Guide to the Human Genome
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Search of human proteins with 58761537

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58761537 hypothetical protein LOC84437 [Homo sapiens]
         (345 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58761537 hypothetical protein LOC84437 [Homo sapiens]              674   0.0  
gi|239748997 PREDICTED: hypothetical protein XP_002346878 [Homo ...    70   2e-12
gi|239743019 PREDICTED: hypothetical protein XP_002342720 [Homo ...    70   2e-12
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    66   5e-11
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    66   5e-11
gi|62244004 modulator of estrogen induced transcription isoform ...    64   3e-10
gi|63176611 modulator of estrogen induced transcription isoform ...    64   3e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    62   8e-10
gi|56549694 enabled homolog isoform a [Homo sapiens]                   62   1e-09
gi|39930375 enabled homolog isoform b [Homo sapiens]                   62   1e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    61   1e-09
gi|148762940 DVL-binding protein DAPLE [Homo sapiens]                  61   2e-09
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            60   3e-09
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    60   3e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    59   5e-09
gi|148746195 trichohyalin [Homo sapiens]                               59   8e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    58   1e-08
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    57   2e-08
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    57   2e-08
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    57   2e-08
gi|7661936 scaffold attachment factor B2 [Homo sapiens]                56   4e-08
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    55   7e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       55   7e-08
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]                     54   2e-07
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]                     54   2e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    54   2e-07
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub...    54   2e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    54   2e-07
gi|154937324 hypothetical protein LOC440295 [Homo sapiens]             54   2e-07
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap...    54   2e-07

>gi|58761537 hypothetical protein LOC84437 [Homo sapiens]
          Length = 345

 Score =  674 bits (1740), Expect = 0.0
 Identities = 345/345 (100%), Positives = 345/345 (100%)

Query: 1   MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGE 60
           MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGE
Sbjct: 1   MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGE 60

Query: 61  GEQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRND 120
           GEQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRND
Sbjct: 61  GEQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRND 120

Query: 121 ANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDF 180
           ANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDF
Sbjct: 121 ANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDF 180

Query: 181 PHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL 240
           PHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL
Sbjct: 181 PHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL 240

Query: 241 RHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKL 300
           RHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKL
Sbjct: 241 RHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKL 300

Query: 301 ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345
           ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ
Sbjct: 301 ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345


>gi|239748997 PREDICTED: hypothetical protein XP_002346878 [Homo
           sapiens]
          Length = 297

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 65/219 (29%), Positives = 105/219 (47%), Gaps = 29/219 (13%)

Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203
           + + + PQ P     + EE          R   +P          L S  S+S+  +P +
Sbjct: 11  DRQHQLPQQPGSSPPDPEEQRELEPLIRTRRKNIPAPSRFQGLSLLPSCDSKSSASKPQM 70

Query: 204 -----------LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQL 252
                       + +E+  L++E++ L +E   LQVEK+ LQ+E+   R L +E   LQ+
Sbjct: 71  EEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEE---RSLQVEERSLQV 127

Query: 253 EKERLQIEREKLRLQIVNSEKPSLENELG--QGEKSMLQPQDIETEKLKLERERLQLEKD 310
           E++ LQ+E   L++     E+ SL+ E G  Q E+  LQ   +E   L++E   LQ+E+ 
Sbjct: 128 EEKSLQVEERSLQV-----EERSLQVEEGSLQVEEGSLQ---VEEGDLQVEEGGLQVEEG 179

Query: 311 RLQF----LKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345
            LQ     L  E   L +E+  LQVE+  L ++ EG LQ
Sbjct: 180 SLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVE-EGGLQ 217



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 28/163 (17%)

Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKL 264
           + +EK+ L++E+R L +E   LQVE++ LQ+E+   R L +E   LQ+E+  LQ+E   L
Sbjct: 104 LQVEKKSLQVEERSLQVEERSLQVEEKSLQVEE---RSLQVEERSLQVEEGSLQVEEGSL 160

Query: 265 RLQ--IVNSEKPSLENELG--QGEKSMLQPQD----IETEKLKLERERLQLEKDRLQF-- 314
           +++   +  E+  L+ E G  Q E+  L  ++    +E   L++E   L +E+  LQ   
Sbjct: 161 QVEEGDLQVEEGGLQVEEGSLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEE 220

Query: 315 ---------------LKFESEKLQIEKERLQVEKDRLRIQKEG 342
                          L+ E   LQ+E+  LQVEK  L+++K G
Sbjct: 221 GACRWRRGAADGGGGLQMEEGGLQVEEGGLQVEKGGLQVEKGG 263



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 49/165 (29%), Positives = 86/165 (52%), Gaps = 29/165 (17%)

Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLR----HLDMEHERLQLEKERLQIE 260
           + +E++ L++E+R L +E   LQVE+  LQ+E+  L+     L +E   LQ+E+  LQ+E
Sbjct: 125 LQVEEKSLQVEERSLQVEERSLQVEEGSLQVEEGSLQVEEGDLQVEEGGLQVEEGSLQVE 184

Query: 261 REKLRLQI--VNSEKPSLENELG--QGEKSMLQPQD-----------------IETEKLK 299
              L ++   ++ E+  L+ E G    E+  LQ ++                 +E   L+
Sbjct: 185 EGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEEGACRWRRGAADGGGGLQMEEGGLQ 244

Query: 300 LERERLQLEKDRLQF----LKFESEKLQIEKERLQVEKDRLRIQK 340
           +E   LQ+EK  LQ     L+ E   LQ+E+  LQVE+  L++++
Sbjct: 245 VEEGGLQVEKGGLQVEKGGLQVEERDLQVEEGSLQVEERSLQVEE 289



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 21/54 (38%), Positives = 34/54 (62%), Gaps = 4/54 (7%)

Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQ 258
           + +E+  L++EK  L +E   LQVE+  LQ+E+  L+   +E   LQ+E ER+Q
Sbjct: 243 LQVEEGGLQVEKGGLQVEKGGLQVEERDLQVEEGSLQ---VEERSLQVE-ERVQ 292


>gi|239743019 PREDICTED: hypothetical protein XP_002342720 [Homo
           sapiens]
          Length = 487

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 65/219 (29%), Positives = 105/219 (47%), Gaps = 29/219 (13%)

Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203
           + + + PQ P     + EE          R   +P          L S  S+S+  +P +
Sbjct: 201 DRQHQLPQQPGSSPPDPEEQRELEPLIRTRRKNIPAPSRFQGLSLLPSCDSKSSASKPQM 260

Query: 204 -----------LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQL 252
                       + +E+  L++E++ L +E   LQVEK+ LQ+E+   R L +E   LQ+
Sbjct: 261 EEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEE---RSLQVEERSLQV 317

Query: 253 EKERLQIEREKLRLQIVNSEKPSLENELG--QGEKSMLQPQDIETEKLKLERERLQLEKD 310
           E++ LQ+E   L++     E+ SL+ E G  Q E+  LQ   +E   L++E   LQ+E+ 
Sbjct: 318 EEKSLQVEERSLQV-----EERSLQVEEGSLQVEEGSLQ---VEEGDLQVEEGGLQVEEG 369

Query: 311 RLQF----LKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345
            LQ     L  E   L +E+  LQVE+  L ++ EG LQ
Sbjct: 370 SLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVE-EGGLQ 407



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 28/163 (17%)

Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKL 264
           + +EK+ L++E+R L +E   LQVE++ LQ+E+   R L +E   LQ+E+  LQ+E   L
Sbjct: 294 LQVEKKSLQVEERSLQVEERSLQVEEKSLQVEE---RSLQVEERSLQVEEGSLQVEEGSL 350

Query: 265 RLQ--IVNSEKPSLENELG--QGEKSMLQPQD----IETEKLKLERERLQLEKDRLQF-- 314
           +++   +  E+  L+ E G  Q E+  L  ++    +E   L++E   L +E+  LQ   
Sbjct: 351 QVEEGDLQVEEGGLQVEEGSLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEE 410

Query: 315 ---------------LKFESEKLQIEKERLQVEKDRLRIQKEG 342
                          L+ E   LQ+E+  LQVEK  L+++K G
Sbjct: 411 GACRWRRGAADGGGGLQMEEGGLQVEEGGLQVEKGGLQVEKGG 453



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 49/165 (29%), Positives = 86/165 (52%), Gaps = 29/165 (17%)

Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLR----HLDMEHERLQLEKERLQIE 260
           + +E++ L++E+R L +E   LQVE+  LQ+E+  L+     L +E   LQ+E+  LQ+E
Sbjct: 315 LQVEEKSLQVEERSLQVEERSLQVEEGSLQVEEGSLQVEEGDLQVEEGGLQVEEGSLQVE 374

Query: 261 REKLRLQI--VNSEKPSLENELG--QGEKSMLQPQD-----------------IETEKLK 299
              L ++   ++ E+  L+ E G    E+  LQ ++                 +E   L+
Sbjct: 375 EGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEEGACRWRRGAADGGGGLQMEEGGLQ 434

Query: 300 LERERLQLEKDRLQF----LKFESEKLQIEKERLQVEKDRLRIQK 340
           +E   LQ+EK  LQ     L+ E   LQ+E+  LQVE+  L++++
Sbjct: 435 VEEGGLQVEKGGLQVEKGGLQVEERDLQVEEGSLQVEERSLQVEE 479



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 21/54 (38%), Positives = 34/54 (62%), Gaps = 4/54 (7%)

Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQ 258
           + +E+  L++EK  L +E   LQVE+  LQ+E+  L+   +E   LQ+E ER+Q
Sbjct: 433 LQVEEGGLQVEKGGLQVEKGGLQVEERDLQVEEGSLQ---VEERSLQVE-ERVQ 482


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 82/359 (22%), Positives = 165/359 (45%), Gaps = 32/359 (8%)

Query: 2   KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61
           K LK ++++    ++ + L  EI + K+ + + Q N + ++MK  A  ++ + +  + E 
Sbjct: 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQ-NLSKDLMKEKA--QLEKTIETLREN 548

Query: 62  EQRTGT--EVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRN 119
            +R     E +  +L+      R+R + + +         +  L +S+ E   +      
Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608

Query: 120 DANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIE--------EEEEMLSSVIPDS 171
           +     + +  +++ G    E++ E    + ++   + +        E+ E L     + 
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 668

Query: 172 RRENE-----LPDFPHIDEFFTLNSTPSR-SAYDEPHLLV--NIEKQKL-ELEKRRLDIE 222
            REN      L  F ++   F L S     S  DE +L +  N+E  K   ++  +L +E
Sbjct: 669 ERENRKLKKTLDSFKNLT--FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE 726

Query: 223 AERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQ 282
            + L+ EKE+L+   E L+    + ERL++  + L IE ++L+  + NS K   + E   
Sbjct: 727 NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLE--- 783

Query: 283 GEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
              S LQ  ++E + L+   E L++   RL+ L  E E   +E+E  Q+EKD+ +++KE
Sbjct: 784 ---SELQDLEMENQTLQKNLEELKISSKRLEQL--EKENKSLEQETSQLEKDKKQLEKE 837



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 89/368 (24%), Positives = 156/368 (42%), Gaps = 73/368 (19%)

Query: 2   KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61
           K+L+  ++     +E +  L  + K  E++  K  N  I   K  A E+           
Sbjct: 615 KELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQ----------- 663

Query: 62  EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDA 121
                +E++R          RK  K         F L S + ++S  +E  E +  R   
Sbjct: 664 ---ENSELERE--------NRKLKKTLDSFKNLTFQLESLEKENSQLDE--ENLELR--- 707

Query: 122 NFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP 181
               +NV   + A   + ++++E +E +  S + ++++  E+L +    + R      + 
Sbjct: 708 ----RNVESLKCASMKMAQLQLENKELE--SEKEQLKKGLELLKASFKKTERLEV--SYQ 759

Query: 182 HID-EFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERL-QIEKER 239
            +D E   L  T   S      L    E Q LE+E + L    E L++  +RL Q+EKE 
Sbjct: 760 GLDIENQRLQKTLENSNKKIQQL--ESELQDLEMENQTLQKNLEELKISSKRLEQLEKE- 816

Query: 240 LRHLDMEHERLQLEKERLQIEREKLRL----------------QIVNSEK--PSLENELG 281
             +  +E E  QLEK++ Q+E+E  RL                +I N EK   +L  E+G
Sbjct: 817 --NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIG 874

Query: 282 QGEKSMLQPQDIETEKLKLE-------------RERLQLEKDRLQFLKFESEKLQIEKER 328
             ++S ++ +++E E  +L              RE L  EK + Q +  + EKL  E E+
Sbjct: 875 IYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEK 934

Query: 329 LQVEKDRL 336
           + + K+RL
Sbjct: 935 IGLNKERL 942



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 79/368 (21%), Positives = 155/368 (42%), Gaps = 35/368 (9%)

Query: 2    KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61
            K  K+  K N  +++ Q  +K+ T  +  +    L      + +        CV  + E 
Sbjct: 829  KDKKQLEKENKRLRQ-QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVR-LKEL 886

Query: 62   EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDA 121
            E+     VKR  +D + L+  +    + KL        ++DL+  LT E+ EKIG   + 
Sbjct: 887  EKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM---NNDLE-KLTHEL-EKIGLNKER 941

Query: 122  NFDWQNVADFRDAGGSLTEVKVEE--------EERDPQSPEFEIEEE---EEMLSSVIPD 170
                +   D  D+   L E K+E         +E    + E  +EE     + L   +  
Sbjct: 942  LLHDEQSTD--DSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT 999

Query: 171  SRRENELPDFPHIDEFFTLNSTP--------SRSAYDEPHLLVNIEKQKLELEKRRLDIE 222
             ++  E       +E    +S P         R + +    L+ ++ + +E+E+    ++
Sbjct: 1000 VKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQ 1059

Query: 223  AERLQVEKERLQIEKE----RLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLEN 278
            AE+  ++ +  Q+E +    + + L ++ + + L+++   ++ +  +LQ+ NS   S   
Sbjct: 1060 AEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQST 1119

Query: 279  EL-GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLR 337
             L  Q  + ++Q   +E E   + +ER  L K     L  + EKL++  ER   E + L 
Sbjct: 1120 SLMNQNAQLLIQQSSLENENESVIKEREDL-KSLYDSLIKDHEKLELLHERQASEYESL- 1177

Query: 338  IQKEGHLQ 345
            I K G L+
Sbjct: 1178 ISKHGTLK 1185



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 40/186 (21%), Positives = 85/186 (45%), Gaps = 17/186 (9%)

Query: 157 IEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEK 216
           I+E +E   ++I  S   + L   PH        S+ ++S    P +     +Q L +E 
Sbjct: 201 IDERDEHSETIIELSEERDGLHFLPHA-------SSSAQSPCGSPGMKRTESRQHLSVE- 252

Query: 217 RRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSL 276
               +   + ++ + R ++E++  + LD + E      E+++IE ++L+ + +N    + 
Sbjct: 253 ----LADAKAKIRRLRQELEEKTEQLLDCKQEL-----EQMEIELKRLQQENMNLLSDAR 303

Query: 277 ENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336
              + + E   L+ + +  +KL+ E  R +     ++F K   E+L+ + + L   K  L
Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTML 363

Query: 337 RIQKEG 342
             Q EG
Sbjct: 364 EDQLEG 369



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 44/171 (25%), Positives = 73/171 (42%), Gaps = 11/171 (6%)

Query: 145 EEERDPQSPEFEIEEEEEMLSSVIPDSRRENELP---DFPHIDEFFTLNSTPSRSAYDEP 201
           E ERD    + E   EE M   +      +  L    +   I     L+  P +S   E 
Sbjct: 395 EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEV 454

Query: 202 HLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL--QI 259
           + L +    KLE+E + L    E L+   + ++    ++  ++ E++RL  + E L  +I
Sbjct: 455 NELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEI 514

Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKD 310
            +EK  LQ   +    L  E  Q EK+      IET +   ER+   LE++
Sbjct: 515 VQEKQSLQNCQNLSKDLMKEKAQLEKT------IETLRENSERQIKILEQE 559



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 39/157 (24%), Positives = 78/157 (49%), Gaps = 9/157 (5%)

Query: 194 SRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLE 253
           +R+  D+ H    +EK+ L+L+ +  D+E ER  +++++++   E    L+M  ++   E
Sbjct: 370 TRARSDKLH---ELEKENLQLKAKLHDMEMER-DMDRKKIEELMEENMTLEMAQKQSMDE 425

Query: 254 KERLQIEREKLRLQIVNSEKP--SLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDR 311
              L  E E++      SE P  SL +E+ +   S L   ++E + L    E L+   D 
Sbjct: 426 SLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDS 485

Query: 312 LQFLKFESEKLQIEKERLQVEKDRLR---IQKEGHLQ 345
           ++    +  K++ E +RL  + + L    +Q++  LQ
Sbjct: 486 VEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 50/202 (24%), Positives = 91/202 (45%), Gaps = 14/202 (6%)

Query: 147  ERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVN 206
            E + +S   E E+ + +  S+I D  +  EL       E+ +L S          H  + 
Sbjct: 1136 ENENESVIKEREDLKSLYDSLIKDHEKL-ELLHERQASEYESLIS--KHGTLKSAHKNLE 1192

Query: 207  IEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRL 266
            +E + LE    +L  +  +L+  ++ L++E+E++   +  HE +  E ++L  E ++L  
Sbjct: 1193 VEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNH 1252

Query: 267  QIVNSEKPSLENELGQGE----KSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322
                  K   E E+ Q +    KS+L    +E  +L+ E  +L   K++ Q L   S KL
Sbjct: 1253 TYSQLLK---ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKL---KEQYQQLDITSTKL 1306

