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Search of human proteins with 5730091
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens]
(235 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens] 507 e-144
gi|5454114 tissue factor pathway inhibitor isoform a precursor [... 138 5e-33
gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2 ... 100 1e-21
gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2 p... 100 1e-21
gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1 ... 96 3e-20
gi|73760409 tissue factor pathway inhibitor isoform b precursor ... 91 9e-19
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 72 4e-13
gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo sap... 72 5e-13
gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo sapi... 70 2e-12
gi|28212222 WFIKKN2 protein [Homo sapiens] 70 2e-12
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 66 2e-11
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 66 2e-11
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 66 2e-11
gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo sap... 62 4e-10
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 60 1e-09
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP... 60 2e-09
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP... 60 2e-09
gi|41406055 amyloid beta A4 protein isoform b precursor [Homo sa... 59 4e-09
gi|4502167 amyloid beta A4 protein isoform a precursor [Homo sap... 59 4e-09
gi|209915573 amyloid beta A4 protein isoform f precursor [Homo s... 59 4e-09
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa... 57 1e-08
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa... 57 1e-08
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 54 9e-08
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 54 9e-08
gi|145309328 papilin [Homo sapiens] 54 2e-07
gi|110626171 serine peptidase inhibitor, Kunitz type 4 [Homo sap... 51 8e-07
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 51 8e-07
gi|29725609 epidermal growth factor receptor isoform a precursor... 35 0.073
gi|41327736 epidermal growth factor receptor isoform d precursor... 35 0.073
gi|41327734 epidermal growth factor receptor isoform c precursor... 35 0.073
>gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens]
Length = 235
Score = 507 bits (1306), Expect = e-144
Identities = 235/235 (100%), Positives = 235/235 (100%)
Query: 1 MDPARPLGLSILLLFLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQS 60
MDPARPLGLSILLLFLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQS
Sbjct: 1 MDPARPLGLSILLLFLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQS 60
Query: 61 CRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSM 120
CRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSM
Sbjct: 61 CRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSM 120
Query: 121 TCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRY 180
TCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRY
Sbjct: 121 TCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRY 180
Query: 181 RTCDAFTYTGCGGNDNNFVSREDCKRACAKALKKKKKMPKLRFASRIRKIRKKQF 235
RTCDAFTYTGCGGNDNNFVSREDCKRACAKALKKKKKMPKLRFASRIRKIRKKQF
Sbjct: 181 RTCDAFTYTGCGGNDNNFVSREDCKRACAKALKKKKKMPKLRFASRIRKIRKKQF 235
>gi|5454114 tissue factor pathway inhibitor isoform a precursor
[Homo sapiens]
Length = 304
Score = 138 bits (347), Expect = 5e-33
Identities = 78/241 (32%), Positives = 109/241 (45%), Gaps = 57/241 (23%)
Query: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRI------ 89
C D GPC+A++ R++++ +T+ C +F+YGGCEGN N F + E C C R
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 90 -----EKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEAT 144
++ P C L+ C G +YF+N + CE+F GGC N N F
Sbjct: 114 KTTLQQEKPDFCFLEED-PGICRGYITRYFYNNQTKQCERFKYGGCLGNM--NNFETLEE 170
Query: 145 CMGFC-----------------------APKKI----------PSFCYSPKDEGLCSANV 171
C C P+ PS+C +P D GLC AN
Sbjct: 171 CKNICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANE 230
Query: 172 TRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKA----------LKKKKKMPKL 221
