Search of human proteins with 5870893

Search of human proteins with 5870893

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
         (504 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5870893 solute carrier family 38, member 3 [Homo sapiens]          997   0.0  
gi|193788624 solute carrier family 38, member 5 [Homo sapiens]        541   e-154
gi|219689132 solute carrier family 38, member 4 [Homo sapiens]        501   e-142
gi|18482385 solute carrier family 38, member 4 [Homo sapiens]         501   e-142
gi|21361602 solute carrier family 38, member 2 [Homo sapiens]         499   e-141
gi|117168277 amino acid transporter system A1 [Homo sapiens]          435   e-122
gi|117168275 amino acid transporter system A1 [Homo sapiens]          435   e-122
gi|24429574 solute carrier family 38, member 6 [Homo sapiens]         397   e-110
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ...   106   4e-23
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ...   106   4e-23
gi|122937281 solute carrier family 38, member 8 [Homo sapiens]        103   5e-22
gi|27735137 solute carrier family 38, member 11 [Homo sapiens]        101   1e-21
gi|8922692 solute carrier family 38, member 7 [Homo sapiens]           95   1e-19
gi|222418631 solute carrier family 36, member 2 [Homo sapiens]         58   2e-08
gi|40807351 solute carrier family 36 (proton/amino acid symporte...    57   4e-08
gi|222418629 solute carrier family 38, member 9 [Homo sapiens]         57   5e-08
gi|41352721 solute carrier family 36 member 1 [Homo sapiens]           47   4e-05
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ...    46   7e-05
gi|17999520 solute carrier family 32, member 1 [Homo sapiens]          46   7e-05
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ...    39   0.014
gi|46409360 G protein-coupled receptor 148 [Homo sapiens]              35   0.21 
gi|110347453 solute carrier family 7 (cationic amino acid transp...    33   0.79 
gi|4506403 G protein-coupled receptor, family C, group 5, member...    32   1.4  
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]            31   3.0  
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]             31   3.0  
gi|55741641 kinase D-interacting substrate of 220 kDa [Homo sapi...    31   3.0  
gi|118572606 hemicentin 1 [Homo sapiens]                               30   6.7  
gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]       30   6.7  
gi|32401435 G protein-coupled receptor 141 [Homo sapiens]              29   8.8  

>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
          Length = 504

 Score =  997 bits (2577), Expect = 0.0
 Identities = 504/504 (100%), Positives = 504/504 (100%)

Query: 1   MEAPLQTEMVELVPNGKHSEGLLPVITPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFT 60
           MEAPLQTEMVELVPNGKHSEGLLPVITPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFT
Sbjct: 1   MEAPLQTEMVELVPNGKHSEGLLPVITPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFT 60

Query: 61  DFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKS 120
           DFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKS
Sbjct: 61  DFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKS 120

Query: 121 SGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEE 180
           SGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEE
Sbjct: 121 SGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEE 180

Query: 181 KTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPC 240
           KTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPC
Sbjct: 181 KTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPC 240

Query: 241 PLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCH 300
           PLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCH
Sbjct: 241 PLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCH 300

Query: 301 PEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVD 360
           PEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVD
Sbjct: 301 PEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVD 360

Query: 361 PFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINL 420
           PFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINL
Sbjct: 361 PFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINL 420

Query: 421 LVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFL 480
           LVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFL
Sbjct: 421 LVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFL 480

Query: 481 LMTMSLSFIIIDWASGTSRHGGNH 504
           LMTMSLSFIIIDWASGTSRHGGNH
Sbjct: 481 LMTMSLSFIIIDWASGTSRHGGNH 504


>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
          Length = 472

 Score =  541 bits (1394), Expect = e-154
 Identities = 282/452 (62%), Positives = 341/452 (75%), Gaps = 17/452 (3%)

Query: 54  SKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYS 113
           SK   F DFEGKTSFGMSVFNLSNAIMGSGILGLAYAMA+TG+I FL LL  +ALLSSYS
Sbjct: 36  SKPVQFMDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYS 95

Query: 114 IHLLLKSSGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQ 173
           IHLLL  +G+ GIRAYEQLG RAFG  GK+  A  I L N+GAMSSYL+IIKSELPLVI 
Sbjct: 96  IHLLLTCAGIAGIRAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIG 155

Query: 174 TFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIY 233
           TFL ++ +  DW++ GN L+I+VSV IILPLALM+ LGYLGY+SG SL+CM+FFL++VIY
Sbjct: 156 TFLYMDPE-GDWFLKGNLLIIIVSVLIILPLALMKHLGYLGYTSGLSLTCMLFFLVSVIY 214

Query: 234 KKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPE--ASAFCTPSYFTLNSQTAYTIP 291
           KKF + C +            H E   E   L   P    ++ C    FT++SQ +YT+P
Sbjct: 215 KKFQLGCAI-----------GHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVP 263

Query: 292 IMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESE 351
           IMAFAFVCHPEVLPIYTEL  PSK++MQ ++N+SI  M+ MY L A FGYLTFY+ V++E
Sbjct: 264 IMAFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAE 323

Query: 352 LLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIA 411
           +LH YS+ DP   LILCVR+AVL AVTLTVP+VLFP+RRA+QQ+LFP + FSW RHV IA
Sbjct: 324 MLHMYSQKDP---LILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIA 380

Query: 412 VGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILA 471
           + LL  +N+LVI  P I  IFGVIG+TSAP LIFI P+IFY RI+P+E EP  S PKI A
Sbjct: 381 LILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSEVEPFLSWPKIQA 440

Query: 472 LCFAMLGFLLMTMSLSFIIIDWASGTSRHGGN 503
           LCF +LG L M +SL F+  +WA+G SR  G+
Sbjct: 441 LCFGVLGVLFMAVSLGFMFANWATGQSRMSGH 472


>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
          Length = 547

 Score =  501 bits (1289), Expect = e-142
 Identities = 265/467 (56%), Positives = 327/467 (70%), Gaps = 39/467 (8%)

