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Search of human proteins with 5902076
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5902076 splicing factor, arginine/serine-rich 1 isoform 1
[Homo sapiens]
(248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5902076 splicing factor, arginine/serine-rich 1 isoform 1 [Ho... 516 e-147
gi|118582269 splicing factor, arginine/serine-rich 1 isoform 2 [... 392 e-109
gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens] 297 5e-81
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 172 3e-43
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 170 1e-42
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] 168 4e-42
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] 168 4e-42
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 89 3e-18
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 84 1e-16
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 77 1e-14
gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens] 75 4e-14
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso... 65 5e-11
gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sa... 62 4e-10
gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sap... 62 4e-10
gi|13899354 RNA binding motif protein 4B [Homo sapiens] 62 5e-10
gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] 61 1e-09
gi|93277122 RNA binding motif protein 4 [Homo sapiens] 60 1e-09
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 60 2e-09
gi|20911035 peptidylprolyl isomerase-like 4 [Homo sapiens] 58 7e-09
gi|4502847 cold inducible RNA binding protein [Homo sapiens] 57 1e-08
gi|9558733 transformer-2 alpha [Homo sapiens] 56 3e-08
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 55 7e-08
gi|239752336 PREDICTED: similar to RNA binding motif protein, X-... 54 2e-07
gi|239746849 PREDICTED: hypothetical protein XP_002343863 [Homo ... 54 2e-07
gi|50962882 G patch domain containing 8 [Homo sapiens] 53 2e-07
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 52 5e-07
gi|9945320 cyclin L1 [Homo sapiens] 52 5e-07
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 52 6e-07
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 52 6e-07
gi|5031703 Ras-GTPase-activating protein SH3-domain-binding prot... 52 6e-07
>gi|5902076 splicing factor, arginine/serine-rich 1 isoform 1 [Homo
sapiens]
Length = 248
Score = 516 bits (1328), Expect = e-147
Identities = 248/248 (100%), Positives = 248/248 (100%)
Query: 1 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE 60
MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE
Sbjct: 1 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE 60
Query: 61 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE 120
FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE
Sbjct: 61 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE 120
Query: 121 NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF 180
NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF
Sbjct: 121 NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF 180
Query: 181 RSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPR 240
RSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPR
Sbjct: 181 RSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPR 240
Query: 241 HSRSRSRT 248
HSRSRSRT
Sbjct: 241 HSRSRSRT 248
>gi|118582269 splicing factor, arginine/serine-rich 1 isoform 2
[Homo sapiens]
Length = 201
Score = 392 bits (1006), Expect = e-109
Identities = 186/192 (96%), Positives = 187/192 (97%), Gaps = 2/192 (1%)
Query: 1 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE 60
MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE
Sbjct: 1 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE 60
Query: 61 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE 120
FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE
Sbjct: 61 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE 120
Query: 121 NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF 180
NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF
Sbjct: 121 NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF 180
Query: 181 RSHEGETAYIRV 192
RSH E Y R+
Sbjct: 181 RSH--EVGYTRI 190
>gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens]
Length = 221
Score = 297 bits (761), Expect = 5e-81
Identities = 159/238 (66%), Positives = 179/238 (75%), Gaps = 25/238 (10%)
Query: 1 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE 60
MSG RG G D RIYVGNLP D+R KD+ED+FYKYG IR+I+LKNR G PFAFV
Sbjct: 1 MSGWADERG--GEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVR 58
Query: 61 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRG-RYGPPSRRS 119
FEDPRDAEDA+YGR+GYDY RLRVEFPR+ GG GG PRG R GPP+RRS
Sbjct: 59 FEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTY---------GGRGGWPRGGRNGPPTRRS 109
Query: 120 ENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTK 179
+ RV+VSGLPPSGSWQDLKDHMREAGDVCYADV +DG G+VE++RKEDM YA+RKLD+TK
Sbjct: 110 DFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTK 169