R+Y+N C F Y+GCGGN+NNF S+++C RAC K +K K+K K
Sbjct: 231 NRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQ 290
Query: 222 R 222
R
Sbjct: 291 R 291
Score = 60.5 bits (145), Expect = 1e-09
Identities = 26/59 (44%), Positives = 35/59 (59%)
Query: 152 KKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
K + SFC D+G C A + R++FN R C+ F Y GC GN N F S E+CK+ C +
Sbjct: 48 KLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR 106
>gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 100 bits (248), Expect = 1e-21
Identities = 67/195 (34%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 29 TGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWR 88
T + CL G CR R+YYD Q C+ F+YGGC GN NN+ E C AC
Sbjct: 243 TKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRG 302
Query: 89 IEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATC--- 145
++ R V C G+ + F S+ C F C DEA C
Sbjct: 303 VQGPSMERRHPV-----CSGTCQPTQFRCSNGCCIDSFLE-CDDTPNCPDASDEAACEKY 356
Query: 146 -MGFCAPKKI--PS---FCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFV 199
GF ++I PS C D GLC ++ R+Y+NP C FTY GC GN NNF
Sbjct: 357 TSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFE 416
Query: 200 SREDCKRACAKALKK 214
+ C +C KK
Sbjct: 417 EEQQCLESCRGISKK 431
>gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 100 bits (248), Expect = 1e-21
Identities = 67/195 (34%), Positives = 85/195 (43%), Gaps = 15/195 (7%)
Query: 29 TGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWR 88
T + CL G CR R+YYD Q C+ F+YGGC GN NN+ E C AC
Sbjct: 243 TKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRG 302
Query: 89 IEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATC--- 145
++ R V C G+ + F S+ C F C DEA C
Sbjct: 303 VQGPSMERRHPV-----CSGTCQPTQFRCSNGCCIDSFLE-CDDTPNCPDASDEAACEKY 356
Query: 146 -MGFCAPKKI--PS---FCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFV 199
GF ++I PS C D GLC ++ R+Y+NP C FTY GC GN NNF
Sbjct: 357 TSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFE 416
Query: 200 SREDCKRACAKALKK 214
+ C +C KK
Sbjct: 417 EEQQCLESCRGISKK 431
>gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1
precursor [Homo sapiens]
Length = 529
Score = 95.9 bits (237), Expect = 3e-20
Identities = 69/210 (32%), Positives = 88/210 (41%), Gaps = 29/210 (13%)
Query: 29 TGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWR 88
T + CL G CR R+YYD Q C+ F+YGGC GN NN+ E C AC
Sbjct: 243 TKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRG 302
Query: 89 IEKVPKVCRLQVSVDDQ---------------CEGSTEKYFFNLSSMTCEKFFSGGCHRN 133
++ P L+ S Q C G+ + F S+ C F C
Sbjct: 303 VQGGP----LRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFL-ECDDT 357
Query: 134 RIENRFPDEATC----MGFCAPKKI--PS---FCYSPKDEGLCSANVTRYYFNPRYRTCD 184
DEA C GF ++I PS C D GLC ++ R+Y+NP C
Sbjct: 358 PNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCA 417
Query: 185 AFTYTGCGGNDNNFVSREDCKRACAKALKK 214
FTY GC GN NNF + C +C KK
Sbjct: 418 RFTYGGCYGNKNNFEEEQQCLESCRGISKK 447
>gi|73760409 tissue factor pathway inhibitor isoform b precursor
[Homo sapiens]
Length = 251
Score = 90.9 bits (224), Expect = 9e-19
Identities = 41/118 (34%), Positives = 62/118 (52%), Gaps = 14/118 (11%)
Query: 103 DDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCA------------ 150
D C+ +++FFN+ + CE+F GGC N +NRF C C
Sbjct: 60 DGPCKAIMKRFFFNIFTRQCEEFIYGGCEGN--QNRFESLEECKKMCTRDNANRIIKTTL 117
Query: 151 PKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
++ P FC+ +D G+C +TRY++N + + C+ F Y GC GN NNF + E+CK C
Sbjct: 118 QQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
Score = 84.0 bits (206), Expect = 1e-16
Identities = 42/125 (33%), Positives = 61/125 (48%), Gaps = 14/125 (11%)
Query: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWR------- 88
C D GPC+A++ R++++ +T+ C +F+YGGCEGN N F + E C C R
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 89 ----IEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEAT 144
++ P C L+ C G +YF+N + CE+F GGC N N F
Sbjct: 114 KTTLQQEKPDFCFLEED-PGICRGYITRYFYNNQTKQCERFKYGGCLGNM--NNFETLEE 170
Query: 145 CMGFC 149
C C
Sbjct: 171 CKNIC 175
