Guide to the Human Genome
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Search of human proteins with 61175248

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61175248 spermidine/spermine N1-acetyl transferase-like 1
[Homo sapiens]
         (445 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61175248 spermidine/spermine N1-acetyl transferase-like 1 [Ho...   920   0.0  
gi|14149793 glutamine rich 2 [Homo sapiens]                           164   2e-40
gi|4506789 diamine N-acetyltransferase 1 [Homo sapiens]               115   8e-26
gi|150170670 piccolo isoform 2 [Homo sapiens]                         103   4e-22
gi|150378539 piccolo isoform 1 [Homo sapiens]                         103   4e-22
gi|19424126 diamine N-acetyltransferase 2 [Homo sapiens]               97   2e-20
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     62   8e-10
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     62   8e-10
gi|119943102 CREB binding protein isoform b [Homo sapiens]             62   1e-09
gi|119943104 CREB binding protein isoform a [Homo sapiens]             62   1e-09
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    57   4e-08
gi|56117844 synovial sarcoma translocation, chromosome 18 isofor...    54   3e-07
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      54   4e-07
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    51   2e-06
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    51   2e-06
gi|56117846 synovial sarcoma translocation, chromosome 18 isofor...    50   3e-06
gi|50345997 E1A binding protein p300 [Homo sapiens]                    50   5e-06
gi|38788274 bromodomain PHD finger transcription factor isoform ...    50   5e-06
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       49   7e-06
gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]      48   2e-05
gi|219802034 nuclear factor related to kappaB binding protein is...    47   3e-05
gi|23346420 nuclear factor related to kappaB binding protein iso...    47   3e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     47   3e-05
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       46   6e-05
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       46   6e-05
gi|38788260 bromodomain PHD finger transcription factor isoform ...    46   8e-05
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                45   1e-04
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]           45   1e-04
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]           45   1e-04
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 45   2e-04

>gi|61175248 spermidine/spermine N1-acetyl transferase-like 1 [Homo
           sapiens]
          Length = 445

 Score =  920 bits (2379), Expect = 0.0
 Identities = 445/445 (100%), Positives = 445/445 (100%)

Query: 1   MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD 60
           MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD
Sbjct: 1   MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD 60

Query: 61  ANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTN 120
           ANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTN
Sbjct: 61  ANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTN 120

Query: 121 LPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTS 180
           LPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTS
Sbjct: 121 LPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTS 180

Query: 181 QAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPR 240
           QAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPR
Sbjct: 181 QAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPR 240

Query: 241 QPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPS 300
           QPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPS
Sbjct: 241 QPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPS 300

Query: 301 QPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQTSMDYFQIRHAEAGDCPEILRLIK 360
           QPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQTSMDYFQIRHAEAGDCPEILRLIK
Sbjct: 301 QPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQTSMDYFQIRHAEAGDCPEILRLIK 360

Query: 361 ELAACENMLDAMELTAADLLRDGFGDNPLFYCLIAEVNDQQKPSGKLTVGFAMYYFTYDS 420
           ELAACENMLDAMELTAADLLRDGFGDNPLFYCLIAEVNDQQKPSGKLTVGFAMYYFTYDS
Sbjct: 361 ELAACENMLDAMELTAADLLRDGFGDNPLFYCLIAEVNDQQKPSGKLTVGFAMYYFTYDS 420

Query: 421 WTGKVLYLEDFYVTQAYQDSHHNSM 445
           WTGKVLYLEDFYVTQAYQDSHHNSM
Sbjct: 421 WTGKVLYLEDFYVTQAYQDSHHNSM 445


>gi|14149793 glutamine rich 2 [Homo sapiens]
          Length = 1663

 Score =  164 bits (415), Expect = 2e-40
 Identities = 125/357 (35%), Positives = 159/357 (44%), Gaps = 13/357 (3%)

Query: 1   MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD 60
           M   G+ QPG  Q G+ Q      D+ Q G  Q V  QPG+ QP   Q  + Q  + QP 
Sbjct: 459 MDQSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPG 518

Query: 61  ANQSSLSD--SNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGM---- 114
           A Q  L    ++Q  ++QP     G+ Q   +Q   +     Q  + QP + Q G+    
Sbjct: 519 AYQPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPR 578

Query: 115 --RQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQS 172
              Q G   P  +Q G+ QPG  Q G  QPG+    L++    + S+ QPG  QR   Q 
Sbjct: 579 ADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQP 638

Query: 173 GPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQT 232
           G  Q    Q G  Q G+ QP      + Q G  QP   Q G  Q G  Q G+ QPG  Q 
Sbjct: 639 GAVQRGLVQPGAVQRGLVQP-----GVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQR 693

Query: 233 GLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQP 292
           GL QP   Q     PG+ QRG+ QPGM Q+   Q G  QPG  Q    Q GM  PG GQ 
Sbjct: 694 GLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGIGQQ 753

Query: 293 GIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQTSMDYFQIRHAEA 349
           G+ +P     GL Q     L L QPG      SQ      G+ Q  MD + +R   A
Sbjct: 754 GMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGMDQYGLRQPGA 810



 Score =  130 bits (327), Expect = 2e-30
 Identities = 113/368 (30%), Positives = 154/368 (41%), Gaps = 39/368 (10%)

Query: 1   MSPPGMWQPG----------VQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSC 50
           + P GM QPG          V    + Q     P+M    +   V  +  +  P  S   
Sbjct: 226 LEPTGMNQPGLVPASTYPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPP--SVPG 283

Query: 51  KNQTDMSQPDANQSSLSDSN--QTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPS 108
           ++Q  +  P  +Q  L   +  Q G+  P      M  + M+Q    +  M Q  +  P 
Sbjct: 284 RDQQGLELPSTDQHGLVSVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPP- 342

Query: 109 MSQAGMRQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASIS-----QPG 163
               G+ Q G  LP ++Q G+  P T Q G   PG+ P S  +    + S+      QPG
Sbjct: 343 ----GIDQQGLTLPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPG 398

Query: 164 PPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIG 223
             Q    QSG  Q +  Q G  Q G+ QP        Q G  +P M Q G +Q G  Q G
Sbjct: 399 TEQHDLIQSGRFQRALVQRGAYQPGLVQP-----GADQRGLVRPGMDQSGLAQPGADQRG 453

Query: 224 MSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTG 283
           +  PG  Q+GL+QP   Q     PG  Q  + Q G  Q V  Q G+ QPG  Q  + Q  
Sbjct: 454 LVWPGMDQSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRA 513

Query: 284 MSHPGRGQPG----------IWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMG 333
           +  PG  QPG          + +PG  Q GL Q   +Q  L+QPG  Q G  QP V Q G
Sbjct: 514 LVQPGAYQPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRG 573

Query: 334 MRQTSMDY 341
           + Q   D+
Sbjct: 574 LAQPRADH 581



 Score =  127 bits (318), Expect = 3e-29
 Identities = 105/338 (31%), Positives = 142/338 (42%), Gaps = 19/338 (5%)

Query: 14  PGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSDSNQTG 73
           PG  QQ    P   Q G+      Q G+  P T Q       M Q       +S   Q G
Sbjct: 282 PGRDQQGLELPSTDQHGLVSVSAYQHGMTFPGTDQRSMEPLGMDQRGC---VISGMGQQG 338

Query: 74  IIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQPGMKQPG 133
           ++ P     G+    ++Q    L   +Q  +  P +      Q G   P +   G  QPG
Sbjct: 339 LVPPGIDQQGLTLPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPG 398

Query: 134 TWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTSQAGTNQ------- 186
           T Q    Q G + ++L +    +  + QPG  QR   + G  QS  +Q G +Q       
Sbjct: 399 TEQHDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPG 458

Query: 187 ---SGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPN 243
              SG++QP        Q G  QP   Q    QSGT Q  + QPG  Q G+ QP   Q  
Sbjct: 459 MDQSGLAQP-----GRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRA 513

Query: 244 KSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPG 303
              PG +Q G+ QPG  Q    Q G  Q G  QS  +Q+ ++ PG  Q G+ +PG  Q G
Sbjct: 514 LVQPGAYQPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRG 573

Query: 304 LSQQDL-NQLVLSQPGLSQPGRSQPSVSQMGMRQTSMD 340
           L+Q    +Q  L  PG  Q G  QP   Q G+ Q  +D
Sbjct: 574 LAQPRADHQRGLVPPGADQRGLVQPGADQHGLVQPGVD 611



 Score =  127 bits (318), Expect = 3e-29
 Identities = 117/412 (28%), Positives = 159/412 (38%), Gaps = 65/412 (15%)

Query: 4   PGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQ 63
           PG +QPG+ QPG  Q      D+ QPG  Q    Q G  Q D +Q    Q  + QP  +Q
Sbjct: 517 PGAYQPGLVQPGADQI-----DVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQ 571

Query: 64  SSLSD-------------SNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMS 110
             L+              ++Q G++QP     G+ Q  ++Q   +     Q  + QP + 
Sbjct: 572 RGLAQPRADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHGLAQPGEVQRSLVQPGIV 631

Query: 111 QAGMRQSGTNLPDINQPG-----MKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPP 165
           Q G+ Q G     + QPG     + QPG  Q G  QPG   + L +    +  + QPG  
Sbjct: 632 QRGLVQPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGAD 691

Query: 166 QRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIG-- 223
           QR   Q G  Q    Q G +Q G+ QP M Q  + Q G  QP + Q G  Q G  Q G  
Sbjct: 692 QRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGIG 751

Query: 224 ---------------------------------MSQPGTWQTGLSQPVPRQPNKSPPGMW 250
                                            +SQ GT+  GL QP   Q     PG +
Sbjct: 752 QQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGMDQYGLRQPGAY 811

Query: 251 QRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEP-----GPSQPGLS 305
           Q G+  PG   +  S       G       Q GM  PGR Q G   P     G + PG+ 
Sbjct: 812 QPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGREQYGQVSPLLASQGLASPGID 871

Query: 306 QQDLNQLVLSQPGLSQPGRSQ--PSVSQMGMRQTSMDYFQIRHAEAGDCPEI 355
           ++ L      Q GL  PG  Q  P     G+  T  D   +     G+  ++
Sbjct: 872 RRSLVPPETYQQGLMHPGTDQHSPIPLSTGLGSTHPDQQHVASPGPGEHDQV 923



 Score =  112 bits (279), Expect = 9e-25
 Identities = 104/354 (29%), Positives = 147/354 (41%), Gaps = 47/354 (13%)

Query: 27  SQPGMSQQVPSQPGIR-QPDTSQSCKNQTDMSQPDANQSSLSDSNQTGIIQPSPSLLGMN 85
           ++PG  QQ    P  R QP +  + ++Q  + +PD      +  NQ G++  S    G+ 
Sbjct: 191 ARPGPVQQ--DLPLARDQPSSVPASQSQVHL-RPDRRGLEPTGMNQPGLVPASTYPHGVV 247

Query: 86  QMDMNQWSASLYEMNQVDM--------KQPSMSQAGMRQSGTNLPDINQPGMKQPGTWQL 137
            + M Q      EM+  ++        +    S  G  Q G  LP  +Q G+     +Q 
Sbjct: 248 PLSMGQLGVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHGLVSVSAYQH 307

Query: 138 GRSQPGMWPQSLSELVLSE-----ASISQPGPPQRAPSQSGPRQSSTSQAG-----TNQS 187
           G + PG   +S+  L + +     + + Q G       Q G       Q G     T+Q 
Sbjct: 308 GMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLTLPVVDQHGLVLPFTDQH 367

Query: 188 GISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPG----------TWQTGLSQP 237
           G+  P +  +   Q G  QPS+   G  Q GT Q  + Q G           +Q GL QP
Sbjct: 368 GLVSPGLMPISADQQGFVQPSLEATGFIQPGTEQHDLIQSGRFQRALVQRGAYQPGLVQP 427

Query: 238 VPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRG------- 290
              Q     PGM Q G+ QPG  Q+     GM Q G +Q  ++Q G+  PG G       
Sbjct: 428 GADQRGLVRPGMDQSGLAQPGADQRGLVWPGMDQSGLAQPGRDQHGLIQPGTGQHDLVQS 487

Query: 291 --------QPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQ 336
                   QPG+ +PG  QPG  Q+ L Q    QPGL QPG  Q  V Q G  Q
Sbjct: 488 GTGQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGADQ 541



 Score = 33.9 bits (76), Expect = 0.31
 Identities = 43/183 (23%), Positives = 66/183 (36%), Gaps = 21/183 (11%)

Query: 4   PGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQ-----SCKNQTDMSQ 58
           PG +QPG+  PG   +  S       G     P Q G+  P   Q            ++ 
Sbjct: 808 PGAYQPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGREQYGQVSPLLASQGLAS 867

Query: 59  PDANQSSL--SDSNQTGIIQPS-------PSLLGMNQMDMNQWSASLYEMNQVDMKQPSM 109
           P  ++ SL   ++ Q G++ P        P   G+     +Q   +     + D   P  
Sbjct: 868 PGIDRRSLVPPETYQQGLMHPGTDQHSPIPLSTGLGSTHPDQQHVASPGPGEHDQVYPDA 927

