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Search of human proteins with 13518026
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 721 0.0
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 639 0.0
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 639 0.0
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 639 0.0
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 639 0.0
gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo ... 373 e-103
gi|239758027 PREDICTED: similar to LIM and senescent cell antige... 208 5e-54
gi|170932518 paxillin isoform 3 [Homo sapiens] 149 4e-36
gi|170932516 paxillin isoform 2 [Homo sapiens] 149 4e-36
gi|170932514 paxillin isoform 1 [Homo sapiens] 149 4e-36
gi|221316659 leupaxin isoform 1 [Homo sapiens] 140 2e-33
gi|4758670 leupaxin isoform 2 [Homo sapiens] 140 2e-33
gi|109638745 transforming growth factor beta 1 induced transcrip... 135 4e-32
gi|21361591 transforming growth factor beta 1 induced transcript... 135 4e-32
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 127 1e-29
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 127 1e-29
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 127 1e-29
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 127 1e-29
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 120 2e-27
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 120 2e-27
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 120 2e-27
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 120 2e-27
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 120 2e-27
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 120 2e-27
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 120 2e-27
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 120 2e-27
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 120 2e-27
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 117 1e-26
gi|15743548 LIM and senescent cell antigen-like domains 3 [Homo ... 113 3e-25
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens] 111 1e-24
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 721 bits (1860), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE
Sbjct: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
Query: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120
HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP
Sbjct: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120
Query: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180
CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY
Sbjct: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180
Query: 181 CLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
CLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC
Sbjct: 181 CLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
Query: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC
Sbjct: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
Query: 301 KKCYEKFPLELKKRLKKLAETLGRK 325
KKCYEKFPLELKKRLKKLAETLGRK
Sbjct: 301 KKCYEKFPLELKKRLKKLAETLGRK 325
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 639 bits (1648), Expect = 0.0
Identities = 278/325 (85%), Positives = 307/325 (94%)
Query: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
M++ALA+A C+RC+ F+PAE+IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYCE
Sbjct: 28 MSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 87
Query: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120
HDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCRP
Sbjct: 88 HDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 147
Query: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180
CHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CGKELTA+ARELKGELY
Sbjct: 148 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELY 207
Query: 181 CLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
CLPCHDKMGVPICGACRRPIEGRVVNA+GKQWHVEHFVCAKCEKPFLGHRHYE+KGLAYC
Sbjct: 208 CLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 267
Query: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
ETHYNQLFGDVC++C+ VIEGDVVSALNKAWCV+CF+CSTCN+KLTLKNKFVEFDMKPVC
Sbjct: 268 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVC 327
Query: 301 KKCYEKFPLELKKRLKKLAETLGRK 325
K+CYEKFPLELKKRLKKL+E RK
Sbjct: 328 KRCYEKFPLELKKRLKKLSELTSRK 352
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 639 bits (1648), Expect = 0.0
Identities = 278/325 (85%), Positives = 307/325 (94%)
Query: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
M++ALA+A C+RC+ F+PAE+IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYCE
Sbjct: 1 MSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 60
Query: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120
HDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCRP
Sbjct: 61 HDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 120
Query: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180
CHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CGKELTA+ARELKGELY
Sbjct: 121 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELY 180
Query: 181 CLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
CLPCHDKMGVPICGACRRPIEGRVVNA+GKQWHVEHFVCAKCEKPFLGHRHYE+KGLAYC
Sbjct: 181 CLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 240
Query: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
ETHYNQLFGDVC++C+ VIEGDVVSALNKAWCV+CF+CSTCN+KLTLKNKFVEFDMKPVC
Sbjct: 241 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVC 300
Query: 301 KKCYEKFPLELKKRLKKLAETLGRK 325
K+CYEKFPLELKKRLKKL+E RK
Sbjct: 301 KRCYEKFPLELKKRLKKLSELTSRK 325
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 639 bits (1648), Expect = 0.0
Identities = 278/325 (85%), Positives = 307/325 (94%)
Query: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
M++ALA+A C+RC+ F+PAE+IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYCE
Sbjct: 6 MSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 65
Query: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120
HDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCRP
Sbjct: 66 HDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 125
Query: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180
CHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CGKELTA+ARELKGELY
Sbjct: 126 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELY 185
Query: 181 CLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
CLPCHDKMGVPICGACRRPIEGRVVNA+GKQWHVEHFVCAKCEKPFLGHRHYE+KGLAYC
Sbjct: 186 CLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 245
Query: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
ETHYNQLFGDVC++C+ VIEGDVVSALNKAWCV+CF+CSTCN+KLTLKNKFVEFDMKPVC
Sbjct: 246 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVC 305
Query: 301 KKCYEKFPLELKKRLKKLAETLGRK 325
K+CYEKFPLELKKRLKKL+E RK
Sbjct: 306 KRCYEKFPLELKKRLKKLSELTSRK 330
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 639 bits (1648), Expect = 0.0
Identities = 278/325 (85%), Positives = 307/325 (94%)
Query: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
M++ALA+A C+RC+ F+PAE+IVNSNGELYHE CFVCAQCF+ FPEGLFYEFEGRKYCE
Sbjct: 30 MSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 89
Query: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120
HDFQMLFAPCC CGEFIIGRVIKAMNN+WHP CFRC+LC LAD+GFVKNAGRHLCRP
Sbjct: 90 HDFQMLFAPCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRP 149
Query: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELY 180
CHNREKA+GLGKYICQ+CH +IDEQPL+F++D YHPDHFNC +CGKELTA+ARELKGELY
Sbjct: 150 CHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELY 209
Query: 181 CLPCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
CLPCHDKMGVPICGACRRPIEGRVVNA+GKQWHVEHFVCAKCEKPFLGHRHYE+KGLAYC
Sbjct: 210 CLPCHDKMGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYC 269
Query: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
ETHYNQLFGDVC++C+ VIEGDVVSALNKAWCV+CF+CSTCN+KLTLKNKFVEFDMKPVC
Sbjct: 270 ETHYNQLFGDVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVC 329
Query: 301 KKCYEKFPLELKKRLKKLAETLGRK 325
K+CYEKFPLELKKRLKKL+E RK
Sbjct: 330 KRCYEKFPLELKKRLKKLSELTSRK 354
>gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo
sapiens]
Length = 248
Score = 373 bits (957), Expect = e-103
Identities = 165/167 (98%), Positives = 166/167 (99%)
Query: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
MANALASATCERCKGGFAPAE IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE
Sbjct: 63 MANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 122
Query: 61 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 120
HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP
Sbjct: 123 HDFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP 182
Query: 121 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKE 167
CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCG+E
Sbjct: 183 CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQE 229
Score = 73.9 bits (180), Expect = 2e-13
Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
Query: 204 VVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV 263
+VN+ G+ +H + FVCA+C + F YE +G YCE + LF C C I G V
Sbjct: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRV 144
Query: 264 VSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
+ A+N +W CF C C L FV+ + +C+ C+ +
Sbjct: 145 IKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 186
Score = 60.5 bits (145), Expect = 2e-09
Identities = 41/163 (25%), Positives = 65/163 (39%), Gaps = 8/163 (4%)