Query: 64  GKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGV 123
           G TSFGMS FNLSNAIMGSGILGL+YAMANTGIILF+ +L AVA+LS YS+HLLLK++  
Sbjct: 73  GTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKE 132

Query: 124 VGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTS 183
            G   YE+LG +AFG PGK+ A ++IT+QNIGAMSSYL+IIK ELP VI+ F+ LEE T 
Sbjct: 133 GGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTG 192

Query: 184 DWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLP 243
           +WY+NGNYL+I VSV IILPL+L++ LGYLGY+SGFSL+CMVFF+  VIYKKF +PCPLP
Sbjct: 193 EWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLP 252

Query: 244 P--------NFNNT----------TGNFSHVEIVKEKVQ-------------------LQ 266
                    +FNNT              S V  + +                      ++
Sbjct: 253 VLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVE 312

Query: 267 VEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSI 326
            E  +   C P YF  NS+TAY IPI+ FAFVCHPEVLPIY+ELKD S++KMQ +SN+SI
Sbjct: 313 YEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISI 372

Query: 327 AVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLF 386
             M +MY LAALFGYLTFY  VE ELLH YSKV   D+ +L VR+AVL AVTLTVPIVLF
Sbjct: 373 TGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLF 432

Query: 387 PVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFI 446
           P+R ++  +LFP + FSW+RH LIA  L+   N+LVI  P I  IFG IGA+SA  LIFI
Sbjct: 433 PIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFI 492

Query: 447 FPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSLSFIIIDW 493
            PA+FY +++  +KE  RS  K+ AL F ++G   M  S++ IIIDW
Sbjct: 493 LPAVFYLKLV--KKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDW 537


>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
          Length = 547

 Score =  501 bits (1289), Expect = e-142
 Identities = 265/467 (56%), Positives = 327/467 (70%), Gaps = 39/467 (8%)

Query: 64  GKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGV 123
           G TSFGMS FNLSNAIMGSGILGL+YAMANTGIILF+ +L AVA+LS YS+HLLLK++  
Sbjct: 73  GTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKE 132

Query: 124 VGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTS 183
            G   YE+LG +AFG PGK+ A ++IT+QNIGAMSSYL+IIK ELP VI+ F+ LEE T 
Sbjct: 133 GGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTG 192

Query: 184 DWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLP 243
           +WY+NGNYL+I VSV IILPL+L++ LGYLGY+SGFSL+CMVFF+  VIYKKF +PCPLP
Sbjct: 193 EWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLP 252

Query: 244 P--------NFNNT----------TGNFSHVEIVKEKVQ-------------------LQ 266
                    +FNNT              S V  + +                      ++
Sbjct: 253 VLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVE 312

Query: 267 VEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSI 326
            E  +   C P YF  NS+TAY IPI+ FAFVCHPEVLPIY+ELKD S++KMQ +SN+SI
Sbjct: 313 YEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISI 372

Query: 327 AVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLF 386
             M +MY LAALFGYLTFY  VE ELLH YSKV   D+ +L VR+AVL AVTLTVPIVLF
Sbjct: 373 TGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLF 432

Query: 387 PVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFI 446
           P+R ++  +LFP + FSW+RH LIA  L+   N+LVI  P I  IFG IGA+SA  LIFI
Sbjct: 433 PIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFI 492

Query: 447 FPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSLSFIIIDW 493
            PA+FY +++  +KE  RS  K+ AL F ++G   M  S++ IIIDW
Sbjct: 493 LPAVFYLKLV--KKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDW 537


>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
          Length = 506

 Score =  499 bits (1286), Expect = e-141
 Identities = 263/464 (56%), Positives = 334/464 (71%), Gaps = 7/464 (1%)

Query: 44  EGKSFLQKSP-SKEPHFTDFE-GKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLF 101
           E ++FL +S   K+ + T+F  G TSFGMSVFNLSNAI+GSGILGL+YAMANTGI LF+ 
Sbjct: 47  ENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFII 106

Query: 102 LLTAVALLSSYSIHLLLKSSGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYL 161
           LLT V++ S YS+HLLLK++   G   YEQLGY+AFG  GKLAA+ +IT+QNIGAMSSYL
Sbjct: 107 LLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYL 166

Query: 162 YIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSL 221
           +I+K ELPLVIQ   N+E+KT  WY+NGNYLV+LVS+ +ILPL+L R LGYLGY+SG SL
Sbjct: 167 FIVKYELPLVIQALTNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSL 226

Query: 222 SCMVFFLIAVIYKKFHVPCPLPPN-FNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYF 280
            CMVFFLI VI KKF VPCP+      N T N +  +       L      +  C P YF
Sbjct: 227 LCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPALSHNVTENDSCRPHYF 286

Query: 281 TLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFG 340
             NSQT Y +PI+ F+FVCHP VLPIY ELKD S+++M ++S +S   M++MY LAALFG
Sbjct: 287 IFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRRRMMNVSKISFFAMFLMYLLAALFG 346

Query: 341 YLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQ 400
           YLTFY  VESELLHTYS +   D+L+L VR+AVL AVTLTVP+V+FP+R ++  +L  ++
Sbjct: 347 YLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVTLTVPVVIFPIRSSVTHLLCASK 406

Query: 401 EFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEK 460
           +FSW RH LI V +L   NLLVIF P I  IFG IGA++A  LIFI P+ FY +++  +K
Sbjct: 407 DFSWWRHSLITVSILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLV--KK 464

Query: 461 EPARSTPKILALCFAMLGFLLMTMSLSFIIIDWASGTSRHGGNH 504
           EP +S  KI AL F + G L+MT S++ I++DW       GG H
Sbjct: 465 EPMKSVQKIGALFFLLSGVLVMTGSMALIVLDWVHNAP--GGGH 506


>gi|117168277 amino acid transporter system A1 [Homo sapiens]
          Length = 487

