAMKE 208
+ + ++L + ++K A ELEKA + +A ++
Sbjct: 393 QMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRK 432
Score = 33.5 bits (75), Expect = 0.29
Identities = 42/188 (22%), Positives = 76/188 (40%), Gaps = 19/188 (10%)
Query: 28 EKQLKEVFKERSTILR-QLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREE 86
EK+L + +E I QL + +E+ +K + +++ ++ L E G KQ
Sbjct: 1048 EKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTT 1107
Query: 87 MKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKL 146
+ LQE QLK+ S LK +E+ + EN L+ +L+ L
Sbjct: 1108 LNELQE----QLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKML 1163
Query: 147 CGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAM 206
AEE K+ ++L K + + Q L + + K+ D+ + K +
Sbjct: 1164 ----AEEDKRKVSELTS----------KLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKL 1209
Query: 207 KETVQLCL 214
E + + L
Sbjct: 1210 SEELAIQL 1217
Score = 30.8 bits (68), Expect = 1.9
Identities = 35/162 (21%), Positives = 72/162 (44%), Gaps = 19/162 (11%)
Query: 27 LEKQLKEVFKERSTILRQLTKT---SRELDGIKVNLQSLKNDEQSAKTDVQKLL--ELGQ 81
L+K L+ + KE L L K RE + IK + L+ S + + +L Q
Sbjct: 1949 LQKDLRMLRKEHQQELEILKKEYDQERE-EKIKQEQEDLELKHNSTLKQLMREFNTQLAQ 2007
Query: 82 KQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLL 141
K++E +++E + + +E E HQ E +++++ + ++ LK
Sbjct: 2008 KEQELEMTIKETINKAQEVEAELLESHQ----------EETNQLLKKIAEKDDDLKRTAK 2057
Query: 142 SGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQ 183
++ EE + A++++L+ ++L K QQ + E+
Sbjct: 2058 RYEEILDAREEE---MTAKVRDLQTQLEELQKKYQQKLEQEE 2096
Score = 28.9 bits (63), Expect = 7.1
Identities = 33/150 (22%), Positives = 70/150 (46%), Gaps = 16/150 (10%)
Query: 71 TDVQKLLE-LGQKQRE------EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKS 123
T+ +KLL+ +GQ++ E EM+ + +L+ K + Q+ I L+ E+E K+
Sbjct: 1746 TEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKN 1805
Query: 124 K---MIRDLQNENKSLKNKLLSGNKLCGIHAE-----ESKKIQAQLKELRYGKKD-LLFK 174
K +I E + KN + + L + + + K++ Q+ E + + D L +
Sbjct: 1806 KKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVR 1865
Query: 175 AQQLTDLEQKLAVAKNELEKAALDRESQMK 204
+++ +E + +K E +A + + K
Sbjct: 1866 QKEVHRVEMEELTSKYEKLQALQQMDGRNK 1895
>gi|117968420 NUF2, NDC80 kinetochore complex component [Homo
sapiens]
Length = 464
Score = 55.5 bits (132), Expect = 7e-08
Identities = 47/197 (23%), Positives = 104/197 (52%), Gaps = 22/197 (11%)
Query: 25 EELEKQLKEVFKERSTILRQ--------LTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL 76
+EL++ L + F +++ +L++ +++ ++ L+ +K+++ SLK ++S KT +
Sbjct: 188 QELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESLKTKIVDS 247
Query: 77 LELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFL---KTEVERKSKMIRDLQNEN 133
E + +E+MK + L+N +E EK E + +++ L + EV+ K I+DL +
Sbjct: 248 PEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNR 307
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE 193
+ L + L L ++ + +++LK+L+ ++ FK + ++KLA A+ ++
Sbjct: 308 EKLASILKESLNL----EDQIESDESELKKLK--TEENSFKRLMIVK-KEKLATAQFKIN 360
Query: 194 KAALDRESQMKAMKETV 210
K + +K K TV
Sbjct: 361 K----KHEDVKQYKRTV 373
>gi|117968353 NUF2, NDC80 kinetochore complex component [Homo
sapiens]
Length = 464
Score = 55.5 bits (132), Expect = 7e-08
Identities = 47/197 (23%), Positives = 104/197 (52%), Gaps = 22/197 (11%)
Query: 25 EELEKQLKEVFKERSTILRQ--------LTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL 76
+EL++ L + F +++ +L++ +++ ++ L+ +K+++ SLK ++S KT +
Sbjct: 188 QELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLSVVSLKEIQESLKTKIVDS 247
Query: 77 LELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFL---KTEVERKSKMIRDLQNEN 133
E + +E+MK + L+N +E EK E + +++ L + EV+ K I+DL +
Sbjct: 248 PEKLKNYKEKMKDTVQKLKNARQEVVEKYEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNR 307
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE 193
+ L + L L ++ + +++LK+L+ ++ FK + ++KLA A+ ++
Sbjct: 308 EKLASILKESLNL----EDQIESDESELKKLK--TEENSFKRLMIVK-KEKLATAQFKIN 360
Query: 194 KAALDRESQMKAMKETV 210
K + +K K TV
Sbjct: 361 K----KHEDVKQYKRTV 373
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 55.5 bits (132), Expect = 7e-08
Identities = 58/238 (24%), Positives = 110/238 (46%), Gaps = 34/238 (14%)
Query: 7 HYLLPLLPALVL--STRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKN 64
H+L L + VL + R + E+L+ Q+ +E + + RQL EL L+
Sbjct: 1563 HHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEEL-------HLLQG 1615
Query: 65 DEQSAKTDVQKLLELGQKQ-------REEMKSLQEALQNQLKETSEKAEKHQATINFLKT 117
AK D+Q+ L LG+ + E+KSL E L Q E + + + + + +K
Sbjct: 1616 SMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQ 1675
Query: 118 EVERKSK----MIRDLQNENKSLKNKL----LSGNKLCGIHAEESKKIQAQLKELRYGKK 169
E+E++ + ++R + LKN L L ++L G+ + +++ EL +
Sbjct: 1676 EIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRV----SELEKTQV 1731
Query: 170 DLLFKAQQLTDLEQKLAVAKNELE--KAALDRE----SQMKAMKETVQLCLTSVFRDQ 221
+L + +L +L+Q K E+E K L+R+ +M A +Q C+ + +++
Sbjct: 1732 AVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEK 1789
Score = 50.1 bits (118), Expect = 3e-06
Identities = 46/220 (20%), Positives = 115/220 (52%), Gaps = 35/220 (15%)
Query: 17 VLSTRQDYEELEK--QLKEV--------FKERSTILRQLTKTSRELDGIKVNLQSLKNDE 66
+L +++++LE+ QLK++ +K+ S L+ + K +E +++ ++ K +
Sbjct: 467 ILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEI 526
Query: 67 QSAKTDVQKL------LELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVE 120
+ +++ L L+ + MK+ + + QL +++ ++ ++ ++ + + +
Sbjct: 527 AGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIA 586
Query: 121 RKSKMIRDLQNE--------NKSLKNKL---LSG-NKLCGIHAEESKKIQAQLKELRYGK 168
++++ I+DL+ + N++LK L +SG + G ++ + Q + ++LR K
Sbjct: 587 KETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEK 646
Query: 169 KDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
+ LL Q+LT++EQ+ +++LE A+D E+ K + E
Sbjct: 647 ETLL---QRLTEVEQE----RDQLEIVAMDAENMRKELAE 679
Score = 46.2 bits (108), Expect = 4e-05
Identities = 48/181 (26%), Positives = 87/181 (48%), Gaps = 11/181 (6%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
EEL Q E+ + S QLT +E++ + NLQ + KT+++ +L++ Q +
Sbjct: 1650 EELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLEN 1709
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
E++ L+ ++ E EK Q + K E+E ++ + + E + K L
Sbjct: 1710 HELQGLKLQHDQRVSE----LEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDK 1765
Query: 145 KLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDL-EQKLAVAKNELEKAALDRESQM 203
+ ES+ +Q+ ++ L K+DL Q+ D+ E+KLA K L AA + S+M
Sbjct: 1766 REIERMTAESRALQSCVECLSKEKEDL----QEKCDIWEKKLAQTKRVL--AAAEENSKM 1819
Query: 204 K 204
+
Sbjct: 1820 E 1820
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/183 (22%), Positives = 85/183 (46%), Gaps = 25/183 (13%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
+ + + +++ E+ T+L++LT+ +E D +++ +N R+
Sbjct: 634 QAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAEN------------------MRK 675
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
E+ L+ ALQ Q E + ++ Q ++ + E+E + +RD E LK +L K
Sbjct: 676 ELAELESALQEQ-HEVNASLQQTQGDLSAYEAELEARLN-LRDA--EANQLKEEL---EK 728
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKA 205
+ + E +QA+L++ R K+ L KAQ + EQ+ + +L+ D +
Sbjct: 729 VTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQ 788
Query: 206 MKE 208
+K+
Sbjct: 789 LKD 791
Score = 39.3 bits (90), Expect = 0.005
Identities = 50/204 (24%), Positives = 92/204 (45%), Gaps = 28/204 (13%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
E LEK L + ++ S +QL + S EL ++ S++ D + + L +K
Sbjct: 2014 ESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRN---QFLTERKKAE 2070
Query: 85 EEMKSLQEALQ--------NQLKETSEKA--EKHQATINFLKTE----VERKSKMIRDLQ 130
+++ SL+EAL+ N L++ E + +K ATI + + R K + +Q
Sbjct: 2071 KQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQ 2130
Query: 131 NENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKN 190
E LK ++ + L +I ++ L+ KD + L +L Q L
Sbjct: 2131 YEYTELKKQMANQKDL----ERRQMEISDAMRTLKSEVKDEI--RTSLKNLNQFLPELPA 2184
Query: 191 ELEKAALDR----ESQMKAMKETV 210
+LE A L+R E +++++KE +
Sbjct: 2185 DLE-AILERNENLEGELESLKENL 2207
Score = 38.5 bits (88), Expect = 0.009
Identities = 38/201 (18%), Positives = 86/201 (42%), Gaps = 13/201 (6%)
Query: 17 VLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVN---LQSLKNDEQSAKTDV 73
VL + + E L++ ++ E + L + RE++ + LQS K D+
Sbjct: 1733 VLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDL 1792
Query: 74 QKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
Q+ ++ +K+ + K + A + K EK + + L+ E+++ ++ L N+
Sbjct: 1793 QEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDI 1852
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQ-------QLTDLEQKLA 186
+++ +L + EE +Q L K+DLL + + T L++ ++
Sbjct: 1853 SAMQQQLQEKREAVNSLQEELANVQ---DHLNLAKQDLLHTTKHQDVLLSEQTRLQKDIS 1909
Query: 187 VAKNELEKAALDRESQMKAMK 207
N E + E++ + ++
Sbjct: 1910 EWANRFEDCQKEEETKQQQLQ 1930
Score = 37.7 bits (86), Expect = 0.015
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 115 LKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQA--QLKELRYGKKDLL 172
L T++E K K I Q L +++ + EE K+++ QLK++ KDLL
Sbjct: 435 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLL 494
Query: 173 FKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETV 210
+K L +L + N+L + ALD E QM+ K+ +
Sbjct: 495 YK-----QLSGRLQLV-NKLRQEALDLELQMEKQKQEI 526
Score = 37.7 bits (86), Expect = 0.015
Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 28/138 (20%)
Query: 81 QKQREEMKSLQEALQNQLKETSEKAEKH-QATINFLKTEVERKSKMIRDLQNENKSLKNK 139
+K +EEM QE L +E + E+ +A +NF K + E + I+ ++NE L+
Sbjct: 866 RKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEAR---IQQMENEIHYLQEN 922
Query: 140 LLSGNKLCGIHA-------EESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNEL 192
L S ++ G+ EE ++I AQL+EL + ++KL AK++
Sbjct: 923 LKSMEEIQGLTDLQLQEADEEKERILAQLREL---------------EKKKKLEDAKSQE 967
Query: 193 EKAALDRESQMKAMKETV 210
+ LD+E +K +K+ V
Sbjct: 968 QVFGLDKE--LKKLKKAV 983
Score = 37.4 bits (85), Expect = 0.020
Identities = 46/237 (19%), Positives = 95/237 (40%), Gaps = 42/237 (17%)
Query: 18 LSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQ---SAKTDVQ 74
LS D +++QL+E + +++ +L L+ K +L + S +T +Q
Sbjct: 1846 LSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQ 1905
Query: 75 KLL-------ELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERK----- 122
K + E QK+ E + + LQN+++E K + + L+ E E +
Sbjct: 1906 KDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLE 1965
Query: 123 -------------SKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKK 169
K + D +++ + +K+L+ + EE + ++ K L K+
Sbjct: 1966 TSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKR 2025
Query: 170 DLLFKAQQLTDLEQKLAVAKNELEKAALD--------------RESQMKAMKETVQL 212
L + QQL + +L + E + D E Q+ ++KE +++
Sbjct: 2026 QLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKI 2082
Score = 32.3 bits (72), Expect = 0.64
Identities = 31/169 (18%), Positives = 71/169 (42%), Gaps = 11/169 (6%)
Query: 54 GIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQE-----------ALQNQLKETS 102
G + L + Q ++ + ++L K+ EE+K L+E AL+ L+
Sbjct: 559 GKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVI 618
Query: 103 EKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLK 162
+++ TI T+ + + + +RD + ++ I A +++ ++ +L
Sbjct: 619 SGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELA 678
Query: 163 ELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQ 211
EL ++ L + L+ + ELE R+++ +KE ++
Sbjct: 679 ELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELE 727
Score = 31.2 bits (69), Expect = 1.4
Identities = 52/231 (22%), Positives = 98/231 (42%), Gaps = 48/231 (20%)
Query: 3 FSPAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSL 62
F+ Y++ A+ + + E+L + + + + QL +++ + L L
Sbjct: 398 FATESYIIDSAQAVQIKKMEPDEQLRNDHMNL-RGHTPLDTQLEDKEKKISAAQTRLSEL 456
Query: 63 KNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSE------------------- 103
++ + A+ Q++L + EE K L+EA+ QLK+ SE
Sbjct: 457 HDEIEKAE---QQIL----RATEEFKQLEEAI--QLKKISEAGKDLLYKQLSGRLQLVNK 507
Query: 104 ---KAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQ-- 158
+A + + K E+ K K I+DLQ SL +K K + A++S K Q
Sbjct: 508 LRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSK---DPKHSHMKAQKSGKEQQL 564
Query: 159 ----AQLKELRYGKKDLLFK----AQQLTDLEQKLA---VAKNELEKAALD 198
Q ++L ++L + +++ DLE++L +A NE K L+
Sbjct: 565 DIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLE 615
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 54.3 bits (129), Expect = 2e-07
Identities = 48/209 (22%), Positives = 101/209 (48%), Gaps = 20/209 (9%)
Query: 20 TRQDYEELEK--QLKEVFKERSTILRQLTKTSREL-DGIKVNLQSLKNDEQSAKTDVQKL 76
TR+ E L + QLKE + R + L+ + + + + ++ L+ +K Q K D+++L
Sbjct: 879 TREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQE-KDDLKQL 937
Query: 77 LELGQKQREEMKS-------LQEALQNQLKETSEKAEKHQATINFLKT----EVERKSKM 125
E Q +R+++KS + Q QL+ E ++HQ TIN LK+ EV R M
Sbjct: 938 QESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHM 997
Query: 126 IRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKL 185
+ + K++ +K + A+ ++ + A +K+ +++ + +++ L Q+
Sbjct: 998 EENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKD-----NEIIEQQRKIFSLIQEK 1052
Query: 186 AVAKNELEKAALDRESQMKAMKETVQLCL 214
+ LE ++E +KE +++ +
Sbjct: 1053 NELQQMLESVIAEKEQLKTDLKENIEMTI 1081
Score = 49.3 bits (116), Expect = 5e-06
Identities = 58/225 (25%), Positives = 106/225 (47%), Gaps = 35/225 (15%)
Query: 17 VLSTRQDYEELEKQLKEVFKERSTILRQL-TKTSRELDGIKVNLQSLKNDEQSAKTDVQK 75
V T++ E+E LKE F+ + L + T+ R + NL+ +++ + + D++
Sbjct: 1636 VNETQEKMCEIE-HLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKE-RDDLRS 1693
Query: 76 LLELGQKQREEMK-SLQEAL------QNQLKETSEKAEKHQATINFLKTEVERK----SK 124
+ E + +R+++K +L+E + Q +LK ++HQ TI+ L+ V K S
Sbjct: 1694 VEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISN 1753
Query: 125 MIRDLQNENKSLKNKLL------------------SGNKLCGIHAEESKKIQAQLKELRY 166
M +DL++ N +LK + L + +KL GI +E++ K+ K+L
Sbjct: 1754 MQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLEN 1813
Query: 167 GKKDLLFKAQQLTDLEQKLAVAK---NELEKAALDRESQMKAMKE 208
L K Q+L E +L K NE +K + E K +K+
Sbjct: 1814 SNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKD 1858
Score = 47.8 bits (112), Expect = 1e-05
Identities = 52/209 (24%), Positives = 107/209 (51%), Gaps = 29/209 (13%)
Query: 17 VLSTRQDYEELEKQLKEVFKERSTILRQLTKTSREL-DGIKVNLQSLKNDEQSAKTDVQK 75
V T++ E+E QLK+ K++S L +L + L + NL+ +K+ + ++++
Sbjct: 1839 VNETQKKVSEME-QLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKS-VMKERDNLRR 1896
Query: 76 LLELGQKQREEMK-SLQEA------LQNQLKETSEKAEKHQATINFLKTEVERKSKMIRD 128
+ E + +R+++K SLQE +Q +LK +++H+ T++ L+ ++ K+ I D
Sbjct: 1897 VEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISD 1956
Query: 129 LQNENKSLKNKLLSGNKLCGIHAEESKKIQ-AQLKELRY--GKKDLLFKAQQLTDLEQ-- 183
+Q + K++L KKIQ Q KEL+ K+D+ +++ ++EQ
Sbjct: 1957 IQKDLDKSKDEL-------------QKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLK 2003
Query: 184 KLAVAKN-ELEKAALDRESQMKAMKETVQ 211
K A+N ++ +D K + E+++
Sbjct: 2004 KQFEAQNLSMQSVRMDNFQLTKKLHESLE 2032
Score = 47.4 bits (111), Expect = 2e-05
Identities = 50/224 (22%), Positives = 96/224 (42%), Gaps = 40/224 (17%)
Query: 2 KFSPAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQS 61
+F P L + +L + +E ++K V KE+ + R E D +K N++
Sbjct: 1408 QFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKE 1467
Query: 62 LKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVER 121
+ V K LE EE+K L+ Q + TIN L+ +
Sbjct: 1468 I----------VAKHLE----TEEELKVAHCCLKEQ-----------EETINELRVNLSE 1502
Query: 122 KSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESK-------KIQAQLKELRYGKKDLLFK 174
K I +Q + +++ +KL NK+ I+ +E + ++Q ++ EL+ K+ K
Sbjct: 1503 KETEISTIQKQLEAINDKL--QNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAK 1560
Query: 175 AQQLTDLEQKLAVAKNELEKA------ALDRESQMKAMKETVQL 212
L +E K+ N L+++ + + +MK ++E +Q+
Sbjct: 1561 DSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQI 1604
Score = 45.4 bits (106), Expect = 7e-05
Identities = 41/193 (21%), Positives = 97/193 (50%), Gaps = 27/193 (13%)
Query: 25 EELEKQLKEVF-KERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQ-- 81
++L+ +++E++ KE ++Q+++ +++ +K + K + + ++ K+LEL
Sbjct: 1519 DKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRL 1578
Query: 82 -----------KQREEMKSLQEALQ---NQLKETSEK-----AEKHQATINFLK-TEVER 121
K++EEMK +QEALQ +QLKE +++ E + FLK T V
Sbjct: 1579 QESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNE 1638
Query: 122 KSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDL 181
+ + ++++ + + + L+ + + ++ + L+E+R K+ L +
Sbjct: 1639 TQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKE----RDDLRSV 1694
Query: 182 EQKLAVAKNELEK 194
E+ L V +++L++
Sbjct: 1695 EETLKVERDQLKE 1707
Score = 42.7 bits (99), Expect = 5e-04
Identities = 47/205 (22%), Positives = 105/205 (51%), Gaps = 36/205 (17%)
Query: 25 EELEKQLK---EVFKERSTILRQLTK--TSRELDGIKVNL----QSLKNDEQSAKT--DV 73
++LE +L E+ +E+ +++L + S++L+ IK++L +S+++ +Q +T D
Sbjct: 571 QDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDA 630
Query: 74 QKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
+ + +++ ++S L+ ++KE + ++ + I ++++E K KM DL+ E