Query: 127 ARGLGKYICQKCHA-IIDEQPLIFKN-DPYHPDHFNCANCGKELTADA-RELKGELYCLP 183
A L C++C + ++ N + YH F CA C ++ E +G YC
Sbjct: 64 ANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEH 123
Query: 184 CHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETH 243
+ P C C I GRV+ AM WH E F C C++ + G C
Sbjct: 124 DFQMLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 183
Query: 244 YNQ-----LFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTC 281
+N+ L +C C+ +I+ + N + + F C+ C
Sbjct: 184 HNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC 226
Score = 36.2 bits (82), Expect = 0.041
Identities = 25/107 (23%), Positives = 46/107 (42%), Gaps = 7/107 (6%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE--HD 62
L + C +C G +++ + +H +CF C C + + F + GR C H+
Sbjct: 128 LFAPCCHQC--GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHN 185
Query: 63 FQM---LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLAD 106
+ L C +C I + + N+ +HP+ F C C + +D
Sbjct: 186 REKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGQEGSD 232
>gi|239758027 PREDICTED: similar to LIM and senescent cell
antigen-like domains 1 [Homo sapiens]
Length = 116
Score = 208 bits (530), Expect = 5e-54
Identities = 91/91 (100%), Positives = 91/91 (100%)
Query: 75 GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 134
GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI
Sbjct: 26 GEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYI 85
Query: 135 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 165
CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG
Sbjct: 86 CQKCHAIIDEQPLIFKNDPYHPDHFNCANCG 116
Score = 46.6 bits (109), Expect = 3e-05
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 8/79 (10%)
Query: 151 NDPYHPDHFNCANCGKELTADARELK--GELYCLPCHDK-----MGVPICGACRRPIEGR 203
N+ +HP+ F C C +E+ AD +K G C PCH++ +G IC C I+ +
Sbjct: 38 NNSWHPECFRCDLC-QEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQ 96
Query: 204 VVNAMGKQWHVEHFVCAKC 222
+ +H +HF CA C
Sbjct: 97 PLIFKNDPYHPDHFNCANC 115
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 5/87 (5%)
Query: 200 IEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQ-----LFGDVCFH 254
I GRV+ AM WH E F C C++ + G C +N+ L +C
Sbjct: 29 IIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQK 88
Query: 255 CNRVIEGDVVSALNKAWCVNCFACSTC 281
C+ +I+ + N + + F C+ C
Sbjct: 89 CHAIIDEQPLIFKNDPYHPDHFNCANC 115
Score = 35.0 bits (79), Expect = 0.091
Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
Query: 22 KIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE--HDFQM---LFAPCCHQCGE 76
+++ + +H +CF C C + + F + GR C H+ + L C +C
Sbjct: 32 RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHA 91
Query: 77 FIIGRVIKAMNNSWHPECFRCDLC 100
I + + N+ +HP+ F C C
Sbjct: 92 IIDEQPLIFKNDPYHPDHFNCANC 115
Score = 32.3 bits (72), Expect = 0.59
Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Query: 259 IEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
I G V+ A+N +W CF C C L FV+ + +C+ C+ +
Sbjct: 29 IIGRVIKAMNNSWHPECFRCDLCQEVLA-DIGFVKNAGRHLCRPCHNR 75
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 149 bits (375), Expect = 4e-36
Identities = 80/238 (33%), Positives = 117/238 (49%), Gaps = 9/238 (3%)
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARG 129
C C + I G+V+ AM +WHPE F C CQE + F + G+ C + HN R
Sbjct: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 249
Query: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKM 188
C C+ I ++ + + +HP+HF CA CG + E G+ YC + M
Sbjct: 250 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 304
Query: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
P CG C R I ++A+ WH E FVC +C PF+ +E G YCE HY++
Sbjct: 305 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364
Query: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
G +C C + I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 365 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 421
Score = 138 bits (348), Expect = 6e-33
Identities = 79/246 (32%), Positives = 121/246 (49%), Gaps = 10/246 (4%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
+A C CK A ++V + G+ +H + FVC C ++ F+E +G+ YCE D+
Sbjct: 186 VAKGVCGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 243
Query: 65 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 124
LF+P C+ C I+ +V+ A++ +WHPE F C C GF + G+ CR +
Sbjct: 244 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 303
Query: 125 EKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKE-LTADARELKGELYC-L 182
A C C I E + N +HP+ F C C + E G+ YC +
Sbjct: 304 MFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEV 358
Query: 183 PCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCET 242
H++ G +C C++PI GR + AM K++H EHFVCA C K E+ YC+
Sbjct: 359 HYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 417
Query: 243 HYNQLF 248
+ +LF
Sbjct: 418 CFLKLF 423
Score = 114 bits (285), Expect = 1e-25
Identities = 60/178 (33%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKM 188
+ K +C C I Q + +HP+HF C +C +E+ + + E G+ YC + +
Sbjct: 186 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
Query: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
P C C PI +VV A+ + WH EHF CA+C F +E+ G AYC Y +F
Sbjct: 246 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 305
Query: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
C C R I + +SALN W CF C C T + F E D +P C+ Y +
Sbjct: 306 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 362
Score = 105 bits (263), Expect = 4e-23
Identities = 52/124 (41%), Positives = 70/124 (56%), Gaps = 6/124 (4%)
Query: 186 DKMGVP-----ICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
+K+GV +CGAC++PI G+VV AMGK WH EHFVC C++ +ER G YC
Sbjct: 179 NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 238
Query: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
E Y+ LF C++CN I VV+AL++ W F C+ C + F E D K C
Sbjct: 239 EKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG-FHEKDGKAYC 297
Query: 301 KKCY 304
+K Y
Sbjct: 298 RKDY 301
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 149 bits (375), Expect = 4e-36
Identities = 80/238 (33%), Positives = 117/238 (49%), Gaps = 9/238 (3%)
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARG 129
C C + I G+V+ AM +WHPE F C CQE + F + G+ C + HN R
Sbjct: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 382
Query: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKM 188
C C+ I ++ + + +HP+HF CA CG + E G+ YC + M
Sbjct: 383 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 437
Query: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
P CG C R I ++A+ WH E FVC +C PF+ +E G YCE HY++
Sbjct: 438 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497
Query: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
G +C C + I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 498 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 554
Score = 138 bits (348), Expect = 6e-33
Identities = 79/246 (32%), Positives = 121/246 (49%), Gaps = 10/246 (4%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
+A C CK A ++V + G+ +H + FVC C ++ F+E +G+ YCE D+
Sbjct: 319 VAKGVCGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 376
Query: 65 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 124
LF+P C+ C I+ +V+ A++ +WHPE F C C GF + G+ CR +
Sbjct: 377 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 436
Query: 125 EKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKE-LTADARELKGELYC-L 182
A C C I E + N +HP+ F C C + E G+ YC +
Sbjct: 437 MFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEV 491
Query: 183 PCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCET 242
H++ G +C C++PI GR + AM K++H EHFVCA C K E+ YC+
Sbjct: 492 HYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 550
Query: 243 HYNQLF 248
+ +LF
Sbjct: 551 CFLKLF 556
Score = 114 bits (285), Expect = 1e-25
Identities = 60/178 (33%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKM 188
+ K +C C I Q + +HP+HF C +C +E+ + + E G+ YC + +
Sbjct: 319 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
Query: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
P C C PI +VV A+ + WH EHF CA+C F +E+ G AYC Y +F
Sbjct: 379 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 438
Query: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
C C R I + +SALN W CF C C T + F E D +P C+ Y +
Sbjct: 439 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 495
Score = 105 bits (263), Expect = 4e-23
Identities = 52/124 (41%), Positives = 70/124 (56%), Gaps = 6/124 (4%)
Query: 186 DKMGVP-----ICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
+K+GV +CGAC++PI G+VV AMGK WH EHFVC C++ +ER G YC
Sbjct: 312 NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 371
Query: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
E Y+ LF C++CN I VV+AL++ W F C+ C + F E D K C
Sbjct: 372 EKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG-FHEKDGKAYC 430
Query: 301 KKCY 304
+K Y
Sbjct: 431 RKDY 434
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 149 bits (375), Expect = 4e-36
Identities = 80/238 (33%), Positives = 117/238 (49%), Gaps = 9/238 (3%)
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLC-RPCHNREKARG 129
C C + I G+V+ AM +WHPE F C CQE + F + G+ C + HN R
Sbjct: 358 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR- 416
Query: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKM 188