Query: 180 FRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRY 237
FRSHEGET+YIRV + RS SYG SRSRS SR R SP +SRGSP Y
Sbjct: 170 FRSHEGETSYIRVYPE--RSTSYGYSRSRSGSRGRD-----------SPYQSRGSPHY 214
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 172 bits (435), Expect = 3e-43
Identities = 112/241 (46%), Positives = 140/241 (58%), Gaps = 20/241 (8%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDG 76
R+Y+G L R +D+E F YG I ++DLKN G FVEF+D RDA+DAVY +G
Sbjct: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYG-----FVEFDDLRDADDAVYELNG 57
Query: 77 YDYDGYRLRVEFPRSGRGTGRGGGGGGGGG---APRGRYGPPSRRSENRVVVSGLPPSGS 133
D G R+ VE R R G G G G G + R +YGPP+R +E R++V L S
Sbjct: 58 KDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTR-TEYRLIVENLSSRCS 116
Query: 134 WQDLKDHMREAGDVCYADVY--RDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIR 191
WQDLKD+MR+AG+V YAD + R GV+EFV DM A+ KLD T+ + IR
Sbjct: 117 WQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRK-----IR 171
Query: 192 VKVDGP---RSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRH-SRSRSR 247
+ D P R SY RSRS SRSRSRSR SRSRS S + S R R SRSRS+
Sbjct: 172 LVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
Query: 248 T 248
+
Sbjct: 232 S 232
Score = 48.9 bits (115), Expect = 4e-06
Identities = 73/283 (25%), Positives = 104/283 (36%), Gaps = 50/283 (17%)
Query: 9 GPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDL-KNRRGGPPFAFVEFEDPRDA 67
GP + R+ V NL +D++D + G + D K R+ FV + D + A
Sbjct: 97 GPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRA 156
Query: 68 EDAVYGRDGYDYDGYRLRVEFPRSG------------------------RGTGRGGGGGG 103
+ + DG + +G ++R+ + G + R G
Sbjct: 157 LEKL---DGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS 213
Query: 104 GGGAPRGRYGPPSR-------RSENRV---VVSGLPPSGSWQDLKDHMREAGDVCYADVY 153
R R SR RS++R PS + H D
Sbjct: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA 273
Query: 154 RDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRS-------- 205
+ + V K R +K RS E RV+ + S S GRS
Sbjct: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQER---RVEEEKRGSVSRGRSQEKSLRQS 330
Query: 206 RSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT 248
RSRSRS+ SRSRS SRS+S R+ R R R SRSRSR+
Sbjct: 331 RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESR-SRSRSRS 372
Score = 48.5 bits (114), Expect = 5e-06
Identities = 48/155 (30%), Positives = 66/155 (42%), Gaps = 33/155 (21%)
Query: 90 RSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCY 149
+S R RG G+ + + + RS++R PS S ++H +
Sbjct: 373 KSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSR------SPSRSVSKEREHAKSESS--- 423
Query: 150 ADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRS 209
R+G G E T + R N+K + P PS RSRS+S
Sbjct: 424 ---QREGRGESENAGTNQETRS-RSRSNSKSK---------------PNLPSESRSRSKS 464
Query: 210 RSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRS 244
S++RSRS+S SRS S SP RSR S HSRS
Sbjct: 465 ASKTRSRSKSRSRSASRSPSRSR-----SRSHSRS 494
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/48 (50%), Positives = 27/48 (56%)
Query: 198 RSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSR 245
RS S G SRSRSRSRS+S+ + R RS RSR R SR R
Sbjct: 333 RSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR 380
Score = 39.7 bits (91), Expect = 0.002
Identities = 30/61 (49%), Positives = 32/61 (52%), Gaps = 11/61 (18%)
Query: 198 RSPSYGRSRSRSRS----------RSRSRSRSNSRSRSYSPR-RSRGSPRYSPRHSRSRS 246
RS RSRSRSRS RSR SRS SRSRS S R R RGS R S S +
Sbjct: 335 RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKK 394
Query: 247 R 247
+
Sbjct: 395 K 395
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 170 bits (430), Expect = 1e-42
Identities = 111/243 (45%), Positives = 141/243 (58%), Gaps = 18/243 (7%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDG 76
R+Y+G L ++R KDI+ F YG + ++DLKN G FVEFED RDA+DAVY +G
Sbjct: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYG-----FVEFEDSRDADDAVYELNG 57
Query: 77 YDYDGYRLRVEFPRSGR----GTGRGGGGGGGGGAPR-----GRYGPPSRRSENRVVVSG 127
+ G R+ VE R R G G GGGG + R +YGPP R +E R++V
Sbjct: 58 KELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVR-TEYRLIVEN 116
Query: 128 LPPSGSWQDLKDHMREAGDVCYADVYRDGT--GVVEFVRKEDMTYAVRKLDNTKFRSHEG 185
L SWQDLKD MR+AG+V YAD +++ T GV+EF DM A+ KLD T+
Sbjct: 117 LSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNI 176
Query: 186 ETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSR 245
+ + RS S RSRSRSR RSRSRSR +SRSRS S +SR R S RSR
Sbjct: 177 RLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSR-SRSKGRSR 235
Query: 246 SRT 248
SR+
Sbjct: 236 SRS 238
Score = 48.1 bits (113), Expect = 7e-06
Identities = 67/261 (25%), Positives = 97/261 (37%), Gaps = 48/261 (18%)
Query: 9 GPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAE 68
GP + R+ V NL +D++D + G + D R +EF D +
Sbjct: 103 GPPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNE--GVIEFRSYSDMK 160
Query: 69 DAVYGRDGYDYDGYRLRV--EFPRSGRGTGRGGGGGGGGGAPRGRY-GPPSRRSENRVVV 125
A+ DG + +G +R+ + PR+ G R R S RS +R +