Score = 62.0 bits (149), Expect = 4e-10
Identities = 25/53 (47%), Positives = 32/53 (60%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
+ C L D G CR + RY+Y+ T+ C +F YGGC GN NNF T E C + C
Sbjct: 123 DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
Score = 60.5 bits (145), Expect = 1e-09
Identities = 26/59 (44%), Positives = 35/59 (59%)
Query: 152 KKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
K + SFC D+G C A + R++FN R C+ F Y GC GN N F S E+CK+ C +
Sbjct: 48 KLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTR 106
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 72.0 bits (175), Expect = 4e-13
Identities = 41/121 (33%), Positives = 61/121 (50%), Gaps = 3/121 (2%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVP 93
+ C+LP GPCR R+ Y Q C F+YGGCEGN NNF++ E+C+DAC + + P
Sbjct: 357 DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC-PVPRTP 415
Query: 94 --KVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAP 151
+ CRL+ + S L+ + E +GG R +E+ D+ + F
Sbjct: 416 PCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIARVALEDVLKDDKMGLKFLGT 475
Query: 152 K 152
K
Sbjct: 476 K 476
Score = 56.2 bits (134), Expect = 2e-08
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 5/113 (4%)
Query: 43 GPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSV 102
GP L+ ++YD C F GC+G A F T+EAC AC R P + +V
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR---GPGDACVLPAV 364
Query: 103 DDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
C G ++ ++ C F GGC N N F +C C + P
Sbjct: 365 QGPCRGWEPRWAYSPLLQQCHPFVYGGCEGN--GNNFHSRESCEDACPVPRTP 415
Score = 52.4 bits (124), Expect = 3e-07
Identities = 30/87 (34%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 122 CEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYR 181
C F + GC + F C CA + C P +G C R+ ++P +
Sbjct: 326 CMTFPARGC--DGAARGFETYEACQQACA-RGPGDACVLPAVQGPCRGWEPRWAYSPLLQ 382
Query: 182 TCDAFTYTGCGGNDNNFVSREDCKRAC 208
C F Y GC GN NNF SRE C+ AC
Sbjct: 383 QCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 33.5 bits (75), Expect = 0.16
Identities = 14/46 (30%), Positives = 25/46 (54%)
Query: 165 GLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
G S ++ ++++P+ C F GC G F + E C++ACA+
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR 353
>gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo
sapiens]
Length = 352
Score = 71.6 bits (174), Expect = 5e-13
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 89 IEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGF 148
+ K C+L S C G T +YF+N +SM CE F GGC N N F E C+
Sbjct: 224 VTKKEDSCQLGYSAGP-CMGMTSRYFYNGTSMACETFQYGGCMGNG--NNFVTEKECLQT 280
Query: 149 CAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
C + + C P G C A + + F+ C F Y GC GN N F S ++C+ C
Sbjct: 281 C---RTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 70.1 bits (170), Expect = 2e-12
Identities = 38/114 (33%), Positives = 51/114 (44%), Gaps = 7/114 (6%)
Query: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKV 95
C L GPC + RY+Y+ + +C F YGGC GN NNF T + C C +
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTC----RTVAA 286
Query: 96 CRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
C L + V C + + F+ C F GGC N N+F E C +C
Sbjct: 287 CNLPI-VRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN--GNKFYSEKECREYC 337
>gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo
sapiens]
Length = 252
Score = 70.1 bits (170), Expect = 2e-12
Identities = 43/150 (28%), Positives = 63/150 (42%), Gaps = 36/150 (24%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRI---- 89
+ CL+ G CRA + R++Y+ SC+ F+YGGC+GN+NN+ T E C C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 90 ------------EKVPKVCRLQVSVDDQ------------------CEGSTEKYFFNLSS 119
VP R Q S D C S +++F++
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 120 MTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
+C F GGC N+ N + E CM C
Sbjct: 156 NSCNNFIYGGCRGNK--NSYRSEEACMLRC 183
Score = 60.1 bits (144), Expect = 2e-09
Identities = 27/63 (42%), Positives = 36/63 (57%)
Query: 31 NNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIE 90