Query: 110 SQAGMRQSGTNLPDINQPGMKQPGTWQLGR-SQPGMWPQSLSELVLSEASISQPGPPQRA 168
           +Q G   S  +  D   PG + PG     +  Q G+ P        + AS     P Q+A
Sbjct: 928 AQHGHAFSLFDSHDSMYPGYRGPGYLSADQHGQEGLDPNR------TRASDRHGIPAQKA 981

Query: 169 PSQ 171
           P Q
Sbjct: 982 PGQ 984


>gi|4506789 diamine N-acetyltransferase 1 [Homo sapiens]
          Length = 171

 Score =  115 bits (288), Expect = 8e-26
 Identities = 58/101 (57%), Positives = 70/101 (69%), Gaps = 1/101 (0%)

Query: 339 MDYFQIRHAEAGDCPEILRLIKELAACENMLDAMELTAADLLRDGFGDNPLFYCLIAEV- 397
           M  F IR A A DC +ILRLIKELA  E M + + LT  DLL DGFG++P ++CL+AEV 
Sbjct: 1   MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVP 60

Query: 398 NDQQKPSGKLTVGFAMYYFTYDSWTGKVLYLEDFYVTQAYQ 438
            +   P G   VGFAMYYFTYD W GK+LYLEDF+V   Y+
Sbjct: 61  KEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYR 101


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score =  103 bits (256), Expect = 4e-22
 Identities = 99/363 (27%), Positives = 153/363 (42%), Gaps = 46/363 (12%)

Query: 3   PPGMWQPGVQQ----PGISQQVPSHPDMSQPGMSQQVPSQ---------PGIRQPDTSQS 49
           P G+ +P +QQ    P   QQ P    + Q G  + + SQ         PG  +P    +
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262

Query: 50  CKNQTDMSQ-PDANQSSLSDSNQTGIIQ--------PSPSLLGMNQMDMNQWSASL--YE 98
              QTD ++ P    +S   + Q  I++        PSPS   + Q    +  A    +E
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322

Query: 99  MNQVDMKQPSMSQAGM-----RQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELV 153
            +Q    +P    +G+     +Q GT  P +  PG  +P    LG ++P    Q+ SE  
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA-QQTGSEKP 381

Query: 154 LSEA----SISQPGPPQRAPSQS-GPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPS 208
            SE     +++QP    + P+Q  GP +  T Q GT +    QP +      QS    P 
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL------QSPAKAPG 435

Query: 209 MRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLG 268
             +    Q G  +I   Q G  +T   Q  P +P    PG  +    QPG ++  P    
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP---- 491

Query: 269 MRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPS 328
            +QPG+++    Q G + P   QPG  +P P QPG ++    Q   ++P   QP  ++PS
Sbjct: 492 -QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550

Query: 329 VSQ 331
             Q
Sbjct: 551 AQQ 553



 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 79/294 (26%), Positives = 126/294 (42%), Gaps = 22/294 (7%)

Query: 21  PSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSD--SNQTGIIQPS 78
           PS P  S+P + Q  P +P  +QP      K+Q   ++P A  S L+   + Q G ++P 
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHE---KSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352

Query: 79  PSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQ----SGTNLPDINQPGMKQPGT 134
               G  +        +     Q   ++PS  Q G +      G       QPG  +P T
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412

Query: 135 WQLGRSQPGMWPQSLSELVLS----EASISQPGPPQRAPSQSGPRQSSTSQAGTNQSGIS 190
            Q+G  +P      L     +    +  + QPGP +    Q+GP ++S  Q G  +    
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472

Query: 191 QPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMW 250
            P   +   +Q G ++P  +Q G+++  + Q G ++P   Q G ++P P+QP  + P   
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532

Query: 251 QRGMWQPGMSQQVPSQLGMRQPGTSQSSK--NQTGMSHPGRGQPGIWEPGPSQP 302
           Q G  +P   Q  P+     +P   QS+K  +QTG   P   QP    P   QP
Sbjct: 533 QPGSAKPSAQQPSPA-----KPSAQQSTKPVSQTGSGKP--LQPPTVSPSAKQP 579



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 44/184 (23%), Positives = 77/184 (41%), Gaps = 15/184 (8%)

Query: 161 QPGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTS 220
           Q  PP+  P Q GP +    Q GT +S IS     ++  +  G  +P      T Q+  +
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKS-ISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270

Query: 221 QIGM----SQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQ 276
           ++ +    S+P T Q  + +    +P+   P        +P + Q  P +   +QPG   
Sbjct: 271 KLPLQRDASRPQTKQADIVRGESVKPSLPSPS-------KPPIQQPTPGKPPAQQPG--- 320

Query: 277 SSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQ 336
             K+Q G + P     G+ +P   QPG  +  +     ++P     G ++P   Q G  +
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 337 TSMD 340
            S +
Sbjct: 381 PSSE 384



 Score = 33.1 bits (74), Expect = 0.52
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 7/58 (12%)

Query: 4   PGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCK--NQTDMSQP 59
           PG  +P  QQPG ++     P   QPG ++    QP   +P   QS K  +QT   +P
Sbjct: 514 PGPAKPSPQQPGSTK-----PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score =  103 bits (256), Expect = 4e-22
 Identities = 99/363 (27%), Positives = 153/363 (42%), Gaps = 46/363 (12%)

Query: 3   PPGMWQPGVQQ----PGISQQVPSHPDMSQPGMSQQVPSQ---------PGIRQPDTSQS 49
           P G+ +P +QQ    P   QQ P    + Q G  + + SQ         PG  +P    +
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPT 262

Query: 50  CKNQTDMSQ-PDANQSSLSDSNQTGIIQ--------PSPSLLGMNQMDMNQWSASL--YE 98
              QTD ++ P    +S   + Q  I++        PSPS   + Q    +  A    +E
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322

Query: 99  MNQVDMKQPSMSQAGM-----RQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELV 153
            +Q    +P    +G+     +Q GT  P +  PG  +P    LG ++P    Q+ SE  
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA-QQTGSEKP 381

Query: 154 LSEA----SISQPGPPQRAPSQS-GPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPS 208
            SE     +++QP    + P+Q  GP +  T Q GT +    QP +      QS    P 
Sbjct: 382 SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL------QSPAKAPG 435

Query: 209 MRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLG 268
             +    Q G  +I   Q G  +T   Q  P +P    PG  +    QPG ++  P    
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP---- 491

Query: 269 MRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPS 328
            +QPG+++    Q G + P   QPG  +P P QPG ++    Q   ++P   QP  ++PS
Sbjct: 492 -QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550

Query: 329 VSQ 331
             Q
Sbjct: 551 AQQ 553



 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 79/294 (26%), Positives = 126/294 (42%), Gaps = 22/294 (7%)

Query: 21  PSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSD--SNQTGIIQPS 78
           PS P  S+P + Q  P +P  +QP      K+Q   ++P A  S L+   + Q G ++P 
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHE---KSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352

Query: 79  PSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQ----SGTNLPDINQPGMKQPGT 134
               G  +        +     Q   ++PS  Q G +      G       QPG  +P T
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412

Query: 135 WQLGRSQPGMWPQSLSELVLS----EASISQPGPPQRAPSQSGPRQSSTSQAGTNQSGIS 190
            Q+G  +P      L     +    +  + QPGP +    Q+GP ++S  Q G  +    
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472

Query: 191 QPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMW 250
            P   +   +Q G ++P  +Q G+++  + Q G ++P   Q G ++P P+QP  + P   
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532

Query: 251 QRGMWQPGMSQQVPSQLGMRQPGTSQSSK--NQTGMSHPGRGQPGIWEPGPSQP 302
           Q G  +P   Q  P+     +P   QS+K  +QTG   P   QP    P   QP
Sbjct: 533 QPGSAKPSAQQPSPA-----KPSAQQSTKPVSQTGSGKP--LQPPTVSPSAKQP 579



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 44/184 (23%), Positives = 77/184 (41%), Gaps = 15/184 (8%)

Query: 161 QPGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTS 220
           Q  PP+  P Q GP +    Q GT +S IS     ++  +  G  +P      T Q+  +
Sbjct: 212 QQQPPKPIPKQQGPGRDPLQQDGTPKS-ISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270

Query: 221 QIGM----SQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQ 276
           ++ +    S+P T Q  + +    +P+   P        +P + Q  P +   +QPG   
Sbjct: 271 KLPLQRDASRPQTKQADIVRGESVKPSLPSPS-------KPPIQQPTPGKPPAQQPG--- 320

Query: 277 SSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQ 336
             K+Q G + P     G+ +P   QPG  +  +     ++P     G ++P   Q G  +
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 337 TSMD 340
            S +
Sbjct: 381 PSSE 384



 Score = 33.1 bits (74), Expect = 0.52
 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 7/58 (12%)

Query: 4   PGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCK--NQTDMSQP 59
           PG  +P  QQPG ++     P   QPG ++    QP   +P   QS K  +QT   +P
Sbjct: 514 PGPAKPSPQQPGSTK-----PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKP 566


>gi|19424126 diamine N-acetyltransferase 2 [Homo sapiens]
          Length = 170

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 45/97 (46%), Positives = 64/97 (65%), Gaps = 1/97 (1%)

Query: 343 QIRHAEAGDCPEILRLIKELAACENMLDAMELTAADLLRDGFGDNPLFYCLIAEVNDQQ- 401
           +IR A+ GDC +ILRLI+ELA  E + D ++++   L  DGFGDNP ++CL+AE+     
Sbjct: 5   RIREAKEGDCGDILRLIRELAEFEKLSDQVKISEEALRADGFGDNPFYHCLVAEILPAPG 64

Query: 402 KPSGKLTVGFAMYYFTYDSWTGKVLYLEDFYVTQAYQ 438
           K  G   VG+ +YYF Y +W G+ +YLED YV   Y+
Sbjct: 65  KLLGPCVVGYGIYYFIYSTWKGRTIYLEDIYVMPEYR 101


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 98/347 (28%), Positives = 128/347 (36%), Gaps = 39/347 (11%)

Query: 3   PPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDAN 62
           P G  Q G Q P  +QQ P HP   QP  SQQ PSQ    QP   Q        SQP   
Sbjct: 459 PSGYGQQG-QTPYYNQQSP-HPQQQQPPYSQQPPSQTPHAQPSYQQQ-----PQSQPPQL 511

Query: 63  QSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLP 122
           QSS    +Q    QPS           +Q S + Y   Q   +Q   SQ    Q     P
Sbjct: 512 QSSQPPYSQ----QPS--------QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP 559

Query: 123 -DINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQ-SGPRQSSTS 180
               QP    P T     SQ   +PQ  S+     A   Q  PP +  SQ S   Q+S++
Sbjct: 560 YQQQQPQQPAPST----LSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSA 615

Query: 181 QAGTNQSGISQPVMWQLDMRQSGGSQPSMR-QVGTSQSGTSQIGMSQPGTWQTGLSQPVP 239
            + T+  G  + +   L  R S  S P +   +     GT   G   PG   +G+S    
Sbjct: 616 PSMTSSKGGQEDMNLSLQSRPS--SLPDLSGSIDDLPMGTE--GALSPGVSTSGISSSQG 671

Query: 240 RQPNKS-PPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPG 298
            Q N +  P         PG+    PS +G         S   +  + PG   P     G
Sbjct: 672 EQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG 731

Query: 299 PS----QPGLSQQDLNQ---LVLSQPGLSQPGRSQPSVSQMGMRQTS 338
            S     P ++Q  + Q    +   P + Q    QP  S +  RQ S
Sbjct: 732 QSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPG-SALSPRQPS 777



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 73/289 (25%), Positives = 102/289 (35%), Gaps = 52/289 (17%)

Query: 105 KQPSMSQAGMRQSGTNLPD--INQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASI--- 159
           K P  S A    S ++         G   P     G  QP   P +L++L+ S +S    
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP-TLNQLLTSPSSARGY 308

Query: 160 ------SQPGPPQRAPSQSGPRQ--------SSTSQAGTNQSGISQPVMWQLDMR---QS 202
                    G PQ   +  GP          ++ + A    SG +Q       M      
Sbjct: 309 QGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSG 368

Query: 203 GGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGM--S 260
           GG QP  R    S S   Q+G  +P  +  G + P  +Q  + PP   Q+G   PG    
Sbjct: 369 GGGQPLARTPQPS-SPMDQMGKMRPQPY--GGTNPYSQQ--QGPPSGPQQGHGYPGQPYG 423

Query: 261 QQVPSQLGMRQPGTSQSSKNQTGMSHP------------GRGQPGIW--------EPGPS 300
            Q P +  M   G +QS+    G+S+             G GQ G           P   
Sbjct: 424 SQTPQRYPMTMQGRAQSAMG--GLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQ 481