 Score =  435 bits (1119), Expect = e-122
 Identities = 232/440 (52%), Positives = 300/440 (68%), Gaps = 21/440 (4%)

Query: 64  GKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGV 123
           G TS GMSVFNLSNAIMGSGILGLA+A+ANTGI+LFL LLT+V LLS YSI+LLL  S  
Sbjct: 69  GTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKE 128

Query: 124 VGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTS 183
            G   YE+LG + FGT GK     A +LQN GAM SYL+I+K+ELP  I+  +  EE  S
Sbjct: 129 TGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETFS 188

Query: 184 DWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLP 243
            WY++G  LV++V+  IILPL L++ LGYLGY+SGFSLSCMVFFLI VIYKKF +PC +P
Sbjct: 189 AWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVP 248

Query: 244 PNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEV 303
              +  + N ++ +                 CTP Y T NS+T Y +P +AFAFVCHP V
Sbjct: 249 ELNSTISANSTNADT----------------CTPKYVTFNSKTVYALPTIAFAFVCHPSV 292

Query: 304 LPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFD 363
           LPIY+ELKD S+KKMQ +SN+S   M++MYFL A+FGYLTFY+ V+S+LLH Y   D  D
Sbjct: 293 LPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKD--D 350

Query: 364 VLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVI 423
           +LIL VR+AV+ AV LTVP++ F VR ++ + L    +F+  RH ++   LL  INLLVI
Sbjct: 351 ILILTVRLAVIVAVILTVPVLFFTVRSSLFE-LAKKTKFNLCRHTVVTCILLVVINLLVI 409

Query: 424 FAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMT 483
           F P++  IFGV+G TSA  LIFI P+  Y +I  T+++  + T +I A  F  LG L   
Sbjct: 410 FIPSMKDIFGVVGVTSANMLIFILPSSLYLKI--TDQDGDKGTQRIWAALFLGLGVLFSL 467

Query: 484 MSLSFIIIDWASGTSRHGGN 503
           +S+  +I DWA  +S   G+
Sbjct: 468 VSIPLVIYDWACSSSSDEGH 487


>gi|117168275 amino acid transporter system A1 [Homo sapiens]
          Length = 487

 Score =  435 bits (1119), Expect = e-122
 Identities = 232/440 (52%), Positives = 300/440 (68%), Gaps = 21/440 (4%)

Query: 64  GKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGV 123
           G TS GMSVFNLSNAIMGSGILGLA+A+ANTGI+LFL LLT+V LLS YSI+LLL  S  
Sbjct: 69  GTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKE 128

Query: 124 VGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTS 183
            G   YE+LG + FGT GK     A +LQN GAM SYL+I+K+ELP  I+  +  EE  S
Sbjct: 129 TGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETFS 188

Query: 184 DWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLP 243
            WY++G  LV++V+  IILPL L++ LGYLGY+SGFSLSCMVFFLI VIYKKF +PC +P
Sbjct: 189 AWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVP 248

Query: 244 PNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEV 303
              +  + N ++ +                 CTP Y T NS+T Y +P +AFAFVCHP V
Sbjct: 249 ELNSTISANSTNADT----------------CTPKYVTFNSKTVYALPTIAFAFVCHPSV 292

Query: 304 LPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFD 363
           LPIY+ELKD S+KKMQ +SN+S   M++MYFL A+FGYLTFY+ V+S+LLH Y   D  D
Sbjct: 293 LPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKD--D 350

Query: 364 VLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVI 423
           +LIL VR+AV+ AV LTVP++ F VR ++ + L    +F+  RH ++   LL  INLLVI
Sbjct: 351 ILILTVRLAVIVAVILTVPVLFFTVRSSLFE-LAKKTKFNLCRHTVVTCILLVVINLLVI 409

Query: 424 FAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMT 483
           F P++  IFGV+G TSA  LIFI P+  Y +I  T+++  + T +I A  F  LG L   
Sbjct: 410 FIPSMKDIFGVVGVTSANMLIFILPSSLYLKI--TDQDGDKGTQRIWAALFLGLGVLFSL 467

Query: 484 MSLSFIIIDWASGTSRHGGN 503
           +S+  +I DWA  +S   G+
Sbjct: 468 VSIPLVIYDWACSSSSDEGH 487


>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
          Length = 456

 Score =  397 bits (1020), Expect = e-110
 Identities = 207/427 (48%), Positives = 282/427 (66%), Gaps = 19/427 (4%)

Query: 67  SFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGI 126
           SFG+SVFNL NAIMGSGILGLAY MANTG+  F FLL  VALL+SYS+HLLL       +
Sbjct: 46  SFGLSVFNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAV 105

Query: 127 RAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWY 186
            +YE LG  AFG PGKL  A  I +QNIGAMSSYL IIK+ELP  I  FL   + +  WY
Sbjct: 106 TSYEDLGLFAFGLPGKLVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLT-GDYSRYWY 164

Query: 187 MNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNF 246
           ++G  L+I++ V I+ PLAL+ ++G+LGY+S  S   M+FF + VI KK+ +PCPL  N+
Sbjct: 165 LDGQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNY 224

Query: 247 NNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPI 306
                  S+V               +  C P  F  + ++AY +P MAF+F+CH  +LPI
Sbjct: 225 VEKGFQISNV---------------TDDCKPKLFHFSKESAYALPTMAFSFLCHTSILPI 269

Query: 307 YTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLI 366
           Y EL+ PSKK+MQ+++N +IA+ +++YF++ALFGYLTFY+ VESELL  YSK    DV++
Sbjct: 270 YCELQSPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVV 329

Query: 367 LCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAP 426
           + V++ +L AV LTVP++ FP R+A+  M F N  FSW+RH LI + L   I LL I+ P
Sbjct: 330 MTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVP 389

Query: 427 NILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSL 486
           +I  +FGV+GA+++  LIFIFP +FY ++    +E   S  K+ A    + G L+   SL
Sbjct: 390 DIRNVFGVVGASTSTCLIFIFPGLFYLKL---SREDFLSWKKLGAFVLLIFGILVGNFSL 446