Sbjct: 631 ETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKEL 690
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGK--KDLLFKAQ---QLTDLEQKL--A 186
+S N++ +L L GK KDLL + ++TDL+++L
Sbjct: 691 QSAFNEI------------------TKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKE 732
Query: 187 VAKNELEKAALDRESQMKAMKETVQ 211
V +NE + + S++K++ V+
Sbjct: 733 VEENEALREEVILLSELKSLPSEVE 757
Score = 42.4 bits (98), Expect = 6e-04
Identities = 39/195 (20%), Positives = 91/195 (46%), Gaps = 12/195 (6%)
Query: 18 LSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLL 77
L+ Q E +++K V KER + R E D +K +LQ K + ++Q+ L
Sbjct: 1871 LNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETK----ARDLEIQQEL 1926
Query: 78 ELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLK 137
+ + +E K + L+ ++ E + + Q ++ K E+++K + ++ + + +K
Sbjct: 1927 KTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVK 1986
Query: 138 NKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAAL 197
+ +K + K+ +AQ ++ + D L +KL + E+ A
Sbjct: 1987 EDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNF-------QLTKKLHESLEEIRIVAK 2039
Query: 198 DRESQMKAMKETVQL 212
+R+ +++ +KE++++
Sbjct: 2040 ERD-ELRRIKESLKM 2053
Score = 42.0 bits (97), Expect = 8e-04
Identities = 43/229 (18%), Positives = 99/229 (43%), Gaps = 38/229 (16%)
Query: 18 LSTRQDYEELEKQLKEVFKERSTILRQLTKTS---RELDGIKVNLQSLKNDEQSAKTDVQ 74
+ +QD E Q + + I+ Q K +E + ++ L+S+ +++ KTD++
Sbjct: 1015 IDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLK 1074
Query: 75 KLLELGQKQREEMKSLQEALQNQ-------------------------------LKETSE 103
+ +E+ + +EE++ L + L+ Q LKE S+
Sbjct: 1075 ENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQ 1134
Query: 104 KAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKE 163
+ ++ Q + ++ E+ K I +++N LKNK L+ + E ++K+ +E
Sbjct: 1135 QLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEE 1194
Query: 164 LRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQL 212
+ K + + + L +L++ ++ L + E+ KE +++
Sbjct: 1195 V----KSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKI 1239
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/182 (22%), Positives = 85/182 (46%), Gaps = 21/182 (11%)
Query: 19 STRQDYE-------ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKT 71
ST Q+++ + E++ K V +E + +++ S+E +L +LK +
Sbjct: 814 STDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQ 873
Query: 72 DVQKLLELGQKQREEMKSLQEALQNQ-------LKETSEKAEKHQATINFLKTEVERKSK 124
++Q+ Q++ EM+ L+E L+N+ +E + EK Q T+ +KT + K
Sbjct: 874 ELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDD 933
Query: 125 MIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQK 184
++ LQ + +++L S IH + I Q ++LR + L + + L+ K
Sbjct: 934 -LKQLQESLQIERDQLKS-----DIHDTVNMNIDTQ-EQLRNALESLKQHQETINTLKSK 986
Query: 185 LA 186
++
Sbjct: 987 IS 988
Score = 40.4 bits (93), Expect = 0.002
Identities = 62/322 (19%), Positives = 138/322 (42%), Gaps = 27/322 (8%)
Query: 31 LKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSL 90
L E+ +T L EL+ ++ + +L D + +T+ +++ EL K++ ++
Sbjct: 479 LSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEM-ELKLKEKNDLDEF 537
Query: 91 QEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIH 150
EAL+ + K+ E H E+ +++ + N+ L+N+L S +L
Sbjct: 538 -EALERKTKKDQEMQLIH---------EISNLKNLVKHAEVYNQDLENELSSKVELLREK 587
Query: 151 AEESKKIQAQL--KELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMK- 207
++ KK+Q + ++L K DL + + + D +Q + + E ALD + + ++
Sbjct: 588 EDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQ-MKQTLFDAETVALDAKRESAFLRS 646
Query: 208 ETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASKLPDAAAKSKPQQSASGNNESS 267
E ++L +++ + + L + +K K QSA NE +
Sbjct: 647 ENLEL------KEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAF--NEIT 698
Query: 268 QVESTKEGN-PSTTACDSQDEGRPCSMK---HKESPPSNATAETEPIPQKLQMPPCSECE 323
++ S +G P C+ + EG+ ++ +KE + A E + +L+ P
Sbjct: 699 KLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVER 758
Query: 324 VKKAPEKPLTSFEGMAAREEKI 345
++K + + + ++K+
Sbjct: 759 LRKEIQDKSEELHIITSEKDKL 780
Score = 39.7 bits (91), Expect = 0.004
Identities = 43/211 (20%), Positives = 97/211 (45%), Gaps = 20/211 (9%)
Query: 26 ELEK-QLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLL---ELGQ 81
E+E+ +L E F+E ++ LTK E D +K ++L+ K +++ L + Q
Sbjct: 1327 EMERLRLNEKFQESQEEIKSLTK---ERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQ 1383
Query: 82 KQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVER--KSKMIRDLQNENKSLKNK 139
++E+ +++E K SE + L+ E+E SK +++ +E KS+ +
Sbjct: 1384 SKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKE 1443
Query: 140 LLSGNKLCGIHAEESKKIQAQLKEL---------RYGKKDLLFKAQQLTDLEQKLAVAKN 190
+L + ES +++ +KE+ K Q+ T E ++ +++
Sbjct: 1444 KDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEK 1503
Query: 191 ELEKAALDRESQMKAMKETVQLCLTSVFRDQ 221
E E + + + Q++A+ + +Q + ++ +
Sbjct: 1504 ETEISTI--QKQLEAINDKLQNKIQEIYEKE 1532
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/195 (22%), Positives = 90/195 (46%), Gaps = 29/195 (14%)
Query: 27 LEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREE 86
L +LK + E + +++ S EL I L ++ ++ VQ LLE K +++
Sbjct: 745 LLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDD 804
Query: 87 MKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKL 146
+ + Q + K T ++ + + L + E+K KM+ + EN+ + ++++ +K
Sbjct: 805 LATTQ----SNYKSTDQEFQNFKT----LHMDFEQKYKMVLE---ENERMNQEIVNLSK- 852
Query: 147 CGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAM 206
E++K + L L K +L +K Q+L + +++ NE+E Q+K
Sbjct: 853 ------EAQKFDSSLGAL---KTELSYKTQELQEKTREVQERLNEME--------QLKEQ 895
Query: 207 KETVQLCLTSVFRDQ 221
E L +V R++
Sbjct: 896 LENRDSTLQTVEREK 910
Score = 37.4 bits (85), Expect = 0.020
Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 29/190 (15%)
Query: 22 QDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQ 81
QD + L+++ +++FK T+ L G +VN + N + +L +
Sbjct: 2330 QDLKSLKEKNEKLFKNYQTLKTSLAS------GAQVNPTTQDNKNPHVTSRATQLTT--E 2381
Query: 82 KQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLL 141
K RE L+N L E E A ++ I ++ E+E + +I LQ + NK L
Sbjct: 2382 KIRE--------LENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHE-SNKCL 2432
Query: 142 SGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRES 201
K + IQ ++ G K +++ DL+ KL E K A + E
Sbjct: 2433 EKTK---------ETIQVLQDKVALGAKPY---KEEIEDLKMKLVKIDLEKMKNAKEFEK 2480
Query: 202 QMKAMKETVQ 211
++ A K TV+
Sbjct: 2481 EISATKATVE 2490
Score = 35.0 bits (79), Expect = 0.099
Identities = 37/164 (22%), Positives = 76/164 (46%), Gaps = 16/164 (9%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLEL- 79
R + EL++++KE+ + + +L+ K L+ + QSA ++ KL L
Sbjct: 645 RSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLI 704
Query: 80 -GQKQREEM--KSLQEALQNQLKETSEKAEKHQA---------TINFLKTEVERKSKMIR 127
G+ ++ + L+ + + KE +++ E+++A + L +EVER K I+
Sbjct: 705 DGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQ 764
Query: 128 DLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDL 171
D E + ++ +KL + ++Q L+E+ K DL
Sbjct: 765 DKSEELHIITSE---KDKLFSEVVHKESRVQGLLEEIGKTKDDL 805
Score = 33.9 bits (76), Expect = 0.22
Identities = 42/205 (20%), Positives = 91/205 (44%), Gaps = 18/205 (8%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
+ + + E L+ + ER + ++L + E+ I + LK ++S +T+ L G
Sbjct: 1164 KNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLR--G 1221
Query: 81 QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMI---RDLQNENKSLK 137
+ E LQ + +LK ++HQ TI+ L+ V K+ I +DL+ + L+
Sbjct: 1222 YIREIEATGLQT--KEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQ 1279
Query: 138 NKL--LSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFK--------AQQLTDLEQKLAV 187
++ L + + +E + Q + EL + K + L +K
Sbjct: 1280 EEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQE 1339
Query: 188 AKNELEKAALDRESQMKAMKETVQL 212
++ E++ +R++ +K +KE +++
Sbjct: 1340 SQEEIKSLTKERDN-LKTIKEALEV 1363
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 53.9 bits (128), Expect = 2e-07
Identities = 48/213 (22%), Positives = 98/213 (46%), Gaps = 35/213 (16%)
Query: 22 QDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKND---EQSAKTDVQKLLE 78
Q++ E+ ++L E+ ++ + R + E+D + ++SL+ + + AK +++ E
Sbjct: 577 QEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEVHTE 636
Query: 79 L-------GQKQREEMKSLQEALQNQLKETSEK---------AEKHQATINFLKTEVERK 122
+K RE+ + + L+N+L+ +K + +HQ I LKT++E+K
Sbjct: 637 ALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKK 696
Query: 123 SKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLE 182
S + ++ + GIHA E K ++ KEL + L +++ L+
Sbjct: 697 SIFYEEELSKRE-------------GIHANEIKNLK---KELHDSEGQQLALNKEIMILK 740
Query: 183 QKLAVAKNELEKAALDRESQMKAMKETVQLCLT 215
KL + E + + ES+ K E ++ LT
Sbjct: 741 DKLEKTRRESQSEREEFESEFKQQYEREKVLLT 773
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/207 (21%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 19 STRQDYEE-------LEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKT 71
+ RQ+ ++ EKQ+K + +ER + ++L + S L K + LK+ K
Sbjct: 518 AVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERL---KNQSKELKDAHCQRKL 574
Query: 72 DVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQN 131
+Q+ +E+ ++ E+ + ++ L +++ E+ + + L+ E+ R + ++L+
Sbjct: 575 AMQEFMEINER-LTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAKKELEV 633
Query: 132 ENKSLKNKLLSGNKLCGIHAEESKKIQAQL-----KELRYGKKDLLFKAQQ-----LTDL 181
++L + KL SK+++ +L K++ Y + QQ TDL
Sbjct: 634 HTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDL 693
Query: 182 EQKLAVAKNELEKAALDRESQMKAMKE 208
E+K + EL K +++K +K+
Sbjct: 694 EKKSIFYEEELSKREGIHANEIKNLKK 720
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/189 (18%), Positives = 90/189 (47%), Gaps = 17/189 (8%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
E E+++K + +E+ + R+L ++++ +Q+L+ K LE+ + +
Sbjct: 442 EAYERRIKRLEQEKLELSRKLQESTQ-------TVQALQYSTVDGPLTASKDLEI-KNLK 493
Query: 85 EEMKSLQEAL--QNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLS 142
EE++ L++ + + L++ E+A + ++ +++ K I+ LQ E + L +L+
Sbjct: 494 EEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQ 553
Query: 143 GNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQ 202
+ E K +LK+ +K + + ++ + +L K +L + D+E +
Sbjct: 554 AS-------ERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEE 606
Query: 203 MKAMKETVQ 211
+ + + V+
Sbjct: 607 VDLVMQKVE 615
Score = 37.4 bits (85), Expect = 0.020
Identities = 46/184 (25%), Positives = 83/184 (45%), Gaps = 20/184 (10%)
Query: 34 VFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQE- 92
V +RS + TS +LD VN+Q ++ + + +++ L Q++ E + LQE
Sbjct: 409 VLSDRSCLRVTAGPTSLDLD---VNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQES 465
Query: 93 -----ALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLC 147
ALQ + A K I LK E+E+ K + E+ L+ +L N +
Sbjct: 466 TQTVQALQYSTVDGPLTASK-DLEIKNLKEEIEKLRKQV----TESSHLEQQLEEANAVR 520
Query: 148 GIHAEESKKIQA---QLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMK 204
+ ++I+A Q+K L+ ++DL ++L ++L EL+ A R+ M+
Sbjct: 521 QELDDAFRQIKAYEKQIKTLQQEREDL---NKELVQASERLKNQSKELKDAHCQRKLAMQ 577
Query: 205 AMKE 208
E
Sbjct: 578 EFME 581
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 53.5 bits (127), Expect = 3e-07
Identities = 47/210 (22%), Positives = 96/210 (45%), Gaps = 28/210 (13%)
Query: 27 LEKQLKEVFKERSTI---LRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQ 83
LE Q ++ KE+ + + + T E + +L LKN ++ TD+++ L +KQ
Sbjct: 983 LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQ 1042
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKS-------------------- 123
R+E++ + L+ + S++ + QA I LK ++ +K
Sbjct: 1043 RQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMA 1102
Query: 124 -KMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDL- 181
K IR+L+++ L+ L S ++ + + +L+ L+ +D L +L
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 182 ---EQKLAVAKNELEKAALDRESQMKAMKE 208
EQ++ + K LE+ A E+Q++ M++
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQ 1192
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/210 (20%), Positives = 99/210 (47%), Gaps = 24/210 (11%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL---LELGQK 82
E+E +L++ K+RS + K +L ++ ++ S + A ++KL ++ +
Sbjct: 1593 EMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR 1652
Query: 83 QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLS 142
+ ++ ++ +E + Q KE +K + +A + L+ E+ + R Q E L +++ +
Sbjct: 1653 ELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIAN 1712
Query: 143 GNKLCGIHAEESKKIQAQLKELRYGKK----------DLLFKA-----QQLTDLE----- 182
+ + EE ++++A++ +L + D L KA Q TDL
Sbjct: 1713 SSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSH 1772
Query: 183 -QKLAVAKNELEKAALDRESQMKAMKETVQ 211
QK A+ +LE+ + + +++ M+ TV+
Sbjct: 1773 AQKNENARQQLERQNKELKVKLQEMEGTVK 1802
Score = 47.0 bits (110), Expect = 3e-05
Identities = 73/326 (22%), Positives = 135/326 (41%), Gaps = 37/326 (11%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
ELE Q+ E+ ++ + K ++ + L++LK + + EL K+ +
Sbjct: 1108 ELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
E+ L++ L+ E+A+ H+A I ++ ++ S+ + +L + + K + K
Sbjct: 1168 EVNILKKTLE-------EEAKTHEAQIQEMR---QKHSQAVEELAEQLEQTKRVKANLEK 1217
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKA 205
E ++ ++K L GK D K +++ Q+L V NE E+ + E K
Sbjct: 1218 AKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGER--VRTELADKV 1275
Query: 206 MKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASKLPDA--AAKSKPQQSASGN 263
K V+L D LS S +++ + S+L D + + +Q S +
Sbjct: 1276 TKLQVEL-------DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLS 1328
Query: 264 NESSQVESTKEGNPSTTACDSQDEGRPCSMKHKESPPSNATAETEPIPQKLQMPPCSEC- 322
+ QVE K N + ++E KH AT + K +M C
Sbjct: 1329 TKLKQVEDEK--NSFREQLEEEEEA-----KH-NLEKQIATLHAQVADMKKKMEDSVGCL 1380
Query: 323 ----EVKKAPEKPLTSFEGMAAREEK 344
EVK+ +K L EG++ R E+
Sbjct: 1381 ETAEEVKRKLQKDL---EGLSQRHEE 1403
Score = 47.0 bits (110), Expect = 3e-05
Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 11/119 (9%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
+LE+QL KER +Q+ +T ++L + + + + + + K Q +
Sbjct: 1818 QLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKD-----------QAD 1866
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
+ + + L+ QL+E E+A++ A+ L+ E+E ++ + E SLKNKL G+
Sbjct: 1867 KASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGD 1925
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/208 (24%), Positives = 92/208 (44%), Gaps = 23/208 (11%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLL-EL 79
R + E EK+ K + R+ L + + EL+ + ++ D S+K DV K + EL
Sbjct: 1466 RAEAEAREKETKALSLARA--LEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 1523
Query: 80 GQKQR------EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
+ +R EEMK+ E L+++L+ T + + + + +K + ER + RD Q+E
Sbjct: 1524 EKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG-RDEQSEE 1582
Query: 134 K---------SLKNKLLSGNKLCGIHAEESKKIQAQLKELR----YGKKDLLFKAQQLTD 180
K ++ +L K + KK++ LK+L K+ +QL
Sbjct: 1583 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK 1642
Query: 181 LEQKLAVAKNELEKAALDRESQMKAMKE 208
L+ ++ EL+ RE + KE
Sbjct: 1643 LQAQMKDCMRELDDTRASREEILAQAKE 1670
Score = 43.5 bits (101), Expect = 3e-04
Identities = 50/221 (22%), Positives = 111/221 (50%), Gaps = 26/221 (11%)
Query: 13 LPALVLSTRQDYEELEKQLKEVFKERSTILRQL--TKTSRE--LDGIKVNLQSLKNDEQS 68
L A + S ++ +E KQL+++ + +R+L T+ SRE L K N + LK+ E +
Sbjct: 1622 LEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSME-A 1680
Query: 69 AKTDVQKLLELGQKQREEMKSLQEALQNQLKETS-------EKAEKHQATINFLKTEVER 121
+Q+ L ++ + + + ++ L +++ +S E+ + +A I L+ E+E
Sbjct: 1681 EMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEE 1740
Query: 122 K---SKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQL----KELRYGKKDL--- 171
+ +++I D + +++ + L HA++++ + QL KEL+ +++
Sbjct: 1741 EQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGT 1800
Query: 172 ---LFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKET 209
+KA +T LE K+A + +L+ +R++ K ++ T
Sbjct: 1801 VKSKYKA-SITALEAKIAQLEEQLDNETKERQAACKQVRRT 1840
Score = 43.1 bits (100), Expect = 4e-04
Identities = 67/340 (19%), Positives = 146/340 (42%), Gaps = 11/340 (3%)
Query: 13 LPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTD 72
L A + + +Q+ EE+ L+ +E + L +++ L+ +E+SA+
Sbjct: 902 LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQK 961
Query: 73 VQK---LLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDL 129
+Q E K+ EE + + E +L + + E A TE E KSK + L
Sbjct: 962 LQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 1021
Query: 130 QNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQ-QLTDLEQKLAVA 188
+N+++++ L + +E +K + +L+ D + + Q Q+ +L+ +LA
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 1081
Query: 189 KNELEKAALDRESQMKAMKETVQLCLTSVFR--DQPPPPLSLITSNPTRMLLPPRNIASK 246
+ EL+ AAL R + A K + + + L ++ + R++ +
Sbjct: 1082 EEELQ-AALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEE 1140
Query: 247 LPDAAAKSKPQQSASGNNESSQVESTKEGNPSTTACDSQDEGRPCSMKHKESPPSNATAE 306
L A K++ + + ++ S +E + ++E + + +E ++ A
Sbjct: 1141 L--EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQA- 1197
Query: 307 TEPIPQKLQMPPCSECEVKKAPEKPLTSFEGMAAREEKIL 346
E + ++L+ + ++KA ++ L + G A E K+L
Sbjct: 1198 VEELAEQLEQTKRVKANLEKA-KQTLENERGELANEVKVL 1236