Query: 301 QPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQTSMDYFQIRHAEA 349
           QP  SQQ  +Q   +QP   Q  +SQP   Q      S    Q  H ++
Sbjct: 482 QPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQS 530



 Score = 37.0 bits (84), Expect = 0.036
 Identities = 69/311 (22%), Positives = 103/311 (33%), Gaps = 77/311 (24%)

Query: 1    MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD 60
            + P G    G  QP +   +PS+PD      S+  P Q   +Q     S  NQ       
Sbjct: 1294 IGPEGNMSTGAPQPNL---MPSNPDSGMYSPSRYPPQQQQ-QQQQRHDSYGNQF------ 1343

Query: 61   ANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAG---MRQS 117
            + Q + S S       P PS              ++Y+  Q + K+P     G    R  
Sbjct: 1344 STQGTPSGS-------PFPSQ-----------QTTMYQQQQQNYKRPMDGTYGPPAKRHE 1385

Query: 118  GTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQS 177
            G         G  QP   QL  +QP            S+   +QP P Q   +Q G    
Sbjct: 1386 GEMYSVPYSTGQGQPQQQQLPPAQPQP---------ASQQQAAQPSPQQDVYNQYGNAYP 1436

Query: 178  STSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQP 237
            +T+ A T             + R +GG Q         Q G  ++  + PGT        
Sbjct: 1437 ATATAAT-------------ERRPAGGPQNQF----PFQFGRDRVS-APPGT-------- 1470

Query: 238  VPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEP 297
                    PP M         M   + +   + Q GT    +N    ++  R   G    
Sbjct: 1471 --NAQQNMPPQM---------MGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQ 1519

Query: 298  GPSQPGLSQQD 308
            GP+  G+++ D
Sbjct: 1520 GPAYHGVNRTD 1530


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 98/347 (28%), Positives = 128/347 (36%), Gaps = 39/347 (11%)

Query: 3   PPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDAN 62
           P G  Q G Q P  +QQ P HP   QP  SQQ PSQ    QP   Q        SQP   
Sbjct: 459 PSGYGQQG-QTPYYNQQSP-HPQQQQPPYSQQPPSQTPHAQPSYQQQ-----PQSQPPQL 511

Query: 63  QSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLP 122
           QSS    +Q    QPS           +Q S + Y   Q   +Q   SQ    Q     P
Sbjct: 512 QSSQPPYSQ----QPS--------QPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP 559

Query: 123 -DINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQ-SGPRQSSTS 180
               QP    P T     SQ   +PQ  S+     A   Q  PP +  SQ S   Q+S++
Sbjct: 560 YQQQQPQQPAPST----LSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSA 615

Query: 181 QAGTNQSGISQPVMWQLDMRQSGGSQPSMR-QVGTSQSGTSQIGMSQPGTWQTGLSQPVP 239
            + T+  G  + +   L  R S  S P +   +     GT   G   PG   +G+S    
Sbjct: 616 PSMTSSKGGQEDMNLSLQSRPS--SLPDLSGSIDDLPMGTE--GALSPGVSTSGISSSQG 671

Query: 240 RQPNKS-PPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPG 298
            Q N +  P         PG+    PS +G         S   +  + PG   P     G
Sbjct: 672 EQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSG 731

Query: 299 PS----QPGLSQQDLNQ---LVLSQPGLSQPGRSQPSVSQMGMRQTS 338
            S     P ++Q  + Q    +   P + Q    QP  S +  RQ S
Sbjct: 732 QSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPG-SALSPRQPS 777



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 73/289 (25%), Positives = 102/289 (35%), Gaps = 52/289 (17%)

Query: 105 KQPSMSQAGMRQSGTNLPD--INQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASI--- 159
           K P  S A    S ++         G   P     G  QP   P +L++L+ S +S    
Sbjct: 250 KPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATP-TLNQLLTSPSSARGY 308

Query: 160 ------SQPGPPQRAPSQSGPRQ--------SSTSQAGTNQSGISQPVMWQLDMR---QS 202
                    G PQ   +  GP          ++ + A    SG +Q       M      
Sbjct: 309 QGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSG 368

Query: 203 GGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGM--S 260
           GG QP  R    S S   Q+G  +P  +  G + P  +Q  + PP   Q+G   PG    
Sbjct: 369 GGGQPLARTPQPS-SPMDQMGKMRPQPY--GGTNPYSQQ--QGPPSGPQQGHGYPGQPYG 423

Query: 261 QQVPSQLGMRQPGTSQSSKNQTGMSHP------------GRGQPGIW--------EPGPS 300
            Q P +  M   G +QS+    G+S+             G GQ G           P   
Sbjct: 424 SQTPQRYPMTMQGRAQSAMG--GLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQ 481

Query: 301 QPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQTSMDYFQIRHAEA 349
           QP  SQQ  +Q   +QP   Q  +SQP   Q      S    Q  H ++
Sbjct: 482 QPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQS 530


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 96/363 (26%), Positives = 135/363 (37%), Gaps = 62/363 (17%)

Query: 5    GMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQ------------PGIRQPDTSQSCKN 52
            GM  PG Q   +S  VP    +S P M    P Q            PG+ +P  S   + 
Sbjct: 1949 GMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQA 2008

Query: 53   QTDMSQPDANQ--SSLSDSNQTGIIQ--PSPSLLGMNQMDMNQWSASLYEMNQVDMKQPS 108
                 +  + Q   S+S S    +++   SPS     Q  +N           +    P 
Sbjct: 2009 AVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLN-----------ILKSNPQ 2057

Query: 109  MSQAGMRQSGTNLPDINQPGMK-QPGTWQLGRSQPGMWPQ-------SLSELVLSEASIS 160
            +  A ++Q  T     NQPGM+ QPG     +SQPGM PQ       SL  L   +A + 
Sbjct: 2058 LMAAFIKQR-TAKYVANQPGMQPQPGL----QSQPGMQPQPGMHQQPSLQNLNAMQAGVP 2112

Query: 161  QPGPPQRAPSQSGPRQSSTS----QAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQ 216
            +PG P +  +  G      +      G N +  S    ++  +R+    Q   +Q    Q
Sbjct: 2113 RPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQ 2172

Query: 217  SGTSQIGMSQPGTWQTGLSQ-PVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTS 275
                Q G +       G  Q   P+ P   PP M Q    Q  M Q +P Q      G  
Sbjct: 2173 QQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQ----QQRMQQHLPLQ--GSSMGQM 2226

Query: 276  QSSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQ----PGRSQPSVSQ 331
             +   Q G      GQPG+     S P + QQ L Q +L Q  + Q    PG+  P   Q
Sbjct: 2227 AAQMGQLGQ----MGQPGL--GADSTPNI-QQALQQRILQQQQMKQQIGSPGQPNPMSPQ 2279

Query: 332  MGM 334
              M
Sbjct: 2280 QHM 2282



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 92/354 (25%), Positives = 131/354 (37%), Gaps = 54/354 (15%)

Query: 18   QQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMS----------QPDANQSSLS 67
            Q +PS P  + PG   Q PS P   QP  +Q   +   MS          QP    S+  
Sbjct: 1842 QSLPS-PTSAPPGTPTQQPSTPQTPQP-PAQPQPSPVSMSPAGFPSVARTQPPTTVSTGK 1899

Query: 68   DSNQTGI----IQPSPSLL-GMNQMDMN-QWSASLYEMNQVDMKQPSMSQAG-----MRQ 116
             ++Q        QP P+ +    Q++   Q    LY +N  +   P  +  G     M  
Sbjct: 1900 PTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAP 1959

Query: 117  SGTNLPDINQ------PGMKQPGTWQ---LGRSQPGMWPQSLSELVLSEASISQPGPPQR 167
               N+P  NQ      P M  PG WQ   L + QP   P     ++  +A  +  GP  R
Sbjct: 1960 VSLNVPRPNQVSGPVMPSM-PPGQWQQAPLPQQQP--MPGLPRPVISMQAQAAVAGP--R 2014

Query: 168  APSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSG--GSQPSMRQVGTSQSGTSQIGMS 225
             PS   PR  S S        +  P   Q   +      S P +      Q  T++   +
Sbjct: 2015 MPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQR-TAKYVAN 2073

Query: 226  QPGTW-QTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGM 284
            QPG   Q GL      QP    PGM Q    QP +      Q G+ +PG     +   G+
Sbjct: 2074 QPGMQPQPGLQSQPGMQPQ---PGMHQ----QPSLQNLNAMQAGVPRPGVPPQQQAMGGL 2126

Query: 285  SHPGRGQPGIWEPG--PSQPGLSQQ---DLNQLVLSQPGLSQPGRSQPSVSQMG 333
            +  G+    I  PG  P+   ++ Q    L + +L Q    Q  + Q    Q G
Sbjct: 2127 NPQGQAL-NIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQG 2179



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 92/367 (25%), Positives = 134/367 (36%), Gaps = 79/367 (21%)

Query: 4   PGMWQPGVQQPGISQQVPSHP---DMSQP--------GMSQQVPSQPG-IRQPDTSQSCK 51
           P +  PG Q P I Q  P  P    +S P        GM+   P   G ++ P      +
Sbjct: 645 PALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPR 704

Query: 52  NQTDMSQPDANQSSLSDSNQTGIIQPS-----PSLLGMNQMDM-------------NQWS 93
             + M+   + Q +   S     I PS     P+++G +  +M             NQ+ 
Sbjct: 705 AASPMNH--SVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFP 762

Query: 94  ASLYEMNQVDMKQPSMSQAGMRQS---GTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLS 150
           +S   M+ V M QP  +Q G+ Q    G  LP  N   M  P   QL        P   +
Sbjct: 763 SSSGAMS-VGMGQPP-AQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLHPT 818

Query: 151 ELVLSEA----SISQPGPPQRAPSQ-SGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGS 205
               S A    S+    PP   P Q + P Q ST  + + Q+    P           GS
Sbjct: 819 PPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTP-----------GS 867

Query: 206 QPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPS 265
            PS  Q  T  + T Q       T       P P+ P + P       +  P  SQQ P+
Sbjct: 868 VPSATQ--TQSTPTVQAAAQAQVT-------PQPQTPVQPP------SVATPQSSQQQPT 912

Query: 266 QLGMRQPGT--SQSSKNQTGM----SHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGL 319
            +  + PGT  SQ++ +        S     +    +PGP  P L  +   Q   ++P  
Sbjct: 913 PVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP-- 970

Query: 320 SQPGRSQ 326
             PG S+
Sbjct: 971 -DPGESK 976


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 96/363 (26%), Positives = 135/363 (37%), Gaps = 62/363 (17%)

Query: 5    GMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQ------------PGIRQPDTSQSCKN 52
            GM  PG Q   +S  VP    +S P M    P Q            PG+ +P  S   + 
Sbjct: 1987 GMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQA 2046

Query: 53   QTDMSQPDANQ--SSLSDSNQTGIIQ--PSPSLLGMNQMDMNQWSASLYEMNQVDMKQPS 108
                 +  + Q   S+S S    +++   SPS     Q  +N           +    P 
Sbjct: 2047 AVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLN-----------ILKSNPQ 2095

Query: 109  MSQAGMRQSGTNLPDINQPGMK-QPGTWQLGRSQPGMWPQ-------SLSELVLSEASIS 160
            +  A ++Q  T     NQPGM+ QPG     +SQPGM PQ       SL  L   +A + 
Sbjct: 2096 LMAAFIKQR-TAKYVANQPGMQPQPGL----QSQPGMQPQPGMHQQPSLQNLNAMQAGVP 2150

Query: 161  QPGPPQRAPSQSGPRQSSTS----QAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQ 216
            +PG P +  +  G      +      G N +  S    ++  +R+    Q   +Q    Q
Sbjct: 2151 RPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQ 2210

Query: 217  SGTSQIGMSQPGTWQTGLSQ-PVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTS 275
                Q G +       G  Q   P+ P   PP M Q    Q  M Q +P Q      G  
Sbjct: 2211 QQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQ----QQRMQQHLPLQ--GSSMGQM 2264

Query: 276  QSSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQ----PGRSQPSVSQ 331
             +   Q G      GQPG+     S P + QQ L Q +L Q  + Q    PG+  P   Q
Sbjct: 2265 AAQMGQLGQ----MGQPGL--GADSTPNI-QQALQQRILQQQQMKQQIGSPGQPNPMSPQ 2317

Query: 332  MGM 334
              M
Sbjct: 2318 QHM 2320



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 92/354 (25%), Positives = 131/354 (37%), Gaps = 54/354 (15%)

Query: 18   QQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMS----------QPDANQSSLS 67
            Q +PS P  + PG   Q PS P   QP  +Q   +   MS          QP    S+  
Sbjct: 1880 QSLPS-PTSAPPGTPTQQPSTPQTPQP-PAQPQPSPVSMSPAGFPSVARTQPPTTVSTGK 1937

Query: 68   DSNQTGI----IQPSPSLL-GMNQMDMN-QWSASLYEMNQVDMKQPSMSQAG-----MRQ 116
             ++Q        QP P+ +    Q++   Q    LY +N  +   P  +  G     M  
Sbjct: 1938 PTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAP 1997