Sbjct: 161 RALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSIS 220
Query: 126 SGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEG 185
S S + R G RK R +K +S G
Sbjct: 221 KSRSRSRSRSKGRSRSRSKG------------------RKS------RSKSKSKPKSDRG 256
Query: 186 ETAYIRVKVDGPRSPSYGRSRSRS---------RSRSRSRSRSNSRS---------RSYS 227
++ R + S RSRSRS +S+SRSRS+S S S RS S
Sbjct: 257 SHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVS 316
Query: 228 PRRSRGSPRYSPRHSRSRSRT 248
P R + R S SRS+SR+
Sbjct: 317 PPPKRATSR-SRSRSRSKSRS 336
>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 168 bits (426), Expect = 4e-42
Identities = 110/242 (45%), Positives = 137/242 (56%), Gaps = 25/242 (10%)
Query: 16 CRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRD 75
CR+++G L P R KD+E F YG IRDIDLK RG F FVEFEDPRDA+DAVY D
Sbjct: 4 CRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--RG---FGFVEFEDPRDADDAVYELD 58
Query: 76 GYDYDGYRLRVEFPRS----GRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPS 131
G + R+ +E R+ GRG GR R P R+ENR++V L
Sbjct: 59 GKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSR 118
Query: 132 GSWQDLKDHMREAGDVCYADVYRD--GTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAY 189
SWQDLKD MR+AG+V +AD +R GVVEF D+ A+ KL + + +
Sbjct: 119 VSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKL-- 176
Query: 190 IRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSR---SYSPRRSRGSPRYSPRHSRSRS 246
++G + S RSRSRSR+RS SRSRS SRSR SYS RSR R SRS+S
Sbjct: 177 ----IEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR-----SRSKS 227
Query: 247 RT 248
R+
Sbjct: 228 RS 229
>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 168 bits (426), Expect = 4e-42
Identities = 110/242 (45%), Positives = 137/242 (56%), Gaps = 25/242 (10%)
Query: 16 CRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRD 75
CR+++G L P R KD+E F YG IRDIDLK RG F FVEFEDPRDA+DAVY D
Sbjct: 4 CRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--RG---FGFVEFEDPRDADDAVYELD 58
Query: 76 GYDYDGYRLRVEFPRS----GRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPS 131
G + R+ +E R+ GRG GR R P R+ENR++V L
Sbjct: 59 GKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSR 118
Query: 132 GSWQDLKDHMREAGDVCYADVYRD--GTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAY 189
SWQDLKD MR+AG+V +AD +R GVVEF D+ A+ KL + + +
Sbjct: 119 VSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKL-- 176
Query: 190 IRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSR---SYSPRRSRGSPRYSPRHSRSRS 246
++G + S RSRSRSR+RS SRSRS SRSR SYS RSR R SRS+S
Sbjct: 177 ----IEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR-----SRSKS 227
Query: 247 RT 248
R+
Sbjct: 228 RS 229
>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
Length = 238
Score = 89.4 bits (220), Expect = 3e-18
Identities = 87/250 (34%), Positives = 107/250 (42%), Gaps = 73/250 (29%)
Query: 15 DCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGR 74
+ ++YVGNL ++E F YG +R + + R P FAFVEFEDPRDAEDAV G
Sbjct: 10 ETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIA--RNPPGFAFVEFEDPRDAEDAVRGL 67
Query: 75 DGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSW 134
DG G R+RVE G P R +R PP+
Sbjct: 68 DGKVICGSRVRVELST----------------------GMPRRSRFDR------PPARRP 99
Query: 135 QDLKDHMREAGDVCY--ADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRV 192
D D E G+ + D +R Y+ R+ ++ RSH
Sbjct: 100 FDPNDRCYECGEKGHYAYDCHR---------------YSRRRRSRSRSRSHSRS------ 138
Query: 193 KVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGS------------PRY--S 238
R Y RSRSRSR R RSRS S RSRS S RRSR + RY S
Sbjct: 139 -----RGRRYSRSRSRSRGR-RSRSASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQS 192
Query: 239 PRHSRSRSRT 248
P SRSRSR+
Sbjct: 193 PSRSRSRSRS 202
Score = 32.3 bits (72), Expect = 0.39
Identities = 18/31 (58%), Positives = 19/31 (61%)
Query: 200 PSYGRSRSRSRSRSRSRSRSNSRSRSYSPRR 230
P RS+SRS S RSRS S S RS SP R
Sbjct: 206 PRSSRSKSRSPSPKRSRSPSGSPRRSASPER 236
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 84.0 bits (206), Expect = 1e-16
Identities = 85/259 (32%), Positives = 109/259 (42%), Gaps = 39/259 (15%)
Query: 20 VGNLPPDIRTKDIEDVFYKYGAIRDIDLKNR---RGGPPFAFVEFEDPRDAEDAVYGRDG 76
V NL + VF KYG + D+ + + FAFV F D RDA+DA DG
Sbjct: 18 VDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMDG 77
Query: 77 YDYDGYRLRVE--------FPRSGRGTGRGGGGGGGGG-----------APRGRY----- 112
+ DG LRV+ PRS +G RG GGG G +PR R+
Sbjct: 78 AELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSR 137
Query: 113 GPPSRRSENRVVVSGLPPSGSWQDLKDHMRE--AGDVCYADVYRDGTGVVEFVRKEDMTY 170
GP RS +R G S S + R + YR+ R Y
Sbjct: 138 GPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRES-------RYGGSHY 190
Query: 171 AVRKLDNTKF-RSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPR 229
+ N+++ R H + RS S +S S RS+S S SRS SRSRS S
Sbjct: 191 SSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMT 250
Query: 230 RSRGSPRYSPRHSRSRSRT 248
RS PR S R S+SRSR+
Sbjct: 251 RS--PPRVSKRKSKSRSRS 267
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 77.0 bits (188), Expect = 1e-14