Query: 323  QIEKERLQVEKDRLRIQKEGHL 344
              + E L   K  L  ++  HL
Sbjct: 1307 NNQCELLSQLKGNLE-EENRHL 1327


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 82/359 (22%), Positives = 165/359 (45%), Gaps = 32/359 (8%)

Query: 2   KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61
           K LK ++++    ++ + L  EI + K+ + + Q N + ++MK  A  ++ + +  + E 
Sbjct: 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQ-NLSKDLMKEKA--QLEKTIETLREN 548

Query: 62  EQRTGT--EVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRN 119
            +R     E +  +L+      R+R + + +         +  L +S+ E   +      
Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608

Query: 120 DANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIE--------EEEEMLSSVIPDS 171
           +     + +  +++ G    E++ E    + ++   + +        E+ E L     + 
Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 668

Query: 172 RRENE-----LPDFPHIDEFFTLNSTPSR-SAYDEPHLLV--NIEKQKL-ELEKRRLDIE 222
            REN      L  F ++   F L S     S  DE +L +  N+E  K   ++  +L +E
Sbjct: 669 ERENRKLKKTLDSFKNLT--FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE 726

Query: 223 AERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQ 282
            + L+ EKE+L+   E L+    + ERL++  + L IE ++L+  + NS K   + E   
Sbjct: 727 NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLE--- 783

Query: 283 GEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
              S LQ  ++E + L+   E L++   RL+ L  E E   +E+E  Q+EKD+ +++KE
Sbjct: 784 ---SELQDLEMENQTLQKNLEELKISSKRLEQL--EKENKSLEQETSQLEKDKKQLEKE 837



 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 89/368 (24%), Positives = 156/368 (42%), Gaps = 73/368 (19%)

Query: 2   KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61
           K+L+  ++     +E +  L  + K  E++  K  N  I   K  A E+           
Sbjct: 615 KELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQ----------- 663

Query: 62  EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDA 121
                +E++R          RK  K         F L S + ++S  +E  E +  R   
Sbjct: 664 ---ENSELERE--------NRKLKKTLDSFKNLTFQLESLEKENSQLDE--ENLELR--- 707

Query: 122 NFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP 181
               +NV   + A   + ++++E +E +  S + ++++  E+L +    + R      + 
Sbjct: 708 ----RNVESLKCASMKMAQLQLENKELE--SEKEQLKKGLELLKASFKKTERLEV--SYQ 759

Query: 182 HID-EFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERL-QIEKER 239
            +D E   L  T   S      L    E Q LE+E + L    E L++  +RL Q+EKE 
Sbjct: 760 GLDIENQRLQKTLENSNKKIQQL--ESELQDLEMENQTLQKNLEELKISSKRLEQLEKE- 816

Query: 240 LRHLDMEHERLQLEKERLQIEREKLRL----------------QIVNSEK--PSLENELG 281
             +  +E E  QLEK++ Q+E+E  RL                +I N EK   +L  E+G
Sbjct: 817 --NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIG 874

Query: 282 QGEKSMLQPQDIETEKLKLE-------------RERLQLEKDRLQFLKFESEKLQIEKER 328
             ++S ++ +++E E  +L              RE L  EK + Q +  + EKL  E E+
Sbjct: 875 IYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEK 934

Query: 329 LQVEKDRL 336
           + + K+RL
Sbjct: 935 IGLNKERL 942



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 43/193 (22%), Positives = 90/193 (46%), Gaps = 23/193 (11%)

Query: 158  EEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKR 217
            ++EE M+ S  P S  +N+                  R + +    L+ ++ + +E+E+ 
Sbjct: 1010 QDEERMVQSSPPISGEDNKW----------------ERESQETTRELLKVKDRLIEVERN 1053

Query: 218  RLDIEAERLQVEKERLQIEKE----RLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEK 273
               ++AE+  ++ +  Q+E +    + + L ++ + + L+++   ++ +  +LQ+ NS  
Sbjct: 1054 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1113

Query: 274  PSLENEL-GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVE 332
             S    L  Q  + ++Q   +E E   + +ER  L K     L  + EKL++  ER   E
Sbjct: 1114 NSQSTSLMNQNAQLLIQQSSLENENESVIKEREDL-KSLYDSLIKDHEKLELLHERQASE 1172

Query: 333  KDRLRIQKEGHLQ 345
             + L I K G L+
Sbjct: 1173 YESL-ISKHGTLK 1184



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 40/186 (21%), Positives = 85/186 (45%), Gaps = 17/186 (9%)

Query: 157 IEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEK 216
           I+E +E   ++I  S   + L   PH        S+ ++S    P +     +Q L +E 
Sbjct: 201 IDERDEHSETIIELSEERDGLHFLPHA-------SSSAQSPCGSPGMKRTESRQHLSVE- 252

Query: 217 RRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSL 276
               +   + ++ + R ++E++  + LD + E      E+++IE ++L+ + +N    + 
Sbjct: 253 ----LADAKAKIRRLRQELEEKTEQLLDCKQEL-----EQMEIELKRLQQENMNLLSDAR 303

Query: 277 ENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336
              + + E   L+ + +  +KL+ E  R +     ++F K   E+L+ + + L   K  L
Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTML 363

Query: 337 RIQKEG 342
             Q EG
Sbjct: 364 EDQLEG 369



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 44/171 (25%), Positives = 73/171 (42%), Gaps = 11/171 (6%)

Query: 145 EEERDPQSPEFEIEEEEEMLSSVIPDSRRENELP---DFPHIDEFFTLNSTPSRSAYDEP 201
           E ERD    + E   EE M   +      +  L    +   I     L+  P +S   E 
Sbjct: 395 EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEV 454

Query: 202 HLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL--QI 259
           + L +    KLE+E + L    E L+   + ++    ++  ++ E++RL  + E L  +I
Sbjct: 455 NELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEI 514

Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKD 310
            +EK  LQ   +    L  E  Q EK+      IET +   ER+   LE++
Sbjct: 515 VQEKQSLQNCQNLSKDLMKEKAQLEKT------IETLRENSERQIKILEQE 559



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 39/157 (24%), Positives = 78/157 (49%), Gaps = 9/157 (5%)

Query: 194 SRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLE 253
           +R+  D+ H    +EK+ L+L+ +  D+E ER  +++++++   E    L+M  ++   E
Sbjct: 370 TRARSDKLH---ELEKENLQLKAKLHDMEMER-DMDRKKIEELMEENMTLEMAQKQSMDE 425

Query: 254 KERLQIEREKLRLQIVNSEKP--SLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDR 311
              L  E E++      SE P  SL +E+ +   S L   ++E + L    E L+   D 
Sbjct: 426 SLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDS 485

Query: 312 LQFLKFESEKLQIEKERLQVEKDRLR---IQKEGHLQ 345
           ++    +  K++ E +RL  + + L    +Q++  LQ
Sbjct: 486 VEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 44/160 (27%), Positives = 74/160 (46%), Gaps = 33/160 (20%)

Query: 213  ELEKRRLDIEAERLQVEKERLQIEKERLRH----LDMEHERLQLE-----KERLQIEREK 263
            +L+ ++++ + E+L  E E++ + KERL H     D  ++ L+ +     K+ L+I+ EK
Sbjct: 915  KLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEK 974

Query: 264  L-----RLQIVNSEKPSLENEL------------GQGEKSMLQPQ-DIETEKLKLERE-- 303
            +     RL+   +    L  EL             Q E+ M+Q    I  E  K ERE  
Sbjct: 975  IAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQ 1034

Query: 304  ----RLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQ 339
                 L   KDRL  ++  +  LQ EK+ L+ +  +L  Q
Sbjct: 1035 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQ 1074



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 50/202 (24%), Positives = 91/202 (45%), Gaps = 14/202 (6%)

Query: 147  ERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVN 206
            E + +S   E E+ + +  S+I D  +  EL       E+ +L S          H  + 
Sbjct: 1135 ENENESVIKEREDLKSLYDSLIKDHEKL-ELLHERQASEYESLIS--KHGTLKSAHKNLE 1191

Query: 207  IEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRL 266
            +E + LE    +L  +  +L+  ++ L++E+E++   +  HE +  E ++L  E ++L  
Sbjct: 1192 VEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNH 1251

Query: 267  QIVNSEKPSLENELGQGE----KSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322
                  K   E E+ Q +    KS+L    +E  +L+ E  +L   K++ Q L   S KL
Sbjct: 1252 TYSQLLK---ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKL---KEQYQQLDITSTKL 1305

Query: 323  QIEKERLQVEKDRLRIQKEGHL 344
              + E L   K  L  ++  HL
Sbjct: 1306 NNQCELLSQLKGNLE-EENRHL 1326


>gi|62244004 modulator of estrogen induced transcription isoform b
           [Homo sapiens]
          Length = 1016

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 47/138 (34%), Positives = 77/138 (55%), Gaps = 35/138 (25%)

Query: 204 LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREK 263
           LV  E+ +  +E RR    AER + E+ER++I +ER      E ERLQ E+ERL+IER+K
Sbjct: 601 LVRFERLRRAMELRRRREIAERERRERERIRIIRER-----EERERLQRERERLEIERQK 655

Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQ 323
           L       E+  +E E                   +LERER+++E++R    + E+E++ 
Sbjct: 656 L-------ERERMERE-------------------RLERERIRIEQER----RKEAERIA 685

Query: 324 IEKERLQVEKDRLRIQKE 341
            E+E L+ ++ +LR ++E
Sbjct: 686 REREELRRQQQQLRYEQE 703



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 62/242 (25%), Positives = 115/242 (47%), Gaps = 28/242 (11%)

Query: 107 LTEEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSS 166
           + +E DEK   R+    D +N +D      S T+  V++EE+  +S E + E++E   + 
Sbjct: 451 MKKENDEKSSSRSSG--DKKNTSD----RSSKTQASVKKEEK--RSSE-KSEKKESKDTK 501

Query: 167 VIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERL 226
            I     +N+        E    +    R +   P  +V +++ K +  +       E++
Sbjct: 502 KIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKI 561

Query: 227 Q---VEKERLQIEKERLRHLDMEHER---LQLEKERLQIEREKL-------RLQIVNSEK 273
                EKER  ++K+R    D ++ R   L  EK + Q  RE L       R   +   +
Sbjct: 562 HGRSKEKERASLDKKR----DKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRR 617

Query: 274 PSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEK 333
              E E  + E+  +  +  E E+L+ ERERL++E+ +L+  + E E+L  E+ER+++E+
Sbjct: 618 EIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERL--ERERIRIEQ 675

Query: 334 DR 335
           +R
Sbjct: 676 ER 677



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 17/96 (17%)

Query: 205 VNIEKQKLE--------LEKRRLDIE------AERLQVEKERLQIEKERLRHLDMEHERL 250
           + IE+QKLE        LE+ R+ IE      AER+  E+E L+ ++++LR+   E E+ 
Sbjct: 649 LEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRY---EQEKR 705

Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKS 286
              K    ++  +       ++K SL+ +   G  S
Sbjct: 706 NSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGS 741


>gi|63176611 modulator of estrogen induced transcription isoform a
           [Homo sapiens]
          Length = 1034

 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 47/138 (34%), Positives = 77/138 (55%), Gaps = 35/138 (25%)

Query: 204 LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREK 263
           LV  E+ +  +E RR    AER + E+ER++I +ER      E ERLQ E+ERL+IER+K
Sbjct: 619 LVRFERLRRAMELRRRREIAERERRERERIRIIRER-----EERERLQRERERLEIERQK 673

Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQ 323
           L       E+  +E E                   +LERER+++E++R    + E+E++ 
Sbjct: 674 L-------ERERMERE-------------------RLERERIRIEQER----RKEAERIA 703

Query: 324 IEKERLQVEKDRLRIQKE 341
            E+E L+ ++ +LR ++E
Sbjct: 704 REREELRRQQQQLRYEQE 721



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 62/242 (25%), Positives = 115/242 (47%), Gaps = 28/242 (11%)

Query: 107 LTEEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSS 166
           + +E DEK   R+    D +N +D      S T+  V++EE+  +S E + E++E   + 
Sbjct: 469 MKKENDEKSSSRSSG--DKKNTSD----RSSKTQASVKKEEK--RSSE-KSEKKESKDTK 519

Query: 167 VIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERL 226
            I     +N+        E    +    R +   P  +V +++ K +  +       E++
Sbjct: 520 KIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKI 579

Query: 227 Q---VEKERLQIEKERLRHLDMEHER---LQLEKERLQIEREKL-------RLQIVNSEK 273
                EKER  ++K+R    D ++ R   L  EK + Q  RE L       R   +   +
Sbjct: 580 HGRSKEKERASLDKKR----DKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRR 635

Query: 274 PSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEK 333
              E E  + E+  +  +  E E+L+ ERERL++E+ +L+  + E E+L  E+ER+++E+
Sbjct: 636 EIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERL--ERERIRIEQ 693

Query: 334 DR 335
           +R
Sbjct: 694 ER 695



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 17/96 (17%)

Query: 205 VNIEKQKLE--------LEKRRLDIE------AERLQVEKERLQIEKERLRHLDMEHERL 250
           + IE+QKLE        LE+ R+ IE      AER+  E+E L+ ++++LR+   E E+ 
Sbjct: 667 LEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRY---EQEKR 723

Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKS 286
              K    ++  +       ++K SL+ +   G  S
Sbjct: 724 NSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGS 759


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 65/325 (20%), Positives = 145/325 (44%), Gaps = 27/325 (8%)

Query: 21  LKEITKRKEVIFSKQLNTTIN----VMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDW 76
           ++E+TK ++ +  +    TI       K    +E  Q V +     Q    E+KR+    
Sbjct: 256 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 315

Query: 77  RALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGG 136
           + L+ +++++A    +G      S+ L   + E            N  W  +   ++   
Sbjct: 316 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE------------NELWNRLNQQQEEKM 363

Query: 137 SLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRS 196
              E K++E E   Q  E +I E+EE +       RR+ E+     + E           
Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM-----MWEKEEKMRRQEEM 418

Query: 197 AYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKER 256
            +++   +   E+   E E++  ++E +  + EK R Q EK +      E E+ Q ++ +
Sbjct: 419 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478

Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316
           +  + EK+R Q    +    E ++ + E+ + + + I  E+ + E+E +  ++++++   
Sbjct: 479 MWRQEEKIREQ--EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR--- 533

Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341
            E E++  +KE++  +++++R Q+E
Sbjct: 534 -EQEEIWRQKEKIHEQEEKIRKQEE 557



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 25/142 (17%), Positives = 90/142 (63%), Gaps = 14/142 (9%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD----MEHERLQLEKERLQIEREK 263
           +K+K+  ++ ++  + E++  ++E++  ++E++R  +     + E+++ ++E+++ + EK
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600

Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRL----QFLKFES 319
           +R Q   +++   E ++G+ E+ M +    + EK++ + E+++ +++++    + ++ + 
Sbjct: 601 IREQEEMTQEQ--EEKMGEQEEKMCE----QEEKMQEQEEKMRRQEEKIREQEKKIREQE 654

Query: 320 EKLQIEKERLQVEKDRLRIQKE 341
           EK++ ++E +Q +++++  Q+E
Sbjct: 655 EKIREQEEMMQEQEEKMWEQEE 676



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 42/206 (20%), Positives = 106/206 (51%), Gaps = 27/206 (13%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K+ E+E   +  E   E+EE++        R+E ++ D                    
Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD--------------QEEKIR 574

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDM----EHERLQLEKE 255
           E    V  +++K+  ++ ++  + E+++ ++E  Q ++E++   +     + E++Q ++E
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634

Query: 256 RLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFL 315
           +++ + EK+R Q    +K   + E  + ++ M+Q Q+   EK+  + E++  +++++Q  
Sbjct: 635 KMRRQEEKIREQ---EKKIREQEEKIREQEEMMQEQE---EKMWEQEEKMCEQEEKMQE- 687

Query: 316 KFESEKLQIEKERLQVEKDRLRIQKE 341
             + EK++ ++E++  ++ RLR Q+E
Sbjct: 688 --QEEKMRRQEEKMWEQEVRLRQQEE 711



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 52/245 (21%), Positives = 113/245 (46%), Gaps = 37/245 (15%)

Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169
           E +EK+  R      W+     R+    + E +   E+ + +  E +I E+E+       
Sbjct: 421 EKEEKM--RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478

Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229
             R+E ++ +                   ++   +   E++  E EK R   E E+ Q E
Sbjct: 479 MWRQEEKIRE-------------QEEKIREQEEKMWRQEEKIHEQEKIR---EEEKRQ-E 521

Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ----------IVNSEKPSLENE 279
           +E +  ++E++R    E E +  +KE++  + EK+R Q          + + E+   E E
Sbjct: 522 QEEMWRQEEKIR----EQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577

Query: 280 ---LGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336
                Q EK   Q + I  ++ K+ RE+ ++ +++ + +  + EK+  ++E++Q +++++
Sbjct: 578 EKVWRQEEKIREQEEKIREQEEKI-REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636

Query: 337 RIQKE 341
           R Q+E
Sbjct: 637 RRQEE 641


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 39/126 (30%), Positives = 77/126 (61%), Gaps = 6/126 (4%)

Query: 216 KRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEK-ERLQIEREKLRLQIVNSEKP 274
           +  L+I+  +LQ ++ + ++E+ERL    ME ERL+ E+ ER ++ERE+L  + +  E+ 
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQ 196