Query: 117  SGTNLPDINQ------PGMKQPGTWQ---LGRSQPGMWPQSLSELVLSEASISQPGPPQR 167
               N+P  NQ      P M  PG WQ   L + QP   P     ++  +A  +  GP  R
Sbjct: 1998 VSLNVPRPNQVSGPVMPSM-PPGQWQQAPLPQQQP--MPGLPRPVISMQAQAAVAGP--R 2052

Query: 168  APSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSG--GSQPSMRQVGTSQSGTSQIGMS 225
             PS   PR  S S        +  P   Q   +      S P +      Q  T++   +
Sbjct: 2053 MPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQR-TAKYVAN 2111

Query: 226  QPGTW-QTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGM 284
            QPG   Q GL      QP    PGM Q    QP +      Q G+ +PG     +   G+
Sbjct: 2112 QPGMQPQPGLQSQPGMQPQ---PGMHQ----QPSLQNLNAMQAGVPRPGVPPQQQAMGGL 2164

Query: 285  SHPGRGQPGIWEPG--PSQPGLSQQ---DLNQLVLSQPGLSQPGRSQPSVSQMG 333
            +  G+    I  PG  P+   ++ Q    L + +L Q    Q  + Q    Q G
Sbjct: 2165 NPQGQAL-NIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQG 2217



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 92/367 (25%), Positives = 134/367 (36%), Gaps = 79/367 (21%)

Query: 4    PGMWQPGVQQPGISQQVPSHP---DMSQP--------GMSQQVPSQPG-IRQPDTSQSCK 51
            P +  PG Q P I Q  P  P    +S P        GM+   P   G ++ P      +
Sbjct: 683  PALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPR 742

Query: 52   NQTDMSQPDANQSSLSDSNQTGIIQPS-----PSLLGMNQMDM-------------NQWS 93
              + M+   + Q +   S     I PS     P+++G +  +M             NQ+ 
Sbjct: 743  AASPMNH--SVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFP 800

Query: 94   ASLYEMNQVDMKQPSMSQAGMRQS---GTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLS 150
            +S   M+ V M QP  +Q G+ Q    G  LP  N   M  P   QL        P   +
Sbjct: 801  SSSGAMS-VGMGQPP-AQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLHPT 856

Query: 151  ELVLSEA----SISQPGPPQRAPSQ-SGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGS 205
                S A    S+    PP   P Q + P Q ST  + + Q+    P           GS
Sbjct: 857  PPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTP-----------GS 905

Query: 206  QPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPS 265
             PS  Q  T  + T Q       T       P P+ P + P       +  P  SQQ P+
Sbjct: 906  VPSATQ--TQSTPTVQAAAQAQVT-------PQPQTPVQPP------SVATPQSSQQQPT 950

Query: 266  QLGMRQPGT--SQSSKNQTGM----SHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGL 319
             +  + PGT  SQ++ +        S     +    +PGP  P L  +   Q   ++P  
Sbjct: 951  PVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP-- 1008

Query: 320  SQPGRSQ 326
              PG S+
Sbjct: 1009 -DPGESK 1014


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
            sapiens]
          Length = 2231

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 114/447 (25%), Positives = 160/447 (35%), Gaps = 76/447 (17%)

Query: 2    SPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGI-RQPDTSQSCKNQTDMS--- 57
            S PG   P  Q PG   +  SHP +SQ  M Q+     G  R P  +Q    QT  S   
Sbjct: 687  SIPGSQMPP-QPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP 745

Query: 58   ------QPDANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQ 111
                  Q  A  SS   SN +G   P  S  G             Y         PS S 
Sbjct: 746  HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYG---------PQGNYSRPPAYSGVPSASY 796

Query: 112  A----GMRQSGTNLPDINQPGMKQP-GTWQLGR-----SQPGMWPQSLSELVLSEASISQ 161
            +    GM  S  N   ++  G  QP G   LGR      Q   +P ++S +  S   +SQ
Sbjct: 797  SGPGPGMGISANN--QMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ 854

Query: 162  PGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQ 221
             G P   P    P  +   +A    + + Q        RQ  GS P M Q G   S +  
Sbjct: 855  QGGPGMGP----PMPTVNRKAQEAAAAVMQAAANSAQSRQ--GSFPGMNQSGLMASSSP- 907

Query: 222  IGMSQPGTWQTGLSQP-------VPRQPNKSPPGMWQRGMWQPGMSQ-QVPSQLGMRQPG 273
               SQP    + L           P   N S   +    M  PG S+  +P +   ++ G
Sbjct: 908  --YSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEG 965

Query: 274  TSQ-SSKNQTGMSHPGRGQP----GIWEPGPSQPGLSQQDLNQLVLSQ-PGLSQPGRSQP 327
            T Q  SK++   S  G  QP     +  P P  P  S   ++     +   +S PG  + 
Sbjct: 966  TPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSP--SSASISSFHGDESDSISSPGWPKT 1023

Query: 328  SVSQMGMRQTSMDYFQIRHAEAGDCPE-------ILRLIKELAACENMLDAMELTAADLL 380
              S      T+      +  E G+ PE        L  ++E  +  + L A+     DL 
Sbjct: 1024 PSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLF 1083

Query: 381  RDGFGDNPLFYCL-----IAEVNDQQK 402
            R       L+ C+     +A+VN  +K
Sbjct: 1084 R-------LYVCVKEIGGLAQVNKNKK 1103



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 78/336 (23%), Positives = 118/336 (35%), Gaps = 76/336 (22%)

Query: 1    MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD 60
            M+P   +Q G+  P +  ++P  P+    G  ++V   PG  +P  +Q          P+
Sbjct: 1236 MTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKV---PGSSEPFMTQG-------QMPN 1285

Query: 61   ANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTN 120
            ++   + + + +G +    S LGM Q     + AS    ++                G  
Sbjct: 1286 SSMQDMYNQSPSGAM----SNLGMGQRQQFPYGASYDRRHE--------------PYGQQ 1327

Query: 121  LPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRA-------PSQSG 173
             P    P  + P     G  QPG++PQ  +            GPP +           S 
Sbjct: 1328 YPGQGPPSGQPP----YGGHQPGLYPQQPN---YKRHMDGMYGPPAKRHEGDMYNMQYSS 1380

Query: 174  PRQSSTSQAGTNQSGIS-QPVMWQLDM-----RQSGGSQ------PSMRQVGTSQSGTSQ 221
             +Q   +Q G + SG   +P+  Q        R  G  Q      P     G  QS +S+
Sbjct: 1381 QQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSE 1440

Query: 222  IGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQ---------------QVPSQ 266
                Q   W      P P Q  + P G  Q   + PGM++               Q PS 
Sbjct: 1441 --GPQQNMWAARNDMPYPYQNRQGPGGPTQAPPY-PGMNRTDDMMVPDQRINHESQWPSH 1497

Query: 267  LGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQP 302
            +  RQP  S S+  Q     P   QP    P PS P
Sbjct: 1498 VSQRQPYMSSSASMQPITRPP---QPSYQTP-PSLP 1529


>gi|56117844 synovial sarcoma translocation, chromosome 18 isoform 2
           [Homo sapiens]
          Length = 387

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 85/341 (24%), Positives = 118/341 (34%), Gaps = 73/341 (21%)

Query: 27  SQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSDSNQTGIIQPSPSLLGMNQ 86
           S   M   +P+ P    P       NQ+    P  + +  SD    G   P+P +     
Sbjct: 67  SNQNMQSLLPAPPTQNMP-MGPGGMNQSGPPPPPRSHNMPSDG-MVGGGPPAPHM----- 119

Query: 87  MDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQPGMKQPGTWQLGRSQPGMWP 146
              NQ +  +   N + M+ P  +Q  M  S  N+P  +   M        G     + P
Sbjct: 120 --QNQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSM--------GGYNHSV-P 168

Query: 147 QSLSELVLSEASISQPGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSG--- 203
            S S  V ++ ++SQ  P        GPR + + Q         QP   Q +M Q G   
Sbjct: 169 SSQSMPVQNQMTMSQGQP----MGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQH 224

Query: 204 --GSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMW----------- 250
             G QP M  +G    G   +G  Q          P  R P + PP  +           
Sbjct: 225 YQGQQPPMGMMGQVNQGNHMMGQRQ---------IPPYRPPQQGPPQQYSGQEDYYGDQY 275

Query: 251 -QRGMWQP-GMSQQV----PSQLGMRQ------------PGTSQSSKNQTGMSHPGRGQ- 291
              G   P GM+QQ      SQ G +Q            P   Q    Q G  +PG+ Q 
Sbjct: 276 SHGGQGPPEGMNQQYYPDGNSQYGQQQDAYQGPPPQQGYPPQQQQYPGQQG--YPGQQQG 333

Query: 292 --PGIWEPGPSQPGLSQ---QDLNQLVLSQPGLSQPGRSQP 327
             P    PGP  P   Q   Q       +QPG  QP + +P
Sbjct: 334 YGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRP 374



 Score = 33.1 bits (74), Expect = 0.52
 Identities = 26/102 (25%), Positives = 38/102 (37%)

Query: 231 QTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRG 290
           Q+ L  P  +     P GM Q G   P  S  +PS   +     +   +NQ     PG  
Sbjct: 72  QSLLPAPPTQNMPMGPGGMNQSGPPPPPRSHNMPSDGMVGGGPPAPHMQNQMNGQMPGPN 131

Query: 291 QPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQM 332
              +  PGP+Q  ++   +N    S   +     S PS   M
Sbjct: 132 HMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGYNHSVPSSQSM 173


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 95/365 (26%), Positives = 135/365 (36%), Gaps = 67/365 (18%)

Query: 12  QQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDT-SQSCKNQTDMSQPDANQSSLSDSN 70
           ++  + QQV      SQ G+ Q   +  GI    T S S   Q +  +P+A+Q       
Sbjct: 585 EESSLKQQV-EQSSASQTGIKQLPSASTGIPTASTTSASVSTQVEPEEPEADQHQ----- 638

Query: 71  QTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQ---------------------PSM 109
           Q    QPS S+L    +D  Q S S++  ++V  +Q                     PS 
Sbjct: 639 QLQYQQPSISVLSDGTVDSGQGS-SVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPST 697

Query: 110 SQAGMRQSGTNLPDINQPGMKQ--PGTWQL---GRSQPGMWPQSLSELVLSEASISQPGP 164
            QA  +  G   P     G  Q  P +  L     SQP   PQ        +  I Q  P
Sbjct: 698 VQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQ-------QQGIQQTAP 750

Query: 165 PQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGM 224
           PQ+    S   Q+STS   T    +SQP   Q+  + S G Q  + Q   +  G  QI +
Sbjct: 751 PQQTVQYS-LSQTSTSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPV 809

Query: 225 -SQP-------GTWQTGLSQPVPR------QPNKSPPGMWQRGMWQPGMSQ-QVPSQLGM 269
            +QP       G     + QP+P         ++ P         Q G S   +    G+
Sbjct: 810 ATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQTGFSSLPITMAAGI 869

Query: 270 RQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSV 329
            QP  + +S   T         PG+    PSQ     Q + QL    P    P   QP+V
Sbjct: 870 TQPLLTLASSATTA------AIPGVSTVVPSQLPTLLQPVTQL----PSQVHPQLLQPAV 919

Query: 330 SQMGM 334
             MG+
Sbjct: 920 QSMGI 924


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 86/319 (26%), Positives = 114/319 (35%), Gaps = 50/319 (15%)

Query: 2   SPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGI-RQPDTSQSCKNQTDMS--- 57
           S PG   P  Q PG   +  SHP +SQ  M Q+     G  R P  +Q    QT  S   
Sbjct: 700 SIPGSQMPP-QPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP 758

Query: 58  ------QPDANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQ 111
                 Q  A  SS   SN +G   P  S  G             Y         PS S 
Sbjct: 759 HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYG---------PQGNYSRPPAYSGVPSASY 809

Query: 112 A----GMRQSGTNLPDINQPGMKQP-GTWQLGR-----SQPGMWPQSLSELVLSEASISQ 161
           +    GM  S  N   ++  G  QP G   LGR      Q   +P ++S +  S   +SQ
Sbjct: 810 SGPGPGMGISANN--QMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ 867

Query: 162 PGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQ 221
            G P   P    P  +   +A    + + Q        RQ  GS P M Q G   S +  
Sbjct: 868 QGGPGMGP----PMPTVNRKAQEAAAAVMQAAANSAQSRQ--GSFPGMNQSGLMASSSP- 920

Query: 222 IGMSQPGTWQTGLSQP-------VPRQPNKSPPGMWQRGMWQPGMSQ-QVPSQLGMRQPG 273
              SQP    + L           P   N S   +    M  PG S+  +P +   ++ G
Sbjct: 921 --YSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEG 978