N E C GPCRA R+Y+D SC F+YGGC GN N++ + EAC C+R +
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQ 187
Query: 91 KVP 93
+ P
Sbjct: 188 ENP 190
Score = 57.0 bits (136), Expect = 1e-08
Identities = 37/159 (23%), Positives = 65/159 (40%), Gaps = 42/159 (26%)
Query: 105 QCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAP------------- 151
+C S ++++N++ +C+ F GGC N N + + C+ CA
Sbjct: 46 RCRASMPRWWYNVTDGSCQLFVYGGCDGN--SNNYLTKEECLKKCATVTENATGDLATSR 103
Query: 152 ----KKIPS-------------------FCYSPKDEGLCSANVTRYYFNPRYRTCDAFTY 188
+PS +C + G C A+ R+YF+ +C+ F Y
Sbjct: 104 NAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIY 163
Query: 189 TGCGGNDNNFVSREDCKRACAKALKKKKKMPKLRFASRI 227
GC GN N++ S E C C ++++ P L S++
Sbjct: 164 GGCRGNKNSYRSEEACMLRCF----RQQENPPLPLGSKV 198
Score = 56.6 bits (135), Expect = 2e-08
Identities = 22/58 (37%), Positives = 35/58 (60%)
Query: 152 KKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACA 209
+ I FC K G C A++ R+++N +C F Y GC GN NN++++E+C + CA
Sbjct: 32 RSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCA 89
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 70.1 bits (170), Expect = 2e-12
Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 3/105 (2%)
Query: 104 DQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKD 163
+ C ++ F+ + C F G CHRN N F CM C + + C P
Sbjct: 335 EDCGEEQTRWHFDAQANNCLTFTFGHCHRNL--NHFETYEACMLACMSGPLAA-CSLPAL 391
Query: 164 EGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
+G C A R+ +N + C +F Y GC GN NNF SRE C+ +C
Sbjct: 392 QGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
Score = 65.1 bits (157), Expect = 5e-11
Identities = 26/51 (50%), Positives = 35/51 (68%)
Query: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
C LP GPC+A R+ Y+ T C+ F+YGGCEGN NNF + EAC+++C
Sbjct: 386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
Score = 63.9 bits (154), Expect = 1e-10
Identities = 45/154 (29%), Positives = 68/154 (44%), Gaps = 15/154 (9%)
Query: 19 AALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYT 78
AA +++ T A CL P D C R+++D +C F +G C N N+F T
Sbjct: 311 AATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFET 370
Query: 79 WEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGC--HRNRIE 136
+EAC AC + C L ++ C+ ++ +N + C+ F GGC + N E
Sbjct: 371 YEACMLAC--MSGPLAACSLP-ALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFE 427
Query: 137 NRFPDEATC--------MGFCAP--KKIPSFCYS 160
+R E +C C P K + SFC S
Sbjct: 428 SREACEESCPFPRGNQRCRACKPRQKLVTSFCRS 461
Score = 41.2 bits (95), Expect = 8e-04
Identities = 20/65 (30%), Positives = 29/65 (44%)
Query: 158 CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKKKKK 217
C P D C TR++F+ + C FT+ C N N+F + E C AC
Sbjct: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAACS 387
Query: 218 MPKLR 222
+P L+
Sbjct: 388 LPALQ 392
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 66.2 bits (160), Expect = 2e-11
Identities = 25/57 (43%), Positives = 38/57 (66%)
Query: 158 CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
C PKDEG C + ++Y++P ++C F Y GCGGN+N F S+++C++ CA L K
Sbjct: 2906 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 2962
Score = 65.1 bits (157), Expect = 5e-11
Identities = 28/62 (45%), Positives = 38/62 (61%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVP 93
+IC LP D G CR +L++YYD T+SC +F YGGC GN N F + + C+ C + P
Sbjct: 2904 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKP 2963
Query: 94 KV 95
V
Sbjct: 2964 GV 2965
Score = 37.0 bits (84), Expect = 0.015
Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Query: 95 VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAP 151
+C+L + C K++++ ++ +C +F+ GGC N EN+F + C CAP
Sbjct: 2905 ICKLPKD-EGTCRDFILKWYYDPNTKSCARFWYGGCGGN--ENKFGSQKECEKVCAP 2958
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 66.2 bits (160), Expect = 2e-11
Identities = 25/57 (43%), Positives = 38/57 (66%)
Query: 158 CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
C PKDEG C + ++Y++P ++C F Y GCGGN+N F S+++C++ CA L K
Sbjct: 3112 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 3168