C C+ I ++ + + +HP+HF CA CG + E G+ YC + M
Sbjct: 417 -----CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDM 471
Query: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
P CG C R I ++A+ WH E FVC +C PF+ +E G YCE HY++
Sbjct: 472 FAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 531
Query: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
G +C C + I G ++A+ K + F C+ C +L K F E + KP C+ C+ K
Sbjct: 532 GSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLN-KGTFKEQNDKPYCQNCFLK 588
Score = 138 bits (348), Expect = 6e-33
Identities = 79/246 (32%), Positives = 121/246 (49%), Gaps = 10/246 (4%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
+A C CK A ++V + G+ +H + FVC C ++ F+E +G+ YCE D+
Sbjct: 353 VAKGVCGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYH 410
Query: 65 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 124
LF+P C+ C I+ +V+ A++ +WHPE F C C GF + G+ CR +
Sbjct: 411 NLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFD 470
Query: 125 EKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKE-LTADARELKGELYC-L 182
A C C I E + N +HP+ F C C + E G+ YC +
Sbjct: 471 MFAPK-----CGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEV 525
Query: 183 PCHDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCET 242
H++ G +C C++PI GR + AM K++H EHFVCA C K E+ YC+
Sbjct: 526 HYHERRG-SLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 584
Query: 243 HYNQLF 248
+ +LF
Sbjct: 585 CFLKLF 590
Score = 114 bits (285), Expect = 1e-25
Identities = 60/178 (33%), Positives = 86/178 (48%), Gaps = 2/178 (1%)
Query: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKM 188
+ K +C C I Q + +HP+HF C +C +E+ + + E G+ YC + +
Sbjct: 353 VAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 412
Query: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
P C C PI +VV A+ + WH EHF CA+C F +E+ G AYC Y +F
Sbjct: 413 FSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMF 472
Query: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
C C R I + +SALN W CF C C T + F E D +P C+ Y +
Sbjct: 473 APKCGGCARAILENYISALNTLWHPECFVCRECFTPF-VNGSFFEHDGQPYCEVHYHE 529
Score = 105 bits (263), Expect = 4e-23
Identities = 52/124 (41%), Positives = 70/124 (56%), Gaps = 6/124 (4%)
Query: 186 DKMGVP-----ICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
+K+GV +CGAC++PI G+VV AMGK WH EHFVC C++ +ER G YC
Sbjct: 346 NKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYC 405
Query: 241 ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVC 300
E Y+ LF C++CN I VV+AL++ W F C+ C + F E D K C
Sbjct: 406 EKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEG-FHEKDGKAYC 464
Query: 301 KKCY 304
+K Y
Sbjct: 465 RKDY 468
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 140 bits (353), Expect = 2e-33
Identities = 82/241 (34%), Positives = 118/241 (48%), Gaps = 8/241 (3%)
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 130
C C + I G+VI A+ SWHPE F C C+E + F + +G C +++ L
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 211
Query: 131 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKMG 189
C C A I ++ L N +HP+HF C++CG+ A+ E + YC M
Sbjct: 212 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 271
Query: 190 VPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFG 249
P CG C RP+ ++AM WH E FVC C F +E G +CE HY+ G
Sbjct: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
Query: 250 DVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK-FP 308
+C C + I G +SA+ + F C+ C T+L+ K F E + K C+ C+ K FP
Sbjct: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLS-KGIFREQNDKTYCQPCFNKLFP 390
Query: 309 L 309
L
Sbjct: 391 L 391
Score = 139 bits (350), Expect = 3e-33
Identities = 77/231 (33%), Positives = 116/231 (50%), Gaps = 8/231 (3%)
Query: 20 AEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFII 79
A K++++ G+ +H + FVC C ++ F+E G YC +D+ LF+P C C I+
Sbjct: 165 AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL 224
Query: 80 GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCH 139
+V+ AMN +WHPE F C C EV GF + + C R+ + C C+
Sbjct: 225 DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLAMFSPKCGGCN 279
Query: 140 AIIDEQPLIFKNDPYHPDHFNCANCGKEL-TADARELKGELYC-LPCHDKMGVPICGACR 197
+ E L + +HP+ F C +C T EL G +C L H + G +C C
Sbjct: 280 RPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT-LCHGCG 338
Query: 198 RPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
+PI GR ++AMG ++H EHFVCA C E+ YC+ +N+LF
Sbjct: 339 QPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
Score = 87.0 bits (214), Expect = 2e-17
Identities = 41/114 (35%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Query: 12 RCKGGFAPA-EKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPC 70
+C G P E +++ ++H +CFVC CF F G F+E +GR +CE +
Sbjct: 274 KCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTL 333
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 124
CH CG+ I GR I AM +HPE F C C L+ F + + C+PC N+
Sbjct: 334 CHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 140 bits (353), Expect = 2e-33
Identities = 82/241 (34%), Positives = 118/241 (48%), Gaps = 8/241 (3%)
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 130
C C + I G+VI A+ SWHPE F C C+E + F + +G C +++ L
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 206
Query: 131 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKMG 189
C C A I ++ L N +HP+HF C++CG+ A+ E + YC M
Sbjct: 207 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 266
Query: 190 VPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFG 249
P CG C RP+ ++AM WH E FVC C F +E G +CE HY+ G
Sbjct: 267 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 326
Query: 250 DVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK-FP 308
+C C + I G +SA+ + F C+ C T+L+ K F E + K C+ C+ K FP
Sbjct: 327 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLS-KGIFREQNDKTYCQPCFNKLFP 385
Query: 309 L 309
L
Sbjct: 386 L 386
Score = 139 bits (350), Expect = 3e-33
Identities = 77/231 (33%), Positives = 116/231 (50%), Gaps = 8/231 (3%)
Query: 20 AEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFII 79
A K++++ G+ +H + FVC C ++ F+E G YC +D+ LF+P C C I+
Sbjct: 160 AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL 219
Query: 80 GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCH 139
+V+ AMN +WHPE F C C EV GF + + C R+ + C C+
Sbjct: 220 DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLAMFSPKCGGCN 274
Query: 140 AIIDEQPLIFKNDPYHPDHFNCANCGKEL-TADARELKGELYC-LPCHDKMGVPICGACR 197
+ E L + +HP+ F C +C T EL G +C L H + G +C C
Sbjct: 275 RPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT-LCHGCG 333
Query: 198 RPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
+PI GR ++AMG ++H EHFVCA C E+ YC+ +N+LF
Sbjct: 334 QPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
Score = 87.0 bits (214), Expect = 2e-17
Identities = 41/114 (35%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Query: 12 RCKGGFAPA-EKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPC 70
+C G P E +++ ++H +CFVC CF F G F+E +GR +CE +
Sbjct: 269 KCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTL 328
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 124
CH CG+ I GR I AM +HPE F C C L+ F + + C+PC N+
Sbjct: 329 CHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 382
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 135 bits (341), Expect = 4e-32
Identities = 75/238 (31%), Positives = 111/238 (46%), Gaps = 9/238 (3%)
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH-NREKARG 129
C C + I G+V+ A+ +WHPE F C C L F + G C C+ R R
Sbjct: 228 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 286
Query: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKM 188
C C+ I + + +HP+HF C +CG+ + E +G YC ++
Sbjct: 287 -----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQL 341
Query: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
P C C+ PI ++A+ WH + FVC +C PF G +E +G CE H++
Sbjct: 342 FAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARR 401
Query: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
G +C C + G VSAL + + + F C+ C LT K F E KP C+ C+ K
Sbjct: 402 GSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERAGKPYCQPCFLK 458
Score = 120 bits (300), Expect = 2e-27
Identities = 72/245 (29%), Positives = 107/245 (43%), Gaps = 8/245 (3%)
Query: 6 ASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQM 65
A C C A ++V + G +H + FVC C F+E +G +C +
Sbjct: 224 AKGLCGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 281
Query: 66 LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE 125
F+P C C + I +++ A+ WHPE F C C E D GF + GR C R
Sbjct: 282 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 336
Query: 126 KARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPC 184
L CQ C I + + + +HPD F C C + + E +G C
Sbjct: 337 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 396
Query: 185 HDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHY 244
+C C P+ GR V+A+G+++H +HF C C +P ER G YC+ +
Sbjct: 397 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 456
Query: 245 NQLFG 249
+LFG
Sbjct: 457 LKLFG 461
Score = 114 bits (286), Expect = 9e-26
Identities = 57/171 (33%), Positives = 83/171 (48%), Gaps = 2/171 (1%)
Query: 132 KYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADAR-ELKGELYCLPCHDKMGV 190
K +C C+ I Q + +HP+HF C C L + E G +C C+ +
Sbjct: 225 KGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFS 284