Query: 274 TSQ-SSKNQTGMSHPGRGQ 291
           T Q  SK++   S    G+
Sbjct: 979 TPQPESKSKKSSSSTTTGE 997



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 78/336 (23%), Positives = 118/336 (35%), Gaps = 76/336 (22%)

Query: 1    MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD 60
            M+P   +Q G+  P +  ++P  P+    G  ++V   PG  +P  +Q          P+
Sbjct: 1196 MTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKV---PGSSEPFMTQG-------QMPN 1245

Query: 61   ANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTN 120
            ++   + + + +G +    S LGM Q     + AS    ++                G  
Sbjct: 1246 SSMQDMYNQSPSGAM----SNLGMGQRQQFPYGASYDRRHE--------------PYGQQ 1287

Query: 121  LPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRA-------PSQSG 173
             P    P  + P     G  QPG++PQ  +            GPP +           S 
Sbjct: 1288 YPGQGPPSGQPP----YGGHQPGLYPQQPN---YKRHMDGMYGPPAKRHEGDMYNMQYSS 1340

Query: 174  PRQSSTSQAGTNQSGIS-QPVMWQLDM-----RQSGGSQ------PSMRQVGTSQSGTSQ 221
             +Q   +Q G + SG   +P+  Q        R  G  Q      P     G  QS +S+
Sbjct: 1341 QQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSE 1400

Query: 222  IGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQ---------------QVPSQ 266
                Q   W      P P Q  + P G  Q   + PGM++               Q PS 
Sbjct: 1401 --GPQQNMWAARNDMPYPYQNRQGPGGPTQAPPY-PGMNRTDDMMVPDQRINHESQWPSH 1457

Query: 267  LGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQP 302
            +  RQP  S S+  Q     P   QP    P PS P
Sbjct: 1458 VSQRQPYMSSSASMQPITRPP---QPSYQTP-PSLP 1489


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 86/319 (26%), Positives = 114/319 (35%), Gaps = 50/319 (15%)

Query: 2   SPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGI-RQPDTSQSCKNQTDMS--- 57
           S PG   P  Q PG   +  SHP +SQ  M Q+     G  R P  +Q    QT  S   
Sbjct: 687 SIPGSQMPP-QPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSP 745

Query: 58  ------QPDANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQ 111
                 Q  A  SS   SN +G   P  S  G             Y         PS S 
Sbjct: 746 HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYG---------PQGNYSRPPAYSGVPSASY 796

Query: 112 A----GMRQSGTNLPDINQPGMKQP-GTWQLGR-----SQPGMWPQSLSELVLSEASISQ 161
           +    GM  S  N   ++  G  QP G   LGR      Q   +P ++S +  S   +SQ
Sbjct: 797 SGPGPGMGISANN--QMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQ 854

Query: 162 PGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQ 221
            G P   P    P  +   +A    + + Q        RQ  GS P M Q G   S +  
Sbjct: 855 QGGPGMGP----PMPTVNRKAQEAAAAVMQAAANSAQSRQ--GSFPGMNQSGLMASSSP- 907

Query: 222 IGMSQPGTWQTGLSQP-------VPRQPNKSPPGMWQRGMWQPGMSQ-QVPSQLGMRQPG 273
              SQP    + L           P   N S   +    M  PG S+  +P +   ++ G
Sbjct: 908 --YSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEG 965

Query: 274 TSQ-SSKNQTGMSHPGRGQ 291
           T Q  SK++   S    G+
Sbjct: 966 TPQPESKSKKSSSSTTTGE 984



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 78/336 (23%), Positives = 118/336 (35%), Gaps = 76/336 (22%)

Query: 1    MSPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPD 60
            M+P   +Q G+  P +  ++P  P+    G  ++V   PG  +P  +Q          P+
Sbjct: 1183 MTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKV---PGSSEPFMTQG-------QMPN 1232

Query: 61   ANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTN 120
            ++   + + + +G +    S LGM Q     + AS    ++                G  
Sbjct: 1233 SSMQDMYNQSPSGAM----SNLGMGQRQQFPYGASYDRRHE--------------PYGQQ 1274

Query: 121  LPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRA-------PSQSG 173
             P    P  + P     G  QPG++PQ  +            GPP +           S 
Sbjct: 1275 YPGQGPPSGQPP----YGGHQPGLYPQQPN---YKRHMDGMYGPPAKRHEGDMYNMQYSS 1327

Query: 174  PRQSSTSQAGTNQSGIS-QPVMWQLDM-----RQSGGSQ------PSMRQVGTSQSGTSQ 221
             +Q   +Q G + SG   +P+  Q        R  G  Q      P     G  QS +S+
Sbjct: 1328 QQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSE 1387

Query: 222  IGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQ---------------QVPSQ 266
                Q   W      P P Q  + P G  Q   + PGM++               Q PS 
Sbjct: 1388 --GPQQNMWAARNDMPYPYQNRQGPGGPTQAPPY-PGMNRTDDMMVPDQRINHESQWPSH 1444

Query: 267  LGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQP 302
            +  RQP  S S+  Q     P   QP    P PS P
Sbjct: 1445 VSQRQPYMSSSASMQPITRPP---QPSYQTP-PSLP 1476


>gi|56117846 synovial sarcoma translocation, chromosome 18 isoform 1
           [Homo sapiens]
          Length = 418

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 85/353 (24%), Positives = 114/353 (32%), Gaps = 77/353 (21%)

Query: 1   MSPPGMWQPGVQQPGISQQV------PSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKN-- 52
           M   GM   G   P +  Q+      P+H  M  PG +Q   +   +  P +S       
Sbjct: 104 MPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSMGGY 163

Query: 53  ----QTDMSQPDANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPS 108
                +  S P  NQ ++S     G   P P++     M  NQ          +  +QP 
Sbjct: 164 NHSVPSSQSMPVQNQMTMSQGQPMGNYGPRPNM----SMQPNQ--------GPMMHQQPP 211

Query: 109 MSQAGMRQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRA 168
             Q  M Q G       QP M   G    G    G                 +  PP R 
Sbjct: 212 SQQYNMPQGGGQHYQGQQPPMGMMGQVNQGNHMMG----------------QRQIPPYRP 255

Query: 169 PSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQ----SGTSQIGM 224
           P Q  P+Q S  +             +  D    GG  P     G +Q     G +  G 
Sbjct: 256 PQQGPPQQYSGQED------------YYGDQYSHGGQGP---PEGMNQQYYPDGHNDYGY 300

Query: 225 SQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQV----PSQLGMRQPGTSQSSKN 280
            QP   + G  +P       S    ++ G  Q G  Q      P Q G   P   Q    
Sbjct: 301 QQPSYPEQGYDRPY----EDSSQHYYEGGNSQYGQQQDAYQGPPPQQG--YPPQQQQYPG 354

Query: 281 QTGMSHPGRGQ---PGIWEPGPSQPGLSQ---QDLNQLVLSQPGLSQPGRSQP 327
           Q G  +PG+ Q   P    PGP  P   Q   Q       +QPG  QP + +P
Sbjct: 355 QQG--YPGQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQPPQQRP 405



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 82/326 (25%), Positives = 112/326 (34%), Gaps = 54/326 (16%)

Query: 27  SQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSDSNQTGIIQPSPSLLGMNQ 86
           S   M   +P+ P    P       NQ+    P  + +  SD    G   P+P +     
Sbjct: 67  SNQNMQSLLPAPPTQNMP-MGPGGMNQSGPPPPPRSHNMPSDG-MVGGGPPAPHM----- 119

Query: 87  MDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQPGMKQPGTWQLGRSQPGMWP 146
              NQ +  +   N + M+ P  +Q  M  S  N+P  +   M        G     + P
Sbjct: 120 --QNQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSM--------GGYNHSV-P 168

Query: 147 QSLSELVLSEASISQPGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSG--- 203
            S S  V ++ ++SQ  P        GPR + + Q         QP   Q +M Q G   
Sbjct: 169 SSQSMPVQNQMTMSQGQP----MGNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQGGGQH 224

Query: 204 --GSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMW----------- 250
             G QP M  +G    G   +G  Q          P  R P + PP  +           
Sbjct: 225 YQGQQPPMGMMGQVNQGNHMMGQRQ---------IPPYRPPQQGPPQQYSGQEDYYGDQY 275

Query: 251 -QRGMWQP-GMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGR-GQPGIWEPGPSQPGLSQQ 307
              G   P GM+QQ     G    G  Q S  + G   P        +E G SQ G  QQ
Sbjct: 276 SHGGQGPPEGMNQQYYPD-GHNDYGYQQPSYPEQGYDRPYEDSSQHYYEGGNSQYG-QQQ 333

Query: 308 DLNQLVLSQPGLSQPGRSQPSVSQMG 333
           D  Q    Q G   P + Q    Q G
Sbjct: 334 DAYQGPPPQQG--YPPQQQQYPGQQG 357


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 83/322 (25%), Positives = 124/322 (38%), Gaps = 46/322 (14%)

Query: 38  QPGIRQPDTSQSCKNQTDMSQPDANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLY 97
           +P +  P  S S  + TD       +  L D      +  S  L   N  D+NQ   SL 
Sbjct: 15  RPKLSSPALSASASDGTDFGSLFDLEHDLPDE-----LINSTELGLTNGGDINQLQTSLG 69

Query: 98  EMNQVDMKQPSMSQAGMRQSGTNLPDINQPGMKQPG---TWQLGRSQPGMWPQSLSELVL 154
            +     K   +S+  + +SG++ P++N  G+  PG     Q  +S PG+    ++ +V 
Sbjct: 70  MVQDAASKHKQLSE--LLRSGSS-PNLNM-GVGGPGQVMASQAQQSSPGLG--LINSMVK 123

Query: 155 SEASISQPGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGT 214
           S  + +    P      SGP Q  T   G   S ++QP M  ++   + G  P M   G 
Sbjct: 124 SPMTQAGLTSPNMGMGTSGPNQGPTQSTGMMNSPVNQPAM-GMNTGMNAGMNPGMLAAGN 182

Query: 215 SQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRG--MWQPGM--SQQVPSQLGMR 270
            Q       M+  G+   G  +   + PN   PGM   G  + +P    S Q+  Q G+R
Sbjct: 183 GQGIMPNQVMN--GSIGAGRGRQNMQYPN---PGMGSAGNLLTEPLQQGSPQMGGQTGLR 237

Query: 271 QPGTSQSSKNQTGMSHPG-RGQPGIWEPGP--SQPGLSQQDLNQLVLSQ----------- 316
            P   +       M++P   G P    PG      GL  Q   + VLS            
Sbjct: 238 GPQPLKMGM----MNNPNPYGSPYTQNPGQQIGASGLGLQIQTKTVLSNNLSPFAMDKKA 293

Query: 317 -PGLSQPGRSQ---PSVSQMGM 334
            PG   P   Q   P V Q G+
Sbjct: 294 VPGGGMPNMGQQPAPQVQQPGL 315



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 90/371 (24%), Positives = 140/371 (37%), Gaps = 54/371 (14%)

Query: 3    PPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDAN 62
            P G  +PG+   G+ QQ    P  SQ G+ Q    Q G+ +P    +  +     QP  N
Sbjct: 1976 PSGHLEPGMGPTGMQQQ----PPWSQGGLPQPQQLQSGMPRP----AMMSVAQHGQP-LN 2026

Query: 63   QSSLSDSNQTGIIQPSPSLLGMNQMD-----MNQWSASLYEMNQVDM--KQPSMSQAGMR 115
             +      Q GI    P  +    +      +   S+ L +   + +    P +  A ++
Sbjct: 2027 MAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIK 2086

Query: 116  QSGTNLPDIN-QPGMKQPGTWQLGRSQPGMWPQSL--SELVLSEASISQPGPPQRAPSQS 172
            Q      + N QP   QPG   + + QPG+ P ++   + V S  ++    P Q    ++
Sbjct: 2087 QRAAKYANSNPQPIPGQPG---MPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQRA 2143

Query: 173  G-PRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPS----------MRQVGTSQSGTSQ 221
            G P+Q    Q      G+S P   Q++M  +  + PS          M Q    Q     
Sbjct: 2144 GLPQQQPQQQLQPPMGGMS-PQAQQMNMNHN--TMPSQFRDILRRQQMMQQQQQQGAGPG 2200

Query: 222  I--GMSQPGTWQ--TGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQS 277
            I  GM+    +Q   G+  P P+Q  +    M Q      G   Q+P  LG     + Q+
Sbjct: 2201 IGPGMANHNQFQQPQGVGYP-PQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQA 2259

Query: 278  SKNQTGMSHPGRG-QPGIWEPG----PSQ---PGLSQQDL-----NQLVLSQPGLSQPGR 324
             + +      G   QP    P     P+Q   P L  Q +     NQ+   QP  S   +
Sbjct: 2260 YQQRLLQQQMGSPVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQ 2319

Query: 325  SQPSVSQMGMR 335
            SQP  S    R
Sbjct: 2320 SQPPHSSPSPR 2330



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 71/278 (25%), Positives = 100/278 (35%), Gaps = 31/278 (11%)