Identities = 78/238 (32%), Positives = 93/238 (39%), Gaps = 58/238 (24%)
Query: 20 VGNLPPDIRTKDIEDVFYKYGAIRDIDL------KNRRGGPPFAFVEFEDPRDAEDAVYG 73
V NL + VF KYG + D+ + K RG FAFV F D RDAEDA+
Sbjct: 18 VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRG---FAFVRFHDKRDAEDAMDA 74
Query: 74 RDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGS 133
DG DG LRV+ R GR + R GPP RR
Sbjct: 75 MDGAVLDGRELRVQMARYGRPP----------DSHHSRRGPPPRR--------------- 109
Query: 134 WQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVK 193
G G R R ++ RS + Y R K
Sbjct: 110 --------------------YGGGGYGRRSRSPRRRRRSRSRSRSRSRS-RSRSRYSRSK 148
Query: 194 VDG---PRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT 248
RS S +SRS RS+S+S S S SRSRS S RSR P S R S+SRSR+
Sbjct: 149 SRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRS 206
>gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens]
Length = 164
Score = 75.5 bits (184), Expect = 4e-14
Identities = 47/112 (41%), Positives = 58/112 (51%), Gaps = 6/112 (5%)
Query: 15 DCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGR 74
DC++YVGNL + ++E F YG +R + + R P FAFVEFEDPRDA DAV
Sbjct: 9 DCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVA--RNPPGFAFVEFEDPRDAADAVREL 66
Query: 75 DGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRY----GPPSRRSENR 122
DG G R+RVE + + G G PR Y PP RRS R
Sbjct: 67 DGRTLCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRR 118
Score = 45.8 bits (107), Expect = 3e-05
Identities = 27/50 (54%), Positives = 31/50 (62%), Gaps = 5/50 (10%)
Query: 197 PRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRS 246
PR S+ RSRSRS SR R R RS SR R++ P RS +S SRSRS
Sbjct: 116 PRRRSFSRSRSRSLSRDRRRERSLSRERNHKPSRS-----FSRSRSRSRS 160
Score = 37.4 bits (85), Expect = 0.012
Identities = 50/153 (32%), Positives = 62/153 (40%), Gaps = 33/153 (21%)
Query: 122 RVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRD--GTGVVEFVRKEDMTYAVRKLDN-- 177
+V V L +G+ +L+ G + V R+ G VEF D AVR+LD
Sbjct: 11 KVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRT 70
Query: 178 -----TKFRSHEGETAYIRVKVDGP--------------RSPSYGRSRSRSRSRSRSRSR 218
+ GE R + GP RSP R R RS SRSRSR
Sbjct: 71 LCGCRVRVELSNGEK---RSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSR 127
Query: 219 SNSRSRSYSPRRSRGSPR---YSPRHSRSRSRT 248
S SR R RR R R + P S SRSR+
Sbjct: 128 SLSRDR----RRERSLSRERNHKPSRSFSRSRS 156
>gi|16905517 FUS interacting protein (serine-arginine rich) 1
isoform 2 [Homo sapiens]
Length = 262
Score = 65.1 bits (157), Expect = 5e-11
Identities = 70/243 (28%), Positives = 101/243 (41%), Gaps = 45/243 (18%)
Query: 18 IYVGNLPPDIRTKDIEDVFYKYGAIRDI----DLKNRRGGPPFAFVEFEDPRDAEDAVYG 73
++V N+ D R++D+ F +YG I D+ D RR FA+V+FED RDAEDA++
Sbjct: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRG-FAYVQFEDVRDAEDALHN 70
Query: 74 RDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGS 133
D G ++ ++F + R T + E R V S S
Sbjct: 71 LDRKWICGRQIEIQFAQGDRKTPN-----------------QMKAKEGRNVYS----SSR 109
Query: 134 WQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVK 193
+ D + R R + R Y R+ + + G R
Sbjct: 110 YDDYDRYRRS----------RSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSH 159
Query: 194 VDGPRSPSYGRSRSRSRSRSRSRSRS--------NSRSRSYSPRRSRGSPRY-SPRHSRS 244
D R RS SRS+S SRSRS+S SRSRS S ++RG+ + S H +S
Sbjct: 160 SDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKS 219
Query: 245 RSR 247
SR
Sbjct: 220 GSR 222
Score = 37.4 bits (85), Expect = 0.012
Identities = 18/28 (64%), Positives = 24/28 (85%)
Query: 206 RSRSRSRSRSRSRSNSRSRSYSPRRSRG 233
RS+S+SRS+SRSRS SRSRS++ +S G
Sbjct: 234 RSKSQSRSQSRSRSKSRSRSWTSPKSSG 261
Score = 36.2 bits (82), Expect = 0.027
Identities = 18/34 (52%), Positives = 25/34 (73%)
Query: 193 KVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSY 226
K + PRS S RS+SRSRS+SRSRS ++ +S +
Sbjct: 229 KKEPPRSKSQSRSQSRSRSKSRSRSWTSPKSSGH 262
>gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo
sapiens]
Length = 390
Score = 62.4 bits (150), Expect = 4e-10
Identities = 44/122 (36%), Positives = 56/122 (45%), Gaps = 26/122 (21%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAI------RDIDLKNRRGGPPFAFVEFEDPRDAEDA 70
++++G L + K +E VF KYG I +D + RG FAFV FE P DA+DA
Sbjct: 9 KLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRG---FAFVTFESPADAKDA 65
Query: 71 VYGRDGYDYDGYRLRVEF---------------PRSGRGTGRGGGGGGGGGAPRGRYGPP 115
+G DG ++VE P RG RG G G GG G GPP
Sbjct: 66 ARDMNGKSLDGKAIKVEQATKPSFERGRHGPPPPPRSRGPPRGFGAGRGGSG--GTRGPP 123
Query: 116 SR 117
SR
Sbjct: 124 SR 125
>gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo
sapiens]
Length = 390
Score = 62.4 bits (150), Expect = 4e-10
Identities = 44/122 (36%), Positives = 56/122 (45%), Gaps = 26/122 (21%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAI------RDIDLKNRRGGPPFAFVEFEDPRDAEDA 70
++++G L + K +E VF KYG I +D + RG FAFV FE P DA+DA
Sbjct: 9 KLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRG---FAFVTFESPADAKDA 65
Query: 71 VYGRDGYDYDGYRLRVEF---------------PRSGRGTGRGGGGGGGGGAPRGRYGPP 115