Query: 275 SLENELGQGEKSMLQPQDIETEKLKLERERLQ-LEKDRLQFLKFESEKL----QIEKERL 329
             E +     +  L+ Q+    + +L+RER +  E++RL+ L+ E ++     Q+E+E+L
Sbjct: 197 ERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQL 256

Query: 330 QVEKDR 335
           + E++R
Sbjct: 257 EWERER 262



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 38/126 (30%), Positives = 75/126 (59%), Gaps = 15/126 (11%)

Query: 224 ERLQVEKERLQIEKERLRHLDMEHERLQLEK-ERLQIEREKLRLQIVNSEKPSLENELGQ 282
           E L++++ +LQ   E+ R  ++E ERL+ E+ ER ++ERE+L       E+  LE E  +
Sbjct: 138 EELEIQRRQLQ---EQQRQKELERERLERERMERERLERERL-------ERERLERERLE 187

Query: 283 GEKSMLQPQDIETEKLKLERERLQLEK--DRLQFLKFESEKLQIEKERLQ-VEKDRLRIQ 339
            E+   + Q+ E ++    +ERL+ ++  +R + L  E ++ Q E+ERL+ +E++R   +
Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQERLDRERQERQ-ERERLERLERERQERE 246

Query: 340 KEGHLQ 345
           ++  L+
Sbjct: 247 RQEQLE 252



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 29/92 (31%), Positives = 52/92 (56%), Gaps = 9/92 (9%)

Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQ---LEKDRLQFLK 316
           +  +L  Q+ N   PS E    Q  +   Q +  E E+ +LERER++   LE++RL+  +
Sbjct: 123 QNSQLPAQVQNG--PSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERER 180

Query: 317 FESEKL---QIEKERLQVEKDRLRIQKEGHLQ 345
            E E+L   Q+E+ER + E+   R++++  L+
Sbjct: 181 LERERLEQEQLERERQERERQE-RLERQERLE 211



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 12/162 (7%)

Query: 135 GGSLTEVKVEEEERDPQSPEFEIEEE----EEMLSSVIPDSRRENELPDFPHIDEFFTLN 190
           G S  E++++  +   Q  + E+E E    E M    +   R E E  +   +++     
Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLER 193

Query: 191 STPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERL 250
               R   +       +E+Q+    + RLD E +  Q E+ERL    ERL     E ER 
Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQERQ-ERERL----ERLERERQERER- 247

Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQ--GEKSMLQP 290
           Q + ER Q+E E+ R     +   S+E  L    G+ S  +P
Sbjct: 248 QEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEP 289



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 23/84 (27%), Positives = 53/84 (63%), Gaps = 10/84 (11%)

Query: 266 LQIVNSEK-----PSLENELGQGEKSMLQPQDIETEKLKLERERLQ--LEKDRLQFLKFE 318
           L+++NS++     P   ++L    ++    +++E ++ +L+ ++ Q  LE++RL+  + E
Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERME 167

Query: 319 SEKLQIEKERLQVEK-DRLRIQKE 341
            E+L  E+ERL+ E+ +R R+++E
Sbjct: 168 RERL--ERERLERERLERERLEQE 189


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 39/126 (30%), Positives = 77/126 (61%), Gaps = 6/126 (4%)

Query: 216 KRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEK-ERLQIEREKLRLQIVNSEKP 274
           +  L+I+  +LQ ++ + ++E+ERL    ME ERL+ E+ ER ++ERE+L  + +  E+ 
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQ 196

Query: 275 SLENELGQGEKSMLQPQDIETEKLKLERERLQ-LEKDRLQFLKFESEKL----QIEKERL 329
             E +     +  L+ Q+    + +L+RER +  E++RL+ L+ E ++     Q+E+E+L
Sbjct: 197 ERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQL 256

Query: 330 QVEKDR 335
           + E++R
Sbjct: 257 EWERER 262



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 38/126 (30%), Positives = 75/126 (59%), Gaps = 15/126 (11%)

Query: 224 ERLQVEKERLQIEKERLRHLDMEHERLQLEK-ERLQIEREKLRLQIVNSEKPSLENELGQ 282
           E L++++ +LQ   E+ R  ++E ERL+ E+ ER ++ERE+L       E+  LE E  +
Sbjct: 138 EELEIQRRQLQ---EQQRQKELERERLERERMERERLERERL-------ERERLERERLE 187

Query: 283 GEKSMLQPQDIETEKLKLERERLQLEK--DRLQFLKFESEKLQIEKERLQ-VEKDRLRIQ 339
            E+   + Q+ E ++    +ERL+ ++  +R + L  E ++ Q E+ERL+ +E++R   +
Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQERLDRERQERQ-ERERLERLERERQERE 246

Query: 340 KEGHLQ 345
           ++  L+
Sbjct: 247 RQEQLE 252



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 29/92 (31%), Positives = 52/92 (56%), Gaps = 9/92 (9%)

Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQ---LEKDRLQFLK 316
           +  +L  Q+ N   PS E    Q  +   Q +  E E+ +LERER++   LE++RL+  +
Sbjct: 123 QNSQLPAQVQNG--PSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERER 180

Query: 317 FESEKL---QIEKERLQVEKDRLRIQKEGHLQ 345
            E E+L   Q+E+ER + E+   R++++  L+
Sbjct: 181 LERERLEQEQLERERQERERQE-RLERQERLE 211



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 12/162 (7%)

Query: 135 GGSLTEVKVEEEERDPQSPEFEIEEE----EEMLSSVIPDSRRENELPDFPHIDEFFTLN 190
           G S  E++++  +   Q  + E+E E    E M    +   R E E  +   +++     
Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLER 193

Query: 191 STPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERL 250
               R   +       +E+Q+    + RLD E +  Q E+ERL    ERL     E ER 
Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQERQ-ERERL----ERLERERQERER- 247

Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQ--GEKSMLQP 290
           Q + ER Q+E E+ R     +   S+E  L    G+ S  +P
Sbjct: 248 QEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEP 289



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 23/84 (27%), Positives = 53/84 (63%), Gaps = 10/84 (11%)

Query: 266 LQIVNSEK-----PSLENELGQGEKSMLQPQDIETEKLKLERERLQ--LEKDRLQFLKFE 318
           L+++NS++     P   ++L    ++    +++E ++ +L+ ++ Q  LE++RL+  + E
Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERME 167

Query: 319 SEKLQIEKERLQVEK-DRLRIQKE 341
            E+L  E+ERL+ E+ +R R+++E
Sbjct: 168 RERL--ERERLERERLERERLEQE 189


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 66/325 (20%), Positives = 146/325 (44%), Gaps = 28/325 (8%)

Query: 21  LKEITKRKEVIFSKQLNTTIN----VMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDW 76
           ++E+TK ++ +  +    TI       K    +E  Q V +     Q    E+KR+    
Sbjct: 195 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 254

Query: 77  RALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGG 136
           + L+ +++++A    +G      S+ L   + E            N  W  +   ++   
Sbjct: 255 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE------------NELWNRLNQQQEEKM 302

Query: 137 SLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRS 196
              E K++E E   Q  E +I E+EE +       RR+ E+     + E           
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM-----MWEKEEKMRRQEEM 357

Query: 197 AYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKER 256
            +++   +  +E+   E E++  ++E +  + EK R Q EK +      E E+ Q ++ +
Sbjct: 358 MWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417

Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316
           +  + EK+R Q    +    E ++ + E+ + + + I  E+ + E+E +  ++++++   
Sbjct: 418 MWRQEEKIREQ--EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR--- 472

Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341
            E E++  +KE++  E++++R Q+E
Sbjct: 473 -EQEEIWRQKEKMH-EQEKIRKQEE 495



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 38/208 (18%), Positives = 114/208 (54%), Gaps = 22/208 (10%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K+ E+E+     E +I E+E+     I +  +  E  +    +E         R   +
Sbjct: 429 EEKIREQEKKMWRQEEKIHEQEK-----IREEEKRQEQEEMWRQEEKIREQEEIWRQK-E 482

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259
           + H     E++K+  ++ ++  + E++  ++E+++ ++E++     + E+++ ++E+++ 
Sbjct: 483 KMH-----EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR---QEEKIREQEEKIRE 534

Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI--ETEKLKLERERLQLEKDRL----Q 313
           + EK+R Q    ++   E ++G+ E+ M + + +  + EK++ + E+++ +K+++    +
Sbjct: 535 QEEKIREQEEMMQEQ--EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592

Query: 314 FLKFESEKLQIEKERLQVEKDRLRIQKE 341
            +  + EK++ ++E +Q +++++  Q+E
Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEE 620



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 31/134 (23%), Positives = 85/134 (63%), Gaps = 13/134 (9%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267
           +++K+  ++  +  + E++  ++E++Q E+E++R    + E+++ ++E+++ ++EK+R Q
Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQEEKMQ-EQEKMRR---QEEKIREQEEKIREQKEKIREQ 590

Query: 268 IVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKE 327
               EK   + E  + ++ M+Q Q+   EK+  + E++  +++++Q    + EK++ ++E
Sbjct: 591 ---EEKIWEQEEKIREQEEMMQEQE---EKMWEQEEKMCEQEEKMQE---QEEKMRRQEE 641

Query: 328 RLQVEKDRLRIQKE 341
           ++  ++ RLR Q+E
Sbjct: 642 KMWEQEVRLRQQEE 655



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 39/223 (17%), Positives = 112/223 (50%), Gaps = 16/223 (7%)

Query: 125 WQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHID 184
           W+     R+    + E +   E+ + +  E +I E+E+         R+E ++ +    +
Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ---E 429

Query: 185 EFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD 244
           E             ++ H     E++K+  E++R   E E +  ++E+++ ++E  R  +
Sbjct: 430 EKIREQEKKMWRQEEKIH-----EQEKIREEEKRQ--EQEEMWRQEEKIREQEEIWRQKE 482

Query: 245 MEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQD---IETEKLKLE 301
             HE+ ++ K+  ++ R++ ++     +    E ++ + E+ + + ++    + EK++ +
Sbjct: 483 KMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542

Query: 302 RERLQLEKDRL---QFLKFESEKLQIEKERLQVEKDRLRIQKE 341
            E +Q +++++   +    E EK++ ++E+++ +++++R QKE
Sbjct: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKE 585



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 30/141 (21%), Positives = 83/141 (58%), Gaps = 13/141 (9%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERLQLEKERLQIEREKL 264
           +++K+  ++ ++  + E+++ ++E+++ ++E++R  +    E E    E+E    E+EK+
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566

Query: 265 RLQIVNSEKPSLENELGQGEKSMLQPQDI----ETEKLKLERERLQLEKDRLQFLKFESE 320
           R Q    EK   + E  + +K  ++ Q+     + EK++ + E +Q +++++     + E
Sbjct: 567 RRQ---EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE---QEE 620

Query: 321 KLQIEKERLQVEKDRLRIQKE 341
           K+  ++E++Q +++++R Q+E
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEE 641


>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
          Length = 2028

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 84/363 (23%), Positives = 160/363 (44%), Gaps = 62/363 (17%)

Query: 3   QLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGE 62
           QL+R+++SN   Q+ +TL +E+ + KE     QL + +  +K               +  
Sbjct: 516 QLEREKQSN---QDLETLSEELIREKE-----QLQSDMETLK-------------ADKAR 554

Query: 63  QRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDD-SLTEEIDEKIGFRNDA 121
           Q    E ++ +L+      R+R +     V S   +   + ++ +L + + E  G  +  
Sbjct: 555 QIKDLEQEKDHLNRAMWSLRERSQ-----VSSEARMKDVEKENKALHQTVTEANGKLSQL 609

Query: 122 NFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFE-IEEEEEMLSSVIPDSRRENELPD- 179
            F+ + +   RD    L + K + E  +    E + ++EE   L+  +       E  + 
Sbjct: 610 EFEKRQL--HRD----LEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEA 663

Query: 180 FPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEK--ERLQIEK 237
             H  +   L +   R + D    L N+  Q   LE+    ++AE L++ +  E ++   
Sbjct: 664 LEHESQGLQLENRTLRKSLDT---LQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTS 720

Query: 238 ERLRHLDMEHERLQLEKERL------------QIEREKLRLQIVNSEKPSLENELGQGEK 285
            +L  ++ E+++L+ EKE L            + ER +L  Q V++E   L+  L   E 
Sbjct: 721 TKLAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSL---ES 777

Query: 286 SMLQPQDIETEKLKLERERLQLEKD-------RLQFLKFESEKLQIEKERLQVEKDRLRI 338
           S  + Q +E+E  +LE ER  L +D         Q    E ++  +E+E  Q+EKD+  +
Sbjct: 778 SSHKTQTLESELGELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLL 837

Query: 339 QKE 341
           +KE
Sbjct: 838 EKE 840



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 64/263 (24%), Positives = 108/263 (41%), Gaps = 56/263 (21%)

Query: 103 LDDSLTEEIDEKIGFRNDANFDWQ--NVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEE 160
           L++++  EI +K      A+  W+   ++   D   +  +  V E      S   ++E+E
Sbjct: 412 LEENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKE 471

Query: 161 EEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLD 220
            + L S I   R           D    L  +              ++  +LE E  +L 
Sbjct: 472 NQSLQSTIQGLR-----------DASLVLEES-------------GLKCGELEKENHQLS 507

Query: 221 IEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLR------LQIVNSEKP 274
            + E+LQ + ER   EK+  + L+   E L  EKE+LQ + E L+      ++ +  EK 
Sbjct: 508 KKIEKLQTQLER---EKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKD 564

Query: 275 SLENEL-GQGEKSMLQPQ----DIETEK--------------LKLERERLQLEKDRLQFL 315
            L   +    E+S +  +    D+E E                +LE E+ QL +D  Q  
Sbjct: 565 HLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAK 624

Query: 316 K--FESEKLQIEKERLQVEKDRL 336
           +    +EKL+ E +RLQ E  RL
Sbjct: 625 EKGERAEKLERELQRLQEENGRL 647



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 55/234 (23%), Positives = 100/234 (42%), Gaps = 32/234 (13%)

Query: 139 TEVKVEEEERDPQSPEFEIEE---EEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSR 195
           T  K+ + ER+ Q  E E EE     ++L ++   S R  EL       E   L  +   
Sbjct: 719 TSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERL-ELSYQSVSAENLRLQQSLES 777

Query: 196 SAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKE 255
           S++    L   + + + E +  R D+EA RL       Q+E        +E E  QLEK+
Sbjct: 778 SSHKTQTLESELGELEAERQALRRDLEALRLA----NAQLEGAEKDRKALEQEVAQLEKD 833

Query: 256 RLQIEREKLR------------------LQIVNSEKPSLENELGQGEKSMLQPQDIE--- 294
           +  +E+E  R                  L  V  E  +L+ EL +   +  + +++E   
Sbjct: 834 KKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDN 893

Query: 295 ---TEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345
              T+++ +    L   ++ L   K +S++L  E ++L  E +++ + +E  LQ
Sbjct: 894 RDLTKQVTVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLNRELLLQ 947



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 39/153 (25%), Positives = 74/153 (48%), Gaps = 13/153 (8%)

Query: 192 TPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ 251
           T +R+  D+ H    +EK+ L+L+ +  D+E +R   +K+R++   E    L++  ++  
Sbjct: 371 TAARARGDKVH---ELEKENLQLKSKLHDLELDR-DTDKKRIEELLEENMVLEIAQKQSM 426

Query: 252 LEKERLQIEREKL--RLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLK-----LERER 304
            E   L  E E+L     + ++ + S   EL +   S +   + E + L+     L    
Sbjct: 427 NESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDAS 486

Query: 305 LQLEKDRLQFLKFESEKLQIEK--ERLQVEKDR 335
           L LE+  L+  + E E  Q+ K  E+LQ + +R
Sbjct: 487 LVLEESGLKCGELEKENHQLSKKIEKLQTQLER 519



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 64/271 (23%), Positives = 125/271 (46%), Gaps = 41/271 (15%)

Query: 100  SSDLDDSLTEEIDEKIGFR-------NDANFDWQ-NVADFRDAGGSLTEVKVEEEE---- 147
            SS+LD  L++E+ EK+G         +D+  D +  + + R+     T + ++EE+    
Sbjct: 925  SSELD-KLSQEL-EKVGLNRELLLQEDDSGSDTKYKILEGRNESALKTTLAMKEEKIVLL 982

Query: 148  ----RDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFF------TLNSTPSRSA 197
                 +  S   ++E E +ML     ++ R+N+  +  H+   F      T  S   + A
Sbjct: 983  EAQMEEKASLNRQLESELQMLKKEC-ETLRQNQ-GEGQHLQNSFKHPAGKTAASHQGKEA 1040

Query: 198  YDEPHL-----LVNIEKQKLELEKRRLDIEAERLQVEKERLQ-IEKERL----RHLDMEH 247
            +   H      L+ ++ + +ELE+    ++AE+ Q+ KE+LQ +E + +    + L ++ 
Sbjct: 1041 WGPGHKEATMELLRVKDRAIELERNNAALQAEK-QLLKEQLQHLETQNVTFSSQILTLQK 1099

Query: 248  ERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI--ETEKLKLERERL 305
            +   L++    ++ +  +LQ+ NS   S    L   + ++LQ      ETE   L+R++ 
Sbjct: 1100 QSAFLQEHNTTLQTQTAKLQVENSTLSSQSAAL-TAQYTLLQNHHTAKETENESLQRQQE 1158

Query: 306  QLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336
            QL     + L  + E L    ER   E + L
Sbjct: 1159 QLTA-AYEALLQDHEHLGTLHERQSAEYEAL 1188



 Score = 28.5 bits (62), Expect = 9.2
 Identities = 46/195 (23%), Positives = 77/195 (39%), Gaps = 22/195 (11%)