Query: 77   PSPSLLGMNQ-MDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQ-----PGMK 130
            P P  L + Q +   Q    L +   +  +  SM + G+      LP         P  +
Sbjct: 1802 PVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQ 1861

Query: 131  QPGTWQLGR--SQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTSQAGTNQSG 188
            QP T Q  +  SQP   P +     L     + P    +A  Q  P     +   T Q  
Sbjct: 1862 QPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTP----PTPPQTAQPP 1917

Query: 189  ISQPVMWQLDMR-QSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPP 247
            +  P    ++M  Q   +  + RQ+   Q     I    P           P    + P 
Sbjct: 1918 LPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPS 1977

Query: 248  GMWQRGMWQPGMSQQVP-SQLGMRQPGTSQSSKNQTGM-------------SHPGRGQPG 293
            G  + GM   GM QQ P SQ G+ QP   QS   +  M               PG GQ G
Sbjct: 1978 GHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVG 2037

Query: 294  IWEPGPSQPG-LSQQDLNQLVLSQPGLSQPGRSQPSVS 330
            I    P +PG +SQQ L  L+ +    S P + Q  +S
Sbjct: 2038 I---SPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLS 2072



 Score = 35.8 bits (81), Expect = 0.081
 Identities = 61/281 (21%), Positives = 99/281 (35%), Gaps = 27/281 (9%)

Query: 18   QQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSDSNQTGIIQP 77
            Q +P  P M Q     Q P+ PG +   ++ + +N   M Q    ++ L        +QP
Sbjct: 2098 QPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPM-QAGVQRAGLPQQQPQQQLQP 2156

Query: 78   SPSLLG--MNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQPGMKQPGTW 135
                +     QM+MN  +    +   +  +Q  M Q   + +G  +     PGM     +
Sbjct: 2157 PMGGMSPQAQQMNMNH-NTMPSQFRDILRRQQMMQQQQQQGAGPGI----GPGMANHNQF 2211

Query: 136  Q--LGRSQPGMWPQSLSELV--LSEASISQPGP-PQRAPSQSGPRQSSTSQAGTNQSGIS 190
            Q   G   P    Q +   +  + + ++ Q G  PQ   +++G    +  Q    Q   S
Sbjct: 2212 QQPQGVGYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQQQMGS 2271

Query: 191  ----QPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSP 246
                 P+  Q  M  +    P ++      S ++Q+   QP         P PR P   P
Sbjct: 2272 PVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQP--------VPSPR-PQSQP 2322

Query: 247  PGMWQRGMWQPGMS-QQVPSQLGMRQPGTSQSSKNQTGMSH 286
            P        QP  S   V  Q     PG   +  N     H
Sbjct: 2323 PHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGH 2363



 Score = 33.5 bits (75), Expect = 0.40
 Identities = 33/113 (29%), Positives = 45/113 (39%), Gaps = 10/113 (8%)

Query: 2   SPPGMWQPGVQQPGIS---QQVPSHPDMSQPGMSQ-QVPSQPGIRQPDTSQSCKNQTDMS 57
           +PP M  PG Q   +    +Q P+ P    P   Q  +P+ P   QP      +  T  S
Sbjct: 865 TPPAM-PPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAAS 923

Query: 58  QPDANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQ--VDMKQPS 108
            P      L     T + QP+ S+ G      N  S S  E+N   +  KQPS
Sbjct: 924 VPTPTAPLLPPQPATPLSQPAVSIEGQVS---NPPSTSSTEVNSQAIAEKQPS 973



 Score = 29.3 bits (64), Expect = 7.5
 Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 11/59 (18%)

Query: 283  GMSHPG--RGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQTSM 339
            GM+ P   RG  G  EPG    G+ QQ         P  SQ G  QP   Q GM + +M
Sbjct: 1966 GMNPPPMTRGPSGHLEPGMGPTGMQQQ---------PPWSQGGLPQPQQLQSGMPRPAM 2015


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 61/208 (29%), Positives = 82/208 (39%), Gaps = 26/208 (12%)

Query: 116  QSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSEL-------VLSEASISQPGPPQRA 168
            QS +  P   QP   QP      + QP   PQS ++        V ++ ++S   P +  
Sbjct: 2259 QSSSVGPAEAQPQTAQPSA----QPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQ 2314

Query: 169  PSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPG 228
            P+ +   QSS  Q    QS     V  Q  +R    SQ  +R      S  SQ+   Q  
Sbjct: 2315 PTHA---QSSKPQVAA-QSQPQSNVQGQSPVRVQSPSQTRIRP-----STPSQLSPGQQS 2365

Query: 229  TWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPG 288
              QT  SQP+P QP+ S     Q      G  Q  P      Q  +S  + NQ  +S P 
Sbjct: 2366 QVQTTTSQPIPIQPHTSLQIPSQ------GQPQSQPQVQSSTQTLSSGQTLNQVTVSSPS 2419

Query: 289  RGQPGIWEPGPSQPGLSQQDLNQLVLSQ 316
            R Q  I +P P    + Q      VLSQ
Sbjct: 2420 RPQLQIQQPQPQVIAVPQLQQQVQVLSQ 2447



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 87/341 (25%), Positives = 130/341 (38%), Gaps = 42/341 (12%)

Query: 4    PGMW--QPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDA 61
            PGM   +  +QQ  + + +   P M QPG  QQV +Q    QP ++      T  S P  
Sbjct: 2059 PGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTP-- 2116

Query: 62   NQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNL 121
             Q SL+ +  T  IQ S S                 +  QV +    ++Q      G   
Sbjct: 2117 GQKSLTSATSTSNIQSSAS------------QPPRPQQGQVKLTMAQLTQLTQGHGGNQG 2164

Query: 122  PDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQ--SGPRQSST 179
              +   G  Q         Q  + PQ ++ L      + Q   P     +    P  ++ 
Sbjct: 2165 LTVVIQGQGQT------TGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTA 2218

Query: 180  SQAGTNQSGISQPVMWQLDMRQSGGSQPSM-----RQVGTSQSGTSQIGMSQPGTWQTGL 234
            + A T  + +S       + RQS  S P M     + +  +QS +     +QP T Q   
Sbjct: 2219 TTASTTTTTVSTTAAGTGEQRQSKLS-PQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPS- 2276

Query: 235  SQPVPRQPNKSP--PGMWQRG--MWQPGMSQQVPSQLGMRQPGTSQSSKNQ-TGMSHPG- 288
            +QP P+   +SP  P +  +     Q  +S  VPS+    QP  +QSSK Q    S P  
Sbjct: 2277 AQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSE---AQPTHAQSSKPQVAAQSQPQS 2333

Query: 289  --RGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQP 327
              +GQ  +    PSQ  +     +QL   Q    Q   SQP
Sbjct: 2334 NVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQP 2374



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 24/214 (11%)

Query: 4    PGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQ--PDA 61
            P   QP   QP    Q  + P         Q P+QP ++   T    + QT +S   P  
Sbjct: 2265 PAEAQPQTAQPSAQPQPQTQP---------QSPAQPEVQ---TQPEVQTQTTVSSHVPSE 2312

Query: 62   NQSSLSDSNQTGI-IQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTN 120
             Q + + S++  +  Q  P      Q  +   S S   +      Q S  Q    Q+ T+
Sbjct: 2313 AQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTS 2372

Query: 121  LPDINQP--GMKQPGTWQLGRSQPGMW--PQSLSE-LVLSEASISQPGPPQRAPSQSGPR 175
             P   QP   ++ P   Q  +SQP +    Q+LS    L++ ++S P  PQ    Q  P+
Sbjct: 2373 QPIPIQPHTSLQIPSQGQ-PQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQ 2431

Query: 176  QSSTSQAGTNQSGISQ---PVMWQLDMRQSGGSQ 206
              +  Q       +SQ    V+ Q+  +QSG  Q
Sbjct: 2432 VIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQ 2465


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 92/392 (23%), Positives = 134/392 (34%), Gaps = 55/392 (14%)

Query: 12  QQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQS---SLSD 68
           QQ    QQ  +     Q    QQ  +Q    Q       + Q  + Q    Q     L  
Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHH 225

Query: 69  SNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQPG 128
            NQ  I Q    L  + Q+ + Q      +  Q   +Q    QA   Q     P I QP 
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQ------QQQQQQQQQQQQQQALQAQ-----PPIQQPP 274

Query: 129 MKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQ----------SS 178
           M+QP   Q   SQ    PQ L ++  ++     P P Q   +Q+ P Q           S
Sbjct: 275 MQQP---QPPPSQ--ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS 329

Query: 179 TSQAGTNQSGISQPVMWQLD---MRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLS 235
            +QA   Q   +QP +  +    + Q    QP ++Q  T+        M  PG   +  S
Sbjct: 330 QAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSS 389

Query: 236 QPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIW 295
            P+   P  SP    Q     P   Q  P      QPG   S  N    S P        
Sbjct: 390 LPMLSSP--SPGQQVQTPQSMPPPPQPSP------QPGQPSSQPNSNVSSGPAPSPSSFL 441

Query: 296 ---EPGPSQPGLSQQDLNQLVLSQPG-LSQPGRSQPSVSQMGMRQTSMDYFQIRHAEAGD 351
               P PSQ  ++ +      +  PG L+ P      +S  G  Q     +  +  +   
Sbjct: 442 PSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSK 501

Query: 352 CPEILRLI-----------KELAACENMLDAM 372
             E LR +           K+L+  +++LD +
Sbjct: 502 YIEPLRRMINKIDKNEDRKKDLSKMKSLLDIL 533



 Score = 32.3 bits (72), Expect = 0.89
 Identities = 50/225 (22%), Positives = 78/225 (34%), Gaps = 18/225 (8%)

Query: 107 PSMSQAGMRQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQ 166
           P  S  GM   G     ++  G   PGT        GM P S++  V+S A+       Q
Sbjct: 106 PGQSLGGMGSLGAMGQPMSLSGQPPPGT-------SGMAPHSMA--VVSTATPQTQLQLQ 156

Query: 167 RAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQ 226
           +   Q   +Q    Q         Q    Q   +Q    Q   +Q    Q   + +   Q
Sbjct: 157 QVALQQQQQQQQFQQ--------QQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQ 208

Query: 227 PGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSH 286
               Q    Q + +  +++   + Q+   Q     Q+  Q   +Q    Q  + Q   + 
Sbjct: 209 QLQQQQQQQQHLIKLHHQNQQQIQQQQQ-QLQRIAQLQLQQQQQQQQQQQQQQQQALQAQ 267

Query: 287 PGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQ 331
           P   QP + +P P       Q L Q+  +Q     P   QP V+Q
Sbjct: 268 PPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ 312



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 6/79 (7%)

Query: 8   QPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQP------DA 61
           QP VQQ   + Q      M  PG+     S P +  P   Q  +    M  P        
Sbjct: 360 QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG 419

Query: 62  NQSSLSDSNQTGIIQPSPS 80
             SS  +SN +    PSPS
Sbjct: 420 QPSSQPNSNVSSGPAPSPS 438


>gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]
          Length = 1446

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 44/151 (29%), Positives = 58/151 (38%), Gaps = 16/151 (10%)

Query: 146 PQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGS 205
           P +   L + + S SQ  P Q +PSQ   RQ STSQA  +Q   SQ    Q++  Q   S
Sbjct: 635 PSTAPGLGMDQGSPSQVNPSQGSPSQGSLRQESTSQASPSQRSTSQGSPSQVNPSQRSTS 694

Query: 206 QPSMRQVGTSQSGTSQIGMSQPGTWQ-------------TGLSQPVPRQPNKSPPGMWQR 252
             +  Q   SQ   SQ   SQ  T Q             T  S       +  PPG    
Sbjct: 695 HANSSQGSPSQGSPSQESPSQGSTSQASPSHRNTIGVIGTTSSPKATGSTHSFPPGATDG 754

Query: 253 GMWQPGMSQQVPSQLGMRQPGTSQSSKNQTG 283
            +  PG   Q+     M  P     +++ TG
Sbjct: 755 PLALPG---QLQGNSIMEPPSWPSPTEDPTG 782



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 53/188 (28%), Positives = 74/188 (39%), Gaps = 34/188 (18%)

Query: 68  DSNQTG--IIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDIN 125
           D N TG  + Q  PS      + M+Q S S     QV+  Q S SQ  +RQ  T+    +
Sbjct: 622 DRNNTGKGVEQEVPSTAP--GLGMDQGSPS-----QVNPSQGSPSQGSLRQESTSQASPS 674

Query: 126 QPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTSQAGTN 185
           Q    Q    Q+  SQ             S A+ SQ  P Q +PSQ  P Q STSQA  +
Sbjct: 675 QRSTSQGSPSQVNPSQRST----------SHANSSQGSPSQGSPSQESPSQGSTSQASPS 724