Query: 191 PICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 250
P CG C +PI ++V A+G WH EHF C C +PF +ER+G YC + QLF
Sbjct: 285 PRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 344
Query: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCK 301
C C I + +SAL+ W +CF C C + F E + +P+C+
Sbjct: 345 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFS-GGSFFEHEGRPLCE 394
Score = 89.0 bits (219), Expect = 5e-18
Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
L + C+ C+G + +++ L+H CFVC +CF F G F+E EGR CE+ F
Sbjct: 341 LFAPRCQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFH 398
Query: 65 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 121
C CG + GR + A+ +HP+ F C C L F + AG+ C+PC
Sbjct: 399 ARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 135 bits (341), Expect = 4e-32
Identities = 75/238 (31%), Positives = 111/238 (46%), Gaps = 9/238 (3%)
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH-NREKARG 129
C C + I G+V+ A+ +WHPE F C C L F + G C C+ R R
Sbjct: 211 CGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR- 269
Query: 130 LGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKM 188
C C+ I + + +HP+HF C +CG+ + E +G YC ++
Sbjct: 270 -----CGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQL 324
Query: 189 GVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248
P C C+ PI ++A+ WH + FVC +C PF G +E +G CE H++
Sbjct: 325 FAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARR 384
Query: 249 GDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
G +C C + G VSAL + + + F C+ C LT K F E KP C+ C+ K
Sbjct: 385 GSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERAGKPYCQPCFLK 441
Score = 120 bits (300), Expect = 2e-27
Identities = 72/245 (29%), Positives = 107/245 (43%), Gaps = 8/245 (3%)
Query: 6 ASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQM 65
A C C A ++V + G +H + FVC C F+E +G +C +
Sbjct: 207 AKGLCGSCNKPIAG--QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFE 264
Query: 66 LFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE 125
F+P C C + I +++ A+ WHPE F C C E D GF + GR C R
Sbjct: 265 RFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC-----RR 319
Query: 126 KARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPC 184
L CQ C I + + + +HPD F C C + + E +G C
Sbjct: 320 DFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENH 379
Query: 185 HDKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHY 244
+C C P+ GR V+A+G+++H +HF C C +P ER G YC+ +
Sbjct: 380 FHARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439
Query: 245 NQLFG 249
+LFG
Sbjct: 440 LKLFG 444
Score = 114 bits (286), Expect = 9e-26
Identities = 57/171 (33%), Positives = 83/171 (48%), Gaps = 2/171 (1%)
Query: 132 KYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADAR-ELKGELYCLPCHDKMGV 190
K +C C+ I Q + +HP+HF C C L + E G +C C+ +
Sbjct: 208 KGLCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFS 267
Query: 191 PICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 250
P CG C +PI ++V A+G WH EHF C C +PF +ER+G YC + QLF
Sbjct: 268 PRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAP 327
Query: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCK 301
C C I + +SAL+ W +CF C C + F E + +P+C+
Sbjct: 328 RCQGCQGPILDNYISALSALWHPDCFVCRECFAPFS-GGSFFEHEGRPLCE 377
Score = 89.0 bits (219), Expect = 5e-18
Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
L + C+ C+G + +++ L+H CFVC +CF F G F+E EGR CE+ F
Sbjct: 324 LFAPRCQGCQGPIL--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFH 381
Query: 65 MLFAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPC 121
C CG + GR + A+ +HP+ F C C L F + AG+ C+PC
Sbjct: 382 ARRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 127 bits (320), Expect = 1e-29
Identities = 60/171 (35%), Positives = 91/171 (53%), Gaps = 4/171 (2%)
Query: 134 ICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADAR-ELKGELYCLPCHDKMGVPI 192
+C +CH +I + L+ YHP+ F C+ CGK L E KG ++C PC+D P
Sbjct: 247 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 306
Query: 193 CGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVC 252
C C++ I G +++A+ WHV F CA C+ P Y +G+ YCE Y ++FG C
Sbjct: 307 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 366
Query: 253 FHCN-RVIEGD-VVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCK 301
C+ ++ GD + AL +W CF C+ C L K + + D +P+CK
Sbjct: 367 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKD-RPLCK 416
Score = 94.0 bits (232), Expect = 2e-19
Identities = 57/178 (32%), Positives = 83/178 (46%), Gaps = 8/178 (4%)
Query: 69 PCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKAR 128
P CHQC + I GR + A+ +++HPE F C C +VL + GF + G C PC++ A
Sbjct: 246 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 129 GLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADAREL-KGELYCLPCHDK 187
C KC I + + +H F CA C + A + +G YC ++K
Sbjct: 306 S-----CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEK 360
Query: 188 MGVPICGACRRPIEG--RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETH 243
M C C I+ R + A+G WH FVCA C+ G Y +K C++H
Sbjct: 361 MFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 418
Score = 88.2 bits (217), Expect = 9e-18
Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 191 PICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 250
P+C C + I GR + A+G +H E FVC++C K +E KG +C Y+ +
Sbjct: 246 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
C C + I G+++ AL W V+CF C+ C T + + ++E + P C++ YEK
Sbjct: 306 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYME-EGVPYCERDYEK 360
Score = 32.0 bits (71), Expect = 0.77
Identities = 14/51 (27%), Positives = 22/51 (43%)
Query: 10 CERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
C C ++ + + G +H+ CFVCA C FY + R C+
Sbjct: 366 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 416
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 127 bits (320), Expect = 1e-29
Identities = 60/171 (35%), Positives = 91/171 (53%), Gaps = 4/171 (2%)
Query: 134 ICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADAR-ELKGELYCLPCHDKMGVPI 192
+C +CH +I + L+ YHP+ F C+ CGK L E KG ++C PC+D P
Sbjct: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
Query: 193 CGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVC 252
C C++ I G +++A+ WHV F CA C+ P Y +G+ YCE Y ++FG C
Sbjct: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
Query: 253 FHCN-RVIEGD-VVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCK 301
C+ ++ GD + AL +W CF C+ C L K + + D +P+CK
Sbjct: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKD-RPLCK 450
Score = 94.0 bits (232), Expect = 2e-19
Identities = 57/178 (32%), Positives = 83/178 (46%), Gaps = 8/178 (4%)
Query: 69 PCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKAR 128
P CHQC + I GR + A+ +++HPE F C C +VL + GF + G C PC++ A
Sbjct: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 129 GLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADAREL-KGELYCLPCHDK 187
C KC I + + +H F CA C + A + +G YC ++K
Sbjct: 340 S-----CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEK 394
Query: 188 MGVPICGACRRPIEG--RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETH 243
M C C I+ R + A+G WH FVCA C+ G Y +K C++H
Sbjct: 395 MFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
Score = 88.2 bits (217), Expect = 9e-18
Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 191 PICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 250
P+C C + I GR + A+G +H E FVC++C K +E KG +C Y+ +
Sbjct: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
C C + I G+++ AL W V+CF C+ C T + + ++E + P C++ YEK
Sbjct: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYME-EGVPYCERDYEK 394
Score = 32.0 bits (71), Expect = 0.77
Identities = 14/51 (27%), Positives = 22/51 (43%)
Query: 10 CERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
C C ++ + + G +H+ CFVCA C FY + R C+
Sbjct: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 127 bits (319), Expect = 1e-29
Identities = 68/172 (39%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Query: 134 ICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELT-ADARELKGELYCLPCHDKMGVPI 192
+C C+ +I L+ +HP+ FNCA+C + E KG LYC C++K P
Sbjct: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 369
Query: 193 CGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVC 252
CG C+R I G V++A+ + WHV FVC C KP + + G YCET Y LFG +C
Sbjct: 370 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 429
Query: 253 FHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKK 302
C IE GD+ + AL W CF CS C L + F + D KP+CKK
Sbjct: 430 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKD-KPLCKK 480
Score = 94.0 bits (232), Expect = 2e-19
Identities = 55/178 (30%), Positives = 79/178 (44%), Gaps = 8/178 (4%)
Query: 69 PCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKAR 128
P C C + I G + A+ SWHPE F C C+ +A IGFV+ G C C+ + A
Sbjct: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
Query: 129 GLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDK 187
C +C I + + +H F C CGK + + L+ GE YC +
Sbjct: 369 E-----CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYA 423
Query: 188 MGVPICGACRRPIEG--RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETH 243
+ IC C PIE + A+G WH FVC+ C + G + +K C+ H
Sbjct: 424 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 481
Score = 90.9 bits (224), Expect = 1e-18
Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 191 PICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 250
