BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|6005948 WW domain-containing binding protein 4 [Homo sapiens] (376 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|6005948 WW domain-containing binding protein 4 [Homo sapiens] 766 0.0 gi|151301228 formin binding protein 3 [Homo sapiens] 64 3e-10 gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 60 3e-09 gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap... 60 3e-09 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 50 3e-06 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 50 3e-06 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 48 2e-05 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 48 2e-05 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 45 1e-04 gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo... 45 1e-04 gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ... 45 1e-04 gi|221219020 NYD-SP11 protein [Homo sapiens] 44 2e-04 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 44 2e-04 gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 43 4e-04 gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 43 4e-04 gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 43 4e-04 gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 43 4e-04 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 43 5e-04 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 43 5e-04 gi|115529449 upstream binding transcription factor, RNA polymera... 43 5e-04 gi|115529451 upstream binding transcription factor, RNA polymera... 43 5e-04 gi|7657671 upstream binding transcription factor, RNA polymerase... 43 5e-04 gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 43 5e-04 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 5e-04 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 5e-04 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 43 5e-04 gi|58331179 KIAA1688 protein [Homo sapiens] 43 5e-04 gi|104526627 triadin [Homo sapiens] 42 7e-04 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 42 0.001 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 42 0.001 >gi|6005948 WW domain-containing binding protein 4 [Homo sapiens] Length = 376 Score = 766 bits (1978), Expect = 0.0 Identities = 376/376 (100%), Positives = 376/376 (100%) Query: 1 MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEK 60 MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEK Sbjct: 1 MADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEK 60 Query: 61 ASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRK 120 ASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRK Sbjct: 61 ASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRK 120 Query: 121 KDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTY 180 KDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTY Sbjct: 121 KDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTY 180 Query: 181 YYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGV 240 YYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGV Sbjct: 181 YYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGV 240 Query: 241 STETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEI 300 STETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEI Sbjct: 241 STETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEI 300 Query: 301 KQEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFKEKTVTSLGVMADGVAPVFKKRR 360 KQEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFKEKTVTSLGVMADGVAPVFKKRR Sbjct: 301 KQEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFKEKTVTSLGVMADGVAPVFKKRR 360 Query: 361 TENGKSRNLRQRGDDQ 376 TENGKSRNLRQRGDDQ Sbjct: 361 TENGKSRNLRQRGDDQ 376 >gi|151301228 formin binding protein 3 [Homo sapiens] Length = 930 Score = 63.5 bits (153), Expect = 3e-10 Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 7/124 (5%) Query: 124 SKGRWVEGITSEGYHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYN 183 +K W E + +G YYY+ + S WEKP+ + ++ K W E S+ G YYYN Sbjct: 115 AKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYN 174 Query: 184 TETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTE 243 ++T ESRW KP +L + +N++ S+ H+ E+ +++ +T Sbjct: 175 SQTKESRWAKP-------KELEDLEGYQNTIVAGSLITKSNLHAMIKAEESSKQEECTTT 227 Query: 244 TEKP 247 + P Sbjct: 228 STAP 231 Score = 51.6 bits (122), Expect = 1e-06 Identities = 21/34 (61%), Positives = 25/34 (73%) Query: 163 TAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDD 196 + K++W E S DG TYYYNTET +S WEKPDD Sbjct: 113 SGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDD 146 Score = 33.1 bits (74), Expect = 0.42 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 11/97 (11%) Query: 219 ESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEK-----SIQ 273 ES+S+ HS S E+E ++ K K K K ++K+ SD E +K+K + Sbjct: 822 ESRSASEHSSS---AESERSYKKSKKHKKKSK-KRRHKSDSPESDAEREKDKKEKDRESE 877 Query: 274 KQNSLGSNEEKSKTLKK--SNPYGEWQEIKQEVESHE 308 K + +E K K+ KK G W E+ E Sbjct: 878 KDRTRQRSESKHKSPKKKTGKDSGNWDTSGSELSEGE 914 Score = 29.3 bits (64), Expect = 6.0 Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 6/63 (9%) Query: 104 TSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQWEKP------EGFQ 157 T S +K K ++ SK W E + G YYY+ + S+W KP EG+Q Sbjct: 136 TKQSTWEKPDDLKTPAEQLLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQ 195 Query: 158 GDL 160 + Sbjct: 196 NTI 198 >gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sapiens] Length = 858 Score = 60.1 bits (144), Expect = 3e-09 Identities = 53/222 (23%), Positives = 84/222 (37%), Gaps = 31/222 (13%) Query: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGAS 148 +L P++ +T P T++ P + W E + +G YYY+ S Sbjct: 60 MLMPAVPVTAATAPGADTASSAVAGT-------GPPRALWSEHVAPDGRIYYYNADDKQS 112 Query: 149 QWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKP---DDFIPHTSDLP 205 WEKP + + + W E S+ G YYYN ++ ESRW +P DD Sbjct: 113 VWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEA 172 Query: 206 SSKVNENSLGTLDESKSSDSHSD----------SDGEQEAEEGG--------VSTETEKP 247 + K + TL G E E GG + E+ Sbjct: 173 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQG 232 Query: 248 KIKFKEKNKNSDGGSDPETQKEKSIQKQNSLG---SNEEKSK 286 ++ E+ +S G P+ ++E+S + G SN EK+K Sbjct: 233 FLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAK 274 >gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sapiens] Length = 871 Score = 60.1 bits (144), Expect = 3e-09 Identities = 53/222 (23%), Positives = 84/222 (37%), Gaps = 31/222 (13%) Query: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGAS 148 +L P++ +T P T++ P + W E + +G YYY+ S Sbjct: 66 MLMPAVPVTAATAPGADTASSAVAGT-------GPPRALWSEHVAPDGRIYYYNADDKQS 118 Query: 149 QWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKP---DDFIPHTSDLP 205 WEKP + + + W E S+ G YYYN ++ ESRW +P DD Sbjct: 119 VWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEA 178 Query: 206 SSKVNENSLGTLDESKSSDSHSD----------SDGEQEAEEGG--------VSTETEKP 247 + K + TL G E E GG + E+ Sbjct: 179 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQG 238 Query: 248 KIKFKEKNKNSDGGSDPETQKEKSIQKQNSLG---SNEEKSK 286 ++ E+ +S G P+ ++E+S + G SN EK+K Sbjct: 239 FLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAK 280 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 50.1 bits (118), Expect = 3e-06 Identities = 74/334 (22%), Positives = 135/334 (40%), Gaps = 55/334 (16%) Query: 40 VAKRISEIKQKSLDKAKEEEKASKEFA-AMEAAALKAYQEDLKRLGLESEILEPSITP-- 96 V ++ E+ ++ K E+K SK + ME+ K + + L S+ L S++ Sbjct: 23 VPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNK 82 Query: 97 -VTSTIPPTSTS--NQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQWEKP 153 + ST ++T N++ ++ E+ KR K R L S AS+ Sbjct: 83 RIVSTKGKSATEYKNEEYQRSERNKRLDADRKIR---------------LSSSASR---- 123 Query: 154 EGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWE-KPDDFIPHTSDLPSSKVNEN 212 E ++ +KT V+ E ++ T G R + D +S +VN Sbjct: 124 EPYKNQPEKTCVRKRDPERRAKSP------TPDGSERIGLEVDRRASRSSQSSKEEVNSE 177 Query: 213 SLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSI 272 G+ E+ SS S + E EE GV + E+ + ++ ++ + D E ++E+ Sbjct: 178 EYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEE 237 Query: 273 QKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVSTSEADGGGE 332 +++ +E ++E E +E+ + + N+Y + SEA G Sbjct: 238 EEE----------------------EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275 Query: 333 PKVVFKEKTVTSLGVMADGVAPVFKKRRTENGKS 366 V F + +V S G DG K+R+ G S Sbjct: 276 ESVSFTDGSVRS-GSGTDGSDEKKKERKRARGIS 308 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 50.1 bits (118), Expect = 3e-06 Identities = 74/334 (22%), Positives = 135/334 (40%), Gaps = 55/334 (16%) Query: 40 VAKRISEIKQKSLDKAKEEEKASKEFA-AMEAAALKAYQEDLKRLGLESEILEPSITP-- 96 V ++ E+ ++ K E+K SK + ME+ K + + L S+ L S++ Sbjct: 23 VPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNK 82 Query: 97 -VTSTIPPTSTS--NQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQWEKP 153 + ST ++T N++ ++ E+ KR K R L S AS+ Sbjct: 83 RIVSTKGKSATEYKNEEYQRSERNKRLDADRKIR---------------LSSSASR---- 123 Query: 154 EGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWE-KPDDFIPHTSDLPSSKVNEN 212 E ++ +KT V+ E ++ T G R + D +S +VN Sbjct: 124 EPYKNQPEKTCVRKRDPERRAKSP------TPDGSERIGLEVDRRASRSSQSSKEEVNSE 177 Query: 213 SLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSI 272 G+ E+ SS S + E EE GV + E+ + ++ ++ + D E ++E+ Sbjct: 178 EYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEE 237 Query: 273 QKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVSTSEADGGGE 332 +++ +E ++E E +E+ + + N+Y + SEA G Sbjct: 238 EEE----------------------EEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275 Query: 333 PKVVFKEKTVTSLGVMADGVAPVFKKRRTENGKS 366 V F + +V S G DG K+R+ G S Sbjct: 276 ESVSFTDGSVRS-GSGTDGSDEKKKERKRARGIS 308 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 47.8 bits (112), Expect = 2e-05 Identities = 80/371 (21%), Positives = 146/371 (39%), Gaps = 58/371 (15%) Query: 23 NRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDL-- 80 +RP + + + K K +++ K +++ EE K E + ME A L A E+L Sbjct: 426 HRPPITISSKIQKPKVEAPKL--KVQHKFVEEIIEETKVEDEKSEMEEA-LTAITEELAV 482 Query: 81 -----KRLGLESEILEPSI---------TPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKG 126 K+ E + EP +PV +T P +KE++E ++ +++ +G Sbjct: 483 SMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEG 542 Query: 127 RWVEGITSEGYHYYYDLISGASQWEKPEGFQGDL-------KKTAVKTVWVEGLSEDGFT 179 + G G+S+ E+ E +G+ + A + VE SE+ T Sbjct: 543 AKSDQAEEGGSEK-----EGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 597 Query: 180 YYYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGG 239 +++ EKP+ S +P S V E + +S + + EE G Sbjct: 598 --KEELVADAKVEKPE---KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 652 Query: 240 VSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQE 299 ++ PK +EK K S P +K KS ++ + + K++ K E +E Sbjct: 653 ---KSPVPKSPVEEKGK-SPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKE 708 Query: 300 IK-----QEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFKEKTVTSLGVMADGVAP 354 +K ++VE EE ++P + + + KE+ V + + V Sbjct: 709 VKEAPKEEKVEKKEEKPKDVPEKK-------------KAESPVKEEAVAEVVTITKSVKV 755 Query: 355 VFKKRRTENGK 365 +K E GK Sbjct: 756 HLEKETKEEGK 766 Score = 41.2 bits (95), Expect = 0.002 Identities = 42/164 (25%), Positives = 67/164 (40%), Gaps = 9/164 (5%) Query: 211 ENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEK---PKIKFKEKNKNSDGGSDPETQ 267 E ++ +E K + + + E E EE K P++K +E K + G + E + Sbjct: 479 ELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE 538 Query: 268 KEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTE--NEYVSTS 325 +++ + + EK + +K E E + E E E E E +E V+T Sbjct: 539 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATK 598 Query: 326 EADGGGEPKVVFKEKT---VTSLGVMADGVAPVFKKRRTENGKS 366 E + + KV EK V V G +PV K E GKS Sbjct: 599 E-ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 641 Score = 32.7 bits (73), Expect = 0.55 Identities = 73/343 (21%), Positives = 127/343 (37%), Gaps = 72/343 (20%) Query: 38 ENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPV 97 E +A + E K+++ ++ +EE +A +E A + + +KA ++K E E E Sbjct: 478 EELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE--EEEGQEE 535 Query: 98 TSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGIT--------------------SEGY 137 + S+Q +E +K+ + +G EG T SE Sbjct: 536 EEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEV 595 Query: 138 HYYYDLISGASQWEKPEGFQGDLKKTAVKT-----VWVEGLSEDGFTYYYNT---ETGES 189 +L++ A EKPE + + K+ V+ V + E G + + E G+S Sbjct: 596 ATKEELVADAKV-EKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS 654 Query: 190 RWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSD---GEQEAEEGG------- 239 K S + S V E + + +S ++ S ++ GEQ+ EE Sbjct: 655 PVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK 714 Query: 240 ---VSTETEKPK--------------------------IKFKEKNKNSDGGSDPETQKEK 270 V + EKPK +K + + + G + +KEK Sbjct: 715 EEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEK 774 Query: 271 SIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLE 313 +K G +EE+ E + EVE EEV+ E Sbjct: 775 --EKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQE 815 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 47.8 bits (112), Expect = 2e-05 Identities = 80/371 (21%), Positives = 146/371 (39%), Gaps = 58/371 (15%) Query: 23 NRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDL-- 80 +RP + + + K K +++ K +++ EE K E + ME A L A E+L Sbjct: 50 HRPPITISSKIQKPKVEAPKL--KVQHKFVEEIIEETKVEDEKSEMEEA-LTAITEELAV 106 Query: 81 -----KRLGLESEILEPSI---------TPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKG 126 K+ E + EP +PV +T P +KE++E ++ +++ +G Sbjct: 107 SMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEG 166 Query: 127 RWVEGITSEGYHYYYDLISGASQWEKPEGFQGDL-------KKTAVKTVWVEGLSEDGFT 179 + G G+S+ E+ E +G+ + A + VE SE+ T Sbjct: 167 AKSDQAEEGGSEK-----EGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 221 Query: 180 YYYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGG 239 +++ EKP+ S +P S V E + +S + + EE G Sbjct: 222 --KEELVADAKVEKPE---KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKG 276 Query: 240 VSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQE 299 ++ PK +EK K S P +K KS ++ + + K++ K E +E Sbjct: 277 ---KSPVPKSPVEEKGK-SPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKE 332 Query: 300 IK-----QEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFKEKTVTSLGVMADGVAP 354 +K ++VE EE ++P + + + KE+ V + + V Sbjct: 333 VKEAPKEEKVEKKEEKPKDVPEKK-------------KAESPVKEEAVAEVVTITKSVKV 379 Query: 355 VFKKRRTENGK 365 +K E GK Sbjct: 380 HLEKETKEEGK 390 Score = 41.2 bits (95), Expect = 0.002 Identities = 42/164 (25%), Positives = 67/164 (40%), Gaps = 9/164 (5%) Query: 211 ENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEK---PKIKFKEKNKNSDGGSDPETQ 267 E ++ +E K + + + E E EE K P++K +E K + G + E + Sbjct: 103 ELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE 162 Query: 268 KEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTE--NEYVSTS 325 +++ + + EK + +K E E + E E E E E +E V+T Sbjct: 163 EDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATK 222 Query: 326 EADGGGEPKVVFKEKT---VTSLGVMADGVAPVFKKRRTENGKS 366 E + + KV EK V V G +PV K E GKS Sbjct: 223 E-ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKS 265 Score = 32.7 bits (73), Expect = 0.55 Identities = 73/343 (21%), Positives = 127/343 (37%), Gaps = 72/343 (20%) Query: 38 ENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPV 97 E +A + E K+++ ++ +EE +A +E A + + +KA ++K E E E Sbjct: 102 EELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE--EEEGQEE 159 Query: 98 TSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGIT--------------------SEGY 137 + S+Q +E +K+ + +G EG T SE Sbjct: 160 EEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEV 219 Query: 138 HYYYDLISGASQWEKPEGFQGDLKKTAVKT-----VWVEGLSEDGFTYYYNT---ETGES 189 +L++ A EKPE + + K+ V+ V + E G + + E G+S Sbjct: 220 ATKEELVADAKV-EKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS 278 Query: 190 RWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSD---GEQEAEEGG------- 239 K S + S V E + + +S ++ S ++ GEQ+ EE Sbjct: 279 PVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPK 338 Query: 240 ---VSTETEKPK--------------------------IKFKEKNKNSDGGSDPETQKEK 270 V + EKPK +K + + + G + +KEK Sbjct: 339 EEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEK 398 Query: 271 SIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLE 313 +K G +EE+ E + EVE EEV+ E Sbjct: 399 --EKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQE 439 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 45.1 bits (105), Expect = 1e-04 Identities = 66/295 (22%), Positives = 110/295 (37%), Gaps = 39/295 (13%) Query: 48 KQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTS 107 K K K ++EEK ++ A +KA QE L +L E E + + Sbjct: 316 KDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAK 375 Query: 108 NQQKEK--KEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGFQGDLKKTAV 165 +++E+ +EK++RKK K R E + EG + SQ E + LK Sbjct: 376 RKEEERLEQEKRERKKQKEKER-KERLKKEGK------LLTKSQREARARAEATLKLLQA 428 Query: 166 KTVWVEGLSEDGFTYYYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDS 225 + V V D +P + K + L+ + S+S Sbjct: 429 QGVEVPS----------------------KDSLPKKRPIYEDKKRKKIPQQLESKEVSES 466 Query: 226 HSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKS 285 + E+G E P ++ +E+ D G D + + S ++ + N+ Sbjct: 467 MELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLD-DWEAMASDEETEKVEGNKVHI 525 Query: 286 KTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFKEK 340 + K NP E ++E E EE D E E E + ++G E + V EK Sbjct: 526 EV--KENP-----EEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEK 573 Score = 44.3 bits (103), Expect = 2e-04 Identities = 58/243 (23%), Positives = 100/243 (41%), Gaps = 30/243 (12%) Query: 145 SGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDFIPHTSDL 204 +GA++ ++P+ +G KK K + ED + E++ K D T + Sbjct: 29 AGAAKEQEPQKSKGKKKKEKKK----QDFDEDDILKELEELSLEAQGIKADR---ETVAV 81 Query: 205 PSSKVNENSLGTLDESKSSD-----SHSDSDGEQEAEEGGVSTETEKPKIK-FKEKNKNS 258 ++ NE + D+ K S D+D E+ ++ S +T KPK++ + + + Sbjct: 82 KPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDD 141 Query: 259 DGGSDPETQK---EKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELP 315 D P+ K +KS +K + +E+ SK +K E I ES +E D L Sbjct: 142 DFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIK------ERSRINSSGESGDESDEFLQ 195 Query: 316 STENEYVSTSE------ADGGGEPKVVFKEKTVTSLGVMADGVAPVFKKRRTENGKSRNL 369 S + + + G + FK KTV A+ KKR E K R L Sbjct: 196 SRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQ--KKAEKKERERKKRDEEKAKLRKL 253 Query: 370 RQR 372 +++ Sbjct: 254 KEK 256 Score = 39.3 bits (90), Expect = 0.006 Identities = 65/303 (21%), Positives = 116/303 (38%), Gaps = 40/303 (13%) Query: 22 DNRPSVEFHERGKNHKENVAKRISE--IKQKSLDKAKEEEKASKEFAAMEAAAL-KAYQE 78 + R E ER K +E AKR E ++Q+ ++ K++EK KE E L K+ +E Sbjct: 355 EERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQRE 414 Query: 79 DLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYH 138 R ++L+ V P + +++ E KKRKK P + + S+ Sbjct: 415 ARARAEATLKLLQAQGVEV----PSKDSLPKKRPIYEDKKRKKIPQQ------LESKEVS 464 Query: 139 YYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDFI 198 +L + E QG +K ED + G WE Sbjct: 465 ESMELCAAVEVME-----QGVPEKEETPPPVEPEEEED------TEDAGLDDWEAM---- 509 Query: 199 PHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNS 258 SD + KV N + + + + + E+E EE S E E E+ S Sbjct: 510 --ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEE---SEEEE-------EEEGES 557 Query: 259 DGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTE 318 +G E ++ S +K + +++ SK + + Y + +E ++++ + Sbjct: 558 EGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRR 617 Query: 319 NEY 321 E+ Sbjct: 618 LEH 620 Score = 36.2 bits (82), Expect = 0.049 Identities = 67/316 (21%), Positives = 128/316 (40%), Gaps = 60/316 (18%) Query: 49 QKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSN 108 QKS K K+E+K ++F E LK +L+ L LE++ ++ V + PT + Sbjct: 38 QKSKGKKKKEKK-KQDFD--EDDILK----ELEELSLEAQGIKADRETVA--VKPTENNE 88 Query: 109 QQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGFQGDLKKTAVKTV 168 ++ K+KKK+ + K + + + E+ E KKTA V Sbjct: 89 EEFTSKDKKKKGQKGKKQSFDD-----------------NDSEELEDKDSKSKKTAKPKV 