+G DG ++VE P RG RG G G GG G GPP
Sbjct: 66 ARDMNGKSLDGKAIKVEQATKPSFERGRHGPPPPPRSRGPPRGFGAGRGGSG--GTRGPP 123
Query: 116 SR 117
SR
Sbjct: 124 SR 125
>gi|13899354 RNA binding motif protein 4B [Homo sapiens]
Length = 359
Score = 62.0 bits (149), Expect = 5e-10
Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 32/166 (19%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDID-LKNRRGGPPFAFVEFEDPRDAEDAVYGRD 75
++++GNLP + ++I +F +YG + + D +KN + FV ED AEDA+
Sbjct: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN------YGFVHIEDKTAAEDAIRNLH 56
Query: 76 GYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQ 135
Y G + VE ++ ++ ++ V + P+ + Q
Sbjct: 57 HYKLHGVNINVEASKN------------------------KSKASTKLHVGNISPTCTNQ 92
Query: 136 DLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFR 181
+L+ E G V D+ +D V R ED A+R LDNT+F+
Sbjct: 93 ELRAKFEEYGPVIECDIVKD-YAFVHMERAEDAVEAIRGLDNTEFQ 137
>gi|56699409 RNA binding motif protein, X-linked [Homo sapiens]
Length = 391
Score = 60.8 bits (146), Expect = 1e-09
Identities = 44/122 (36%), Positives = 56/122 (45%), Gaps = 26/122 (21%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAI------RDIDLKNRRGGPPFAFVEFEDPRDAEDA 70
++++G L + K +E VF KYG I +D + RG FAFV FE P DA+DA
Sbjct: 9 KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRG---FAFVTFESPADAKDA 65
Query: 71 VYGRDGYDYDGYRLRVEF---------------PRSGRGTGRGGGGGGGGGAPRGRYGPP 115
+G DG ++VE P RG RG GG GG G GPP
Sbjct: 66 ARDMNGKSLDGKAIKVEQATKPSFESGRRGPPPPPRSRGPPRGLRGGRGGSG--GTRGPP 123
Query: 116 SR 117
SR
Sbjct: 124 SR 125
>gi|93277122 RNA binding motif protein 4 [Homo sapiens]
Length = 364
Score = 60.5 bits (145), Expect = 1e-09
Identities = 42/166 (25%), Positives = 74/166 (44%), Gaps = 32/166 (19%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDID-LKNRRGGPPFAFVEFEDPRDAEDAVYGRD 75
++++GNLP + ++I +F +YG + + D +KN + FV ED AEDA+
Sbjct: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN------YGFVHIEDKTAAEDAIRNLH 56
Query: 76 GYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQ 135
Y G + VE ++ ++ ++ V + P+ + +
Sbjct: 57 HYKLHGVNINVEASKN------------------------KSKTSTKLHVGNISPTCTNK 92
Query: 136 DLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFR 181
+L+ E G V D+ +D V R ED A+R LDNT+F+
Sbjct: 93 ELRAKFEEYGPVIECDIVKD-YAFVHMERAEDAVEAIRGLDNTEFQ 137
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 60.1 bits (144), Expect = 2e-09
Identities = 75/279 (26%), Positives = 114/279 (40%), Gaps = 56/279 (20%)
Query: 18 IYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRG--GPPFAFVEFEDPRDAEDAVYGRD 75
++VGNLP ++R + I + F +YG + + + +RG G AFV+F D + A+ A +
Sbjct: 8 LWVGNLPENVREEKIIEHFKRYGRVESVKILPKRGSEGGVAAFVDFVDIKSAQKA---HN 64
Query: 76 GYDYDGYR-LRVEF------PRSGRG----------TGRGGGGGGGGGAPRGRYGPPSR- 117
+ G R LR ++ P + RG + G GGGG P YGPP
Sbjct: 65 SVNKMGDRDLRTDYNEPGTIPSAARGLDDTVSIASRSREVSGFRGGGGGPA--YGPPPSL 122
Query: 118 -----RSENRVVVSGLPPSGSWQDLKDHMREAGDVCY-------ADVYRDGTGVVEFVRK 165
R E R+ + +++ E G + D YRD E +
Sbjct: 123 HAREGRYERRLDGASDNRERAYEHSAYGHHERGTGGFDRTRHYDQDYYRDPR---ERTLQ 179
Query: 166 EDMTYAVRKLDNTKFRSHEGE-------------TAYIRVKVDGPRSPSYGRSRSRSRSR 212
+ YA R +F +H+ + + D GR R+
Sbjct: 180 HGLYYASRSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDITREVRGRRPERNYQH 239
Query: 213 SRSRSRSNSRSRSYSPRR---SRGSPRYSPRHSRSRSRT 248
SRSRS +S+SR+ SP+R P SP S SRSR+
Sbjct: 240 SRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRS 278
Score = 47.0 bits (110), Expect = 2e-05
Identities = 23/74 (31%), Positives = 40/74 (54%)
Query: 18 IYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGY 77
+++GNL D+ ++F ++G I DID+K G P +AF+++ D A+ DG
Sbjct: 440 LFIGNLEKTTTYHDLRNIFQRFGEIVDIDIKKVNGVPQYAFLQYCDIASVCKAIKKMDGE 499
Query: 78 DYDGYRLRVEFPRS 91
RL++ F +S
Sbjct: 500 YLGNNRLKLGFGKS 513
>gi|20911035 peptidylprolyl isomerase-like 4 [Homo sapiens]
Length = 492
Score = 58.2 bits (139), Expect = 7e-09
Identities = 61/241 (25%), Positives = 96/241 (39%), Gaps = 15/241 (6%)
Query: 18 IYVGNLPPDIRTKDIEDVFYKYGAIRDID-LKNRRGGPP--FAFVEFEDPRDAEDAVYGR 74
++V L P +D+E +F ++G IR + +++ + G +AF+EFE D E A +
Sbjct: 242 LFVCKLNPVTTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFKM 301
Query: 75 DGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSW 134
D D R+ V+F +S G GG + Y + N V+ + P
Sbjct: 302 DNVLIDDRRIHVDFSQSVAKVKWKGKGGKYTKSDFKEYEKEQDKPPNLVLKDKVKPK--- 358
Query: 135 QDLK-----DHMREAGDVCYADVYRDGTGVVEFV--RKEDMTYAVRKLDNTKFRSHEGET 187
QD K D E ++ + KED Y K N G
Sbjct: 359 QDTKYDLILDEQAEDSKSSHSHTSKKHKKKTHHCSEEKEDEDYMPIKNTNQDIYREMGFG 418
Query: 188 AYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSR 247
Y + + S R R+++RSRSRSR R S S+ + + Y S+ R R
Sbjct: 419 HYEEEESCWEKQKSEKRDRTQNRSRSRSRERDGHYSNSHKSKYQ--TDLYERERSKKRDR 476
Query: 248 T 248
+
Sbjct: 477 S 477
>gi|4502847 cold inducible RNA binding protein [Homo sapiens]
Length = 172
Score = 57.0 bits (136), Expect = 1e-08
Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 12/110 (10%)
Query: 13 NNDCRIYVGNLPPDIRTKDIEDVFYKYGAI------RDIDLKNRRGGPPFAFVEFEDPRD 66
