BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|58761537 hypothetical protein LOC84437 [Homo sapiens] (345 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|58761537 hypothetical protein LOC84437 [Homo sapiens] 674 0.0 gi|239748997 PREDICTED: hypothetical protein XP_002346878 [Homo ... 70 2e-12 gi|239743019 PREDICTED: hypothetical protein XP_002342720 [Homo ... 70 2e-12 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 66 5e-11 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 66 5e-11 gi|62244004 modulator of estrogen induced transcription isoform ... 64 3e-10 gi|63176611 modulator of estrogen induced transcription isoform ... 64 3e-10 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 62 8e-10 gi|56549694 enabled homolog isoform a [Homo sapiens] 62 1e-09 gi|39930375 enabled homolog isoform b [Homo sapiens] 62 1e-09 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 61 1e-09 gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 61 2e-09 gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 60 3e-09 gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 60 3e-09 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 5e-09 gi|148746195 trichohyalin [Homo sapiens] 59 8e-09 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 58 1e-08 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 57 2e-08 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 57 2e-08 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 57 2e-08 gi|7661936 scaffold attachment factor B2 [Homo sapiens] 56 4e-08 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 55 7e-08 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 55 7e-08 gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 54 2e-07 gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 54 2e-07 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 2e-07 gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 54 2e-07 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 54 2e-07 gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 54 2e-07 gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 54 2e-07 >gi|58761537 hypothetical protein LOC84437 [Homo sapiens] Length = 345 Score = 674 bits (1740), Expect = 0.0 Identities = 345/345 (100%), Positives = 345/345 (100%) Query: 1 MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGE 60 MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGE Sbjct: 1 MKQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGE 60 Query: 61 GEQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRND 120 GEQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRND Sbjct: 61 GEQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRND 120 Query: 121 ANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDF 180 ANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDF Sbjct: 121 ANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDF 180 Query: 181 PHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL 240 PHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL Sbjct: 181 PHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL 240 Query: 241 RHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKL 300 RHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKL Sbjct: 241 RHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKL 300 Query: 301 ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345 ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ Sbjct: 301 ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345 >gi|239748997 PREDICTED: hypothetical protein XP_002346878 [Homo sapiens] Length = 297 Score = 70.5 bits (171), Expect = 2e-12 Identities = 65/219 (29%), Positives = 105/219 (47%), Gaps = 29/219 (13%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203 + + + PQ P + EE R +P L S S+S+ +P + Sbjct: 11 DRQHQLPQQPGSSPPDPEEQRELEPLIRTRRKNIPAPSRFQGLSLLPSCDSKSSASKPQM 70 Query: 204 -----------LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQL 252 + +E+ L++E++ L +E LQVEK+ LQ+E+ R L +E LQ+ Sbjct: 71 EEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEE---RSLQVEERSLQV 127 Query: 253 EKERLQIEREKLRLQIVNSEKPSLENELG--QGEKSMLQPQDIETEKLKLERERLQLEKD 310 E++ LQ+E L++ E+ SL+ E G Q E+ LQ +E L++E LQ+E+ Sbjct: 128 EEKSLQVEERSLQV-----EERSLQVEEGSLQVEEGSLQ---VEEGDLQVEEGGLQVEEG 179 Query: 311 RLQF----LKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345 LQ L E L +E+ LQVE+ L ++ EG LQ Sbjct: 180 SLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVE-EGGLQ 217 Score = 64.3 bits (155), Expect = 2e-10 Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 28/163 (17%) Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKL 264 + +EK+ L++E+R L +E LQVE++ LQ+E+ R L +E LQ+E+ LQ+E L Sbjct: 104 LQVEKKSLQVEERSLQVEERSLQVEEKSLQVEE---RSLQVEERSLQVEEGSLQVEEGSL 160 Query: 265 RLQ--IVNSEKPSLENELG--QGEKSMLQPQD----IETEKLKLERERLQLEKDRLQF-- 314 +++ + E+ L+ E G Q E+ L ++ +E L++E L +E+ LQ Sbjct: 161 QVEEGDLQVEEGGLQVEEGSLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEE 220 Query: 315 ---------------LKFESEKLQIEKERLQVEKDRLRIQKEG 342 L+ E LQ+E+ LQVEK L+++K G Sbjct: 221 GACRWRRGAADGGGGLQMEEGGLQVEEGGLQVEKGGLQVEKGG 263 Score = 57.0 bits (136), Expect = 2e-08 Identities = 49/165 (29%), Positives = 86/165 (52%), Gaps = 29/165 (17%) Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLR----HLDMEHERLQLEKERLQIE 260 + +E++ L++E+R L +E LQVE+ LQ+E+ L+ L +E LQ+E+ LQ+E Sbjct: 125 LQVEEKSLQVEERSLQVEERSLQVEEGSLQVEEGSLQVEEGDLQVEEGGLQVEEGSLQVE 184 Query: 261 REKLRLQI--VNSEKPSLENELG--QGEKSMLQPQD-----------------IETEKLK 299 L ++ ++ E+ L+ E G E+ LQ ++ +E L+ Sbjct: 185 EGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEEGACRWRRGAADGGGGLQMEEGGLQ 244 Query: 300 LERERLQLEKDRLQF----LKFESEKLQIEKERLQVEKDRLRIQK 340 +E LQ+EK LQ L+ E LQ+E+ LQVE+ L++++ Sbjct: 245 VEEGGLQVEKGGLQVEKGGLQVEERDLQVEEGSLQVEERSLQVEE 289 Score = 32.7 bits (73), Expect = 0.49 Identities = 21/54 (38%), Positives = 34/54 (62%), Gaps = 4/54 (7%) Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQ 258 + +E+ L++EK L +E LQVE+ LQ+E+ L+ +E LQ+E ER+Q Sbjct: 243 LQVEEGGLQVEKGGLQVEKGGLQVEERDLQVEEGSLQ---VEERSLQVE-ERVQ 292 >gi|239743019 PREDICTED: hypothetical protein XP_002342720 [Homo sapiens] Length = 487 Score = 70.5 bits (171), Expect = 2e-12 Identities = 65/219 (29%), Positives = 105/219 (47%), Gaps = 29/219 (13%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203 + + + PQ P + EE R +P L S S+S+ +P + Sbjct: 201 DRQHQLPQQPGSSPPDPEEQRELEPLIRTRRKNIPAPSRFQGLSLLPSCDSKSSASKPQM 260 Query: 204 -----------LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQL 252 + +E+ L++E++ L +E LQVEK+ LQ+E+ R L +E LQ+ Sbjct: 261 EEERSLQVEEGSLQVEEGSLQVEEKSLQVEEGSLQVEKKSLQVEE---RSLQVEERSLQV 317 Query: 253 EKERLQIEREKLRLQIVNSEKPSLENELG--QGEKSMLQPQDIETEKLKLERERLQLEKD 310 E++ LQ+E L++ E+ SL+ E G Q E+ LQ +E L++E LQ+E+ Sbjct: 318 EEKSLQVEERSLQV-----EERSLQVEEGSLQVEEGSLQ---VEEGDLQVEEGGLQVEEG 369 Query: 311 RLQF----LKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345 LQ L E L +E+ LQVE+ L ++ EG LQ Sbjct: 370 SLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVE-EGGLQ 407 Score = 64.3 bits (155), Expect = 2e-10 Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 28/163 (17%) Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKL 264 + +EK+ L++E+R L +E LQVE++ LQ+E+ R L +E LQ+E+ LQ+E L Sbjct: 294 LQVEKKSLQVEERSLQVEERSLQVEEKSLQVEE---RSLQVEERSLQVEEGSLQVEEGSL 350 Query: 265 RLQ--IVNSEKPSLENELG--QGEKSMLQPQD----IETEKLKLERERLQLEKDRLQF-- 314 +++ + E+ L+ E G Q E+ L ++ +E L++E L +E+ LQ Sbjct: 351 QVEEGDLQVEEGGLQVEEGSLQVEEGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEE 410 Query: 315 ---------------LKFESEKLQIEKERLQVEKDRLRIQKEG 342 L+ E LQ+E+ LQVEK L+++K G Sbjct: 411 GACRWRRGAADGGGGLQMEEGGLQVEEGGLQVEKGGLQVEKGG 453 Score = 57.0 bits (136), Expect = 2e-08 Identities = 49/165 (29%), Positives = 86/165 (52%), Gaps = 29/165 (17%) Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLR----HLDMEHERLQLEKERLQIE 260 + +E++ L++E+R L +E LQVE+ LQ+E+ L+ L +E LQ+E+ LQ+E Sbjct: 315 LQVEEKSLQVEERSLQVEERSLQVEEGSLQVEEGSLQVEEGDLQVEEGGLQVEEGSLQVE 374 Query: 261 REKLRLQI--VNSEKPSLENELG--QGEKSMLQPQD-----------------IETEKLK 299 L ++ ++ E+ L+ E G E+ LQ ++ +E L+ Sbjct: 375 EGSLHVEEGDLHVEEGGLQVEEGTLHVEEGGLQVEEGACRWRRGAADGGGGLQMEEGGLQ 434 Query: 300 LERERLQLEKDRLQF----LKFESEKLQIEKERLQVEKDRLRIQK 340 +E LQ+EK LQ L+ E LQ+E+ LQVE+ L++++ Sbjct: 435 VEEGGLQVEKGGLQVEKGGLQVEERDLQVEEGSLQVEERSLQVEE 479 Score = 32.7 bits (73), Expect = 0.49 Identities = 21/54 (38%), Positives = 34/54 (62%), Gaps = 4/54 (7%) Query: 205 VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQ 258 + +E+ L++EK L +E LQVE+ LQ+E+ L+ +E LQ+E ER+Q Sbjct: 433 LQVEEGGLQVEKGGLQVEKGGLQVEERDLQVEEGSLQ---VEERSLQVE-ERVQ 482 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 65.9 bits (159), Expect = 5e-11 Identities = 82/359 (22%), Positives = 165/359 (45%), Gaps = 32/359 (8%) Query: 2 KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61 K LK ++++ ++ + L EI + K+ + + Q N + ++MK A ++ + + + E Sbjct: 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQ-NLSKDLMKEKA--QLEKTIETLREN 548 Query: 62 EQRTGT--EVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRN 119 +R E + +L+ R+R + + + + L +S+ E + Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608 Query: 120 DANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIE--------EEEEMLSSVIPDS 171 + + + +++ G E++ E + ++ + + E+ E L + Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 668 Query: 172 RRENE-----LPDFPHIDEFFTLNSTPSR-SAYDEPHLLV--NIEKQKL-ELEKRRLDIE 222 REN L F ++ F L S S DE +L + N+E K ++ +L +E Sbjct: 669 ERENRKLKKTLDSFKNLT--FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE 726 Query: 223 AERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQ 282 + L+ EKE+L+ E L+ + ERL++ + L IE ++L+ + NS K + E Sbjct: 727 NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLE--- 783 Query: 283 GEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 S LQ ++E + L+ E L++ RL+ L E E +E+E Q+EKD+ +++KE Sbjct: 784 ---SELQDLEMENQTLQKNLEELKISSKRLEQL--EKENKSLEQETSQLEKDKKQLEKE 837 Score = 58.5 bits (140), Expect = 8e-09 Identities = 89/368 (24%), Positives = 156/368 (42%), Gaps = 73/368 (19%) Query: 2 KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61 K+L+ ++ +E + L + K E++ K N I K A E+ Sbjct: 615 KELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQ----------- 663 Query: 62 EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDA 121 +E++R RK K F L S + ++S +E E + R Sbjct: 664 ---ENSELERE--------NRKLKKTLDSFKNLTFQLESLEKENSQLDE--ENLELR--- 707 Query: 122 NFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP 181 +NV + A + ++++E +E + S + ++++ E+L + + R + Sbjct: 708 ----RNVESLKCASMKMAQLQLENKELE--SEKEQLKKGLELLKASFKKTERLEV--SYQ 759 Query: 182 HID-EFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERL-QIEKER 239 +D E L T S L E Q LE+E + L E L++ +RL Q+EKE Sbjct: 760 GLDIENQRLQKTLENSNKKIQQL--ESELQDLEMENQTLQKNLEELKISSKRLEQLEKE- 816 Query: 240 LRHLDMEHERLQLEKERLQIEREKLRL----------------QIVNSEK--PSLENELG 281 + +E E QLEK++ Q+E+E RL +I N EK +L E+G Sbjct: 817 --NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIG 874 Query: 282 QGEKSMLQPQDIETEKLKLE-------------RERLQLEKDRLQFLKFESEKLQIEKER 328 ++S ++ +++E E +L RE L EK + Q + + EKL E E+ Sbjct: 875 IYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEK 934 Query: 329 LQVEKDRL 336 + + K+RL Sbjct: 935 IGLNKERL 942 Score = 50.1 bits (118), Expect = 3e-06 Identities = 79/368 (21%), Positives = 155/368 (42%), Gaps = 35/368 (9%) Query: 2 KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61 K K+ K N +++ Q +K+ T + + L + + CV + E Sbjct: 829 KDKKQLEKENKRLRQ-QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVR-LKEL 886 Query: 62 EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDA 121 E+ VKR +D + L+ + + KL ++DL+ LT E+ EKIG + Sbjct: 887 EKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM---NNDLE-KLTHEL-EKIGLNKER 941 Query: 122 NFDWQNVADFRDAGGSLTEVKVEE--------EERDPQSPEFEIEEE---EEMLSSVIPD 170 + D D+ L E K+E +E + E +EE + L + Sbjct: 942 LLHDEQSTD--DSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKT 999 Query: 171 SRRENELPDFPHIDEFFTLNSTP--------SRSAYDEPHLLVNIEKQKLELEKRRLDIE 222 ++ E +E +S P R + + L+ ++ + +E+E+ ++ Sbjct: 1000 VKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQ 1059 Query: 223 AERLQVEKERLQIEKE----RLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLEN 278 AE+ ++ + Q+E + + + L ++ + + L+++ ++ + +LQ+ NS S Sbjct: 1060 AEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQST 1119 Query: 279 EL-GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLR 337 L Q + ++Q +E E + +ER L K L + EKL++ ER E + L Sbjct: 1120 SLMNQNAQLLIQQSSLENENESVIKEREDL-KSLYDSLIKDHEKLELLHERQASEYESL- 1177 Query: 338 IQKEGHLQ 345 I K G L+ Sbjct: 1178 ISKHGTLK 1185 Score = 42.7 bits (99), Expect = 5e-04 Identities = 40/186 (21%), Positives = 85/186 (45%), Gaps = 17/186 (9%) Query: 157 IEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEK 216 I+E +E ++I S + L PH S+ ++S P + +Q L +E Sbjct: 201 IDERDEHSETIIELSEERDGLHFLPHA-------SSSAQSPCGSPGMKRTESRQHLSVE- 252 Query: 217 RRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSL 276 + + ++ + R ++E++ + LD + E E+++IE ++L+ + +N + Sbjct: 253 ----LADAKAKIRRLRQELEEKTEQLLDCKQEL-----EQMEIELKRLQQENMNLLSDAR 303 Query: 277 ENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336 + + E L+ + + +KL+ E R + ++F K E+L+ + + L K L Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTML 363 Query: 337 RIQKEG 342 Q EG Sbjct: 364 EDQLEG 369 Score = 42.7 bits (99), Expect = 5e-04 Identities = 44/171 (25%), Positives = 73/171 (42%), Gaps = 11/171 (6%) Query: 145 EEERDPQSPEFEIEEEEEMLSSVIPDSRRENELP---DFPHIDEFFTLNSTPSRSAYDEP 201 E ERD + E EE M + + L + I L+ P +S E Sbjct: 395 EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEV 454 Query: 202 HLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL--QI 259 + L + KLE+E + L E L+ + ++ ++ ++ E++RL + E L +I Sbjct: 455 NELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEI 514 Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKD 310 +EK LQ + L E Q EK+ IET + ER+ LE++ Sbjct: 515 VQEKQSLQNCQNLSKDLMKEKAQLEKT------IETLRENSERQIKILEQE 559 Score = 38.9 bits (89), Expect = 0.007 Identities = 39/157 (24%), Positives = 78/157 (49%), Gaps = 9/157 (5%) Query: 194 SRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLE 253 +R+ D+ H +EK+ L+L+ + D+E ER +++++++ E L+M ++ E Sbjct: 370 TRARSDKLH---ELEKENLQLKAKLHDMEMER-DMDRKKIEELMEENMTLEMAQKQSMDE 425 Query: 254 KERLQIEREKLRLQIVNSEKP--SLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDR 311 L E E++ SE P SL +E+ + S L ++E + L E L+ D Sbjct: 426 SLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDS 485 Query: 312 LQFLKFESEKLQIEKERLQVEKDRLR---IQKEGHLQ 345 ++ + K++ E +RL + + L +Q++ LQ Sbjct: 486 VEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522 Score = 36.6 bits (83), Expect = 0.034 Identities = 50/202 (24%), Positives = 91/202 (45%), Gaps = 14/202 (6%) Query: 147 ERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVN 206 E + +S E E+ + + S+I D + EL E+ +L S H + Sbjct: 1136 ENENESVIKEREDLKSLYDSLIKDHEKL-ELLHERQASEYESLIS--KHGTLKSAHKNLE 1192 Query: 207 IEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRL 266 +E + LE +L + +L+ ++ L++E+E++ + HE + E ++L E ++L Sbjct: 1193 VEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNH 1252 Query: 267 QIVNSEKPSLENELGQGE----KSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322 K E E+ Q + KS+L +E +L+ E +L K++ Q L S KL Sbjct: 1253 