Query: 138  LTEVKVEEEERDPQSPEFEIEEEEEMLSS---VIPDSRRENELPDFPH------IDEFFT 188
            L   ++ E   D    + E+EE E++L++    +   +R N L    +      +D    
Sbjct: 1204 LEHKELGERHGDMLKRKAELEEREKVLTTEREALQQEQRTNALAMGENQRLRGELDRVNF 1263

Query: 189  LNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHE 248
            L+    +  Y+E H      K  L   +  L+    R    KE+ Q     L  LD   E
Sbjct: 1264 LHHQ-LKGEYEELHAHTKELKTSLNNAQLELNRWQARFDELKEQHQTMDISLTKLDNHCE 1322

Query: 249  RLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLE 308
             L   K  L+ E   L  QI          +L   +  ML  Q++E ++   E ++  + 
Sbjct: 1323 LLSRLKGNLEEENHHLLSQI----------QLLSQQNQMLLEQNMENKEQYHEEQKQYI- 1371

Query: 309  KDRLQFLKFESEKLQ 323
             D+L  L+   EKL+
Sbjct: 1372 -DKLNALRRHKEKLE 1385


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 63/219 (28%), Positives = 103/219 (47%), Gaps = 28/219 (12%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E ++ E+E   +  E  + E+EE L       R + E            L     R    
Sbjct: 198 EERLREQEERLREQEERLREQEERLCEQEERLREQEE-----------RLREQEERLCEQ 246

Query: 200 EPHLLVNIEK-----QKLELEKRRLDIEAERLQVEKERLQIEKERLRH----LDMEHERL 250
           E  L  + E+     ++L  ++ RL  + ERL  ++ERL  ++ERLR     L  + ERL
Sbjct: 247 EERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERL 306

Query: 251 QLEKERLQIEREKLRLQ---IVNSEK-PSLENELGQGEKSMLQPQDIETEKLKLERERLQ 306
           + ++ERL  + E+LR Q   +   EK P  E  L + EK + Q +  E ++  LERERL 
Sbjct: 307 REQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLL 366

Query: 307 LEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345
            E + L     E E+L+ + ERL  ++    +++   L+
Sbjct: 367 EEVEEL----LEQERLRQQDERLWQQETLQELERLRELE 401



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 44/139 (31%), Positives = 82/139 (58%), Gaps = 19/139 (13%)

Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIERE 262
           LL   ++++L  ++ RL  + ERL+ ++ERL  ++ERLR    + ERL+ ++ERL  + E
Sbjct: 192 LLNRRQEERLREQEERLREQEERLREQEERLCEQEERLRE---QEERLREQEERLCEQEE 248

Query: 263 KLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322
           +LR           E  L + E+ + + +    E+L+ + ERL  +++RL     + E+L
Sbjct: 249 RLREH---------EERLCEQEERLCEQE----ERLREQEERLHEQEERLCE---QEERL 292

Query: 323 QIEKERLQVEKDRLRIQKE 341
           + ++ERL  +++RLR Q+E
Sbjct: 293 REQEERLCEQEERLREQEE 311



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 44/132 (33%), Positives = 77/132 (58%), Gaps = 15/132 (11%)

Query: 210 QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIV 269
           Q L L  RR   + ERL+ ++ERL+ ++ERLR    + ERL  ++ERL+ + E+LR Q  
Sbjct: 188 QMLSLLNRR---QEERLREQEERLREQEERLRE---QEERLCEQEERLREQEERLREQ-- 239

Query: 270 NSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERL 329
                  E  L + E+ + + +    E+L  + ERL+ +++RL     + E+L  ++ERL
Sbjct: 240 EERLCEQEERLREHEERLCEQE----ERLCEQEERLREQEERLHE---QEERLCEQEERL 292

Query: 330 QVEKDRLRIQKE 341
           + +++RL  Q+E
Sbjct: 293 REQEERLCEQEE 304



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 43/140 (30%), Positives = 78/140 (55%), Gaps = 26/140 (18%)

Query: 209 KQKLELEKRRLDIEAERLQV-------EKERLQIEKERLRHLDMEHERLQLEKERLQIER 261
           +++LE   R+L  E E  Q+       ++ERL+ ++ERLR    + ERL+ ++ERL  + 
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLRE---QEERLREQEERLCEQE 226

Query: 262 EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321
           E+LR Q         E  L + E+ + + +    E+L+   ERL  +++RL     + E+
Sbjct: 227 ERLREQ---------EERLREQEERLCEQE----ERLREHEERLCEQEERLCE---QEER 270

Query: 322 LQIEKERLQVEKDRLRIQKE 341
           L+ ++ERL  +++RL  Q+E
Sbjct: 271 LREQEERLHEQEERLCEQEE 290



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 40/157 (25%), Positives = 79/157 (50%), Gaps = 10/157 (6%)

Query: 189 LNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHE 248
           +NS    S  ++ H +  ++K    L K + +  AE L  E      + E+L+  +  H 
Sbjct: 112 INSLVRTSKEEKKHEIHLVQKLGRSLFKLK-NQTAEPLAPEPPAGPSKVEQLQD-ETNHL 169

Query: 249 RLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLE 308
           R +LE    Q++ E    Q+++      E  L + E+ + + +    E+L+ + ERL  +
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQE----ERLREQEERLCEQ 225

Query: 309 KDRL----QFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           ++RL    + L+ + E+L  ++ERL+  ++RL  Q+E
Sbjct: 226 EERLREQEERLREQEERLCEQEERLREHEERLCEQEE 262



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 32/84 (38%), Positives = 45/84 (53%), Gaps = 5/84 (5%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD--MEHERLQLEKERLQIEREKLR 265
           E+Q+  LE+ RL  E E L +E+ERL+ + ERL   +   E ERL+  +  L++  E L 
Sbjct: 354 EEQERLLERERLLEEVEEL-LEQERLRQQDERLWQQETLQELERLRELERMLELGWEALY 412

Query: 266 LQIVNSEKPSLENELGQGEKSMLQ 289
            Q   +E  S   EL    KS LQ
Sbjct: 413 EQ--RAEPRSGFEELNNENKSTLQ 434


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 53/146 (36%), Positives = 83/146 (56%), Gaps = 17/146 (11%)

Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL----RHLDMEHERLQLEKERLQ 258
           LL   ++++L  ++ RL  + ERL  ++ERL  ++ERL      L  + ERL+ ++ERL 
Sbjct: 192 LLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLH 251

Query: 259 IEREKLRLQ---IVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFL 315
            + E+L  Q   +   E+   E E   G++ +L+    E EKL LE+ER Q E++RL   
Sbjct: 252 EQEERLCEQEERLCEQEERLCEQEKLPGQERLLE----EVEKL-LEQERRQEEQERL--- 303

Query: 316 KFESEKLQIEKERLQVEKDRLRIQKE 341
             E E+L  E E L +E++RLR Q E
Sbjct: 304 -LERERLLDEVEEL-LEQERLRQQDE 327



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 64/210 (30%), Positives = 94/210 (44%), Gaps = 35/210 (16%)

Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203
           E+EER  +  E   E+EE +         R  E  +  H  E   L     R    E  L
Sbjct: 217 EQEERLCEQEERLCEQEERLREQ----EERLREQEERLHEQEE-RLCEQEERLCEQEERL 271

Query: 204 LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ------LEKERL 257
               E++KL  ++R L+ E E+L +E+ER Q E+ERL    +E ERL       LE+ERL
Sbjct: 272 C---EQEKLPGQERLLE-EVEKL-LEQERRQEEQERL----LERERLLDEVEELLEQERL 322

Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317
           + + E+L  Q    E   L       E   L+    E E+L+     L+L  + L   + 
Sbjct: 323 RQQDERLWQQETLRELERLR------ELERLR----ELERLRELERMLELGWEALYEQRA 372

Query: 318 ES----EKLQIE-KERLQVEKDRLRIQKEG 342
           E     E+L  E K  LQ+E+    ++K G
Sbjct: 373 EPRSGFEELNNENKSTLQLEQQVKELEKSG 402


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 66/334 (19%), Positives = 145/334 (43%), Gaps = 31/334 (9%)

Query: 21  LKEITKRKEVIFSKQLNTTIN----VMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDW 76
           ++E+TK ++ +  +    TI       K    +E  Q V +     Q    E+KR+    
Sbjct: 195 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 254

Query: 77  RALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGG 136
           + L+ +++++A    +G      S+ L   + E            N  W  +   ++   
Sbjct: 255 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE------------NELWNRLNQQQEEKM 302

Query: 137 SLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENEL-----PDFPHIDEFFTLNS 191
              E K++E E   Q  E +I E+EE +       RR+ E+           +E      
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 362

Query: 192 TPSR----SAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEH 247
              R      +++   +   E+   E E++  ++E +  + EK R Q EK +      E 
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422

Query: 248 ERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQL 307
           E+ Q ++ ++  + EK+R Q    +    E ++ + E+ + + + I  E+ + E+E +  
Sbjct: 423 EKRQEQEAKMWRQEEKIREQ--EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480

Query: 308 EKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           +++++     E E++  +KE++  +++++R Q+E
Sbjct: 481 QEEKIH----EQEEIWRQKEKMHEQEEKIRKQEE 510



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 50/253 (19%), Positives = 123/253 (48%), Gaps = 42/253 (16%)

Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169
           E +EKI  R      W+     R+      E K+ E+E      E +I E+EEM      
Sbjct: 500 EQEEKI--RKQEEKVWRQEEKIREQ-----EEKIREQEEKMWRQEEKIREQEEMW----- 547

Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229
             R E ++ +   I E         +    E    +  +++K+  ++ ++  + E+ Q +
Sbjct: 548 --REEEKMHEQEKIWEEEKRQEQEDKMWRQEEK--IREQEEKVWRQEEKIREQEEKRQEQ 603

Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQ 289
           +E++  ++E++R    + E++Q ++E+++ + EK+R Q   +++   E ++G+ E+ M +
Sbjct: 604 EEKMWKQEEKIRE---QEEKIQEQEEKIREQEEKIREQEEMTQEQ--EEKMGEQEEKMCE 658

Query: 290 PQDIETE-----------------KLKLERERLQLEKDRLQFLKF----ESEKLQIEKER 328
            ++   E                 K++ + E+++ +++ +Q  +     + EK+  ++E+
Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718

Query: 329 LQVEKDRLRIQKE 341
           +Q +++++R Q+E
Sbjct: 719 MQEQEEKMRRQEE 731


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 87/382 (22%), Positives = 162/382 (42%), Gaps = 64/382 (16%)

Query: 5    KRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGEQR 64
            +++R+  F  +E +   +   +R+     + L     + +R   +++ +  + + E ++R
Sbjct: 803  RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER 862

Query: 65   TGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGF------- 117
              ++ +RR   WR  ++ +R +    L            +  L +E +E++         
Sbjct: 863  RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922

Query: 118  RNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEF----EIEEEEEMLSSVIPDSRR 173
            R +    ++     +     L   + E+  R  +  ++    +++++EE L    P+ RR
Sbjct: 923  RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982

Query: 174  ENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKL--ELEKRRLDIEAERLQVEKE 231
              E                     Y E   L   E+Q L  E EKRR   E ER   +K+
Sbjct: 983  RQE-----------------REKKYREEEELQQEEEQLLREEREKRRRQ-EWERQYRKKD 1024

Query: 232  RLQIEKERLRHLDMEHERLQLEKERLQIEREKLRL---QIVNSEKPSL-----------E 277
             LQ E+E+L   + E  RLQ E+ER   E E+L+    Q++  E+ +            E
Sbjct: 1025 ELQQEEEQLLREEREKRRLQ-ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083

Query: 278  NELGQGEKSMLQP------------QDIETEKLKLERERL---QLEKDRLQFLKF---ES 319
             EL Q E+ +L+             Q  E E+L+ E E+L   + EK R Q L+    E 
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143

Query: 320  EKLQIEKERLQVEKDRLRIQKE 341
            E++Q E+E+L  E+   R ++E
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQE 1165



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 58/199 (29%), Positives = 92/199 (46%), Gaps = 31/199 (15%)

Query: 142  KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEP 201
            +++E ER  +  E E+++EEE L     ++RR  EL      +E             +E 
Sbjct: 1042 RLQERERQYREEE-ELQQEEEQLLGEERETRRRQELERQYRKEE---------ELQQEEE 1091

Query: 202  HLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIER 261
             LL    +++   E+ R   E E LQ E+E+L + +ER +    E ER   E+E +Q E 
Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQL-LREEREKRRRQELERQYREEEEVQQEE 1150

Query: 262  EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321
            E+L           L  E  +  +  L+ Q  E E+L+ E E         Q L+ E EK
Sbjct: 1151 EQL-----------LREEPEKRRRQELERQYREEEELQQEEE---------QLLREEQEK 1190

Query: 322  LQIEKERLQVEKDRLRIQK 340
             + E+ER   E++ L+ QK
Sbjct: 1191 RRQERERQYREEEELQRQK 1209



 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 56/229 (24%), Positives = 100/229 (43%), Gaps = 27/229 (11%)

Query: 140  EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
            +++ E + +  +  +   E EE+ L     D +   E P     +    L     R   +
Sbjct: 1612 QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671

Query: 200  EPHLLVNIEKQKLELEKRRLDIEAERLQVEK---------ERLQIEKERLRHLDMEHERL 250
            E  LL   E+Q+L  ++R      E  Q+ +         E  Q+ ++ L     E E+L
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731

Query: 251  QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQL--- 307
            + E E+ Q+ R++   +I+  E+   E E  Q  +     +  E E+L+ ERE  QL   
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791

Query: 308  EKDRL----QFLKFESEKLQI-----------EKERLQVEKDRLRIQKE 341
            E DR     + L+ E E+ Q+           E+E+LQ+E+   R+++E
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE 1840



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 43/148 (29%), Positives = 79/148 (53%), Gaps = 21/148 (14%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267
           E+++L+  +R     A++LQ E++ LQ ++ER R  +   +    +K R Q+E E+ R +
Sbjct: 836 EEEQLQRRER-----AQQLQEEEDGLQEDQERRRSQEQRRD----QKWRWQLEEERKRRR 886

Query: 268 IVNSEKPSLENELGQGEKSMLQPQDIETEKLKLE-----------RERLQLEKDRLQFLK 316
                KP+L+ +L + E+ +LQ ++ E ++ + E           RE  QL+++  Q L+
Sbjct: 887 HTLYAKPALQEQLRK-EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945

Query: 317 FESEKLQIEKERLQVEKDRLRIQKEGHL 344
            E EK + ++   Q  KD+   QKE  L
Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQL 973



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 59/223 (26%), Positives = 105/223 (47%), Gaps = 21/223 (9%)

Query: 140 EVKVEEEERDPQSPEFEIEEE--EEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSR-- 195
           +++ E++ER  Q  + E EEE  E+ L     + RRE EL +         + S   +  
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ 705

Query: 196 ----SAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ 251
               S  D     V    +K E ++RR + E +R + E E    E+ER      E E+ +
Sbjct: 706 WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765

Query: 252 LEKERLQIEREKLRLQIVNSEKPSL----ENELGQGEKSMLQPQDIETEKLKLERERLQL 307
               + Q E +  R +   S +P L    E +L   E+   + + +  E+ K +R R + 
Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR 825

Query: 308 EKDR-LQFLKFE--------SEKLQIEKERLQVEKDRLRIQKE 341
           E+++ LQFL+ E        +++LQ E++ LQ +++R R Q++
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 57/211 (27%), Positives = 99/211 (46%), Gaps = 19/211 (9%)

Query: 141 VKVEEEERDPQSPEFEIE---EEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSA 197
           +K+EEEER  Q    E +   E+EE     +     E  L      ++         R  
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE- 547

Query: 198 YDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKER--LRHLDMEHERLQLEKE 255
                LL   E+++LE E+R   ++ E+ +   + L+ E+ER   R    + ERL+   +
Sbjct: 548 ----QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603

Query: 256 RLQIER---EKLRLQIVNSEKPSLENE---LGQGEKSMLQPQDIETEKLKLERERL--QL 307
           R ++ER   E+ R Q +  E+P  E     L   E+   + Q +  E+ +   +RL  + 
Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE 663

Query: 308 EKDRL-QFLKFESEKLQIEKERLQVEKDRLR 337
           E++RL Q LK E E+ + E+E  + E+++ R
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQAR 694



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 52/207 (25%), Positives = 99/207 (47%), Gaps = 16/207 (7%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E ++  E++  +  +   E+EEE         RRE  L       E         R    
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR-----EQEERRDWLKREEET 464

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAER-LQVEKERLQIEKERLRHLDMEHERLQLEKERLQ 258
           E H     E++K +L++ + +   ER L++E+E  + ++ER R   +  E+ +  ++RL+
Sbjct: 465 ERH---EQERRKQQLKRDQEEERRERWLKLEEEERREQQER-REQQLRREQEERREQRLK 520

Query: 259 IEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKD----RLQF 314
            + E+ RLQ     +  L  E  +  + +L+ +  E ++L+ ER   +L+++    R Q 
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKRE--EEKRLEQERREQRLKREQEERRDQL 578

Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341
           LK E E+ Q   +R Q E+   R+++E
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKRE 605



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 55/221 (24%), Positives = 97/221 (43%), Gaps = 38/221 (17%)

Query: 144  EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203
            EE++   Q  E +  EEE++        R+E E       + +        R   +E  L
Sbjct: 1712 EEQQLRRQELERKFREEEQL--------RQETEQEQLRRQERY--------RKILEEEQL 1755