+++ +++VG L D + +E VF KYG I +D + + RG F FV FE+ D
Sbjct: 3 SDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRG---FGFVTFENIDD 59
Query: 67 AEDAVYGRDGYDYDGYRLRVE---FPRSGRGTGRGGGGGGGGGAPRGRYG 113
A+DA+ +G DG ++RV+ R G GG GG G RG G
Sbjct: 60 AKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRG 109
>gi|9558733 transformer-2 alpha [Homo sapiens]
Length = 282
Score = 55.8 bits (133), Expect = 3e-08
Identities = 35/101 (34%), Positives = 54/101 (53%), Gaps = 21/101 (20%)
Query: 30 KDIEDVFYKYGAIRDIDLK-NRRGGPP--FAFVEFEDPRDAEDAVYGRDGYDYDGYRLRV 86
+D+ +VF +YG + +++ ++R G FAFV FE D+++A+ +G + DG R+RV
Sbjct: 133 RDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVYFERIDDSKEAMERANGMELDGRRIRV 192
Query: 87 EFP------------------RSGRGTGRGGGGGGGGGAPR 109
++ SG G G GGGGGGGGG R
Sbjct: 193 DYSITKRAHTPTPGIYMGRPTHSGGGGGGGGGGGGGGGGRR 233
Score = 43.9 bits (102), Expect = 1e-04
Identities = 34/66 (51%), Positives = 39/66 (59%), Gaps = 15/66 (22%)
Query: 196 GPRSPS----YGRSRSRSRSRSRSRSRSNS-----RSRSYSP---RRSRG---SPRYSPR 240
G RSPS + S SRSRS+SRSRSR +S RSRS+S RRSR +P Y R
Sbjct: 35 GSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRR 94
Query: 241 HSRSRS 246
SRS S
Sbjct: 95 RSRSHS 100
Score = 41.6 bits (96), Expect = 6e-04
Identities = 35/82 (42%), Positives = 43/82 (52%), Gaps = 18/82 (21%)
Query: 179 KFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSR-------SRSRSNS-------RSR 224
K S G + RV S S+ RSRS+SRSRSR +RSRS+S RSR
Sbjct: 29 KSESRSGSRSPSRVS---KHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSR 85
Query: 225 SYSPR-RSRGSPRYSPRHSRSR 245
SY+P R R S +SP +R R
Sbjct: 86 SYTPEYRRRRSRSHSPMSNRRR 107
Score = 38.1 bits (87), Expect = 0.007
Identities = 30/73 (41%), Positives = 35/73 (47%), Gaps = 16/73 (21%)
Query: 191 RVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSR---------------SYSPRRSRGSP 235
RVK + RS S SR S S SRSRS SRSR S+S RR S
Sbjct: 27 RVKSES-RSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSRSR 85
Query: 236 RYSPRHSRSRSRT 248
Y+P + R RSR+
Sbjct: 86 SYTPEYRRRRSRS 98
Score = 37.0 bits (84), Expect = 0.016
Identities = 28/63 (44%), Positives = 35/63 (55%), Gaps = 13/63 (20%)
Query: 199 SPSYGRSRSRSRSR------------SRSRSRSNSRSRSYSPRRSRGSPRYSPRH-SRSR 245
+P+ +S SRS SR SRSRS+S SRSR +S RR S +S H RSR
Sbjct: 24 TPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHSHRRRSR 83
Query: 246 SRT 248
SR+
Sbjct: 84 SRS 86
Score = 34.7 bits (78), Expect = 0.079
Identities = 19/27 (70%), Positives = 19/27 (70%)
Query: 204 RSRSRSRSRSRSRSRSNSRSRSYSPRR 230
R R RS S SR RS SRSRSYSPRR
Sbjct: 255 RYRRRSPSPYYSRYRSRSRSRSYSPRR 281
Score = 32.7 bits (73), Expect = 0.30
Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
Query: 195 DGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT 248
+G S S +S + + +R +S SRS SRS S R S+ S +S S+SRSR+
Sbjct: 10 EGRESRSQSKSPTGTPARVKSESRSGSRSPS---RVSKHSESHSRSRSKSRSRS 60
Score = 29.6 bits (65), Expect = 2.5
Identities = 18/46 (39%), Positives = 19/46 (41%)
Query: 203 GRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT 248
GR R R R Y RR SP YS SRSRSR+
Sbjct: 231 GRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRS 276
>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
Length = 288
Score = 54.7 bits (130), Expect = 7e-08
Identities = 66/219 (30%), Positives = 84/219 (38%), Gaps = 51/219 (23%)
Query: 15 DCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDL---KNRRGGPPFAFVEFEDPRDAEDAV 71
+C + V L +D+ +VF KYG I D+ + + R FAFV FE+ DA++A
Sbjct: 117 NCCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAK 176
Query: 72 YGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPS 131
+G + DG R+RV+F + R G G R YG RR
Sbjct: 177 ERANGMELDGRRIRVDFSITKRPHTPTPGIYMG----RPTYGSSRRRD------------ 220
Query: 132 GSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIR 191
Y D R D Y R + +R G R
Sbjct: 221 -----------------YYD------------RGYDRGYDDRDYYSRSYRGGGGGGGGWR 251
Query: 192 VKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRR 230
D R Y R RS S SR RS SRSRSYSPRR
Sbjct: 252 AAQD--RDQIY-RRRSPSPYYSRGGYRSRSRSRSYSPRR 287
Score = 48.5 bits (114), Expect = 5e-06
Identities = 35/62 (56%), Positives = 36/62 (58%), Gaps = 6/62 (9%)
Query: 191 RVKVDGPRSPSYGRSRSRSRSRSRSRSR---SNSRSRSYSPRRSRG---SPRYSPRHSRS 244
R K D RS S RSRS SRSRSR SR + SRSRS S RRSR S Y RHS S
Sbjct: 38 RSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHS 97
Query: 245 RS 246
S
Sbjct: 98 HS 99
Score = 42.4 bits (98), Expect = 4e-04
Identities = 27/53 (50%), Positives = 32/53 (60%), Gaps = 3/53 (5%)
Query: 199 SPSYGRSRS---RSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT 248
+P+ RS+ RSRS+SRSRS S SRSR S R S S H RSRSR+
Sbjct: 33 TPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRS 85
Score = 38.5 bits (88), Expect = 0.005
Identities = 25/48 (52%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Query: 198 RSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSR 245
RS +RSRSRSRS RSRS S SR Y R R S +SP +R R
Sbjct: 62 RSSRRHYTRSRSRSRSHRRSRSRSYSRDY---RRRHSHSHSPMSTRRR 106
Score = 32.7 bits (73), Expect = 0.30