Score = 37.7 bits (86), Expect = 0.015
Identities = 43/229 (18%), Positives = 95/229 (41%), Gaps = 9/229 (3%)
Query: 1 MKFSPAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQ 60
+KF+ + L V + + + + L + + S + + + +L + LQ
Sbjct: 1259 VKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQ 1318
Query: 61 SLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLK-------ETSEKAEKHQATIN 113
+ S T ++++ + RE+++ +EA N K + ++ +K + ++
Sbjct: 1319 EENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVG 1378
Query: 114 FLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLF 173
L+T E K K+ +DL+ ++ + K+ + +KL +++ L +L + ++
Sbjct: 1379 CLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACN 1438
Query: 174 KAQQLTDLEQKLAVAKNELEKAA--LDRESQMKAMKETVQLCLTSVFRD 220
++ +Q LA K K A DR KET L L +
Sbjct: 1439 LEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEE 1487
Score = 30.8 bits (68), Expect = 1.9
Identities = 26/147 (17%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Query: 71 TDVQKLLELGQKQREEMKSLQE---------ALQNQLKETSEKAEKHQATINFLKTEVER 121
T V+ LL++ +++ E M +E A +N+L E + A L+ +++
Sbjct: 832 TKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQA 891
Query: 122 KSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDL 181
++++ + + L K ++C ++ + + + L+ KK + Q+L +
Sbjct: 892 ETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQ 951
Query: 182 EQKLAVAKNELEKAALDRESQMKAMKE 208
++ A+ +L+ + E+++K ++E
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEE 978
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 53.5 bits (127), Expect = 3e-07
Identities = 49/183 (26%), Positives = 91/183 (49%), Gaps = 18/183 (9%)
Query: 33 EVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQE 92
E KER ++L L +T +EL L+ L+ D + VQKL K++E LQ
Sbjct: 922 ETEKERVSLLETLLQTQKELADASQQLERLRQDMK-----VQKL-----KEQETTGILQT 971
Query: 93 ALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAE 152
LQ +E E A +H+ + L+ E + DLQ + + LK++L++ + + +
Sbjct: 972 QLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQ 1031
Query: 153 ESKKIQAQLKELRYGKKDLLFKAQQLT----DLEQKLAVAKNELEKAALDRESQMKAMKE 208
E ++ + +E +K+L + LT + EQ+L V L++A R+ ++ A+++
Sbjct: 1032 EVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLV----LQEADSIRQQELSALRQ 1087
Query: 209 TVQ 211
+Q
Sbjct: 1088 DMQ 1090
Score = 43.9 bits (102), Expect = 2e-04
Identities = 42/201 (20%), Positives = 89/201 (44%), Gaps = 18/201 (8%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSREL----------DGIKVNLQSLKNDEQSAK 70
R ++LE++L + E+S + +L R+L +G + +L+S +
Sbjct: 1263 RDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETM 1322
Query: 71 TDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQ 130
+Q L + QR E + +E LQ + + + E QA + + + + DL+
Sbjct: 1323 ASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLR 1382
Query: 131 NENKSLKNKLLSGNKLCGIHAEESKKIQAQLK-ELRYGK---KDLLFKAQQLTDLEQKLA 186
+LK K N+ E ++ +Q Q + ++ GK ++L Q L + E+++
Sbjct: 1383 TARSALKLK----NEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVE 1438
Query: 187 VAKNELEKAALDRESQMKAMK 207
+ ++++ RE Q A++
Sbjct: 1439 TLRGQIQELEKQREMQKAALE 1459
Score = 43.1 bits (100), Expect = 4e-04
Identities = 44/194 (22%), Positives = 86/194 (44%), Gaps = 14/194 (7%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
+LE Q++ V + + I ++ ELD + + +A + + + G+ E
Sbjct: 789 QLEVQIQTVTQAKEVIQGEVRCLKLELD---TERSQAEQERDAAARQLAQAEQEGKTALE 845
Query: 86 EMKSLQEALQNQLKETSEKAEK-HQATINFLKTEVERKSK----MIRDLQNENKSLK--- 137
+ K+ E NQL+E EK HQ + +ER+ +++ Q E ++++
Sbjct: 846 QQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQR 905
Query: 138 --NKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAK-NELEK 194
+ + + LC + E K+ + L+ L +K+L +QQL L Q + V K E E
Sbjct: 906 EEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQET 965
Query: 195 AALDRESQMKAMKE 208
+ + +A +E
Sbjct: 966 TGILQTQLQEAQRE 979
Score = 41.2 bits (95), Expect = 0.001
Identities = 47/210 (22%), Positives = 105/210 (50%), Gaps = 19/210 (9%)
Query: 15 ALVLSTR-QDYEELEKQLKEV-----FKERSTILRQLTKTSRELDGIKVNLQSLKNDEQS 68
+L+LS R Q+ L++QL+E KE+S + QL + R L L++L+ ++Q
Sbjct: 1770 SLLLSQREQEIVVLQQQLQEAREQGELKEQS-LQSQLDEAQRALAQRDQELEALQQEQQQ 1828
Query: 69 AKTDVQKLLELGQKQREEMKSLQEALQN---QLKETSEKAEKHQATINFLKTEVERKSKM 125
A+ +++ E + ++ L+ +L++ E+A + + + V+ ++
Sbjct: 1829 AQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEV 1888
Query: 126 IRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQ-LTDLEQK 184
+ DL+ E++ + LL+ + C AE++++ + + + L +D +AQ L + +Q+
Sbjct: 1889 LGDLRAESREQEKALLALQQQC---AEQAQEHEVETRAL----QDSWLQAQAVLKERDQE 1941
Query: 185 LAVAKNELEKAALDRESQMKAMKETVQLCL 214
L + E +++ +E +A E +Q L
Sbjct: 1942 LEALRAE-SQSSRHQEEAARARAEALQEAL 1970
Score = 40.8 bits (94), Expect = 0.002
Identities = 49/199 (24%), Positives = 86/199 (43%), Gaps = 21/199 (10%)
Query: 12 LLPALVLSTRQDYEELEKQLKEVFKERST--ILRQLTKTSRELDGIKVNLQSLKNDE-QS 68
LL A + E L+ + E + S IL + +T+R + LKN+E +S
Sbjct: 1345 LLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTAR-------SALKLKNEEVES 1397
Query: 69 AKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRD 128
+ Q L E G+ + + K+LQE L + +E+ E EVE I++
Sbjct: 1398 ERERAQALQEQGELKVAQGKALQENLALLTQTLAEREE-----------EVETLRGQIQE 1446
Query: 129 LQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVA 188
L+ + + K L + +E Q Q++EL + L + + EQKL V
Sbjct: 1447 LEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQ 1506
Query: 189 KNELEKAALDRESQMKAMK 207
+ ++ + DRE+Q ++
Sbjct: 1507 REQIRELEKDRETQRNVLE 1525
Score = 40.0 bits (92), Expect = 0.003
Identities = 51/223 (22%), Positives = 94/223 (42%), Gaps = 44/223 (19%)
Query: 9 LLPLLPALVLSTRQDYEELEKQLKEVFKERSTI-------LRQLTKTSRELDGIKVNLQS 61
+L LP V Q +Q++E+ K+R T L +L K + ++ + +Q
Sbjct: 1488 VLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQD 1547
Query: 62 LKN------------DEQSAKTDVQ-KLLELGQKQREEMKSLQEALQNQLKETSEKAEKH 108
LK +E K + Q KL++ + QRE + L L+E S+
Sbjct: 1548 LKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQ----- 1602
Query: 109 QATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGK 168
E++ +S I DL++ + L +L + +E K + Q++EL+ K
Sbjct: 1603 ---------ELQAQSSQIHDLESHSTVLARELQERD-------QEVKSQREQIEELQRQK 1646
Query: 169 KDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQ 211
+ L Q L +Q+L + K ++ R Q K ++E ++
Sbjct: 1647 EHL---TQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLE 1686
Score = 37.0 bits (84), Expect = 0.026
Identities = 60/255 (23%), Positives = 105/255 (41%), Gaps = 51/255 (20%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQK 82
D E EK+ + ++++ + + QL K LQ+ D Q K ++QK L
Sbjct: 646 DLAEAEKRREALWEKNTHLEAQLQKAEEA----GAELQADLRDIQEEKEEIQKKLS---- 697
Query: 83 QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLS 142
E + QEA QL++ ++A++ + L V+ K ++R E +L+ +L +
Sbjct: 698 ---ESRHQQEAATTQLEQLHQEAKRQE---EVLARAVQEKEALVR----EKAALEVRLQA 747
Query: 143 GNKLCGIHAEESKKIQAQLKELRYGKKDL---LFKAQQLTDLEQKLAVAKNELEKAALDR 199
+ + + + QL+ L K+ L LF+AQQ + + V K +LE +
Sbjct: 748 VER-------DRQDLAEQLQGLSSAKELLESSLFEAQQQNSV---IEVTKGQLE-VQIQT 796
Query: 200 ESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASKLPDAAAKSKPQQS 259
+Q K + + CL L L T R+ A + DAAA+ Q
Sbjct: 797 VTQAKEVIQGEVRCL----------KLELDTE---------RSQAEQERDAAARQLAQAE 837
Query: 260 ASGNNESSQVESTKE 274
G Q ++ E
Sbjct: 838 QEGKTALEQQKAAHE 852
Score = 36.2 bits (82), Expect = 0.044
Identities = 51/203 (25%), Positives = 85/203 (41%), Gaps = 31/203 (15%)
Query: 14 PALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDV 73
PA +L +ELEK+ ERS L QL K+ +L+ K + Q T++
Sbjct: 243 PAQLLLLLAKTQELEKEA----HERSQELIQL-KSQGDLE---------KAELQDRVTEL 288
Query: 74 QKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
LL QKQ E+ + + +A L+ET E E + + +E ++ + R+ Q E
Sbjct: 289 SALLTQSQKQNEDYEKMIKA----LRETVEILETNHTEL------MEHEASLSRNAQEEK 338
Query: 134 KSLKNKLLSGNKLCGIHAEESKKI-QAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNEL 192
SL+ + + + EE I Q E +F D ++ L + ++ L
Sbjct: 339 LSLQQVI---KDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVL 395
Query: 193 ---EKAALDRESQMKAMKETVQL 212
+A D Q+ +E V L
Sbjct: 396 TRRRQAVQDLRQQLAGCQEAVNL 418
Score = 33.9 bits (76), Expect = 0.22
Identities = 44/213 (20%), Positives = 91/213 (42%), Gaps = 28/213 (13%)
Query: 28 EKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDV-QKLLELGQKQR-- 84
E+ + E+ +T+ ++ +L V L +L K + Q+LL+L ++ +
Sbjct: 574 EQSIAELSSSENTLKTEVA----DLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSV 629
Query: 85 ----EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKM-------IRDLQNEN 133
E + + ALQ L E ++ E L+ ++++ + +RD+Q E
Sbjct: 630 CSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEK 689
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQ-AQLKELRYGKKDLLFKAQQ----LTDLEQKLAVA 188
+ ++ KL H +E+ Q QL + ++++L +A Q L + L V
Sbjct: 690 EEIQKKLSESR-----HQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVR 744
Query: 189 KNELEKAALDRESQMKAMKETVQLCLTSVFRDQ 221
+E+ D Q++ + +L +S+F Q
Sbjct: 745 LQAVERDRQDLAEQLQGLSSAKELLESSLFEAQ 777
Score = 32.3 bits (72), Expect = 0.64
Identities = 42/209 (20%), Positives = 96/209 (45%), Gaps = 18/209 (8%)
Query: 24 YEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQ-K 82
Y+E +QL++ +R LR + + L+ +SL Q + +Q+ LGQ +
Sbjct: 2033 YQEDVQQLQQALAQRDEELRHQQEREQLLE------KSLAQRVQ--ENMIQEKQNLGQER 2084
Query: 83 QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMI----RDLQNENKSLKN 138
+ EE++ L ++++ +L+ T A+K Q + +T+ + + + E +SLK
Sbjct: 2085 EEEEIRGLHQSVR-ELQLTL--AQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKL 2141
Query: 139 KLLSGNKLCGIHAEESKKIQAQLKELRYGKK--DLLFKAQQLTDLEQKLAVAKNELEKAA 196
L + ++ Q + +E+ + +K DL Q L L+ +
Sbjct: 2142 DSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASV 2201
Query: 197 LDRESQMKAMKETVQLCLTSVFRDQPPPP 225
L+R+S+ + +++ ++L ++ +++ P
Sbjct: 2202 LERDSEQQRLQDELELTRRALEKERLHSP 2230
Score = 28.9 bits (63), Expect = 7.1
Identities = 41/196 (20%), Positives = 81/196 (41%), Gaps = 36/196 (18%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQK 82
DY++ +K L T++R + R+ +Q L+ + V L + +
Sbjct: 380 DYQDADKAL--------TLVRSVLTRRRQA------VQDLRQQLAGCQEAVNLLQQQHDQ 425
Query: 83 QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKL-- 140
EE K+L++ LQ K T E+ T++ L+ EV+ SK LQ + L+ +L
Sbjct: 426 WEEEGKALRQRLQ---KLTGERDTLAGQTVD-LQGEVDSLSKERELLQKAREELRQQLEV 481
Query: 141 ----------------LSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQK 184
L G+ G E+ +++ ++E ++ L+ + ++ +
Sbjct: 482 LEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSE 541
Query: 185 LAVAKNELEKAALDRE 200
L + LE + L+ E
Sbjct: 542 LITLREALESSHLEGE 557
>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
Length = 1711
Score = 53.1 bits (126), Expect = 4e-07
Identities = 42/177 (23%), Positives = 89/177 (50%), Gaps = 6/177 (3%)
Query: 27 LEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREE 86
LEKQ + V +E+ + +QL + S L K + LK+ Q K +Q+ EL ++ E
Sbjct: 531 LEKQHRVVRQEKEELHKQLVEASERL---KSQAKELKDAHQQRKLALQEFSELNERM-AE 586
Query: 87 MKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKL 146
+++ ++ + QL++ E+ E ++ ++ E+ R K+ ++L+ + + KL
Sbjct: 587 LRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKL 646
Query: 147 CGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
K+++++L+ L+ K A + +Q+++ K+ELEK L E ++
Sbjct: 647 REHSENFCKQMESELEALKV--KQGGRGAGATLEHQQEISKIKSELEKKVLFYEEEL 701
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/189 (17%), Positives = 97/189 (51%), Gaps = 20/189 (10%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
E E++++ + +E+ + R+L ++++ + + + ++L N + + +K
Sbjct: 441 EAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKEI---------KKLN 491
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
EE+ E L+N++ +++ + + T+ L+ E E ++ +R L+ +++ ++ + +
Sbjct: 492 EEI----ERLKNKIADSNRLERQLEDTVA-LRQEREDSTQRLRGLEKQHRVVRQEKEELH 546
Query: 145 KLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLA---VAKNELEKAALDRES 201
K E S+++++Q KEL+ + Q+ ++L +++A K ++ + D+E
Sbjct: 547 KQL---VEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEE 603
Query: 202 QMKAMKETV 210
+M+ + V
Sbjct: 604 EMEVATQKV 612
Score = 31.2 bits (69), Expect = 1.4
Identities = 30/112 (26%), Positives = 54/112 (48%), Gaps = 8/112 (7%)
Query: 18 LSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLL 77
+S +D + L E LR + SR LD + +S K D SA+ ++Q L
Sbjct: 825 VSDEKDARGYLQALASKMTEELEALRSSSLGSRTLDPLWKVRRSQKLD-MSARLELQSAL 883
Query: 78 ELG----QKQREEMKSLQEA---LQNQLKETSEKAEKHQATINFLKTEVERK 122
E Q +EE++ +++A L+++LK++ K + + LK ++E K
Sbjct: 884 EAEIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEK 935
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 53.1 bits (126), Expect = 4e-07
Identities = 48/185 (25%), Positives = 89/185 (48%), Gaps = 20/185 (10%)
Query: 22 QDYEELEKQLKEVFKERSTILRQLTKT----SRELDGIKVNLQSLKNDEQSAKTDVQKLL 77
+D +L Q K +E +TI+ QL REL + +LQS+K + ++Q+L+
Sbjct: 663 KDLSDLTAQAKSRDEETATIITQLKLERDVHQRELKDLTSSLQSVKTKHEQ---NIQELM 719
Query: 78 ELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKS-- 135
+ +K++ E ++ L+ + E A+ H+ + LK++ +R ++ + +NENK
Sbjct: 720 KHFKKEKSEAENHIRTLKAESLEEKNMAKIHRGQLEKLKSQCDRLTEELTQNENENKKLK 779
Query: 136 -----LKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKN 190
LK++L K I E ++ ++E R KD L + T+ E L V
Sbjct: 780 LKYQCLKDQLEEREKHISIEEEHLRR----MEEARLQLKDQLLCLE--TEQESILGVIGK 833
Query: 191 ELEKA 195
E++ A
Sbjct: 834 EIDAA 838
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/188 (19%), Positives = 86/188 (45%), Gaps = 19/188 (10%)
Query: 28 EKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEM 87
+ + K +E + L + K D ++ LQ L+ + ++ + EL +++++++
Sbjct: 193 DAETKRALEELTEKLNEAQKQEVVSDRVERRLQELEREMRTER-------ELVERRQDQL 245
Query: 88 KSLQEALQNQLKETSEKAEKHQATI-NFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKL 146
+ LQ LK+ KA++H+ I N L+ K+++ ++L+ + L G++
Sbjct: 246 GLMSLQLQEALKKQEAKADEHEGAIKNKLRQTETEKNQLEQELELSRRLLNQS--EGSRE 303
Query: 147 CGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNE-------LEKAALDR 199
+H E +++ QL + +K L + Q++ + + E +E+ D
Sbjct: 304 TLLHQVE--ELRTQLTKAEGDRKGLQHQVSQISKQQSNYQDEQGEDWRFRRGVEREKQDL 361
Query: 200 ESQMKAMK 207
E QM ++
Sbjct: 362 EKQMSDLR 369
Score = 33.5 bits (75), Expect = 0.29
Identities = 43/214 (20%), Positives = 94/214 (43%), Gaps = 31/214 (14%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKTSRELD-GIKVNLQSLKN-----------DEQSAK 70
+ EE+++ ++ KE++ + Q+ +REL+ G K LQ L + +
Sbjct: 380 ELEEVKRCMERKDKEKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEAERKH 439
Query: 71 TDVQKLLELGQKQREEMKSLQEALQ--NQLKETSEKAEKHQATINFLKTEVERK-----S 123
D+Q + EL + + K + L Q + E+AEK + + E R+
Sbjct: 440 ADLQ-ISELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQWKLKHK 498
Query: 124 KMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDL-------LFKAQ 176
K+ R L+ +++++ N++ E ++ A L+++ +K+L + +
Sbjct: 499 KLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEE 558
Query: 177 QLTDLEQKLAVAKNELEKAALDRESQMKAMKETV 210
+L E+KL +++ D E ++K +T+
Sbjct: 559 ELHSKEEKL----RDIKSHQADLELEVKNSLDTI 588
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/203 (22%), Positives = 94/203 (46%), Gaps = 15/203 (7%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKV---NLQSLKNDEQSAKTDVQKLL 77
RQ E EKQ+K + E++ + + +REL G ++ NLQ ++ K ++K L
Sbjct: 748 RQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKEL 807
Query: 78 ELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDL-------- 129
++ +++ E ++Q ++ET K + + N L +++E+ + + D+
Sbjct: 808 QILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKD 867
Query: 130 QNENKSLKNKLLSGNKLCGI---HAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLA 186
+ E + +K K N + I + S ++ ELR ++D+ +LT + +
Sbjct: 868 EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS 927
Query: 187 VAKNELEKAALDRE-SQMKAMKE 208
+ +E + E SQ +A K+
Sbjct: 928 FLQKSIEDMTVKAEQSQQEAAKK 950
Score = 47.0 bits (110), Expect = 3e-05
Identities = 71/305 (23%), Positives = 121/305 (39%), Gaps = 43/305 (14%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQK 82
D + L K E E + +QL +++ +++ KN E S + + + L
Sbjct: 729 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIE----KNAESSKASSITREL----- 779
Query: 83 QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLS 142
Q E+K LQ L E S+ E + + LK + S+ +Q + NKL
Sbjct: 780 QGRELKLTN--LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQ 837
Query: 143 GNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE-------KA 195
E+ + + L++LR D+ K ++ + E++L AK +LE K
Sbjct: 838 -------KEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKM 890
Query: 196 ALDRESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASKLPDAAAKS- 254
+ D SQ+ M + ++L RD L L +N L + D K+
Sbjct: 891 SGDNSSQLTKMNDELRL----KERDVEELQLKLTKANENASFL-----QKSIEDMTVKAE 941
Query: 255 KPQQSASGNNESSQVESTKEGNPSTTACDSQDEGRPCSMKHKESPPSNATAET----EPI 310
+ QQ A+ +E E KE + + + E + ++ AT+ET E I
Sbjct: 942 QSQQEAAKKHE----EEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEI 997
Query: 311 PQKLQ 315
Q LQ
Sbjct: 998 LQNLQ 1002
Score = 45.1 bits (105), Expect = 1e-04
Identities = 38/189 (20%), Positives = 91/189 (48%), Gaps = 9/189 (4%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
+E ++ ++++ ER ++ K + + I+ L ++ Q +LEL K