Query: 204  LVNIEKQKLELEKR-RLDIEAERLQVEKERLQI----------EKERLRHLDMEHE---- 248
                E+Q+L  ++R R   E E+L+ E+E  Q+          E+E+LR    E +    
Sbjct: 1756 RPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ 1815

Query: 249  ----RLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI---ETEKLKLE 301
                + + E+E+LQ+E ++ RL+     +   E +    EKS  + Q++   E +K + E
Sbjct: 1816 QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQE 1875

Query: 302  RERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEG 342
            RER   E+   +  K E    Q+ + + Q  K   R+ + G
Sbjct: 1876 RERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPG 1916



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 61/220 (27%), Positives = 93/220 (42%), Gaps = 42/220 (19%)

Query: 144  EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203
            +E ER  +  E E+++EEE L    P+ RR  EL                    Y E   
Sbjct: 1134 QELERQYREEE-EVQQEEEQLLREEPEKRRRQEL-----------------ERQYREEEE 1175

Query: 204  LVNIEKQKL--ELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHE---RLQLEKERLQ 258
            L   E+Q L  E EKRR   E ER   E+E LQ +K + R+ D +     + Q E E+  
Sbjct: 1176 LQQEEEQLLREEQEKRRQ--ERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN 1233

Query: 259  IERE-------KLRLQIVNSEKPSLENELGQGEKSML----QPQDIETEKLKLER----- 302
              R+       +   Q    E   L +   Q +   L    Q +D E E+ + ++     
Sbjct: 1234 AVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293

Query: 303  -ERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
             E  QLE++  +  K    K Q EK+ L+ E++  R ++E
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 55/236 (23%), Positives = 98/236 (41%), Gaps = 37/236 (15%)

Query: 142  KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEP 201
            K  E+E   Q PE +  EEE+ L       +   E       +          R   +E 
Sbjct: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561

Query: 202  HLLVNIEKQKLELEKR----RLDIEAERLQVEKERLQIEKERLR------HLDMEHERLQ 251
             L    E+Q+L  ++R    RL+ +  R Q ++ +   ++++LR       L  E +R  
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621

Query: 252  LEKERLQIEREKLRLQIVNSEKPSLENE--------------------------LGQGEK 285
             E E+L  ERE+ +L     ++  LE E                          L +GE+
Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681

Query: 286  SMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
              L+ Q+    K + E ++L+ ++   +FL+ E +  + E ER   E+++LR + E
Sbjct: 1682 QQLRRQE-RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 59/225 (26%), Positives = 100/225 (44%), Gaps = 41/225 (18%)

Query: 144  EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSR---SAYDE 200
            +E++R     ++E E+E  +  + +    RENE        +F  L  +  R   S  D 
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENE--------QFRQLEDSQLRDRQSQQDL 1267

Query: 201  PHLLVNIEKQKLELEKRRLDI------EAERLQVEKER--------LQIEKERLRHLDME 246
             HLL   +++  E E+RR         E E+L+ E+++         Q EK+ LR    E
Sbjct: 1268 QHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327

Query: 247  HERLQ------LEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKL 300
              R Q       E+E+L  ERE+  L+    ++   E EL   E+           K   
Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG---------RKFLE 1378

Query: 301  ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345
            E +RL+ ++   +FLK E ++L+ ++   Q+ +DR R  +E   Q
Sbjct: 1379 EEQRLRRQERERKFLK-EEQQLRCQEREQQLRQDRDRKFREEEQQ 1422



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 55/213 (25%), Positives = 108/213 (50%), Gaps = 18/213 (8%)

Query: 140 EVKVEEEERDPQSPEFEIEEE--EEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSA 197
           +++ E+EER  Q    E EEE  E+ L     + RRE +L     +     L        
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR------ 391

Query: 198 YDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL 257
             E  L    + ++ +  +R   +  E+    +++L+ E+E  RH + +HE+ + E +RL
Sbjct: 392 --EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH-EQKHEQERRE-QRL 447

Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEK--LKL-ERERLQLEKDRLQF 314
           + E+E+ R   +  E+ +  +E  + ++ + + Q+ E  +  LKL E ER + ++ R Q 
Sbjct: 448 KREQEE-RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506

Query: 315 LKFESEKLQIEKERLQVEKDRL--RIQKEGHLQ 345
           L+ E E+ + ++ + Q E++RL  R++ E  L+
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 46/207 (22%), Positives = 89/207 (42%), Gaps = 23/207 (11%)

Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203
           +EE R+ Q    + EE  E       + RRE +L                      E  L
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQL-------------RREQEEERREQQL 364

Query: 204 LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREK 263
               E+++ E + RR        Q+ +E+    +++LR         QL +E+ Q+ RE+
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ-QLRREQ 423

Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDI---------ETEKLKLERERLQLEKDRLQF 314
              +    E+   ++E  + E+ + + Q+          ETE+ + ER + QL++D+ + 
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483

Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341
            +    KL+ E+ R Q E+   ++++E
Sbjct: 484 RRERWLKLEEEERREQQERREQQLRRE 510



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 50/236 (21%), Positives = 106/236 (44%), Gaps = 10/236 (4%)

Query: 109 EEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVI 168
           EE  ++   R D  F  +   ++R     L + + + +E +PQ      EEEE++     
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283

Query: 169 PDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQV 228
            + RRE +  +     +   L          E       E+++ + E+R    E    Q+
Sbjct: 284 QELRRERQEEE----QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339

Query: 229 EKERLQIEKERLRHLDMEHER---LQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEK 285
            +E+ +  +++LR    E  R   L+ E+E  + E++  R Q +  E+     +  + E+
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399

Query: 286 SMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
            + + Q +  E+ +L RE+ QL +++ Q  + + E+   +K   +  + RL+ ++E
Sbjct: 400 QLRREQQLRREQ-QLRREQ-QLRREQ-QLRREQEEERHEQKHEQERREQRLKREQE 452



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/227 (21%), Positives = 96/227 (42%), Gaps = 25/227 (11%)

Query: 144  EEEERDPQSPEFEIEEEEEMLSSVIPDSR-RENELP------DFPHIDEFFTLNSTPSRS 196
            E E++  Q  + +  EEE+ LS    D + RE E        +   ++E   L     R 
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462

Query: 197  AYDEPHLLVNIEKQKLELEKRRLDIEAERLQV-----------------EKERLQIEKER 239
              +E  LL   E+Q+L  ++R      E  Q+                 E ER  +E+E+
Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522

Query: 240  LRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLK 299
              H      +   E+++L+ +    + +     K   E +L Q  +     +     K +
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582

Query: 300  LERERLQLEKDRLQFLKFESE-KLQIEKERLQVEKDRLRIQKEGHLQ 345
            LE ++++ ++   +F++ E + + Q  +++L+ E+DR   + E  LQ
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 52/214 (24%), Positives = 100/214 (46%), Gaps = 18/214 (8%)

Query: 135 GGSLTEVKVEEEERDPQSPEFEI--------EEEEEMLSSVIPDSRRENELPDFPHIDEF 186
           G   +E +   E+RD Q  + E+        E EE         S + +E  +FP  ++ 
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210

Query: 187 FTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKER-LQIEKERLRHLDM 245
                   R    E       ++Q+ E + R    E E+   ++E  L+ E+E+L+  + 
Sbjct: 211 RRRELLELRRKGREEK-----QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265

Query: 246 EHER-LQLEKERL-QIEREKLRLQIVNSEKPS--LENELGQGEKSMLQPQDIETEKLKLE 301
           + +R LQ E+E+L ++ER++LR +    E+    L  E     K   + ++ + E+ + +
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325

Query: 302 RERLQLEKDRLQFLKFESEKLQIEKERLQVEKDR 335
             R Q E+ R Q L+ E E+ + ++ R + E++R
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEER 359



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 53/225 (23%), Positives = 98/225 (43%), Gaps = 29/225 (12%)

Query: 124  DWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHI 183
            D Q+  D +   G   E   E+E R  Q  +    EEE++      +++R +        
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD-------- 1311

Query: 184  DEFFTLNSTPSRSAYDEPHLL--VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLR 241
                       R + +E  LL     EK++ +   R+   E + LQ  +E+    +ER R
Sbjct: 1312 -----------RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360

Query: 242  HLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLE 301
                E  R Q +  +   E ++LR Q    +    E +L   E+     QD + +  + E
Sbjct: 1361 KFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420

Query: 302  RERLQLEKDRLQFLKFESEKLQI---EKERLQVEKDRLRIQKEGH 343
            ++  + E+DR    KF  E+ Q+   E+ER  +E+++ ++++E H
Sbjct: 1421 QQLSRQERDR----KFREEEQQVRRQERERKFLEEEQ-QLRQERH 1460



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 31/133 (23%), Positives = 66/133 (49%), Gaps = 8/133 (6%)

Query: 213 ELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSE 272
           E + RR ++   R +  +E+ Q  +ER   +  E E  +  K    + +E+ +LQ    E
Sbjct: 207 EEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ---EE 263

Query: 273 KPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVE 332
           +P  + EL + E+ + +      E+ +L RER + E+ + +  + +  + + E+ER + +
Sbjct: 264 EPQRQRELQEEEEQLRK-----LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318

Query: 333 KDRLRIQKEGHLQ 345
           ++R   Q+    Q
Sbjct: 319 EERREQQERREQQ 331



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 47/206 (22%), Positives = 93/206 (45%), Gaps = 10/206 (4%)

Query: 145  EEERDPQSPEFEIEEEEEMLSSVIPDSRRENELP------DFPHIDEFFTLNSTPSRSAY 198
            EE+R  Q  + +  EEE++L        R  E        +  H ++         R   
Sbjct: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR 1385

Query: 199  DEPHLLVNIEKQKLELEKRRLDIEAERLQV--EKERLQIEKERLRHLDMEHERL-QLEKE 255
             E       E+Q+L  ++R   +  +R +   E+E+    +ER R    E +++ + E+E
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445

Query: 256  RLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFL 315
            R  +E E+   Q  + +    E  L + E+  L  Q+ + + L+ E++  + E+DR +F 
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR-KFR 1504

Query: 316  KFESEKLQIEKERLQVEKDRLRIQKE 341
            + E    + E++ L+ E+   R Q++
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQ 1530



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 59/235 (25%), Positives = 96/235 (40%), Gaps = 41/235 (17%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E ++++  R  Q    E EE  E L     + R E E  +                    
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE----------QRLKREQEER 574

Query: 200 EPHLLVNIEKQKLELEKR----RLD-----IEAERLQVEKERLQ------IEKERLRHL- 243
              LL   E+++ +  KR    RL+      E ERL+ E+ R Q       E+ER + L 
Sbjct: 575 RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634

Query: 244 --DMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLE 301
             + + ER Q +  R Q ER + RL+    E+  LE  L +  +   + Q++  E+ +  
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQA 693

Query: 302 RER-----------LQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345
           RER           L+ E D  Q   +   + Q E +R + E++  R ++E  LQ
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQ-EGQRRRQEQEEKRRRRESELQ 747



 Score = 35.4 bits (80), Expect = 0.075
 Identities = 53/221 (23%), Positives = 99/221 (44%), Gaps = 24/221 (10%)

Query: 133 DAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNST 192
           D   SL + + +EE++    P     EEE           +E EL +     E       
Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ 163

Query: 193 PSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQI----------EKERLRH 242
             R   DE      + +Q+ E ++R      E  + E+E+LQ           ++E+LR 
Sbjct: 164 RDRQRRDE-----ELWRQRQEWQER------EERRAEEEQLQSCKGHETEEFPDEEQLRR 212

Query: 243 LDMEHERLQLEKERLQIEREKL-RLQIVNSEKPSLENE-LGQGEKSMLQPQDIETEKLKL 300
            ++   R +  +E+ Q  RE+  R+     EK   + E + + E+  LQ ++ + ++ +L
Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR-EL 271

Query: 301 ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           + E  QL K   Q L+ E ++ + +++RL+ E+   R Q+E
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 27/122 (22%), Positives = 64/122 (52%), Gaps = 3/122 (2%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267
           E+++ +L + + +   +RL+ E+E  ++E+   R  + E    +L +E  +  RE+++ +
Sbjct: 641 ERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR 700

Query: 268 IVNSEKPSLENEL-GQGEKSMLQPQDIETEKLKLERERLQLEKD-RLQFLKFESEKLQIE 325
           I   +   LE+E   +  K   +P+  E ++ + E+E  +  ++  LQ+ + E    Q +
Sbjct: 701 IPKWQW-QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ 759

Query: 326 KE 327
           +E
Sbjct: 760 EE 761



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 37/183 (20%), Positives = 77/183 (42%), Gaps = 31/183 (16%)

Query: 142 KVEEEERDPQSPEFEIEEEE---EMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAY 198
           ++E+EER  Q  + E  EEE   ++L S   + RR+ +L                     
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL--------------------- 647

Query: 199 DEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQ 258
                    E+Q+   ++ + + E ERL+   +R   E+ R + L  E +    E+ + +
Sbjct: 648 -------RREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR 700

Query: 259 IEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFE 318
           I + + +L+     + S      + ++   + Q+ E ++ + E E    E++R    + E
Sbjct: 701 IPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE 760

Query: 319 SEK 321
            E+
Sbjct: 761 EEQ 763


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 58/224 (25%), Positives = 114/224 (50%), Gaps = 21/224 (9%)

Query: 125 WQNVADFRDAGGSLTEV--KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPH 182
           W+     R+  G + E   K+  +E+  +  E E+ E+E+ L        +E ++ +   
Sbjct: 258 WRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 317

Query: 183 -IDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLR 241
            + E            + +   L   EKQ  E E++  D E ER+  + ERL+ ++ER+R
Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE-ERMWEQDERLREKEERMR 376

Query: 242 HLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENE---LGQGEKSMLQPQDI-ETEK 297
               E E++  ++E++Q E E++R      EK   E E     Q EK   Q +++ E E+
Sbjct: 377 ----EQEKMWEQEEKMQ-EEERIR----EREKKMREEEETMREQEEKMQKQEENMWEQEE 427

Query: 298 LKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
            + +++RL  +K++L    +E EK+Q ++E++  +++++R Q+E
Sbjct: 428 KEWQQQRLPEQKEKL----WEQEKMQEQEEKIWEQEEKIRDQEE 467



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 39/224 (17%), Positives = 116/224 (51%), Gaps = 24/224 (10%)

Query: 125 WQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHID 184
           W+     RD      E K+ ++E      +  + E+EE +       ++E ++ +     
Sbjct: 489 WEQEEKMRDQ-----EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543

Query: 185 EFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD 244
           E         +  +D+   +   E++++   ++++  E E ++ ++E++Q ++E++R  +
Sbjct: 544 E-------QEKKTWDQEEKMR--EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594

Query: 245 M----EHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI---ETEK 297
                + E++Q ++E++  + EK+  Q    +    E  + + E+ M + ++    + EK
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654

Query: 298 LKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           ++ + E+++ +++++Q    + EK++ ++E++Q +++++R Q+E
Sbjct: 655 MREQEEKMREQEEKMQG---QEEKMREQEEKMQGQEEKMREQEE 695



 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 73/352 (20%), Positives = 158/352 (44%), Gaps = 44/352 (12%)

Query: 1   MKQLKRK-RKSNFSVQETQT--LLKEITKRKEVIFSKQLNTTINVMKRMAW---EEIAQC 54
           +K+LKRK  ++ F + + QT  L +E+ +++E +  ++    I   +   W   E + + 
Sbjct: 210 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL--REQEKKIRKQEEKMWRQEERLREQ 267

Query: 55  VNAVGEGEQRTGTEVKRRYLDWRALMKR-KRMKANIKLVGSGFPLPSSDL----DDSLTE 109
              + E E++   + KR     + L ++ K ++   KL      +   +      +    
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327

Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169
           E +EK+ +R +    W+     R+      E K+ ++E      +  + E+EE +     
Sbjct: 328 EQEEKM-WRQEERL-WEQEKQMREQ-----EQKMRDQEERMWEQDERLREKEERMREQEK 380

Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229
              +E ++ +   I E              E    +  +++K++ ++  +  E E  + +
Sbjct: 381 MWEQEEKMQEEERIRE--------REKKMREEEETMREQEEKMQKQEENM-WEQEEKEWQ 431

Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQ 289
           ++RL  +KE+L     E E++Q ++E++  + EK+R Q         E   GQ +K   Q
Sbjct: 432 QQRLPEQKEKL----WEQEKMQEQEEKIWEQEEKIRDQ---------EEMWGQEKKMWRQ 478

Query: 290 PQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
            +  E E    E+E     +D+ Q +  + E++  + ERL+ +++R+R QK+
Sbjct: 479 EKMREQEDQMWEQEEKM--RDQEQKMWDQEERMWEQDERLREKEERMREQKK 528



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 35/134 (26%), Positives = 75/134 (55%), Gaps = 16/134 (11%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267
           E Q  E E++  D E +++  ++ER+  + ERLR    E E    E++++  + EK+R  
Sbjct: 485 EDQMWEQEEKMRDQE-QKMWDQEERMWEQDERLR----EKEERMREQKKMWQQEEKMR-- 537

Query: 268 IVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKE 327
               EK + E E    +K+  Q + +  E+   ERE+   E++ +  ++ + EK+Q ++E
Sbjct: 538 ---EEKKTQEQE----KKTWDQEEKMREEERMREREKKMREEEEM--MREQEEKMQEQEE 588

Query: 328 RLQVEKDRLRIQKE 341
           +++ +++++  Q+E
Sbjct: 589 KMREQEEKMWEQEE 602



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 49/233 (21%), Positives = 108/233 (46%), Gaps = 30/233 (12%)