P+C C + I G + A+GK WH E F CA C+ E KG YCE Y + F
Sbjct: 309 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
Query: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304
C C R I G+V+SAL + W V+CF C C K N F D +P C+ Y
Sbjct: 369 ECGRCQRKILGEVISALKQTWHVSCFVCVACG-KPIRNNVFHLEDGEPYCETDY 421
Score = 69.3 bits (168), Expect = 4e-12
Identities = 35/113 (30%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Query: 10 CERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAP 69
C RC+ +++++ + +H CFVC C + +F+ +G YCE D+ LF
Sbjct: 370 CGRCQRKILG--EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427
Query: 70 CCHQCGEFII---GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 119
CH C EF I ++A+ +WH CF C +C E L F + LC+
Sbjct: 428 ICHGC-EFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
Score = 65.5 bits (158), Expect = 6e-11
Identities = 42/143 (29%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Query: 28 GELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMN 87
G+ +H + F CA C F E +G YCE ++ FAP C +C I+G VI A+
Sbjct: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
Query: 88 NSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPL 147
+WH CF C C + + + F G C + L IC C I+ +
Sbjct: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY-----YALFGTICHGCEFPIEAGDM 441
Query: 148 IFKNDPY--HPDHFNCANCGKEL 168
+ Y H F C+ C + L
Sbjct: 442 FLEALGYTWHDTCFVCSVCCESL 464
Score = 46.2 bits (108), Expect = 4e-05
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307
+C HCN+VI G + AL K+W F C+ C + FVE C+ CYEKF
Sbjct: 310 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIG-FVEEKGALYCELCYEKF 365
Score = 33.5 bits (75), Expect = 0.26
Identities = 13/57 (22%), Positives = 25/57 (43%)
Query: 4 ALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
AL C C+ + + + G +H+ CFVC+ C + F+ + + C+
Sbjct: 423 ALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 127 bits (319), Expect = 1e-29
Identities = 68/172 (39%), Positives = 91/172 (52%), Gaps = 4/172 (2%)
Query: 134 ICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELT-ADARELKGELYCLPCHDKMGVPI 192
+C C+ +I L+ +HP+ FNCA+C + E KG LYC C++K P
Sbjct: 419 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPE 478
Query: 193 CGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVC 252
CG C+R I G V++A+ + WHV FVC C KP + + G YCET Y LFG +C
Sbjct: 479 CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTIC 538
Query: 253 FHCNRVIE-GDV-VSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKK 302
C IE GD+ + AL W CF CS C L + F + D KP+CKK
Sbjct: 539 HGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKD-KPLCKK 589
Score = 94.0 bits (232), Expect = 2e-19
Identities = 55/178 (30%), Positives = 79/178 (44%), Gaps = 8/178 (4%)
Query: 69 PCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKAR 128
P C C + I G + A+ SWHPE F C C+ +A IGFV+ G C C+ + A
Sbjct: 418 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477
Query: 129 GLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDK 187
C +C I + + +H F C CGK + + L+ GE YC +
Sbjct: 478 E-----CGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYA 532
Query: 188 MGVPICGACRRPIEG--RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETH 243
+ IC C PIE + A+G WH FVC+ C + G + +K C+ H
Sbjct: 533 LFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 590
Score = 90.9 bits (224), Expect = 1e-18
Identities = 45/114 (39%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 191 PICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 250
P+C C + I G + A+GK WH E F CA C+ E KG YCE Y + F
Sbjct: 418 PMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477
Query: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304
C C R I G+V+SAL + W V+CF C C K N F D +P C+ Y
Sbjct: 478 ECGRCQRKILGEVISALKQTWHVSCFVCVACG-KPIRNNVFHLEDGEPYCETDY 530
Score = 69.3 bits (168), Expect = 4e-12
Identities = 35/113 (30%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Query: 10 CERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAP 69
C RC+ +++++ + +H CFVC C + +F+ +G YCE D+ LF
Sbjct: 479 CGRCQRKILG--EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 536
Query: 70 CCHQCGEFII---GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCR 119
CH C EF I ++A+ +WH CF C +C E L F + LC+
Sbjct: 537 ICHGC-EFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588
Score = 65.5 bits (158), Expect = 6e-11
Identities = 42/143 (29%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Query: 28 GELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMN 87
G+ +H + F CA C F E +G YCE ++ FAP C +C I+G VI A+
Sbjct: 436 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 495
Query: 88 NSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPL 147
+WH CF C C + + + F G C + L IC C I+ +
Sbjct: 496 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY-----YALFGTICHGCEFPIEAGDM 550
Query: 148 IFKNDPY--HPDHFNCANCGKEL 168
+ Y H F C+ C + L
Sbjct: 551 FLEALGYTWHDTCFVCSVCCESL 573
Score = 46.2 bits (108), Expect = 4e-05
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307
+C HCN+VI G + AL K+W F C+ C + FVE C+ CYEKF
Sbjct: 419 MCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIG-FVEEKGALYCELCYEKF 474
Score = 33.5 bits (75), Expect = 0.26
Identities = 13/57 (22%), Positives = 25/57 (43%)
Query: 4 ALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
AL C C+ + + + G +H+ CFVC+ C + F+ + + C+
Sbjct: 532 ALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 120 bits (300), Expect = 2e-27
Identities = 79/282 (28%), Positives = 112/282 (39%), Gaps = 18/282 (6%)
Query: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
F C C + + +G C F A C +C + I + + N WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 150
CFRC C LA+ FV + LC C RE K +G K I + +Q + +K
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
Query: 151 NDPYHPDHFNCANCGKELTADARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNAMG 209
+H D F C+NC + + + KGE YC+ CH+ C C + I +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 210 KQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG-----DVV 264
+ WH + FVC C K G R + YC Y C C I G VV
Sbjct: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 238
Query: 265 SALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 239 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 279
Score = 110 bits (275), Expect = 2e-24
Identities = 61/240 (25%), Positives = 95/240 (39%), Gaps = 13/240 (5%)
Query: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68
TC C+ K V+ +H+ CF CA+C F + + C +
Sbjct: 39 TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
Query: 69 PCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
P C C + I+ + ++ WH +CF C C++V+ F C CH +
Sbjct: 99 PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
Query: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCH 185
A+ C KC+ I + +++ P+H D F C C K+L ++ + YC+ C+
Sbjct: 159 AKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
Query: 186 DKMGVPICGACRRPIEG-----RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
C C+ PI G VV G+ WH F C KC R + YC
Sbjct: 214 KNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 92.8 bits (229), Expect = 4e-19
Identities = 62/221 (28%), Positives = 95/221 (42%), Gaps = 13/221 (5%)
Query: 93 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 150
E F C C++ L +V+ G H C C ++ A C +C I D + + +K
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57
Query: 151 NDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNA 207
N +H F CA C L + K ++ C C + P C C + I + V
Sbjct: 58 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
Query: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGL-AYCETHYNQLFGDVCFHCNRVIEGDVVSA 266
G WH + F C+ C K +G + KG YC T + F C CN+ I ++
Sbjct: 118 KGTVWHKDCFTCSNC-KQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY 176
Query: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307
++ W +CF C TC+ KL +F + + C CY+ F
Sbjct: 177 QDQPWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNF 216
Score = 71.2 bits (173), Expect = 1e-12
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 13/189 (6%)
Query: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
S C+ C ++ V G ++H+ CF C+ C Q G F+ YC +
Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
Query: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
FA C +C + I I + WH +CF C C + LA F ++ C C+
Sbjct: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 217
Query: 127 ARGLGKYICQKCHAII-----DEQPLIFKNDPYHPDHFNCANCGKELTADAREL--KGEL 179
A+ C C I + ++ +H F+C C L A+ R + + ++
Sbjct: 218 AKK-----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNL-ANKRFVFHQEQV 271
Query: 180 YCLPCHDKM 188
YC C K+
Sbjct: 272 YCPDCAKKL 280
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 120 bits (300), Expect = 2e-27
Identities = 79/282 (28%), Positives = 112/282 (39%), Gaps = 18/282 (6%)
Query: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
F C C + + +G C F A C +C + I + + N WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 150
CFRC C LA+ FV + LC C RE K +G K I + +Q + +K
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
Query: 151 NDPYHPDHFNCANCGKELTADARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNAMG 209
+H D F C+NC + + + KGE YC+ CH+ C C + I +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 210 KQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG-----DVV 264