Query: 487 SFIIIDW 493
           + II DW
Sbjct: 447 ALIIFDW 453


>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
           sapiens]
          Length = 1119

 Score =  106 bits (265), Expect = 4e-23
 Identities = 96/399 (24%), Positives = 170/399 (42%), Gaps = 56/399 (14%)

Query: 72  VFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQ 131
           + N+ N+I+G  +L + +     GI+L   LL   + ++  S   L+KS+ +   R Y  
Sbjct: 12  ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAG 71

Query: 132 LGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNY 191
           L + A+G  GK+    ++    +G   ++ Y++  +L        N   +   + + G +
Sbjct: 72  LAFHAYGKAGKMLVETSMIGLMLGTCIAF-YVVIGDLGS------NFFARLFGFQVGGTF 124

Query: 192 ---LVILVSVTIILPLALMRQL--GYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNF 246
              L+  VS+ I+LPL+L R +      +S+   L   VF  + V+    H         
Sbjct: 125 RMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKH--------- 175

Query: 247 NNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPI 306
               G FS   + +      V  E    C              IPI   +F C  +VLP 
Sbjct: 176 ----GLFSGQWLRRVSY---VRWEGVFRC--------------IPIFGMSFACQSQVLPT 214

Query: 307 YTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLI 366
           Y  L +PS K M  I   S+ V+   Y +   FGY++F       +L  +    P +++ 
Sbjct: 215 YDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHF----PSNLVT 270

Query: 367 LCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQE----------FSWLRHVLIAVGLLT 416
             +RV  + +V +  P+++ P R+A+  +L   Q+             LR   + + ++ 
Sbjct: 271 EMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVF 330

Query: 417 CINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRI 455
              +  I  PN+  I G+ GAT    + FI PA+ Y +I
Sbjct: 331 GTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKI 369


>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
           sapiens]
          Length = 780

 Score =  106 bits (265), Expect = 4e-23
 Identities = 96/399 (24%), Positives = 170/399 (42%), Gaps = 56/399 (14%)

Query: 72  VFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQ 131
           + N+ N+I+G  +L + +     GI+L   LL   + ++  S   L+KS+ +   R Y  
Sbjct: 12  ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAG 71

Query: 132 LGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNY 191
           L + A+G  GK+    ++    +G   ++ Y++  +L        N   +   + + G +
Sbjct: 72  LAFHAYGKAGKMLVETSMIGLMLGTCIAF-YVVIGDLGS------NFFARLFGFQVGGTF 124

Query: 192 ---LVILVSVTIILPLALMRQL--GYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNF 246
              L+  VS+ I+LPL+L R +      +S+   L   VF  + V+    H         
Sbjct: 125 RMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKH--------- 175

Query: 247 NNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPI 306
               G FS   + +      V  E    C              IPI   +F C  +VLP 
Sbjct: 176 ----GLFSGQWLRRVSY---VRWEGVFRC--------------IPIFGMSFACQSQVLPT 214

Query: 307 YTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLI 366
           Y  L +PS K M  I   S+ V+   Y +   FGY++F       +L  +    P +++ 
Sbjct: 215 YDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHF----PSNLVT 270

Query: 367 LCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQE----------FSWLRHVLIAVGLLT 416
             +RV  + +V +  P+++ P R+A+  +L   Q+             LR   + + ++ 
Sbjct: 271 EMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVF 330

Query: 417 CINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRI 455
              +  I  PN+  I G+ GAT    + FI PA+ Y +I
Sbjct: 331 GTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKI 369


>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
          Length = 435

 Score =  103 bits (256), Expect = 5e-22
 Identities = 106/434 (24%), Positives = 188/434 (43%), Gaps = 53/434 (12%)

Query: 43  MEGKSFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFL 102
           MEG++   +   ++PH        S   +VF L  + +G+G+L   +A +  G ++  FL
Sbjct: 1   MEGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFL 60

Query: 103 LTAVALLSSYSIHLLLKSSGVVGIRAYEQLGYRAFGTP--GKLAAALAITLQNIGAMSSY 160
           +  V+L+   S  ++L  +  V  +A  Q   R    P  GKL  A  + L  +    ++
Sbjct: 61  VELVSLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFL-LNLLMISVAF 119

Query: 161 LYIIKSELPLVIQTFLN-LEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSS-- 217
           L +I  +L  +  + L+        WY +  + + L+SV +ILPL+  R++ +  Y+S  
Sbjct: 120 LRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSIL 179

Query: 218 GFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTP 277
           G   +C +  +I V Y  +      P              +V+E       P  S     
Sbjct: 180 GTLAACYLALVITVQYYLW------PQG------------LVRES-----HPSLSPASWT 216

Query: 278 SYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAA 337
           S F++        P + F F CH   + IY  ++  S      +S LS+    ++Y L  
Sbjct: 217 SVFSV-------FPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTG 269

Query: 338 LFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQM-- 395
           ++G+LTF   V +++L +Y      D++I+  RV    ++    PIVLF  R  +Q    
Sbjct: 270 VYGFLTFGTEVSADVLMSY---PGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWR 326

Query: 396 ----------LFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIF 445
                        +    W+R + + +  +T    + +F P++  I  +IG  S+ F IF
Sbjct: 327 RSCLGGWGPSALADPSGLWVR-MPLTILWVTVTLAMALFMPDLSEIVSIIGGISS-FFIF 384

Query: 446 IFPAIFYFRIMPTE 459
           IFP +     M  E
Sbjct: 385 IFPGLCLICAMGVE 398


>gi|27735137 solute carrier family 38, member 11 [Homo sapiens]
          Length = 384

 Score =  101 bits (252), Expect = 1e-21
 Identities = 95/403 (23%), Positives = 167/403 (41%), Gaps = 67/403 (16%)