TYSQLLK---ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKL---KEQYQQLDITSTKL 1306 Query: 323 QIEKERLQVEKDRLRIQKEGHL 344 + E L K L ++ HL Sbjct: 1307 NNQCELLSQLKGNLE-EENRHL 1327 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 65.9 bits (159), Expect = 5e-11 Identities = 82/359 (22%), Positives = 165/359 (45%), Gaps = 32/359 (8%) Query: 2 KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61 K LK ++++ ++ + L EI + K+ + + Q N + ++MK A ++ + + + E Sbjct: 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQ-NLSKDLMKEKA--QLEKTIETLREN 548 Query: 62 EQRTGT--EVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRN 119 +R E + +L+ R+R + + + + L +S+ E + Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 608 Query: 120 DANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIE--------EEEEMLSSVIPDS 171 + + + +++ G E++ E + ++ + + E+ E L + Sbjct: 609 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 668 Query: 172 RRENE-----LPDFPHIDEFFTLNSTPSR-SAYDEPHLLV--NIEKQKL-ELEKRRLDIE 222 REN L F ++ F L S S DE +L + N+E K ++ +L +E Sbjct: 669 ERENRKLKKTLDSFKNLT--FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE 726 Query: 223 AERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQ 282 + L+ EKE+L+ E L+ + ERL++ + L IE ++L+ + NS K + E Sbjct: 727 NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLE--- 783 Query: 283 GEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 S LQ ++E + L+ E L++ RL+ L E E +E+E Q+EKD+ +++KE Sbjct: 784 ---SELQDLEMENQTLQKNLEELKISSKRLEQL--EKENKSLEQETSQLEKDKKQLEKE 837 Score = 58.5 bits (140), Expect = 8e-09 Identities = 89/368 (24%), Positives = 156/368 (42%), Gaps = 73/368 (19%) Query: 2 KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61 K+L+ ++ +E + L + K E++ K N I K A E+ Sbjct: 615 KELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQ----------- 663 Query: 62 EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDA 121 +E++R RK K F L S + ++S +E E + R Sbjct: 664 ---ENSELERE--------NRKLKKTLDSFKNLTFQLESLEKENSQLDE--ENLELR--- 707 Query: 122 NFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP 181 +NV + A + ++++E +E + S + ++++ E+L + + R + Sbjct: 708 ----RNVESLKCASMKMAQLQLENKELE--SEKEQLKKGLELLKASFKKTERLEV--SYQ 759 Query: 182 HID-EFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERL-QIEKER 239 +D E L T S L E Q LE+E + L E L++ +RL Q+EKE Sbjct: 760 GLDIENQRLQKTLENSNKKIQQL--ESELQDLEMENQTLQKNLEELKISSKRLEQLEKE- 816 Query: 240 LRHLDMEHERLQLEKERLQIEREKLRL----------------QIVNSEK--PSLENELG 281 + +E E QLEK++ Q+E+E RL +I N EK +L E+G Sbjct: 817 --NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIG 874 Query: 282 QGEKSMLQPQDIETEKLKLE-------------RERLQLEKDRLQFLKFESEKLQIEKER 328 ++S ++ +++E E +L RE L EK + Q + + EKL E E+ Sbjct: 875 IYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEK 934 Query: 329 LQVEKDRL 336 + + K+RL Sbjct: 935 IGLNKERL 942 Score = 48.9 bits (115), Expect = 7e-06 Identities = 43/193 (22%), Positives = 90/193 (46%), Gaps = 23/193 (11%) Query: 158 EEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKR 217 ++EE M+ S P S +N+ R + + L+ ++ + +E+E+ Sbjct: 1010 QDEERMVQSSPPISGEDNKW----------------ERESQETTRELLKVKDRLIEVERN 1053 Query: 218 RLDIEAERLQVEKERLQIEKE----RLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEK 273 ++AE+ ++ + Q+E + + + L ++ + + L+++ ++ + +LQ+ NS Sbjct: 1054 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1113 Query: 274 PSLENEL-GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVE 332 S L Q + ++Q +E E + +ER L K L + EKL++ ER E Sbjct: 1114 NSQSTSLMNQNAQLLIQQSSLENENESVIKEREDL-KSLYDSLIKDHEKLELLHERQASE 1172 Query: 333 KDRLRIQKEGHLQ 345 + L I K G L+ Sbjct: 1173 YESL-ISKHGTLK 1184 Score = 42.7 bits (99), Expect = 5e-04 Identities = 40/186 (21%), Positives = 85/186 (45%), Gaps = 17/186 (9%) Query: 157 IEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEK 216 I+E +E ++I S + L PH S+ ++S P + +Q L +E Sbjct: 201 IDERDEHSETIIELSEERDGLHFLPHA-------SSSAQSPCGSPGMKRTESRQHLSVE- 252 Query: 217 RRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSL 276 + + ++ + R ++E++ + LD + E E+++IE ++L+ + +N + Sbjct: 253 ----LADAKAKIRRLRQELEEKTEQLLDCKQEL-----EQMEIELKRLQQENMNLLSDAR 303 Query: 277 ENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336 + + E L+ + + +KL+ E R + ++F K E+L+ + + L K L Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTML 363 Query: 337 RIQKEG 342 Q EG Sbjct: 364 EDQLEG 369 Score = 42.7 bits (99), Expect = 5e-04 Identities = 44/171 (25%), Positives = 73/171 (42%), Gaps = 11/171 (6%) Query: 145 EEERDPQSPEFEIEEEEEMLSSVIPDSRRENELP---DFPHIDEFFTLNSTPSRSAYDEP 201 E ERD + E EE M + + L + I L+ P +S E Sbjct: 395 EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEV 454 Query: 202 HLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL--QI 259 + L + KLE+E + L E L+ + ++ ++ ++ E++RL + E L +I Sbjct: 455 NELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEI 514 Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKD 310 +EK LQ + L E Q EK+ IET + ER+ LE++ Sbjct: 515 VQEKQSLQNCQNLSKDLMKEKAQLEKT------IETLRENSERQIKILEQE 559 Score = 38.9 bits (89), Expect = 0.007 Identities = 39/157 (24%), Positives = 78/157 (49%), Gaps = 9/157 (5%) Query: 194 SRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLE 253 +R+ D+ H +EK+ L+L+ + D+E ER +++++++ E L+M ++ E Sbjct: 370 TRARSDKLH---ELEKENLQLKAKLHDMEMER-DMDRKKIEELMEENMTLEMAQKQSMDE 425 Query: 254 KERLQIEREKLRLQIVNSEKP--SLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDR 311 L E E++ SE P SL +E+ + S L ++E + L E L+ D Sbjct: 426 SLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDS 485 Query: 312 LQFLKFESEKLQIEKERLQVEKDRLR---IQKEGHLQ 345 ++ + K++ E +RL + + L +Q++ LQ Sbjct: 486 VEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522 Score = 37.4 bits (85), Expect = 0.020 Identities = 44/160 (27%), Positives = 74/160 (46%), Gaps = 33/160 (20%) Query: 213 ELEKRRLDIEAERLQVEKERLQIEKERLRH----LDMEHERLQLE-----KERLQIEREK 263 +L+ ++++ + E+L E E++ + KERL H D ++ L+ + K+ L+I+ EK Sbjct: 915 KLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEK 974 Query: 264 L-----RLQIVNSEKPSLENEL------------GQGEKSMLQPQ-DIETEKLKLERE-- 303 + RL+ + L EL Q E+ M+Q I E K ERE Sbjct: 975 IAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQ 1034 Query: 304 ----RLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQ 339 L KDRL ++ + LQ EK+ L+ + +L Q Sbjct: 1035 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQ 1074 Score = 36.6 bits (83), Expect = 0.034 Identities = 50/202 (24%), Positives = 91/202 (45%), Gaps = 14/202 (6%) Query: 147 ERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVN 206 E + +S E E+ + + S+I D + EL E+ +L S H + Sbjct: 1135 ENENESVIKEREDLKSLYDSLIKDHEKL-ELLHERQASEYESLIS--KHGTLKSAHKNLE 1191 Query: 207 IEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRL 266 +E + LE +L + +L+ ++ L++E+E++ + HE + E ++L E ++L Sbjct: 1192 VEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNH 1251 Query: 267 QIVNSEKPSLENELGQGE----KSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322 K E E+ Q + KS+L +E +L+ E +L K++ Q L S KL Sbjct: 1252 TYSQLLK---ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKL---KEQYQQLDITSTKL 1305 Query: 323 QIEKERLQVEKDRLRIQKEGHL 344 + E L K L ++ HL Sbjct: 1306 NNQCELLSQLKGNLE-EENRHL 1326 >gi|62244004 modulator of estrogen induced transcription isoform b [Homo sapiens] Length = 1016 Score = 63.5 bits (153), Expect = 3e-10 Identities = 47/138 (34%), Positives = 77/138 (55%), Gaps = 35/138 (25%) Query: 204 LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREK 263 LV E+ + +E RR AER + E+ER++I +ER E ERLQ E+ERL+IER+K Sbjct: 601 LVRFERLRRAMELRRRREIAERERRERERIRIIRER-----EERERLQRERERLEIERQK 655 Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQ 323 L E+ +E E +LERER+++E++R + E+E++ Sbjct: 656 L-------ERERMERE-------------------RLERERIRIEQER----RKEAERIA 685 Query: 324 IEKERLQVEKDRLRIQKE 341 E+E L+ ++ +LR ++E Sbjct: 686 REREELRRQQQQLRYEQE 703 Score = 53.1 bits (126), Expect = 3e-07 Identities = 62/242 (25%), Positives = 115/242 (47%), Gaps = 28/242 (11%) Query: 107 LTEEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSS 166 + +E DEK R+ D +N +D S T+ V++EE+ +S E + E++E + Sbjct: 451 MKKENDEKSSSRSSG--DKKNTSD----RSSKTQASVKKEEK--RSSE-KSEKKESKDTK 501 Query: 167 VIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERL 226 I +N+ E + R + P +V +++ K + + E++ Sbjct: 502 KIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKI 561 Query: 227 Q---VEKERLQIEKERLRHLDMEHER---LQLEKERLQIEREKL-------RLQIVNSEK 273 EKER ++K+R D ++ R L EK + Q RE L R + + Sbjct: 562 HGRSKEKERASLDKKR----DKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRR 617 Query: 274 PSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEK 333 E E + E+ + + E E+L+ ERERL++E+ +L+ + E E+L E+ER+++E+ Sbjct: 618 EIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERL--ERERIRIEQ 675 Query: 334 DR 335 +R Sbjct: 676 ER 677 Score = 29.6 bits (65), Expect = 4.1 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 17/96 (17%) Query: 205 VNIEKQKLE--------LEKRRLDIE------AERLQVEKERLQIEKERLRHLDMEHERL 250 + IE+QKLE LE+ R+ IE AER+ E+E L+ ++++LR+ E E+ Sbjct: 649 LEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRY---EQEKR 705 Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKS 286 K ++ + ++K SL+ + G S Sbjct: 706 NSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGS 741 >gi|63176611 modulator of estrogen induced transcription isoform a [Homo sapiens] Length = 1034 Score = 63.5 bits (153), Expect = 3e-10 Identities = 47/138 (34%), Positives = 77/138 (55%), Gaps = 35/138 (25%) Query: 204 LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREK 263 LV E+ + +E RR AER + E+ER++I +ER E ERLQ E+ERL+IER+K Sbjct: 619 LVRFERLRRAMELRRRREIAERERRERERIRIIRER-----EERERLQRERERLEIERQK 673 Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQ 323 L E+ +E E +LERER+++E++R + E+E++ Sbjct: 674 L-------ERERMERE-------------------RLERERIRIEQER----RKEAERIA 703 Query: 324 IEKERLQVEKDRLRIQKE 341 E+E L+ ++ +LR ++E Sbjct: 704 REREELRRQQQQLRYEQE 721 Score = 53.1 bits (126), Expect = 3e-07 Identities = 62/242 (25%), Positives = 115/242 (47%), Gaps = 28/242 (11%) Query: 107 LTEEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSS 166 + +E DEK R+ D +N +D S T+ V++EE+ +S E + E++E + Sbjct: 469 MKKENDEKSSSRSSG--DKKNTSD----RSSKTQASVKKEEK--RSSE-KSEKKESKDTK 519 Query: 167 VIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERL 226 I +N+ E + R + P +V +++ K + + E++ Sbjct: 520 KIEGKDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYEKI 579 Query: 227 Q---VEKERLQIEKERLRHLDMEHER---LQLEKERLQIEREKL-------RLQIVNSEK 273 EKER ++K+R D ++ R L EK + Q RE L R + + Sbjct: 580 HGRSKEKERASLDKKR----DKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRR 635 Query: 274 PSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEK 333 E E + E+ + + E E+L+ ERERL++E+ +L+ + E E+L E+ER+++E+ Sbjct: 636 EIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERERL--ERERIRIEQ 693 Query: 334 DR 335 +R Sbjct: 694 ER 695 Score = 29.6 bits (65), Expect = 4.1 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 17/96 (17%) Query: 205 VNIEKQKLE--------LEKRRLDIE------AERLQVEKERLQIEKERLRHLDMEHERL 250 + IE+QKLE LE+ R+ IE AER+ E+E L+ ++++LR+ E E+ Sbjct: 667 LEIERQKLERERMERERLERERIRIEQERRKEAERIAREREELRRQQQQLRY---EQEKR 723 Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKS 286 K ++ + ++K SL+ + G S Sbjct: 724 NSLKRPRDVDHRRDDPYWSENKKLSLDTDARFGHGS 759 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 62.0 bits (149), Expect = 8e-10 Identities = 65/325 (20%), Positives = 145/325 (44%), Gaps = 27/325 (8%) Query: 21 LKEITKRKEVIFSKQLNTTIN----VMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDW 76 ++E+TK ++ + + TI K +E Q V + Q E+KR+ Sbjct: 256 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 315 Query: 77 RALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGG 136 + L+ +++++A +G S+ L + E N W + ++ Sbjct: 316 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE------------NELWNRLNQQQEEKM 363 Query: 137 SLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRS 196 E K++E E Q E +I E+EE + RR+ E+ + E Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM-----MWEKEEKMRRQEEM 418 Query: 197 AYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKER 256 +++ + E+ E E++ ++E + + EK R Q EK + E E+ Q ++ + Sbjct: 419 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478 Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316 + + EK+R Q + E ++ + E+ + + + I E+ + E+E + ++++++ Sbjct: 479 MWRQEEKIREQ--EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR--- 533 Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341 E E++ +KE++ +++++R Q+E Sbjct: 534 -EQEEIWRQKEKIHEQEEKIRKQEE 557 Score = 49.3 bits (116), Expect = 5e-06 Identities = 25/142 (17%), Positives = 90/142 (63%), Gaps = 14/142 (9%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD----MEHERLQLEKERLQIEREK 263 +K+K+ ++ ++ + E++ ++E++ ++E++R + + E+++ ++E+++ + EK Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600 Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRL----QFLKFES 319 +R Q +++ E ++G+ E+ M + + EK++ + E+++ +++++ + ++ + Sbjct: 601 IREQEEMTQEQ--EEKMGEQEEKMCE----QEEKMQEQEEKMRRQEEKIREQEKKIREQE 654 Query: 320 EKLQIEKERLQVEKDRLRIQKE 341 EK++ ++E +Q +++++ Q+E Sbjct: 655 EKIREQEEMMQEQEEKMWEQEE 676 Score = 46.6 bits (109), Expect = 3e-05 Identities = 42/206 (20%), Positives = 106/206 (51%), Gaps = 27/206 (13%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K+ E+E + E E+EE++ R+E ++ D Sbjct: 529 EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD--------------QEEKIR 574 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDM----EHERLQLEKE 255 E V +++K+ ++ ++ + E+++ ++E Q ++E++ + + E++Q ++E Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634 Query: 256 RLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFL 315 +++ + EK+R Q +K + E + ++ M+Q Q+ EK+ + E++ +++++Q Sbjct: 635 KMRRQEEKIREQ---EKKIREQEEKIREQEEMMQEQE---EKMWEQEEKMCEQEEKMQE- 687 Query: 316 KFESEKLQIEKERLQVEKDRLRIQKE 341 + EK++ ++E++ ++ RLR Q+E Sbjct: 688 --QEEKMRRQEEKMWEQEVRLRQQEE 711 Score = 43.9 bits (102), Expect = 2e-04 Identities = 52/245 (21%), Positives = 113/245 (46%), Gaps = 37/245 (15%) Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169 E +EK+ R W+ R+ + E + E+ + + E +I E+E+ Sbjct: 421 EKEEKM--RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478 Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229 R+E ++ + ++ + E++ E EK R E E+ Q E Sbjct: 479 MWRQEEKIRE-------------QEEKIREQEEKMWRQEEKIHEQEKIR---EEEKRQ-E 521 Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ----------IVNSEKPSLENE 279 +E + ++E++R E E + +KE++ + EK+R Q + + E+ E E Sbjct: 522 QEEMWRQEEKIR----EQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577 Query: 280 ---LGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336 Q EK Q + I ++ K+ RE+ ++ +++ + + + EK+ ++E++Q +++++ Sbjct: 578 EKVWRQEEKIREQEEKIREQEEKI-REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636 Query: 337 RIQKE 341 R Q+E Sbjct: 637 RRQEE 641 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 61.6 bits (148), Expect = 1e-09 Identities = 39/126 (30%), Positives = 77/126 (61%), Gaps = 6/126 (4%) Query: 216 KRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEK-ERLQIEREKLRLQIVNSEKP 274 + L+I+ +LQ ++ + ++E+ERL ME ERL+ E+ ER ++ERE+L + + E+ Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQ 196 Query: 275 SLENELGQGEKSMLQPQDIETEKLKLERERLQ-LEKDRLQFLKFESEKL----QIEKERL 329 E + + L+ Q+ + +L+RER + E++RL+ L+ E ++ Q+E+E+L Sbjct: 