Sbjct: 358 KEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHD------QHVLELEAKM- 410
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
++++++ EA + E + E+ + + L+ VE +S DL+ S K++++
Sbjct: 411 DQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELE 470
Query: 145 KLCGIHAEESKKIQAQLKELR-YGKKDL-LFKAQQLTDLEQKLAVAKNELEKAALDRESQ 202
K + +E +++ +L+ + G D+ L Q+++ L++KL V + + ++ +
Sbjct: 471 KDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEH 530
Query: 203 MKAMKETVQ 211
A +ET Q
Sbjct: 531 FGAREETHQ 539
Score = 41.6 bits (96), Expect = 0.001
Identities = 55/213 (25%), Positives = 100/213 (46%), Gaps = 35/213 (16%)
Query: 22 QDYEELEKQLKEVFKERSTILRQL-------------TKTSRE--LDGIKVNLQSLKNDE 66
++ +ELE++L ++ K+ T Q TKT E L ++ L ++
Sbjct: 953 EEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKL 1012
Query: 67 QSAKTD----VQKLLELGQKQREEMKSLQ---EALQNQLKETSEKAEKHQATINFLKTEV 119
+ A+ + +Q+L EL +KQ ++ K+ Q +A+Q + T EK E T+ L+
Sbjct: 1013 KGAREENSGLLQELEEL-RKQADKAKAAQTAEDAMQIMEQMTKEKTE----TLASLEDTK 1067
Query: 120 ERKSKMIRDLQNENKSLKNKLLSG----NKLCGIHAEESKKIQAQLKELRYGKKDLLFKA 175
+ +K LQNE +LK L NK + E++K++ KE+ K+ K+
Sbjct: 1068 QTNAK----LQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKS 1123
Query: 176 QQLTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
QQL+ L+++ EL ++ + S K +E
Sbjct: 1124 QQLSALQEENVKLAEELGRSRDEVTSHQKLEEE 1156
Score = 40.0 bits (92), Expect = 0.003
Identities = 44/191 (23%), Positives = 87/191 (45%), Gaps = 14/191 (7%)
Query: 22 QDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQ 81
+D EEL+ +L + + S + + + + + + + ++ K E+ K +KL +L +
Sbjct: 910 RDVEELQLKLTKANENASFLQKSIEDMTVKAE--QSQQEAAKKHEEEKKELERKLSDLEK 967
Query: 82 KQREEMKSLQEALQNQLKETSEKAEKHQATI-NFLKTEVERKSKMIRDLQNENKSLKNKL 140
K QE + TSE KH+ + N KT ++ + K ++ + EN L +L
Sbjct: 968 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDK-LKGAREENSGLLQEL 1026
Query: 141 LSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLE---QKLAVAKNELEKAAL 197
K A+++K Q ++ ++ K + L LE Q A +NEL+
Sbjct: 1027 EELRK----QADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL-- 1080
Query: 198 DRESQMKAMKE 208
+E+ +K ++E
Sbjct: 1081 -KENNLKNVEE 1090
Score = 37.4 bits (85), Expect = 0.020
Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 36/188 (19%)
Query: 23 DYEELEKQLKEV---FKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLEL 79
D E+L + L ++ F+E+ QL K +L+ + + D S T + L L
Sbjct: 848 DLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRL 907
Query: 80 GQKQREEM---------------KSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSK 124
++ EE+ KS+++ + E A+KH+ K E+ERK
Sbjct: 908 KERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE----KKELERK-- 961
Query: 125 MIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQ-LTDLEQ 183
+ DL+ + ++ N+ E + + E + +++L Q+ L D E
Sbjct: 962 -LSDLEKKMETSHNQC----------QELKARYERATSETKTKHEEILQNLQKTLLDTED 1010
Query: 184 KLAVAKNE 191
KL A+ E
Sbjct: 1011 KLKGAREE 1018
Score = 37.0 bits (84), Expect = 0.026
Identities = 49/202 (24%), Positives = 88/202 (43%), Gaps = 31/202 (15%)
Query: 13 LPALVLSTRQDYEELEKQLKEVFKERSTILRQL--TKTSRELD---GIKVNLQSLKNDEQ 67
L +S + ELEK L +E + + R+L K + ++D + + SL+ +
Sbjct: 455 LEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLE 514
Query: 68 SAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIR 127
+TD Q+ E+ SL+E + E HQ I L T E+ SK
Sbjct: 515 VTRTDHQR----------EITSLKEHF-------GAREETHQKEIKALYTATEKLSK--- 554
Query: 128 DLQNENKSLKNKLLSGNK-LCGIHAEESKKIQAQLKELRYGKKDLLFK-AQQLTDLEQKL 185
EN+SLK+KL NK + A K++ + + ++L ++ L +
Sbjct: 555 ----ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEF 610
Query: 186 AVAKNELEKAALDRESQMKAMK 207
A K ++EK LD + +++ ++
Sbjct: 611 AELKTQIEKMRLDYQHEIENLQ 632
Score = 36.6 bits (83), Expect = 0.034
Identities = 71/327 (21%), Positives = 128/327 (39%), Gaps = 40/327 (12%)
Query: 13 LPALVLSTRQDYEELEKQLKEVFKERSTILRQ-LTKTSRELDGIKVNLQSLKNDEQSAKT 71
L L + ++ EEL K KE T+ Q + + +E++ +K + +
Sbjct: 1077 LDTLKENNLKNVEELNKS-----KELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQE 1131
Query: 72 DVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEV-ERKSKMIRDLQ 130
+ KL E + R+E+ S Q K E+ ++ +N E+ +R+SK I+D
Sbjct: 1132 ENVKLAEELGRSRDEVTSHQ------------KLEEERSVLNNQLLEMKKRESKFIKDAD 1179
Query: 131 NENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKN 190
E SL+ + + L E +K++ ++ LR G+ A+ L + Q L K
Sbjct: 1180 EEKASLQKSISITSALLTEKDAELEKLRNEVTVLR-GEN---ASAKSLHSVVQTLESDKV 1235
Query: 191 ELEKAALDRESQMKAMKETVQLCL----TSVFRDQPPPPLSLITSNPTRMLLPPRNIASK 246
+LE + E Q+K K + T D+ + N + L +N K
Sbjct: 1236 KLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLK 1295
Query: 247 -----LPDAAAKSKPQQSASGNNESSQVESTKEGNPSTTACDSQD----EGRPCSMKHKE 297
+ +AA + +++ + +S K+ CD D E P + E
Sbjct: 1296 MKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLFCDICDCFDLHDTEDCPTQAQMSE 1355
Query: 298 SPPSNATAETEPIPQKLQMPPCSECEV 324
PP + T + + P C CE+
Sbjct: 1356 DPPHS----THHGSRGEERPYCEICEM 1378
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/203 (22%), Positives = 94/203 (46%), Gaps = 15/203 (7%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKV---NLQSLKNDEQSAKTDVQKLL 77
RQ E EKQ+K + E++ + + +REL G ++ NLQ ++ K ++K L
Sbjct: 783 RQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKEL 842
Query: 78 ELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDL-------- 129
++ +++ E ++Q ++ET K + + N L +++E+ + + D+
Sbjct: 843 QILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKD 902
Query: 130 QNENKSLKNKLLSGNKLCGI---HAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLA 186
+ E + +K K N + I + S ++ ELR ++D+ +LT + +
Sbjct: 903 EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS 962
Query: 187 VAKNELEKAALDRE-SQMKAMKE 208
+ +E + E SQ +A K+
Sbjct: 963 FLQKSIEDMTVKAEQSQQEAAKK 985
Score = 47.0 bits (110), Expect = 3e-05
Identities = 71/305 (23%), Positives = 121/305 (39%), Gaps = 43/305 (14%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQK 82
D + L K E E + +QL +++ +++ KN E S + + + L
Sbjct: 764 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIE----KNAESSKASSITREL----- 814
Query: 83 QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLS 142
Q E+K LQ L E S+ E + + LK + S+ +Q + NKL
Sbjct: 815 QGRELKLTN--LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQ 872
Query: 143 GNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE-------KA 195
E+ + + L++LR D+ K ++ + E++L AK +LE K
Sbjct: 873 -------KEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKM 925
Query: 196 ALDRESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASKLPDAAAKS- 254
+ D SQ+ M + ++L RD L L +N L + D K+
Sbjct: 926 SGDNSSQLTKMNDELRL----KERDVEELQLKLTKANENASFL-----QKSIEDMTVKAE 976
Query: 255 KPQQSASGNNESSQVESTKEGNPSTTACDSQDEGRPCSMKHKESPPSNATAET----EPI 310
+ QQ A+ +E E KE + + + E + ++ AT+ET E I
Sbjct: 977 QSQQEAAKKHE----EEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEI 1032
Query: 311 PQKLQ 315
Q LQ
Sbjct: 1033 LQNLQ 1037
Score = 41.6 bits (96), Expect = 0.001
Identities = 55/213 (25%), Positives = 100/213 (46%), Gaps = 35/213 (16%)
Query: 22 QDYEELEKQLKEVFKERSTILRQL-------------TKTSRE--LDGIKVNLQSLKNDE 66
++ +ELE++L ++ K+ T Q TKT E L ++ L ++
Sbjct: 988 EEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKL 1047
Query: 67 QSAKTD----VQKLLELGQKQREEMKSLQ---EALQNQLKETSEKAEKHQATINFLKTEV 119
+ A+ + +Q+L EL +KQ ++ K+ Q +A+Q + T EK E T+ L+
Sbjct: 1048 KGAREENSGLLQELEEL-RKQADKAKAAQTAEDAMQIMEQMTKEKTE----TLASLEDTK 1102
Query: 120 ERKSKMIRDLQNENKSLKNKLLSG----NKLCGIHAEESKKIQAQLKELRYGKKDLLFKA 175
+ +K LQNE +LK L NK + E++K++ KE+ K+ K+
Sbjct: 1103 QTNAK----LQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKS 1158
Query: 176 QQLTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
QQL+ L+++ EL ++ + S K +E
Sbjct: 1159 QQLSALQEENVKLAEELGRSRDEVTSHQKLEEE 1191
Score = 40.0 bits (92), Expect = 0.003
Identities = 44/191 (23%), Positives = 87/191 (45%), Gaps = 14/191 (7%)
Query: 22 QDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQ 81
+D EEL+ +L + + S + + + + + + + ++ K E+ K +KL +L +
Sbjct: 945 RDVEELQLKLTKANENASFLQKSIEDMTVKAE--QSQQEAAKKHEEEKKELERKLSDLEK 1002
Query: 82 KQREEMKSLQEALQNQLKETSEKAEKHQATI-NFLKTEVERKSKMIRDLQNENKSLKNKL 140
K QE + TSE KH+ + N KT ++ + K ++ + EN L +L
Sbjct: 1003 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDK-LKGAREENSGLLQEL 1061
Query: 141 LSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLE---QKLAVAKNELEKAAL 197
K A+++K Q ++ ++ K + L LE Q A +NEL+
Sbjct: 1062 EELRK----QADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTL-- 1115
Query: 198 DRESQMKAMKE 208
+E+ +K ++E
Sbjct: 1116 -KENNLKNVEE 1125
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/197 (18%), Positives = 90/197 (45%), Gaps = 27/197 (13%)
Query: 17 VLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL 76
VL ++L ++ +E+ +L QL + R+++ ++ ++ +E K D++
Sbjct: 403 VLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVE----EESITKGDLETQ 458
Query: 77 LELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSL 136
+L + +K L+++L F KT+ ++ + + D + S
Sbjct: 459 TKL---EHARIKELEQSLL------------------FEKTKADKLQRELEDTRVATVSE 497
Query: 137 KNKLLSGNKLCGIHAEESKKIQAQLKELR-YGKKDL-LFKAQQLTDLEQKLAVAKNELEK 194
K++++ K + +E +++ +L+ + G D+ L Q+++ L++KL V + + ++
Sbjct: 498 KSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQR 557
Query: 195 AALDRESQMKAMKETVQ 211
+ A +ET Q
Sbjct: 558 EITSLKEHFGAREETHQ 574
Score = 37.7 bits (86), Expect = 0.015
Identities = 44/189 (23%), Positives = 83/189 (43%), Gaps = 14/189 (7%)
Query: 26 ELEKQLKEVFKERSTIL---RQLTKTSRELDGIKVNLQSLK--NDEQSAKTDVQKLLELG 80
ELE E+S I+ + L +E+ ++ L+S K D + + +Q++ L
Sbjct: 486 ELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQEISSLQ 545
Query: 81 QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKL 140
+K Q + + + + E HQ I L T E+ SK EN+SLK+KL
Sbjct: 546 EKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSK-------ENESLKSKL 598
Query: 141 LSGNK-LCGIHAEESKKIQAQLKELRYGKKDLLFK-AQQLTDLEQKLAVAKNELEKAALD 198
NK + A K++ + + ++L ++ L + A K ++EK LD
Sbjct: 599 EHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLD 658
Query: 199 RESQMKAMK 207
+ +++ ++
Sbjct: 659 YQHEIENLQ 667
Score = 37.4 bits (85), Expect = 0.020
Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 36/188 (19%)
Query: 23 DYEELEKQLKEV---FKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLEL 79
D E+L + L ++ F+E+ QL K +L+ + + D S T + L L
Sbjct: 883 DLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRL 942
Query: 80 GQKQREEM---------------KSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSK 124
++ EE+ KS+++ + E A+KH+ K E+ERK
Sbjct: 943 KERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE----KKELERK-- 996
Query: 125 MIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQ-LTDLEQ 183
+ DL+ + ++ N+ E + + E + +++L Q+ L D E
Sbjct: 997 -LSDLEKKMETSHNQC----------QELKARYERATSETKTKHEEILQNLQKTLLDTED 1045
Query: 184 KLAVAKNE 191
KL A+ E
Sbjct: 1046 KLKGAREE 1053
Score = 36.6 bits (83), Expect = 0.034
Identities = 71/327 (21%), Positives = 128/327 (39%), Gaps = 40/327 (12%)
Query: 13 LPALVLSTRQDYEELEKQLKEVFKERSTILRQ-LTKTSRELDGIKVNLQSLKNDEQSAKT 71
L L + ++ EEL K KE T+ Q + + +E++ +K + +
Sbjct: 1112 LDTLKENNLKNVEELNKS-----KELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQE 1166
Query: 72 DVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEV-ERKSKMIRDLQ 130
+ KL E + R+E+ S Q K E+ ++ +N E+ +R+SK I+D
Sbjct: 1167 ENVKLAEELGRSRDEVTSHQ------------KLEEERSVLNNQLLEMKKRESKFIKDAD 1214
Query: 131 NENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKN 190
E SL+ + + L E +K++ ++ LR G+ A+ L + Q L K
Sbjct: 1215 EEKASLQKSISITSALLTEKDAELEKLRNEVTVLR-GEN---ASAKSLHSVVQTLESDKV 1270
Query: 191 ELEKAALDRESQMKAMKETVQLCL----TSVFRDQPPPPLSLITSNPTRMLLPPRNIASK 246
+LE + E Q+K K + T D+ + N + L +N K
Sbjct: 1271 KLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLK 1330
Query: 247 -----LPDAAAKSKPQQSASGNNESSQVESTKEGNPSTTACDSQD----EGRPCSMKHKE 297
+ +AA + +++ + +S K+ CD D E P + E
Sbjct: 1331 MKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLFCDICDCFDLHDTEDCPTQAQMSE 1390
Query: 298 SPPSNATAETEPIPQKLQMPPCSECEV 324
PP + T + + P C CE+
Sbjct: 1391 DPPHS----THHGSRGEERPYCEICEM 1413
Score = 33.5 bits (75), Expect = 0.29
Identities = 45/207 (21%), Positives = 87/207 (42%), Gaps = 40/207 (19%)
Query: 31 LKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSL 90
L+E KE+ + QL R+L+ +V + S ++++ L L + ++
Sbjct: 353 LQEALKEKQQHIEQLL-AERDLERAEVAKAT------SHVGEIEQELALARDGHDQHVLE 405
Query: 91 QEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQ---NENKSLKNKLLSGNKLC 147
EA +QL+ E A++ + L ++E + + + DLQ E K L + KL
Sbjct: 406 LEAKMDQLRTMVEAADREKVE---LLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLE 462
Query: 148 GIHAEE-----------SKKIQAQLKELRYG-----------KKDLLFKAQQLTDLEQKL 185
+E + K+Q +L++ R +KDL + Q++ +L ++L
Sbjct: 463 HARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRL 522
Query: 186 AVAKNELEKAALDRESQMKAMKETVQL 212
E K A D + + ++E L
Sbjct: 523 -----ESNKPAGDVDMSLSLLQEISSL 544
>gi|35038601 spindle assembly abnormal protein 6 [Homo sapiens]
Length = 657
Score = 52.8 bits (125), Expect = 5e-07
Identities = 49/182 (26%), Positives = 95/182 (52%), Gaps = 19/182 (10%)
Query: 25 EELEKQLKEVF---KERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQ 81
EEL++ +EV +E ST+ + + + ++ ++ + L EQ K Q +L
Sbjct: 287 EELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVL---EQEIKDKDQLVL---- 339
Query: 82 KQREEMKSLQEALQNQLKETSEKAE----KHQATINFLKTEVERKSKMIRDLQNENKSLK 137
+ +E ++QE + L+E EK + K +ATI L E+ + +++I+ LQ + K+L
Sbjct: 340 RTKEAFDTIQEQ-KVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLM 398
Query: 138 NKLLSGNKLC----GIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE 193
KL N + + AE+ +K+Q + KEL+ + L K Q++ L+++L +LE
Sbjct: 399 GKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLE 458
Query: 194 KA 195
++
Sbjct: 459 ES 460
Score = 32.3 bits (72), Expect = 0.64
Identities = 55/242 (22%), Positives = 99/242 (40%), Gaps = 57/242 (23%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLL--- 77
+Q +E+ +K L+ + ++ + QL EL+ +L K S +++ L
Sbjct: 229 QQQHEQQKKDLEILHQQN---IHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGV 285
Query: 78 -ELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRD-------- 128
E Q+ ++E+ SL+ E EK EKH +N L+T+V + I+D
Sbjct: 286 EEELQRTKQEVLSLRRENSTLDVECHEK-EKH---VNQLQTKVAVLEQEIKDKDQLVLRT 341
Query: 129 ---------------------------LQNENKSLKNKLLSGNKLCGIHAEESKKIQAQL 161
L+ KSL +LL N++ + K + +L
Sbjct: 342 KEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKL 401
Query: 162 K----------ELRYGKKDLLFKAQ-QLTDLEQKLAVAKNELEKAALDRESQMKAMKETV 210
K +L K++ L K Q +L D+ Q L + + E+ K E+ +K ++E+
Sbjct: 402 KLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESK 461
Query: 211 QL 212
QL
Sbjct: 462 QL 463
>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
Length = 446
Score = 52.8 bits (125), Expect = 5e-07
Identities = 51/205 (24%), Positives = 100/205 (48%), Gaps = 27/205 (13%)
Query: 16 LVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQK 75
LV++T+ + EE+E+ KE+ KE + ++ ++ LQ K +E + K
Sbjct: 134 LVVTTQGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQK-KQEELETLQSINK 192
Query: 76 LLELGQKQRE---EMKSLQEALQNQLKETSE------KAEKHQATINFLKTEVER----- 121
LEL K+++ E + LQ QNQ K +SE + ++ QA ++ + E+E+
Sbjct: 193 KLELKVKEQKDYWETELLQLKEQNQ-KMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGD 251
Query: 122 --KSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLT 179
K++ + L+ EN L L K + KK++ +++++ + + K Q+L
Sbjct: 252 QDKTEQLEQLKKENDHLFLSLTEQRK-------DQKKLEQTVEQMKQNETTAMKKQQELM 304
Query: 180 DLEQKLA--VAKNELEKAALDRESQ 202
D L+ +++NE+ AL R+ +
Sbjct: 305 DENFDLSKRLSENEIICNALQRQKE 329
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/161 (22%), Positives = 72/161 (44%), Gaps = 14/161 (8%)
Query: 16 LVLSTRQDYEELEK-QLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQ 74
L + ++DY E E QLKE Q K S E + + + + L+ + + +++
Sbjct: 196 LKVKEQKDYWETELLQLKE----------QNQKMSSENEKMGIRVDQLQAQLSTQEKEME 245
Query: 75 KLLELGQ---KQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQN 131
KL++ Q +Q E++K + L L E + +K + T+ +K K ++L +
Sbjct: 246 KLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMD 305
Query: 132 ENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLL 172
EN L +L +C + ++++ + L+ LL
Sbjct: 306 ENFDLSKRLSENEIICNALQRQKERLEGENDLLKRENSRLL 346
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 52.4 bits (124), Expect = 6e-07
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 29/211 (13%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
R + E EK+ K + R+ L + + EL+ L++ D S+K DV K +
Sbjct: 1473 RAEAEAREKETKALSLARA--LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHEL 1530
Query: 81 QK-------QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
+K Q EEMK+ E L+++L+ T + + + + LK + ER RD QNE
Sbjct: 1531 EKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER-DLQARDEQNEE 1589
Query: 134 K---------SLKNKLLSGNKLCGIHAEESKKIQAQLKELRY-------GKKDLLFKAQQ 177
K + +L K + A KK++ LK+L G+++ + +Q
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI---KQ 1646
Query: 178 LTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
L L+ ++ + ELE A R+ KE
Sbjct: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKE 1677
Score = 50.1 bits (118), Expect = 3e-06