+ WH + FVC C K G R + YC Y C C I G VV
Sbjct: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 238
Query: 265 SALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 239 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 279
Score = 110 bits (275), Expect = 2e-24
Identities = 61/240 (25%), Positives = 95/240 (39%), Gaps = 13/240 (5%)
Query: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68
TC C+ K V+ +H+ CF CA+C F + + C +
Sbjct: 39 TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
Query: 69 PCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
P C C + I+ + ++ WH +CF C C++V+ F C CH +
Sbjct: 99 PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
Query: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCH 185
A+ C KC+ I + +++ P+H D F C C K+L ++ + YC+ C+
Sbjct: 159 AKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
Query: 186 DKMGVPICGACRRPIEG-----RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
C C+ PI G VV G+ WH F C KC R + YC
Sbjct: 214 KNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 92.8 bits (229), Expect = 4e-19
Identities = 62/221 (28%), Positives = 95/221 (42%), Gaps = 13/221 (5%)
Query: 93 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 150
E F C C++ L +V+ G H C C ++ A C +C I D + + +K
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57
Query: 151 NDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNA 207
N +H F CA C L + K ++ C C + P C C + I + V
Sbjct: 58 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
Query: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGL-AYCETHYNQLFGDVCFHCNRVIEGDVVSA 266
G WH + F C+ C K +G + KG YC T + F C CN+ I ++
Sbjct: 118 KGTVWHKDCFTCSNC-KQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY 176
Query: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307
++ W +CF C TC+ KL +F + + C CY+ F
Sbjct: 177 QDQPWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNF 216
Score = 71.2 bits (173), Expect = 1e-12
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 13/189 (6%)
Query: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
S C+ C ++ V G ++H+ CF C+ C Q G F+ YC +
Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
Query: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
FA C +C + I I + WH +CF C C + LA F ++ C C+
Sbjct: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 217
Query: 127 ARGLGKYICQKCHAII-----DEQPLIFKNDPYHPDHFNCANCGKELTADAREL--KGEL 179
A+ C C I + ++ +H F+C C L A+ R + + ++
Sbjct: 218 AKK-----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNL-ANKRFVFHQEQV 271
Query: 180 YCLPCHDKM 188
YC C K+
Sbjct: 272 YCPDCAKKL 280
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 120 bits (300), Expect = 2e-27
Identities = 79/282 (28%), Positives = 112/282 (39%), Gaps = 18/282 (6%)
Query: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
F C C + + +G C F A C +C + I + + N WH
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93
Query: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 150
CFRC C LA+ FV + LC C RE K +G K I + +Q + +K
Sbjct: 94 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 147
Query: 151 NDPYHPDHFNCANCGKELTADARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNAMG 209
+H D F C+NC + + + KGE YC+ CH+ C C + I +
Sbjct: 148 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 207
Query: 210 KQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG-----DVV 264
+ WH + FVC C K G R + YC Y C C I G VV
Sbjct: 208 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 267
Query: 265 SALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 268 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 308
Score = 110 bits (275), Expect = 2e-24
Identities = 61/240 (25%), Positives = 95/240 (39%), Gaps = 13/240 (5%)
Query: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68
TC C+ K V+ +H+ CF CA+C F + + C +
Sbjct: 68 TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 127
Query: 69 PCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
P C C + I+ + ++ WH +CF C C++V+ F C CH +
Sbjct: 128 PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 187
Query: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCH 185
A+ C KC+ I + +++ P+H D F C C K+L ++ + YC+ C+
Sbjct: 188 AKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 242
Query: 186 DKMGVPICGACRRPIEG-----RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
C C+ PI G VV G+ WH F C KC R + YC
Sbjct: 243 KNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 302
Score = 92.8 bits (229), Expect = 4e-19
Identities = 62/221 (28%), Positives = 95/221 (42%), Gaps = 13/221 (5%)
Query: 93 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 150
E F C C++ L +V+ G H C C ++ A C +C I D + + +K
Sbjct: 32 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 86
Query: 151 NDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNA 207
N +H F CA C L + K ++ C C + P C C + I + V
Sbjct: 87 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 146
Query: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGL-AYCETHYNQLFGDVCFHCNRVIEGDVVSA 266
G WH + F C+ C K +G + KG YC T + F C CN+ I ++
Sbjct: 147 KGTVWHKDCFTCSNC-KQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY 205
Query: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307
++ W +CF C TC+ KL +F + + C CY+ F
Sbjct: 206 QDQPWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNF 245
Score = 71.2 bits (173), Expect = 1e-12
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 13/189 (6%)
Query: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
S C+ C ++ V G ++H+ CF C+ C Q G F+ YC +
Sbjct: 127 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 186
Query: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
FA C +C + I I + WH +CF C C + LA F ++ C C+
Sbjct: 187 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 246
Query: 127 ARGLGKYICQKCHAII-----DEQPLIFKNDPYHPDHFNCANCGKELTADAREL--KGEL 179
A+ C C I + ++ +H F+C C L A+ R + + ++
Sbjct: 247 AKK-----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNL-ANKRFVFHQEQV 300
Query: 180 YCLPCHDKM 188
YC C K+
Sbjct: 301 YCPDCAKKL 309
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 120 bits (300), Expect = 2e-27
Identities = 79/282 (28%), Positives = 112/282 (39%), Gaps = 18/282 (6%)
Query: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
F C C + + +G C F A C +C + I + + N WH
Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
Query: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 150
CFRC C LA+ FV + LC C RE K +G K I + +Q + +K
Sbjct: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 134
Query: 151 NDPYHPDHFNCANCGKELTADARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNAMG 209
+H D F C+NC + + + KGE YC+ CH+ C C + I +
Sbjct: 135 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 194
Query: 210 KQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG-----DVV 264
+ WH + FVC C K G R + YC Y C C I G VV
Sbjct: 195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 254
Query: 265 SALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 255 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 295
Score = 110 bits (275), Expect = 2e-24
Identities = 61/240 (25%), Positives = 95/240 (39%), Gaps = 13/240 (5%)
Query: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68
TC C+ K V+ +H+ CF CA+C F + + C +
Sbjct: 55 TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 114
Query: 69 PCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
P C C + I+ + ++ WH +CF C C++V+ F C CH +
Sbjct: 115 PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 174
Query: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCH 185
A+ C KC+ I + +++ P+H D F C C K+L ++ + YC+ C+
Sbjct: 175 AKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229
Query: 186 DKMGVPICGACRRPIEG-----RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
C C+ PI G VV G+ WH F C KC R + YC
Sbjct: 230 KNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289
Score = 92.8 bits (229), Expect = 4e-19
Identities = 62/221 (28%), Positives = 95/221 (42%), Gaps = 13/221 (5%)
Query: 93 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 150
E F C C++ L +V+ G H C C ++ A C +C I D + + +K
Sbjct: 19 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 73
Query: 151 NDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNA 207
N +H F CA C L + K ++ C C + P C C + I + V
Sbjct: 74 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 133
Query: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGL-AYCETHYNQLFGDVCFHCNRVIEGDVVSA 266
G WH + F C+ C K +G + KG YC T + F C CN+ I ++
Sbjct: 134 KGTVWHKDCFTCSNC-KQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY 192
Query: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307
++ W +CF C TC+ KL +F + + C CY+ F
Sbjct: 193 QDQPWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNF 232
Score = 71.2 bits (173), Expect = 1e-12
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 13/189 (6%)
Query: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
S C+ C ++ V G ++H+ CF C+ C Q G F+ YC +
Sbjct: 114 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 173
Query: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
FA C +C + I I + WH +CF C C + LA F ++ C C+
Sbjct: 174 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 233
Query: 127 ARGLGKYICQKCHAII-----DEQPLIFKNDPYHPDHFNCANCGKELTADAREL--KGEL 179
A+ C C I + ++ +H F+C C L A+ R + + ++