197 ERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQL 256 Query: 330 QVEKDR 335 + E++R Sbjct: 257 EWERER 262 Score = 45.8 bits (107), Expect = 6e-05 Identities = 38/126 (30%), Positives = 75/126 (59%), Gaps = 15/126 (11%) Query: 224 ERLQVEKERLQIEKERLRHLDMEHERLQLEK-ERLQIEREKLRLQIVNSEKPSLENELGQ 282 E L++++ +LQ E+ R ++E ERL+ E+ ER ++ERE+L E+ LE E + Sbjct: 138 EELEIQRRQLQ---EQQRQKELERERLERERMERERLERERL-------ERERLERERLE 187 Query: 283 GEKSMLQPQDIETEKLKLERERLQLEK--DRLQFLKFESEKLQIEKERLQ-VEKDRLRIQ 339 E+ + Q+ E ++ +ERL+ ++ +R + L E ++ Q E+ERL+ +E++R + Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQERLDRERQERQ-ERERLERLERERQERE 246 Query: 340 KEGHLQ 345 ++ L+ Sbjct: 247 RQEQLE 252 Score = 37.7 bits (86), Expect = 0.015 Identities = 29/92 (31%), Positives = 52/92 (56%), Gaps = 9/92 (9%) Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQ---LEKDRLQFLK 316 + +L Q+ N PS E Q + Q + E E+ +LERER++ LE++RL+ + Sbjct: 123 QNSQLPAQVQNG--PSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERER 180 Query: 317 FESEKL---QIEKERLQVEKDRLRIQKEGHLQ 345 E E+L Q+E+ER + E+ R++++ L+ Sbjct: 181 LERERLEQEQLERERQERERQE-RLERQERLE 211 Score = 37.4 bits (85), Expect = 0.020 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 12/162 (7%) Query: 135 GGSLTEVKVEEEERDPQSPEFEIEEE----EEMLSSVIPDSRRENELPDFPHIDEFFTLN 190 G S E++++ + Q + E+E E E M + R E E + +++ Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLER 193 Query: 191 STPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERL 250 R + +E+Q+ + RLD E + Q E+ERL ERL E ER Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQERQ-ERERL----ERLERERQERER- 247 Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQ--GEKSMLQP 290 Q + ER Q+E E+ R + S+E L G+ S +P Sbjct: 248 QEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEP 289 Score = 33.1 bits (74), Expect = 0.37 Identities = 23/84 (27%), Positives = 53/84 (63%), Gaps = 10/84 (11%) Query: 266 LQIVNSEK-----PSLENELGQGEKSMLQPQDIETEKLKLERERLQ--LEKDRLQFLKFE 318 L+++NS++ P ++L ++ +++E ++ +L+ ++ Q LE++RL+ + E Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERME 167 Query: 319 SEKLQIEKERLQVEK-DRLRIQKE 341 E+L E+ERL+ E+ +R R+++E Sbjct: 168 RERL--ERERLERERLERERLEQE 189 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 61.6 bits (148), Expect = 1e-09 Identities = 39/126 (30%), Positives = 77/126 (61%), Gaps = 6/126 (4%) Query: 216 KRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEK-ERLQIEREKLRLQIVNSEKP 274 + L+I+ +LQ ++ + ++E+ERL ME ERL+ E+ ER ++ERE+L + + E+ Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQ 196 Query: 275 SLENELGQGEKSMLQPQDIETEKLKLERERLQ-LEKDRLQFLKFESEKL----QIEKERL 329 E + + L+ Q+ + +L+RER + E++RL+ L+ E ++ Q+E+E+L Sbjct: 197 ERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQL 256 Query: 330 QVEKDR 335 + E++R Sbjct: 257 EWERER 262 Score = 45.8 bits (107), Expect = 6e-05 Identities = 38/126 (30%), Positives = 75/126 (59%), Gaps = 15/126 (11%) Query: 224 ERLQVEKERLQIEKERLRHLDMEHERLQLEK-ERLQIEREKLRLQIVNSEKPSLENELGQ 282 E L++++ +LQ E+ R ++E ERL+ E+ ER ++ERE+L E+ LE E + Sbjct: 138 EELEIQRRQLQ---EQQRQKELERERLERERMERERLERERL-------ERERLERERLE 187 Query: 283 GEKSMLQPQDIETEKLKLERERLQLEK--DRLQFLKFESEKLQIEKERLQ-VEKDRLRIQ 339 E+ + Q+ E ++ +ERL+ ++ +R + L E ++ Q E+ERL+ +E++R + Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQERLDRERQERQ-ERERLERLERERQERE 246 Query: 340 KEGHLQ 345 ++ L+ Sbjct: 247 RQEQLE 252 Score = 37.7 bits (86), Expect = 0.015 Identities = 29/92 (31%), Positives = 52/92 (56%), Gaps = 9/92 (9%) Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQ---LEKDRLQFLK 316 + +L Q+ N PS E Q + Q + E E+ +LERER++ LE++RL+ + Sbjct: 123 QNSQLPAQVQNG--PSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERER 180 Query: 317 FESEKL---QIEKERLQVEKDRLRIQKEGHLQ 345 E E+L Q+E+ER + E+ R++++ L+ Sbjct: 181 LERERLEQEQLERERQERERQE-RLERQERLE 211 Score = 37.4 bits (85), Expect = 0.020 Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 12/162 (7%) Query: 135 GGSLTEVKVEEEERDPQSPEFEIEEE----EEMLSSVIPDSRRENELPDFPHIDEFFTLN 190 G S E++++ + Q + E+E E E M + R E E + +++ Sbjct: 134 GPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLER 193 Query: 191 STPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERL 250 R + +E+Q+ + RLD E + Q E+ERL ERL E ER Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQERQ-ERERL----ERLERERQERER- 247 Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQ--GEKSMLQP 290 Q + ER Q+E E+ R + S+E L G+ S +P Sbjct: 248 QEQLEREQLEWERERRISSAAAPASVETPLNSVLGDSSASEP 289 Score = 33.1 bits (74), Expect = 0.37 Identities = 23/84 (27%), Positives = 53/84 (63%), Gaps = 10/84 (11%) Query: 266 LQIVNSEK-----PSLENELGQGEKSMLQPQDIETEKLKLERERLQ--LEKDRLQFLKFE 318 L+++NS++ P ++L ++ +++E ++ +L+ ++ Q LE++RL+ + E Sbjct: 108 LEVLNSQETGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERME 167 Query: 319 SEKLQIEKERLQVEK-DRLRIQKE 341 E+L E+ERL+ E+ +R R+++E Sbjct: 168 RERL--ERERLERERLERERLEQE 189 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 61.2 bits (147), Expect = 1e-09 Identities = 66/325 (20%), Positives = 146/325 (44%), Gaps = 28/325 (8%) Query: 21 LKEITKRKEVIFSKQLNTTIN----VMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDW 76 ++E+TK ++ + + TI K +E Q V + Q E+KR+ Sbjct: 195 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 254 Query: 77 RALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGG 136 + L+ +++++A +G S+ L + E N W + ++ Sbjct: 255 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE------------NELWNRLNQQQEEKM 302 Query: 137 SLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRS 196 E K++E E Q E +I E+EE + RR+ E+ + E Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM-----MWEKEEKMRRQEEM 357 Query: 197 AYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKER 256 +++ + +E+ E E++ ++E + + EK R Q EK + E E+ Q ++ + Sbjct: 358 MWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417 Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316 + + EK+R Q + E ++ + E+ + + + I E+ + E+E + ++++++ Sbjct: 418 MWRQEEKIREQ--EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR--- 472 Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341 E E++ +KE++ E++++R Q+E Sbjct: 473 -EQEEIWRQKEKMH-EQEKIRKQEE 495 Score = 48.1 bits (113), Expect = 1e-05 Identities = 38/208 (18%), Positives = 114/208 (54%), Gaps = 22/208 (10%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K+ E+E+ E +I E+E+ I + + E + +E R + Sbjct: 429 EEKIREQEKKMWRQEEKIHEQEK-----IREEEKRQEQEEMWRQEEKIREQEEIWRQK-E 482 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259 + H E++K+ ++ ++ + E++ ++E+++ ++E++ + E+++ ++E+++ Sbjct: 483 KMH-----EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR---QEEKIREQEEKIRE 534 Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI--ETEKLKLERERLQLEKDRL----Q 313 + EK+R Q ++ E ++G+ E+ M + + + + EK++ + E+++ +K+++ + Sbjct: 535 QEEKIREQEEMMQEQ--EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592 Query: 314 FLKFESEKLQIEKERLQVEKDRLRIQKE 341 + + EK++ ++E +Q +++++ Q+E Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEE 620 Score = 48.1 bits (113), Expect = 1e-05 Identities = 31/134 (23%), Positives = 85/134 (63%), Gaps = 13/134 (9%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267 +++K+ ++ + + E++ ++E++Q E+E++R + E+++ ++E+++ ++EK+R Q Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQEEKMQ-EQEKMRR---QEEKIREQEEKIREQKEKIREQ 590 Query: 268 IVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKE 327 EK + E + ++ M+Q Q+ EK+ + E++ +++++Q + EK++ ++E Sbjct: 591 ---EEKIWEQEEKIREQEEMMQEQE---EKMWEQEEKMCEQEEKMQE---QEEKMRRQEE 641 Query: 328 RLQVEKDRLRIQKE 341 ++ ++ RLR Q+E Sbjct: 642 KMWEQEVRLRQQEE 655 Score = 47.8 bits (112), Expect = 1e-05 Identities = 39/223 (17%), Positives = 112/223 (50%), Gaps = 16/223 (7%) Query: 125 WQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHID 184 W+ R+ + E + E+ + + E +I E+E+ R+E ++ + + Sbjct: 373 WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ---E 429 Query: 185 EFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD 244 E ++ H E++K+ E++R E E + ++E+++ ++E R + Sbjct: 430 EKIREQEKKMWRQEEKIH-----EQEKIREEEKRQ--EQEEMWRQEEKIREQEEIWRQKE 482 Query: 245 MEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQD---IETEKLKLE 301 HE+ ++ K+ ++ R++ ++ + E ++ + E+ + + ++ + EK++ + Sbjct: 483 KMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542 Query: 302 RERLQLEKDRL---QFLKFESEKLQIEKERLQVEKDRLRIQKE 341 E +Q +++++ + E EK++ ++E+++ +++++R QKE Sbjct: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKE 585 Score = 47.0 bits (110), Expect = 3e-05 Identities = 30/141 (21%), Positives = 83/141 (58%), Gaps = 13/141 (9%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERLQLEKERLQIEREKL 264 +++K+ ++ ++ + E+++ ++E+++ ++E++R + E E E+E E+EK+ Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566 Query: 265 RLQIVNSEKPSLENELGQGEKSMLQPQDI----ETEKLKLERERLQLEKDRLQFLKFESE 320 R Q EK + E + +K ++ Q+ + EK++ + E +Q +++++ + E Sbjct: 567 RRQ---EEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWE---QEE 620 Query: 321 KLQIEKERLQVEKDRLRIQKE 341 K+ ++E++Q +++++R Q+E Sbjct: 621 KMCEQEEKMQEQEEKMRRQEE 641 >gi|148762940 DVL-binding protein DAPLE [Homo sapiens] Length = 2028 Score = 60.8 bits (146), Expect = 2e-09 Identities = 84/363 (23%), Positives = 160/363 (44%), Gaps = 62/363 (17%) Query: 3 QLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGE 62 QL+R+++SN Q+ +TL +E+ + KE QL + + +K + Sbjct: 516 QLEREKQSN---QDLETLSEELIREKE-----QLQSDMETLK-------------ADKAR 554 Query: 63 QRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDD-SLTEEIDEKIGFRNDA 121 Q E ++ +L+ R+R + V S + + ++ +L + + E G + Sbjct: 555 QIKDLEQEKDHLNRAMWSLRERSQ-----VSSEARMKDVEKENKALHQTVTEANGKLSQL 609 Query: 122 NFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFE-IEEEEEMLSSVIPDSRRENELPD- 179 F+ + + RD L + K + E + E + ++EE L+ + E + Sbjct: 610 EFEKRQL--HRD----LEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEA 663 Query: 180 FPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEK--ERLQIEK 237 H + L + R + D L N+ Q LE+ ++AE L++ + E ++ Sbjct: 664 LEHESQGLQLENRTLRKSLDT---LQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTS 720 Query: 238 ERLRHLDMEHERLQLEKERL------------QIEREKLRLQIVNSEKPSLENELGQGEK 285 +L ++ E+++L+ EKE L + ER +L Q V++E L+ L E Sbjct: 721 TKLAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSL---ES 777 Query: 286 SMLQPQDIETEKLKLERERLQLEKD-------RLQFLKFESEKLQIEKERLQVEKDRLRI 338 S + Q +E+E +LE ER L +D Q E ++ +E+E Q+EKD+ + Sbjct: 778 SSHKTQTLESELGELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLL 837 Query: 339 QKE 341 +KE Sbjct: 838 EKE 840 Score = 43.9 bits (102), Expect = 2e-04 Identities = 64/263 (24%), Positives = 108/263 (41%), Gaps = 56/263 (21%) Query: 103 LDDSLTEEIDEKIGFRNDANFDWQ--NVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEE 160 L++++ EI +K A+ W+ ++ D + + V E S ++E+E Sbjct: 412 LEENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKE 471 Query: 161 EEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLD 220 + L S I R D L + ++ +LE E +L Sbjct: 472 NQSLQSTIQGLR-----------DASLVLEES-------------GLKCGELEKENHQLS 507 Query: 221 IEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLR------LQIVNSEKP 274 + E+LQ + ER EK+ + L+ E L EKE+LQ + E L+ ++ + EK Sbjct: 508 KKIEKLQTQLER---EKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKD 564 Query: 275 SLENEL-GQGEKSMLQPQ----DIETEK--------------LKLERERLQLEKDRLQFL 315 L + E+S + + D+E E +LE E+ QL +D Q Sbjct: 565 HLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAK 624 Query: 316 K--FESEKLQIEKERLQVEKDRL 336 + +EKL+ E +RLQ E RL Sbjct: 625 EKGERAEKLERELQRLQEENGRL 647 Score = 42.0 bits (97), Expect = 8e-04 Identities = 55/234 (23%), Positives = 100/234 (42%), Gaps = 32/234 (13%) Query: 139 TEVKVEEEERDPQSPEFEIEE---EEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSR 195 T K+ + ER+ Q E E EE ++L ++ S R EL E L + Sbjct: 719 TSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERL-ELSYQSVSAENLRLQQSLES 777 Query: 196 SAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKE 255 S++ L + + + E + R D+EA RL Q+E +E E QLEK+ Sbjct: 778 SSHKTQTLESELGELEAERQALRRDLEALRLA----NAQLEGAEKDRKALEQEVAQLEKD 833 Query: 256 RLQIEREKLR------------------LQIVNSEKPSLENELGQGEKSMLQPQDIE--- 294 + +E+E R L V E +L+ EL + + + +++E Sbjct: 834 KKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDN 893 Query: 295 ---TEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345 T+++ + L ++ L K +S++L E ++L E +++ + +E LQ Sbjct: 894 RDLTKQVTVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLNRELLLQ 947 Score = 39.3 bits (90), Expect = 0.005 Identities = 39/153 (25%), Positives = 74/153 (48%), Gaps = 13/153 (8%) Query: 192 TPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ 251 T +R+ D+ H +EK+ L+L+ + D+E +R +K+R++ E L++ ++ Sbjct: 371 TAARARGDKVH---ELEKENLQLKSKLHDLELDR-DTDKKRIEELLEENMVLEIAQKQSM 426 Query: 252 LEKERLQIEREKL--RLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLK-----LERER 304 E L E E+L + ++ + S EL + S + + E + L+ L Sbjct: 427 NESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDAS 486 Query: 305 LQLEKDRLQFLKFESEKLQIEK--ERLQVEKDR 335 L LE+ L+ + E E Q+ K E+LQ + +R Sbjct: 487 LVLEESGLKCGELEKENHQLSKKIEKLQTQLER 519 Score = 37.4 bits (85), Expect = 0.020 Identities = 64/271 (23%), Positives = 125/271 (46%), Gaps = 41/271 (15%) Query: 100 SSDLDDSLTEEIDEKIGFR-------NDANFDWQ-NVADFRDAGGSLTEVKVEEEE---- 147 SS+LD L++E+ EK+G +D+ D + + + R+ T + ++EE+ Sbjct: 925 SSELD-KLSQEL-EKVGLNRELLLQEDDSGSDTKYKILEGRNESALKTTLAMKEEKIVLL 982 Query: 148 ----RDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFF------TLNSTPSRSA 197 + S ++E E +ML ++ R+N+ + H+ F T S + A Sbjct: 983 EAQMEEKASLNRQLESELQMLKKEC-ETLRQNQ-GEGQHLQNSFKHPAGKTAASHQGKEA 1040 Query: 198 YDEPHL-----LVNIEKQKLELEKRRLDIEAERLQVEKERLQ-IEKERL----RHLDMEH 247 + H L+ ++ + +ELE+ ++AE+ Q+ KE+LQ +E + + + L ++ Sbjct: 1041 WGPGHKEATMELLRVKDRAIELERNNAALQAEK-QLLKEQLQHLETQNVTFSSQILTLQK 1099 Query: 248 ERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI--ETEKLKLERERL 305 + L++ ++ + +LQ+ NS S L + ++LQ ETE L+R++ Sbjct: 1100 QSAFLQEHNTTLQTQTAKLQVENSTLSSQSAAL-TAQYTLLQNHHTAKETENESLQRQQE 1158 Query: 306 QLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336 QL + L + E L ER E + L Sbjct: 1159 QLTA-AYEALLQDHEHLGTLHERQSAEYEAL 1188 Score = 28.5 bits (62), Expect = 9.2 Identities = 46/195 (23%), Positives = 77/195 (39%), Gaps = 22/195 (11%) Query: 138 LTEVKVEEEERDPQSPEFEIEEEEEMLSS---VIPDSRRENELPDFPH------IDEFFT 188 L ++ E D + E+EE E++L++ + +R N L + +D Sbjct: 1204 LEHKELGERHGDMLKRKAELEEREKVLTTEREALQQEQRTNALAMGENQRLRGELDRVNF 1263 Query: 189 LNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHE 248 L+ + Y+E H K L + L+ R KE+ Q L LD E Sbjct: 1264 LHHQ-LKGEYEELHAHTKELKTSLNNAQLELNRWQARFDELKEQHQTMDISLTKLDNHCE 1322 Query: 249 RLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLE 308 L K L+ E L QI +L + ML Q++E ++ E ++ + Sbjct: 1323 LLSRLKGNLEEENHHLLSQI----------QLLSQQNQMLLEQNMENKEQYHEEQKQYI- 1371 Query: 309 KDRLQFLKFESEKLQ 323 D+L L+ EKL+ Sbjct: 1372 -DKLNALRRHKEKLE 1385 >gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] Length = 523 Score = 60.1 bits (144), Expect = 3e-09 Identities = 63/219 (28%), Positives = 103/219 (47%), Gaps = 28/219 (12%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E ++ E+E + E + E+EE L R + E L R Sbjct: 198 EERLREQEERLREQEERLREQEERLCEQEERLREQEE-----------RLREQEERLCEQ 246 Query: 200 EPHLLVNIEK-----QKLELEKRRLDIEAERLQVEKERLQIEKERLRH----LDMEHERL 250 E L + E+ ++L ++ RL + ERL ++ERL ++ERLR L + ERL