Identities = 46/210 (21%), Positives = 91/210 (43%), Gaps = 28/210 (13%)
Query: 27 LEKQLKEVFKERSTI---LRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQ 83
++ Q ++ KER + + LT E + NL LKN +S ++++ L+ +K
Sbjct: 990 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1049
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKS-------------------- 123
R+E++ L+ L+ + E+ QA I LK ++ +K
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1109
Query: 124 -KMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDL- 181
K IR+L+ L+ L S ++ + + +L+ L+ +D L +L
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 182 ---EQKLAVAKNELEKAALDRESQMKAMKE 208
EQ++ V K L++ E+Q++ M++
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQ 1199
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/223 (21%), Positives = 100/223 (44%), Gaps = 32/223 (14%)
Query: 20 TRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLEL 79
TRQ + +L+++ +ER+++ QL + ++ ++ +L +K +Q
Sbjct: 1328 TRQKLN-VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST 1386
Query: 80 GQKQREEMKSLQEALQNQLKETSEKA---EKHQATINFLKTEVE-------RKSKMIRDL 129
+ E K Q+ ++N ++ EKA +K + T N L+ E++ + +++ +L
Sbjct: 1387 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL 1446
Query: 130 QNENKSLKNKLLSGNKLCGIHAEESKKIQAQ--------------LKELRYGKKDL---- 171
+ + + L + +A+E + +A+ L+E K++L
Sbjct: 1447 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1506
Query: 172 -LFKAQQLTDLEQKLAVAKN--ELEKAALDRESQMKAMKETVQ 211
+ KA+ + K V KN ELEK+ E+QM+ MK ++
Sbjct: 1507 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
Score = 43.5 bits (101), Expect = 3e-04
Identities = 51/223 (22%), Positives = 99/223 (44%), Gaps = 38/223 (17%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKT-------SRELDGIKVNLQSL----KNDEQSAKT 71
D ++LE Q K R ++QL K REL+ + + + K +E+ AK+
Sbjct: 1625 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684
Query: 72 DVQKLLEL---------GQKQRE-EMKSLQEALQNQL---KETSEKAEKHQATINFLKTE 118
L++L +KQ + E + L E L + L ++ + +A I L+ E
Sbjct: 1685 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
Query: 119 VERK-------SKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELR------ 165
+E + S +R + + L N+L + + ++++ Q KELR
Sbjct: 1745 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1804
Query: 166 YGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
G FK+ + LE K+A + ++E+ A ++++ K++K+
Sbjct: 1805 EGAVKSKFKS-TIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/129 (21%), Positives = 66/129 (51%), Gaps = 11/129 (8%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
+LE+Q+++ +E+ + L + ++L I + ++ D +K+ E ++Q E
Sbjct: 1825 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVE-----------DERKMAEQYKEQAE 1873
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
+ + + L+ QL+E E++++ A L+ E++ ++ + E +LK+KL GN+
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
Query: 146 LCGIHAEES 154
+ + S
Sbjct: 1934 TSFVPSRRS 1942
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/198 (19%), Positives = 88/198 (44%), Gaps = 14/198 (7%)
Query: 28 EKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEM 87
E Q++E+ ++ + + +LT+ + K NL K + D+ L + + ++E+
Sbjct: 1191 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1250
Query: 88 KSLQEALQNQLKETSEK---AEKHQATIN----FLKTEVERKSKMIRD-------LQNEN 133
+ ++ L+ Q++E K E+ +A +N L+ EVE + M+ + L +
Sbjct: 1251 EHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE 193
SL ++L +L + + +L++L + L + + + +Q L + L
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
Query: 194 KAALDRESQMKAMKETVQ 211
D + +++ TV+
Sbjct: 1371 IQLSDSKKKLQDFASTVE 1388
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/187 (19%), Positives = 93/187 (49%), Gaps = 16/187 (8%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
EE E + +++ ER + +Q+ +L+ + Q L+ ++ +A+ ++KL
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL-------- 983
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
E+ + + N+L + + E+ + + E E K+K + L+N+++S+ ++L
Sbjct: 984 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL---- 1039
Query: 145 KLCGIHAEESKKIQAQLKEL-RYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
+ ++ +K + +L++L R + D +Q+ DL+ ++A K +L K + ++ +
Sbjct: 1040 ---EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAAL 1096
Query: 204 KAMKETV 210
+ + +
Sbjct: 1097 ARLDDEI 1103
Score = 38.1 bits (87), Expect = 0.012
Identities = 48/218 (22%), Positives = 95/218 (43%), Gaps = 45/218 (20%)
Query: 22 QDYEELEKQLKE-------VFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQ 74
Q EEL +QL++ + K + T+ ++ + EL + Q +++ ++ + VQ
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
Query: 75 KLLEL---GQKQREEMKSLQEALQNQL------------------KETSEKAEKHQATIN 113
+L G++ R E+ LQN++ K+ + + + Q T
Sbjct: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Query: 114 FLKTEVERK---SKMIRDLQNENKSLKNKL---LSGNKLCGIH--------AEESKKIQ- 158
L+ E +K S +R L+ E SL+++L + + H ++ KK+Q
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Query: 159 --AQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEK 194
+ ++ L GKK + + LT ++ A A ++LEK
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1420
Score = 37.4 bits (85), Expect = 0.020
Identities = 37/162 (22%), Positives = 80/162 (49%), Gaps = 21/162 (12%)
Query: 55 IKVNLQSLKNDE--QSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATI 112
+K LQ + +E Q+ + ++QK E QK E+K L++ +E + E+ QA
Sbjct: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-- 898
Query: 113 NFLKTEVERKSKMIR-DLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDL 171
+TE+ +++ +R L + + L+ L + +++QA+ K++
Sbjct: 899 ---ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM------- 948
Query: 172 LFKAQQLTDLEQKL---AVAKNELEKAALDRESQMKAMKETV 210
AQQ+ DLE++L A+ +L+ + E+++K +++ +
Sbjct: 949 ---AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
Score = 36.2 bits (82), Expect = 0.044
Identities = 31/186 (16%), Positives = 84/186 (45%), Gaps = 10/186 (5%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
ELE + ++ ++ + K ++ + L++LK + + EL K+ +
Sbjct: 1115 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
E+ L++AL E+ H+A + ++ ++ ++ + +L + + K + +K
Sbjct: 1175 EVTVLKKALD-------EETRSHEAQVQEMR---QKHAQAVEELTEQLEQFKRAKANLDK 1224
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKA 205
+E+ + +L+ L K+++ K ++L Q+L ++ E+A + ++
Sbjct: 1225 NKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1284
Query: 206 MKETVQ 211
++ V+
Sbjct: 1285 LQNEVE 1290
Score = 34.3 bits (77), Expect = 0.17
Identities = 42/188 (22%), Positives = 78/188 (41%), Gaps = 16/188 (8%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQS-LKNDEQSAKTDVQKLLELGQKQ 83
EE +QL+ E T L K K L+ LK+ E A + + K
Sbjct: 1588 EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--------KG 1639
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSG 143
REE LQ Q+K+ + E +A+ + + + K + L+ + L+ L +
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
Query: 144 NKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
+ E +++ +L G+ L + ++L E ++A + ELE + + M
Sbjct: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRL---EARIAQLEEELE----EEQGNM 1752
Query: 204 KAMKETVQ 211
+AM + V+
Sbjct: 1753 EAMSDRVR 1760
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 52.4 bits (124), Expect = 6e-07
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 29/211 (13%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
R + E EK+ K + R+ L + + EL+ L++ D S+K DV K +
Sbjct: 1480 RAEAEAREKETKALSLARA--LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHEL 1537
Query: 81 QK-------QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
+K Q EEMK+ E L+++L+ T + + + + LK + ER RD QNE
Sbjct: 1538 EKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER-DLQARDEQNEE 1596
Query: 134 K---------SLKNKLLSGNKLCGIHAEESKKIQAQLKELRY-------GKKDLLFKAQQ 177
K + +L K + A KK++ LK+L G+++ + +Q
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI---KQ 1653
Query: 178 LTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
L L+ ++ + ELE A R+ KE
Sbjct: 1654 LRKLQAQMKDFQRELEDARASRDEIFATAKE 1684
Score = 50.1 bits (118), Expect = 3e-06
Identities = 46/210 (21%), Positives = 91/210 (43%), Gaps = 28/210 (13%)
Query: 27 LEKQLKEVFKERSTI---LRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQ 83
++ Q ++ KER + + LT E + NL LKN +S ++++ L+ +K
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1056
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKS-------------------- 123
R+E++ L+ L+ + E+ QA I LK ++ +K
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1116
Query: 124 -KMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDL- 181
K IR+L+ L+ L S ++ + + +L+ L+ +D L +L
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 182 ---EQKLAVAKNELEKAALDRESQMKAMKE 208
EQ++ V K L++ E+Q++ M++
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQ 1206
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/223 (21%), Positives = 100/223 (44%), Gaps = 32/223 (14%)
Query: 20 TRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLEL 79
TRQ + +L+++ +ER+++ QL + ++ ++ +L +K +Q
Sbjct: 1335 TRQKLN-VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST 1393
Query: 80 GQKQREEMKSLQEALQNQLKETSEKA---EKHQATINFLKTEVE-------RKSKMIRDL 129
+ E K Q+ ++N ++ EKA +K + T N L+ E++ + +++ +L
Sbjct: 1394 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL 1453
Query: 130 QNENKSLKNKLLSGNKLCGIHAEESKKIQAQ--------------LKELRYGKKDL---- 171
+ + + L + +A+E + +A+ L+E K++L
Sbjct: 1454 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1513
Query: 172 -LFKAQQLTDLEQKLAVAKN--ELEKAALDRESQMKAMKETVQ 211
+ KA+ + K V KN ELEK+ E+QM+ MK ++
Sbjct: 1514 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Score = 43.5 bits (101), Expect = 3e-04
Identities = 51/223 (22%), Positives = 99/223 (44%), Gaps = 38/223 (17%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKT-------SRELDGIKVNLQSL----KNDEQSAKT 71
D ++LE Q K R ++QL K REL+ + + + K +E+ AK+
Sbjct: 1632 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1691
Query: 72 DVQKLLEL---------GQKQRE-EMKSLQEALQNQL---KETSEKAEKHQATINFLKTE 118
L++L +KQ + E + L E L + L ++ + +A I L+ E
Sbjct: 1692 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1751
Query: 119 VERK-------SKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELR------ 165
+E + S +R + + L N+L + + ++++ Q KELR
Sbjct: 1752 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1811
Query: 166 YGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
G FK+ + LE K+A + ++E+ A ++++ K++K+
Sbjct: 1812 EGAVKSKFKS-TIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1853
Score = 43.1 bits (100), Expect = 4e-04
Identities = 28/129 (21%), Positives = 66/129 (51%), Gaps = 11/129 (8%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
+LE+Q+++ +E+ + L + ++L I + ++ D +K+ E ++Q E
Sbjct: 1832 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVE-----------DERKMAEQYKEQAE 1880
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
+ + + L+ QL+E E++++ A L+ E++ ++ + E +LK+KL GN+
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1940
Query: 146 LCGIHAEES 154
+ + S
Sbjct: 1941 TSFVPSRRS 1949
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/198 (19%), Positives = 88/198 (44%), Gaps = 14/198 (7%)
Query: 28 EKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEM 87
E Q++E+ ++ + + +LT+ + K NL K + D+ L + + ++E+
Sbjct: 1198 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1257
Query: 88 KSLQEALQNQLKETSEK---AEKHQATIN----FLKTEVERKSKMIRD-------LQNEN 133
+ ++ L+ Q++E K E+ +A +N L+ EVE + M+ + L +
Sbjct: 1258 EHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE 193
SL ++L +L + + +L++L + L + + + +Q L + L
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377
Query: 194 KAALDRESQMKAMKETVQ 211
D + +++ TV+
Sbjct: 1378 IQLSDSKKKLQDFASTVE 1395
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/187 (19%), Positives = 93/187 (49%), Gaps = 16/187 (8%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
EE E + +++ ER + +Q+ +L+ + Q L+ ++ +A+ ++KL
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL-------- 990
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
E+ + + N+L + + E+ + + E E K+K + L+N+++S+ ++L
Sbjct: 991 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL---- 1046
Query: 145 KLCGIHAEESKKIQAQLKEL-RYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
+ ++ +K + +L++L R + D +Q+ DL+ ++A K +L K + ++ +
Sbjct: 1047 ---EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAAL 1103
Query: 204 KAMKETV 210
+ + +
Sbjct: 1104 ARLDDEI 1110
Score = 38.1 bits (87), Expect = 0.012
Identities = 48/218 (22%), Positives = 95/218 (43%), Gaps = 45/218 (20%)
Query: 22 QDYEELEKQLKE-------VFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQ 74
Q EEL +QL++ + K + T+ ++ + EL + Q +++ ++ + VQ
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1269
Query: 75 KLLEL---GQKQREEMKSLQEALQNQL------------------KETSEKAEKHQATIN 113
+L G++ R E+ LQN++ K+ + + + Q T
Sbjct: 1270 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 114 FLKTEVERK---SKMIRDLQNENKSLKNKL---LSGNKLCGIH--------AEESKKIQ- 158
L+ E +K S +R L+ E SL+++L + + H ++ KK+Q
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 159 --AQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEK 194
+ ++ L GKK + + LT ++ A A ++LEK
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1427
Score = 37.4 bits (85), Expect = 0.020
Identities = 37/162 (22%), Positives = 80/162 (49%), Gaps = 21/162 (12%)
Query: 55 IKVNLQSLKNDE--QSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATI 112
+K LQ + +E Q+ + ++QK E QK E+K L++ +E + E+ QA
Sbjct: 848 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-- 905
Query: 113 NFLKTEVERKSKMIR-DLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDL 171
+TE+ +++ +R L + + L+ L + +++QA+ K++
Sbjct: 906 ---ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM------- 955
Query: 172 LFKAQQLTDLEQKL---AVAKNELEKAALDRESQMKAMKETV 210
AQQ+ DLE++L A+ +L+ + E+++K +++ +
Sbjct: 956 ---AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 994
Score = 36.2 bits (82), Expect = 0.044
Identities = 31/186 (16%), Positives = 84/186 (45%), Gaps = 10/186 (5%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
ELE + ++ ++ + K ++ + L++LK + + EL K+ +
Sbjct: 1122 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1181
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
E+ L++AL E+ H+A + ++ ++ ++ + +L + + K + +K
Sbjct: 1182 EVTVLKKALD-------EETRSHEAQVQEMR---QKHAQAVEELTEQLEQFKRAKANLDK 1231
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKA 205
+E+ + +L+ L K+++ K ++L Q+L ++ E+A + ++
Sbjct: 1232 NKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1291
Query: 206 MKETVQ 211
++ V+
Sbjct: 1292 LQNEVE 1297
Score = 34.3 bits (77), Expect = 0.17
Identities = 42/188 (22%), Positives = 78/188 (41%), Gaps = 16/188 (8%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQS-LKNDEQSAKTDVQKLLELGQKQ 83
EE +QL+ E T L K K L+ LK+ E A + + K
Sbjct: 1595 EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--------KG 1646
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSG 143
REE LQ Q+K+ + E +A+ + + + K + L+ + L+ L +
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706
Query: 144 NKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
+ E +++ +L G+ L + ++L E ++A + ELE + + M
Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRL---EARIAQLEEELE----EEQGNM 1759
Query: 204 KAMKETVQ 211
+AM + V+
Sbjct: 1760 EAMSDRVR 1767
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 52.4 bits (124), Expect = 6e-07
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 29/211 (13%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
R + E EK+ K + R+ L + + EL+ L++ D S+K DV K +
Sbjct: 1480 RAEAEAREKETKALSLARA--LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHEL 1537
Query: 81 QK-------QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
+K Q EEMK+ E L+++L+ T + + + + LK + ER RD QNE
Sbjct: 1538 EKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER-DLQARDEQNEE 1596
Query: 134 K---------SLKNKLLSGNKLCGIHAEESKKIQAQLKELRY-------GKKDLLFKAQQ 177
K + +L K + A KK++ LK+L G+++ + +Q
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI---KQ 1653
Query: 178 LTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
L L+ ++ + ELE A R+ KE
Sbjct: 1654 LRKLQAQMKDFQRELEDARASRDEIFATAKE 1684
Score = 50.1 bits (118), Expect = 3e-06
Identities = 46/210 (21%), Positives = 91/210 (43%), Gaps = 28/210 (13%)
Query: 27 LEKQLKEVFKERSTI---LRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQ 83
++ Q ++ KER + + LT E + NL LKN +S ++++ L+ +K
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1056
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKS-------------------- 123
R+E++ L+ L+ + E+ QA I LK ++ +K
Sbjct: 1057 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1116
Query: 124 -KMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDL- 181
K IR+L+ L+ L S ++ + + +L+ L+ +D L +L
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 182 ---EQKLAVAKNELEKAALDRESQMKAMKE 208
EQ++ V K L++ E+Q++ M++
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQ 1206
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/223 (21%), Positives = 100/223 (44%), Gaps = 32/223 (14%)
Query: 20 TRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLEL 79
TRQ + +L+++ +ER+++ QL + ++ ++ +L +K +Q