Score = 65.1 bits (157), Expect = 5e-11
Identities = 28/62 (45%), Positives = 38/62 (61%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVP 93
+IC LP D G CR +L++YYD T+SC +F YGGC GN N F + + C+ C + P
Sbjct: 3110 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKP 3169
Query: 94 KV 95
V
Sbjct: 3170 GV 3171
Score = 37.0 bits (84), Expect = 0.015
Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Query: 95 VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAP 151
+C+L + C K++++ ++ +C +F+ GGC N EN+F + C CAP
Sbjct: 3111 ICKLPKD-EGTCRDFILKWYYDPNTKSCARFWYGGCGGN--ENKFGSQKECEKVCAP 3164
>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
sapiens]
Length = 2570
Score = 66.2 bits (160), Expect = 2e-11
Identities = 25/57 (43%), Positives = 38/57 (66%)
Query: 158 CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
C PKDEG C + ++Y++P ++C F Y GCGGN+N F S+++C++ CA L K
Sbjct: 2505 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 2561
Score = 65.1 bits (157), Expect = 5e-11
Identities = 28/62 (45%), Positives = 38/62 (61%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVP 93
+IC LP D G CR +L++YYD T+SC +F YGGC GN N F + + C+ C + P
Sbjct: 2503 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKP 2562
Query: 94 KV 95
V
Sbjct: 2563 GV 2564
Score = 37.0 bits (84), Expect = 0.015
Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Query: 95 VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAP 151
+C+L + C K++++ ++ +C +F+ GGC N EN+F + C CAP
Sbjct: 2504 ICKLPKD-EGTCRDFILKWYYDPNTKSCARFWYGGCGGN--ENKFGSQKECEKVCAP 2557
>gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo
sapiens]
Length = 89
Score = 62.0 bits (149), Expect = 4e-10
Identities = 23/55 (41%), Positives = 35/55 (63%)
Query: 154 IPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
+P+ C P ++G C +TR++FN C+ F Y GCGGN NNF+ +E C++ C
Sbjct: 32 LPNVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 86
Score = 58.5 bits (140), Expect = 5e-09
Identities = 21/52 (40%), Positives = 32/52 (61%)
Query: 35 ICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
+C P++ GPC+ + R++++ T C F YGGC GN+NNF E C+ C
Sbjct: 35 VCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 86
Score = 35.0 bits (79), Expect = 0.056
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 92 VPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
+P VC + C+ ++FFN + CE F GGC N N F + C FC
Sbjct: 32 LPNVCAFPME-KGPCQTYMTRWFFNFETGECELFAYGGCGGN--SNNFLRKEKCEKFC 86
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 60.5 bits (145), Expect = 1e-09
Identities = 28/54 (51%), Positives = 34/54 (62%), Gaps = 3/54 (5%)
Query: 36 CLLPLDYGPCRALLLRYYYDRYT---QSCRQFLYGGCEGNANNFYTWEACDDAC 86
C LPLD G C A LR+Y+ T ++C F+YGGC GNAN F T EAC+ C
Sbjct: 2876 CSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929
Score = 51.2 bits (121), Expect = 8e-07
Identities = 24/54 (44%), Positives = 28/54 (51%), Gaps = 3/54 (5%)
Query: 158 CYSPKDEGLCSANVTRYYFNP---RYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
C P DEG C+A R+Y C F Y GCGGN N F +RE C+R C
Sbjct: 2876 CSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929
>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 2 [Homo sapiens]
Length = 117
Score = 60.1 bits (144), Expect = 2e-09
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
++C +P + GPC A L ++YD+ +C F+YGGC+GN NNF + C + C
Sbjct: 59 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 111
Score = 54.7 bits (130), Expect = 7e-08
Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 141 DEATCMGFCAPKKI----PSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDN 196
D C F KK C PK+ G C A ++++ + TC F Y GC GN+N
Sbjct: 40 DNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNN 99
Query: 197 NFVSREDCKRACAKALKKKKKMP 219
NF S+ +C C K K+ P
Sbjct: 100 NFQSKANCLNTC-----KNKRFP 117
Score = 33.9 bits (76), Expect = 0.12
Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 113 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
++++ TC F GGC N N F +A C+ C K+ P
Sbjct: 77 WWYDKKDNTCSMFVYGGCQGNN--NNFQSKANCLNTCKNKRFP 117