131 Query: 169 WVEGLSEDGFTYYYNTETGESRWEKPD---DFIPHTSDLPSSKVNENSLGTLDESKSSDS 225 + S+D + + + + +K + D D S K+ E S + S +S Sbjct: 132 EMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDED-NSKKIKERS----RINSSGES 186 Query: 226 HSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQK--QNSLGSNEE 283 +SD ++ +G + KP + N++ D +T +K +K + +EE Sbjct: 187 GDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEE 246 Query: 284 KSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFKEKTVT 343 K+K K K+E+E+ ++ + ++ + F+E+TV Sbjct: 247 KAKLRKLKE--------KEELETGKKDQSKQKESQRK----------------FEEETVK 282 Query: 344 SLGVMADGVAPVFKKR 359 S + GV P +++ Sbjct: 283 SKVTVDTGVIPASEEK 298 Score = 32.0 bits (71), Expect = 0.93 Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 11/99 (11%) Query: 38 ENVAKRISEIKQKSLDKAKEEEKAS----KEFAAMEAAALKAYQEDLKRLGLESEILEPS 93 + VA++ +E K++ K ++EEKA KE +E ++ + E E ++ Sbjct: 226 KTVAQKKAEKKERERKK-RDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSK 284 Query: 94 ITPVTSTIPP------TSTSNQQKEKKEKKKRKKDPSKG 126 +T T IP T T+ + + +KKK+ K KG Sbjct: 285 VTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG 323 >gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo sapiens] Length = 530 Score = 44.7 bits (104), Expect = 1e-04 Identities = 67/302 (22%), Positives = 116/302 (38%), Gaps = 26/302 (8%) Query: 19 WIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKE----EEKASKE--FAAMEAAA 72 W DN P V+F + K++ A E+++K +KE EEKAS E A++ Sbjct: 82 WEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITT 141 Query: 73 LKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGI 132 KA + KR E ++ VT+ + K + K P K R + Sbjct: 142 PKAARRGRKRKA-EKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIP-KPRGRPKM 199 Query: 133 TSEGYHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWE 192 + D+I+ + +K + KK K E+G + E + Sbjct: 200 VKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKK-------DEEG-------QKEEDKPR 245 Query: 193 KPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEG-GVSTETEKPKIKF 251 K D ++ S + N G S S + D +GE++ + G T + +K Sbjct: 246 KEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKG 305 Query: 252 KEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKK--SNPYGEWQEIKQEVESHEE 309 + + + +D E Q E Q ++ G E K KK ++ Q I E+++ + Sbjct: 306 QHEKEAADRKRKQEEQMETEQQNKDE-GKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLK 364 Query: 310 VD 311 +D Sbjct: 365 ID 366 >gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo sapiens] Length = 530 Score = 44.7 bits (104), Expect = 1e-04 Identities = 67/302 (22%), Positives = 116/302 (38%), Gaps = 26/302 (8%) Query: 19 WIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKE----EEKASKE--FAAMEAAA 72 W DN P V+F + K++ A E+++K +KE EEKAS E A++ Sbjct: 82 WEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITT 141 Query: 73 LKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGI 132 KA + KR E ++ VT+ + K + K P K R + Sbjct: 142 PKAARRGRKRKA-EKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIP-KPRGRPKM 199 Query: 133 TSEGYHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWE 192 + D+I+ + +K + KK K E+G + E + Sbjct: 200 VKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKK-------DEEG-------QKEEDKPR 245 Query: 193 KPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEG-GVSTETEKPKIKF 251 K D ++ S + N G S S + D +GE++ + G T + +K Sbjct: 246 KEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKG 305 Query: 252 KEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKK--SNPYGEWQEIKQEVESHEE 309 + + + +D E Q E Q ++ G E K KK ++ Q I E+++ + Sbjct: 306 QHEKEAADRKRKQEEQMETEQQNKDE-GKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLK 364 Query: 310 VD 311 +D Sbjct: 365 ID 366 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 43.9 bits (102), Expect = 2e-04 Identities = 37/153 (24%), Positives = 71/153 (46%), Gaps = 11/153 (7%) Query: 190 RWEKPDD-FIPHTSDLPSSK-VNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKP 247 R +KP + F ++ S + +E LDE + +S S + E+ EE E E+ Sbjct: 2205 RGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEE----EEREEE 2260 Query: 248 KIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESH 307 +++ +E+ + + E +EK ++K+ ++K K ++ E E K+E+ S Sbjct: 2261 EVREEEEERKEE-----EEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315 Query: 308 EEVDLELPSTENEYVSTSEADGGGEPKVVFKEK 340 EE + E E + E + E +++ KEK Sbjct: 2316 EETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348 Score = 29.6 bits (65), Expect = 4.6 Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 21/96 (21%) Query: 31 ERGKNHKENVAKRISEI-KQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEI 89 E ++ E + + E+ KQ+SL +EEE+ +E E + + + G E ++ Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV 2280 Query: 90 LEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSK 125 +KE++EKKK+KK+ K Sbjct: 2281 --------------------EKEEEEKKKKKKEKKK 2296 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 43.9 bits (102), Expect = 2e-04 Identities = 66/308 (21%), Positives = 116/308 (37%), Gaps = 43/308 (13%) Query: 26 SVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRL-- 83 S+ F +N+ +N +K S +K K K+ +K +K+ + E+ K ++D K++ Sbjct: 258 SINFDAWLRNYSQNNSKNYS-LKYTKYTK-KDTKKNAKKSSDAESEDSKDAKKDSKKVKK 315 Query: 84 GLESEILEPSI---TPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYY 140 ++ + + + T T S ++ KK+KKK KKD K Sbjct: 316 NVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKK-------------- 361 Query: 141 YDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDFIPH 200 D KK T G ++D N + +K D Sbjct: 362 ------------------DTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKI 403 Query: 201 TSDLPSSKVNENSLGTLDESKSS-DSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 T S E+ DE K DS +D+ + +E ++E K K Sbjct: 404 TFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKK 463 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYG-EWQEIKQEVESHEEVDLELPSTE 318 G D + +K K+N+ + E LKK + E + K++++ D E ST+ Sbjct: 464 GKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTE--STD 521 Query: 319 NEYVSTSE 326 E+ +S+ Sbjct: 522 AEFDESSK 529 Score = 37.0 bits (84), Expect = 0.029 Identities = 67/331 (20%), Positives = 122/331 (36%), Gaps = 36/331 (10%) Query: 2 ADYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEKA 61 A+Y KS+ +K K S + K E KR +E + L + E E++ Sbjct: 113 AEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQS 172 Query: 62 SKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKK 121 K ++ E + + + + + + + T+T T N K+ ++ K Sbjct: 173 KKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNT-EFLHTKNNPKKDLKRSKTSN 231 Query: 122 DPSKGRWVEGITSEG-YHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDG--- 177 DP + I SE + + ++ G S E D W+ S++ Sbjct: 232 DP-----ISEICSENSLNVDFLMLVGQSD---DESINFD--------AWLRNYSQNNSKN 275 Query: 178 ----FTYYYNTETGESRWEKPDDFIPHTSDLP--SSKVNENSLGTLDESKSSDSHSD--S 229 +T Y +T ++ + D + D S KV +N K D D Sbjct: 276 YSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNV-------KKDDKKKDVKK 328 Query: 230 DGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLK 289 D E E G S + K K K+K K D D + E + + S+ LK Sbjct: 329 DTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLK 388 Query: 290 KSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 K++ + ++ +++ + + EL S E++ Sbjct: 389 KASKNDDKKKDAKKITFSTDSESELESKESQ 419 Score = 34.3 bits (77), Expect = 0.19 Identities = 51/247 (20%), Positives = 96/247 (38%), Gaps = 43/247 (17%) Query: 31 ERGKNHKENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEIL 90 ++ K+ K+ SE + +S + K+E+K K+ ++K +E Sbjct: 395 DKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEES----------- 443 Query: 91 EPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQW 150 T S S ++ EKK KK KKD K + S +L Sbjct: 444 ----TDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHS 499 Query: 151 EKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPD--DFIPHTSDLPSSK 208 ++ +G + D+KK A K +TE+ ++ +++ F T S Sbjct: 500 KEKKGSKKDIKKDARK----------------DTESTDAEFDESSKTGFKTSTKIKGSDT 543 Query: 209 VNENSL------GTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGS 262 +E SL +DES + ++S +G + +S++ K F EK + + G Sbjct: 544 ESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSK----KTTFNEKGEKASTGR 599 Query: 263 DPETQKE 269 P ++++ Sbjct: 600 VPPSREK 606 Score = 32.3 bits (72), Expect = 0.71 Identities = 27/113 (23%), Positives = 51/113 (45%), Gaps = 14/113 (12%) Query: 218 DESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKN-------SDGGSDPETQKEK 270 D K S++ + ++ E + E K K ++N S ++PE+Q K Sbjct: 130 DSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSK 189 Query: 271 SIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVS 323 ++ K N +++ SK KK+N E+ K ++ + DL+ T N+ +S Sbjct: 190 TVSK-NCSQKDKKDSKNSKKTNT--EFLHTK----NNPKKDLKRSKTSNDPIS 235 >gi|13540523 nucleosomal binding protein 1 [Homo sapiens] Length = 282 Score = 43.1 bits (100), Expect = 4e-04 Identities = 59/265 (22%), Positives = 95/265 (35%), Gaps = 76/265 (28%) Query: 28 EFHERGKNHKENVA------KRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLK 81 +++E KN + + K I E+K+++++ A E+ KE A E +K +ED K Sbjct: 75 DYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAE---VKNEEEDQK 131 Query: 82 RLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYY 141 +Q +EK E K KD KG +G Sbjct: 132 E----------------------DEEDQNEEKGEAGKEDKD-EKGE------EDGKEDKN 162 Query: 142 DLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDFIPHT 201 G EK +G +G+ K G EDG E GE E+ D Sbjct: 163 GNEKGEDAKEKEDGKKGEDGK---------GNGEDG------KEKGEDEKEEED------ 201 Query: 202 SDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGG 261 ++ D + DG+++ ++ K K +E K +GG Sbjct: 202 -----------------RKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGG 244 Query: 262 SDPETQKEKSIQKQNSLGSNEEKSK 286 ++ E KEK K+ G E++ K Sbjct: 245 NEEEAGKEKEDLKEEEEGKEEDEIK 269 >gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo sapiens] Length = 1094 Score = 43.1 bits (100), Expect = 4e-04 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 2/130 (1%) Query: 180 YYYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGG 239 +Y +E E + D + + G +E S DS S+ D E E G Sbjct: 675 FYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESGL 734 Query: 240 VSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQE 299 + T K K K K+ + DG + E +K K+ N S+ E S + +S E + Sbjct: 735 ENKRTAKRNSKAKGKSDSEDG--EKENEKSKTSDSSNDESSSIEDSSSDSESESEPESES 792 Query: 300 IKQEVESHEE 309 + V +E Sbjct: 793 ESRRVTKEKE 802 Score = 39.3 bits (90), Expect = 0.006 Identities = 27/125 (21%), Positives = 59/125 (47%), Gaps = 4/125 (3%) Query: 219 ESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSL 278 ES+ + SDS + E+E G S E + +E + N D D ++++ +++ L Sbjct: 678 ESEEEEDSSDSSSDSESESGSESGEQGE---SGEEGDSNEDSSEDSSSEQDSESGRESGL 734 Query: 279 GSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFK 338 N+ +K K+ + ++ ++E E + D + + S+S+++ EP+ + Sbjct: 735 -ENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESE 793 Query: 339 EKTVT 343 + VT Sbjct: 794 SRRVT 798 Score = 33.9 bits (76), Expect = 0.25 Identities = 54/197 (27%), Positives = 78/197 (39%), Gaps = 49/197 (24%) Query: 52 LDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQK 111 ++ AKE A K A E +A K Y E E + S + S S S +Q Sbjct: 654 IELAKEWTPAGK--AKQENSAKKFYSES-------EEEEDSSDSSSDSESESGSESGEQG 704 Query: 112 EKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGASQWEKPEGFQGDL--KKTAVKTVW 169 E E+ +D S+ +S+ + G + L K+TA + Sbjct: 705 ESGEEGDSNEDSSE-------------------DSSSEQDSESGRESGLENKRTAKRNSK 745 Query: 170 VEGLSEDGFTYYYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDS 229 +G S+ +E GE EK TSD SS +S+ E SSDS S+S Sbjct: 746 AKGKSD--------SEDGEKENEKSK-----TSD--SSNDESSSI----EDSSSDSESES 786 Query: 230 DGEQEAEEGGVSTETEK 246 + E E+E V+ E EK Sbjct: 787 EPESESESRRVTKEKEK 803 >gi|91208418 transcription elongation regulator 1 isoform 2 [Homo sapiens] Length = 1077 Score = 43.1 bits (100), Expect = 4e-04 Identities = 55/226 (24%), Positives = 88/226 (38%), Gaps = 32/226 (14%) Query: 77 QEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEG 136 QE ++ LE +I EP P +P T + +++ K+ K++P + E +T E Sbjct: 440 QELKEKEKLEEKIKEPIKEPSEEPLP-METEEEDPKEEPIKEIKEEPKE----EEMTEE- 493 Query: 137 YHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDD 196 A+Q KP + T VW + D ++YN T S W++PDD Sbjct: 494 --------EKAAQKAKPVA-TAPIPGTPWCVVW----TGDERVFFYNPTTRLSMWDRPDD 540 Query: 197 FI------------PHTSDLPSSKVNENSLGT-LDESKSSDSHSDSDGEQEAEEGGVSTE 243 I PH + K + T L K S S EQE E E Sbjct: 541 LIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDE 600 Query: 244 TEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLK 289 K K + ++ NK+ D + + E ++ ++ E + K K Sbjct: 601 PVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFK 646 Score = 42.7 bits (99), Expect = 5e-04 Identities = 33/106 (31%), Positives = 44/106 (41%), Gaps = 20/106 (18%) Query: 169 WVEGLSEDGFTYYYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSD 228 W E + DG TYYYN T ES WEKP + K E + E S Sbjct: 414 WTEYKTADGKTYYYNNRTLESTWEKPQEL----------KEKEKLEEKIKEPIKEPSEEP 463 Query: 229 SDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQK 274 E E E+ E+P + KE+ K + T++EK+ QK Sbjct: 464 LPMETEEED-----PKEEPIKEIKEEPKEEE-----MTEEEKAAQK 499 Score = 41.6 bits (96), Expect = 0.001 Identities = 16/28 (57%), Positives = 18/28 (64%) Query: 168 VWVEGLSEDGFTYYYNTETGESRWEKPD 195 +WVE + DG YYYN T ES W KPD Sbjct: 136 IWVENKTPDGKVYYYNARTRESAWTKPD 163 Score = 34.3 bits (77), Expect = 0.19 Identities = 14/33 (42%), Positives = 20/33 (60%) Query: 123 PSKGRWVEGITSEGYHYYYDLISGASQWEKPEG 155 P++ WVE T +G YYY+ + S W KP+G Sbjct: 132 PTEEIWVENKTPDGKVYYYNARTRESAWTKPDG 164 >gi|21327715 transcription elongation regulator 1 isoform 1 [Homo sapiens] Length = 1098 Score = 43.1 bits (100), Expect = 4e-04 Identities = 55/226 (24%), Positives = 88/226 (38%), Gaps = 32/226 (14%) Query: 77 QEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEG 136 QE ++ LE +I EP P +P T + +++ K+ K++P + E +T E Sbjct: 461 QELKEKEKLEEKIKEPIKEPSEEPLP-METEEEDPKEEPIKEIKEEPKE----EEMTEE- 514 Query: 137 YHYYYDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDD 196 A+Q KP + T VW + D ++YN T S W++PDD Sbjct: 515 --------EKAAQKAKPVA-TAPIPGTPWCVVW----TGDERVFFYNPTTRLSMWDRPDD 561 Query: 197 FI------------PHTSDLPSSKVNENSLGT-LDESKSSDSHSDSDGEQEAEEGGVSTE 243 I PH + K + T L K S S EQE E E Sbjct: 562 LIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDE 621 Query: 244 TEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLK 289 K K + ++ NK+ D + + E ++ ++ E + K K Sbjct: 622 PVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFK 667 Score = 42.7 bits (99), Expect = 5e-04 Identities = 33/106 (31%), Positives = 44/106 (41%), Gaps = 20/106 (18%) Query: 169 WVEGLSEDGFTYYYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSD 228 W E + DG TYYYN T ES WEKP + K E + E S Sbjct: 435 WTEYKTADGKTYYYNNRTLESTWEKPQEL----------KEKEKLEEKIKEPIKEPSEEP 484 Query: 229 SDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQK 274 E E E+ E+P + KE+ K + T++EK+ QK Sbjct: 485 LPMETEEED-----PKEEPIKEIKEEPKEEE-----MTEEEKAAQK 520 Score = 41.6 bits (96), Expect = 0.001 Identities = 16/28 (57%), Positives = 18/28 (64%) Query: 168 VWVEGLSEDGFTYYYNTETGESRWEKPD 195 +WVE + DG YYYN T ES W KPD Sbjct: 136 IWVENKTPDGKVYYYNARTRESAWTKPD 163 Score = 34.3 bits (77), Expect = 0.19 Identities = 14/33 (42%), Positives = 20/33 (60%) Query: 123 PSKGRWVEGITSEGYHYYYDLISGASQWEKPEG 155 P++ WVE T +G YYY+ + S W KP+G Sbjct: 132 PTEEIWVENKTPDGKVYYYNARTRESAWTKPDG 164 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 42.7 bits (99), Expect = 5e-04 Identities = 75/323 (23%), Positives = 126/323 (39%), Gaps = 79/323 (24%) Query: 30 HERGKNHKENVAKRISEI-KQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESE 88 HER K H+E K E +QK + A+E + ++ +E K +E R Sbjct: 119 HERRKRHREEQDKARREWERQKRREMAREHSRRERD--RLEQLERKRERERKMR------ 170 Query: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHY----YYDLI 144 +Q+E+KE+++R ++ K R S + Y D + Sbjct: 171 ----------------EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV 214 Query: 145 SGASQWEKP------EGFQ-GDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDF 197 AS W + E F+ GD +K + E E R D Sbjct: 215 K-ASHWSRSPPRPPRERFELGDGRKPVKE------------------EKMEER-----DL 250 Query: 198 IPHTSDLPSSKVNENSLGTLD-ESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNK 256 + D+ S+ +S + ES S + + E+E EEG S E+E+ + +E+ + Sbjct: 251 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE--EEEEEEE 308 Query: 257 NSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN-------PYGEW-QEIKQEVESHE 308 + GS+ E E+S ++ S EE S+ ++ N P + ++ + E+ E Sbjct: 309 EEETGSNSEEASEQSAEEV----SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 364 Query: 309 EVDLELPS----TENEYVSTSEA 327 EV P TE +YV S A Sbjct: 365 EVGEGTPQSSALTEGDYVPDSPA 387 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 42.7 bits (99), Expect = 5e-04 Identities = 75/323 (23%), Positives = 126/323 (39%), Gaps = 79/323 (24%) Query: 30 HERGKNHKENVAKRISEI-KQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESE 88 HER K H+E K E +QK + A+E + ++ +E K +E R Sbjct: 129 HERRKRHREEQDKARREWERQKRREMAREHSRRERD--RLEQLERKRERERKMR------ 180 Query: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHY----YYDLI 144 +Q+E+KE+++R ++ K R S + Y D + Sbjct: 181 ----------------EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV 224 Query: 145 SGASQWEKP------EGFQ-GDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDF 197 AS W + E F+ GD +K + E E R D Sbjct: 225 K-ASHWSRSPPRPPRERFELGDGRKPVKE------------------EKMEER-----DL 260 Query: 198 IPHTSDLPSSKVNENSLGTLD-ESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNK 256 + D+ S+ +S + ES S + + E+E EEG S E+E+ + +E+ + Sbjct: 261 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE--EEEEEEE 318 Query: 257 NSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN-------PYGEW-QEIKQEVESHE 308 + GS+ E E+S ++ S EE S+ ++ N P + ++ + E+ E Sbjct: 319 EEETGSNSEEASEQSAEEV----SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374 Query: 309 EVDLELPS----TENEYVSTSEA 327 EV P TE +YV S A Sbjct: 375 EVGEGTPQSSALTEGDYVPDSPA 397 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 42.7 bits (99), Expect = 5e-04 Identities = 70/312 (22%), Positives = 124/312 (39%), Gaps = 57/312 (18%) Query: 21 ADNRPSVEFHERGKNHKENVAKRISEIKQKSL----------DKAKEEEKASKEFAAMEA 70 ++ +P E ERGK + KR EI Q+S+ D+ K + + ME Sbjct: 430 SERKPGGEREERGKLPES--PKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK 487 Query: 71 AA----LKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKG 126 +K ED KR E E+ E PP +T N K+ K + + KK P G Sbjct: 488 KEKLMWIKKAAEDQKRY--ERELSE-------MRAPPAAT-NSSKKMKFQGEPKKPPMNG 537 Query: 127 --RWVEGITSEGYHYYYDL----ISGASQWEKPEGFQGD-LKKTAVKT---------VWV 170 ++ + + S G + L + S+W++ Q + KK A + +WV Sbjct: 538 YQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWV 597 Query: 171 EGLSEDGFTYY--YNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHS- 227 + LS Y Y + +S + P+ K + +L + ES+ D Sbjct: 598 KSLSPQDRAAYKEYISNKRKSMTKLRG---------PNPKSSRTTLQSKSESEEDDEEDE 648 Query: 228 ---DSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEK 284 D D E+E +E G S+E + ++++ DG + E +++ + + + E Sbjct: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708 Query: 285 SKTLKKSNPYGE 296 + S+ G+ Sbjct: 709 EGSSSSSSSSGD 720 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 42.7 bits (99), Expect = 5e-04 Identities = 70/312 (22%), Positives = 124/312 (39%), Gaps = 57/312 (18%) Query: 21 ADNRPSVEFHERGKNHKENVAKRISEIKQKSL----------DKAKEEEKASKEFAAMEA 70 ++ +P E ERGK + KR EI Q+S+ D+ K + + ME Sbjct: 430 SERKPGGEREERGKLPES--PKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK 487 Query: 71 AA----LKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKG 126 +K ED KR E E+ E PP +T N K+ K + + KK P G Sbjct: 488 KEKLMWIKKAAEDQKRY--ERELSE-------MRAPPAAT-NSSKKMKFQGEPKKPPMNG 537 Query: 127 --RWVEGITSEGYHYYYDL----ISGASQWEKPEGFQGD-LKKTAVKT---------VWV 170 ++ + + S G + L + S+W++ Q + KK A + +WV Sbjct: 538 YQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWV 597 Query: 171 EGLSEDGFTYY--YNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHS- 227 + LS Y Y + +S + P+ K + +L + ES+ D Sbjct: 598 