Sbjct: 234 AKK-----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNL-ANKRFVFHQEQV 287
Query: 180 YCLPCHDKM 188
YC C K+
Sbjct: 288 YCPDCAKKL 296
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 120 bits (300), Expect = 2e-27
Identities = 79/282 (28%), Positives = 112/282 (39%), Gaps = 18/282 (6%)
Query: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
F C C + + +G C F A C +C + I + + N WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNRE---KARGLGKYICQKCHAIIDEQPLIFK 150
CFRC C LA+ FV + LC C RE K +G K I + +Q + +K
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI------VAGDQNVEYK 118
Query: 151 NDPYHPDHFNCANCGKELTADARELKGE-LYCLPCHDKMGVPICGACRRPIEGRVVNAMG 209
+H D F C+NC + + + KGE YC+ CH+ C C + I +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 210 KQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG-----DVV 264
+ WH + FVC C K G R + YC Y C C I G VV
Sbjct: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 238
Query: 265 SALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
+ ++W CF C C+ L K +FV + C C +K
Sbjct: 239 AYEGQSWHDYCFHCKKCSVNLANK-RFVFHQEQVYCPDCAKK 279
Score = 110 bits (275), Expect = 2e-24
Identities = 61/240 (25%), Positives = 95/240 (39%), Gaps = 13/240 (5%)
Query: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68
TC C+ K V+ +H+ CF CA+C F + + C +
Sbjct: 39 TCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
Query: 69 PCCHQCGEFIIG--RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
P C C + I+ + ++ WH +CF C C++V+ F C CH +
Sbjct: 99 PKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158
Query: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCH 185
A+ C KC+ I + +++ P+H D F C C K+L ++ + YC+ C+
Sbjct: 159 AKH-----CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213
Query: 186 DKMGVPICGACRRPIEG-----RVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC 240
C C+ PI G VV G+ WH F C KC R + YC
Sbjct: 214 KNFVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 92.8 bits (229), Expect = 4e-19
Identities = 62/221 (28%), Positives = 95/221 (42%), Gaps = 13/221 (5%)
Query: 93 ECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFK 150
E F C C++ L +V+ G H C C ++ A C +C I D + + +K
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCAN-----TCVECRKPIGADSKEVHYK 57
Query: 151 NDPYHPDHFNCANCGKELTADARELK-GELYCLPCHDKMGVPICGACRRPIEG--RVVNA 207
N +H F CA C L + K ++ C C + P C C + I + V
Sbjct: 58 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEY 117
Query: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGL-AYCETHYNQLFGDVCFHCNRVIEGDVVSA 266
G WH + F C+ C K +G + KG YC T + F C CN+ I ++
Sbjct: 118 KGTVWHKDCFTCSNC-KQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITY 176
Query: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKF 307
++ W +CF C TC+ KL +F + + C CY+ F
Sbjct: 177 QDQPWHADCFVCVTCSKKLA-GQRFTAVEDQYYCVDCYKNF 216
Score = 71.2 bits (173), Expect = 1e-12
Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 13/189 (6%)
Query: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
S C+ C ++ V G ++H+ CF C+ C Q G F+ YC +
Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
Query: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
FA C +C + I I + WH +CF C C + LA F ++ C C+
Sbjct: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 217
Query: 127 ARGLGKYICQKCHAII-----DEQPLIFKNDPYHPDHFNCANCGKELTADAREL--KGEL 179
A+ C C I + ++ +H F+C C L A+ R + + ++
Sbjct: 218 AKK-----CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNL-ANKRFVFHQEQV 271
Query: 180 YCLPCHDKM 188
YC C K+
Sbjct: 272 YCPDCAKKL 280
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 120 bits (300), Expect = 2e-27
Identities = 77/278 (27%), Positives = 113/278 (40%), Gaps = 16/278 (5%)
Query: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
F C C + + E YC F+ LFA C +CG+ I + + + WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFKN 151
CF C C+ L D F + LC C++ E + CQ+C I + + +K
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
Query: 152 DPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGK 210
+H F C C + + T + +C+PC++K C C++PI V +
Sbjct: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
Query: 211 QWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG----DVVSA 266
WH E FVC C K G R R AYC + L+ C C I G +S
Sbjct: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
Query: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFD--MKPVCKK 302
+ W +CF C C+ L + E D + P C K
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
Score = 108 bits (269), Expect = 8e-24
Identities = 60/231 (25%), Positives = 101/231 (43%), Gaps = 12/231 (5%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
L + TCE C K ++ +HE CF C+QC + F E + C +
Sbjct: 35 LFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94
Query: 65 MLFAPCCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH 122
++ C +C + I+ R ++ +SWH CF C CQ+ + F+ ++ C PC+
Sbjct: 95 NEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154
Query: 123 NREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGEL-YC 181
++ A C +C I + ++ P+H + F C C K+L+ + + YC
Sbjct: 155 EKQHAMQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
Query: 182 LPCHDKMGVPICGACRRPIEG----RVVNAMGKQWHVEHFVCAKCEKPFLG 228
L C + C C PI G + ++ +QWH + F C KC +G
Sbjct: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
Score = 48.5 bits (114), Expect = 8e-06
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 215 EHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV--VSALNKAWC 272
E F C C + G ++ R+ YC + LF + C C + I D +S ++ W
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 273 VNCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304
CF CS C L K F + + +C CY
Sbjct: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCY 93
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 120 bits (300), Expect = 2e-27
Identities = 77/278 (27%), Positives = 113/278 (40%), Gaps = 16/278 (5%)
Query: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
F C C + + E YC F+ LFA C +CG+ I + + + WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFKN 151
CF C C+ L D F + LC C++ E + CQ+C I + + +K
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
Query: 152 DPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGK 210
+H F C C + + T + +C+PC++K C C++PI V +
Sbjct: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
Query: 211 QWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG----DVVSA 266
WH E FVC C K G R R AYC + L+ C C I G +S
Sbjct: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
Query: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFD--MKPVCKK 302
+ W +CF C C+ L + E D + P C K
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
Score = 108 bits (269), Expect = 8e-24
Identities = 60/231 (25%), Positives = 101/231 (43%), Gaps = 12/231 (5%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
L + TCE C K ++ +HE CF C+QC + F E + C +
Sbjct: 35 LFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94
Query: 65 MLFAPCCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH 122
++ C +C + I+ R ++ +SWH CF C CQ+ + F+ ++ C PC+
Sbjct: 95 NEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154
Query: 123 NREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGEL-YC 181
++ A C +C I + ++ P+H + F C C K+L+ + + YC
Sbjct: 155 EKQHAMQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
Query: 182 LPCHDKMGVPICGACRRPIEG----RVVNAMGKQWHVEHFVCAKCEKPFLG 228
L C + C C PI G + ++ +QWH + F C KC +G
Sbjct: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
Score = 48.5 bits (114), Expect = 8e-06
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 215 EHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV--VSALNKAWC 272
E F C C + G ++ R+ YC + LF + C C + I D +S ++ W
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 273 VNCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304
CF CS C L K F + + +C CY
Sbjct: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCY 93
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 120 bits (300), Expect = 2e-27
Identities = 77/278 (27%), Positives = 113/278 (40%), Gaps = 16/278 (5%)
Query: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
F C C + + E YC F+ LFA C +CG+ I + + + WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFKN 151
CF C C+ L D F + LC C++ E + CQ+C I + + +K
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
Query: 152 DPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGK 210
+H F C C + + T + +C+PC++K C C++PI V +
Sbjct: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
Query: 211 QWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG----DVVSA 266
WH E FVC C K G R R AYC + L+ C C I G +S
Sbjct: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
Query: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFD--MKPVCKK 302
+ W +CF C C+ L + E D + P C K
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
Score = 108 bits (269), Expect = 8e-24
Identities = 60/231 (25%), Positives = 101/231 (43%), Gaps = 12/231 (5%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
L + TCE C K ++ +HE CF C+QC + F E + C +
Sbjct: 35 LFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94
Query: 65 MLFAPCCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH 122
++ C +C + I+ R ++ +SWH CF C CQ+ + F+ ++ C PC+
Sbjct: 95 NEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154
Query: 123 NREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGEL-YC 181
++ A C +C I + ++ P+H + F C C K+L+ + + YC