>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 1 precursor [Homo sapiens]
Length = 133
Score = 60.1 bits (144), Expect = 2e-09
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
++C +P + GPC A L ++YD+ +C F+YGGC+GN NNF + C + C
Sbjct: 75 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 54.7 bits (130), Expect = 7e-08
Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 141 DEATCMGFCAPKKI----PSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDN 196
D C F KK C PK+ G C A ++++ + TC F Y GC GN+N
Sbjct: 56 DNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNN 115
Query: 197 NFVSREDCKRACAKALKKKKKMP 219
NF S+ +C C K K+ P
Sbjct: 116 NFQSKANCLNTC-----KNKRFP 133
Score = 33.9 bits (76), Expect = 0.12
Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 113 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
++++ TC F GGC N N F +A C+ C K+ P
Sbjct: 93 WWYDKKDNTCSMFVYGGCQGNN--NNFQSKANCLNTCKNKRFP 133
>gi|41406055 amyloid beta A4 protein isoform b precursor [Homo
sapiens]
Length = 751
Score = 58.9 bits (141), Expect = 4e-09
Identities = 25/53 (47%), Positives = 31/53 (58%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
E+C + GPCRA++ R+Y+D C F YGGC GN NNF T E C C
Sbjct: 289 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 51.6 bits (122), Expect = 6e-07
Identities = 22/55 (40%), Positives = 29/55 (52%)
Query: 158 CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKAL 212
C + G C A ++R+YF+ C F Y GCGGN NNF + E C C A+
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAI 345
Score = 40.8 bits (94), Expect = 0.001
Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 90 EKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
E V +VC Q C +++F+++ C FF GGC NR N F E CM C
Sbjct: 285 EVVREVCSEQAETGP-CRAMISRWYFDVTEGKCAPFFYGGCGGNR--NNFDTEEYCMAVC 341
Query: 150 APKKIPSFCYSPKD 163
IP+ S D
Sbjct: 342 G-SAIPTTAASTPD 354
>gi|4502167 amyloid beta A4 protein isoform a precursor [Homo
sapiens]
Length = 770
Score = 58.9 bits (141), Expect = 4e-09
Identities = 25/53 (47%), Positives = 31/53 (58%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
E+C + GPCRA++ R+Y+D C F YGGC GN NNF T E C C
Sbjct: 289 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 52.0 bits (123), Expect = 4e-07
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 158 CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
C + G C A ++R+YF+ C F Y GCGGN NNF + E C C A+ +
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQ 347
Score = 39.7 bits (91), Expect = 0.002
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 90 EKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
E V +VC Q C +++F+++ C FF GGC NR N F E CM C
Sbjct: 285 EVVREVCSEQAETGP-CRAMISRWYFDVTEGKCAPFFYGGCGGNR--NNFDTEEYCMAVC 341
>gi|209915573 amyloid beta A4 protein isoform f precursor [Homo
sapiens]
Length = 714
Score = 58.9 bits (141), Expect = 4e-09
Identities = 25/53 (47%), Positives = 31/53 (58%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
E+C + GPCRA++ R+Y+D C F YGGC GN NNF T E C C
Sbjct: 233 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 285
Score = 52.0 bits (123), Expect = 4e-07
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 158 CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
C + G C A ++R+YF+ C F Y GCGGN NNF + E C C A+ +
Sbjct: 235 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQ 291
Score = 39.7 bits (91), Expect = 0.002
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 90 EKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
E V +VC Q C +++F+++ C FF GGC NR N F E CM C
Sbjct: 229 EVVREVCSEQAETGP-CRAMISRWYFDVTEGKCAPFFYGGCGGNR--NNFDTEEYCMAVC 285
>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 57.0 bits (136), Expect = 1e-08
Identities = 26/58 (44%), Positives = 33/58 (56%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEK 91
E C+LP+ +G C R+++D C F Y GCEGNANNF +AC AC I K
Sbjct: 93 EPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150
Score = 50.1 bits (118), Expect = 2e-06
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 145 CMGFCAPKKIPSF---CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSR 201