KSLSPQDRAAYKEYISNKRKSMTKLRG---------PNPKSSRTTLQSKSESEEDDEEDE 648 Query: 228 ---DSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEK 284 D D E+E +E G S+E + ++++ DG + E +++ + + + E Sbjct: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708 Query: 285 SKTLKKSNPYGE 296 + S+ G+ Sbjct: 709 EGSSSSSSSSGD 720 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 42.7 bits (99), Expect = 5e-04 Identities = 70/312 (22%), Positives = 124/312 (39%), Gaps = 57/312 (18%) Query: 21 ADNRPSVEFHERGKNHKENVAKRISEIKQKSL----------DKAKEEEKASKEFAAMEA 70 ++ +P E ERGK + KR EI Q+S+ D+ K + + ME Sbjct: 467 SERKPGGEREERGKLPES--PKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEK 524 Query: 71 AA----LKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKG 126 +K ED KR E E+ E PP +T N K+ K + + KK P G Sbjct: 525 KEKLMWIKKAAEDQKRY--ERELSE-------MRAPPAAT-NSSKKMKFQGEPKKPPMNG 574 Query: 127 --RWVEGITSEGYHYYYDL----ISGASQWEKPEGFQGD-LKKTAVKT---------VWV 170 ++ + + S G + L + S+W++ Q + KK A + +WV Sbjct: 575 YQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWV 634 Query: 171 EGLSEDGFTYY--YNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHS- 227 + LS Y Y + +S + P+ K + +L + ES+ D Sbjct: 635 KSLSPQDRAAYKEYISNKRKSMTKLRG---------PNPKSSRTTLQSKSESEEDDEEDE 685 Query: 228 ---DSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEK 284 D D E+E +E G S+E + ++++ DG + E +++ + + + E Sbjct: 686 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 745 Query: 285 SKTLKKSNPYGE 296 + S+ G+ Sbjct: 746 EGSSSSSSSSGD 757 >gi|56676397 ankyrin repeat domain 11 [Homo sapiens] Length = 2663 Score = 42.7 bits (99), Expect = 5e-04 Identities = 63/328 (19%), Positives = 127/328 (38%), Gaps = 44/328 (13%) Query: 23 NRPSVEFHERGKNHKENVAKRISEI-KQKSLDK-AKEEEKASKEFAAMEAAALKAYQEDL 80 N+ E + K+ KE + E K+KS D+ +K E+K + + K ++ED Sbjct: 740 NKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDK 799 Query: 81 KRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYY 140 ++L E E S NQ E ++ K D + RW ++ + + Sbjct: 800 EKLKKEKVYREDS------AFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDF- 852 Query: 141 YDLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESR-------WEK 193 G W+ P D+K +V + +E + ED ++ E R +K Sbjct: 853 ----KGEDSWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKK 908 Query: 194 PDDFIPHTSDLPSSKVNENS-----LGTLDESKSSDSHSDSDGE------QEAEEGGVS- 241 D++ S+ + ++ L D+ + + + D + +E +G Sbjct: 909 DRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKP 968 Query: 242 TETEKPKIK-------FKEKNKNSDG-GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNP 293 E + ++K FK+K+ G G +P + + +K+ G ++E+ + K Sbjct: 969 EEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKPE-- 1026 Query: 294 YGEWQEIKQEVESHEEVDLELPSTENEY 321 ++E + + E+ LE + E+ Sbjct: 1027 --RYKEKSSDKDKSEKSILEKCQKDKEF 1052 Score = 42.7 bits (99), Expect = 5e-04 Identities = 77/355 (21%), Positives = 129/355 (36%), Gaps = 58/355 (16%) Query: 22 DNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLK 81 D R + G++ KE V ++ E K K ++ E+ K K+ A++++ K ++ L Sbjct: 1183 DRRKDRGAADAGRDKKEKVFEKHKEKKDK---ESTEKYKDRKDRASVDSTQDKKNKQKLP 1239 Query: 82 RLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYY 141 + E + S+++ K+ K R D K +E + E H Y Sbjct: 1240 EKAEKKHAAEDK-----AKSKHKEKSDKEHSKERKSSRSADAEKSL-LEKLEEEALHEYR 1293 Query: 142 DLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDFIPHT 201 + + + F + E G T + S E P D P Sbjct: 1294 EDSNDKISEVSSDSF-------------TDRGQEPGLTAFLEV----SFTEPPGDDKPRE 1336 Query: 202 SDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGG 261 S K+ E S S SH + E+ K KEK + + G Sbjct: 1337 SACLPEKLKEKERHRHSSSSSKKSH----------------DRERAK---KEKAEKKEKG 1377 Query: 262 SDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEY 321 D KE +K + + K +++ YG +K ++E + +EL STE + Sbjct: 1378 ED---YKEGGSRKDSG-----QYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKD 1429 Query: 322 VSTSEADGGGEPKVVFKEKTVTSLGVMADGVAPVFKKRRTENGKSRNLRQRGDDQ 376 + SE EP EK + G A + KKR K R+ ++R D+ Sbjct: 1430 KNDSER----EPSKKI-EKELKPYGSSAINILKEKKKREKHREKWRDEKERHRDR 1479 Score = 37.4 bits (85), Expect = 0.022 Identities = 74/319 (23%), Positives = 123/319 (38%), Gaps = 56/319 (17%) Query: 34 KNHKENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESEILEPS 93 K++ +N + + L +EE AS E L A+ + Sbjct: 389 KSYTKNNTIAPKKASHRILSDTSDEEDASVTVGTGEKLRLSAH----------------T 432 Query: 94 ITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVE-GITSEGYHYYYDLISGASQWEK 152 I P + T P S + QQKEK + KK++K +KGR V G S+ + S S+ E Sbjct: 433 ILPGSKTREP-SNAKQQKEKNKVKKKRKKETKGREVRFGKRSDKF------CSSESESES 485 Query: 153 PE---------GFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDFIPHTSD 203 E G G LK + + S + + + ++ + P HT Sbjct: 486 SESGEDDRDSLGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKH 545 Query: 204 LPSSKVNENSLGTLDE--SKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNK----- 256 + S E S S + + E + G S E+ KP K +E K Sbjct: 546 WRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLS 605 Query: 257 -------NSDGGSDPETQKEKSIQKQNSL---GSNEEK-----SKTLKKSNPYGEWQEIK 301 +S G+ P+ KE + K++ N+EK S+ LK + E+++ K Sbjct: 606 EKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSK 665 Query: 302 QEVESHEEVDLELPSTENE 320 Q+ + ++ +L STEN+ Sbjct: 666 QKSDKAILLENDL-STENK 683 Score = 30.4 bits (67), Expect = 2.7 Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 5/125 (4%) Query: 10 KKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSLDKAKEEEKASKEFAAME 69 KK DY + E H+ + K+ E + D+ K+ ++ KE Sbjct: 907 KKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDR-KDALESCKERRDGR 965 Query: 70 AAALKAYQEDLKRLGLESEILEPSITPVTSTIPPTSTSNQQKEKKEK----KKRKKDPSK 125 A +A++E+LK G ES + S + P + +EK++K K+RK+ Sbjct: 966 AKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKP 1025 Query: 126 GRWVE 130 R+ E Sbjct: 1026 ERYKE 1030 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 42.7 bits (99), Expect = 5e-04 Identities = 75/323 (23%), Positives = 126/323 (39%), Gaps = 79/323 (24%) Query: 30 HERGKNHKENVAKRISEI-KQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESE 88 HER K H+E K E +QK + A+E + ++ +E K +E R Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRERD--RLEQLERKRERERKMR------ 171 Query: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHY----YYDLI 144 +Q+E+KE+++R ++ K R S + Y D + Sbjct: 172 ----------------EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV 215 Query: 145 SGASQWEKP------EGFQ-GDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDF 197 AS W + E F+ GD +K + E E R D Sbjct: 216 K-ASHWSRSPPRPPRERFELGDGRKPVKE------------------EKMEER-----DL 251 Query: 198 IPHTSDLPSSKVNENSLGTLD-ESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNK 256 + D+ S+ +S + ES S + + E+E EEG S E+E+ + +E+ + Sbjct: 252 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE--EEEEEEE 309 Query: 257 NSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN-------PYGEW-QEIKQEVESHE 308 + GS+ E E+S ++ S EE S+ ++ N P + ++ + E+ E Sbjct: 310 EEETGSNSEEASEQSAEEV----SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 365 Query: 309 EVDLELPS----TENEYVSTSEA 327 EV P TE +YV S A Sbjct: 366 EVGEGTPQSSALTEGDYVPDSPA 388 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 42.7 bits (99), Expect = 5e-04 Identities = 75/323 (23%), Positives = 126/323 (39%), Gaps = 79/323 (24%) Query: 30 HERGKNHKENVAKRISEI-KQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESE 88 HER K H+E K E +QK + A+E + ++ +E K +E R Sbjct: 97 HERRKRHREEQDKARREWERQKRREMAREHSRRERD--RLEQLERKRERERKMR------ 148 Query: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHY----YYDLI 144 +Q+E+KE+++R ++ K R S + Y D + Sbjct: 149 ----------------EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV 192 Query: 145 SGASQWEKP------EGFQ-GDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDF 197 AS W + E F+ GD +K + E E R D Sbjct: 193 K-ASHWSRSPPRPPRERFELGDGRKPVKE------------------EKMEER-----DL 228 Query: 198 IPHTSDLPSSKVNENSLGTLD-ESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNK 256 + D+ S+ +S + ES S + + E+E EEG S E+E+ + +E+ + Sbjct: 229 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE--EEEEEEE 286 Query: 257 NSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN-------PYGEW-QEIKQEVESHE 308 + GS+ E E+S ++ S EE S+ ++ N P + ++ + E+ E Sbjct: 287 EEETGSNSEEASEQSAEEV----SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 342 Query: 309 EVDLELPS----TENEYVSTSEA 327 EV P TE +YV S A Sbjct: 343 EVGEGTPQSSALTEGDYVPDSPA 365 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 42.7 bits (99), Expect = 5e-04 Identities = 75/323 (23%), Positives = 126/323 (39%), Gaps = 79/323 (24%) Query: 30 HERGKNHKENVAKRISEI-KQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESE 88 HER K H+E K E +QK + A+E + ++ +E K +E R Sbjct: 86 HERRKRHREEQDKARREWERQKRREMAREHSRRERD--RLEQLERKRERERKMR------ 137 Query: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHY----YYDLI 144 +Q+E+KE+++R ++ K R S + Y D + Sbjct: 138 ----------------EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV 181 Query: 145 SGASQWEKP------EGFQ-GDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDF 197 AS W + E F+ GD +K + E E R D Sbjct: 182 K-ASHWSRSPPRPPRERFELGDGRKPVKE------------------EKMEER-----DL 217 Query: 198 IPHTSDLPSSKVNENSLGTLD-ESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNK 256 + D+ S+ +S + ES S + + E+E EEG S E+E+ + +E+ + Sbjct: 218 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE--EEEEEEE 275 Query: 257 NSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN-------PYGEW-QEIKQEVESHE 308 + GS+ E E+S ++ S EE S+ ++ N P + ++ + E+ E Sbjct: 276 EEETGSNSEEASEQSAEEV----SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 331 Query: 309 EVDLELPS----TENEYVSTSEA 327 EV P TE +YV S A Sbjct: 332 EVGEGTPQSSALTEGDYVPDSPA 354 >gi|58331179 KIAA1688 protein [Homo sapiens] Length = 1114 Score = 42.7 bits (99), Expect = 5e-04 Identities = 54/236 (22%), Positives = 95/236 (40%), Gaps = 40/236 (16%) Query: 128 WVEGITSEGYHYYY-DLISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTET 186 WVE I Y +L++G W+ P G + +K+T+ W YYYN T Sbjct: 30 WVEIIEPRTRERMYANLVTGECVWDPPAGVR--IKRTSENQWWELFDPNTSRFYYYNAST 87 