Sbjct: 247 EERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERL 306 Query: 251 QLEKERLQIEREKLRLQ---IVNSEK-PSLENELGQGEKSMLQPQDIETEKLKLERERLQ 306 + ++ERL + E+LR Q + EK P E L + EK + Q + E ++ LERERL Sbjct: 307 REQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLL 366 Query: 307 LEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345 E + L E E+L+ + ERL ++ +++ L+ Sbjct: 367 EEVEEL----LEQERLRQQDERLWQQETLQELERLRELE 401 Score = 57.4 bits (137), Expect = 2e-08 Identities = 44/139 (31%), Positives = 82/139 (58%), Gaps = 19/139 (13%) Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIERE 262 LL ++++L ++ RL + ERL+ ++ERL ++ERLR + ERL+ ++ERL + E Sbjct: 192 LLNRRQEERLREQEERLREQEERLREQEERLCEQEERLRE---QEERLREQEERLCEQEE 248 Query: 263 KLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322 +LR E L + E+ + + + E+L+ + ERL +++RL + E+L Sbjct: 249 RLREH---------EERLCEQEERLCEQE----ERLREQEERLHEQEERLCE---QEERL 292 Query: 323 QIEKERLQVEKDRLRIQKE 341 + ++ERL +++RLR Q+E Sbjct: 293 REQEERLCEQEERLREQEE 311 Score = 53.1 bits (126), Expect = 3e-07 Identities = 44/132 (33%), Positives = 77/132 (58%), Gaps = 15/132 (11%) Query: 210 QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIV 269 Q L L RR + ERL+ ++ERL+ ++ERLR + ERL ++ERL+ + E+LR Q Sbjct: 188 QMLSLLNRR---QEERLREQEERLREQEERLRE---QEERLCEQEERLREQEERLREQ-- 239 Query: 270 NSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERL 329 E L + E+ + + + E+L + ERL+ +++RL + E+L ++ERL Sbjct: 240 EERLCEQEERLREHEERLCEQE----ERLCEQEERLREQEERLHE---QEERLCEQEERL 292 Query: 330 QVEKDRLRIQKE 341 + +++RL Q+E Sbjct: 293 REQEERLCEQEE 304 Score = 49.7 bits (117), Expect = 4e-06 Identities = 43/140 (30%), Positives = 78/140 (55%), Gaps = 26/140 (18%) Query: 209 KQKLELEKRRLDIEAERLQV-------EKERLQIEKERLRHLDMEHERLQLEKERLQIER 261 +++LE R+L E E Q+ ++ERL+ ++ERLR + ERL+ ++ERL + Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLRE---QEERLREQEERLCEQE 226 Query: 262 EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321 E+LR Q E L + E+ + + + E+L+ ERL +++RL + E+ Sbjct: 227 ERLREQ---------EERLREQEERLCEQE----ERLREHEERLCEQEERLCE---QEER 270 Query: 322 LQIEKERLQVEKDRLRIQKE 341 L+ ++ERL +++RL Q+E Sbjct: 271 LREQEERLHEQEERLCEQEE 290 Score = 37.0 bits (84), Expect = 0.026 Identities = 40/157 (25%), Positives = 79/157 (50%), Gaps = 10/157 (6%) Query: 189 LNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHE 248 +NS S ++ H + ++K L K + + AE L E + E+L+ + H Sbjct: 112 INSLVRTSKEEKKHEIHLVQKLGRSLFKLK-NQTAEPLAPEPPAGPSKVEQLQD-ETNHL 169 Query: 249 RLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLE 308 R +LE Q++ E Q+++ E L + E+ + + + E+L+ + ERL + Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQE----ERLREQEERLCEQ 225 Query: 309 KDRL----QFLKFESEKLQIEKERLQVEKDRLRIQKE 341 ++RL + L+ + E+L ++ERL+ ++RL Q+E Sbjct: 226 EERLREQEERLREQEERLCEQEERLREHEERLCEQEE 262 Score = 32.7 bits (73), Expect = 0.49 Identities = 32/84 (38%), Positives = 45/84 (53%), Gaps = 5/84 (5%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD--MEHERLQLEKERLQIEREKLR 265 E+Q+ LE+ RL E E L +E+ERL+ + ERL + E ERL+ + L++ E L Sbjct: 354 EEQERLLERERLLEEVEEL-LEQERLRQQDERLWQQETLQELERLRELERMLELGWEALY 412 Query: 266 LQIVNSEKPSLENELGQGEKSMLQ 289 Q +E S EL KS LQ Sbjct: 413 EQ--RAEPRSGFEELNNENKSTLQ 434 >gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 479 Score = 60.1 bits (144), Expect = 3e-09 Identities = 53/146 (36%), Positives = 83/146 (56%), Gaps = 17/146 (11%) Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL----RHLDMEHERLQLEKERLQ 258 LL ++++L ++ RL + ERL ++ERL ++ERL L + ERL+ ++ERL Sbjct: 192 LLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLH 251 Query: 259 IEREKLRLQ---IVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFL 315 + E+L Q + E+ E E G++ +L+ E EKL LE+ER Q E++RL Sbjct: 252 EQEERLCEQEERLCEQEERLCEQEKLPGQERLLE----EVEKL-LEQERRQEEQERL--- 303 Query: 316 KFESEKLQIEKERLQVEKDRLRIQKE 341 E E+L E E L +E++RLR Q E Sbjct: 304 -LERERLLDEVEEL-LEQERLRQQDE 327 Score = 36.2 bits (82), Expect = 0.044 Identities = 64/210 (30%), Positives = 94/210 (44%), Gaps = 35/210 (16%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203 E+EER + E E+EE + R E + H E L R E L Sbjct: 217 EQEERLCEQEERLCEQEERLREQ----EERLREQEERLHEQEE-RLCEQEERLCEQEERL 271 Query: 204 LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ------LEKERL 257 E++KL ++R L+ E E+L +E+ER Q E+ERL +E ERL LE+ERL Sbjct: 272 C---EQEKLPGQERLLE-EVEKL-LEQERRQEEQERL----LERERLLDEVEELLEQERL 322 Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317 + + E+L Q E L E L+ E E+L+ L+L + L + Sbjct: 323 RQQDERLWQQETLRELERLR------ELERLR----ELERLRELERMLELGWEALYEQRA 372 Query: 318 ES----EKLQIE-KERLQVEKDRLRIQKEG 342 E E+L E K LQ+E+ ++K G Sbjct: 373 EPRSGFEELNNENKSTLQLEQQVKELEKSG 402 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 59.3 bits (142), Expect = 5e-09 Identities = 66/334 (19%), Positives = 145/334 (43%), Gaps = 31/334 (9%) Query: 21 LKEITKRKEVIFSKQLNTTIN----VMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDW 76 ++E+TK ++ + + TI K +E Q V + Q E+KR+ Sbjct: 195 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 254 Query: 77 RALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGG 136 + L+ +++++A +G S+ L + E N W + ++ Sbjct: 255 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE------------NELWNRLNQQQEEKM 302 Query: 137 SLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENEL-----PDFPHIDEFFTLNS 191 E K++E E Q E +I E+EE + RR+ E+ +E Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 362 Query: 192 TPSR----SAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEH 247 R +++ + E+ E E++ ++E + + EK R Q EK + E Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422 Query: 248 ERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQL 307 E+ Q ++ ++ + EK+R Q + E ++ + E+ + + + I E+ + E+E + Sbjct: 423 EKRQEQEAKMWRQEEKIREQ--EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480 Query: 308 EKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 +++++ E E++ +KE++ +++++R Q+E Sbjct: 481 QEEKIH----EQEEIWRQKEKMHEQEEKIRKQEE 510 Score = 49.7 bits (117), Expect = 4e-06 Identities = 50/253 (19%), Positives = 123/253 (48%), Gaps = 42/253 (16%) Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169 E +EKI R W+ R+ E K+ E+E E +I E+EEM Sbjct: 500 EQEEKI--RKQEEKVWRQEEKIREQ-----EEKIREQEEKMWRQEEKIREQEEMW----- 547 Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229 R E ++ + I E + E + +++K+ ++ ++ + E+ Q + Sbjct: 548 --REEEKMHEQEKIWEEEKRQEQEDKMWRQEEK--IREQEEKVWRQEEKIREQEEKRQEQ 603 Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQ 289 +E++ ++E++R + E++Q ++E+++ + EK+R Q +++ E ++G+ E+ M + Sbjct: 604 EEKMWKQEEKIRE---QEEKIQEQEEKIREQEEKIREQEEMTQEQ--EEKMGEQEEKMCE 658 Query: 290 PQDIETE-----------------KLKLERERLQLEKDRLQFLKF----ESEKLQIEKER 328 ++ E K++ + E+++ +++ +Q + + EK+ ++E+ Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718 Query: 329 LQVEKDRLRIQKE 341 +Q +++++R Q+E Sbjct: 719 MQEQEEKMRRQEE 731 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 58.5 bits (140), Expect = 8e-09 Identities = 87/382 (22%), Positives = 162/382 (42%), Gaps = 64/382 (16%) Query: 5 KRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGEQR 64 +++R+ F +E + + +R+ + L + +R +++ + + + E ++R Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER 862 Query: 65 TGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGF------- 117 ++ +RR WR ++ +R + L + L +E +E++ Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922 Query: 118 RNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEF----EIEEEEEMLSSVIPDSRR 173 R + ++ + L + E+ R + ++ +++++EE L P+ RR Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982 Query: 174 ENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKL--ELEKRRLDIEAERLQVEKE 231 E Y E L E+Q L E EKRR E ER +K+ Sbjct: 983 RQE-----------------REKKYREEEELQQEEEQLLREEREKRRRQ-EWERQYRKKD 1024 Query: 232 RLQIEKERLRHLDMEHERLQLEKERLQIEREKLRL---QIVNSEKPSL-----------E 277 LQ E+E+L + E RLQ E+ER E E+L+ Q++ E+ + E Sbjct: 1025 ELQQEEEQLLREEREKRRLQ-ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083 Query: 278 NELGQGEKSMLQP------------QDIETEKLKLERERL---QLEKDRLQFLKF---ES 319 EL Q E+ +L+ Q E E+L+ E E+L + EK R Q L+ E Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143 Query: 320 EKLQIEKERLQVEKDRLRIQKE 341 E++Q E+E+L E+ R ++E Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQE 1165 Score = 57.0 bits (136), Expect = 2e-08 Identities = 58/199 (29%), Positives = 92/199 (46%), Gaps = 31/199 (15%) Query: 142 KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEP 201 +++E ER + E E+++EEE L ++RR EL +E +E Sbjct: 1042 RLQERERQYREEE-ELQQEEEQLLGEERETRRRQELERQYRKEE---------ELQQEEE 1091 Query: 202 HLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIER 261 LL +++ E+ R E E LQ E+E+L + +ER + E ER E+E +Q E Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQL-LREEREKRRRQELERQYREEEEVQQEE 1150 Query: 262 EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321 E+L L E + + L+ Q E E+L+ E E Q L+ E EK Sbjct: 1151 EQL-----------LREEPEKRRRQELERQYREEEELQQEEE---------QLLREEQEK 1190 Query: 322 LQIEKERLQVEKDRLRIQK 340 + E+ER E++ L+ QK Sbjct: 1191 RRQERERQYREEEELQRQK 1209 Score = 55.5 bits (132), Expect = 7e-08 Identities = 56/229 (24%), Positives = 100/229 (43%), Gaps = 27/229 (11%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 +++ E + + + + E EE+ L D + E P + L R + Sbjct: 1612 QLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFRE 1671 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEK---------ERLQIEKERLRHLDMEHERL 250 E LL E+Q+L ++R E Q+ + E Q+ ++ L E E+L Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731 Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQL--- 307 + E E+ Q+ R++ +I+ E+ E E Q + + E E+L+ ERE QL Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791 Query: 308 EKDRL----QFLKFESEKLQI-----------EKERLQVEKDRLRIQKE 341 E DR + L+ E E+ Q+ E+E+LQ+E+ R+++E Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE 1840 Score = 54.7 bits (130), Expect = 1e-07 Identities = 43/148 (29%), Positives = 79/148 (53%), Gaps = 21/148 (14%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267 E+++L+ +R A++LQ E++ LQ ++ER R + + +K R Q+E E+ R + Sbjct: 836 EEEQLQRRER-----AQQLQEEEDGLQEDQERRRSQEQRRD----QKWRWQLEEERKRRR 886 Query: 268 IVNSEKPSLENELGQGEKSMLQPQDIETEKLKLE-----------RERLQLEKDRLQFLK 316 KP+L+ +L + E+ +LQ ++ E ++ + E RE QL+++ Q L+ Sbjct: 887 HTLYAKPALQEQLRK-EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945 Query: 317 FESEKLQIEKERLQVEKDRLRIQKEGHL 344 E EK + ++ Q KD+ QKE L Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQL 973 Score = 52.0 bits (123), Expect = 8e-07 Identities = 59/223 (26%), Positives = 105/223 (47%), Gaps = 21/223 (9%) Query: 140 EVKVEEEERDPQSPEFEIEEE--EEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSR-- 195 +++ E++ER Q + E EEE E+ L + RRE EL + + S + Sbjct: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQ 705 Query: 196 ----SAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ 251 S D V +K E ++RR + E +R + E E E+ER E E+ + Sbjct: 706 WQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRR 765 Query: 252 LEKERLQIEREKLRLQIVNSEKPSL----ENELGQGEKSMLQPQDIETEKLKLERERLQL 307 + Q E + R + S +P L E +L E+ + + + E+ K +R R + Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR 825 Query: 308 EKDR-LQFLKFE--------SEKLQIEKERLQVEKDRLRIQKE 341 E+++ LQFL+ E +++LQ E++ LQ +++R R Q++ Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868 Score = 49.7 bits (117), Expect = 4e-06 Identities = 57/211 (27%), Positives = 99/211 (46%), Gaps = 19/211 (9%) Query: 141 VKVEEEERDPQSPEFEIE---EEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSA 197 +K+EEEER Q E + E+EE + E L ++ R Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE- 547 Query: 198 YDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKER--LRHLDMEHERLQLEKE 255 LL E+++LE E+R ++ E+ + + L+ E+ER R + ERL+ + Sbjct: 548 ----QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK 603 Query: 256 RLQIER---EKLRLQIVNSEKPSLENE---LGQGEKSMLQPQDIETEKLKLERERL--QL 307 R ++ER E+ R Q + E+P E L E+ + Q + E+ + +RL + Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE 663 Query: 308 EKDRL-QFLKFESEKLQIEKERLQVEKDRLR 337 E++RL Q LK E E+ + E+E + E+++ R Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQAR 694 Score = 48.5 bits (114), Expect = 9e-06 Identities = 52/207 (25%), Positives = 99/207 (47%), Gaps = 16/207 (7%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E ++ E++ + + E+EEE RRE L E R Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR-----EQEERRDWLKREEET 464 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAER-LQVEKERLQIEKERLRHLDMEHERLQLEKERLQ 258 E H E++K +L++ + + ER L++E+E + ++ER R + E+ + ++RL+ Sbjct: 465 ERH---EQERRKQQLKRDQEEERRERWLKLEEEERREQQER-REQQLRREQEERREQRLK 520 Query: 259 IEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKD----RLQF 314 + E+ RLQ + L E + + +L+ + E ++L+ ER +L+++ R Q Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKRE--EEKRLEQERREQRLKREQEERRDQL 578 Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341 LK E E+ Q +R Q E+ R+++E Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKRE 605 Score = 47.4 bits (111), Expect = 2e-05 Identities = 55/221 (24%), Positives = 97/221 (43%), Gaps = 38/221 (17%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203 EE++ Q E + EEE++ R+E E + + R +E L Sbjct: 1712 EEQQLRRQELERKFREEEQL--------RQETEQEQLRRQERY--------RKILEEEQL 1755 Query: 204 LVNIEKQKLELEKR-RLDIEAERLQVEKERLQI----------EKERLRHLDMEHE---- 248 E+Q+L ++R R E E+L+ E+E Q+ E+E+LR E + Sbjct: 1756 RPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ 1815 Query: 249 ----RLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI---ETEKLKLE 301 + + E+E+LQ+E ++ RL+ + E + EKS + Q++ E +K + E Sbjct: 1816 QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQE 1875 Query: 302 RERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEG 342 RER E+ + K E Q+ + + Q K R+ + G Sbjct: 1876 RERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPG 1916 Score = 47.0 bits (110), Expect = 3e-05 Identities = 61/220 (27%), Positives = 93/220 (42%), Gaps = 42/220 (19%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203 +E ER + E E+++EEE L P+ RR EL Y E Sbjct: 1134 QELERQYREEE-EVQQEEEQLLREEPEKRRRQEL-----------------ERQYREEEE 1175 Query: 204 LVNIEKQKL--ELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHE---RLQLEKERLQ 258 L E+Q L E EKRR E ER E+E LQ +K + R+ D + + Q E E+ Sbjct: 1176 LQQEEEQLLREEQEKRRQ--ERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKEN 1233 Query: 259 IERE-------KLRLQIVNSEKPSLENELGQGEKSML----QPQDIETEKLKLER----- 302 R+ + Q E L + Q + L Q +D E E+ + ++ Sbjct: 1234 AVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHF 1293 Query: 303 -ERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 E QLE++ + K K Q EK+ L+ E++ R ++E Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333 Score = 47.0 bits (110), Expect = 3e-05 Identities = 55/236 (23%), Positives = 98/236 (41%), Gaps = 37/236 (15%) Query: 142 KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEP 201 K E+E Q PE + EEE+ L + E + R +E Sbjct: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561 Query: 202 HLLVNIEKQKLELEKR----RLDIEAERLQVEKERLQIEKERLR------HLDMEHERLQ 251 L E+Q+L ++R RL+ + R Q ++ + ++++LR L E +R Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621 Query: 252 LEKERLQIEREKLRLQIVNSEKPSLENE--------------------------LGQGEK 285 E E+L ERE+ +L ++ LE E L +GE+ Sbjct: 1622 REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE 1681 Query: 286 SMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 L+ Q+ K + E ++L+ ++ +FL+ E + + E ER E+++LR + E Sbjct: 1682 QQLRRQE-RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736 Score = 45.8 bits (107), Expect = 6e-05 Identities = 59/225 (26%), Positives = 100/225 (44%), Gaps = 41/225 (18%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSR---SAYDE 200 +E++R ++E E+E + + + RENE +F L + R S D Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENE--------QFRQLEDSQLRDRQSQQDL 1267 Query: 201 PHLLVNIEKQKLELEKRRLDI------EAERLQVEKER--------LQIEKERLRHLDME 246 HLL +++ E E+RR E E+L+ E+++ Q EK+ LR E Sbjct: 1268 QHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327 Query: 247 HERLQ------LEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKL 300 R Q E+E+L ERE+ L+ ++ E EL E+ K Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG---------RKFLE 1378 Query: 301 ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345 E +RL+ ++ +FLK E ++L+ ++ Q+ +DR R +E Q Sbjct: 1379 EEQRLRRQERERKFLK-EEQQLRCQEREQQLRQDRDRKFREEEQQ 1422 Score = 45.4 bits (106), Expect = 7e-05 Identities = 55/213 (25%), Positives = 108/213 (50%), Gaps = 18/213 (8%) Query: 140 EVKVEEEERDPQSPEFEIEEE--EEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSA 197 +++ E+EER Q E EEE E+ L + RRE +L + L Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR------ 391 Query: 198 YDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL 257 E L + ++ + +R + E+ +++L+ E+E RH + +HE+ + E +RL Sbjct: 392 --EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH-EQKHEQERRE-QRL 447 Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEK--LKL-ERERLQLEKDRLQF 314 + E+E+ R + E+ + +E + ++ + + Q+ E + LKL E ER + ++ R Q Sbjct: 448 KREQEE-RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506 Query: 315 LKFESEKLQIEKERLQVEKDRL--RIQKEGHLQ 345 L+ E E+ + ++ + Q E++RL R++ E L+ Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLR 539 Score = 43.5 bits (101), Expect = 3e-04 Identities = 46/207 (22%), Positives = 89/207 (42%), Gaps = 23/207 (11%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHL 203 +EE R+ Q + EE E + RRE +L E L Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQL-------------RREQEEERREQQL 364 Query: 204 LVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREK 263 E+++ E + RR Q+ +E+ +++LR QL +E+ Q+ RE+ Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ-QLRREQ 423 Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDI---------ETEKLKLERERLQLEKDRLQF 314 + E+ ++E + E+ + + Q+ ETE+ + ER + QL++D+ + Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483 Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341 + KL+ E+ R Q E+ ++++E Sbjct: 484 RRERWLKLEEEERREQQERREQQLRRE 510 Score = 42.7 bits (99), Expect = 5e-04 Identities = 50/236 (21%), Positives = 106/236 (44%), Gaps = 10/236 (4%) Query: 109 EEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVI 168 EE ++ R D F + ++R L + + + +E +PQ EEEE++ Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283 Query: 169 PDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQV 228 + RRE + + + L E E+++ + E+R E Q+ Sbjct: 284 QELRRERQEEE----QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339 Query: 229 EKERLQIEKERLRHLDMEHER---LQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEK 285 +E+ + +++LR E R L+ E+E + E++ R Q + E+ + + E+ Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399 Query: 286 SMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 + + Q + E+ +L RE+ QL +++ Q + + E+ +K + + RL+ ++E Sbjct: 400 QLRREQQLRREQ-QLRREQ-QLRREQ-QLRREQEEERHEQKHEQERREQRLKREQE 452 Score = 42.4 bits (98), Expect = 6e-04 Identities = 49/227 (21%), Positives = 96/227 (42%), Gaps = 25/227 (11%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSR-RENELP------DFPHIDEFFTLNSTPSRS 196 E E++ Q + + EEE+ LS D + RE E + ++E L R Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462 Query: 197 AYDEPHLLVNIEKQKLELEKRRLDIEAERLQV-----------------EKERLQIEKER 239 +E LL E+Q+L ++R E Q+ E ER +E+E+ Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522 Query: 240 LRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLK 299 H + E+++L+ + + + K E +L Q + + K + Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFR 1582 Query: 300 LERERLQLEKDRLQFLKFESE-KLQIEKERLQVEKDRLRIQKEGHLQ 345 LE ++++ ++ +F++ E + + Q +++L+ E+DR + E LQ Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629 Score = 42.0 bits (97), Expect = 8e-04 Identities = 52/214 (24%), Positives = 100/214 (46%), Gaps = 18/214 (8%) Query: 135 GGSLTEVKVEEEERDPQSPEFEI--------EEEEEMLSSVIPDSRRENELPDFPHIDEF 186 G +E + E+RD Q + E+ E EE S + +E +FP ++ Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210 Query: 187 FTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKER-LQIEKERLRHLDM 245 R E ++Q+ E + R E E+ ++E L+ E+E+L+ + Sbjct: 211 RRRELLELRRKGREEK-----QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265 Query: 246 EHER-LQLEKERL-QIEREKLRLQIVNSEKPS--LENELGQGEKSMLQPQDIETEKLKLE 301 + +R LQ E+E+L ++ER++LR + E+ L E K + ++ + E+ + + Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325 Query: 302 RERLQLEKDRLQFLKFESEKLQIEKERLQVEKDR 335 R Q E+ R Q L+ E E+ + ++ R + E++R Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEER 359 Score = 41.6 bits (96), Expect = 0.001 Identities = 53/225 (23%), Positives = 98/225 (43%), Gaps = 29/225 (12%) Query: 124 DWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHI 183 D Q+ D + G E E+E R Q + EEE++ +++R + Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD-------- 1311 Query: 184 DEFFTLNSTPSRSAYDEPHLL--VNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLR 241 R + +E LL EK++ + R+ E + LQ +E+ +ER R Sbjct: 1312 -----------RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360 Query: 242 HLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLE 301 E R Q + + E ++LR Q + E +L E+ QD + + + E Sbjct: 1361 KFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420 Query: 302 RERLQLEKDRLQFLKFESEKLQI---EKERLQVEKDRLRIQKEGH 343 ++ + E+DR KF E+ Q+ E+ER +E+++ ++++E H Sbjct: 1421 QQLSRQERDR----KFREEEQQVRRQERERKFLEEEQ-QLRQERH 1460 Score = 40.8 bits (94), Expect = 0.002 Identities = 31/133 (23%), Positives = 66/133 (49%), Gaps = 8/133 (6%) Query: 213 ELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSE 272 E + RR ++ R + +E+ Q +ER + E E + K + +E+ +LQ E Sbjct: 207 EEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ---EE 263 Query: 273 KPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVE 332 +P + EL + E+ + + E+ +L RER + E+ + + + + + + E+ER + + Sbjct: 264 EPQRQRELQEEEEQLRK-----LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318 Query: 333 KDRLRIQKEGHLQ 345 ++R Q+ Q Sbjct: 319 EERREQQERREQQ 331 Score = 38.9 bits (89), Expect = 0.007 Identities = 47/206 (22%), Positives = 93/206 (45%), Gaps = 10/206 (4%) Query: 145 EEERDPQSPEFEIEEEEEMLSSVIPDSRRENELP------DFPHIDEFFTLNSTPSRSAY 198 EE+R Q + + EEE++L R E + H ++ R Sbjct: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR 1385 Query: 199 DEPHLLVNIEKQKLELEKRRLDIEAERLQV--EKERLQIEKERLRHLDMEHERL-QLEKE 255 E E+Q+L ++R + +R + E+E+ +ER R E +++ + E+E Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445 Query: 256 RLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFL 315 R +E E+ Q + + E L + E+ L Q+ + + L+ E++ + E+DR +F Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR-KFR 1504 Query: 316 KFESEKLQIEKERLQVEKDRLRIQKE 341 + E + E++ L+ E+ R Q++ Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQ 1530 Score = 37.4 bits (85), Expect = 0.020 Identities = 59/235 (25%), Positives = 96/235 (40%), Gaps = 41/235 (17%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E ++++ R Q E EE E L + R E E + Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERRE----------QRLKREQEER 574 Query: 200 EPHLLVNIEKQKLELEKR----RLD-----IEAERLQVEKERLQ------IEKERLRHL- 243 LL E+++ + KR RL+ E ERL+ E+ R Q E+ER + L Sbjct: 575 RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634 Query: 244 --DMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLE 301 + + ER Q + R Q ER + RL+ E+ LE L + + + Q++ E+ + Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLK-REEEEERLEQRLKREHEEERREQELAEEEQEQA 693 Query: 302 RER-----------LQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEGHLQ 345 RER L+ E D Q + + Q E +R + E++ R ++E LQ Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQ-EGQRRRQEQEEKRRRRESELQ 747 Score = 35.4 bits (80), Expect = 0.075 Identities = 53/221 (23%), Positives = 99/221 (44%), Gaps = 24/221 (10%) Query: 133 DAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNST 192 D SL + + +EE++ P EEE +E EL + E Sbjct: 104 DGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ 163 Query: 193 PSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQI----------EKERLRH 242 R DE + +Q+ E ++R E + E+E+LQ ++E+LR Sbjct: 164 RDRQRRDE-----ELWRQRQEWQER------EERRAEEEQLQSCKGHETEEFPDEEQLRR 212 Query: 243 LDMEHERLQLEKERLQIEREKL-RLQIVNSEKPSLENE-LGQGEKSMLQPQDIETEKLKL 300 ++ R + +E+ Q RE+ R+ EK + E + + E+ LQ ++ + ++ +L Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR-EL 271 Query: 301 ERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 + E QL K Q L+ E ++ + +++RL+ E+ R Q+E Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312 Score = 33.1 bits (74), Expect = 0.37 Identities = 27/122 (22%), Positives = 64/122 (52%), Gaps = 3/122 (2%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267 E+++ +L + + + +RL+ E+E ++E+ R + E +L +E + RE+++ + Sbjct: 641 ERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR 700 Query: 268 IVNSEKPSLENEL-GQGEKSMLQPQDIETEKLKLERERLQLEKD-RLQFLKFESEKLQIE 325 I + LE+E + K +P+ E ++ + E+E + ++ LQ+ + E Q + Sbjct: 701 IPKWQW-QLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQ 759 Query: 326 KE 327 +E Sbjct: 760 EE 761 Score = 30.8 bits (68), Expect = 1.9 Identities = 37/183 (20%), Positives = 77/183 (42%), Gaps = 31/183 (16%) Query: 142 KVEEEERDPQSPEFEIEEEE---EMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAY 198 ++E+EER Q + E EEE ++L S + RR+ +L Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL--------------------- 647 Query: 199 DEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQ 258 E+Q+ ++ + + E ERL+ +R E+ R + L E + E+ + + Sbjct: 648 -------RREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR 700 Query: 259 IEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFE 318 I + + +L+ + S + ++ + Q+ E ++ + E E E++R + E Sbjct: 701 IPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE 760 Query: 319 SEK 321 E+ Sbjct: 761 EEQ 763 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 57.8 bits (138), Expect = 1e-08 Identities = 58/224 (25%), Positives = 114/224 (50%), Gaps = 21/224 (9%) Query: 125 WQNVADFRDAGGSLTEV--KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPH 182 W+ R+ G + E K+ +E+ + E E+ E+E+ L +E ++ + Sbjct: 258 WRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 317 Query: 183 -IDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLR 241 + E + + L EKQ E E++ D E ER+ + ERL+ ++ER+R Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQE-ERMWEQDERLREKEERMR 376 Query: 242 HLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENE---LGQGEKSMLQPQDI-ETEK 297 E E++ ++E++Q E E++R EK E E Q EK Q +++ E E+ Sbjct: 377 ----EQEKMWEQEEKMQ-EEERIR----EREKKMREEEETMREQEEKMQKQEENMWEQEE 427 Query: 298 LKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 + +++RL +K++L +E EK+Q ++E++ +++++R Q+E Sbjct: 428 KEWQQQRLPEQKEKL----WEQEKMQEQEEKIWEQEEKIRDQEE 467 Score = 53.1 bits (126), Expect = 3e-07 Identities = 39/224 (17%), Positives = 116/224 (51%), Gaps = 24/224 (10%) Query: 125 WQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHID 184 W+ RD E K+ ++E + + E+EE + ++E ++ + Sbjct: 489 WEQEEKMRDQ-----EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQ 543 Query: 185 EFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD 244 E + +D+ + E++++ ++++ E E ++ ++E++Q ++E++R + Sbjct: 544 E-------QEKKTWDQEEKMR--EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594 Query: 245 M----EHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI---ETEK 297 + E++Q ++E++ + EK+ Q + E + + E+ M + ++ + EK Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654 Query: 298 LKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 ++ + E+++ +++++Q + EK++ ++E++Q +++++R Q+E Sbjct: 655 MREQEEKMREQEEKMQG---QEEKMREQEEKMQGQEEKMREQEE 695 Score = 48.5 bits (114), Expect = 9e-06 Identities = 73/352 (20%), Positives = 158/352 (44%), Gaps = 44/352 (12%) Query: 1 MKQLKRK-RKSNFSVQETQT--LLKEITKRKEVIFSKQLNTTINVMKRMAW---EEIAQC 54 +K+LKRK ++ F + + QT L +E+ +++E + ++ I + W E + + Sbjct: 210 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEEL--REQEKKIRKQEEKMWRQEERLREQ 267 Query: 55 VNAVGEGEQRTGTEVKRRYLDWRALMKR-KRMKANIKLVGSGFPLPSSDL----DDSLTE 109 + E E++ + KR + L ++ K ++ KL + + + Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327 Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169 E +EK+ +R + W+ R+ E K+ ++E + + E+EE + Sbjct: 328 EQEEKM-WRQEERL-WEQEKQMREQ-----EQKMRDQEERMWEQDERLREKEERMREQEK 380 Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229 +E ++ + I E E + +++K++ ++ + E E + + Sbjct: 381 MWEQEEKMQEEERIRE--------REKKMREEEETMREQEEKMQKQEENM-WEQEEKEWQ 431 Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQ 289 ++RL +KE+L E E++Q ++E++ + EK+R Q E GQ +K Q Sbjct: 432 QQRLPEQKEKL----WEQEKMQEQEEKIWEQEEKIRDQ---------EEMWGQEKKMWRQ 478 Query: 290 PQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 + E E E+E +D+ Q + + E++ + ERL+ +++R+R QK+ Sbjct: 479 EKMREQEDQMWEQEEKM--RDQEQKMWDQEERMWEQDERLREKEERMREQKK 528 Score = 44.3 bits (103), Expect = 2e-04 Identities = 35/134 (26%), Positives = 75/134 (55%), Gaps = 16/134 (11%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267 E Q E E++ D E +++ ++ER+ + ERLR E E E++++ + EK+R Sbjct: 485 EDQMWEQEEKMRDQE-QKMWDQEERMWEQDERLR----EKEERMREQKKMWQQEEKMR-- 537 Query: 268 IVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKE 327 EK + E E +K+ Q + + E+ ERE+ E++ + ++ + EK+Q ++E Sbjct: 538 ---EEKKTQEQE----KKTWDQEEKMREEERMREREKKMREEEEM--MREQEEKMQEQEE 588 Query: 328 RLQVEKDRLRIQKE 341 +++ +++++ Q+E Sbjct: 589 KMREQEEKMWEQEE 602 Score = 44.3 bits (103), Expect = 2e-04 Identities = 49/233 (21%), Positives = 108/233 (46%), Gaps = 30/233 (12%) Query: 109 EEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVI 168 E + EK + WQ R+ E K +E+E+ E ++ EEE M Sbjct: 514 ERLREKEERMREQKKMWQQEEKMRE------EKKTQEQEKKTWDQEEKMREEERMRERE- 566 Query: 169 PDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQV 228 R E E+ ++ + + E + EK + + EK E Q Sbjct: 567 KKMREEEEMMR----EQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622 Query: 229 EKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSML 288 E++++Q ++E + + E++Q ++E++ + EK+R Q EK + E QG++ Sbjct: 623 EEDKMQEQEEMMWE---QEEKMQEQEEKMWEQEEKMREQ---EEKMREQEEKMQGQE--- 673 Query: 289 QPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 EK++ + E++Q +++++ + + EK++ ++E++ +++++ Q+E Sbjct: 674 -------EKMREQEEKMQGQEEKM---REQEEKMRGQEEKMWGQEEKMWGQEE 716 Score = 42.4 bits (98), Expect = 6e-04 Identities = 40/141 (28%), Positives = 73/141 (51%), Gaps = 17/141 (12%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQ--IEREKLR 265 E+ L LE R I E L+ + LQ E+LR + E +QL + L+ +ER K Sbjct: 167 ERDALSLELYRNTITNEELKKKNAELQ---EKLRLAESEKSEIQLNVKELKRKLERAKFL 223 Query: 266 LQIVNS-----EKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESE 320 L V + E E EL + EK + + + EK+ + ERL+ ++ + ++ + E Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRK----QEEKMWRQEERLREQEGK---MREQEE 276 Query: 321 KLQIEKERLQVEKDRLRIQKE 