Query: 91  MANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQLGYRAFGTPGKLAAALAIT 150
           M   G  L + LL  V+ ++ +S+ LL+K   + G   Y+ L  + FG PG L  ++   
Sbjct: 1   MKQAGFPLGILLLFWVSYVTDFSLVLLIKGGALSGTDTYQSLVNKTFGFPGYLLLSVLQF 60

Query: 151 LQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQL 210
           L        Y +I+  E                + ++  ++++ L +VT  LPL+L R +
Sbjct: 61  L--------YPFIVDPE----------------NVFIGRHFIIGLSTVTFTLPLSLYRNI 96

Query: 211 GYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPE 270
             LG  S  S       L  V+ +   +   +P                          +
Sbjct: 97  AKLGKVSLISTGLTTLILGIVMARAISLGPHIPKT-----------------------ED 133

Query: 271 ASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMY 330
           A  F  P+           + +M+FAF+CH     +Y+ L++P+  K   + ++SI +  
Sbjct: 134 AWVFAKPN-------AIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISV 186

Query: 331 IMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRR 390
            +    A  GYLTF    + +L   Y + D    L+   R      V LT P+  F  R 
Sbjct: 187 FICIFFATCGYLTFTGFTQGDLFENYCRNDD---LVTFGRFCYGVTVILTYPMECFVTRE 243

Query: 391 AIQQMLFPNQEFSWLRHVLIAVGLL---TCINLLVIFAPNILGIFGVIGATSAPFLIFIF 447
            I  + F     S + H+++ V ++   T ++LL+     +L + GV+ AT    LIFI 
Sbjct: 244 VIANVFF-GGNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATP---LIFII 299

Query: 448 PAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSLSFII 490
           P+  Y ++    +EP   + KI++     +G ++M       I
Sbjct: 300 PSACYLKL---SEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAI 339


>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
          Length = 462

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 93/431 (21%), Positives = 183/431 (42%), Gaps = 46/431 (10%)

Query: 64  GKTSFGMSVFNLSNAIMGSGILGLAYAMANTG-IILFLFLLTAVALLSSYSIHLLLKSSG 122
           G TS   ++F + NA +G+G+L    A +  G +   + L   + +     + +L   S 
Sbjct: 49  GTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQ 108

Query: 123 VVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKT 182
               R Y+++ +   G    +   +AI +   G   ++L II  +   +I       E  
Sbjct: 109 ASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGA 168

Query: 183 SD-WYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCP 241
           S  WY +  + + L +   ILPL++ R++G+  Y+S  S+    +++ A++  K+     
Sbjct: 169 SGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSV-VGTWYVTAIVIIKY----- 222

Query: 242 LPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHP 301
           + P+   T GN            +   P        S+  + +     +P + F F CH 
Sbjct: 223 IWPDKEMTPGN------------ILTRPA-------SWMAVFN----AMPTICFGFQCHV 259

Query: 302 EVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDP 361
             +P++  ++ P  K    +   ++ +   +Y    + G+LTF   V+ ++L +Y     
Sbjct: 260 SSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSE-- 317

Query: 362 FDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEF--------SWLRHVLIAVG 413
            D+ +   R  ++ +V  + PI+ F  R  ++ +    Q             R VL  + 
Sbjct: 318 -DMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLV 376

Query: 414 LLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALC 473
                 LL +F P+I  +  VIG  +A F IF+FP +   +   +E E  +     + + 
Sbjct: 377 WFLLTLLLALFIPDIGKVISVIGGLAACF-IFVFPGLCLIQAKLSEMEEVKPASWWVLVS 435

Query: 474 FAMLGFLLMTM 484
           +   G LL+T+
Sbjct: 436 Y---GVLLVTL 443


>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
          Length = 483

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 91/459 (19%), Positives = 182/459 (39%), Gaps = 82/459 (17%)

Query: 23  LPVITPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGS 82
           L +++P    +++E+      +  +FL +SPS+       +G T F  ++ +L    MG+
Sbjct: 18  LDLMSPPESAKKLEN------KDSTFLDESPSESAGLKKTKGITVF-QALIHLVKGNMGT 70

Query: 83  GILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLK-----------------SSGVVG 125
           GILGL  A+ N GI++    L  +  ++ + +H+L+K                  + + G
Sbjct: 71  GILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRLNKPFMDYGDTVMHG 130

Query: 126 IRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDW 185
           + A      +     G+   +  + +  +G    Y+  +   L  V++    +   T++ 
Sbjct: 131 LEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEA---VNSTTNNC 187

Query: 186 YMN---------GNYLVILVSVTIILPLALMRQLGYLG-YSSGFSLSCMVFFLIAVIYKK 235
           Y N          + L +L  +  ++ L L+R L  L  +S   ++S +V  +I + Y  
Sbjct: 188 YSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFSMLANISMLVSLVIIIQYIT 247

Query: 236 FHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAF 295
             +P P            S + +V           AS    P +F              F
Sbjct: 248 QEIPDP------------SRLPLV-----------ASWKTYPLFF----------GTAIF 274

Query: 296 AFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHT 355
           +F     VLP+  ++K  + +    I +L ++++  +Y   A  GYL F + +++ +   
Sbjct: 275 SFESIGVVLPLENKMK--NARHFPAILSLGMSIVTSLYIGMAALGYLRFGDDIKASI--- 329

Query: 356 YSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGL- 414
            S   P   L   V++  +  +  T  +  +     I           W   + +++ L 
Sbjct: 330 -SLNLPNCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFAISRVSTRWALPLDLSIRLV 388

Query: 415 ---LTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAI 450
              LTC  LL I  P +  +  ++G+ S   L  I P +
Sbjct: 389 MVCLTC--LLAILIPRLDLVISLVGSVSGTALALIIPPL 425


>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
           member 4 [Homo sapiens]
          Length = 504

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 91/466 (19%), Positives = 178/466 (38%), Gaps = 78/466 (16%)