Sbjct: 155 EKQHAMQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
Query: 182 LPCHDKMGVPICGACRRPIEG----RVVNAMGKQWHVEHFVCAKCEKPFLG 228
L C + C C PI G + ++ +QWH + F C KC +G
Sbjct: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
Score = 48.5 bits (114), Expect = 8e-06
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 215 EHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV--VSALNKAWC 272
E F C C + G ++ R+ YC + LF + C C + I D +S ++ W
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 273 VNCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304
CF CS C L K F + + +C CY
Sbjct: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCY 93
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 120 bits (300), Expect = 2e-27
Identities = 77/278 (27%), Positives = 113/278 (40%), Gaps = 16/278 (5%)
Query: 36 FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93
F C C + + E YC F+ LFA C +CG+ I + + + WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 94 CFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFKN 151
CF C C+ L D F + LC C++ E + CQ+C I + + +K
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
Query: 152 DPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGK 210
+H F C C + + T + +C+PC++K C C++PI V +
Sbjct: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
Query: 211 QWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG----DVVSA 266
WH E FVC C K G R R AYC + L+ C C I G +S
Sbjct: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
Query: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFD--MKPVCKK 302
+ W +CF C C+ L + E D + P C K
Sbjct: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
Score = 108 bits (269), Expect = 8e-24
Identities = 60/231 (25%), Positives = 101/231 (43%), Gaps = 12/231 (5%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
L + TCE C K ++ +HE CF C+QC + F E + C +
Sbjct: 35 LFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94
Query: 65 MLFAPCCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH 122
++ C +C + I+ R ++ +SWH CF C CQ+ + F+ ++ C PC+
Sbjct: 95 NEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154
Query: 123 NREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGEL-YC 181
++ A C +C I + ++ P+H + F C C K+L+ + + YC
Sbjct: 155 EKQHAMQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
Query: 182 LPCHDKMGVPICGACRRPIEG----RVVNAMGKQWHVEHFVCAKCEKPFLG 228
L C + C C PI G + ++ +QWH + F C KC +G
Sbjct: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
Score = 48.5 bits (114), Expect = 8e-06
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 215 EHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV--VSALNKAWC 272
E F C C + G ++ R+ YC + LF + C C + I D +S ++ W
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 273 VNCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304
CF CS C L K F + + +C CY
Sbjct: 63 EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCY 93
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 117 bits (293), Expect = 1e-26
Identities = 77/284 (27%), Positives = 119/284 (41%), Gaps = 15/284 (5%)
Query: 34 QCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWH 91
+ F CA+C + + + + YC + FA C +C + I R + + +H
Sbjct: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
Query: 92 PECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIF 149
CFRC CQ LAD F LC C+ + C C + + L +
Sbjct: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQ-----CSACGETVMPGSRKLEY 117
Query: 150 KNDPYHPDHFNCANCGKELTADAREL-KGELYCLPCHDKMGVPICGACRRPIEGRVVNAM 208
+H F C+ C + L + + KG YC+PC++ P C C + + V
Sbjct: 118 GGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYR 177
Query: 209 GKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVI----EGDVV 264
+ WH E VC C+ P G + R YC + +LF C C R I G V
Sbjct: 178 DQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYV 237
Query: 265 SALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFP 308
S ++ W NCF+C+ C+T L + FV + +C+ C + P
Sbjct: 238 SFEDRHWHHNCFSCARCSTSL-VGQGFVPDGDQVLCQGCSQAGP 280
Score = 110 bits (274), Expect = 2e-24
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 12/227 (5%)
Query: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68
TC C+ + + +HE CF C +C + + F + C + F+
Sbjct: 39 TCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFS 98
Query: 69 PCCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
C CGE ++ R ++ +WH CF C C++ L FV + G H C PC+ +
Sbjct: 99 SQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKF 158
Query: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGE-LYCLPCH 185
A C +C + + + +++ P+H + C C L + E YC+ C
Sbjct: 159 APR-----CARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACF 213
Query: 186 DKMGVPICGACRRPI----EGRVVNAMGKQWHVEHFVCAKCEKPFLG 228
++ P C +C+RPI G+ V+ + WH F CA+C +G
Sbjct: 214 GELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVG 260
Score = 76.3 bits (186), Expect = 4e-14
Identities = 47/188 (25%), Positives = 75/188 (39%), Gaps = 20/188 (10%)
Query: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
S+ C C P + + G+ +HE CF+C+ C Q F +G YC ++
Sbjct: 98 SSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENK 157
Query: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
FAP C +C + + + + WH EC C CQ LA F C C
Sbjct: 158 FAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVAC----- 212
Query: 127 ARGLGKYICQKCHAIIDEQPLI---------FKNDPYHPDHFNCANCGKELTADARELKG 177
G+ KC + ++P++ F++ +H + F+CA C L G
Sbjct: 213 ---FGELFAPKCSSC--KRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDG 267
Query: 178 -ELYCLPC 184
++ C C
Sbjct: 268 DQVLCQGC 275
>gi|15743548 LIM and senescent cell antigen-like domains 3 [Homo
sapiens]
Length = 117
Score = 113 bits (282), Expect = 3e-25
Identities = 51/52 (98%), Positives = 51/52 (98%)
Query: 1 MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYE 52
MANALASATCERCKGGFAPAE IVNSNGELYHEQCFVCAQCFQQFPEGLFYE
Sbjct: 63 MANALASATCERCKGGFAPAETIVNSNGELYHEQCFVCAQCFQQFPEGLFYE 114
Score = 29.3 bits (64), Expect = 5.0
Identities = 12/32 (37%), Positives = 20/32 (62%)
Query: 204 VVNAMGKQWHVEHFVCAKCEKPFLGHRHYERK 235
+VN+ G+ +H + FVCA+C + F YE +
Sbjct: 85 IVNSNGELYHEQCFVCAQCFQQFPEGLFYEER 116
>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
Length = 746
Score = 111 bits (277), Expect = 1e-24
Identities = 69/227 (30%), Positives = 99/227 (43%), Gaps = 17/227 (7%)
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 130
CH+CGE G V++ +H +CF C +C LA GF G +LC + R
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR- 97
Query: 131 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANC------GKELTADARELKGELYCLPC 184
C C ++ + + YHP+ F C C G +T + R+ +L P
Sbjct: 98 ----CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPM 153
Query: 185 HDKMGVPI----CGACRRPIE-GRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAY 239
C C R I+ G+ + A+ KQWH+ F C C K G + + G Y
Sbjct: 154 SSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPY 212
Query: 240 CETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLT 286
CE Y LFG C C++ I G V+ A +K + +C CS CN T
Sbjct: 213 CEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFT 259
Score = 107 bits (267), Expect = 1e-23
Identities = 63/221 (28%), Positives = 98/221 (44%), Gaps = 11/221 (4%)
Query: 11 ERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPC 70
E CKG +++ + +H +CF C C +G F+ G C D+Q ++
Sbjct: 44 EPCKG------EVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTR 97
Query: 71 CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRH-LCRPCHNREKARG 129
CH CGEF+ G V+ A+ ++HP CF C +C+ V GR LC+ C +
Sbjct: 98 CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 157
Query: 130 LGKYICQKC----HAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCH 185
C I + Q L+ + +H F C +CGK LT + G YC +
Sbjct: 158 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDY 217
Query: 186 DKMGVPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPF 226
+ C AC + I G+V+ A K +H C++C + F
Sbjct: 218 QGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMF 258
Score = 64.3 bits (155), Expect = 1e-10
Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
S+ C C + ++ + + +H CF C C + G + +G YCE D+Q L
Sbjct: 163 SSNCAGCGRDIKNGQALLALDKQ-WHLGCFKCKSCGKVLT-GEYISKDGAPYCEKDYQGL 220
Query: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLAD 106
F C C +FI G+V++A + +HP C RC C ++ +
Sbjct: 221 FGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTE 260
Score = 30.0 bits (66), Expect = 2.9
Identities = 11/42 (26%), Positives = 18/42 (42%)
Query: 252 CFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVE 293
C C +G+V+ K + + CF C C L F++
Sbjct: 39 CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIK 80
Score = 29.6 bits (65), Expect = 3.8
Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 2/44 (4%)
Query: 5 LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEG 48
L CE C K++ + + YH C C++C Q F EG
Sbjct: 220 LFGVKCEACHQFITG--KVLEAGDKHYHPSCARCSRCNQMFTEG 261
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.142 0.492
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,999,848
Number of Sequences: 37866
Number of extensions: 699243
Number of successful extensions: 4423
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 220
Number of HSP's that attempted gapping in prelim test: 2678
Number of HSP's gapped (non-prelim): 1062
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.