Query: 109 EEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVI 168
           E + EK     +    WQ     R+      E K +E+E+     E ++ EEE M     
Sbjct: 514 ERLREKEERMREQKKMWQQEEKMRE------EKKTQEQEKKTWDQEEKMREEERMRERE- 566

Query: 169 PDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQV 228
              R E E+      ++   +     +    E  +    EK + + EK     E    Q 
Sbjct: 567 KKMREEEEMMR----EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622

Query: 229 EKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSML 288
           E++++Q ++E +     + E++Q ++E++  + EK+R Q    EK   + E  QG++   
Sbjct: 623 EEDKMQEQEEMMWE---QEEKMQEQEEKMWEQEEKMREQ---EEKMREQEEKMQGQE--- 673

Query: 289 QPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
                  EK++ + E++Q +++++   + + EK++ ++E++  +++++  Q+E
Sbjct: 674 -------EKMREQEEKMQGQEEKM---REQEEKMRGQEEKMWGQEEKMWGQEE 716



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 40/141 (28%), Positives = 73/141 (51%), Gaps = 17/141 (12%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQ--IEREKLR 265
           E+  L LE  R  I  E L+ +   LQ   E+LR  + E   +QL  + L+  +ER K  
Sbjct: 167 ERDALSLELYRNTITNEELKKKNAELQ---EKLRLAESEKSEIQLNVKELKRKLERAKFL 223

Query: 266 LQIVNS-----EKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESE 320
           L  V +     E    E EL + EK + +    + EK+  + ERL+ ++ +   ++ + E
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRK----QEEKMWRQEERLREQEGK---MREQEE 276

Query: 321 KLQIEKERLQVEKDRLRIQKE 341
           K++ +++RL+ ++  LR Q++
Sbjct: 277 KMRRQEKRLREQEKELREQEK 297


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 69/348 (19%), Positives = 160/348 (45%), Gaps = 51/348 (14%)

Query: 6   RKRKSNFSVQETQ---------TLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVN 56
           +KR  N  ++ET          T ++++TK ++ +  +    TI        EE+ +   
Sbjct: 168 QKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITD------EELKEKNA 221

Query: 57  AVGEGEQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIG 116
            + E  +   +E     L+ + L KRK  +A + L      + +  L   L + +  K+ 
Sbjct: 222 ELQEKLRLVESEKSEIQLNVKDL-KRKLERAQLLLPQQQLQVEADRLGKEL-QSVSAKLQ 279

Query: 117 FRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENE 176
            + + N  W  +   ++      E K++E+E      E +I E+EE +       R+E +
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKM------WRQEEK 333

Query: 177 LPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIE 236
           +                      E    +  ++ K+  ++ ++  + E+++ ++E++  +
Sbjct: 334 M---------------------HEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372

Query: 237 KERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENE---LGQGEKSMLQPQDI 293
           +E++R  D   E++Q ++E +  + EK+R Q    ++     E     Q EK   Q +++
Sbjct: 373 EEKIREQD---EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429

Query: 294 ETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
             ++ K+ RE  ++ +D+ + L+   EK+Q E+E++Q ++++++ Q+E
Sbjct: 430 WRQEEKI-RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 53/232 (22%), Positives = 114/232 (49%), Gaps = 32/232 (13%)

Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169
           E +EKI  R      W+     R+      + K++E+E +    E +I E+EE     + 
Sbjct: 357 EQEEKI--REQEEKMWRQEEKIREQ-----DEKIQEQEEEMWRQEEKIREQEEKRQEKM- 408

Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229
             R+E ++ +                   ++   +   E++  ELE+   D E E+L+  
Sbjct: 409 -WRQEKKMRE-------------QDEKIREQEEEMWRQEEKIRELEEMMQDQE-EKLREV 453

Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ--IVNSEKPSLENE---LGQGE 284
           +E++Q E+E+++    + E++Q ++E++Q + EK   Q  ++  E+   E E     Q E
Sbjct: 454 EEKMQEEEEKMQE---QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510

Query: 285 KSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336
           K   Q + ++ ++ K++R+  ++ +  ++  + + EK+Q ++ RLQ  ++RL
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQ-QEEKMQEQEVRLQELEERL 561



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 45/207 (21%), Positives = 107/207 (51%), Gaps = 18/207 (8%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K+ E+E      E +I E+EE +        R+ E       DE   +          
Sbjct: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE--KIREQDE--KIQEQEEEMWRQ 393

Query: 200 EPHLLVNIEK--QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL 257
           E  +    EK  +K+  +++++  + E+++ ++E +  ++E++R L+   E +Q ++E+L
Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE---EMMQDQEEKL 450

Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIET---EKLKLERERLQLEKDRLQF 314
           +   EK++ +    EK   + E  Q ++  +Q Q+ +T   EKL  + E++  +++++  
Sbjct: 451 REVEEKMQEE---EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507

Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341
              + EK+  ++E++Q ++++++ Q+E
Sbjct: 508 ---QEEKMWEQEEKMQEQEEKMQRQEE 531



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 49/204 (24%), Positives = 93/204 (45%), Gaps = 38/204 (18%)

Query: 164 LSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEA 223
           L  V    R EN L     ++E    +       Y E    +  E+  L LE  R  I  
Sbjct: 162 LGEVTAQKRPENSL-----LEETLHFDHAVRMGTYIEK---LTKERDALSLELYRNTITD 213

Query: 224 ERLQVEKERLQIEKERLRHLDMEHERLQLE----------------KERLQIEREKL--R 265
           E L+ +   LQ   E+LR ++ E   +QL                 +++LQ+E ++L   
Sbjct: 214 EELKEKNAELQ---EKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270

Query: 266 LQIVNSEKPSL--ENEL------GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317
           LQ V+++  +   ENEL       Q EK   Q + I+ ++ K+  + L++ +   +  + 
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR- 329

Query: 318 ESEKLQIEKERLQVEKDRLRIQKE 341
           + EK+  ++E+++ ++D++  Q+E
Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEE 353



 Score = 32.3 bits (72), Expect = 0.64
 Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 12/152 (7%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDS-RRENELPDFPHIDEFFTLNSTPSRSAY 198
           E K++EEE   Q  E +I+ +EE +      + R+E  L     I E            +
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMW 513

Query: 199 DEPHLLVNIEK------QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERL-- 250
           ++   +   E+      +K+  ++ RL  + E++Q ++ RLQ  +ERL  L  + E L  
Sbjct: 514 EQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573

Query: 251 ---QLEKERLQIEREKLRLQIVNSEKPSLENE 279
              +   +RL      L++++ + E  SL+ +
Sbjct: 574 AGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 59/216 (27%), Positives = 104/216 (48%), Gaps = 20/216 (9%)

Query: 132 RDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP--HIDEFFTL 189
           ++    L   KVEE++R  +  E +++ EE  L  V+    R  ++ +     I++ F  
Sbjct: 548 KEEAEQLRRQKVEEDKRR-RLEEVKLKREER-LRKVLQARERVEQMKEEKKKQIEQKFAQ 605

Query: 190 NSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKER----LQIEKERLRHLDM 245
               +  A +E   L   + +K    K+  ++EA R Q E+ R    LQ E+E  RH ++
Sbjct: 606 IDEKTEKAKEER--LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 663

Query: 246 EHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERL 305
             ++ + E+ERL+   E  RL     ++     E  + E+   + +  E E+ + ER+  
Sbjct: 664 LQKKKEEEQERLRKAAEAKRLA---EQREQERREQERREQERREQERREQERREQERQLA 720

Query: 306 QLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           + E+ R      E E+LQ E+E LQ  +  LR+QKE
Sbjct: 721 EQERRR------EQERLQAERE-LQEREKALRLQKE 749



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 39/144 (27%), Positives = 79/144 (54%), Gaps = 15/144 (10%)

Query: 207 IEKQKLELEKRRLDIEAERLQVEK----ERLQIEK------ERLRHLDMEHERLQLEKER 256
           +EK++  LE  R   EAE+L+ +K    +R ++E+      ERLR +    ER++  KE 
Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 594

Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316
            + + E+   QI    + + E  L + EK+  +    + E+++  R++ + E  RL++L+
Sbjct: 595 KKKQIEQKFAQIDEKTEKAKEERLAE-EKAKKKAAAKKMEEVEARRKQ-EEEARRLRWLQ 652

Query: 317 FESEK---LQIEKERLQVEKDRLR 337
            E E+    ++ +++ + E++RLR
Sbjct: 653 QEEEERRHQELLQKKKEEEQERLR 676



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 53/195 (27%), Positives = 85/195 (43%), Gaps = 21/195 (10%)

Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169
           +IDEK     +     +  A  + A   + EV+   ++ +       +++EEE       
Sbjct: 605 QIDEKTEKAKEERLA-EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE------- 656

Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229
             RR  EL      +E   L          E       E+++ E E+R  +   E+ + E
Sbjct: 657 -ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE-RREQERRE 714

Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQ 289
           +ER   E+ER R    E ERLQ E+E LQ   + LRLQ     K  L+ EL + +K   Q
Sbjct: 715 QERQLAEQERRR----EQERLQAERE-LQEREKALRLQ-----KEQLQRELEEKKKKEEQ 764

Query: 290 PQDIETEKLKLERER 304
            Q +   +L+ E+E+
Sbjct: 765 -QRLAERQLQEEQEK 778



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 40/156 (25%), Positives = 72/156 (46%), Gaps = 16/156 (10%)

Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSR----RENELPDFPHIDEFFTLNSTPSRSAYD 199
           EEE R  +  + + EEE+E L       R    RE E  +    ++         +   +
Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259
           +       E+Q  E E+RR   E ERLQ E+E LQ E+E+   L  E  + +LE+++ + 
Sbjct: 715 Q-------ERQLAEQERRR---EQERLQAERE-LQ-EREKALRLQKEQLQRELEEKKKKE 762

Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIET 295
           E+++L  + +  E+     E     K++    D+++
Sbjct: 763 EQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 798



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 25/137 (18%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ----------LEKERL 257
           +K++ E E+ R   EA+RL  ++E+ + E+ER      E ER +           E+ER 
Sbjct: 666 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER- 724

Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSM-LQPQDIETEKLKLERERLQLEKDRLQFLK 316
              RE+ RLQ         E EL + EK++ LQ + ++ E   LE ++ + E+ RL   +
Sbjct: 725 --RREQERLQ--------AERELQEREKALRLQKEQLQRE---LEEKKKKEEQQRLAERQ 771

Query: 317 FESEKLQIEKERLQVEK 333
            + E+ +  KE     K
Sbjct: 772 LQEEQEKKAKEAAGASK 788



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 23/87 (26%), Positives = 47/87 (54%), Gaps = 11/87 (12%)

Query: 265 RLQIVNSEKPSLENELGQGEKSMLQPQDIETEK------LKLERE----RLQLEKDRLQF 314
           +   V  E+  LEN   + E   L+ Q +E +K      +KL+RE    ++   ++R++ 
Sbjct: 531 KCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQ 590

Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341
           +K E +K QIE++  Q+++   + ++E
Sbjct: 591 MK-EEKKKQIEQKFAQIDEKTEKAKEE 616


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 59/216 (27%), Positives = 104/216 (48%), Gaps = 20/216 (9%)

Query: 132 RDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP--HIDEFFTL 189
           ++    L   KVEE++R  +  E +++ EE  L  V+    R  ++ +     I++ F  
Sbjct: 544 KEEAEQLRRQKVEEDKRR-RLEEVKLKREER-LRKVLQARERVEQMKEEKKKQIEQKFAQ 601

Query: 190 NSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKER----LQIEKERLRHLDM 245
               +  A +E   L   + +K    K+  ++EA R Q E+ R    LQ E+E  RH ++
Sbjct: 602 IDEKTEKAKEER--LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 659

Query: 246 EHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERL 305
             ++ + E+ERL+   E  RL     ++     E  + E+   + +  E E+ + ER+  
Sbjct: 660 LQKKKEEEQERLRKAAEAKRLA---EQREQERREQERREQERREQERREQERREQERQLA 716

Query: 306 QLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           + E+ R      E E+LQ E+E LQ  +  LR+QKE
Sbjct: 717 EQERRR------EQERLQAERE-LQEREKALRLQKE 745



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 53/195 (27%), Positives = 85/195 (43%), Gaps = 21/195 (10%)

Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169
           +IDEK     +     +  A  + A   + EV+   ++ +       +++EEE       
Sbjct: 601 QIDEKTEKAKEERLA-EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE------- 652

Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229
             RR  EL      +E   L          E       E+++ E E+R  +   E+ + E
Sbjct: 653 -ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE-RREQERRE 710

Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQ 289
           +ER   E+ER R    E ERLQ E+E LQ   + LRLQ     K  L+ EL + +K   Q
Sbjct: 711 QERQLAEQERRR----EQERLQAERE-LQEREKALRLQ-----KEQLQRELEEKKKKEEQ 760

Query: 290 PQDIETEKLKLERER 304
            Q +   +L+ E+E+
Sbjct: 761 -QRLAERQLQEEQEK 774



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/143 (27%), Positives = 78/143 (54%), Gaps = 15/143 (10%)

Query: 208 EKQKLELEKRRLDIEAERLQVEK----ERLQIEK------ERLRHLDMEHERLQLEKERL 257
           EK++  LE  R   EAE+L+ +K    +R ++E+      ERLR +    ER++  KE  
Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 591

Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317
           + + E+   QI    + + E  L + EK+  +    + E+++  R++ + E  RL++L+ 
Sbjct: 592 KKQIEQKFAQIDEKTEKAKEERLAE-EKAKKKAAAKKMEEVEARRKQ-EEEARRLRWLQQ 649

Query: 318 ESEK---LQIEKERLQVEKDRLR 337
           E E+    ++ +++ + E++RLR
Sbjct: 650 EEEERRHQELLQKKKEEEQERLR 672



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 40/156 (25%), Positives = 72/156 (46%), Gaps = 16/156 (10%)

Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSR----RENELPDFPHIDEFFTLNSTPSRSAYD 199
           EEE R  +  + + EEE+E L       R    RE E  +    ++         +   +
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 710

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259
           +       E+Q  E E+RR   E ERLQ E+E LQ E+E+   L  E  + +LE+++ + 
Sbjct: 711 Q-------ERQLAEQERRR---EQERLQAERE-LQ-EREKALRLQKEQLQRELEEKKKKE 758

Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIET 295
           E+++L  + +  E+     E     K++    D+++
Sbjct: 759 EQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 794



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 25/137 (18%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ----------LEKERL 257
           +K++ E E+ R   EA+RL  ++E+ + E+ER      E ER +           E+ER 
Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER- 720

Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSM-LQPQDIETEKLKLERERLQLEKDRLQFLK 316
              RE+ RLQ         E EL + EK++ LQ + ++ E   LE ++ + E+ RL   +
Sbjct: 721 --RREQERLQ--------AERELQEREKALRLQKEQLQRE---LEEKKKKEEQQRLAERQ 767

Query: 317 FESEKLQIEKERLQVEK 333
            + E+ +  KE     K
Sbjct: 768 LQEEQEKKAKEAAGASK 784



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 24/88 (27%), Positives = 48/88 (54%), Gaps = 11/88 (12%)

Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDIETEK------LKLERE----RLQLEKDRLQ 313
           LR+     E+  LEN   + E   L+ Q +E +K      +KL+RE    ++   ++R++
Sbjct: 526 LRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVE 585

Query: 314 FLKFESEKLQIEKERLQVEKDRLRIQKE 341
            +K E +K QIE++  Q+++   + ++E
Sbjct: 586 QMK-EEKKKQIEQKFAQIDEKTEKAKEE 612


>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
          Length = 953

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 56/211 (26%), Positives = 105/211 (49%), Gaps = 29/211 (13%)

Query: 139 TEVKVEE--EERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRS 196
           T +K EE  E+++ + PE +I++EE+    + P     + +          T+    S+ 
Sbjct: 521 TVIKKEEKIEKKEEKKPE-DIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKG 579

Query: 197 AYDEPHLLVNIEKQKLELEKRRLDIEAER------LQVEKERLQIEKERLRHLDMEHERL 250
              EP + V    +  E   +  D ++E       L  +K + Q E+ER R  + E    
Sbjct: 580 ---EPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRET 636

Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKD 310
           +  +ER Q ERE+ RL+  +  K          EK+ LQ      E+L+LE +R +LE++
Sbjct: 637 ERRREREQREREQ-RLEAFHERK----------EKARLQ-----RERLQLECQRQRLERE 680

Query: 311 RLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           R++  + E E++++E+ER + E++R+  ++E
Sbjct: 681 RMERERLERERMRVERER-RKEQERIHRERE 710



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 37/140 (26%), Positives = 72/140 (51%), Gaps = 15/140 (10%)

Query: 139 TEVKVEEEERDPQSPEFEIEEEEEMLS-SVIPDSR-------RENELPDFPHIDEFFTLN 190
           T  + +E     Q  + E +E+ ++LS   I + R       RE E+ +     E     
Sbjct: 587 TTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRE 646

Query: 191 STPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQ---VEKERLQIEKERLRHLDMEH 247
                 A+ E      +++++L+LE +R  +E ER++   +E+ER+++E+ER +    E 
Sbjct: 647 REQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRK----EQ 702

Query: 248 ERLQLEKERLQIEREKLRLQ 267
           ER+  E+E L+ ++E+LR +
Sbjct: 703 ERIHREREELRRQQEQLRYE 722


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 53/265 (20%), Positives = 127/265 (47%), Gaps = 35/265 (13%)

Query: 80  MKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGGSLT 139
           +KRK  +A + L      + +  L   L + +  K+  + + N  W  +   ++      
Sbjct: 244 LKRKLERAQLLLPQQQLQVEADRLGKEL-QSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K++E+E      E +I E+EE +       R+E ++                      
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKM------WRQEEKM---------------------H 335