341 K++ +++RL+ ++ LR Q++ Sbjct: 277 KMRRQEKRLREQEKELREQEK 297 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 57.0 bits (136), Expect = 2e-08 Identities = 69/348 (19%), Positives = 160/348 (45%), Gaps = 51/348 (14%) Query: 6 RKRKSNFSVQETQ---------TLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVN 56 +KR N ++ET T ++++TK ++ + + TI EE+ + Sbjct: 168 QKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITD------EELKEKNA 221 Query: 57 AVGEGEQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIG 116 + E + +E L+ + L KRK +A + L + + L L + + K+ Sbjct: 222 ELQEKLRLVESEKSEIQLNVKDL-KRKLERAQLLLPQQQLQVEADRLGKEL-QSVSAKLQ 279 Query: 117 FRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENE 176 + + N W + ++ E K++E+E E +I E+EE + R+E + Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKM------WRQEEK 333 Query: 177 LPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIE 236 + E + ++ K+ ++ ++ + E+++ ++E++ + Sbjct: 334 M---------------------HEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQ 372 Query: 237 KERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENE---LGQGEKSMLQPQDI 293 +E++R D E++Q ++E + + EK+R Q ++ E Q EK Q +++ Sbjct: 373 EEKIREQD---EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429 Query: 294 ETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 ++ K+ RE ++ +D+ + L+ EK+Q E+E++Q ++++++ Q+E Sbjct: 430 WRQEEKI-RELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEE 476 Score = 49.7 bits (117), Expect = 4e-06 Identities = 53/232 (22%), Positives = 114/232 (49%), Gaps = 32/232 (13%) Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169 E +EKI R W+ R+ + K++E+E + E +I E+EE + Sbjct: 357 EQEEKI--REQEEKMWRQEEKIREQ-----DEKIQEQEEEMWRQEEKIREQEEKRQEKM- 408 Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229 R+E ++ + ++ + E++ ELE+ D E E+L+ Sbjct: 409 -WRQEKKMRE-------------QDEKIREQEEEMWRQEEKIRELEEMMQDQE-EKLREV 453 Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ--IVNSEKPSLENE---LGQGE 284 +E++Q E+E+++ + E++Q ++E++Q + EK Q ++ E+ E E Q E Sbjct: 454 EEKMQEEEEKMQE---QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510 Query: 285 KSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336 K Q + ++ ++ K++R+ ++ + ++ + + EK+Q ++ RLQ ++RL Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQ-QEEKMQEQEVRLQELEERL 561 Score = 47.8 bits (112), Expect = 1e-05 Identities = 45/207 (21%), Positives = 107/207 (51%), Gaps = 18/207 (8%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K+ E+E E +I E+EE + R+ E DE + Sbjct: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE--KIREQDE--KIQEQEEEMWRQ 393 Query: 200 EPHLLVNIEK--QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL 257 E + EK +K+ +++++ + E+++ ++E + ++E++R L+ E +Q ++E+L Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE---EMMQDQEEKL 450 Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIET---EKLKLERERLQLEKDRLQF 314 + EK++ + EK + E Q ++ +Q Q+ +T EKL + E++ +++++ Sbjct: 451 REVEEKMQEE---EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507 Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341 + EK+ ++E++Q ++++++ Q+E Sbjct: 508 ---QEEKMWEQEEKMQEQEEKMQRQEE 531 Score = 41.2 bits (95), Expect = 0.001 Identities = 49/204 (24%), Positives = 93/204 (45%), Gaps = 38/204 (18%) Query: 164 LSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEA 223 L V R EN L ++E + Y E + E+ L LE R I Sbjct: 162 LGEVTAQKRPENSL-----LEETLHFDHAVRMGTYIEK---LTKERDALSLELYRNTITD 213 Query: 224 ERLQVEKERLQIEKERLRHLDMEHERLQLE----------------KERLQIEREKL--R 265 E L+ + LQ E+LR ++ E +QL +++LQ+E ++L Sbjct: 214 EELKEKNAELQ---EKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270 Query: 266 LQIVNSEKPSL--ENEL------GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317 LQ V+++ + ENEL Q EK Q + I+ ++ K+ + L++ + + + Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR- 329 Query: 318 ESEKLQIEKERLQVEKDRLRIQKE 341 + EK+ ++E+++ ++D++ Q+E Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEE 353 Score = 32.3 bits (72), Expect = 0.64 Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 12/152 (7%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDS-RRENELPDFPHIDEFFTLNSTPSRSAY 198 E K++EEE Q E +I+ +EE + + R+E L I E + Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMW 513 Query: 199 DEPHLLVNIEK------QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERL-- 250 ++ + E+ +K+ ++ RL + E++Q ++ RLQ +ERL L + E L Sbjct: 514 EQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573 Query: 251 ---QLEKERLQIEREKLRLQIVNSEKPSLENE 279 + +RL L++++ + E SL+ + Sbjct: 574 AGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 57.0 bits (136), Expect = 2e-08 Identities = 59/216 (27%), Positives = 104/216 (48%), Gaps = 20/216 (9%) Query: 132 RDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP--HIDEFFTL 189 ++ L KVEE++R + E +++ EE L V+ R ++ + I++ F Sbjct: 548 KEEAEQLRRQKVEEDKRR-RLEEVKLKREER-LRKVLQARERVEQMKEEKKKQIEQKFAQ 605 Query: 190 NSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKER----LQIEKERLRHLDM 245 + A +E L + +K K+ ++EA R Q E+ R LQ E+E RH ++ Sbjct: 606 IDEKTEKAKEER--LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 663 Query: 246 EHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERL 305 ++ + E+ERL+ E RL ++ E + E+ + + E E+ + ER+ Sbjct: 664 LQKKKEEEQERLRKAAEAKRLA---EQREQERREQERREQERREQERREQERREQERQLA 720 Query: 306 QLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 + E+ R E E+LQ E+E LQ + LR+QKE Sbjct: 721 EQERRR------EQERLQAERE-LQEREKALRLQKE 749 Score = 41.2 bits (95), Expect = 0.001 Identities = 39/144 (27%), Positives = 79/144 (54%), Gaps = 15/144 (10%) Query: 207 IEKQKLELEKRRLDIEAERLQVEK----ERLQIEK------ERLRHLDMEHERLQLEKER 256 +EK++ LE R EAE+L+ +K +R ++E+ ERLR + ER++ KE Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 594 Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316 + + E+ QI + + E L + EK+ + + E+++ R++ + E RL++L+ Sbjct: 595 KKKQIEQKFAQIDEKTEKAKEERLAE-EKAKKKAAAKKMEEVEARRKQ-EEEARRLRWLQ 652 Query: 317 FESEK---LQIEKERLQVEKDRLR 337 E E+ ++ +++ + E++RLR Sbjct: 653 QEEEERRHQELLQKKKEEEQERLR 676 Score = 41.2 bits (95), Expect = 0.001 Identities = 53/195 (27%), Positives = 85/195 (43%), Gaps = 21/195 (10%) Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169 +IDEK + + A + A + EV+ ++ + +++EEE Sbjct: 605 QIDEKTEKAKEERLA-EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE------- 656 Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229 RR EL +E L E E+++ E E+R + E+ + E Sbjct: 657 -ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE-RREQERRE 714 Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQ 289 +ER E+ER R E ERLQ E+E LQ + LRLQ K L+ EL + +K Q Sbjct: 715 QERQLAEQERRR----EQERLQAERE-LQEREKALRLQ-----KEQLQRELEEKKKKEEQ 764 Query: 290 PQDIETEKLKLERER 304 Q + +L+ E+E+ Sbjct: 765 -QRLAERQLQEEQEK 778 Score = 38.9 bits (89), Expect = 0.007 Identities = 40/156 (25%), Positives = 72/156 (46%), Gaps = 16/156 (10%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSR----RENELPDFPHIDEFFTLNSTPSRSAYD 199 EEE R + + + EEE+E L R RE E + ++ + + Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 714 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259 + E+Q E E+RR E ERLQ E+E LQ E+E+ L E + +LE+++ + Sbjct: 715 Q-------ERQLAEQERRR---EQERLQAERE-LQ-EREKALRLQKEQLQRELEEKKKKE 762 Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIET 295 E+++L + + E+ E K++ D+++ Sbjct: 763 EQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 798 Score = 38.1 bits (87), Expect = 0.012 Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 25/137 (18%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ----------LEKERL 257 +K++ E E+ R EA+RL ++E+ + E+ER E ER + E+ER Sbjct: 666 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER- 724 Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSM-LQPQDIETEKLKLERERLQLEKDRLQFLK 316 RE+ RLQ E EL + EK++ LQ + ++ E LE ++ + E+ RL + Sbjct: 725 --RREQERLQ--------AERELQEREKALRLQKEQLQRE---LEEKKKKEEQQRLAERQ 771 Query: 317 FESEKLQIEKERLQVEK 333 + E+ + KE K Sbjct: 772 LQEEQEKKAKEAAGASK 788 Score = 30.8 bits (68), Expect = 1.9 Identities = 23/87 (26%), Positives = 47/87 (54%), Gaps = 11/87 (12%) Query: 265 RLQIVNSEKPSLENELGQGEKSMLQPQDIETEK------LKLERE----RLQLEKDRLQF 314 + V E+ LEN + E L+ Q +E +K +KL+RE ++ ++R++ Sbjct: 531 KCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQ 590 Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341 +K E +K QIE++ Q+++ + ++E Sbjct: 591 MK-EEKKKQIEQKFAQIDEKTEKAKEE 616 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 57.0 bits (136), Expect = 2e-08 Identities = 59/216 (27%), Positives = 104/216 (48%), Gaps = 20/216 (9%) Query: 132 RDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP--HIDEFFTL 189 ++ L KVEE++R + E +++ EE L V+ R ++ + I++ F Sbjct: 544 KEEAEQLRRQKVEEDKRR-RLEEVKLKREER-LRKVLQARERVEQMKEEKKKQIEQKFAQ 601 Query: 190 NSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKER----LQIEKERLRHLDM 245 + A +E L + +K K+ ++EA R Q E+ R LQ E+E RH ++ Sbjct: 602 IDEKTEKAKEER--LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 659 Query: 246 EHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERL 305 ++ + E+ERL+ E RL ++ E + E+ + + E E+ + ER+ Sbjct: 660 LQKKKEEEQERLRKAAEAKRLA---EQREQERREQERREQERREQERREQERREQERQLA 716 Query: 306 QLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 + E+ R E E+LQ E+E LQ + LR+QKE Sbjct: 717 EQERRR------EQERLQAERE-LQEREKALRLQKE 745 Score = 41.2 bits (95), Expect = 0.001 Identities = 53/195 (27%), Positives = 85/195 (43%), Gaps = 21/195 (10%) Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169 +IDEK + + A + A + EV+ ++ + +++EEE Sbjct: 601 QIDEKTEKAKEERLA-EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE------- 652 Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229 RR EL +E L E E+++ E E+R + E+ + E Sbjct: 653 -ERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE-RREQERRE 710 Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQ 289 +ER E+ER R E ERLQ E+E LQ + LRLQ K L+ EL + +K Q Sbjct: 711 QERQLAEQERRR----EQERLQAERE-LQEREKALRLQ-----KEQLQRELEEKKKKEEQ 760 Query: 290 PQDIETEKLKLERER 304 Q + +L+ E+E+ Sbjct: 761 -QRLAERQLQEEQEK 774 Score = 40.0 bits (92), Expect = 0.003 Identities = 39/143 (27%), Positives = 78/143 (54%), Gaps = 15/143 (10%) Query: 208 EKQKLELEKRRLDIEAERLQVEK----ERLQIEK------ERLRHLDMEHERLQLEKERL 257 EK++ LE R EAE+L+ +K +R ++E+ ERLR + ER++ KE Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 591 Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317 + + E+ QI + + E L + EK+ + + E+++ R++ + E RL++L+ Sbjct: 592 KKQIEQKFAQIDEKTEKAKEERLAE-EKAKKKAAAKKMEEVEARRKQ-EEEARRLRWLQQ 649 Query: 318 ESEK---LQIEKERLQVEKDRLR 337 E E+ ++ +++ + E++RLR Sbjct: 650 EEEERRHQELLQKKKEEEQERLR 672 Score = 38.9 bits (89), Expect = 0.007 Identities = 40/156 (25%), Positives = 72/156 (46%), Gaps = 16/156 (10%) Query: 144 EEEERDPQSPEFEIEEEEEMLSSVIPDSR----RENELPDFPHIDEFFTLNSTPSRSAYD 199 EEE R + + + EEE+E L R RE E + ++ + + Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 710 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259 + E+Q E E+RR E ERLQ E+E LQ E+E+ L E + +LE+++ + Sbjct: 711 Q-------ERQLAEQERRR---EQERLQAERE-LQ-EREKALRLQKEQLQRELEEKKKKE 758 Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIET 295 E+++L + + E+ E K++ D+++ Sbjct: 759 EQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 794 Score = 38.1 bits (87), Expect = 0.012 Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 25/137 (18%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQ----------LEKERL 257 +K++ E E+ R EA+RL ++E+ + E+ER E ER + E+ER Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER- 720 Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSM-LQPQDIETEKLKLERERLQLEKDRLQFLK 316 RE+ RLQ E EL + EK++ LQ + ++ E LE ++ + E+ RL + Sbjct: 721 --RREQERLQ--------AERELQEREKALRLQKEQLQRE---LEEKKKKEEQQRLAERQ 767 Query: 317 FESEKLQIEKERLQVEK 333 + E+ + KE K Sbjct: 768 LQEEQEKKAKEAAGASK 784 Score = 31.2 bits (69), Expect = 1.4 Identities = 24/88 (27%), Positives = 48/88 (54%), Gaps = 11/88 (12%) Query: 264 LRLQIVNSEKPSLENELGQGEKSMLQPQDIETEK------LKLERE----RLQLEKDRLQ 313 LR+ E+ LEN + E L+ Q +E +K +KL+RE ++ ++R++ Sbjct: 526 LRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVE 585 Query: 314 FLKFESEKLQIEKERLQVEKDRLRIQKE 341 +K E +K QIE++ Q+++ + ++E Sbjct: 586 QMK-EEKKKQIEQKFAQIDEKTEKAKEE 612 >gi|7661936 scaffold attachment factor B2 [Homo sapiens] Length = 953 Score = 56.2 bits (134), Expect = 4e-08 Identities = 56/211 (26%), Positives = 105/211 (49%), Gaps = 29/211 (13%) Query: 139 TEVKVEE--EERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRS 196 T +K EE E+++ + PE +I++EE+ + P + + T+ S+ Sbjct: 521 TVIKKEEKIEKKEEKKPE-DIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKG 579 Query: 197 AYDEPHLLVNIEKQKLELEKRRLDIEAER------LQVEKERLQIEKERLRHLDMEHERL 250 EP + V + E + D ++E L +K + Q E+ER R + E Sbjct: 580 ---EPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRET 636 Query: 251 QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKD 310 + +ER Q ERE+ RL+ + K EK+ LQ E+L+LE +R +LE++ Sbjct: 637 ERRREREQREREQ-RLEAFHERK----------EKARLQ-----RERLQLECQRQRLERE 680 Query: 311 RLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 R++ + E E++++E+ER + E++R+ ++E Sbjct: 681 RMERERLERERMRVERER-RKEQERIHRERE 710 Score = 47.8 bits (112), Expect = 1e-05 Identities = 37/140 (26%), Positives = 72/140 (51%), Gaps = 15/140 (10%) Query: 139 TEVKVEEEERDPQSPEFEIEEEEEMLS-SVIPDSR-------RENELPDFPHIDEFFTLN 190 T + +E Q + E +E+ ++LS I + R RE E+ + E Sbjct: 587 TTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQRE 646 Query: 191 STPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQ---VEKERLQIEKERLRHLDMEH 247 A+ E +++++L+LE +R +E ER++ +E+ER+++E+ER + E Sbjct: 647 REQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRK----EQ 702 Query: 248 ERLQLEKERLQIEREKLRLQ 267 ER+ E+E L+ ++E+LR + Sbjct: 703 ERIHREREELRRQQEQLRYE 722 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 55.5 bits (132), Expect = 7e-08 Identities = 53/265 (20%), Positives = 127/265 (47%), Gaps = 35/265 (13%) Query: 80 MKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGGSLT 139 +KRK +A + L + + L L + + K+ + + N W + ++ Sbjct: 244 LKRKLERAQLLLPQQQLQVEADRLGKEL-QSVSAKLQAQVEENELWNLLNQQQEEKMWRQ 302 Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K++E+E E +I E+EE + R+E ++ Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKM------WRQEEKM---------------------H 335 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259 E + ++ K+ ++ ++ + E+++ ++E++ ++E++R D E++Q ++E + Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD---EKIQEQEEEMWR 392 Query: 260 EREKLRLQIVNSEKPSLENE---LGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316 + EK+R Q ++ E Q EK Q +++ ++ K+ RE ++ +D+ + L+ Sbjct: 393 QEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI-RELEEMMQDQEEKLR 451 Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341 EK+Q E+E++Q ++++++ Q+E Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEE 476 Score = 49.7 bits (117), Expect = 4e-06 Identities = 53/232 (22%), Positives = 114/232 (49%), Gaps = 32/232 (13%) Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169 E +EKI R W+ R+ + K++E+E + E +I E+EE + Sbjct: 357 EQEEKI--REQEEKMWRQEEKIREQ-----DEKIQEQEEEMWRQEEKIREQEEKRQEKM- 408 Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVE 229 R+E ++ + ++ + E++ ELE+ D E E+L+ Sbjct: 409 -WRQEKKMRE-------------QDEKIREQEEEMWRQEEKIRELEEMMQDQE-EKLREV 453 Query: 230 KERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ--IVNSEKPSLENE---LGQGE 