Query: 186 QSGISQPVMWQLDMRQSGGSQPSMRQVGTSQS---GTSQIGMSQPGTWQTG--LSQPVPR 240
                  +          G+  S +  G++ S   G +   ++ PG  Q    +  P   
Sbjct: 725 HRNTIGVI----------GTTSSPKATGSTHSFPPGATDGPLALPGQLQGNSIMEPPSWP 774

Query: 241 QPNKSPPG 248
            P + P G
Sbjct: 775 SPTEDPTG 782



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 42/138 (30%), Positives = 57/138 (41%), Gaps = 18/138 (13%)

Query: 201 QSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMS 260
           Q+   +PS R+      G++ +G  +  T + G+ Q VP     + PG+        GM 
Sbjct: 603 QAWTPEPSPRR-----GGSNVVGYDRNNTGK-GVEQEVP----STAPGL--------GMD 644

Query: 261 QQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLS 320
           Q  PSQ+   Q   SQ S  Q   S     Q    +  PSQ   SQ+  +    SQ   S
Sbjct: 645 QGSPSQVNPSQGSPSQGSLRQESTSQASPSQRSTSQGSPSQVNPSQRSTSHANSSQGSPS 704

Query: 321 QPGRSQPSVSQMGMRQTS 338
           Q   SQ S SQ    Q S
Sbjct: 705 QGSPSQESPSQGSTSQAS 722



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 30/152 (19%)

Query: 162 PGPPQRAPS-------QSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGT 214
           PG PQ  P+       +  PR+  ++  G +++   + V  ++     G        +G 
Sbjct: 592 PGYPQGTPAAGQAWTPEPSPRRGGSNVVGYDRNNTGKGVEQEVPSTAPG--------LGM 643

Query: 215 SQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGT 274
            Q   SQ+  SQ    Q  L Q    Q + S          Q   SQ  PSQ+   Q  T
Sbjct: 644 DQGSPSQVNPSQGSPSQGSLRQESTSQASPS----------QRSTSQGSPSQVNPSQRST 693

Query: 275 SQSSKNQTGMSHPGRGQPGIWEPGPSQPGLSQ 306
           S ++ +Q     P +G P   +  PSQ   SQ
Sbjct: 694 SHANSSQ---GSPSQGSPS--QESPSQGSTSQ 720



 Score = 34.7 bits (78), Expect = 0.18
 Identities = 41/144 (28%), Positives = 55/144 (38%), Gaps = 13/144 (9%)

Query: 5   GMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQS 64
           GM Q    Q   SQ  PS   + Q   SQ  PSQ    Q   SQ   +Q   S  +++Q 
Sbjct: 642 GMDQGSPSQVNPSQGSPSQGSLRQESTSQASPSQRSTSQGSPSQVNPSQRSTSHANSSQG 701

Query: 65  SLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDI 124
           S S        Q SPS    +Q   +Q S S    N + +   + S      + +  P  
Sbjct: 702 SPS--------QGSPSQESPSQGSTSQASPS--HRNTIGVIGTTSSPKATGSTHSFPPGA 751

Query: 125 NQPGMKQPGTWQLGRS--QPGMWP 146
               +  PG  Q G S  +P  WP
Sbjct: 752 TDGPLALPGQLQ-GNSIMEPPSWP 774


>gi|219802034 nuclear factor related to kappaB binding protein
           isoform 1 [Homo sapiens]
          Length = 1299

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 23/185 (12%)

Query: 164 PPQRAPSQSGPRQSSTSQAGTNQSGI---SQPVMWQLDMRQSGGSQPSMRQVGTSQSGTS 220
           PP  A ++SGP  S+ S+   + SG+   S P M  L    S    P+  Q   S    +
Sbjct: 738 PPVSAVNKSGP--STVSEPAKSSSGVLLVSSPTMPHLGTMLS----PASSQTAPSSQAAA 791

Query: 221 QIGMSQPGTWQTGLSQP-VPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSK 279
           ++ +S  G+   GLSQ  V  QP  S P + Q+         Q+P+   +R P T+  +K
Sbjct: 792 RV-VSHSGS--AGLSQVRVVAQP--SLPAVPQQSGGPAQTLPQMPAGPQIRVPATATQTK 846

Query: 280 --NQTGMSH-PGRGQPG---IWEPGPSQPGLSQQDLNQLV--LSQPGLSQPGRSQPSVSQ 331
              QT M+  P + Q     +  PGP Q GL+   L      +S+P  S PG S PS S 
Sbjct: 847 VVPQTVMATVPVKAQTTAATVQRPGPGQTGLTVTSLPATASPVSKPATSSPGTSAPSAST 906

Query: 332 MGMRQ 336
             + Q
Sbjct: 907 AAVIQ 911


>gi|23346420 nuclear factor related to kappaB binding protein
           isoform 2 [Homo sapiens]
          Length = 1324

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 58/185 (31%), Positives = 84/185 (45%), Gaps = 23/185 (12%)

Query: 164 PPQRAPSQSGPRQSSTSQAGTNQSGI---SQPVMWQLDMRQSGGSQPSMRQVGTSQSGTS 220
           PP  A ++SGP  S+ S+   + SG+   S P M  L    S    P+  Q   S    +
Sbjct: 763 PPVSAVNKSGP--STVSEPAKSSSGVLLVSSPTMPHLGTMLS----PASSQTAPSSQAAA 816

Query: 221 QIGMSQPGTWQTGLSQP-VPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSK 279
           ++ +S  G+   GLSQ  V  QP  S P + Q+         Q+P+   +R P T+  +K
Sbjct: 817 RV-VSHSGS--AGLSQVRVVAQP--SLPAVPQQSGGPAQTLPQMPAGPQIRVPATATQTK 871

Query: 280 --NQTGMSH-PGRGQPG---IWEPGPSQPGLSQQDLNQLV--LSQPGLSQPGRSQPSVSQ 331
              QT M+  P + Q     +  PGP Q GL+   L      +S+P  S PG S PS S 
Sbjct: 872 VVPQTVMATVPVKAQTTAATVQRPGPGQTGLTVTSLPATASPVSKPATSSPGTSAPSAST 931

Query: 332 MGMRQ 336
             + Q
Sbjct: 932 AAVIQ 936


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 89/350 (25%), Positives = 105/350 (30%), Gaps = 56/350 (16%)

Query: 2   SPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDA 61
           SPPG  Q    Q G   Q P  P    PG  Q  P Q G +        K Q    Q D 
Sbjct: 52  SPPGKPQGPPPQGGNQPQGPPPP----PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK 107

Query: 62  NQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNL 121
           ++S  S   +       P   G NQ              Q     P   Q    Q G   
Sbjct: 108 SRSPRSPPGKP----QGPPPQGGNQP-------------QGPPPPPGKPQGPPPQGGNKP 150

Query: 122 PDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPR------ 175
                PG  Q           G  PQ  ++   S +S S PG PQ  P Q G +      
Sbjct: 151 QGPPPPGKPQ-----------GPPPQGDNK---SRSSRSPPGKPQGPPPQGGNQPQGPPP 196

Query: 176 -----QSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTW 230
                Q    Q G    G   P   Q    Q      S R       G    G +QP   
Sbjct: 197 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQG- 255

Query: 231 QTGLSQPVPRQPNKSPP--GMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPG 288
                 P P +P   PP  G   +G   PG  Q  P Q G +   +        G    G
Sbjct: 256 ----PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQG 311

Query: 289 RGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMRQTS 338
             QP   +  P  PG  Q    Q      G   PG+ Q    Q G +  S
Sbjct: 312 GNQP---QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 358



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 85/319 (26%), Positives = 98/319 (30%), Gaps = 58/319 (18%)

Query: 2   SPPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDA 61
           SPPG  Q    Q G   Q P  P    PG  Q  P Q G +        K Q    Q D 
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPP----PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD- 167

Query: 62  NQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNL 121
           N+S  S S       P P   G NQ              Q     P   Q    Q G   
Sbjct: 168 NKSRSSRSPPGKPQGPPPQ--GGNQP-------------QGPPPPPGKPQGPPPQGGNKP 212

Query: 122 PDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQSGPR------ 175
                PG  Q           G  PQ  ++   S+++ S PG PQ  P Q G +      
Sbjct: 213 QGPPPPGKPQ-----------GPPPQGDNK---SQSARSPPGKPQGPPPQGGNQPQGPPP 258

Query: 176 -----QSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTW 230
                Q    Q G    G   P   Q    Q G    S R       G    G +QP   
Sbjct: 259 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG- 317

Query: 231 QTGLSQPVPRQPNKSPP--GMWQRGMWQPGMSQQVPSQLGMRQ------PGTSQSSKNQT 282
                 P P +P   PP  G   +G   PG  Q  P Q G +       PG  Q    Q 
Sbjct: 318 ----PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQE 373

Query: 283 GMSHPGRGQPGIWEPGPSQ 301
           G +  G   P    P   Q
Sbjct: 374 GNNPQGPPPPAGGNPQQPQ 392


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 71/249 (28%), Positives = 94/249 (37%), Gaps = 42/249 (16%)

Query: 86  QMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQ-------PGMKQPGTWQLG 138
           ++ +N+ + +L    Q D   P     G   S   LP   Q       P  +Q    Q G
Sbjct: 408 ELVVNKMAQALPRQRQRDAS-PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGG 466

Query: 139 RSQPGMWPQSLSELVLS------EASISQPGPP------QRAPSQSGPRQSSTSQAGTNQ 186
             QPG  PQ     +        +  +S  GPP      QR PS +   Q   SQA    
Sbjct: 467 PPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPT 526

Query: 187 SGI---SQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPN 243
            G    S+PV         G   P   +   S S   Q G  Q  T QT +S P P + +
Sbjct: 527 QGQGRQSRPVA-------GGPGAPPAARPPASPSPQRQAGPPQ-ATRQTSVSGPAPPKAS 578

Query: 244 KSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPG 303
            +PPG    G  + G  Q+ P   G     T Q+S  Q G   P  G P   +P PS PG
Sbjct: 579 GAPPG----GQQRQGPPQKPPGPAG----PTRQAS--QAG-PVPRTGPPTTQQPRPSGPG 627

Query: 304 LSQQDLNQL 312
            + +   QL
Sbjct: 628 PAGRPKPQL 636



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 67/289 (23%), Positives = 98/289 (33%), Gaps = 44/289 (15%)

Query: 52  NQTDMSQPDANQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQ 111
           N+   + P   Q   S    +    PSP  L + +    Q +    +        P    
Sbjct: 412 NKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG 471

Query: 112 AGMRQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQ 171
            G ++ G  L     P   Q     LG       PQ L       ++  QP      P+Q
Sbjct: 472 PGPQRQGPPLQQ-RPPPQGQQHLSGLGPPAGSPLPQRLPS---PTSAPQQPASQAAPPTQ 527

Query: 172 SGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPG--- 228
              RQS     G      ++P       RQ+G  Q + RQ   S     +   + PG   
Sbjct: 528 GQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQAT-RQTSVSGPAPPKASGAPPGGQQ 586

Query: 229 --------------TWQTGLSQPVPR-------QPNKSPPGMWQRGMWQPGMSQQVPSQL 267
                         T Q   + PVPR       QP  S PG    G  +P ++Q+ PSQ 
Sbjct: 587 RQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPG--PAGRPKPQLAQK-PSQ- 642

Query: 268 GMRQPGTSQSSKNQTGMSHPGRGQP-------GIWEPGPSQPGLSQQDL 309
            +  P T+ +     G  HP   +         + EP P +P LSQ ++
Sbjct: 643 DVPPPATAAAG----GPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEV 687


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 71/249 (28%), Positives = 94/249 (37%), Gaps = 42/249 (16%)

Query: 86  QMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPDINQ-------PGMKQPGTWQLG 138
           ++ +N+ + +L    Q D   P     G   S   LP   Q       P  +Q    Q G
Sbjct: 408 ELVVNKMAQALPRQRQRDAS-PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGG 466

Query: 139 RSQPGMWPQSLSELVLS------EASISQPGPP------QRAPSQSGPRQSSTSQAGTNQ 186
             QPG  PQ     +        +  +S  GPP      QR PS +   Q   SQA    
Sbjct: 467 PPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPT 526

Query: 187 SGI---SQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPGTWQTGLSQPVPRQPN 243
            G    S+PV         G   P   +   S S   Q G  Q  T QT +S P P + +
Sbjct: 527 QGQGRQSRPVA-------GGPGAPPAARPPASPSPQRQAGPPQ-ATRQTSVSGPAPPKAS 578

Query: 244 KSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPG 303
            +PPG    G  + G  Q+ P   G     T Q+S  Q G   P  G P   +P PS PG
Sbjct: 579 GAPPG----GQQRQGPPQKPPGPAG----PTRQAS--QAG-PVPRTGPPTTQQPRPSGPG 627

Query: 304 LSQQDLNQL 312
            + +   QL
Sbjct: 628 PAGRPKPQL 636


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 87/341 (25%), Positives = 130/341 (38%), Gaps = 42/341 (12%)

Query: 4    PGMW--QPGVQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDA 61
            PGM   +  +QQ  + + +   P M QPG  QQV +Q    QP ++      T  S P  
Sbjct: 2185 PGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTP-- 2242