Query: 187 GESRWEKPD--DFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTET 244 + W +P D IP + L + K N S ++S S G + EG S+ Sbjct: 88 QRTVWHRPQGCDIIP-LAKLQTLKQNTES------PRASAESSPGRGSSVSREGSTSSSL 140 Query: 245 EKPKIKFKEKNKNSDGGSDPETQKEKSIQ----KQNSLGSNEEKSKTLKKSNPYGEWQEI 300 E +P+T+K + + + + G+ +E S + S+P G + E Sbjct: 141 E----------------PEPDTEKAQELPARAGRPAAFGTVKEDSGS---SSPPGVFLEK 181 Query: 301 KQEVESHEEVDLELPSTENEYVSTSEADGGGEPKVVFK--EKTVTSLGVMADGVAP 354 E+ D +L + S+ + G + +++ K ++ + L +G AP Sbjct: 182 DYEIYRDYSADGQL---LHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAP 234 >gi|104526627 triadin [Homo sapiens] Length = 729 Score = 42.4 bits (98), Expect = 7e-04 Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 22/145 (15%) Query: 197 FIPHTSDLPSSKVNENSLGTLDESKSS---------DSHSDSDGEQEAEEGGVSTE-TEK 246 F SD+ SS+ E+ G D K + H D +QE E + T+ T K Sbjct: 106 FFSLLSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHK 165 Query: 247 PKIKFKEKNKNSDGGSDPETQKEKSIQKQN----SLGSNEEKSKTLKKSNPY-------G 295 K K KEK + + T KEK +K+ +L ++K+KT +KS G Sbjct: 166 EKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGG 225 Query: 296 EWQEIKQEVESHEEVDLELPSTENE 320 + +++KQ +EV + PS E Sbjct: 226 KQEKVKQTAAKVKEVQ-KTPSKPKE 249 Score = 40.8 bits (94), Expect = 0.002 Identities = 73/325 (22%), Positives = 124/325 (38%), Gaps = 35/325 (10%) Query: 37 KENVAKRISEIKQKSLDKAKEEEKASKEFAAM------EAAALKAYQEDL-----KRLGL 85 +E V + +++K+ +K +EK KE AA+ + A Y D+ + G Sbjct: 227 QEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQ 286 Query: 86 ESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKK--DPSKGRWVEGITSEGYHYYYDL 143 I P T S P S + ++KE ++KK KK +K + E I + Sbjct: 287 SPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAID 346 Query: 144 ISGASQWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDFIPHTSD 203 + + E QG +K A + ED E + + +K + H Sbjct: 347 VEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEP 406 Query: 204 LPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEE-GGVSTETEKPKIKFKEKNKNSDGGS 262 S K + S SD + E+ EE G VS + P K ++ K Sbjct: 407 AKSPK--------KEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKT----V 454 Query: 263 DPETQKEKSIQKQNSL-------GSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELP 315 + E +KEKS + + L G E+ +LK+ P E ++ ++ ++ +EV + P Sbjct: 455 EQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEP--ETKKDEKMSKAGKEVKPKPP 512 Query: 316 STENEYVSTSEADGGGEPKVVFKEK 340 + + E E K EK Sbjct: 513 QLQGKKEEKPEPQIKKEAKPAISEK 537 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 42.0 bits (97), Expect = 0.001 Identities = 29/150 (19%), Positives = 56/150 (37%) Query: 183 NTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVST 242 N+ + + D +SD +S + +S + D S SSDS + SD ++ S Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017 Query: 243 ETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQ 302 ++ + +S SD + S +S SN S S+ + + Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077 Query: 303 EVESHEEVDLELPSTENEYVSTSEADGGGE 332 +S E D S ++ +S++ + Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107 Score = 40.4 bits (93), Expect = 0.003 Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 2/146 (1%) Query: 183 NTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVST 242 ++++ +S D S S + +S + D S SSDS SD ++ S+ Sbjct: 568 DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627 Query: 243 ETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQ 302 ++E K+ +SD S + S NS SN S S+ + Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS--SNSSDSSDSSDSSDSSSSSDSSN 685 Query: 303 EVESHEEVDLELPSTENEYVSTSEAD 328 +S + D S ++ +S++D Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSD 711 Score = 40.4 bits (93), Expect = 0.003 Identities = 28/132 (21%), Positives = 50/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS + SD +E S ++ + +S Sbjct: 1114 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + + +S + D S NE Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1234 SSDSSDSSDSSD 1245 Score = 39.7 bits (91), Expect = 0.004 Identities = 28/135 (20%), Positives = 49/135 (36%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD S + +S + D S SSDS SD ++ S ++ + +S Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1199 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTEN 319 SD + S +S S+ S SN + + +S D S + Sbjct: 1200 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSS 1259 Query: 320 EYVSTSEADGGGEPK 334 + S S + + K Sbjct: 1260 DSTSDSNDESDSQSK 1274 Score = 39.3 bits (90), Expect = 0.006 Identities = 27/133 (20%), Positives = 51/133 (38%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD +S + NS + D S SSDS SD ++ S ++ + +S Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTEN 319 SD + S +S S+ S S+ + + S + D S + Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136 Query: 320 EYVSTSEADGGGE 332 + ++S++ E Sbjct: 1137 DSSNSSDSSDSSE 1149 Score = 38.9 bits (89), Expect = 0.008 Identities = 26/132 (19%), Positives = 51/132 (38%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD +S + +S + D S SSDS SD + ++ S ++ + +S Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + E +S + D S ++ Sbjct: 1111 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSD 1170 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1171 SSDSSDSSNSSD 1182 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/132 (19%), Positives = 49/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS SD ++ S ++ + + NS Sbjct: 1036 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSD 1095 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + + S + D S ++ Sbjct: 1096 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1156 SSDSSDSSDSSD 1167 Score = 38.5 bits (88), Expect = 0.010 Identities = 26/132 (19%), Positives = 50/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS SD ++ S ++ + + +S Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + + +S + D S ++ Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1221 Query: 321 YVSTSEADGGGE 332 +S++ E Sbjct: 1222 SSDSSDSSDSNE 1233 Score = 38.1 bits (87), Expect = 0.013 Identities = 26/127 (20%), Positives = 49/127 (38%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + NS + D S SSDS + SD ++ S ++ + +S Sbjct: 991 SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD 1050 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + + +S + D S ++ Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSD 1110 Query: 321 YVSTSEA 327 +S++ Sbjct: 1111 SSDSSDS 1117 Score = 38.1 bits (87), Expect = 0.013 Identities = 27/132 (20%), Positives = 48/132 (36%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS SD ++ S ++ + +S Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S SN S S+ + +S E D S ++ Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1162 SSDSSDSSDSSD 1173 Score = 38.1 bits (87), Expect = 0.013 Identities = 27/132 (20%), Positives = 48/132 (36%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + NS + D S SSDS SD ++ S ++ + +S Sbjct: 1045 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + ES + D S ++ Sbjct: 1105 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD 1164 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1165 SSDSSDSSDSSD 1176 Score = 38.1 bits (87), Expect = 0.013 Identities = 27/132 (20%), Positives = 49/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + NS + D S+SSDS SD ++ S ++ + +S Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + + ES + D S + Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1249 SSDSSDSSDSSD 1260 Score = 37.7 bits (86), Expect = 0.017 Identities = 25/127 (19%), Positives = 49/127 (38%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS SD ++ S ++ + +S Sbjct: 1009 SSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1068 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S ++S S+ S S+ + + +S + D S ++ Sbjct: 1069 SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1128 Query: 321 YVSTSEA 327 +S++ Sbjct: 1129 SSDSSDS 1135 Score = 37.4 bits (85), Expect = 0.022 Identities = 25/133 (18%), Positives = 49/133 (36%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD S + +S + D S SSDS SD +E S ++ + + ++ Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTEN 319 SD + S +S S+ S S+ + +S + D S + Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783 Query: 320 EYVSTSEADGGGE 332 + +S + + Sbjct: 784 DSNDSSNSSDSSD 796 Score = 37.4 bits (85), Expect = 0.022 Identities = 25/132 (18%), Positives = 51/132 (38%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + + S SSDS + SD ++ S ++ + NS Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1125 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ +S S+ + + +S + D S ++ Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1186 SSDSSDSSDSSD 1197 Score = 37.4 bits (85), Expect = 0.022 Identities = 30/133 (22%), Positives = 53/133 (39%), Gaps = 2/133 (1%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS SD ++ S ++ + +S Sbjct: 1159 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1218 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEV-ESHEEVDLELPS-TE 318 SD + S ++S S+ S S+ + + +S++E D + S Sbjct: 1219 SSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNG 1278 Query: 319 NEYVSTSEADGGG 331 N S S++D G Sbjct: 1279 NNNGSDSDSDSEG 1291 Score = 37.0 bits (84), Expect = 0.029 Identities = 25/140 (17%), Positives = 52/140 (37%) Query: 193 KPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFK 252 K D ++SD + + +S + + S SSDS SD ++ S ++ Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698 Query: 253 EKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDL 312 ++ +S SD ++ NS S+ S S+ + + S + D Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758 Query: 313 ELPSTENEYVSTSEADGGGE 332 S ++ +S++ + Sbjct: 759 SDSSNSSDSSDSSDSSDSSD 778 Score = 37.0 bits (84), Expect = 0.029 Identities = 25/131 (19%), Positives = 48/131 (36%) Query: 202 SDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGG 261 SD S + NS + D S SSDS S SD ++ S + + + +SD Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713 Query: 262 SDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEY 321 ++ S +S S+ S S+ + +S + + S ++ Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773 