Identities = 20/48 (41%), Positives = 29/48 (60%), Gaps = 3/48 (6%)
Query: 201 SYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT 248
+YG SRS SRS S + + +S ++P RSR + R SRS+SR+
Sbjct: 8 NYGERESRSASRSGS-AHGSGKSARHTPARSRS--KEDSRRSRSKSRS 52
Score = 30.0 bits (66), Expect = 2.0
Identities = 18/37 (48%), Positives = 22/37 (59%)
Query: 198 RSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGS 234
RS S+ RSRSRS SR R S+S S + RR G+
Sbjct: 74 RSRSHRRSRSRSYSRDYRRRHSHSHSPMSTRRRHVGN 110
>gi|239752336 PREDICTED: similar to RNA binding motif protein,
X-linked [Homo sapiens]
Length = 138
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/124 (33%), Positives = 54/124 (43%), Gaps = 30/124 (24%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAI------RDIDLKNRRGGPPFAFVEFEDPRDAEDA 70
+ ++G L + K +E VF KYG I +D + RG FAF+ FE P DA+DA
Sbjct: 9 KFFIGGLNTETNKKALEAVFGKYGQIVEVHLMKDCETNKSRG---FAFITFERPADAKDA 65
Query: 71 VYGRDGYDYDGYRLRVEF---------------PRSGRGTGR--GGGGGGGGGAPRGRYG 113
+G DG ++VE P RG R GG GG GG
Sbjct: 66 ARDMNGKSLDGKAIKVEQATKPSFESGRRGPPPPPRSRGPPRVLRGGRGGSGGTRE---- 121
Query: 114 PPSR 117
PPSR
Sbjct: 122 PPSR 125
>gi|239746849 PREDICTED: hypothetical protein XP_002343863 [Homo
sapiens]
Length = 138
Score = 53.5 bits (127), Expect = 2e-07
Identities = 42/124 (33%), Positives = 54/124 (43%), Gaps = 30/124 (24%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAI------RDIDLKNRRGGPPFAFVEFEDPRDAEDA 70
+ ++G L + K +E VF KYG I +D + RG FAF+ FE P DA+DA
Sbjct: 9 KFFIGGLNTETNKKALEAVFGKYGQIVEVHLMKDCETNKSRG---FAFITFERPADAKDA 65
Query: 71 VYGRDGYDYDGYRLRVEF---------------PRSGRGTGR--GGGGGGGGGAPRGRYG 113
+G DG ++VE P RG R GG GG GG
Sbjct: 66 ARDMNGKSLDGKAIKVEQATKPSFESGRRGPPPPPRSRGPPRVLRGGRGGSGGTRE---- 121
Query: 114 PPSR 117
PPSR
Sbjct: 122 PPSR 125
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 53.1 bits (126), Expect = 2e-07
Identities = 55/176 (31%), Positives = 70/176 (39%), Gaps = 7/176 (3%)
Query: 75 DGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGP--PSRRSENRVVVSGLPPSG 132
D D +RL + P G R R G S RS R S S
Sbjct: 819 DSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASS 878
Query: 133 SWQDLKDHMREAGDVCYADVY-RDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIR 191
Q R D Y+D R +D YA K + + + + Y
Sbjct: 879 D-QSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDY-- 935
Query: 192 VKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSR 247
+ +S S RS +R RSRSR RSRS+S SRS S RRSR + +S + SRS SR
Sbjct: 936 -SLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSR 990
Score = 38.1 bits (87), Expect = 0.007
Identities = 33/72 (45%), Positives = 40/72 (55%), Gaps = 7/72 (9%)
Query: 178 TKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRS-RSRSNSRSRSYSPRRSRGSPR 236
++ RSH E + R RS S SRSRS+ RSRS + S RSRSYS RSR S R
Sbjct: 944 SRSRSHTRERSRSR-----GRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSR-STR 997
Query: 237 YSPRHSRSRSRT 248
+ S SR R+
Sbjct: 998 SPSQRSGSRKRS 1009
Score = 36.6 bits (83), Expect = 0.021
Identities = 25/73 (34%), Positives = 34/73 (46%)
Query: 173 RKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSR 232
R+ ++ RS + R K + ++ RSRS SR RSRS + RS S +RS
Sbjct: 951 RERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSW 1010
Query: 233 GSPRYSPRHSRSR 245
G RHS R
Sbjct: 1011 GHESPEERHSGRR 1023
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 52.0 bits (123), Expect = 5e-07
Identities = 31/52 (59%), Positives = 34/52 (65%), Gaps = 1/52 (1%)
Query: 198 RSPSYGRSR-SRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT 248
R+PS R R SRSRSR RS S+S SR RS SPRR R R R SRS S+T
Sbjct: 259 RTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKT 310
Score = 35.8 bits (81), Expect = 0.036
Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 164 RKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSR- 222
R T +K D K RS +Y + S R RSRS +RS + RS R
Sbjct: 305 RSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRK 364
Query: 223 -SRSYSPRRSRGSPRYSPRHSRSR 245
SRS SPRR + + RSR
Sbjct: 365 LSRSPSPRRHKKEKKKDKDKERSR 388
Score = 30.0 bits (66), Expect = 2.0
Identities = 12/17 (70%), Positives = 12/17 (70%)
Query: 89 PRSGRGTGRGGGGGGGG 105
P G G G GGGGGGGG
Sbjct: 15 PSGGPGGGGGGGGGGGG 31
Score = 30.0 bits (66), Expect = 2.0
Identities = 31/91 (34%), Positives = 36/91 (39%), Gaps = 21/91 (23%)
Query: 173 RKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSR---------- 222
R ++ RSH + R K SP RS SR R R RSRS S +R
Sbjct: 268 RSRSRSRRRSHSKSRSRRRSK-----SPRRRRSHSRERGR-RSRSTSKTRDKKKEDKEKK 321
Query: 223 -----SRSYSPRRSRGSPRYSPRHSRSRSRT 248
+SYS R S R RSRS T
Sbjct: 322 RSKTPPKSYSTARRSRSASRERRRRRSRSGT 352
Score = 29.6 bits (65), Expect = 2.5
Identities = 12/18 (66%), Positives = 12/18 (66%)
Query: 89 PRSGRGTGRGGGGGGGGG 106
P G G GGGGGGGGG
Sbjct: 13 PGPSGGPGGGGGGGGGGG 30
Score = 28.5 bits (62), Expect = 5.7
Identities = 12/16 (75%), Positives = 12/16 (75%)
Query: 91 SGRGTGRGGGGGGGGG 106
SG G GGGGGGGGG
Sbjct: 16 SGGPGGGGGGGGGGGG 31