Query: 62   NQSSLSDSNQTGIIQPSPSLLGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNL 121
             Q SL+ +  T  IQ S S                 +  QV +    ++Q      G   
Sbjct: 2243 GQKSLTSATSTSNIQSSAS------------QPPRPQQGQVKLTMAQLTQLTQGHGGNQG 2290

Query: 122  PDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQRAPSQ--SGPRQSST 179
              +   G  Q         Q  + PQ ++ L      + Q   P     +    P  ++ 
Sbjct: 2291 LTVVIQGQGQT------TGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTA 2344

Query: 180  SQAGTNQSGISQPVMWQLDMRQSGGSQPSM-----RQVGTSQSGTSQIGMSQPGTWQTGL 234
            + A T  + +S       + RQS  S P M     + +  +QS +     +QP T Q   
Sbjct: 2345 TTASTTTTTVSTTAAGTGEQRQSKLS-PQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPS- 2402

Query: 235  SQPVPRQPNKSP--PGMWQRG--MWQPGMSQQVPSQLGMRQPGTSQSSKNQ-TGMSHPG- 288
            +QP P+   +SP  P +  +     Q  +S  VPS+    QP  +QSSK Q    S P  
Sbjct: 2403 AQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSE---AQPTHAQSSKPQVAAQSQPQS 2459

Query: 289  --RGQPGIWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQP 327
              +GQ  +    PSQ  +     +QL   Q    Q   SQP
Sbjct: 2460 NVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQP 2500



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 41/137 (29%), Positives = 57/137 (41%), Gaps = 20/137 (14%)

Query: 116  QSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSEL-------VLSEASISQPGPPQRA 168
            QS +  P   QP   QP      + QP   PQS ++        V ++ ++S   P +  
Sbjct: 2385 QSSSVGPAEAQPQTAQPSA----QPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQ 2440

Query: 169  PSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQPG 228
            P+ +   QSS  Q    QS     V  Q  +R    SQ  +R      S  SQ+   Q  
Sbjct: 2441 PTHA---QSSKPQVAA-QSQPQSNVQGQSPVRVQSPSQTRIRP-----STPSQLSPGQQS 2491

Query: 229  TWQTGLSQPVPRQPNKS 245
              QT  SQP+P QP+ S
Sbjct: 2492 QVQTTTSQPIPIQPHTS 2508


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 55/207 (26%), Positives = 71/207 (34%), Gaps = 44/207 (21%)

Query: 107 PSMSQAGMRQSGTNLPDINQPGMKQPGTWQLGRSQPGMWPQSLSELVLSEASISQPGPPQ 166
           PS     +   G+ LP    PGM  PG++      PG  P  +   +        P P  
Sbjct: 218 PSAPNPVVSSLGSGLPP---PGMPPPGSFPPPVPPPGALPPGIPPAM-------PPPPMP 267

Query: 167 RAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTSQIGMSQ 226
              +  GP  + T  AG    G S P  +       G   P M Q+  +  G   +G   
Sbjct: 268 PGAAGHGPPSAGTPGAGHPGHGHSHPHPFP----PGGMPHPGMSQMQLAHHGPHGLGHPH 323

Query: 227 PGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQSSKNQTGMSH 286
            G   +G  QP PR P              PGM    P  +GM   G    S     M H
Sbjct: 324 AGPPGSG-GQPPPRPP--------------PGMPHPGPPPMGMPPRGPPFGSP----MGH 364

Query: 287 PG-------RGQPGIWEP----GPSQP 302
           PG       RG P +  P    GP +P
Sbjct: 365 PGPMPPHGMRGPPPLMPPHGYTGPPRP 391



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 4/87 (4%)

Query: 218 GTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTSQS 277
           G +  G    GT   G        P+  PPG    GM  PGMSQ   +  G    G   +
Sbjct: 269 GAAGHGPPSAGTPGAGHPGHGHSHPHPFPPG----GMPHPGMSQMQLAHHGPHGLGHPHA 324

Query: 278 SKNQTGMSHPGRGQPGIWEPGPSQPGL 304
               +G   P R  PG+  PGP   G+
Sbjct: 325 GPPGSGGQPPPRPPPGMPHPGPPPMGM 351


>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
          Length = 1938

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 81/363 (22%), Positives = 131/363 (36%), Gaps = 47/363 (12%)

Query: 3   PPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVP--------SQPGIRQPDTSQSCKNQT 54
           P G  Q   QQ    QQ PS   M     + ++P        +QP +      Q  +N +
Sbjct: 306 PQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFS 365

Query: 55  DMSQP----DANQSSLSDSNQTGIIQPSPSL-LGMNQMDMNQWSASLYEMNQVD-----M 104
            +S P       QS    S  + ++Q   +L  G   + M   +  L  M Q+      M
Sbjct: 366 PISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMM 425

Query: 105 KQPSMSQAGMRQSGTNLPDINQPGMKQPGTWQLG--RSQPGMWPQSLSELVLSEASISQP 162
             P+   AG +  G  L  + +  +  PG   L    +Q    P ++  ++LS+A   Q 
Sbjct: 426 PSPNSHAAGFK--GFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQK 483

Query: 163 GPPQRAPSQSGPRQSSTSQAGTNQ--SGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTS 220
              +R PS S    S T+  G++Q    +  P+   LD    GG   S    G      S
Sbjct: 484 KTSKR-PSSSKKADSCTNSEGSSQPEEQLKSPMAESLD----GGCSSSSEDQGERVRQLS 538

Query: 221 QIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPS----QLGMRQPGTSQ 276
               S   T++ G S+     P +       R    P   ++  S     + +   G  +
Sbjct: 539 GQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPK 598

Query: 277 SSKNQTGMSHPGRGQPG-IWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMR 335
            ++   G+        G + +PG    G SQ+D             P  +Q   S  G +
Sbjct: 599 VNEKTVGVIVSREAMTGRVEKPGGQDKG-SQED------------DPAATQRPPSNGGAK 645

Query: 336 QTS 338
           +TS
Sbjct: 646 ETS 648


>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
          Length = 1960

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 81/363 (22%), Positives = 131/363 (36%), Gaps = 47/363 (12%)

Query: 3   PPGMWQPGVQQPGISQQVPSHPDMSQPGMSQQVP--------SQPGIRQPDTSQSCKNQT 54
           P G  Q   QQ    QQ PS   M     + ++P        +QP +      Q  +N +
Sbjct: 306 PQGTQQGQQQQQPQQQQHPSQHVMQYTNAATKLPLQSQVGQYNQPEVPVRSPMQFHQNFS 365

Query: 55  DMSQP----DANQSSLSDSNQTGIIQPSPSL-LGMNQMDMNQWSASLYEMNQVD-----M 104
            +S P       QS    S  + ++Q   +L  G   + M   +  L  M Q+      M
Sbjct: 366 PISNPSPAASVVQSPSCSSTPSPLMQTGENLQCGQGSVPMGSRNRILQLMPQLSPTPSMM 425

Query: 105 KQPSMSQAGMRQSGTNLPDINQPGMKQPGTWQLG--RSQPGMWPQSLSELVLSEASISQP 162
             P+   AG +  G  L  + +  +  PG   L    +Q    P ++  ++LS+A   Q 
Sbjct: 426 PSPNSHAAGFK--GFGLEGVPEKRLTDPGLSSLSALSTQVANLPNTVQHMLLSDALTPQK 483

Query: 163 GPPQRAPSQSGPRQSSTSQAGTNQ--SGISQPVMWQLDMRQSGGSQPSMRQVGTSQSGTS 220
              +R PS S    S T+  G++Q    +  P+   LD    GG   S    G      S
Sbjct: 484 KTSKR-PSSSKKADSCTNSEGSSQPEEQLKSPMAESLD----GGCSSSSEDQGERVRQLS 538

Query: 221 QIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVPS----QLGMRQPGTSQ 276
               S   T++ G S+     P +       R    P   ++  S     + +   G  +
Sbjct: 539 GQSTSSDTTYKGGASEKAGSSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPK 598

Query: 277 SSKNQTGMSHPGRGQPG-IWEPGPSQPGLSQQDLNQLVLSQPGLSQPGRSQPSVSQMGMR 335
            ++   G+        G + +PG    G SQ+D             P  +Q   S  G +
Sbjct: 599 VNEKTVGVIVSREAMTGRVEKPGGQDKG-SQED------------DPAATQRPPSNGGAK 645

Query: 336 QTS 338
           +TS
Sbjct: 646 ETS 648


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/229 (20%), Positives = 89/229 (38%), Gaps = 20/229 (8%)

Query: 155  SEASISQPGPPQRAPSQSGPRQSSTSQAGTNQSGISQPVMWQLDMRQSGGSQPSMRQVGT 214
            S + +S+ GPP + P+   P +  T  A T+  G    V  +L       SQ        
Sbjct: 2242 STSPVSKKGPPLKTPASKSPSEGQT--ATTSPRGAKPSVKSELSPVARQTSQIGGSSKAP 2299

Query: 215  SQSGTSQIGMSQPGTWQTGLSQPVPRQPNKSPPGMWQRGMWQPGMSQQVP---------- 264
            S+SG+     S+P   Q  LS+P+ + P ++     + G+  P    Q+P          
Sbjct: 2300 SRSGSRDSTPSRPA--QQPLSRPI-QSPGRNSISPGRNGISPPNKLSQLPRTSSPSTAST 2356

Query: 265  -----SQLGMRQPGTSQSSKNQTGMSHPGRGQPGIWEPGPSQPGLSQQDLNQLVLSQPGL 319
                  ++    PG   S +N T  +   +    I     +  GL+Q +       +  L
Sbjct: 2357 KSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVEL 2416

Query: 320  SQPGRSQPSVSQMGMRQTSMDYFQIRHAEAGDCPEILRLIKELAACENM 368
            S+   ++ S S+    +  +   Q    +    P + R ++E A+ E++
Sbjct: 2417 SRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESL 2465



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 48/190 (25%), Positives = 79/190 (41%), Gaps = 34/190 (17%)

Query: 122  PDINQPGMKQPGTWQLGRSQP-GMWPQSLSELVLSEASISQPGPPQRAPSQSGPRQSSTS 180
            P +  P  K P   Q   + P G  P   SEL       SQ G   +APS+SG R S+ S
Sbjct: 2251 PPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPS 2310

Query: 181  QAGTNQSGISQPVMW----QLDMRQSGGSQP----------SMRQVGTSQSGTSQIGMSQ 226
            +    Q  +S+P+       +   ++G S P          S     T  SG+ ++  + 
Sbjct: 2311 RPA--QQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTS 2368

Query: 227  PG--------TWQTGLSQ---PVPRQPNKSPPGMWQRGMWQPGMSQQVPSQLGMRQPGTS 275
            PG        T QTGLS+    +PR  + S      +G+ Q         ++ + +  ++
Sbjct: 2369 PGRQMSQQNLTKQTGLSKNASSIPRSESAS------KGLNQMNNGNGANKKVELSRMSST 2422

Query: 276  QSSKNQTGMS 285
            +SS +++  S
Sbjct: 2423 KSSGSESDRS 2432



 Score = 36.6 bits (83), Expect = 0.047
 Identities = 51/259 (19%), Positives = 98/259 (37%), Gaps = 30/259 (11%)

Query: 11   VQQPGISQQVPSHPDMSQPGMSQQVPSQPGIRQPDTSQSCKNQTDMSQPDANQSSLSDSN 70
            +Q PG +   P    +S P    Q+P         T  S   +   + P    S  + + 
Sbjct: 2321 IQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTK 2380

Query: 71   QTGIIQPSPSL-------LGMNQMDMNQWSASLYEMNQVDMKQPSMSQAGMRQSGTNLPD 123
            QTG+ + + S+        G+NQM+    +    E++++         +  + SG+    
Sbjct: 2381 QTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRM---------SSTKSSGSESDR 2431

Query: 124  INQPGMKQPGTWQLGRSQPGMWPQSLSELVLSE--ASISQPGPPQRAPSQ------SGPR 175
              +P + +  T+      P +  + L E    E  +  S+P  P R+ +Q      S P 
Sbjct: 2432 SERPVLVRQSTFIKEAPSPTL-RRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPD 2490

Query: 176  QSSTSQAGTNQSGISQ-PVMWQLDMRQSGGSQPSMRQVGTSQS-GTSQIGMSQPGTWQTG 233
             S ++ +     G  + P      +  + G       +  S S   S++ +++ GTW+  
Sbjct: 2491 MSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKRE 2550

Query: 234  LSQPVPRQPNKSPPGMWQR 252
             S+     P  S    W+R
Sbjct: 2551 HSKHSSSLPRVS---TWRR 2566


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.126    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,213,796
Number of Sequences: 37866
Number of extensions: 1161158
Number of successful extensions: 6011
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 358
Number of HSP's that attempted gapping in prelim test: 4419
Number of HSP's gapped (non-prelim): 1110
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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