284 +E++Q E+E+++ + E++Q ++E++Q + EK Q ++ E+ E E Q E Sbjct: 454 EEKMQEEEEKMQE---QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510 Query: 285 KSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRL 336 K Q + ++ ++ K++R+ ++ + ++ + + EK+Q ++ RLQ ++RL Sbjct: 511 KMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQ-QEEKMQEQEVRLQELEERL 561 Score = 49.3 bits (116), Expect = 5e-06 Identities = 36/170 (21%), Positives = 96/170 (56%), Gaps = 27/170 (15%) Query: 199 DEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERL-------------QIEKERLRHL-- 243 ++ + +N++ K +LE+ +L + ++LQVE +RL Q+E+ L +L Sbjct: 233 EKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLN 292 Query: 244 DMEHERLQLEKERLQIEREKL---RLQIVNSEKPSL--ENELGQGEKSMLQPQDI---ET 295 + E++ ++E++Q + EK+ L+I E+ E ++ + E+ + + +D + Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352 Query: 296 EKLKLERERLQLEKDRL----QFLKFESEKLQIEKERLQVEKDRLRIQKE 341 EK++ + E+++ +++++ + ++ + EK+Q ++E + +++++R Q+E Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402 Score = 47.8 bits (112), Expect = 1e-05 Identities = 45/207 (21%), Positives = 107/207 (51%), Gaps = 18/207 (8%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K+ E+E E +I E+EE + R+ E DE + Sbjct: 338 EEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEE--KIREQDE--KIQEQEEEMWRQ 393 Query: 200 EPHLLVNIEK--QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERL 257 E + EK +K+ +++++ + E+++ ++E + ++E++R L+ E +Q ++E+L Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE---EMMQDQEEKL 450 Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIET---EKLKLERERLQLEKDRLQF 314 + EK++ + EK + E Q ++ +Q Q+ +T EKL + E++ +++++ Sbjct: 451 REVEEKMQEE---EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507 Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341 + EK+ ++E++Q ++++++ Q+E Sbjct: 508 ---QEEKMWEQEEKMQEQEEKMQRQEE 531 Score = 38.5 bits (88), Expect = 0.009 Identities = 48/204 (23%), Positives = 92/204 (45%), Gaps = 38/204 (18%) Query: 164 LSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEA 223 L V R EN L ++E + Y E + E+ LE R I Sbjct: 162 LGEVTAQKRPENSL-----LEETLHFDHAVRMGTYIEK---LTKERDAPSLELYRNTITD 213 Query: 224 ERLQVEKERLQIEKERLRHLDMEHERLQLE----------------KERLQIEREKL--R 265 E L+ + LQ E+LR ++ E +QL +++LQ+E ++L Sbjct: 214 EELKEKNAELQ---EKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270 Query: 266 LQIVNSEKPSL--ENEL------GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317 LQ V+++ + ENEL Q EK Q + I+ ++ K+ + L++ + + + Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR- 329 Query: 318 ESEKLQIEKERLQVEKDRLRIQKE 341 + EK+ ++E+++ ++D++ Q+E Sbjct: 330 QEEKMHEQEEKIREQEDKMWRQEE 353 Score = 32.3 bits (72), Expect = 0.64 Identities = 36/152 (23%), Positives = 69/152 (45%), Gaps = 12/152 (7%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDS-RRENELPDFPHIDEFFTLNSTPSRSAY 198 E K++EEE Q E +I+ +EE + + R+E L I E + Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMW 513 Query: 199 DEPHLLVNIEK------QKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERL-- 250 ++ + E+ +K+ ++ RL + E++Q ++ RLQ +ERL L + E L Sbjct: 514 EQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573 Query: 251 ---QLEKERLQIEREKLRLQIVNSEKPSLENE 279 + +RL L++++ + E SL+ + Sbjct: 574 AGRESGSQRLPTLTPILQVELKSQEAQSLQQQ 605 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 55.5 bits (132), Expect = 7e-08 Identities = 45/205 (21%), Positives = 99/205 (48%), Gaps = 4/205 (1%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E +EE+ + + +EIEE E + S + R+ E ++ P R + Sbjct: 145 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 204 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD--MEHERLQLE-KER 256 E + V +E++ E ++ + + + Q+ E + E+ER + D HE+++ E KER Sbjct: 205 ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKER 264 Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316 + ER +L + K + ++ E++ ++ ++ + + RE + E+ R + + Sbjct: 265 AEAERARLEAEERERIKAEQDKKIAD-ERARIEAEEKAAAQERERREAEERERMREEEKR 323 Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341 E+ +I++E + ++R RI++E Sbjct: 324 AAEERQRIKEEEKRAAEERQRIKEE 348 Score = 48.9 bits (115), Expect = 7e-06 Identities = 54/234 (23%), Positives = 101/234 (43%), Gaps = 31/234 (13%) Query: 130 DFRDAGGSLTEVKVEEEERDPQSPEFEI--------------EEEEEMLSSVIPDSRREN 175 D+RDA + E K +EEE + + I E +EE + + + + + Sbjct: 176 DWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISS 235 Query: 176 ELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRR-------LDIEAERLQV 228 E P E + + +E E+ +LE E+R I ER ++ Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARI 295 Query: 229 EKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLE--NELGQGEKS 286 E E +ER R E ER++ E++R ER++++ EK + E + + EK Sbjct: 296 EAEEKAAAQERERREAEERERMREEEKRAAEERQRIK----EEEKRAAEERQRIKEEEKR 351 Query: 287 MLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQK 340 + E +++K E +R E+ R + + E K++ +K Q+E+ + +Q+ Sbjct: 352 AAE----ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE 401 Score = 44.3 bits (103), Expect = 2e-04 Identities = 43/195 (22%), Positives = 95/195 (48%), Gaps = 17/195 (8%) Query: 142 KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEP 201 K+ +E ++ E +E E + + RE E +E + R+A E Sbjct: 287 KIADERARIEAEEKAAAQERERREAEERERMREEEKRA---AEERQRIKEEEKRAA--EE 341 Query: 202 HLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIER 261 + E+++ E++R+ E +R E++R + E+E ++ + QLE+++ ++ Sbjct: 342 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE 401 Query: 262 EKLRLQIVN--------SEKPSLENELGQGEKSMLQPQDIET-EKLKLERERLQLEKDRL 312 K++ + V +EK + E++L + ++L+ Q E K++ +RE+LQ +K Sbjct: 402 TKIKGEKVEQKIEGKWVNEKKAQEDKL---QTAVLKKQGEEKGTKVQAKREKLQEDKPTF 458 Query: 313 QFLKFESEKLQIEKE 327 + + + EK++ +KE Sbjct: 459 KKEEIKDEKIKKDKE 473 Score = 36.2 bits (82), Expect = 0.044 Identities = 69/356 (19%), Positives = 140/356 (39%), Gaps = 56/356 (15%) Query: 2 KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61 ++ +R R+ E + +KE KR + + I ++ A EE + + E Sbjct: 312 EERERMREEEKRAAEERQRIKEEEKR-----AAEERQRIKEEEKRAAEERQR----IKEE 362 Query: 62 EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLD-DSLTEEIDEKIGFRND 120 E+R E +R + K + K N +L + + + + + ++I+ K Sbjct: 363 EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK 422 Query: 121 ANFDWQNVADFRDAGGSL-TEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPD 179 A D A + G T+V+ + E+ P F+ EE ++ + D + E+ Sbjct: 423 AQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKD--EKIKKDKEPKEEVKS 480 Query: 180 F-----------PHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEA-ERLQ 227 F EF T + + + P +++ ++ E + +EA +RL+ Sbjct: 481 FMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ---VEAGKRLE 537 Query: 228 -VEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKS 286 + + R + E E L + + LE E L+ +RE+ R + E+ + E + Sbjct: 538 ELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADR---- 593 Query: 287 MLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKEG 342 KL+ E E+ +L K +IE+ R + + R ++ ++G Sbjct: 594 ----------KLREEEEKRRL-------------KEEIERRRAEAAEKRQKMPEDG 626 Score = 33.1 bits (74), Expect = 0.37 Identities = 65/286 (22%), Positives = 111/286 (38%), Gaps = 45/286 (15%) Query: 7 KRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEGEQRTG 66 ++K N ++E + ++E + E + K +N K A E+ Q +GE++ G Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKK--AQEDKLQTAVLKKQGEEK-G 441 Query: 67 TEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEI-DEKIGFRNDANFDW 125 T+V+ KR++++ D EEI DEKI + Sbjct: 442 TKVQA---------KREKLQ--------------EDKPTFKKEEIKDEKIKKDKEPK--- 475 Query: 126 QNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRE---NELPDFPH 182 + V F D TEVK + E +++ E S P R E P Sbjct: 476 EEVKSFMDRKKGFTEVKSQNGE----FMTHKLKHTENTFSR--PGGRASVDTKEAEGAPQ 529 Query: 183 IDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRH 242 ++ L R E EK K + ++ L++E + + E+ R +E+E R Sbjct: 530 VEAGKRLEELRRRRGETESE---EFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRR 586 Query: 243 LDMEHERL---QLEKERLQIEREKLRLQIVNSEKPSLENELGQGEK 285 E +R + EK RL+ E E+ R + + E+ L +K Sbjct: 587 KQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632 >gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] Length = 1173 Score = 54.3 bits (129), Expect = 2e-07 Identities = 53/225 (23%), Positives = 110/225 (48%), Gaps = 29/225 (12%) Query: 126 QNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENE-LPDFPHID 184 Q++ D ++ K++ RD Q + +IEE+E +L +++P+ L D ++ Sbjct: 598 QSIIDLKEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIME 657 Query: 185 EF-FTLNSTPSRSAYDEPHLL----------VNIEKQKLELEKRRLDIEAERLQVEKERL 233 F L + A L VN EKQ+ ++ +LD + ++++ ++ + Sbjct: 658 RFQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQE---KQHKLDTVSSKIELNRKLI 714 Query: 234 QIEKERLRHL-----DMEHERLQLE---KERLQIEREKLRLQIVNSEKPSLENELGQGEK 285 Q ++E+++HL +++ E+LQ+ + R Q+E + + L ++E SL E+ + K Sbjct: 715 QDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVEL---STEVQSLYREI-KDAK 770 Query: 286 SMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQ 330 + P + EK + E+E L +K+ K +KL KE+++ Sbjct: 771 EQVSPLETTLEKFQQEKEELINKKNTSN--KIAQDKLNDIKEKVK 813 Score = 39.3 bits (90), Expect = 0.005 Identities = 59/249 (23%), Positives = 108/249 (43%), Gaps = 50/249 (20%) Query: 141 VKVEEEERDPQSPEFEIEEEEEMLSSVIP--------DSRRENELPDFPHIDEFFT---- 188 VK E E DP ++E E LS ++ DSR++ D ++E Sbjct: 102 VKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQ 159 Query: 189 --------LNSTPSRSAYDEPHLLVNI--EKQKLELEKRRLDIEAERLQVEKERLQIE-- 236 L R+ ++ LV+ E +KL E R L+ E L VE+ RLQ++ Sbjct: 160 GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQAD 219 Query: 237 --KERLRHLDMEHERLQLEKERLQIEREKL-RLQIVNSEKPSLENELGQ----------- 282 +E +R D + L + E ER QI N K E + G+ Sbjct: 220 RHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDF 279 Query: 283 GEKSMLQPQDIETEK---------LKLERERLQLEKDRLQFLKFESEKLQIEKER-LQVE 332 EK L+ + I+ + ++L+ E L +++ L+ +K+E ++L+ +R L+++ Sbjct: 280 AEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELD 339 Query: 333 KDRLRIQKE 341 ++ ++ ++E Sbjct: 340 QELIKAERE 348 Score = 35.8 bits (81), Expect = 0.058 Identities = 29/143 (20%), Positives = 73/143 (51%), Gaps = 7/143 (4%) Query: 201 PHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERLQLEKERL 257 P L ++ ++++ + DIE + + + E ++ D ME +++L+ Sbjct: 609 PELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVER 668 Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317 +I ++ +LQ ++ ++ ++ Q ++ D + K++L R+ +Q +++++Q LK Sbjct: 669 KIAQQAAKLQGIDLDRTV--QQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKS 726 Query: 318 ESEKLQIEKERLQVEKDRLRIQK 340 + +L+ EK LQ+ + R Q+ Sbjct: 727 TTNELKSEK--LQISTNLQRRQQ 747 Score = 30.4 bits (67), Expect = 2.4 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 4/71 (5%) Query: 263 KLRLQIVNSEKPSLEN---ELGQGEKSMLQPQDIETEKLKLERERLQLEKD-RLQFLKFE 318 +L+ +I++ ++ L+N EL Q E S + +++ E +K ERE + EK+ ++ LK E Sbjct: 305 ELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKME 364 Query: 319 SEKLQIEKERL 329 LQ EK L Sbjct: 365 VISLQNEKADL 375 >gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] Length = 1312 Score = 54.3 bits (129), Expect = 2e-07 Identities = 53/225 (23%), Positives = 110/225 (48%), Gaps = 29/225 (12%) Query: 126 QNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENE-LPDFPHID 184 Q++ D ++ K++ RD Q + +IEE+E +L +++P+ L D ++ Sbjct: 737 QSIIDLKEKEIPELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIME 796 Query: 185 EF-FTLNSTPSRSAYDEPHLL----------VNIEKQKLELEKRRLDIEAERLQVEKERL 233 F L + A L VN EKQ+ ++ +LD + ++++ ++ + Sbjct: 797 RFQMELKDVERKIAQQAAKLQGIDLDRTVQQVNQEKQE---KQHKLDTVSSKIELNRKLI 853 Query: 234 QIEKERLRHL-----DMEHERLQLE---KERLQIEREKLRLQIVNSEKPSLENELGQGEK 285 Q ++E+++HL +++ E+LQ+ + R Q+E + + L ++E SL E+ + K Sbjct: 854 QDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVEL---STEVQSLYREI-KDAK 909 Query: 286 SMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQ 330 + P + EK + E+E L +K+ K +KL KE+++ Sbjct: 910 EQVSPLETTLEKFQQEKEELINKKNTSN--KIAQDKLNDIKEKVK 952 Score = 39.3 bits (90), Expect = 0.005 Identities = 59/249 (23%), Positives = 108/249 (43%), Gaps = 50/249 (20%) Query: 141 VKVEEEERDPQSPEFEIEEEEEMLSSVIP--------DSRRENELPDFPHIDEFFT---- 188 VK E E DP ++E E LS ++ DSR++ D ++E Sbjct: 241 VKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQ 298 Query: 189 --------LNSTPSRSAYDEPHLLVNI--EKQKLELEKRRLDIEAERLQVEKERLQIE-- 236 L R+ ++ LV+ E +KL E R L+ E L VE+ RLQ++ Sbjct: 299 GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQAD 358 Query: 237 --KERLRHLDMEHERLQLEKERLQIEREKL-RLQIVNSEKPSLENELGQ----------- 282 +E +R D + L + E ER QI N K E + G+ Sbjct: 359 RHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDF 418 Query: 283 GEKSMLQPQDIETEK---------LKLERERLQLEKDRLQFLKFESEKLQIEKER-LQVE 332 EK L+ + I+ + ++L+ E L +++ L+ +K+E ++L+ +R L+++ Sbjct: 419 AEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQQLEGSSDRILELD 478 Query: 333 KDRLRIQKE 341 ++ ++ ++E Sbjct: 479 QELIKAERE 487 Score = 35.8 bits (81), Expect = 0.058 Identities = 29/143 (20%), Positives = 73/143 (51%), Gaps = 7/143 (4%) Query: 201 PHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERLQLEKERL 257 P L ++ ++++ + DIE + + + E ++ D ME +++L+ Sbjct: 748 PELRNKLQNVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVER 807 Query: 258 QIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKF 317 +I ++ +LQ ++ ++ ++ Q ++ D + K++L R+ +Q +++++Q LK Sbjct: 808 KIAQQAAKLQGIDLDRTV--QQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKS 865 Query: 318 ESEKLQIEKERLQVEKDRLRIQK 340 + +L+ EK LQ+ + R Q+ Sbjct: 866 TTNELKSEK--LQISTNLQRRQQ 886 Score = 30.4 bits (67), Expect = 2.4 Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 4/71 (5%) Query: 263 KLRLQIVNSEKPSLEN---ELGQGEKSMLQPQDIETEKLKLERERLQLEKD-RLQFLKFE 318 +L+ +I++ ++ L+N EL Q E S + +++ E +K ERE + EK+ ++ LK E Sbjct: 444 ELKSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKME 503 Query: 319 SEKLQIEKERL 329 LQ EK L Sbjct: 504 VISLQNEKADL 514 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 54.3 bits (129), Expect = 2e-07 Identities = 51/202 (25%), Positives = 103/202 (50%), Gaps = 21/202 (10%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K+ EEER + E ++ EEEEM+ RE E + E ++ Sbjct: 582 EEKMREEER-MREREKKMREEEEMM--------REQE----EKMQEQEEKMQEQEEKMWE 628 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQI 259 + + E++ E E++ E E E++RL +KE+L EHE++Q E+E++Q Sbjct: 629 QEEKMQEQEEKMWEQEEKMW--EQEEKMWEQQRLPEQKEKL----WEHEKMQ-EQEKMQE 681 Query: 260 EREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFES 319 + EK+ Q EK + E E ++ ++ ++ E+ K RE ++ +++ + ++ + Sbjct: 682 QEEKIWEQ-EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQE 740 Query: 320 EKLQIEKERLQVEKDRLRIQKE 341 EK+Q ++E + +++++ Q+E Sbjct: 741 EKMQEQEEEMWEQEEKMWEQEE 762 Score = 50.8 bits (120), Expect = 2e-06 Identities = 49/207 (23%), Positives = 106/207 (51%), Gaps = 27/207 (13%) Query: 142 KVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYDEP 201 K++E+E E +I ++EEM R+E + E + +D+ Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564 Query: 202 HLLVNIEKQKLELEKRRLD-----IEAERLQVEKERLQIEKERLRHLDMEHERLQLEKER 256 +EK+ E EK+ D E ER++ +++++ E+E +R + E++Q ++E+ Sbjct: 565 E---RMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE---QEEKMQEQEEK 618 Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQD--IETEKLKLERERLQLEKDRLQF 314 +Q + EK+ Q E ++ + E+ M + ++ E E+ E++RL +K++L Sbjct: 619 