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259
           E    +  ++ K+  ++ ++  + E+++ ++E++  ++E++R  D   E++Q ++E +  
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWR 392

Query: 260 EREKLRLQIVNSEKPSLENE---LGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316
           + EK+R Q    ++     E     Q EK   Q +++  ++ K+ RE  ++ +D+ + L+
Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI-RELEEMMQDQEEKLR 451

Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341
              EK+Q E+E++Q ++++++ Q+E
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEE 476



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 53/232 (22%), Positives = 114/232 (49%), Gaps = 32/232 (13%)

Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169
           E +EKI  R      W+     R+      + K++E+E +    E +I E+EE     + 
Sbjct: 357 EQEEKI--REQEEKMWRQEEKIREQ-----DEKIQEQEEEMWRQEEKIREQEEKRQEKM- 408

Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229
             R+E ++ +                   ++   +   E++  ELE+   D E E+L+  
Sbjct: 409 -WRQEKKMRE-------------QDEKIREQEEEMWRQEEKIRELEEMMQDQE-EKLREV 453

Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ--IVNSEKPSLENE---LGQGE 284
           +E++Q E+E+++    + E++Q ++E++Q + EK   Q  ++  E+   E E     Q E
Sbjct: 454 EEKMQEEEEKMQE---QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510

Query: 285 KSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336
           K   Q + ++ ++ K++R+  ++ +  ++  + + EK+Q ++ RLQ  ++RL
Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQ-QEEKMQEQEVRLQELEERL 561



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 36/170 (21%), Positives = 96/170 (56%), Gaps = 27/170 (15%)

Query: 199 DEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERL-------------QIEKERLRHL-- 243
           ++  + +N++  K +LE+ +L +  ++LQVE +RL             Q+E+  L +L  
Sbjct: 233 EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLN 292

Query: 244 DMEHERLQLEKERLQIEREKL---RLQIVNSEKPSL--ENELGQGEKSMLQPQDI---ET 295
             + E++  ++E++Q + EK+    L+I   E+     E ++ + E+ + + +D    + 
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352

Query: 296 EKLKLERERLQLEKDRL----QFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           EK++ + E+++ +++++    + ++ + EK+Q ++E +  +++++R Q+E
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 45/207 (21%), Positives = 107/207 (51%), Gaps = 18/207 (8%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K+ E+E      E +I E+EE +        R+ E       DE   +          
Sbjct: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE--KIREQDE--KIQEQEEEMWRQ 393

Query: 200 EPHLLVNIEK--QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL 257
           E  +    EK  +K+  +++++  + E+++ ++E +  ++E++R L+   E +Q ++E+L
Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE---EMMQDQEEKL 450

Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIET---EKLKLERERLQLEKDRLQF 314
           +   EK++ +    EK   + E  Q ++  +Q Q+ +T   EKL  + E++  +++++  
Sbjct: 451 REVEEKMQEE---EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507

Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341
              + EK+  ++E++Q ++++++ Q+E
Sbjct: 508 ---QEEKMWEQEEKMQEQEEKMQRQEE 531



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 48/204 (23%), Positives = 92/204 (45%), Gaps = 38/204 (18%)

Query: 164 LSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEA 223
           L  V    R EN L     ++E    +       Y E    +  E+    LE  R  I  
Sbjct: 162 LGEVTAQKRPENSL-----LEETLHFDHAVRMGTYIEK---LTKERDAPSLELYRNTITD 213

Query: 224 ERLQVEKERLQIEKERLRHLDMEHERLQLE----------------KERLQIEREKL--R 265
           E L+ +   LQ   E+LR ++ E   +QL                 +++LQ+E ++L   
Sbjct: 214 EELKEKNAELQ---EKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270

Query: 266 LQIVNSEKPSL--ENEL------GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317
           LQ V+++  +   ENEL       Q EK   Q + I+ ++ K+  + L++ +   +  + 
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR- 329

Query: 318 ESEKLQIEKERLQVEKDRLRIQKE 341
           + EK+  ++E+++ ++D++  Q+E
Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEE 353



 Score = 32.3 bits (72), Expect = 0.64
 Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 12/152 (7%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDS-RRENELPDFPHIDEFFTLNSTPSRSAY 198
           E K++EEE   Q  E +I+ +EE +      + R+E  L     I E            +
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMW 513

Query: 199 DEPHLLVNIEK------QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERL-- 250
           ++   +   E+      +K+  ++ RL  + E++Q ++ RLQ  +ERL  L  + E L  
Sbjct: 514 EQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573

Query: 251 ---QLEKERLQIEREKLRLQIVNSEKPSLENE 279
              +   +RL      L++++ + E  SL+ +
Sbjct: 574 AGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 45/205 (21%), Positives = 99/205 (48%), Gaps = 4/205 (1%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E   +EE+ + +   +EIEE E +  S   +  R+ E       ++       P R +  
Sbjct: 145 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 204

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD--MEHERLQLE-KER 256
           E  + V +E++  E ++  + +  +  Q+  E  + E+ER +  D    HE+++ E KER
Sbjct: 205 ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKER 264

Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316
            + ER +L  +     K   + ++   E++ ++ ++    + +  RE  + E+ R +  +
Sbjct: 265 AEAERARLEAEERERIKAEQDKKIAD-ERARIEAEEKAAAQERERREAEERERMREEEKR 323

Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341
              E+ +I++E  +  ++R RI++E
Sbjct: 324 AAEERQRIKEEEKRAAEERQRIKEE 348



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 54/234 (23%), Positives = 101/234 (43%), Gaps = 31/234 (13%)

Query: 130 DFRDAGGSLTEVKVEEEERDPQSPEFEI--------------EEEEEMLSSVIPDSRREN 175
           D+RDA  +  E K +EEE + +     I              E +EE +   + + +  +
Sbjct: 176 DWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISS 235

Query: 176 ELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRR-------LDIEAERLQV 228
           E P      E  +   +      +E       E+ +LE E+R          I  ER ++
Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARI 295

Query: 229 EKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLE--NELGQGEKS 286
           E E     +ER R    E ER++ E++R   ER++++      EK + E    + + EK 
Sbjct: 296 EAEEKAAAQERERREAEERERMREEEKRAAEERQRIK----EEEKRAAEERQRIKEEEKR 351

Query: 287 MLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQK 340
             +    E +++K E +R   E+ R +  + E  K++ +K   Q+E+ +  +Q+
Sbjct: 352 AAE----ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE 401



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 43/195 (22%), Positives = 95/195 (48%), Gaps = 17/195 (8%)

Query: 142 KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEP 201
           K+ +E    ++ E    +E E   +   +  RE E       +E   +     R+A  E 
Sbjct: 287 KIADERARIEAEEKAAAQERERREAEERERMREEEKRA---AEERQRIKEEEKRAA--EE 341

Query: 202 HLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIER 261
              +  E+++   E++R+  E +R   E++R + E+E    ++ +    QLE+++  ++ 
Sbjct: 342 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE 401

Query: 262 EKLRLQIVN--------SEKPSLENELGQGEKSMLQPQDIET-EKLKLERERLQLEKDRL 312
            K++ + V         +EK + E++L   + ++L+ Q  E   K++ +RE+LQ +K   
Sbjct: 402 TKIKGEKVEQKIEGKWVNEKKAQEDKL---QTAVLKKQGEEKGTKVQAKREKLQEDKPTF 458

Query: 313 QFLKFESEKLQIEKE 327
           +  + + EK++ +KE
Sbjct: 459 KKEEIKDEKIKKDKE 473



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 69/356 (19%), Positives = 140/356 (39%), Gaps = 56/356 (15%)

Query: 2   KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61
           ++ +R R+      E +  +KE  KR     + +    I   ++ A EE  +    + E 
Sbjct: 312 EERERMREEEKRAAEERQRIKEEEKR-----AAEERQRIKEEEKRAAEERQR----IKEE 362

Query: 62  EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLD-DSLTEEIDEKIGFRND 120
           E+R   E +R   +     K +  K N +L      +  + +  + + ++I+ K      
Sbjct: 363 EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK 422

Query: 121 ANFDWQNVADFRDAGGSL-TEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPD 179
           A  D    A  +  G    T+V+ + E+     P F+ EE ++    +  D   + E+  
Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKD--EKIKKDKEPKEEVKS 480

Query: 180 F-----------PHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEA-ERLQ 227
           F               EF T     + + +  P    +++ ++ E   +   +EA +RL+
Sbjct: 481 FMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ---VEAGKRLE 537

Query: 228 -VEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKS 286
            + + R + E E    L  + +   LE E L+ +RE+ R  +   E+   + E  +    
Sbjct: 538 ELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADR---- 593

Query: 287 MLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEG 342
                     KL+ E E+ +L             K +IE+ R +  + R ++ ++G
Sbjct: 594 ----------KLREEEEKRRL-------------KEEIERRRAEAAEKRQKMPEDG 626



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 65/286 (22%), Positives = 111/286 (38%), Gaps = 45/286 (15%)

Query: 7   KRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGEQRTG 66
           ++K N  ++E +  ++E   + E +  K     +N  K  A E+  Q      +GE++ G
Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK--AQEDKLQTAVLKKQGEEK-G 441

Query: 67  TEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEI-DEKIGFRNDANFDW 125
           T+V+          KR++++               D      EEI DEKI    +     
Sbjct: 442 TKVQA---------KREKLQ--------------EDKPTFKKEEIKDEKIKKDKEPK--- 475

Query: 126 QNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRE---NELPDFPH 182
           + V  F D     TEVK +  E        +++  E   S   P  R      E    P 
Sbjct: 476 EEVKSFMDRKKGFTEVKSQNGE----FMTHKLKHTENTFSR--PGGRASVDTKEAEGAPQ 529

Query: 183 IDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRH 242
           ++    L     R    E       EK K + ++  L++E  + + E+ R  +E+E  R 
Sbjct: 530 VEAGKRLEELRRRRGETESE---EFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRR 586

Query: 243 LDMEHERL---QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEK 285
              E +R    + EK RL+ E E+ R +     +   E+ L   +K
Sbjct: 587 KQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632


>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
          Length = 1173

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 53/225 (23%), Positives = 110/225 (48%), Gaps = 29/225 (12%)

Query: 126 QNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENE-LPDFPHID 184
           Q++ D ++        K++   RD Q  + +IEE+E +L +++P+       L D   ++
Sbjct: 598 QSIIDLKEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIME 657

Query: 185 EF-FTLNSTPSRSAYDEPHLL----------VNIEKQKLELEKRRLDIEAERLQVEKERL 233
            F   L     + A     L           VN EKQ+   ++ +LD  + ++++ ++ +
Sbjct: 658 RFQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQE---KQHKLDTVSSKIELNRKLI 714

Query: 234 QIEKERLRHL-----DMEHERLQLE---KERLQIEREKLRLQIVNSEKPSLENELGQGEK 285
           Q ++E+++HL     +++ E+LQ+    + R Q+E + + L   ++E  SL  E+ +  K
Sbjct: 715 QDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVEL---STEVQSLYREI-KDAK 770

Query: 286 SMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQ 330
             + P +   EK + E+E L  +K+     K   +KL   KE+++
Sbjct: 771 EQVSPLETTLEKFQQEKEELINKKNTSN--KIAQDKLNDIKEKVK 813



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 59/249 (23%), Positives = 108/249 (43%), Gaps = 50/249 (20%)

Query: 141 VKVEEEERDPQSPEFEIEEEEEMLSSVIP--------DSRRENELPDFPHIDEFFT---- 188
           VK  E E DP      ++E E  LS ++         DSR++    D   ++E       
Sbjct: 102 VKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQ 159

Query: 189 --------LNSTPSRSAYDEPHLLVNI--EKQKLELEKRRLDIEAERLQVEKERLQIE-- 236
                   L     R+  ++   LV+   E +KL  E R L+ E   L VE+ RLQ++  
Sbjct: 160 GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQAD 219

Query: 237 --KERLRHLDMEHERLQLEKERLQIEREKL-RLQIVNSEKPSLENELGQ----------- 282
             +E +R  D   + L  + E    ER      QI N  K   E + G+           
Sbjct: 220 RHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDF 279

Query: 283 GEKSMLQPQDIETEK---------LKLERERLQLEKDRLQFLKFESEKLQIEKER-LQVE 332
            EK  L+ + I+  +         ++L+ E L  +++ L+ +K+E ++L+   +R L+++
Sbjct: 280 AEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELD 339

Query: 333 KDRLRIQKE 341
           ++ ++ ++E
Sbjct: 340 QELIKAERE 348



 Score = 35.8 bits (81), Expect = 0.058
 Identities = 29/143 (20%), Positives = 73/143 (51%), Gaps = 7/143 (4%)

Query: 201 PHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERLQLEKERL 257
           P L   ++    ++++ + DIE +   +     + E  ++   D   ME  +++L+    
Sbjct: 609 PELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVER 668

Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317
           +I ++  +LQ ++ ++     ++ Q ++      D  + K++L R+ +Q +++++Q LK 
Sbjct: 669 KIAQQAAKLQGIDLDRTV--QQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKS 726

Query: 318 ESEKLQIEKERLQVEKDRLRIQK 340
            + +L+ EK  LQ+  +  R Q+
Sbjct: 727 TTNELKSEK--LQISTNLQRRQQ 747



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 4/71 (5%)

Query: 263 KLRLQIVNSEKPSLEN---ELGQGEKSMLQPQDIETEKLKLERERLQLEKD-RLQFLKFE 318
           +L+ +I++ ++  L+N   EL Q E S  +  +++ E +K ERE  + EK+  ++ LK E
Sbjct: 305 ELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKME 364

Query: 319 SEKLQIEKERL 329
              LQ EK  L
Sbjct: 365 VISLQNEKADL 375


>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
          Length = 1312

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 53/225 (23%), Positives = 110/225 (48%), Gaps = 29/225 (12%)

Query: 126 QNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENE-LPDFPHID 184
           Q++ D ++        K++   RD Q  + +IEE+E +L +++P+       L D   ++
Sbjct: 737 QSIIDLKEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIME 796

Query: 185 EF-FTLNSTPSRSAYDEPHLL----------VNIEKQKLELEKRRLDIEAERLQVEKERL 233
            F   L     + A     L           VN EKQ+   ++ +LD  + ++++ ++ +
Sbjct: 797 RFQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQE---KQHKLDTVSSKIELNRKLI 853

Query: 234 QIEKERLRHL-----DMEHERLQLE---KERLQIEREKLRLQIVNSEKPSLENELGQGEK 285
           Q ++E+++HL     +++ E+LQ+    + R Q+E + + L   ++E  SL  E+ +  K
Sbjct: 854 QDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVEL---STEVQSLYREI-KDAK 909

Query: 286 SMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQ 330
             + P +   EK + E+E L  +K+     K   +KL   KE+++
Sbjct: 910 EQVSPLETTLEKFQQEKEELINKKNTSN--KIAQDKLNDIKEKVK 952



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 59/249 (23%), Positives = 108/249 (43%), Gaps = 50/249 (20%)

Query: 141 VKVEEEERDPQSPEFEIEEEEEMLSSVIP--------DSRRENELPDFPHIDEFFT---- 188
           VK  E E DP      ++E E  LS ++         DSR++    D   ++E       
Sbjct: 241 VKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQ 298

Query: 189 --------LNSTPSRSAYDEPHLLVNI--EKQKLELEKRRLDIEAERLQVEKERLQIE-- 236
                   L     R+  ++   LV+   E +KL  E R L+ E   L VE+ RLQ++  
Sbjct: 299 GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQAD 358

Query: 237 --KERLRHLDMEHERLQLEKERLQIEREKL-RLQIVNSEKPSLENELGQ----------- 282
             +E +R  D   + L  + E    ER      QI N  K   E + G+           
Sbjct: 359 RHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDF 418

Query: 283 GEKSMLQPQDIETEK---------LKLERERLQLEKDRLQFLKFESEKLQIEKER-LQVE 332
            EK  L+ + I+  +         ++L+ E L  +++ L+ +K+E ++L+   +R L+++
Sbjct: 419 AEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELD 478

Query: 333 KDRLRIQKE 341
           ++ ++ ++E
Sbjct: 479 QELIKAERE 487



 Score = 35.8 bits (81), Expect = 0.058
 Identities = 29/143 (20%), Positives = 73/143 (51%), Gaps = 7/143 (4%)

Query: 201 PHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERLQLEKERL 257
           P L   ++    ++++ + DIE +   +     + E  ++   D   ME  +++L+    
Sbjct: 748 PELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVER 807

Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317
           +I ++  +LQ ++ ++     ++ Q ++      D  + K++L R+ +Q +++++Q LK 
Sbjct: 808 KIAQQAAKLQGIDLDRTV--QQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKS 865

Query: 318 ESEKLQIEKERLQVEKDRLRIQK 340
            + +L+ EK  LQ+  +  R Q+
Sbjct: 866 TTNELKSEK--LQISTNLQRRQQ 886



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 4/71 (5%)

Query: 263 KLRLQIVNSEKPSLEN---ELGQGEKSMLQPQDIETEKLKLERERLQLEKD-RLQFLKFE 318
           +L+ +I++ ++  L+N   EL Q E S  +  +++ E +K ERE  + EK+  ++ LK E
Sbjct: 444 ELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKME 503

Query: 319 SEKLQIEKERL 329
              LQ EK  L
Sbjct: 504 VISLQNEKADL 514


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 51/202 (25%), Positives = 103/202 (50%), Gaps = 21/202 (10%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K+ EEER  +  E ++ EEEEM+        RE E      + E            ++
Sbjct: 582 EEKMREEER-MREREKKMREEEEMM--------REQE----EKMQEQEEKMQEQEEKMWE 628