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 52.0 bits (123), Expect = 5e-07
Identities = 36/68 (52%), Positives = 45/68 (66%), Gaps = 3/68 (4%)
Query: 181 RSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPR 240
R ++ Y V+ D RS + RS SRSRSR+RSRSRS++ R Y+ RRSR S YS R
Sbjct: 368 RQQASKSPYNGVRKDSKRSRN-SRSASRSRSRTRSRSRSHTPRRHYNNRRSR-SGTYSSR 425
Query: 241 HSRSRSRT 248
SRSRSR+
Sbjct: 426 -SRSRSRS 432
Score = 43.5 bits (101), Expect = 2e-04
Identities = 30/65 (46%), Positives = 34/65 (52%), Gaps = 19/65 (29%)
Query: 198 RSPSYGRSRSRSRSRSR-----------------SRSRSNSRSRSYSPRR--SRGSPRYS 238
RS S RSR+RSRSRS SRSRS SRS S SPRR + GSP
Sbjct: 390 RSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLK 449
Query: 239 PRHSR 243
+H+R
Sbjct: 450 AKHTR 454
Score = 32.7 bits (73), Expect = 0.30
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 181 RSHEGETAYIRVKV---DGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRY 237
R H + +++ K D S +G R +SRSRS+S+SR +S + R RG R
Sbjct: 439 RHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHS-DAAKKHRHERGHHRD 497
Query: 238 SPRHSRSRSRT 248
SRS R+
Sbjct: 498 RRERSRSFERS 508
Score = 28.9 bits (63), Expect = 4.3
Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 1/76 (1%)
Query: 173 RKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSR 232
R ++ RSH Y + S RSRSRS S S R N S + +R
Sbjct: 396 RSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSES-PRRHHNHGSPHLKAKHTR 454
Query: 233 GSPRYSPRHSRSRSRT 248
+ S RH R ++
Sbjct: 455 DDLKSSNRHGHKRKKS 470
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 51.6 bits (122), Expect = 6e-07
Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 20/116 (17%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDID-LKNRRGGPP--FAFVEFEDPRDAEDAVYG 73
+I+VG + D ++ D F KYG I I+ +++R+ G FAFV F+D D D +
Sbjct: 127 KIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDD-HDTVDKIVV 185
Query: 74 RDGYDYDGYRLRV-------EFPRSGRGTGRGGGGG---------GGGGAPRGRYG 113
+ + +G+ V E +G GRGGG G GGGG GR G
Sbjct: 186 QKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGG 241
Score = 31.6 bits (70), Expect = 0.67
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 72 YGRDGYDYDG---YRLRVEFPRSGRGTGRGGGGGGGGGAPRG 110
+G DG +Y G Y R + G G G GGG GGGG G
Sbjct: 270 FGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDG 311
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 51.6 bits (122), Expect = 6e-07
Identities = 37/57 (64%), Positives = 38/57 (66%), Gaps = 7/57 (12%)
Query: 199 SPSYGRSRSRSRSRSRSRSRSNSRSRSYSPR-RSRGSPR-----YSP-RHSRSRSRT 248
S SY RSRSRS SRS SRSRS SRSRS S R RSR R YSP R RSRSR+
Sbjct: 761 SGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRS 817
Score = 50.1 bits (118), Expect = 2e-06
Identities = 35/63 (55%), Positives = 38/63 (60%), Gaps = 5/63 (7%)
Query: 191 RVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSR----SYSPRRSRGSPR-YSPRHSRSR 245
R K R+ RSRSRS+SR RS SRSNSRS SYS RSR R YS SRSR
Sbjct: 725 RRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSR 784
Query: 246 SRT 248
SR+
Sbjct: 785 SRS 787
Score = 47.8 bits (112), Expect = 9e-06
Identities = 32/57 (56%), Positives = 34/57 (59%), Gaps = 6/57 (10%)
Query: 198 RSPSYGRSRSRSRSRSR------SRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT 248
RS S GRS SRS SRS SRSRS S SRSYS RSR R SRSRS++
Sbjct: 742 RSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQS 798
Score = 43.1 bits (100), Expect = 2e-04
Identities = 29/43 (67%), Positives = 31/43 (72%), Gaps = 3/43 (6%)
Query: 198 RSPSYGRSRSRS-RSRSRSRSRSNSRSRSYSPRRSRGSPRYSP 239
RS S RSRSRS RSRSRS+SR SRS+SYSP R R S SP
Sbjct: 778 RSRSRSRSRSRSSRSRSRSQSR--SRSKSYSPGRRRRSRSRSP 818
Score = 32.3 bits (72), Expect = 0.39
Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 7/52 (13%)
Query: 204 RSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPR-------HSRSRSRT 248
+ R+R R R+ SRSRS S R R S R + R +SRSRSR+
Sbjct: 720 KMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRS 771
>gi|5031703 Ras-GTPase-activating protein SH3-domain-binding protein
[Homo sapiens]
Length = 466
Score = 51.6 bits (122), Expect = 6e-07
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 18/110 (16%)
Query: 17 RIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGG--PPFAFVEFEDPRDAEDAVYGR 74
++++GNLP ++ +++D F YG + ++L+ GG P F FV F+D + + R
Sbjct: 341 QLFIGNLPHEVDKSELKDFFQSYGNV--VELRINSGGKLPNFGFVVFDDSEPVQKVLSNR 398
Query: 75 DGYDYDGYRLRVEFPRS--------------GRGTGRGGGGGGGGGAPRG 110
RL VE ++ G G RGG GGG G PRG
Sbjct: 399 PIMFRGEVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGLGGGMRGPPRG 448
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.139 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,838,491
Number of Sequences: 37866
Number of extensions: 676045
Number of successful extensions: 16834
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 601
Number of HSP's successfully gapped in prelim test: 278
Number of HSP's that attempted gapping in prelim test: 6535
Number of HSP's gapped (non-prelim): 5475
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.