MQEQEEKMWEQ---------EEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL-- 667 Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341 +E EK+Q E+E++Q +++++ Q++ Sbjct: 668 --WEHEKMQ-EQEKMQEQEEKIWEQEK 691 Score = 48.9 bits (115), Expect = 7e-06 Identities = 48/205 (23%), Positives = 104/205 (50%), Gaps = 15/205 (7%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K++E+E Q E ++ E+EE + + E E + ++ + P + Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQ-EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667 Query: 200 EPHLLVNIEKQKLELEKRRLDIEA-ERLQVEKERLQIEKERLRHLDM--EHERLQLEKER 256 H + +++ E E++ + E E+ E+E+ ++E++R + E E+ E+E Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727 Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316 + E+E+ ++Q + E E+ + E+ M E E+ E++RL +K++L Sbjct: 728 MMREQEE-KMQEQEEKMQEQEEEMWEQEEKMW-----EQEEKMWEQQRLPEQKEKL---- 777 Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341 +E EK+Q E+E++ +++++R Q+E Sbjct: 778 WEHEKMQ-EQEKIWEQEEKMRDQEE 801 Score = 47.8 bits (112), Expect = 1e-05 Identities = 57/249 (22%), Positives = 124/249 (49%), Gaps = 32/249 (12%) Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169 E +EK+ + + ++ Q + + ++ L E + +E+ Q E +I E+E+M Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKE---KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT-- 696 Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEA------ 223 +E + D + E ++ + +E + EK + + EK + E Sbjct: 697 -QEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755 Query: 224 -----ERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLEN 278 E E++RL +KE+L EHE++Q E+E++ + EK+R Q EK + Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKL----WEHEKMQ-EQEKIWEQEEKMRDQ---EEKMRGQE 807 Query: 279 ELGQGEKSMLQPQDI----ETEKLKLERERLQLEKDRL--QFLKFESEKLQIEKERLQVE 332 E +G++ ++ Q+ + EK+ + E++ +++++ Q K E EK+Q ++E+++ + Sbjct: 808 EKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME-EKMQGQEEKMREQ 866 Query: 333 KDRLRIQKE 341 ++++R Q+E Sbjct: 867 EEKMRGQEE 875 Score = 47.4 bits (111), Expect = 2e-05 Identities = 48/227 (21%), Positives = 110/227 (48%), Gaps = 32/227 (14%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K+ E+E E + E+E+ L + R + EL + + Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMR 365 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERL--QLEK 254 E + ++++L +++++ + ++++ ++ER+ + ERLR + E E++ Q+EK Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425 Query: 255 ----ERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDI----------------E 294 +++Q + +K R Q EK E + + EK M + ++ E Sbjct: 426 MREEKKMQEQEKKTRDQ---EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482 Query: 295 TEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 E+ + +++RL +K++L +E EK+Q ++E++ +++++R Q+E Sbjct: 483 QEEKEWQQQRLPEQKEKL----WEQEKMQEQEEKIWEQEEKIRDQEE 525 Score = 45.8 bits (107), Expect = 6e-05 Identities = 52/271 (19%), Positives = 125/271 (46%), Gaps = 60/271 (22%) Query: 109 EEIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVI 168 E + EK + W+ V R+ E K++E+E+ + E +++EEE + Sbjct: 404 ERLREKEERMREQEKMWEQVEKMRE------EKKMQEQEKKTRDQEEKMQEEERI----- 452 Query: 169 PDSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEK----QKLELEKRRLDIEAE 224 RE ++ + E T+ + E ++ EK Q+L +K +L E E Sbjct: 453 --REREKKMRE-----EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL-WEQE 504 Query: 225 RLQVEKERLQIEKERLRHLD---------MEHERLQLEKERLQIEREKLRLQIVN----- 270 ++Q ++E++ ++E++R + E+++ +++++ + EK+R Q Sbjct: 505 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 564 Query: 271 -----------------SEKPSLENELGQGEKSMLQPQDI---ETEKLKLERERLQLEKD 310 EK E + + EK M + +++ + EK++ + E++Q +++ Sbjct: 565 ERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624 Query: 311 RLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 ++ + EK+Q ++E++ +++++ Q+E Sbjct: 625 KMWE---QEEKMQEQEEKMWEQEEKMWEQEE 652 Score = 45.8 bits (107), Expect = 6e-05 Identities = 42/209 (20%), Positives = 95/209 (45%), Gaps = 35/209 (16%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K +E+E+ E ++ EEE M RE E Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERM---------RERE-------------------KKMR 599 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD---MEHERLQLEKER 256 E ++ +++K++ ++ ++ + E++ ++E++Q ++E++ + E E E++R Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659 Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316 L ++EKL EK + ++ + E+ + + + +E + + E++ EK R + Sbjct: 660 LPEQKEKLW----EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715 Query: 317 FESEKLQIEKERLQVEKDRLRIQKEGHLQ 345 E EK E+E + E++ ++E +Q Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQ 744 Score = 45.1 bits (105), Expect = 1e-04 Identities = 36/136 (26%), Positives = 88/136 (64%), Gaps = 14/136 (10%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIEREKLRLQ 267 E+Q+L +K +L E E++Q E+E++ ++E++R + E+++ ++E+++ + EK+R Q Sbjct: 766 EQQRLPEQKEKL-WEHEKMQ-EQEKIWEQEEKMRD---QEEKMRGQEEKMRGQEEKMRGQ 820 Query: 268 IVNSEKPSLENEL--GQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIE 325 EK + E GQ EK Q + + ++ K+E E++Q +++++ + + EK++ + Sbjct: 821 ---EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME-EKMQGQEEKM---REQEEKMRGQ 873 Query: 326 KERLQVEKDRLRIQKE 341 +E+++ +++++R Q+E Sbjct: 874 EEKMREQEEKMRGQEE 889 Score = 42.4 bits (98), Expect = 6e-04 Identities = 43/207 (20%), Positives = 108/207 (52%), Gaps = 9/207 (4%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDF--PHIDEFFTLNSTPSRSA 197 E+K + E + P E E+ E L+ + + +R+ E F P + + TL R Sbjct: 222 ELKKKNAELQEKLPLAESEKSEIQLN--VKELKRKLERAKFLLPQV-QTNTLQEEMWRQE 278 Query: 198 YD--EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLE-K 254 + E + +++K+ ++ RL + +++ ++E++ +++RLR + E + E + Sbjct: 279 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338 Query: 255 ERLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQF 314 E+ ++ ++ ++Q + E ++ + E+ M + ++ E+ K RE+ Q +D+ + Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398 Query: 315 LKFESEKLQIEKERLQVEKDRLRIQKE 341 + + E+L+ ++ER++ E++++ Q E Sbjct: 399 MWEQDERLREKEERMR-EQEKMWEQVE 424 >gi|169208458 PREDICTED: similar to golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 432 Score = 54.3 bits (129), Expect = 2e-07 Identities = 52/140 (37%), Positives = 80/140 (57%), Gaps = 24/140 (17%) Query: 209 KQKLELEKRRLDIEAERLQV-------EKERLQIEKERLRHLDMEHERLQLEKERLQIER 261 +++LE R+L E E Q+ ++ERL+ ++ERLR + ERL ++ERL + Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLRE---QEERLCEQEERLCEQE 226 Query: 262 EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321 E+LR Q E+ E E G++ +L+ E EKL L++ER Q E++RL E E+ Sbjct: 227 ERLREQ----EERLCEQEKLPGQERLLE----EVEKL-LKQERRQEEQERL----LERER 273 Query: 322 LQIEKERLQVEKDRLRIQKE 341 L E E L +E++RLR Q E Sbjct: 274 LLDEVEEL-LEQERLRQQDE 292 Score = 46.6 bits (109), Expect = 3e-05 Identities = 43/143 (30%), Positives = 71/143 (49%), Gaps = 24/143 (16%) Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIERE 262 LL ++++L ++ RL + ERL ++ERL ++ERLR E+E E+E Sbjct: 192 LLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLR-----------EQEERLCEQE 240 Query: 263 KLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322 KL P E L + EK + Q + E ++ LERERL E + L E E+L Sbjct: 241 KL---------PGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEEL----LEQERL 287 Query: 323 QIEKERLQVEKDRLRIQKEGHLQ 345 + + ERL ++ +++ L+ Sbjct: 288 RQQDERLWQQETLRELERLRELE 310 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 54.3 bits (129), Expect = 2e-07 Identities = 65/325 (20%), Positives = 141/325 (43%), Gaps = 58/325 (17%) Query: 21 LKEITKRKEVIFSKQLNTTIN----VMKRMAWEEIAQCVNAVGEGEQRTGTEVKRRYLDW 76 ++E+TK ++ + + TI K +E Q V + Q E+KR+ Sbjct: 183 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 242 Query: 77 RALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDANFDWQNVADFRDAGG 136 + L+ +++++A +G S+ L + E N W + ++ Sbjct: 243 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE------------NELWNRLNQQQEEKM 290 Query: 137 SLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRS 196 E K++E E Q E +I E+EE + RR+ E+ Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKM-------RRQEEM------------------- 324 Query: 197 AYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKER 256 +++ + E+ E E++ ++E + + EK R Q EK + E E+ Q ++ + Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384 Query: 257 LQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLK 316 + + EK+R Q E + ++ M+Q Q+ EK+ + E++ +++ +Q Sbjct: 385 MWRQEEKIREQ----------EEKIREQEEMMQEQE---EKMGEQEEKMWEQEEEMQE-- 429 Query: 317 FESEKLQIEKERLQVEKDRLRIQKE 341 + EK++ ++E+++ ++ ++R Q+E Sbjct: 430 -QEEKMRRQEEKIREQEKKIREQEE 453 Score = 49.3 bits (116), Expect = 5e-06 Identities = 41/206 (19%), Positives = 109/206 (52%), Gaps = 26/206 (12%) Query: 140 EVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFPHIDEFFTLNSTPSRSAYD 199 E K+ +E + E +I E+EEM+ + E E + +E Sbjct: 382 EAKMWRQEEKIREQEEKIREQEEMMQEQ-EEKMGEQEEKMWEQEEEM------------Q 428 Query: 200 EPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD----MEHERLQLEKE 255 E + +++K+ +++++ + E+++ ++E +Q ++E++ + + ++Q ++E Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488 Query: 256 RLQIEREKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFL 315 +++ + EK+R Q +K + E + ++ M+Q Q+ EK+ + E++ +++++Q Sbjct: 489 KMRRQEEKIREQ---EKKIREQEEKIREQEEMMQEQE---EKMWEQEEKMCEQEEKMQE- 541 Query: 316 KFESEKLQIEKERLQVEKDRLRIQKE 341 + EK++ ++E+++ ++ RLR Q+E Sbjct: 542 --QEEKMRRQEEKMREQEVRLRQQEE 565 Score = 45.8 bits (107), Expect = 6e-05 Identities = 45/235 (19%), Positives = 113/235 (48%), Gaps = 20/235 (8%) Query: 110 EIDEKIGFRNDANFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIP 169 E +EK+ R W+ R+ + E + E+ + + E +I E+E+ Sbjct: 327 EKEEKM--RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384 Query: 170 DSRRENELPDFPHIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAE-RLQV 228 R+E ++ + ++ ++ E++ E E++ + E E + Q Sbjct: 385 MWRQEEKIRE-------------QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431 Query: 229 EKERLQIEK--ERLRHLDMEHERLQLEKERLQIEREKLRLQIVNSEKPSLENELGQGEKS 286 EK R Q EK E+ + + + E+++ ++E +Q + EK+ Q + E ++ + E+ Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ--EGKMCEQEAKMQEQEEK 489 Query: 287 MLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKLQIEKERLQVEKDRLRIQKE 341 M + ++ E+ K RE+ + +++ + ++ + EK+ ++E++ ++++++ Q+E Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 544 Score = 43.9 bits (102), Expect = 2e-04 Identities = 47/272 (17%), Positives = 119/272 (43%), Gaps = 33/272 (12%) Query: 2 KQLKRKRKSNFSVQETQTLLKEITKRKEVIFSKQLNTTINVMKRMAWEEIAQCVNAVGEG 61 ++++R+ + + +E +E+ KE + K EE Q + E Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375 Query: 62 EQRTGTEVKRRYLDWRALMKRKRMKANIKLVGSGFPLPSSDLDDSLTEEIDEKIGFRNDA 121 E+R E K WR K + + I+ + + +E +EK+G + + Sbjct: 376 EKRQEQEAKM----WRQEEKIREQEEKIRE------------QEEMMQEQEEKMGEQEEK 419 Query: 122 NFDWQNVADFRDAGGSLTEVKVEEEERDPQSPEFEIEEEEEMLSSVIPDSRRENELPDFP 181 ++ + ++ E K+ E+E+ + E +I E+EEM+ +E ++ + Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM------QEQEEKMGEQE 473 Query: 182 HIDEFFTLNSTPSRSAYDEPHLLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERL- 240 + E + +++K+ +++++ + E+++ ++E +Q ++E++ Sbjct: 474 G-------KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 526 Query: 241 ---RHLDMEHERLQLEKERLQIEREKLRLQIV 269 + + E++Q ++E+++ + EK+R Q V Sbjct: 527 EQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558 >gi|154937324 hypothetical protein LOC440295 [Homo sapiens] Length = 432 Score = 54.3 bits (129), Expect = 2e-07 Identities = 52/140 (37%), Positives = 80/140 (57%), Gaps = 24/140 (17%) Query: 209 KQKLELEKRRLDIEAERLQV-------EKERLQIEKERLRHLDMEHERLQLEKERLQIER 261 +++LE R+L E E Q+ ++ERL+ ++ERLR + ERL ++ERL + Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLRE---QEERLCEQEERLCEQE 226 Query: 262 EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321 E+LR Q E+ E E G++ +L+ E EKL L++ER Q E++RL E E+ Sbjct: 227 ERLREQ----EERLCEQEKLPGQERLLE----EVEKL-LKQERRQEEQERL----LERER 273 Query: 322 LQIEKERLQVEKDRLRIQKE 341 L E E L +E++RLR Q E Sbjct: 274 LLDEVEEL-LEQERLRQQDE 292 Score = 46.6 bits (109), Expect = 3e-05 Identities = 43/143 (30%), Positives = 71/143 (49%), Gaps = 24/143 (16%) Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIERE 262 LL ++++L ++ RL + ERL ++ERL ++ERLR E+E E+E Sbjct: 192 LLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLR-----------EQEERLCEQE 240 Query: 263 KLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322 KL P E L + EK + Q + E ++ LERERL E + L E E+L Sbjct: 241 KL---------PGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEEL----LEQERL 287 Query: 323 QIEKERLQVEKDRLRIQKEGHLQ 345 + + ERL ++ +++ L+ Sbjct: 288 RQQDERLWQQETLRELERLRELE 310 >gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sapiens] Length = 432 Score = 53.9 bits (128), Expect = 2e-07 Identities = 52/140 (37%), Positives = 79/140 (56%), Gaps = 24/140 (17%) Query: 209 KQKLELEKRRLDIEAERLQV-------EKERLQIEKERLRHLDMEHERLQLEKERLQIER 261 +++LE R+L E E Q+ ++ERL+ ++ERLR + ERL ++ERL + Sbjct: 170 RKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLRE---QEERLHEQEERLCEQE 226 Query: 262 EKLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEK 321 E+L Q E+ E E G++ +L+ E EKL LE+ER Q E++RL E E+ Sbjct: 227 ERLCEQ----EERLCEQEKLPGQERLLE----EVEKL-LEQERRQEEQERL----LERER 273 Query: 322 LQIEKERLQVEKDRLRIQKE 341 L E E L +E++RLR Q E Sbjct: 274 LLDEVEEL-LEQERLRQQDE 292 Score = 45.1 bits (105), Expect = 1e-04 Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 24/143 (16%) Query: 203 LLVNIEKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLDMEHERLQLEKERLQIERE 262 LL ++++L ++ RL + ERL ++ERL ++ERL E+E E+E Sbjct: 192 LLNRRQEERLREQEERLREQEERLHEQEERLCEQEERL-----------CEQEERLCEQE 240 Query: 263 KLRLQIVNSEKPSLENELGQGEKSMLQPQDIETEKLKLERERLQLEKDRLQFLKFESEKL 322 KL P E L + EK + Q + E ++ LERERL E + L E E+L Sbjct: 241 KL---------PGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEEL----LEQERL 287 Query: 323 QIEKERLQVEKDRLRIQKEGHLQ 345 + + ERL ++ +++ L+ Sbjct: 288 RQQDERLWQQETLRELERLRELE 310 Score = 42.0 bits (97), Expect = 8e-04 Identities = 44/152 (28%), Positives = 80/152 (52%), Gaps = 17/152 (11%) Query: 208 EKQKLELEKRRLDIEAERLQVEKERLQIEKERLRHLD--------MEHERLQLEKERLQI 259 ++++L ++ RL + ERL ++ERL ++ERL + +E LE+ER Q Sbjct: 204 QEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQE 263 Query: 260 EREKL--RLQIVNSEKPSLENE-LGQGEKSMLQPQDI-ETEKLKLERERLQLEKDRLQFL 315 E+E+L R ++++ + LE E L Q ++ + Q + + E E+L+ L+L + L Sbjct: 264 EQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLRELERMLELGWEALYEQ 323 Query: 316 KFES----EKLQIE-KERLQVEKDRLRIQKEG 342 + E E+L E K LQ+E+ ++K G Sbjct: 324 RAEPRSGFEELNNENKSTLQLEQQVKELEKSG 355 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.131 0.353 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,934,926 Number of Sequences: 37866 Number of extensions: 650332 Number of successful extensions: 11259 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 253 Number of HSP's successfully gapped in prelim test: 863 Number of HSP's that attempted gapping in prelim test: 4632 Number of HSP's gapped (non-prelim): 3918 length of query: 345 length of database: 18,247,518 effective HSP length: 103 effective length of query: 242 effective length of database: 14,347,320 effective search space: 3472051440 effective search space used: 3472051440 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.