Sbjct: 1335 TRQKLN-VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST 1393
Query: 80 GQKQREEMKSLQEALQNQLKETSEKA---EKHQATINFLKTEVE-------RKSKMIRDL 129
+ E K Q+ ++N ++ EKA +K + T N L+ E++ + +++ +L
Sbjct: 1394 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL 1453
Query: 130 QNENKSLKNKLLSGNKLCGIHAEESKKIQAQ--------------LKELRYGKKDL---- 171
+ + + L + +A+E + +A+ L+E K++L
Sbjct: 1454 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1513
Query: 172 -LFKAQQLTDLEQKLAVAKN--ELEKAALDRESQMKAMKETVQ 211
+ KA+ + K V KN ELEK+ E+QM+ MK ++
Sbjct: 1514 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Score = 43.5 bits (101), Expect = 3e-04
Identities = 51/223 (22%), Positives = 99/223 (44%), Gaps = 38/223 (17%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKT-------SRELDGIKVNLQSL----KNDEQSAKT 71
D ++LE Q K R ++QL K REL+ + + + K +E+ AK+
Sbjct: 1632 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1691
Query: 72 DVQKLLEL---------GQKQRE-EMKSLQEALQNQL---KETSEKAEKHQATINFLKTE 118
L++L +KQ + E + L E L + L ++ + +A I L+ E
Sbjct: 1692 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1751
Query: 119 VERK-------SKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELR------ 165
+E + S +R + + L N+L + + ++++ Q KELR
Sbjct: 1752 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1811
Query: 166 YGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
G FK+ + LE K+A + ++E+ A ++++ K++K+
Sbjct: 1812 EGAVKSKFKS-TIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1853
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/198 (19%), Positives = 88/198 (44%), Gaps = 14/198 (7%)
Query: 28 EKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEM 87
E Q++E+ ++ + + +LT+ + K NL K + D+ L + + ++E+
Sbjct: 1198 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1257
Query: 88 KSLQEALQNQLKETSEK---AEKHQATIN----FLKTEVERKSKMIRD-------LQNEN 133
+ ++ L+ Q++E K E+ +A +N L+ EVE + M+ + L +
Sbjct: 1258 EHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE 193
SL ++L +L + + +L++L + L + + + +Q L + L
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377
Query: 194 KAALDRESQMKAMKETVQ 211
D + +++ TV+
Sbjct: 1378 IQLSDSKKKLQDFASTVE 1395
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/187 (19%), Positives = 93/187 (49%), Gaps = 16/187 (8%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
EE E + +++ ER + +Q+ +L+ + Q L+ ++ +A+ ++KL
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL-------- 990
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
E+ + + N+L + + E+ + + E E K+K + L+N+++S+ ++L
Sbjct: 991 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL---- 1046
Query: 145 KLCGIHAEESKKIQAQLKEL-RYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
+ ++ +K + +L++L R + D +Q+ DL+ ++A K +L K + ++ +
Sbjct: 1047 ---EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAAL 1103
Query: 204 KAMKETV 210
+ + +
Sbjct: 1104 ARLDDEI 1110
Score = 38.1 bits (87), Expect = 0.012
Identities = 48/218 (22%), Positives = 95/218 (43%), Gaps = 45/218 (20%)
Query: 22 QDYEELEKQLKE-------VFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQ 74
Q EEL +QL++ + K + T+ ++ + EL + Q +++ ++ + VQ
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1269
Query: 75 KLLEL---GQKQREEMKSLQEALQNQL------------------KETSEKAEKHQATIN 113
+L G++ R E+ LQN++ K+ + + + Q T
Sbjct: 1270 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329
Query: 114 FLKTEVERK---SKMIRDLQNENKSLKNKL---LSGNKLCGIH--------AEESKKIQ- 158
L+ E +K S +R L+ E SL+++L + + H ++ KK+Q
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389
Query: 159 --AQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEK 194
+ ++ L GKK + + LT ++ A A ++LEK
Sbjct: 1390 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1427
Score = 37.4 bits (85), Expect = 0.020
Identities = 37/162 (22%), Positives = 80/162 (49%), Gaps = 21/162 (12%)
Query: 55 IKVNLQSLKNDE--QSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATI 112
+K LQ + +E Q+ + ++QK E QK E+K L++ +E + E+ QA
Sbjct: 848 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-- 905
Query: 113 NFLKTEVERKSKMIR-DLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDL 171
+TE+ +++ +R L + + L+ L + +++QA+ K++
Sbjct: 906 ---ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM------- 955
Query: 172 LFKAQQLTDLEQKL---AVAKNELEKAALDRESQMKAMKETV 210
AQQ+ DLE++L A+ +L+ + E+++K +++ +
Sbjct: 956 ---AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 994
Score = 36.2 bits (82), Expect = 0.044
Identities = 31/186 (16%), Positives = 84/186 (45%), Gaps = 10/186 (5%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
ELE + ++ ++ + K ++ + L++LK + + EL K+ +
Sbjct: 1122 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1181
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
E+ L++AL E+ H+A + ++ ++ ++ + +L + + K + +K
Sbjct: 1182 EVTVLKKALD-------EETRSHEAQVQEMR---QKHAQAVEELTEQLEQFKRAKANLDK 1231
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKA 205
+E+ + +L+ L K+++ K ++L Q+L ++ E+A + ++
Sbjct: 1232 NKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1291
Query: 206 MKETVQ 211
++ V+
Sbjct: 1292 LQNEVE 1297
Score = 34.3 bits (77), Expect = 0.17
Identities = 42/188 (22%), Positives = 78/188 (41%), Gaps = 16/188 (8%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQS-LKNDEQSAKTDVQKLLELGQKQ 83
EE +QL+ E T L K K L+ LK+ E A + + K
Sbjct: 1595 EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--------KG 1646
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSG 143
REE LQ Q+K+ + E +A+ + + + K + L+ + L+ L +
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706
Query: 144 NKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
+ E +++ +L G+ L + ++L E ++A + ELE + + M
Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRL---EARIAQLEEELE----EEQGNM 1759
Query: 204 KAMKETVQ 211
+AM + V+
Sbjct: 1760 EAMSDRVR 1767
Score = 32.7 bits (73), Expect = 0.49
Identities = 27/115 (23%), Positives = 60/115 (52%), Gaps = 11/115 (9%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
+LE+Q+++ +E+ TK+ ++ D + LK + D +K+ E ++Q E
Sbjct: 1832 QLEEQVEQEAREKQAA----TKSLKQKD------KKLKEILLQVE-DERKMAEQYKEQAE 1880
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKL 140
+ + + L+ QL+E E++++ A L+ E++ ++ + E +LK+KL
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 52.4 bits (124), Expect = 6e-07
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 29/211 (13%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
R + E EK+ K + R+ L + + EL+ L++ D S+K DV K +
Sbjct: 1473 RAEAEAREKETKALSLARA--LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHEL 1530
Query: 81 QK-------QREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
+K Q EEMK+ E L+++L+ T + + + + LK + ER RD QNE
Sbjct: 1531 EKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER-DLQARDEQNEE 1589
Query: 134 K---------SLKNKLLSGNKLCGIHAEESKKIQAQLKELRY-------GKKDLLFKAQQ 177
K + +L K + A KK++ LK+L G+++ + +Q
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI---KQ 1646
Query: 178 LTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
L L+ ++ + ELE A R+ KE
Sbjct: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKE 1677
Score = 50.1 bits (118), Expect = 3e-06
Identities = 46/210 (21%), Positives = 91/210 (43%), Gaps = 28/210 (13%)
Query: 27 LEKQLKEVFKERSTI---LRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQ 83
++ Q ++ KER + + LT E + NL LKN +S ++++ L+ +K
Sbjct: 990 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1049
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKS-------------------- 123
R+E++ L+ L+ + E+ QA I LK ++ +K
Sbjct: 1050 RQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA 1109
Query: 124 -KMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDL- 181
K IR+L+ L+ L S ++ + + +L+ L+ +D L +L
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 182 ---EQKLAVAKNELEKAALDRESQMKAMKE 208
EQ++ V K L++ E+Q++ M++
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQ 1199
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/223 (21%), Positives = 100/223 (44%), Gaps = 32/223 (14%)
Query: 20 TRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLEL 79
TRQ + +L+++ +ER+++ QL + ++ ++ +L +K +Q
Sbjct: 1328 TRQKLN-VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAST 1386
Query: 80 GQKQREEMKSLQEALQNQLKETSEKA---EKHQATINFLKTEVE-------RKSKMIRDL 129
+ E K Q+ ++N ++ EKA +K + T N L+ E++ + +++ +L
Sbjct: 1387 VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNL 1446
Query: 130 QNENKSLKNKLLSGNKLCGIHAEESKKIQAQ--------------LKELRYGKKDL---- 171
+ + + L + +A+E + +A+ L+E K++L
Sbjct: 1447 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1506
Query: 172 -LFKAQQLTDLEQKLAVAKN--ELEKAALDRESQMKAMKETVQ 211
+ KA+ + K V KN ELEK+ E+QM+ MK ++
Sbjct: 1507 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
Score = 43.5 bits (101), Expect = 3e-04
Identities = 51/223 (22%), Positives = 99/223 (44%), Gaps = 38/223 (17%)
Query: 23 DYEELEKQLKEVFKERSTILRQLTKT-------SRELDGIKVNLQSL----KNDEQSAKT 71
D ++LE Q K R ++QL K REL+ + + + K +E+ AK+
Sbjct: 1625 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684
Query: 72 DVQKLLEL---------GQKQRE-EMKSLQEALQNQL---KETSEKAEKHQATINFLKTE 118
L++L +KQ + E + L E L + L ++ + +A I L+ E
Sbjct: 1685 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
Query: 119 VERK-------SKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELR------ 165
+E + S +R + + L N+L + + ++++ Q KELR
Sbjct: 1745 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1804
Query: 166 YGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKE 208
G FK+ + LE K+A + ++E+ A ++++ K++K+
Sbjct: 1805 EGAVKSKFKS-TIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/198 (19%), Positives = 88/198 (44%), Gaps = 14/198 (7%)
Query: 28 EKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEM 87
E Q++E+ ++ + + +LT+ + K NL K + D+ L + + ++E+
Sbjct: 1191 EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEV 1250
Query: 88 KSLQEALQNQLKETSEK---AEKHQATIN----FLKTEVERKSKMIRD-------LQNEN 133
+ ++ L+ Q++E K E+ +A +N L+ EVE + M+ + L +
Sbjct: 1251 EHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE 193
SL ++L +L + + +L++L + L + + + +Q L + L
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
Query: 194 KAALDRESQMKAMKETVQ 211
D + +++ TV+
Sbjct: 1371 IQLSDSKKKLQDFASTVE 1388
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/187 (19%), Positives = 93/187 (49%), Gaps = 16/187 (8%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
EE E + +++ ER + +Q+ +L+ + Q L+ ++ +A+ ++KL
Sbjct: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL-------- 983
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
E+ + + N+L + + E+ + + E E K+K + L+N+++S+ ++L
Sbjct: 984 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL---- 1039
Query: 145 KLCGIHAEESKKIQAQLKEL-RYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
+ ++ +K + +L++L R + D +Q+ DL+ ++A K +L K + ++ +
Sbjct: 1040 ---EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAAL 1096
Query: 204 KAMKETV 210
+ + +
Sbjct: 1097 ARLDDEI 1103
Score = 38.1 bits (87), Expect = 0.012
Identities = 48/218 (22%), Positives = 95/218 (43%), Gaps = 45/218 (20%)
Query: 22 QDYEELEKQLKE-------VFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQ 74
Q EEL +QL++ + K + T+ ++ + EL + Q +++ ++ + VQ
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
Query: 75 KLLEL---GQKQREEMKSLQEALQNQL------------------KETSEKAEKHQATIN 113
+L G++ R E+ LQN++ K+ + + + Q T
Sbjct: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Query: 114 FLKTEVERK---SKMIRDLQNENKSLKNKL---LSGNKLCGIH--------AEESKKIQ- 158
L+ E +K S +R L+ E SL+++L + + H ++ KK+Q
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
Query: 159 --AQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEK 194
+ ++ L GKK + + LT ++ A A ++LEK
Sbjct: 1383 FASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEK 1420
Score = 37.4 bits (85), Expect = 0.020
Identities = 37/162 (22%), Positives = 80/162 (49%), Gaps = 21/162 (12%)
Query: 55 IKVNLQSLKNDE--QSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATI 112
+K LQ + +E Q+ + ++QK E QK E+K L++ +E + E+ QA
Sbjct: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA-- 898
Query: 113 NFLKTEVERKSKMIR-DLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDL 171
+TE+ +++ +R L + + L+ L + +++QA+ K++
Sbjct: 899 ---ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM------- 948
Query: 172 LFKAQQLTDLEQKL---AVAKNELEKAALDRESQMKAMKETV 210
AQQ+ DLE++L A+ +L+ + E+++K +++ +
Sbjct: 949 ---AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
Score = 36.2 bits (82), Expect = 0.044
Identities = 31/186 (16%), Positives = 84/186 (45%), Gaps = 10/186 (5%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
ELE + ++ ++ + K ++ + L++LK + + EL K+ +
Sbjct: 1115 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNK 145
E+ L++AL E+ H+A + ++ ++ ++ + +L + + K + +K
Sbjct: 1175 EVTVLKKALD-------EETRSHEAQVQEMR---QKHAQAVEELTEQLEQFKRAKANLDK 1224
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKA 205
+E+ + +L+ L K+++ K ++L Q+L ++ E+A + ++
Sbjct: 1225 NKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1284
Query: 206 MKETVQ 211
++ V+
Sbjct: 1285 LQNEVE 1290
Score = 34.3 bits (77), Expect = 0.17
Identities = 42/188 (22%), Positives = 78/188 (41%), Gaps = 16/188 (8%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQS-LKNDEQSAKTDVQKLLELGQKQ 83
EE +QL+ E T L K K L+ LK+ E A + + K
Sbjct: 1588 EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--------KG 1639
Query: 84 REEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSG 143
REE LQ Q+K+ + E +A+ + + + K + L+ + L+ L +
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
Query: 144 NKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM 203
+ E +++ +L G+ L + ++L E ++A + ELE + + M
Sbjct: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRL---EARIAQLEEELE----EEQGNM 1752
Query: 204 KAMKETVQ 211
+AM + V+
Sbjct: 1753 EAMSDRVR 1760
Score = 32.7 bits (73), Expect = 0.49
Identities = 27/115 (23%), Positives = 60/115 (52%), Gaps = 11/115 (9%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
+LE+Q+++ +E+ TK+ ++ D + LK + D +K+ E ++Q E
Sbjct: 1825 QLEEQVEQEAREKQAA----TKSLKQKD------KKLKEILLQVE-DERKMAEQYKEQAE 1873
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKL 140
+ + + L+ QL+E E++++ A L+ E++ ++ + E +LK+KL
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 52.4 bits (124), Expect = 6e-07
Identities = 60/277 (21%), Positives = 119/277 (42%), Gaps = 31/277 (11%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
++L L + +E+S +L + + +E +G +V + T+ Q L +K
Sbjct: 76 KKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLN 135
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
L++ + KE E+ KH + L ++ SK I+ L++E+KSLK+++
Sbjct: 136 RSNSELEDEILCLEKELKEEKSKHSEQ-DELMADI---SKRIQSLEDESKSLKSQVAEAK 191
Query: 145 KLCGIHAEESKKIQAQLK-------ELRYGKKDLLFKA----QQLTDLEQKLAV---AKN 190
I ++++ +K +L+ +K LL +A +Q+++L ++ +K
Sbjct: 192 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 251
Query: 191 ELEKAALDRESQMKAMKETV------QLCLTSVFRDQPPPPLSLITSNPTRMLL--PPRN 242
E+ D+ES +K + E + L D L + + + L PP+
Sbjct: 252 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 311
Query: 243 IASKLPDAAAKSKPQQSASGNN-----ESSQVESTKE 274
KL AA + ++ G + S+V+ TKE
Sbjct: 312 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKE 348
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/166 (21%), Positives = 70/166 (42%), Gaps = 7/166 (4%)
Query: 30 QLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKS 89
QL EV K + + + E ++ +N+ Q + ++ + EL Q+ ++
Sbjct: 339 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 398
Query: 90 LQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENK----SLKNKLLSGNK 145
+N E EK K I+ E+E K +DL+ E + S + +++S K
Sbjct: 399 KLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEK 458
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNE 191
+ ++ + L +LR K+ Q+LT+ E K + + +
Sbjct: 459 KAHDNWLAARNAERNLNDLR---KENAHNRQKLTETELKFELLEKD 501
Score = 34.7 bits (78), Expect = 0.13
Identities = 62/243 (25%), Positives = 110/243 (45%), Gaps = 67/243 (27%)
Query: 18 LSTRQDYEELEKQL---KEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQS-AKTDV 73
L+ +E +KQL EV+KE+ + +L K + KV+ + + ND++S KT
Sbjct: 212 LNENSQLQESQKQLLQEAEVWKEQ---VSELNKQKVTFEDSKVHAEQVLNDKESHIKTLT 268
Query: 74 QKLLE-------LGQKQRE------EMKSLQE---ALQNQLKETSEK---AEKHQATINF 114
++LL+ LG+ + EM S E L N K +K A K A++
Sbjct: 269 ERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKT 328
Query: 115 LKTE--------------VERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAE-ESKKIQA 159
L+ E E ++ I++LQ E SL+++ H E E++K+Q
Sbjct: 329 LEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSE--------NTHFENENQKLQQ 380
Query: 160 QLKELR--YGKKDL-------------LFKAQQLTDLEQKLAVAKNELE---KAALDRES 201
+LK + Y + ++ L K ++L+ +++K++ A ELE K A D E
Sbjct: 381 KLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEE 440
Query: 202 QMK 204
+++
Sbjct: 441 ELE 443
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 52.4 bits (124), Expect = 6e-07
Identities = 60/277 (21%), Positives = 119/277 (42%), Gaps = 31/277 (11%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
++L L + +E+S +L + + +E +G +V + T+ Q L +K
Sbjct: 76 KKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLN 135
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