Query: 53  PSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSY 112
           P ++ +  D +   SF  ++ +L    +G+G+LGL  A+ N GI+L    L  + ++S +
Sbjct: 46  PVQKHYQLDDQEGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVH 105

Query: 113 SIHLLLKSSGVVGIRAYEQ-LGY----------------RAFGTPGKLAAALAITLQNIG 155
            +H+L++ S  + +R  +  LGY                +     G+      + +  +G
Sbjct: 106 CMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLG 165

Query: 156 AMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGN---------YLVILVSVTIILPLAL 206
             S Y+  +   +  V + FL  +   S+   + N          + +L  +  I+ L  
Sbjct: 166 FCSVYIVFLAENVKQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVF 225

Query: 207 MRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQ 266
           +R+L  L +   F  +  +   + +IY+      P P N     G   +           
Sbjct: 226 IRELKNL-FVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKY----------- 273

Query: 267 VEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSI 326
                     P +F              FAF     VLP+  ++K+   K+     N+ +
Sbjct: 274 ----------PLFF----------GTAVFAFEGIGVVLPLENQMKE--SKRFPQALNIGM 311

Query: 327 AVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDV-LILCVRVAVLTAVTLTVPIVL 385
            ++  +Y   A  GY+ F++ ++  +        P DV L   V++     + +T  I  
Sbjct: 312 GIVTTLYVTLATLGYMCFHDEIKGSITLNL----PQDVWLYQSVKILYSFGIFVTYSIQF 367

Query: 386 FPVRRAIQQMLFPNQEFSW-------LRHVLIAVGLLTCINLLVIFAPNILGIFGVIGAT 438
           +     I   +       W       +R  L+++   TC   ++I  P +  +   +GA 
Sbjct: 368 YVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSI---TCAGAILI--PRLDIVISFVGAV 422

Query: 439 SAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCF-AMLGFLLMT 483
           S+  L  I P +        E        K +++ F  ++GFLL T
Sbjct: 423 SSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGT 468


>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
          Length = 561

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 95/457 (20%), Positives = 188/457 (41%), Gaps = 41/457 (8%)

Query: 52  SPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSS 111
           S  K   +T+  GK +  +++F + N +MG+ IL + + +   G    + ++  + LL+ 
Sbjct: 103 SAYKLQSYTEGYGKNTSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTL 162

Query: 112 YSIHLLLKSSGVVGIR-----AYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKS 166
           Y  + ++KS  ++         Y  +    FG+ G+ ++ L   +  IGAM  Y  ++ +
Sbjct: 163 YCCYRVVKSRTMMFSLDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSN 222

Query: 167 ELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLA-------------LMRQLGYL 213
            L    +   N     +D       L    S  +I P A                  G  
Sbjct: 223 FLFNTGKFIFNFIHHIND---TDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQ 279

Query: 214 GYSSGFSLSCMV-FFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVK----EKVQLQVE 268
            +   +  S  V F+L+ ++    +   P   +  N  G  S + ++     + V+L   
Sbjct: 280 QFEKWWDKSRTVPFYLVGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFLVTFKAVRLGFH 339

Query: 269 PEASAFCTPSYFT--LNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSI 326
            E   F    +F   +  Q      ++  AF  H  ++   T LK+ +KK+  ++ +L I
Sbjct: 340 LEFHWFIPTEFFVPEIRFQFPQLTGVLTLAFFIHNCII---TLLKN-NKKQENNVRDLCI 395

Query: 327 AVMYIM--YFLAALFGYLTFYNGVESELLHTYSKVDPF---DVLILCVRVAVLTAVTLTV 381
           A M +   Y    +  + +F +   S+     + +D F   D L    R+ +L  +    
Sbjct: 396 AYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFPSSDTLSFIARIFLLFQMMTVY 455

Query: 382 PIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVI-FAPNILGIFGVIGATSA 440
           P++ +  R  +   +F    +  + HVLI   ++    +++  F PNI GI    GA   
Sbjct: 456 PLLGYLARVQLLGHIF-GDIYPSIFHVLILNLIIVGAGVIMACFYPNIGGIIRYSGAACG 514

Query: 441 PFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAML 477
              +FI+P++ Y  I+   +E   + PK++   F ++
Sbjct: 515 LAFVFIYPSLIY--IISLHQEERLTWPKLIFHVFIII 549


>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
          Length = 476

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 101/478 (21%), Positives = 176/478 (36%), Gaps = 62/478 (12%)

Query: 38  PARSCMEGKSFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGII 97
           P  S  EG + L  SP     F      T F  ++ +L    +G+G+LGL  A+ N GI+
Sbjct: 21  PEESPSEGLNNLS-SPGSYQRFGQSNSTTWF-QTLIHLLKGNIGTGLLGLPLAVKNAGIV 78

Query: 98  LFLFLLTAVALLSSYSIHLLLKSSG-----------------VVGIRAYEQLGYRAFGTP 140
           +    L  + +++ + + +L+K +                  + G+ +      R     
Sbjct: 79  MGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHW 138

Query: 141 GKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTI 200
           G+      + +  +G    Y   +      VI+              NG       + T+
Sbjct: 139 GRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEA------------ANGTTNNCHNNETV 186

Query: 201 ILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVK 260
           IL   +  +L        + LS + F ++ V  +       +     N T   S V I +
Sbjct: 187 ILTPTMDSRL--------YMLSFLPFLVLLVFIRNLRA-LSIFSLLANITMLVSLVMIYQ 237

Query: 261 EKVQLQVEPEASAFCTP-SYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQ 319
             VQ   +P       P   + L   TA       F+F     VLP+  ++KDP  +K  
Sbjct: 238 FIVQRIPDPSHLPLVAPWKTYPLFFGTAI------FSFEGIGMVLPLENKMKDP--RKFP 289

Query: 320 HISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVL--TAV 377
            I  L + ++ I+Y      GYL F   ++  +         +  + L   + +    A+
Sbjct: 290 LILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYAL 349