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259
           +   +   E++  E E++    E E    E++RL  +KE+L     EHE++Q E+E++Q 
Sbjct: 629 QEEKMQEQEEKMWEQEEKMW--EQEEKMWEQQRLPEQKEKL----WEHEKMQ-EQEKMQE 681

Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFES 319
           + EK+  Q    EK + E E    ++  ++ ++   E+ K  RE  ++ +++ + ++ + 
Sbjct: 682 QEEKIWEQ-EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740

Query: 320 EKLQIEKERLQVEKDRLRIQKE 341
           EK+Q ++E +  +++++  Q+E
Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEE 762



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 49/207 (23%), Positives = 106/207 (51%), Gaps = 27/207 (13%)

Query: 142 KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEP 201
           K++E+E      E +I ++EEM        R+E        + E         +  +D+ 
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564

Query: 202 HLLVNIEKQKLELEKRRLD-----IEAERLQVEKERLQIEKERLRHLDMEHERLQLEKER 256
                +EK+  E EK+  D      E ER++  +++++ E+E +R    + E++Q ++E+
Sbjct: 565 E---RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE---QEEKMQEQEEK 618

Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQD--IETEKLKLERERLQLEKDRLQF 314
           +Q + EK+  Q         E ++ + E+ M + ++   E E+   E++RL  +K++L  
Sbjct: 619 MQEQEEKMWEQ---------EEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL-- 667

Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341
             +E EK+Q E+E++Q +++++  Q++
Sbjct: 668 --WEHEKMQ-EQEKMQEQEEKIWEQEK 691



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 48/205 (23%), Positives = 104/205 (50%), Gaps = 15/205 (7%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K++E+E   Q  E ++ E+EE +     +   E E   +   ++ +     P +    
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQ-EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667

Query: 200 EPHLLVNIEKQKLELEKRRLDIEA-ERLQVEKERLQIEKERLRHLDM--EHERLQLEKER 256
             H  +  +++  E E++  + E  E+   E+E+   ++E++R  +   E E+   E+E 
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727

Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316
           +  E+E+ ++Q    +    E E+ + E+ M      E E+   E++RL  +K++L    
Sbjct: 728 MMREQEE-KMQEQEEKMQEQEEEMWEQEEKMW-----EQEEKMWEQQRLPEQKEKL---- 777

Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341
           +E EK+Q E+E++  +++++R Q+E
Sbjct: 778 WEHEKMQ-EQEKIWEQEEKMRDQEE 801



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 57/249 (22%), Positives = 124/249 (49%), Gaps = 32/249 (12%)

Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169
           E +EK+  + +  ++ Q + + ++    L E +  +E+   Q  E +I E+E+M      
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKE---KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT-- 696

Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEA------ 223
              +E +  D   + E  ++     +   +E  +    EK + + EK +   E       
Sbjct: 697 -QEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755

Query: 224 -----ERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLEN 278
                E    E++RL  +KE+L     EHE++Q E+E++  + EK+R Q    EK   + 
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKL----WEHEKMQ-EQEKIWEQEEKMRDQ---EEKMRGQE 807

Query: 279 ELGQGEKSMLQPQDI----ETEKLKLERERLQLEKDRL--QFLKFESEKLQIEKERLQVE 332
           E  +G++  ++ Q+     + EK+  + E++  +++++  Q  K E EK+Q ++E+++ +
Sbjct: 808 EKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME-EKMQGQEEKMREQ 866

Query: 333 KDRLRIQKE 341
           ++++R Q+E
Sbjct: 867 EEKMRGQEE 875



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 48/227 (21%), Positives = 110/227 (48%), Gaps = 32/227 (14%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K+ E+E      E  + E+E+ L     + R + EL +     +              
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMR 365

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERL--QLEK 254
           E    +  ++++L  +++++  + ++++ ++ER+  + ERLR  +    E E++  Q+EK
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425

Query: 255 ----ERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI----------------E 294
               +++Q + +K R Q    EK   E  + + EK M + ++                 E
Sbjct: 426 MREEKKMQEQEKKTRDQ---EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482

Query: 295 TEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
            E+ + +++RL  +K++L    +E EK+Q ++E++  +++++R Q+E
Sbjct: 483 QEEKEWQQQRLPEQKEKL----WEQEKMQEQEEKIWEQEEKIRDQEE 525



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 52/271 (19%), Positives = 125/271 (46%), Gaps = 60/271 (22%)

Query: 109 EEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVI 168
           E + EK     +    W+ V   R+      E K++E+E+  +  E +++EEE +     
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMRE------EKKMQEQEKKTRDQEEKMQEEERI----- 452

Query: 169 PDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEK----QKLELEKRRLDIEAE 224
               RE ++ +     E  T+     +    E ++    EK    Q+L  +K +L  E E
Sbjct: 453 --REREKKMRE-----EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL-WEQE 504

Query: 225 RLQVEKERLQIEKERLRHLD---------MEHERLQLEKERLQIEREKLRLQIVN----- 270
           ++Q ++E++  ++E++R  +            E+++ +++++  + EK+R Q        
Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564

Query: 271 -----------------SEKPSLENELGQGEKSMLQPQDI---ETEKLKLERERLQLEKD 310
                             EK   E  + + EK M + +++   + EK++ + E++Q +++
Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624

Query: 311 RLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           ++     + EK+Q ++E++  +++++  Q+E
Sbjct: 625 KMWE---QEEKMQEQEEKMWEQEEKMWEQEE 652



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 42/209 (20%), Positives = 95/209 (45%), Gaps = 35/209 (16%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K +E+E+     E ++ EEE M         RE E                       
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERM---------RERE-------------------KKMR 599

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERLQLEKER 256
           E   ++  +++K++ ++ ++  + E++  ++E++Q ++E++   +    E E    E++R
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659

Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316
           L  ++EKL       EK   + ++ + E+ + + + +E +  + E++    EK R +   
Sbjct: 660 LPEQKEKLW----EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715

Query: 317 FESEKLQIEKERLQVEKDRLRIQKEGHLQ 345
            E EK   E+E +  E++    ++E  +Q
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQ 744



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 36/136 (26%), Positives = 88/136 (64%), Gaps = 14/136 (10%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267
           E+Q+L  +K +L  E E++Q E+E++  ++E++R    + E+++ ++E+++ + EK+R Q
Sbjct: 766 EQQRLPEQKEKL-WEHEKMQ-EQEKIWEQEEKMRD---QEEKMRGQEEKMRGQEEKMRGQ 820

Query: 268 IVNSEKPSLENEL--GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIE 325
               EK   + E   GQ EK   Q + +  ++ K+E E++Q +++++   + + EK++ +
Sbjct: 821 ---EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME-EKMQGQEEKM---REQEEKMRGQ 873

Query: 326 KERLQVEKDRLRIQKE 341
           +E+++ +++++R Q+E
Sbjct: 874 EEKMREQEEKMRGQEE 889



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 43/207 (20%), Positives = 108/207 (52%), Gaps = 9/207 (4%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDF--PHIDEFFTLNSTPSRSA 197
           E+K +  E   + P  E E+ E  L+  + + +R+ E   F  P + +  TL     R  
Sbjct: 222 ELKKKNAELQEKLPLAESEKSEIQLN--VKELKRKLERAKFLLPQV-QTNTLQEEMWRQE 278

Query: 198 YD--EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLE-K 254
            +  E    +  +++K+  ++ RL  +  +++ ++E++  +++RLR  + E    + E +
Sbjct: 279 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338

Query: 255 ERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQF 314
           E+ ++  ++ ++Q    +    E ++ + E+ M + ++   E+ K  RE+ Q  +D+ + 
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398

Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341
           +  + E+L+ ++ER++ E++++  Q E
Sbjct: 399 MWEQDERLREKEERMR-EQEKMWEQVE 424


>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
           subfamily a-like [Homo sapiens]
          Length = 432

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 52/140 (37%), Positives = 80/140 (57%), Gaps = 24/140 (17%)

Query: 209 KQKLELEKRRLDIEAERLQV-------EKERLQIEKERLRHLDMEHERLQLEKERLQIER 261
           +++LE   R+L  E E  Q+       ++ERL+ ++ERLR    + ERL  ++ERL  + 
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLRE---QEERLCEQEERLCEQE 226

Query: 262 EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321
           E+LR Q    E+   E E   G++ +L+    E EKL L++ER Q E++RL     E E+
Sbjct: 227 ERLREQ----EERLCEQEKLPGQERLLE----EVEKL-LKQERRQEEQERL----LERER 273

Query: 322 LQIEKERLQVEKDRLRIQKE 341
           L  E E L +E++RLR Q E
Sbjct: 274 LLDEVEEL-LEQERLRQQDE 292



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 43/143 (30%), Positives = 71/143 (49%), Gaps = 24/143 (16%)

Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIERE 262
           LL   ++++L  ++ RL  + ERL  ++ERL  ++ERLR           E+E    E+E
Sbjct: 192 LLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLR-----------EQEERLCEQE 240

Query: 263 KLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322
           KL         P  E  L + EK + Q +  E ++  LERERL  E + L     E E+L
Sbjct: 241 KL---------PGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEEL----LEQERL 287

Query: 323 QIEKERLQVEKDRLRIQKEGHLQ 345
           + + ERL  ++    +++   L+
Sbjct: 288 RQQDERLWQQETLRELERLRELE 310


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 65/325 (20%), Positives = 141/325 (43%), Gaps = 58/325 (17%)

Query: 21  LKEITKRKEVIFSKQLNTTIN----VMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDW 76
           ++E+TK ++ +  +    TI       K    +E  Q V +     Q    E+KR+    
Sbjct: 183 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 242

Query: 77  RALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGG 136
           + L+ +++++A    +G      S+ L   + E            N  W  +   ++   
Sbjct: 243 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE------------NELWNRLNQQQEEKM 290

Query: 137 SLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRS 196
              E K++E E   Q  E +I E+EE +       RR+ E+                   
Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKM-------RRQEEM------------------- 324

Query: 197 AYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKER 256
            +++   +   E+   E E++  ++E +  + EK R Q EK +      E E+ Q ++ +
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384

Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316
           +  + EK+R Q           E  + ++ M+Q Q+   EK+  + E++  +++ +Q   
Sbjct: 385 MWRQEEKIREQ----------EEKIREQEEMMQEQE---EKMGEQEEKMWEQEEEMQE-- 429

Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341
            + EK++ ++E+++ ++ ++R Q+E
Sbjct: 430 -QEEKMRRQEEKIREQEKKIREQEE 453



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 41/206 (19%), Positives = 109/206 (52%), Gaps = 26/206 (12%)

Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199
           E K+  +E   +  E +I E+EEM+     +   E E   +   +E              
Sbjct: 382 EAKMWRQEEKIREQEEKIREQEEMMQEQ-EEKMGEQEEKMWEQEEEM------------Q 428

Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD----MEHERLQLEKE 255
           E    +  +++K+  +++++  + E+++ ++E +Q ++E++   +     +  ++Q ++E
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488

Query: 256 RLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFL 315
           +++ + EK+R Q    +K   + E  + ++ M+Q Q+   EK+  + E++  +++++Q  
Sbjct: 489 KMRRQEEKIREQ---EKKIREQEEKIREQEEMMQEQE---EKMWEQEEKMCEQEEKMQE- 541

Query: 316 KFESEKLQIEKERLQVEKDRLRIQKE 341
             + EK++ ++E+++ ++ RLR Q+E
Sbjct: 542 --QEEKMRRQEEKMREQEVRLRQQEE 565



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 45/235 (19%), Positives = 113/235 (48%), Gaps = 20/235 (8%)

Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169
           E +EK+  R      W+     R+    + E +   E+ + +  E +I E+E+       
Sbjct: 327 EKEEKM--RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384

Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAE-RLQV 228
             R+E ++ +                   ++  ++   E++  E E++  + E E + Q 
Sbjct: 385 MWRQEEKIRE-------------QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431

Query: 229 EKERLQIEK--ERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKS 286
           EK R Q EK  E+ + +  + E+++ ++E +Q + EK+  Q    +    E ++ + E+ 
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ--EGKMCEQEAKMQEQEEK 489

Query: 287 MLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341
           M + ++   E+ K  RE+ +  +++ + ++ + EK+  ++E++  ++++++ Q+E
Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 544



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 47/272 (17%), Positives = 119/272 (43%), Gaps = 33/272 (12%)

Query: 2   KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61
           ++++R+ +  +  +E     +E+   KE    +         K    EE  Q    + E 
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375

Query: 62  EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDA 121
           E+R   E K     WR   K +  +  I+              + + +E +EK+G + + 
Sbjct: 376 EKRQEQEAKM----WRQEEKIREQEEKIRE------------QEEMMQEQEEKMGEQEEK 419

Query: 122 NFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP 181
            ++ +     ++      E K+ E+E+  +  E +I E+EEM+        +E ++ +  
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM------QEQEEKMGEQE 473

Query: 182 HIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL- 240
                         +   E    +  +++K+  +++++  + E+++ ++E +Q ++E++ 
Sbjct: 474 G-------KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 526

Query: 241 ---RHLDMEHERLQLEKERLQIEREKLRLQIV 269
                +  + E++Q ++E+++ + EK+R Q V
Sbjct: 527 EQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558


>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
          Length = 432

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 52/140 (37%), Positives = 80/140 (57%), Gaps = 24/140 (17%)

Query: 209 KQKLELEKRRLDIEAERLQV-------EKERLQIEKERLRHLDMEHERLQLEKERLQIER 261
           +++LE   R+L  E E  Q+       ++ERL+ ++ERLR    + ERL  ++ERL  + 
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLRE---QEERLCEQEERLCEQE 226

Query: 262 EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321
           E+LR Q    E+   E E   G++ +L+    E EKL L++ER Q E++RL     E E+
Sbjct: 227 ERLREQ----EERLCEQEKLPGQERLLE----EVEKL-LKQERRQEEQERL----LERER 273

Query: 322 LQIEKERLQVEKDRLRIQKE 341
           L  E E L +E++RLR Q E
Sbjct: 274 LLDEVEEL-LEQERLRQQDE 292



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 43/143 (30%), Positives = 71/143 (49%), Gaps = 24/143 (16%)

Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIERE 262
           LL   ++++L  ++ RL  + ERL  ++ERL  ++ERLR           E+E    E+E
Sbjct: 192 LLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLR-----------EQEERLCEQE 240

Query: 263 KLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322
           KL         P  E  L + EK + Q +  E ++  LERERL  E + L     E E+L
Sbjct: 241 KL---------PGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEEL----LEQERL 287

Query: 323 QIEKERLQVEKDRLRIQKEGHLQ 345
           + + ERL  ++    +++   L+
Sbjct: 288 RQQDERLWQQETLRELERLRELE 310


>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 432

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 52/140 (37%), Positives = 79/140 (56%), Gaps = 24/140 (17%)

Query: 209 KQKLELEKRRLDIEAERLQV-------EKERLQIEKERLRHLDMEHERLQLEKERLQIER 261
           +++LE   R+L  E E  Q+       ++ERL+ ++ERLR    + ERL  ++ERL  + 
Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLRE---QEERLHEQEERLCEQE 226

Query: 262 EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321
           E+L  Q    E+   E E   G++ +L+    E EKL LE+ER Q E++RL     E E+
Sbjct: 227 ERLCEQ----EERLCEQEKLPGQERLLE----EVEKL-LEQERRQEEQERL----LERER 273

Query: 322 LQIEKERLQVEKDRLRIQKE 341
           L  E E L +E++RLR Q E
Sbjct: 274 LLDEVEEL-LEQERLRQQDE 292



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 24/143 (16%)

Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIERE 262
           LL   ++++L  ++ RL  + ERL  ++ERL  ++ERL            E+E    E+E
Sbjct: 192 LLNRRQEERLREQEERLREQEERLHEQEERLCEQEERL-----------CEQEERLCEQE 240

Query: 263 KLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322
           KL         P  E  L + EK + Q +  E ++  LERERL  E + L     E E+L
Sbjct: 241 KL---------PGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEEL----LEQERL 287

Query: 323 QIEKERLQVEKDRLRIQKEGHLQ 345
           + + ERL  ++    +++   L+
Sbjct: 288 RQQDERLWQQETLRELERLRELE 310



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 17/152 (11%)

Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD--------MEHERLQLEKERLQI 259
           ++++L  ++ RL  + ERL  ++ERL  ++ERL   +        +E     LE+ER Q 
Sbjct: 204 QEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQE 263

Query: 260 EREKL--RLQIVNSEKPSLENE-LGQGEKSMLQPQDI-ETEKLKLERERLQLEKDRLQFL 315
           E+E+L  R ++++  +  LE E L Q ++ + Q + + E E+L+     L+L  + L   
Sbjct: 264 EQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQ 323

Query: 316 KFES----EKLQIE-KERLQVEKDRLRIQKEG 342
           + E     E+L  E K  LQ+E+    ++K G
Sbjct: 324 RAEPRSGFEELNNENKSTLQLEQQVKELEKSG 355


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,934,926
Number of Sequences: 37866
Number of extensions: 650332
Number of successful extensions: 11259
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 253
Number of HSP's successfully gapped in prelim test: 863
Number of HSP's that attempted gapping in prelim test: 4632
Number of HSP's gapped (non-prelim): 3918
length of query: 345
length of database: 18,247,518
effective HSP length: 103
effective length of query: 242
effective length of database: 14,347,320
effective search space: 3472051440
effective search space used: 3472051440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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