L++ + KE E+ KH + L ++ SK I+ L++E+KSLK+++
Sbjct: 136 RSNSELEDEILCLEKELKEEKSKHSEQ-DELMADI---SKRIQSLEDESKSLKSQVAEAK 191
Query: 145 KLCGIHAEESKKIQAQLK-------ELRYGKKDLLFKA----QQLTDLEQKLAV---AKN 190
I ++++ +K +L+ +K LL +A +Q+++L ++ +K
Sbjct: 192 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 251
Query: 191 ELEKAALDRESQMKAMKETV------QLCLTSVFRDQPPPPLSLITSNPTRMLL--PPRN 242
E+ D+ES +K + E + L D L + + + L PP+
Sbjct: 252 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 311
Query: 243 IASKLPDAAAKSKPQQSASGNN-----ESSQVESTKE 274
KL AA + ++ G + S+V+ TKE
Sbjct: 312 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKE 348
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/166 (21%), Positives = 70/166 (42%), Gaps = 7/166 (4%)
Query: 30 QLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKS 89
QL EV K + + + E ++ +N+ Q + ++ + EL Q+ ++
Sbjct: 339 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 398
Query: 90 LQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENK----SLKNKLLSGNK 145
+N E EK K I+ E+E K +DL+ E + S + +++S K
Sbjct: 399 KLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEK 458
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNE 191
+ ++ + L +LR K+ Q+LT+ E K + + +
Sbjct: 459 KAHDNWLAARNAERNLNDLR---KENAHNRQKLTETELKFELLEKD 501
Score = 34.7 bits (78), Expect = 0.13
Identities = 62/243 (25%), Positives = 110/243 (45%), Gaps = 67/243 (27%)
Query: 18 LSTRQDYEELEKQL---KEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQS-AKTDV 73
L+ +E +KQL EV+KE+ + +L K + KV+ + + ND++S KT
Sbjct: 212 LNENSQLQESQKQLLQEAEVWKEQ---VSELNKQKVTFEDSKVHAEQVLNDKESHIKTLT 268
Query: 74 QKLLE-------LGQKQRE------EMKSLQE---ALQNQLKETSEK---AEKHQATINF 114
++LL+ LG+ + EM S E L N K +K A K A++
Sbjct: 269 ERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKT 328
Query: 115 LKTE--------------VERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAE-ESKKIQA 159
L+ E E ++ I++LQ E SL+++ H E E++K+Q
Sbjct: 329 LEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSE--------NTHFENENQKLQQ 380
Query: 160 QLKELR--YGKKDL-------------LFKAQQLTDLEQKLAVAKNELE---KAALDRES 201
+LK + Y + ++ L K ++L+ +++K++ A ELE K A D E
Sbjct: 381 KLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEE 440
Query: 202 QMK 204
+++
Sbjct: 441 ELE 443
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 52.4 bits (124), Expect = 6e-07
Identities = 60/277 (21%), Positives = 119/277 (42%), Gaps = 31/277 (11%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
++L L + +E+S +L + + +E +G +V + T+ Q L +K
Sbjct: 47 KKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLN 106
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
L++ + KE E+ KH + L ++ SK I+ L++E+KSLK+++
Sbjct: 107 RSNSELEDEILCLEKELKEEKSKHSEQ-DELMADI---SKRIQSLEDESKSLKSQVAEAK 162
Query: 145 KLCGIHAEESKKIQAQLK-------ELRYGKKDLLFKA----QQLTDLEQKLAV---AKN 190
I ++++ +K +L+ +K LL +A +Q+++L ++ +K
Sbjct: 163 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 222
Query: 191 ELEKAALDRESQMKAMKETV------QLCLTSVFRDQPPPPLSLITSNPTRMLL--PPRN 242
E+ D+ES +K + E + L D L + + + L PP+
Sbjct: 223 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 282
Query: 243 IASKLPDAAAKSKPQQSASGNN-----ESSQVESTKE 274
KL AA + ++ G + S+V+ TKE
Sbjct: 283 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKE 319
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/166 (21%), Positives = 70/166 (42%), Gaps = 7/166 (4%)
Query: 30 QLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKS 89
QL EV K + + + E ++ +N+ Q + ++ + EL Q+ ++
Sbjct: 310 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 369
Query: 90 LQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENK----SLKNKLLSGNK 145
+N E EK K I+ E+E K +DL+ E + S + +++S K
Sbjct: 370 KLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEK 429
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNE 191
+ ++ + L +LR K+ Q+LT+ E K + + +
Sbjct: 430 KAHDNWLAARNAERNLNDLR---KENAHNRQKLTETELKFELLEKD 472
Score = 34.7 bits (78), Expect = 0.13
Identities = 62/243 (25%), Positives = 110/243 (45%), Gaps = 67/243 (27%)
Query: 18 LSTRQDYEELEKQL---KEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQS-AKTDV 73
L+ +E +KQL EV+KE+ + +L K + KV+ + + ND++S KT
Sbjct: 183 LNENSQLQESQKQLLQEAEVWKEQ---VSELNKQKVTFEDSKVHAEQVLNDKESHIKTLT 239
Query: 74 QKLLE-------LGQKQRE------EMKSLQE---ALQNQLKETSEK---AEKHQATINF 114
++LL+ LG+ + EM S E L N K +K A K A++
Sbjct: 240 ERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKT 299
Query: 115 LKTE--------------VERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAE-ESKKIQA 159
L+ E E ++ I++LQ E SL+++ H E E++K+Q
Sbjct: 300 LEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSE--------NTHFENENQKLQQ 351
Query: 160 QLKELR--YGKKDL-------------LFKAQQLTDLEQKLAVAKNELE---KAALDRES 201
+LK + Y + ++ L K ++L+ +++K++ A ELE K A D E
Sbjct: 352 KLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEE 411
Query: 202 QMK 204
+++
Sbjct: 412 ELE 414
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 52.4 bits (124), Expect = 6e-07
Identities = 60/277 (21%), Positives = 119/277 (42%), Gaps = 31/277 (11%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
++L L + +E+S +L + + +E +G +V + T+ Q L +K
Sbjct: 64 KKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLN 123
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGN 144
L++ + KE E+ KH + L ++ SK I+ L++E+KSLK+++
Sbjct: 124 RSNSELEDEILCLEKELKEEKSKHSEQ-DELMADI---SKRIQSLEDESKSLKSQVAEAK 179
Query: 145 KLCGIHAEESKKIQAQLK-------ELRYGKKDLLFKA----QQLTDLEQKLAV---AKN 190
I ++++ +K +L+ +K LL +A +Q+++L ++ +K
Sbjct: 180 MTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKV 239
Query: 191 ELEKAALDRESQMKAMKETV------QLCLTSVFRDQPPPPLSLITSNPTRMLL--PPRN 242
E+ D+ES +K + E + L D L + + + L PP+
Sbjct: 240 HAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKG 299
Query: 243 IASKLPDAAAKSKPQQSASGNN-----ESSQVESTKE 274
KL AA + ++ G + S+V+ TKE
Sbjct: 300 ALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKE 336
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/166 (21%), Positives = 70/166 (42%), Gaps = 7/166 (4%)
Query: 30 QLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKS 89
QL EV K + + + E ++ +N+ Q + ++ + EL Q+ ++
Sbjct: 327 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHR 386
Query: 90 LQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENK----SLKNKLLSGNK 145
+N E EK K I+ E+E K +DL+ E + S + +++S K
Sbjct: 387 KLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEK 446
Query: 146 LCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNE 191
+ ++ + L +LR K+ Q+LT+ E K + + +
Sbjct: 447 KAHDNWLAARNAERNLNDLR---KENAHNRQKLTETELKFELLEKD 489
Score = 34.7 bits (78), Expect = 0.13
Identities = 62/243 (25%), Positives = 110/243 (45%), Gaps = 67/243 (27%)
Query: 18 LSTRQDYEELEKQL---KEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQS-AKTDV 73
L+ +E +KQL EV+KE+ + +L K + KV+ + + ND++S KT
Sbjct: 200 LNENSQLQESQKQLLQEAEVWKEQ---VSELNKQKVTFEDSKVHAEQVLNDKESHIKTLT 256
Query: 74 QKLLE-------LGQKQRE------EMKSLQE---ALQNQLKETSEK---AEKHQATINF 114
++LL+ LG+ + EM S E L N K +K A K A++
Sbjct: 257 ERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKT 316
Query: 115 LKTE--------------VERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAE-ESKKIQA 159
L+ E E ++ I++LQ E SL+++ H E E++K+Q
Sbjct: 317 LEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSE--------NTHFENENQKLQQ 368
Query: 160 QLKELR--YGKKDL-------------LFKAQQLTDLEQKLAVAKNELE---KAALDRES 201
+LK + Y + ++ L K ++L+ +++K++ A ELE K A D E
Sbjct: 369 KLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEE 428
Query: 202 QMK 204
+++
Sbjct: 429 ELE 431
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 52.0 bits (123), Expect = 8e-07
Identities = 45/163 (27%), Positives = 84/163 (51%), Gaps = 13/163 (7%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTS---RELDGIKVNLQSLKNDEQSAKTDVQKLLELGQ 81
EE EK+ + K+ +++ QL T +E K+NL S + K +Q+ E +
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEE 1356
Query: 82 KQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLL 141
+ R+ ++ ALQ+QL +T +K + TI L+ E K K+++D + ++ L+ K L
Sbjct: 1357 EARKNLEKQVLALQSQLADTKKKVDDDLGTIESLE---EAKKKLLKDAEALSQRLEEKAL 1413
Query: 142 SGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQK 184
+ +KL + ++Q +L +L DL + Q ++LE+K
Sbjct: 1414 AYDKL----EKTKNRLQQELDDLTV---DLDHQRQVASNLEKK 1449
Score = 48.5 bits (114), Expect = 9e-06
Identities = 54/210 (25%), Positives = 95/210 (45%), Gaps = 25/210 (11%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLL-EL 79
R + E EK+ K + R+ L + + E + L++ D S+K DV K + EL
Sbjct: 1473 RAEAEAREKETKALSLARA--LEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHEL 1530
Query: 80 GQKQR------EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
+ +R EEM++ E L+++L+ T + + + + +K + ER RD QNE
Sbjct: 1531 EKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER-DLQTRDEQNEE 1589
Query: 134 K---------SLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKA-----QQLT 179
K L+ +L K + KK++ LK+L + + KA +QL
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE-AQIEAANKARDEVIKQLR 1648
Query: 180 DLEQKLAVAKNELEKAALDRESQMKAMKET 209
L+ ++ + ELE+A R+ KE+
Sbjct: 1649 KLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Score = 44.7 bits (104), Expect = 1e-04
Identities = 54/188 (28%), Positives = 88/188 (46%), Gaps = 17/188 (9%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
R E + L+E K+ ++L K R+LDG +LQ + E A+ D KL +L
Sbjct: 1029 RNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD-QIAELQAQIDELKL-QLA 1086
Query: 81 QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKL 140
+K+ E LQ AL ET K N LK E +++ I +LQ + +S K
Sbjct: 1087 KKEEE----LQGALARGDDETLHKN-------NALKVVRELQAQ-IAELQEDFESEK--- 1131
Query: 141 LSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRE 200
S NK + S++++A EL + + T EQ++A K LE+ + E
Sbjct: 1132 ASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHE 1191
Query: 201 SQMKAMKE 208
+Q++ M++
Sbjct: 1192 AQIQDMRQ 1199
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/187 (22%), Positives = 88/187 (47%), Gaps = 17/187 (9%)
Query: 18 LSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIK----VNLQSLKNDEQSAKTDV 73
L TR + E +K+L +++Q+ + EL+ + + + S K E K D+
Sbjct: 1580 LQTRDEQNEEKKRL---------LIKQVRELEAELEDERKQRALAVASKKKMEIDLK-DL 1629
Query: 74 QKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN 133
+ +E K R+E+ LQ Q+K+ + E+ +A+ + + + + K ++ L+ E
Sbjct: 1630 EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEI 1689
Query: 134 KSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELE 193
L+ +L S + +E ++ ++ GK LL + ++ LE ++A + ELE
Sbjct: 1690 LQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRR---LEARIAQLEEELE 1746
Query: 194 KAALDRE 200
+ + E
Sbjct: 1747 EEQSNME 1753
Score = 43.5 bits (101), Expect = 3e-04
Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 25/214 (11%)
Query: 19 STRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL-- 76
S ++ EE E+ K + K+ + QL T +++D ++SL+ ++ D + L
Sbjct: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQ 1406
Query: 77 -LELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKS 135
LE ++++ + LQ +L + + + HQ + + +E+K K L E KS
Sbjct: 1407 RLEEKALAYDKLEKTKNRLQQELDDLTVDLD-HQRQV---ASNLEKKQKKFDQLLAEEKS 1462
Query: 136 L------------------KNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQ 177
+ + K LS + E ++ + Q K+LR +DL+
Sbjct: 1463 ISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDD 1522
Query: 178 LTDLEQKLAVAKNELEKAALDRESQMKAMKETVQ 211
+ +L +K LE+ + +Q++ +++ +Q
Sbjct: 1523 VGKNVHELEKSKRALEQQVEEMRTQLEELEDELQ 1556
Score = 43.1 bits (100), Expect = 4e-04
Identities = 41/196 (20%), Positives = 90/196 (45%), Gaps = 19/196 (9%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
EL+ Q+ E+ ++ + K ++ + L++LK + + EL K+ +
Sbjct: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174
Query: 86 EM----KSLQEALQNQLKETSEKAEKHQATINFLKTEVERK-------SKMIRDLQNENK 134
E+ K+L+E +N + + ++H + L ++E+ K + L+ +NK
Sbjct: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
Query: 135 SLKNKLLSGNKLCGIHAEESKKIQAQLKEL--RYGKKDLLFKAQQLTDLEQKLAVAKNEL 192
L ++ ++ + KK+ AQ++EL + + D L +L +K + +NEL
Sbjct: 1235 ELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRL-----RVELAEKASKLQNEL 1289
Query: 193 EK-AALDRESQMKAMK 207
+ + L E++ K +K
Sbjct: 1290 DNVSTLLEEAEKKGIK 1305
Score = 43.1 bits (100), Expect = 4e-04
Identities = 45/237 (18%), Positives = 107/237 (45%), Gaps = 20/237 (8%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQRE 85
+LE++L+E + + KT+ ++D + L + ++ Q + Q+L ++ +
Sbjct: 1740 QLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKA 1799
Query: 86 EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERK-------SKMIRDLQNENKSLKN 138
+++ L+ A++++ K T E A I L+ ++E++ +K++R + + K +
Sbjct: 1800 KLQELEGAVKSKFKATISALE---AKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856
Query: 139 KLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALD 198
++ + + E+ +K A++K+L+ +QL + E++ A K +
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLK----------RQLEEAEEEATRANASRRKLQRE 1906
Query: 199 RESQMKAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASKLPDAAAKSK 255
+ +A + + T R + P+S +S R L + +L D +SK
Sbjct: 1907 LDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDDDTESK 1963
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/192 (21%), Positives = 96/192 (50%), Gaps = 20/192 (10%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
E+L+ + E+F E + +L +EL+ I +L+S +E+ ++ Q ++
Sbjct: 894 EQLQAET-ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERN-------QILQNEK 945
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNEN-KSLKNKLLSG 143
++M++ + L+ QL E +K Q + ++++ + I L+++N K +K K L
Sbjct: 946 KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
Query: 144 NKL--CGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKL---AVAKNELEKAALD 198
+++ C E ++ L ++R K++++ ++DLE++L + ELEKA
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIR-NKQEVM-----ISDLEERLKKEEKTRQELEKAKRK 1059
Query: 199 RESQMKAMKETV 210
+ + +++ +
Sbjct: 1060 LDGETTDLQDQI 1071
Score = 38.1 bits (87), Expect = 0.012
Identities = 42/221 (19%), Positives = 94/221 (42%), Gaps = 26/221 (11%)
Query: 13 LPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTD 72
L A + + + +E+ KQL+++ + R+L + D I + + +S + +
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688
Query: 73 VQKLL-ELGQKQREEMKSLQE-----------------------ALQNQLKETSEKAEKH 108
+ +L EL +R + QE L+ ++ + E+ E+
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 109 QATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGK 168
Q+ + L + + + L E + ++ + ++K+++A+L+EL G
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE-GA 1807
Query: 169 KDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKET 209
FKA ++ LE K+ + +LE+ A +R + K ++ T
Sbjct: 1808 VKSKFKA-TISALEAKIGQLEEQLEQEAKERAAANKLVRRT 1847
>gi|109134347 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 52.0 bits (123), Expect = 8e-07
Identities = 45/201 (22%), Positives = 92/201 (45%), Gaps = 32/201 (15%)
Query: 22 QDYEELEKQLKEV-----FKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL 76
+D EEL QL V K + R+ ++L G++ + LK ++++++ V+
Sbjct: 189 EDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVENA 248
Query: 77 LELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSL 136
+ +Q EM++ +L+ AEK A + ER K ++ +N L
Sbjct: 249 QRIQVRQLAEMQATVRSLE---------AEKQSANL-----RAERLEKELQSSSEQNTFL 294
Query: 137 KNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAA 196
NKL + E + +++KEL++ K ++TD++ + A AK+ELE+
Sbjct: 295 INKLHKAER-------EINTLSSKVKELKHSNK------LEITDIKLETARAKSELERER 341
Query: 197 LDRESQMKAMKETVQLCLTSV 217
+S++ ++ ++ +V
Sbjct: 342 NKIQSELDGLQSDNEILKAAV 362
Score = 46.2 bits (108), Expect = 4e-05
Identities = 54/223 (24%), Positives = 106/223 (47%), Gaps = 29/223 (13%)
Query: 17 VLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDE----QSAKTD 72
VL +D EL ++++ +E L L EL+ +L+ +K + QS K
Sbjct: 367 VLLVEKD-RELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQ 425
Query: 73 VQKLLELGQKQ----REEMKSLQEALQNQLKETSEKAEKHQ-------ATINFLKTEVER 121
++ L Q R+E++S++ LQ Q+ T E AEK + I+ L+ +V
Sbjct: 426 YEEKLRASQMAEEITRKELQSVRLKLQQQIV-TIENAEKEKNENSDLKQQISSLQIQVTS 484
Query: 122 KSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKA-----Q 176
++ DL N N+ LK + + C +++K Q + ++ K+ + +
Sbjct: 485 LAQSENDLLNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHE 544
Query: 177 QLTDLEQKLAVAKNELEKAALDR-------ESQMKAMKETVQL 212
++TD E+K AK +L++AA+ + E+++K ++E V++
Sbjct: 545 RITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEV 587
Score = 45.8 bits (107), Expect = 6e-05
Identities = 47/215 (21%), Positives = 103/215 (47%), Gaps = 21/215 (9%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG---- 80
E LEK+L+ ++ + ++ +L K RE++ + ++ LK+ + TD++ LE
Sbjct: 278 ERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIK--LETARAKS 335
Query: 81 --QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRD--------LQ 130
+++R +++S + LQ+ + E H+ + E+ RK + ++ LQ
Sbjct: 336 ELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQ 395
Query: 131 NENKSLKNKLLSGNKLCGIHA--EESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVA 188
+E L+N+L K+ H +S+K Q + ++LR + ++L + KL
Sbjct: 396 DEKLELENRLADLEKMKVEHDVWRQSEKDQYE-EKLRASQMAEEITRKELQSVRLKLQQQ 454