Query: 378 TLTVP---IVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGV 434
              VP   I+ F V RA +        F  +R VL+    LTCI  L I  P +  +  +
Sbjct: 350 QFYVPAEIIIPFFVSRAPEHCELVVDLF--VRTVLVC---LTCI--LAILIPRLDLVISL 402

Query: 435 IGATSAPFLIFIFPAIFYFRIMPTE-KEPARSTPKILALCFAMLGFLLMTMSLSFIII 491
           +G+ S+  L  I P +       +E   P       L      +GF++ T    + +I
Sbjct: 403 VGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELI 460


>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
           sapiens]
          Length = 470

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 78/423 (18%), Positives = 163/423 (38%), Gaps = 65/423 (15%)

Query: 63  EGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLK--- 119
           E   S   ++ +L    +G+G+LGL  A+ N G+++    L A+ +L+ + + +LL    
Sbjct: 39  EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQ 98

Query: 120 --------------SSGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIK 165
                          + + G+        RA    G+   +  + +  +G  S Y   + 
Sbjct: 99  HLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMA 158

Query: 166 SELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMV 225
                      NL++     ++  N    +     IL L  +  + +      + L  + 
Sbjct: 159 D----------NLQQMVEKAHVTSN----ICQPREILTLTPILDIRF------YMLIILP 198

Query: 226 FFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSY--FTLN 283
           F ++ V  +   V        N TT     + ++ E +   +   ++     ++  F L 
Sbjct: 199 FLILLVFIQNLKVLSVFSTLANITT--LGSMALIFEYIMEGIPYPSNLPLMANWKTFLLF 256

Query: 284 SQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLT 343
             TA       F F     VLP+  ++K P  ++   +  L ++++ I+Y L    GY+ 
Sbjct: 257 FGTAI------FTFEGVGMVLPLKNQMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMK 308

Query: 344 FYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPI---VLFPVRRAIQQMLFPNQ 400
           F +  ++ +         +  + L   + +     L   +   ++ P   AI Q+     
Sbjct: 309 FGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPF--AISQV----- 361

Query: 401 EFSWLRHVLIAVG----LLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIM 456
             SW   V ++V      LTC++ ++I  P +  +  ++G+ S+  L  I PA+    I 
Sbjct: 362 SESWALFVDLSVRSALVCLTCVSAILI--PRLDLVISLVGSVSSSALALIIPALLEIVIF 419

Query: 457 PTE 459
            +E
Sbjct: 420 YSE 422


>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
          Length = 525

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 81/411 (19%), Positives = 171/411 (41%), Gaps = 79/411 (19%)

Query: 73  FNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLL-------KSSGVVG 125
           +N++NAI G  +LGL YA+ + G  L LFL+   A++  Y+  +L+       +   VV 
Sbjct: 123 WNVTNAIQGMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVR 181

Query: 126 IR-AYEQLGYRA----FGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEE 180
           +R +Y  +        F T G     +A  ++ +  M+  LY++ S   L+  +F  L  
Sbjct: 182 VRDSYVAIANACCAPRFPTLGGRVVNVAQIIELV--MTCILYVVVSG-NLMYNSFPGLPV 238

Query: 181 KTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSC-MVFFLIAVIYKKFHVP 239
               W         +++  ++LP A ++ L  +   S FSL C +  F+I ++   + + 
Sbjct: 239 SQKSW--------SIIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYCLS 287

Query: 240 CPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVC 299
                            +   EKV+  ++ +              +   +I I+ F++  
Sbjct: 288 --------------RARDWAWEKVKFYIDVK--------------KFPISIGIIVFSYTS 319

Query: 300 HPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKV 359
              +  +   ++ PS  +   + N +     ++  L AL  YLT+ +  +  +       
Sbjct: 320 QIFLPSLEGNMQQPS--EFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNL--- 374

Query: 360 DPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFP--NQEF------------SWL 405
            P  +  + V + ++    L+ P+  F     +++ LF   ++ F            SW 
Sbjct: 375 -PGSIRAV-VNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSW- 431

Query: 406 RHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIM 456
             + +   L+    L+ I+ P+   + G+ G+ +   L F+ P++F+ R++
Sbjct: 432 -GLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLL 481


>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
           sapiens]
          Length = 511

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 35/164 (21%), Positives = 73/164 (44%), Gaps = 18/164 (10%)

Query: 303 VLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPF 362
           VLP+  ++K P  ++   +  L ++++ I+Y L    GY+ F +  ++ +         +
Sbjct: 311 VLPLKNQMKHP--QQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLPNCWLY 368

Query: 363 DVLILCVRVAVLTAVTLTVPI---VLFPVRRAIQQMLFPNQEFSWLRHVLIAVG----LL 415
             + L   + +     L   +   ++ P   AI Q+       SW   V ++V      L
Sbjct: 369 QSVKLMYSIGIFFTYALQFHVPAEIIIPF--AISQV-----SESWALFVDLSVRSALVCL 421

Query: 416 TCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTE 459
           TC++ ++I  P +  +  ++G+ S+  L  I PA+    I  +E
Sbjct: 422 TCVSAILI--PRLDLVISLVGSVSSSALALIIPALLEIVIFYSE 463



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 16/56 (28%), Positives = 32/56 (57%)

Query: 63  EGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLL 118
           E   S   ++ +L    +G+G+LGL  A+ N G+++    L A+ +L+ + + +LL
Sbjct: 39  EAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILL 94


>gi|46409360 G protein-coupled receptor 148 [Homo sapiens]
          Length = 347

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 40/136 (29%), Positives = 63/136 (46%), Gaps = 19/136 (13%)

Query: 86  GLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQLGY-RAFGTPGKLA 144
           GL   +  T I+  LFL TA+     + I+   K+SG+ G       GY RA GT   L 
Sbjct: 214 GLLVIVTYTSILCVLFLCTALIANCFWRIYAEAKTSGIWG------QGYSRARGT--LLI 265