C C K + F C P G C+ R++F+ + C F Y GC GN NNF++
Sbjct: 79 CFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNE 138
Query: 202 EDCKRACAKALK 213
+ C+ AC +K
Sbjct: 139 DACRTACMLIVK 150
>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 57.0 bits (136), Expect = 1e-08
Identities = 26/58 (44%), Positives = 33/58 (56%)
Query: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEK 91
E C+LP+ +G C R+++D C F Y GCEGNANNF +AC AC I K
Sbjct: 93 EPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150
Score = 50.1 bits (118), Expect = 2e-06
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 145 CMGFCAPKKIPSF---CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSR 201
C C K + F C P G C+ R++F+ + C F Y GC GN NNF++
Sbjct: 79 CFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNE 138
Query: 202 EDCKRACAKALK 213
+ C+ AC +K
Sbjct: 139 DACRTACMLIVK 150
>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
[Homo sapiens]
Length = 751
Score = 54.3 bits (129), Expect = 9e-08
Identities = 24/61 (39%), Positives = 35/61 (57%)
Query: 26 QEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDA 85
+E T + +C GPCRA++ R+Y+D C +F+YGGC GN NNF + + C
Sbjct: 300 KEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAV 359
Query: 86 C 86
C
Sbjct: 360 C 360
Score = 46.6 bits (109), Expect = 2e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 154 IPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALK 213
+ + C G C A + R+YF+ C F Y GCGGN NNF S + C C KA+
Sbjct: 306 VKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC-KAMI 364
Query: 214 KKKKMP 219
+P
Sbjct: 365 PPTPLP 370
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 92 VPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
V VC Q ++ C +++F+LS C +F GGC NR N F E CM C
Sbjct: 306 VKAVCS-QEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNR--NNFESEDYCMAVC 360
>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
[Homo sapiens]
Length = 763
Score = 54.3 bits (129), Expect = 9e-08
Identities = 24/61 (39%), Positives = 35/61 (57%)
Query: 26 QEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDA 85
+E T + +C GPCRA++ R+Y+D C +F+YGGC GN NNF + + C
Sbjct: 300 KEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAV 359
Query: 86 C 86
C
Sbjct: 360 C 360
Score = 46.6 bits (109), Expect = 2e-05
Identities = 24/66 (36%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 154 IPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALK 213
+ + C G C A + R+YF+ C F Y GCGGN NNF S + C C KA+
Sbjct: 306 VKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC-KAMI 364
Query: 214 KKKKMP 219
+P
Sbjct: 365 PPTPLP 370
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 92 VPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
V VC Q ++ C +++F+LS C +F GGC NR N F E CM C
Sbjct: 306 VKAVCS-QEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNR--NNFESEDYCMAVC 360
>gi|145309328 papilin [Homo sapiens]
Length = 1251
Score = 53.5 bits (127), Expect = 2e-07
Identities = 22/51 (43%), Positives = 29/51 (56%)
Query: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
CLLP +G C R+Y+ C +F YGGC GNANNF + + C +C
Sbjct: 727 CLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 777
Score = 50.4 bits (119), Expect = 1e-06
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 128 GGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFT 187
G C+ N P C+G + P C P G C+ R+YF C+ F
Sbjct: 698 GCCYDNVATAAGPLGEGCVGQPS-HAYPVRCLLPSAHGSCADWAARWYFVASVGQCNRFW 756
Query: 188 YTGCGGNDNNFVSREDCKRACAKAL 212
Y GC GN NNF S ++C +C +L
Sbjct: 757 YGGCHGNANNFASEQECMSSCQGSL 781
Score = 36.2 bits (82), Expect = 0.025
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 101 SVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
S C +++F S C +F+ GGCH N N F E CM C
Sbjct: 731 SAHGSCADWAARWYFVASVGQCNRFWYGGCHGN--ANNFASEQECMSSC 777
>gi|110626171 serine peptidase inhibitor, Kunitz type 4 [Homo
sapiens]
Length = 99
Score = 51.2 bits (121), Expect = 8e-07
Identities = 23/70 (32%), Positives = 39/70 (55%)
Query: 25 AQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDD 84
A++ G+ + C L +++G C + RY+Y+R ++ C F++ GC GN NNF +