Query: 189 KNELEKAALDR--ESQMKAMKETVQLCLTSVFRDQ 221
+E A ++ S +K ++Q+ +TS+ + +
Sbjct: 455 IVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSE 489
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/213 (20%), Positives = 96/213 (45%), Gaps = 30/213 (14%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
+ ++ +L+ +LK +F E+ T +L EL G L D + K + +L
Sbjct: 60 QNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRG---ELVEKTKDLEEMKLQILTPQKLE 116
Query: 81 QKQREEMKSLQEALQNQLKETSEKAEKHQATIN-------FLKTEVERKSK--------- 124
+ + + L+ ++ + + E+ EK++A N FLK+E E + +
Sbjct: 117 LLRAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARILDEG 176
Query: 125 ------MIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQL 178
I L+ + + L+N+LL+ + ++SK+++ +E Y + L ++
Sbjct: 177 KIKYESEIARLEEDKEELRNQLLNVDL-----TKDSKRVEQLAREKVYLCQKLKGLEAEV 231
Query: 179 TDLEQKLAVAKNELEKAALDRESQMKAMKETVQ 211
+L+ + ++ ++E A + Q+ M+ TV+
Sbjct: 232 AELKAEKENSEAQVENAQRIQVRQLAEMQATVR 264
Score = 34.3 bits (77), Expect = 0.17
Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 14/111 (12%)
Query: 91 QEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIH 150
Q Q L + + E H+A LK E R LQNE K L N+
Sbjct: 28 QSEFQKMLIDERLRCEHHKANYQTLKAEHTRLQNEHVKLQNELKHLFNE----------K 77
Query: 151 AEESKKIQAQLKELRYGKKDLLFKAQQLTDLE-QKLAVAKNELEKAALDRE 200
+ +K+Q L+ELR +L+ K + L +++ Q L K EL +A + +E
Sbjct: 78 QTQQEKLQLLLEELR---GELVEKTKDLEEMKLQILTPQKLELLRAQIQQE 125
Score = 32.7 bits (73), Expect = 0.49
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 18/176 (10%)
Query: 56 KVNLQSLK-------NDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKH 108
K N Q+LK N+ + +++ L Q Q+E+++ L E L+ +L E ++ E+
Sbjct: 46 KANYQTLKAEHTRLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEM 105
Query: 109 QATI------NFLKTEV--ERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQ 160
+ I L+ ++ E ++ M +N ++ ++ NKL H + + Q
Sbjct: 106 KLQILTPQKLELLRAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSEFEHQ 165
Query: 161 LKE-LRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM--KAMKETVQLC 213
+E R + + ++ LE+ +N+L L ++S+ + +E V LC
Sbjct: 166 KEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLC 221
Score = 30.4 bits (67), Expect = 2.4
Identities = 31/149 (20%), Positives = 66/149 (44%), Gaps = 24/149 (16%)
Query: 17 VLSTRQDYEELEKQLKEVFK------ERSTILRQLTKTSRELDGI--KVNLQSLKNDEQS 68
+L++ Q +E+ ++LK+ + E++ + + T +++ + K L D +
Sbjct: 492 LLNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHERITDREE 551
Query: 69 AKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVE-------- 120
++ L+ +++ KSL E N+LK EK E +A L+TE +
Sbjct: 552 KYNQAKEKLQRAAIAQKKRKSLHE---NKLKRLQEKVEVLEAKKEELETENQVLNRQNVP 608
Query: 121 -----RKSKMIRDLQNENKSLKNKLLSGN 144
R K ++D+Q + ++ +L N
Sbjct: 609 FEDYTRLQKRLKDIQRRHNEFRSLILVPN 637
>gi|109134355 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 52.0 bits (123), Expect = 8e-07
Identities = 45/201 (22%), Positives = 92/201 (45%), Gaps = 32/201 (15%)
Query: 22 QDYEELEKQLKEV-----FKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKL 76
+D EEL QL V K + R+ ++L G++ + LK ++++++ V+
Sbjct: 189 EDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVENA 248
Query: 77 LELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSL 136
+ +Q EM++ +L+ AEK A + ER K ++ +N L
Sbjct: 249 QRIQVRQLAEMQATVRSLE---------AEKQSANL-----RAERLEKELQSSSEQNTFL 294
Query: 137 KNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAA 196
NKL + E + +++KEL++ K ++TD++ + A AK+ELE+
Sbjct: 295 INKLHKAER-------EINTLSSKVKELKHSNK------LEITDIKLETARAKSELERER 341
Query: 197 LDRESQMKAMKETVQLCLTSV 217
+S++ ++ ++ +V
Sbjct: 342 NKIQSELDGLQSDNEILKAAV 362
Score = 46.2 bits (108), Expect = 4e-05
Identities = 54/223 (24%), Positives = 106/223 (47%), Gaps = 29/223 (13%)
Query: 17 VLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDE----QSAKTD 72
VL +D EL ++++ +E L L EL+ +L+ +K + QS K
Sbjct: 367 VLLVEKD-RELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQ 425
Query: 73 VQKLLELGQKQ----REEMKSLQEALQNQLKETSEKAEKHQ-------ATINFLKTEVER 121
++ L Q R+E++S++ LQ Q+ T E AEK + I+ L+ +V
Sbjct: 426 YEEKLRASQMAEEITRKELQSVRLKLQQQIV-TIENAEKEKNENSDLKQQISSLQIQVTS 484
Query: 122 KSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKA-----Q 176
++ DL N N+ LK + + C +++K Q + ++ K+ + +
Sbjct: 485 LAQSENDLLNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHE 544
Query: 177 QLTDLEQKLAVAKNELEKAALDR-------ESQMKAMKETVQL 212
++TD E+K AK +L++AA+ + E+++K ++E V++
Sbjct: 545 RITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEV 587
Score = 45.8 bits (107), Expect = 6e-05
Identities = 47/215 (21%), Positives = 103/215 (47%), Gaps = 21/215 (9%)
Query: 25 EELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG---- 80
E LEK+L+ ++ + ++ +L K RE++ + ++ LK+ + TD++ LE
Sbjct: 278 ERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIK--LETARAKS 335
Query: 81 --QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRD--------LQ 130
+++R +++S + LQ+ + E H+ + E+ RK + ++ LQ
Sbjct: 336 ELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQ 395
Query: 131 NENKSLKNKLLSGNKLCGIHA--EESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVA 188
+E L+N+L K+ H +S+K Q + ++LR + ++L + KL
Sbjct: 396 DEKLELENRLADLEKMKVEHDVWRQSEKDQYE-EKLRASQMAEEITRKELQSVRLKLQQQ 454
Query: 189 KNELEKAALDR--ESQMKAMKETVQLCLTSVFRDQ 221
+E A ++ S +K ++Q+ +TS+ + +
Sbjct: 455 IVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSE 489
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/213 (20%), Positives = 96/213 (45%), Gaps = 30/213 (14%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
+ ++ +L+ +LK +F E+ T +L EL G L D + K + +L
Sbjct: 60 QNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRG---ELVEKTKDLEEMKLQILTPQKLE 116
Query: 81 QKQREEMKSLQEALQNQLKETSEKAEKHQATIN-------FLKTEVERKSK--------- 124
+ + + L+ ++ + + E+ EK++A N FLK+E E + +
Sbjct: 117 LLRAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARILDEG 176
Query: 125 ------MIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQL 178
I L+ + + L+N+LL+ + ++SK+++ +E Y + L ++
Sbjct: 177 KIKYESEIARLEEDKEELRNQLLNVDL-----TKDSKRVEQLAREKVYLCQKLKGLEAEV 231
Query: 179 TDLEQKLAVAKNELEKAALDRESQMKAMKETVQ 211
+L+ + ++ ++E A + Q+ M+ TV+
Sbjct: 232 AELKAEKENSEAQVENAQRIQVRQLAEMQATVR 264
Score = 34.3 bits (77), Expect = 0.17
Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 14/111 (12%)
Query: 91 QEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIH 150
Q Q L + + E H+A LK E R LQNE K L N+
Sbjct: 28 QSEFQKMLIDERLRCEHHKANYQTLKAEHTRLQNEHVKLQNELKHLFNE----------K 77
Query: 151 AEESKKIQAQLKELRYGKKDLLFKAQQLTDLE-QKLAVAKNELEKAALDRE 200
+ +K+Q L+ELR +L+ K + L +++ Q L K EL +A + +E
Sbjct: 78 QTQQEKLQLLLEELR---GELVEKTKDLEEMKLQILTPQKLELLRAQIQQE 125
Score = 32.7 bits (73), Expect = 0.49
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 18/176 (10%)
Query: 56 KVNLQSLK-------NDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKH 108
K N Q+LK N+ + +++ L Q Q+E+++ L E L+ +L E ++ E+
Sbjct: 46 KANYQTLKAEHTRLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEM 105
Query: 109 QATI------NFLKTEV--ERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQ 160
+ I L+ ++ E ++ M +N ++ ++ NKL H + + Q
Sbjct: 106 KLQILTPQKLELLRAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSEFEHQ 165
Query: 161 LKE-LRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQM--KAMKETVQLC 213
+E R + + ++ LE+ +N+L L ++S+ + +E V LC
Sbjct: 166 KEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLC 221
Score = 30.4 bits (67), Expect = 2.4
Identities = 31/149 (20%), Positives = 66/149 (44%), Gaps = 24/149 (16%)
Query: 17 VLSTRQDYEELEKQLKEVFK------ERSTILRQLTKTSRELDGI--KVNLQSLKNDEQS 68
+L++ Q +E+ ++LK+ + E++ + + T +++ + K L D +
Sbjct: 492 LLNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHERITDREE 551
Query: 69 AKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVE-------- 120
++ L+ +++ KSL E N+LK EK E +A L+TE +
Sbjct: 552 KYNQAKEKLQRAAIAQKKRKSLHE---NKLKRLQEKVEVLEAKKEELETENQVLNRQNVP 608
Query: 121 -----RKSKMIRDLQNENKSLKNKLLSGN 144
R K ++D+Q + ++ +L N
Sbjct: 609 FEDYTRLQKRLKDIQRRHNEFRSLILVPN 637
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/192 (21%), Positives = 92/192 (47%), Gaps = 12/192 (6%)
Query: 26 ELEKQLKEVFKERSTILRQLTKTSRELDG-IKVNLQSLKNDEQSAKTDVQKLLELGQKQR 84
E E +E+ ER+ + QL + EL ++ + L + + + + + L L + ++
Sbjct: 1001 EKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEK 1060
Query: 85 EEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLS-- 142
++ SL+E+ + L E ATI+ E+ER+ + + Q +++S N L S
Sbjct: 1061 QQALSLKESEKTALSEKLMGTRHSLATISL---EMERQKRDAQSRQEQDRSTVNALTSEL 1117
Query: 143 ------GNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAA 196
+ HA+E +++Q Q ++L + L +A++L + L A++ L +
Sbjct: 1118 RDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRREL 1177
Query: 197 LDRESQMKAMKE 208
L+ + +++ +E
Sbjct: 1178 LEAQRKLRESQE 1189
Score = 45.4 bits (106), Expect = 7e-05
Identities = 38/175 (21%), Positives = 82/175 (46%), Gaps = 7/175 (4%)
Query: 37 ERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQN 96
E++ + LTK +++++ L+ +E S + + KL L + ++ L L
Sbjct: 702 EKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNR-LVA 760
Query: 97 QLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKK 156
QL+E + Q T + + + +L+ E + + L G+ A+E+
Sbjct: 761 QLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGL-EGSLRVAEQAQEA-- 817
Query: 157 IQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQ 211
++ QL LR+ + L +QL L ++L+ + ELE+A + + Q++A++ +
Sbjct: 818 LEQQLPTLRHERSQL---QEQLAQLSRQLSGREQELEQARREAQRQVEALERAAR 869
Score = 42.7 bits (99), Expect = 5e-04
Identities = 45/208 (21%), Positives = 100/208 (48%), Gaps = 30/208 (14%)
Query: 22 QDYEELEKQLKEVFKERSTILRQLTKTSREL-------DGIKVNL----QSLKNDEQSAK 70
Q+ L++Q +++ K+R + LR+ + +L DG++ L + L+ ++ +
Sbjct: 1133 QEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGRE 1192
Query: 71 TDVQKLLEL------GQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSK 124
Q+ EL G K+RE ++ E L++ +K KAE + ++ + E+K
Sbjct: 1193 VQRQEAGELRRSLGEGAKEREALRRSNEELRSAVK----KAESERISLKLANEDKEQKLA 1248
Query: 125 MIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQK 184
++ E ++ K +G G+ E +++A+ +EL+ ++ + + T L ++
Sbjct: 1249 LL----EEARTAVGK-EAGELRTGLQEVERSRLEAR-RELQELRRQMKMLDSENTRLGRE 1302
Query: 185 LAVAKNELEKAALDRESQMKAMKETVQL 212
LA + L AL ++ ++ +ET+ L
Sbjct: 1303 LAELQGRL---ALGERAEKESRRETLGL 1327
Score = 42.4 bits (98), Expect = 6e-04
Identities = 42/214 (19%), Positives = 99/214 (46%), Gaps = 11/214 (5%)
Query: 2 KFSPAHYLLPLLPALVLSTRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQS 61
++ + LL L + + + LE+QL+ + + ++ RE+ ++ +
Sbjct: 541 RYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANEL 600
Query: 62 LKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQNQLKETSEKAEKHQATI----NFLKT 117
L ++ + +Q + ++ R+E + LQ A Q +L+ ++ E+ Q ++
Sbjct: 601 LSREKSNLAHSLQVAQQQAEELRQEREKLQ-AAQEELRRQRDRLEEEQEDAVQDGARVRR 659
Query: 118 EVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQ 177
E+ER + + L+ + L +L+ + + +QA+ E+ + L KA +
Sbjct: 660 ELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEV----AEALTKA-E 714
Query: 178 LTDLEQKLAVAKNELEKAAL-DRESQMKAMKETV 210
+E +L++ K E+A+L D S++ A+ E++
Sbjct: 715 AGRVELELSMTKLRAEEASLQDSLSKLSALNESL 748
Score = 42.0 bits (97), Expect = 8e-04
Identities = 46/183 (25%), Positives = 82/183 (44%), Gaps = 32/183 (17%)
Query: 22 QDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQ 81
Q E LE+QL + ERS + QL + SR+L G + EL Q
Sbjct: 813 QAQEALEQQLPTLRHERSQLQEQLAQLSRQLSG--------------------REQELEQ 852
Query: 82 KQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRD----LQNENKSLK 137
+RE + + EAL+ +E A++H A + ER+ + + + L+ E ++L+
Sbjct: 853 ARREAQRQV-EALERAAREKEALAKEH-AGLAVQLVAAEREGRTLSEEATRLRLEKEALE 910
Query: 138 NKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAAL 197
L + ++++A+ + L K+ L +L L Q++ + EKA+L
Sbjct: 911 GSLFEVQRQLAQLEARREQLEAEGQALLLAKETL---TGELAGLRQQIIATQ---EKASL 964
Query: 198 DRE 200
D+E
Sbjct: 965 DKE 967
Score = 40.8 bits (94), Expect = 0.002
Identities = 37/192 (19%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
R+ + LE++ ++ ++ + + R+L ++ R+L+ ++ L + +V++ L
Sbjct: 637 RRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKE----LVEVREALSRA 692
Query: 81 QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRD----LQNENKSL 136
QR+ + +A + ++ E KAE + + T++ + ++D L N+SL
Sbjct: 693 TLQRDML----QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESL 748
Query: 137 KNKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAA 196
L N+L EE +Q + ++ + ++L +L + VA+ LE +
Sbjct: 749 AQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSL 808
Query: 197 LDRESQMKAMKE 208
E +A+++
Sbjct: 809 RVAEQAQEALEQ 820
Score = 38.9 bits (89), Expect = 0.007
Identities = 45/184 (24%), Positives = 80/184 (43%), Gaps = 29/184 (15%)
Query: 37 ERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELGQKQREEMKSLQEALQN 96
++ + ++L + RE SL+ + + D+Q+L + E+++ + LQ+
Sbjct: 965 DKELMAQKLVQAEREAQA------SLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Query: 97 QLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHAEESKK 156
QL+ E+ + L+ E E S+ I LQ E G+ ES+K
Sbjct: 1019 QLQREQEE------LLARLEAEKEELSEEIAALQQERDE------------GLLLAESEK 1060
Query: 157 IQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRESQMKAMKETVQLCLTS 216
QA L+ +K L +++L LA E+E+ D +S+ + + TV LTS
Sbjct: 1061 QQA--LSLKESEKTAL--SEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVN-ALTS 1115
Query: 217 VFRD 220
RD
Sbjct: 1116 ELRD 1119
Score = 35.4 bits (80), Expect = 0.076
Identities = 41/187 (21%), Positives = 85/187 (45%), Gaps = 14/187 (7%)
Query: 21 RQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLELG 80
R+ L +Q++ + E + + Q + +L ++ L+ + E +A VQKL +
Sbjct: 1781 RKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDER 1840
Query: 81 QKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKL 140
+ +E + SLQ AL QL+ +EK E ++ + K V + + +K + KL
Sbjct: 1841 RLLQERLGSLQRALA-QLE--AEKREVERSALRLEKDRVALRRTL-------DKVEREKL 1890
Query: 141 LSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDRE 200
S + AE+ + + L + +L +Q+ LE ++ V + A L+ +
Sbjct: 1891 RSHEDTVRLSAEKGRLD----RTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVD 1946
Query: 201 SQMKAMK 207
+Q + ++
Sbjct: 1947 AQQQQLE 1953
Score = 33.5 bits (75), Expect = 0.29
Identities = 40/196 (20%), Positives = 90/196 (45%), Gaps = 19/196 (9%)
Query: 19 STRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLE 78
+ R E ++L+ +ER + Q + +R+ L ++ + SA + ++L +
Sbjct: 1506 AVRGALREFLQELRSAQRERDELRTQTSALNRQ-------LAEMEAERDSATSRARQLQK 1558
Query: 79 LGQKQREEMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKN 138
+ E +S+ L E + + E + + + +++ + + R LQ L+
Sbjct: 1559 AVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELR- 1617
Query: 139 KLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLT-DLEQKLAVAKNELEKAAL 197
S K+ + A E+ K++ + L K++L ++ T LE + + EL+++ L
Sbjct: 1618 --ASQEKISKMKANET-KLEGDKRRL----KEVLDASESRTVKLELQRRSLEGELQRSRL 1670
Query: 198 ---DRESQMKAMKETV 210
DRE+Q +A+++ V
Sbjct: 1671 GLSDREAQAQALQDRV 1686
Score = 32.7 bits (73), Expect = 0.49
Identities = 65/295 (22%), Positives = 120/295 (40%), Gaps = 38/295 (12%)
Query: 19 STRQDYEELEKQLKEVFKERSTILRQLTKTSRELDGIKVNLQSLKNDEQSAKTDVQKLLE 78
STR L+K L +R + +L + L + SL Q+ + +V L E
Sbjct: 1744 STRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADL-E 1802
Query: 79 LGQKQRE-EMKSLQEALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLK 137
L + + E +++ L+E L+ ++ E A +N ++ LQ+E + L+
Sbjct: 1803 LQRVEAEGQLQQLREVLR-------QRQEGEAAALN-----------TVQKLQDERRLLQ 1844
Query: 138 NKLLSGNKLCGIHAEESKKIQAQLKELRYGKKDLLFKAQQLTDLEQ----------KLAV 187
+L G+ + E++K + + LR +KD + + L +E+ +L+
Sbjct: 1845 ERL--GSLQRALAQLEAEKREVERSALRL-EKDRVALRRTLDKVEREKLRSHEDTVRLSA 1901
Query: 188 AKNELEKAALDRESQM-KAMKETVQLCLTSVFRDQPPPPLSLITSNPTRMLLPPRNIASK 246
K L++ E ++ +A ++ QL V +Q P L + L + + +
Sbjct: 1902 EKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEV-ER 1960
Query: 247 LPDAAAKSKPQQSASGNNESSQVESTKEGNPSTTACDSQDEGRPCSMKHKESPPS 301
L A A+++ A +V +E ST Q E R S SPPS
Sbjct: 1961 LRSAQAQTERTLEARERAHRQRVRGLEE-QVSTLKGQLQQELRRSSAPF--SPPS 2012
Score = 31.6 bits (70), Expect = 1.1
Identities = 27/126 (21%), Positives = 63/126 (50%), Gaps = 14/126 (11%)
Query: 92 EALQNQLKETSEKAEKHQATINFLKTEVERKSKMIRDLQNENKSLKNKLLSGNKLCGIHA 151
EA++ L+E ++ Q + L+T+ ++ + +++ E S ++ K +
Sbjct: 1505 EAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVA-ES 1563
Query: 152 EESKK--------IQAQL----KELRYGKKDLLFKAQQLTDLEQKLAVAKNELEKAALDR 199
EE+++ +QA+L + +R +++ Q+ LE+ L ++EL +A+ ++
Sbjct: 1564 EEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESEL-RASQEK 1622
Query: 200 ESQMKA 205
S+MKA
Sbjct: 1623 ISKMKA 1628
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.123 0.329
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,096,273
Number of Sequences: 37866
Number of extensions: 616331
Number of successful extensions: 7957
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 350
Number of HSP's successfully gapped in prelim test: 841
Number of HSP's that attempted gapping in prelim test: 4358
Number of HSP's gapped (non-prelim): 3384
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.