Query: 145 AALAITLQ-NIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILP 203
            ++ ITL  + G + S        L +V+  + +++  T  W +  N  V+++    +LP
Sbjct: 266 HSVLITLYVSTGVVFS--------LDMVLTRYHHIDSGTHTWLLAANSEVLMMLPRAMLP 317

Query: 204 -LALMRQLGYLGYSSG 218
            L L+R    LG   G
Sbjct: 318 YLYLLRYRQLLGMVRG 333


>gi|110347453 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 4 [Homo sapiens]
          Length = 635

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 27/114 (23%), Positives = 49/114 (42%), Gaps = 28/114 (24%)

Query: 403 SWLRHVLIAVGLLTCINLLVI----------------FAPNILGIFGVIGATSAPFLIFI 446
           SWL H   A+ LL  + ++++                FAP   G  GV+  T++ F  F+
Sbjct: 192 SWLNHTFSAISLLVILFIVILGFILAQPHNWSADEGGFAP--FGFSGVMAGTASCFYAFV 249

Query: 447 FPAIFYFRIMPTEKE----PARSTPKILALCFAM-LGFLLMTMSLSFIIIDWAS 495
                 F ++    E    P RS P  +A+  A+  G  ++  ++  +++ W S
Sbjct: 250 -----GFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHS 298


>gi|4506403 G protein-coupled receptor, family C, group 5, member A
           [Homo sapiens]
          Length = 357

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 23/157 (14%)

Query: 346 NGVESELLHTYSKVDPFDVLILCVRVA-VLTAVT--LTVPIVLFPVRRAIQQMLFPNQEF 402
           NG++S+      K + + +++  V  A V+T+V   LT+PI++  V+ + ++ + P Q  
Sbjct: 11  NGLKSKYYRLCDKAEAWGIVLETVATAGVVTSVAFMLTLPILVCKVQDSNRRKMLPTQ-- 68

Query: 403 SWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIF------IFPAIFYFRIM 456
                 L  +G+L    L   F   I+G+ G  G T   F +F       F  +    + 
Sbjct: 69  -----FLFLLGVLGIFGLTFAF---IIGLDGSTGPTR--FFLFGILFSICFSCLLAHAVS 118

Query: 457 PTEKEPARSTPKILALCFAMLGFLLM--TMSLSFIII 491
            T+    R    +L +    +GF L+   +++ +I++
Sbjct: 119 LTKLVRGRKPLSLLVILGLAVGFSLVQDVIAIEYIVL 155


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 19/78 (24%), Positives = 34/78 (43%)

Query: 427 NILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSL 486
           NI     V+  T++   +F+     Y  +M   + P   TP  +A+   ++  + +T+S 
Sbjct: 92  NIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSF 151

Query: 487 SFIIIDWASGTSRHGGNH 504
             I + W S      GNH
Sbjct: 152 LSIHLGWNSRNETSKGNH 169


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 19/78 (24%), Positives = 34/78 (43%)

Query: 427 NILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSL 486
           NI     V+  T++   +F+     Y  +M   + P   TP  +A+   ++  + +T+S 
Sbjct: 92  NIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSF 151

Query: 487 SFIIIDWASGTSRHGGNH 504
             I + W S      GNH
Sbjct: 152 LSIHLGWNSRNETSKGNH 169


>gi|55741641 kinase D-interacting substrate of 220 kDa [Homo
           sapiens]
          Length = 1771

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 3/60 (5%)

Query: 394 QMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYF 453
           Q + P  +FSWL   ++ + LL C  L ++FA  +    G+  + S   L++IF  + YF
Sbjct: 489 QQIEPLFQFSWL---IVFLTLLLCGGLGLLFAFTVHPNLGIAVSLSFLALLYIFFIVIYF 545


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 28/120 (23%), Positives = 52/120 (43%), Gaps = 7/120 (5%)

Query: 165  KSE-LPLVIQTFLNLEEKTSDW------YMNGNYLVILVSVTIILPLALMRQLGYLGYSS 217
            KSE L +V+  F++L  + S +      ++     + L + T+I+P     Q+     S 
Sbjct: 2970 KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSD 3029

Query: 218  GFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTP 277
            G   +C+         KKF +   +PP+  +       V  V+E   + +E E++A   P
Sbjct: 3030 GGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPP 3089


>gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]
          Length = 981

 Score = 29.6 bits (65), Expect = 6.7
 Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 2/89 (2%)

Query: 68  FGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIR 127
           +G+ V  L  A++    L  A A     ++  + +L A AL S+Y +     S   +G+R
Sbjct: 476 YGVGVLFLLPALLALAALAAAPAGPRLALVAAVLVLVASALRSAYMLTDPYGSQARLGVR 535

Query: 128 AYEQLGYRAFGTPGKLAAALAITLQNIGA 156
               L    F  P  L A  A+TL  +GA
Sbjct: 536 GGLVLYNLPF--PLLLTALAALTLLGLGA 562


>gi|32401435 G protein-coupled receptor 141 [Homo sapiens]
          Length = 305

 Score = 29.3 bits (64), Expect = 8.8
 Identities = 20/98 (20%), Positives = 48/98 (48%), Gaps = 6/98 (6%)

Query: 325 SIAVMYIMYFLAALFGYLTFYNG-----VESELLHTYSKVDPFDVLILCVRVAVLTAVTL 379
           ++ ++ ++  + + +G    YN         EL +TY K+  + ++I  + VAV+  V  
Sbjct: 141 TLVIVIVVPLVVSRYGIHEEYNEEHCFKFHKELAYTYVKIINYMIVIFVIAVAVILLV-F 199

Query: 380 TVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTC 417
            V I++  V++    +L   + ++ L+++     +L C
Sbjct: 200 QVFIIMLMVQKLRHSLLSHQEFWAQLKNLFFIGVILVC 237


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,979,453
Number of Sequences: 37866
Number of extensions: 767979
Number of successful extensions: 2370
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2298
Number of HSP's gapped (non-prelim): 51
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.