Sbjct: 30 AEKICGDLKDPCKLDMNFGSCYEVHFRYFYNRTSKRCETFVFSGCNGNLNNFKLKIEREV 89
Query: 85 ACWRIEKVPK 94
AC K P+
Sbjct: 90 ACVAKYKPPR 99
Score = 40.8 bits (94), Expect = 0.001
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 149 CAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
C K P C + G C RY++N + C+ F ++GC GN NNF + + + AC
Sbjct: 34 CGDLKDP--CKLDMNFGSCYEVHFRYFYNRTSKRCETFVFSGCNGNLNNFKLKIEREVAC 91
Query: 209 AKALK 213
K
Sbjct: 92 VAKYK 96
Score = 28.9 bits (63), Expect = 4.0
Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 3/60 (5%)
Query: 96 CRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGC--HRNRIENRFPDEATCMGFCAPKK 153
C+L ++ C +YF+N +S CE F GC + N + + E C+ P +
Sbjct: 41 CKLDMNFGS-CYEVHFRYFYNRTSKRCETFVFSGCNGNLNNFKLKIEREVACVAKYKPPR 99
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 51.2 bits (121), Expect = 8e-07
Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
Query: 23 DAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEAC 82
D A++P CL L G C ++R+YYD+ SC +F + GC G+ N F + + C
Sbjct: 1065 DGAEDPR------CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKEC 1118
Query: 83 DDAC 86
+ C
Sbjct: 1119 QETC 1122
Score = 44.7 bits (104), Expect = 7e-05
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 158 CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
C G C V R+Y++ + +C F ++GC G+ N F S ++C+ C
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122
>gi|29725609 epidermal growth factor receptor isoform a precursor
[Homo sapiens]
Length = 1210
Score = 34.7 bits (78), Expect = 0.073
Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 26/166 (15%)
Query: 54 YDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKY 113
+ + SC++ C+ + N W A ++ C ++ K+ +C Q S +C G +
Sbjct: 180 FQNHLGSCQK-----CDPSCPNGSCWGAGEENCQKLTKI--ICAQQCS--GRCRGKSP-- 228
Query: 114 FFNLSSMTCEKFFSGGCHRNR-----IENRFPDEATCMGFCAPKKI---PSFCYSPKDEG 165
S C + GC R + +F DEATC C P + ++ EG
Sbjct: 229 -----SDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEG 283
Query: 166 LCSANVTRYYFNPR-YRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
S T PR Y D + G D ++ ED R C K
Sbjct: 284 KYSFGATCVKKCPRNYVVTDHGSCVRACGAD-SYEMEEDGVRKCKK 328
>gi|41327736 epidermal growth factor receptor isoform d precursor
[Homo sapiens]
Length = 705
Score = 34.7 bits (78), Expect = 0.073
Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 26/166 (15%)
Query: 54 YDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKY 113
+ + SC++ C+ + N W A ++ C ++ K+ +C Q S +C G +
Sbjct: 180 FQNHLGSCQK-----CDPSCPNGSCWGAGEENCQKLTKI--ICAQQCS--GRCRGKSP-- 228
Query: 114 FFNLSSMTCEKFFSGGCHRNR-----IENRFPDEATCMGFCAPKKI---PSFCYSPKDEG 165
S C + GC R + +F DEATC C P + ++ EG
Sbjct: 229 -----SDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEG 283
Query: 166 LCSANVTRYYFNPR-YRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
S T PR Y D + G D ++ ED R C K
Sbjct: 284 KYSFGATCVKKCPRNYVVTDHGSCVRACGAD-SYEMEEDGVRKCKK 328
>gi|41327734 epidermal growth factor receptor isoform c precursor
[Homo sapiens]
Length = 405
Score = 34.7 bits (78), Expect = 0.073
Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 26/166 (15%)
Query: 54 YDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKY 113
+ + SC++ C+ + N W A ++ C ++ K+ +C Q S +C G +
Sbjct: 180 FQNHLGSCQK-----CDPSCPNGSCWGAGEENCQKLTKI--ICAQQCS--GRCRGKSP-- 228
Query: 114 FFNLSSMTCEKFFSGGCHRNR-----IENRFPDEATCMGFCAPKKI---PSFCYSPKDEG 165
S C + GC R + +F DEATC C P + ++ EG
Sbjct: 229 -----SDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEG 283
Query: 166 LCSANVTRYYFNPR-YRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
S T PR Y D + G D ++ ED R C K
Sbjct: 284 KYSFGATCVKKCPRNYVVTDHGSCVRACGAD-SYEMEEDGVRKCKK 328
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.460
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,110,312
Number of Sequences: 37866
Number of extensions: 480798
Number of successful extensions: 1181
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1059
Number of HSP's gapped (non-prelim): 95
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.