Query: 322 VSTSEADGGGE 332 +S++ + Sbjct: 774 SDSSDSSNSSD 784 Score = 37.0 bits (84), Expect = 0.029 Identities = 29/112 (25%), Positives = 44/112 (39%), Gaps = 8/112 (7%) Query: 183 NTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSH--SDSDGEQEAEEGGV 240 N+ + D ++SD +S + +S + D S SSDS SDSD ++ Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864 Query: 241 STETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN 292 S ++ + NS SD E S +S SN S + SN Sbjct: 865 SDSSD------SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910 Score = 37.0 bits (84), Expect = 0.029 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 1/92 (1%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + NS + D S SSDS S SD ++ S ++ + N NS Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDS-SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN 292 S+ + S +S SN S S+ Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969 Score = 37.0 bits (84), Expect = 0.029 Identities = 26/132 (19%), Positives = 48/132 (36%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS SD ++ S ++ + NS Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + +S + D S ++ Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1204 SSDSSDSSDSSD 1215 Score = 36.6 bits (83), Expect = 0.038 Identities = 24/122 (19%), Positives = 48/122 (39%) Query: 206 SSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPE 265 SS +++S D SKS SDSD + ++ + S ++ + NS SD Sbjct: 613 SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672 Query: 266 TQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVSTS 325 + S +S S+ S S+ + + S S++++ ++S Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732 Query: 326 EA 327 ++ Sbjct: 733 DS 734 Score = 36.6 bits (83), Expect = 0.038 Identities = 24/128 (18%), Positives = 53/128 (41%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +S+ +S + +S + D S SSDS + SD ++ S ++ + + +SD Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 718 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 + + + S +S SN S S+ + + S + D S ++ Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778 Query: 321 YVSTSEAD 328 ++S+++ Sbjct: 779 SSNSSDSN 786 Score = 36.6 bits (83), Expect = 0.038 Identities = 29/131 (22%), Positives = 53/131 (40%), Gaps = 3/131 (2%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD S + +S + D S SSDS SDSD ++ S ++ + +S Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDS-SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848 Query: 260 GGSDPET--QKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPST 317 GSD ++ + + S +S S+ S S+ E +S D + + Sbjct: 849 DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS 908 Query: 318 ENEYVSTSEAD 328 N S+ ++ Sbjct: 909 SNSSDSSDSSN 919 Score = 36.6 bits (83), Expect = 0.038 Identities = 25/133 (18%), Positives = 49/133 (36%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD S + +S + D S SSDS + SD ++ S ++ + +S Sbjct: 1002 NSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTEN 319 SD + S +S S S S+ + + +S + D S + Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121 Query: 320 EYVSTSEADGGGE 332 +S++ + Sbjct: 1122 NSSDSSDSSDSSD 1134 Score = 36.6 bits (83), Expect = 0.038 Identities = 27/150 (18%), Positives = 56/150 (37%) Query: 183 NTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVST 242 ++++ ES +SD S + +S + D S SSDS + SD ++ S Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137 Query: 243 ETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQ 302 + ++ +S SD + S +S S+ S S+ + + Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197 Query: 303 EVESHEEVDLELPSTENEYVSTSEADGGGE 332 +S + D S ++ +S++ + Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227 Score = 36.2 bits (82), Expect = 0.049 Identities = 25/133 (18%), Positives = 50/133 (37%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD S + +S + D S SSDS SD + S ++ + +S Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTEN 319 SD + S +S S+ S S+ + + +S + D S + Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175 Query: 320 EYVSTSEADGGGE 332 + ++S++ + Sbjct: 1176 DSSNSSDSSDSSD 1188 Score = 35.8 bits (81), Expect = 0.065 Identities = 26/133 (19%), Positives = 49/133 (36%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD +S + +S + D S SSDS SD ++ S ++ + +S Sbjct: 1023 NSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTEN 319 SD S +S S+ S S+ + +S + D S + Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142 Query: 320 EYVSTSEADGGGE 332 + +SE+ + Sbjct: 1143 DSSDSSESSDSSD 1155 Score = 35.8 bits (81), Expect = 0.065 Identities = 25/132 (18%), Positives = 49/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS SD ++ S ++ + +S Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + + +S + D S ++ Sbjct: 1168 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1227 Query: 321 YVSTSEADGGGE 332 ++E+ + Sbjct: 1228 SSDSNESSDSSD 1239 Score = 35.8 bits (81), Expect = 0.065 Identities = 26/127 (20%), Positives = 48/127 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD +S + +S + D S SSDS SD ++ S + + +S Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + E +S + D S ++ Sbjct: 1195 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254 Query: 321 YVSTSEA 327 +S++ Sbjct: 1255 SSDSSDS 1261 Score = 35.4 bits (80), Expect = 0.084 Identities = 25/132 (18%), Positives = 49/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD +S + +S + D S SSDS + SD ++ S ++ + +S Sbjct: 997 SSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + +S + D S ++ Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116 Query: 321 YVSTSEADGGGE 332 +S + + Sbjct: 1117 SSDSSNSSDSSD 1128 Score = 35.4 bits (80), Expect = 0.084 Identities = 25/132 (18%), Positives = 49/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD +S + NS + + S SSDS SD ++ S + + +S Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S SN S S+ + + +S + + S ++ Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1131 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1132 SSDSSDSSNSSD 1143 Score = 35.4 bits (80), Expect = 0.084 Identities = 24/132 (18%), Positives = 50/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S+SSDS S+ ++ S ++ + +S Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + + +S + D S ++ Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1183 SSDSSDSSDSSD 1194 Score = 34.7 bits (78), Expect = 0.14 Identities = 30/164 (18%), Positives = 60/164 (36%), Gaps = 5/164 (3%) Query: 174 SEDGFTYYYNTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDS-----HSD 228 S D ++++ ES + +S+ S + +S + D S SSDS SD Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970 Query: 229 SDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTL 288 S+ ++ S ++ + +S SD + S +S SN S Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030 Query: 289 KKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVSTSEADGGGE 332 S+ + + +S + D S ++ +S++ + Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1074 Score = 34.7 bits (78), Expect = 0.14 Identities = 24/132 (18%), Positives = 49/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + + S SSDS SD ++ S ++ + +S Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S ++S S+ S S+ + + S + D S ++ Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1195 SSDSSDSSDSSD 1206 Score = 34.3 bits (77), Expect = 0.19 Identities = 22/93 (23%), Positives = 35/93 (37%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD S + +S + D S SSDS SD ++ S ++ + +S Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN 292 SD S +S S+ S SN Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822 Score = 34.3 bits (77), Expect = 0.19 Identities = 26/110 (23%), Positives = 41/110 (37%), Gaps = 1/110 (0%) Query: 183 NTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVST 242 N+ + D +S+ S + +S + D S SSDS SDS E+ S+ Sbjct: 837 NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS-SDSSDSNESSNSSDSS 895 Query: 243 ETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN 292 ++ + NS SD + S +S SN S S+ Sbjct: 896 DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945 Score = 34.3 bits (77), Expect = 0.19 Identities = 29/129 (22%), Positives = 51/129 (39%), Gaps = 3/129 (2%) Query: 202 SDLPSSKVNENSLGTLDESKSSDS--HSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 SD SS +++S + D S SSDS SDS ++ E S+++ + +S Sbjct: 851 SDSDSSNRSDSS-NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTEN 319 SD S ++S S+ S S+ + + +S D S + Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969 Query: 320 EYVSTSEAD 328 + S+ +D Sbjct: 970 DSNSSDSSD 978 Score = 33.9 bits (76), Expect = 0.25 Identities = 29/141 (20%), Positives = 51/141 (36%), Gaps = 12/141 (8%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDS------------HSDSDGEQEAEEGGVSTETEKP 247 ++SD S + NS + D S SSDS SDSD ++ S ++ Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744 Query: 248 KIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESH 307 + +S SD + S +S S+ S S+ + + +S Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804 Query: 308 EEVDLELPSTENEYVSTSEAD 328 D S ++ S++ +D Sbjct: 805 NSSDSSDSSDSSDSDSSNSSD 825 Score = 33.9 bits (76), Expect = 0.25 Identities = 24/128 (18%), Positives = 46/128 (35%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S +++S + S SDS + SD + S ++ + +S Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + +S + D + N Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823 Query: 321 YVSTSEAD 328 S++ +D Sbjct: 824 SDSSNSSD 831 Score = 33.9 bits (76), Expect = 0.25 Identities = 26/128 (20%), Positives = 46/128 (35%), Gaps = 1/128 (0%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS SD ++ S + + NS Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 S+ + S +S SN S S+ + +S + D + + + Sbjct: 803 SSNSSDSSDSS-DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861 Query: 321 YVSTSEAD 328 S+ +D Sbjct: 862 SNSSDSSD 869 Score = 33.9 bits (76), Expect = 0.25 Identities = 24/133 (18%), Positives = 52/133 (39%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD S + +S + D S SSDS + SD ++ S ++ ++ +S Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTEN 319 S+ + S +S S+ S S+ + + +S + + S + Sbjct: 1089 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSS 1148 Query: 320 EYVSTSEADGGGE 332 E +S++ + Sbjct: 1149 ESSDSSDSSDSSD 1161 Score = 33.9 bits (76), Expect = 0.25 Identities = 24/132 (18%), Positives = 49/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + + S SSDS SD ++ S +E + +S Sbjct: 1039 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD 1098 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + + +S + + S ++ Sbjct: 1099 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSD 1158 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1159 SSDSSDSSDSSD 1170 Score = 33.5 bits (75), Expect = 0.32 Identities = 25/132 (18%), Positives = 47/132 (35%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + + S SSDS SD ++ S + + +S Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSD 1044 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + E +S D S ++ Sbjct: 1045 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1105 SSDSSDSSDSSD 1116 Score = 33.5 bits (75), Expect = 0.32 Identities = 26/130 (20%), Positives = 51/130 (39%), Gaps = 6/130 (4%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS + SD ++ S ++ + +S Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD------SSDSSDSSD 1206 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S +S S+ S S+ + + +S + D ++++ Sbjct: 1207 SSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSN 1266 Query: 321 YVSTSEADGG 330 S S++ G Sbjct: 1267 DESDSQSKSG 1276 Score = 33.1 bits (74), Expect = 0.42 Identities = 22/149 (14%), Positives = 57/149 (38%) Query: 184 TETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTE 243 +++G+ + + D +S+ S + +S + S S SDSD ++ + Sbjct: 540 SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSS 599 Query: 244 TEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQE 303 + + +SD +++ + S + +S S+ + + S+ + + Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659 Query: 304 VESHEEVDLELPSTENEYVSTSEADGGGE 332 S D S ++ S+S++ + Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688 Score = 33.1 bits (74), Expect = 0.42 Identities = 25/132 (18%), Positives = 46/132 (34%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS S+ + S ++ + +S Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD S +S S+ S S+ E + S + D S ++ Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107 Query: 321 YVSTSEADGGGE 332 +S++ + Sbjct: 1108 SSDSSDSSDSSD 1119 Score = 33.1 bits (74), Expect = 0.42 Identities = 24/133 (18%), Positives = 49/133 (36%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD S + +S + + S SSDS SD ++ S ++ + NS Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTEN 319 SD + S +S S+ S S+ + + +S + + S + Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241 Query: 320 EYVSTSEADGGGE 332 + +S + + Sbjct: 1242 DSSDSSNSSDSSD 1254 Score = 32.7 bits (73), Expect = 0.55 Identities = 22/93 (23%), Positives = 38/93 (40%), Gaps = 1/93 (1%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSD 259 ++SD S + NS + D S SSDS SDS ++ + S+++ N + Sbjct: 751 NSSDSSDSSDSSNSSDSSDSSDSSDS-SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809 Query: 260 GGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN 292 S + + S +S S+ S S+ Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS 842 Score = 32.3 bits (72), Expect = 0.71 Identities = 30/142 (21%), Positives = 55/142 (38%), Gaps = 9/142 (6%) Query: 195 DDFIPHTSDLPSSKVNENSLGTLDESKSSD--------SHSDSDGEQEAEEGGVSTETEK 246 DD TSD +S N N D++ SD S SDS + + S++++ Sbjct: 512 DDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571 Query: 247 PKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVES 306 + +SD S + + S +S S+ S S+ + + + ES Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631 Query: 307 HEEVDLELPSTENEYVSTSEAD 328 + D + S ++ S+ +D Sbjct: 632 -DSSDSDSKSDSSDSNSSDSSD 652 Score = 32.3 bits (72), Expect = 0.71 Identities = 17/71 (23%), Positives = 32/71 (45%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + S + D S SSDS + SD ++ ++++ + ++ Sbjct: 1222 SSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNN 1281 Query: 261 GSDPETQKEKS 271 GSD ++ E S Sbjct: 1282 GSDSDSDSEGS 1292 Score = 31.6 bits (70), Expect = 1.2 Identities = 28/136 (20%), Positives = 52/136 (38%), Gaps = 12/136 (8%) Query: 200 HTSDLPSSKVNENSLGTLDESKSSDSHSDSDG--------EQEAEEGGVSTETEKPKIKF 251 ++SD S + +S + + S S+DS + SD + + S+++ Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822 Query: 252 KEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVD 311 + NS SD + S +S GS+ + S SN + +S D Sbjct: 823 SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS----SDSSDSSDSSNSSD 878 Query: 312 LELPSTENEYVSTSEA 327 S NE ++S++ Sbjct: 879 SSDSSDSNESSNSSDS 894 Score = 30.8 bits (68), Expect = 2.1 Identities = 24/111 (21%), Positives = 44/111 (39%), Gaps = 12/111 (10%) Query: 222 SSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSN 281 +SD +G E E+ G + ++ K+ + NS G + KE +S+G N Sbjct: 241 NSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDD--HDSSIGQN 298 Query: 282 EEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENEYVSTSEADGGGE 332 + E+ + + + + H EVD + S E + D G + Sbjct: 299 SDSK----------EYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQ 339 Score = 30.8 bits (68), Expect = 2.1 Identities = 20/132 (15%), Positives = 49/132 (37%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S ++++ + +S SDS SD + + + + +SD Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLELPSTENE 320 SD + S + S++ S ++ + +S + D S+ ++ Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682 Query: 321 YVSTSEADGGGE 332 ++S++ + Sbjct: 683 SSNSSDSSDSSD 694 Score = 30.4 bits (67), Expect = 2.7 Identities = 58/318 (18%), Positives = 116/318 (36%), Gaps = 27/318 (8%) Query: 20 IADNRPSVEFHE-RGKNHKENVAKRISEIKQKSLDKAKEEEKASKEFAAMEAAALKAYQE 78 I N S E+++ GK N K + E+ S+ E Sbjct: 295 IGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRI------------E 342 Query: 79 DLKRLG-LESEILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSK--GRWVEGITSE 135 D ++L ES+ +E IT + T + ++ E K ++ +K G+ EG + Sbjct: 343 DTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDK 402 Query: 136 GYHYYYDLISGASQWEKPEGFQGDLKKTAVKT-----VWVEGLSEDGFTYYYNTETGESR 190 G H +I G K +G +++ K+ V D + Y++ + + Sbjct: 403 GQH---GMILGKGN-VKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDK 458 Query: 191 WEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIK 250 + DD P++SD + + NS + S D+ +SD ++ G S E Sbjct: 459 SMQGDD--PNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD 516 Query: 251 FKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEV 310 NSD + + + + + G ++ S+ + + S Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576 Query: 311 DLELPSTENEYVSTSEAD 328 + S++++ +S++D Sbjct: 577 SSDSDSSDSDSSDSSDSD 594 Score = 30.4 bits (67), Expect = 2.7 Identities = 19/92 (20%), Positives = 36/92 (39%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD S + +S + D S SSDS ++ ++ S + + +S Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN 292 S+ E+ + N+ GS+ + SN Sbjct: 1264 DSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295 Score = 30.0 bits (66), Expect = 3.5 Identities = 19/92 (20%), Positives = 35/92 (38%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +S S + +S +S SSDS +SD + S ++ + +S Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN 292 SD + S ++S S+ S + S+ Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSD 717 Score = 30.0 bits (66), Expect = 3.5 Identities = 21/92 (22%), Positives = 37/92 (40%), Gaps = 1/92 (1%) Query: 201 TSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNKNSDG 260 +SD +S + +S + + S SSDS SDS +++ S ++ + S Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDS-SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928 Query: 261 GSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN 292 SD + S +S S+ S S+ Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960 Score = 28.9 bits (63), Expect = 7.9 Identities = 19/105 (18%), Positives = 41/105 (39%) Query: 183 NTETGESRWEKPDDFIPHTSDLPSSKVNENSLGTLDESKSSDSHSDSDGEQEAEEGGVST 242 + + +S K D +SD +S + +S + +S S SDS ++ + Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS 595 Query: 243 ETEKPKIKFKEKNKNSDGGSDPETQKEKSIQKQNSLGSNEEKSKT 287 + + +SD ++ KS ++ S++ SK+ Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 41.6 bits (96), Expect = 0.001 Identities = 75/323 (23%), Positives = 130/323 (40%), Gaps = 70/323 (21%) Query: 30 HERGKNHKENVAKRISEI-KQKSLDKAKEEEKASKEFAAMEAAALKAYQEDLKRLGLESE 88 HER K H+E K E +QK + A+E + + + L +++ L++L + E Sbjct: 120 HERRKRHREEQDKARREWERQKRREMAREHSRRER---GNDGVCL--FRDRLEQLERKRE 174 Query: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHY----YYDLI 144 +Q+E+KE+++R ++ K R S + Y D + Sbjct: 175 RERKM----------REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKV 224 Query: 145 SGASQWEKP------EGFQ-GDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKPDDF 197 AS W + E F+ GD +K + E E R D Sbjct: 225 K-ASHWSRSPPRPPRERFELGDGRKPVKE------------------EKMEER-----DL 260 Query: 198 IPHTSDLPSSKVNENSLGTLD-ESKSSDSHSDSDGEQEAEEGGVSTETEKPKIKFKEKNK 256 + D+ S+ +S + ES S + + E+E EEG S E+E+ + +E+ + Sbjct: 261 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE--EEEEEEE 318 Query: 257 NSDGGSDPETQKEKSIQKQNSLGSNEEKSKTLKKSN-------PYGEW-QEIKQEVESHE 308 + GS+ E E+S ++ S EE S+ ++ N P + ++ + E+ E Sbjct: 319 EEETGSNSEEASEQSAEEV----SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE 374 Query: 309 EVDLELPS----TENEYVSTSEA 327 EV P TE +YV S A Sbjct: 375 EVGEGTPQSSALTEGDYVPDSPA 397 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.303 0.124 0.348 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,978,656 Number of Sequences: 37866 Number of extensions: 783321 Number of successful extensions: 6307 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 140 Number of HSP's successfully gapped in prelim test: 439 Number of HSP's that attempted gapping in prelim test: 4443 Number of HSP's gapped (non-prelim): 1880 length of query: 376 length of database: 18,247,518 effective HSP length: 104 effective length of query: 272 effective length of database: 14,309,454 effective search space: 3892171488 effective search space used: 3892171488 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.