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Search of human proteins with 5730037
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5730037 SEC10 protein [Homo sapiens]
(708 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5730037 SEC10 protein [Homo sapiens] 1411 0.0
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 52 1e-06
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 45 2e-04
gi|169215514 PREDICTED: hypothetical protein [Homo sapiens] 41 0.003
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 41 0.004
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 41 0.004
gi|169215927 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006
gi|239752137 PREDICTED: hypothetical protein [Homo sapiens] 40 0.006
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 40 0.006
gi|24430190 keratin 15 [Homo sapiens] 40 0.007
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 40 0.007
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 39 0.022
gi|4504063 golgin 97 [Homo sapiens] 39 0.022
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 39 0.022
gi|169215483 PREDICTED: hypothetical protein isoform 2 [Homo sap... 38 0.028
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 38 0.037
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 38 0.037
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 37 0.048
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 37 0.063
gi|170932494 syntaxin 7 [Homo sapiens] 37 0.082
gi|4758650 kinesin family member 5C [Homo sapiens] 37 0.082
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 37 0.082
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 37 0.082
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 37 0.082
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 36 0.11
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 36 0.11
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 36 0.11
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 36 0.11
gi|157427195 hypothetical protein LOC347475 [Homo sapiens] 36 0.11
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 36 0.11
>gi|5730037 SEC10 protein [Homo sapiens]
Length = 708
Score = 1411 bits (3652), Expect = 0.0
Identities = 708/708 (100%), Positives = 708/708 (100%)
Query: 1 MATTAELFEEPFVADEYIERLVWRTPGGGSRGGPEAFDPKRLLEEFVNHIQELQIMDERI 60
MATTAELFEEPFVADEYIERLVWRTPGGGSRGGPEAFDPKRLLEEFVNHIQELQIMDERI
Sbjct: 1 MATTAELFEEPFVADEYIERLVWRTPGGGSRGGPEAFDPKRLLEEFVNHIQELQIMDERI 60
Query: 61 QRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGV 120
QRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGV
Sbjct: 61 QRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGV 120
Query: 121 NTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSE 180
NTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSE
Sbjct: 121 NTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSE 180
Query: 181 VKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGA 240
VKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGA
Sbjct: 181 VKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGA 240
Query: 241 YLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQNVFEIKLQSFVKEQLEECRKSDA 300
YLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQNVFEIKLQSFVKEQLEECRKSDA
Sbjct: 241 YLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQNVFEIKLQSFVKEQLEECRKSDA 300
Query: 301 EQYLKNLYDLYTRTTNLSSKLMEFNLGTDKQTFLSKLIKSIFISYLENYIEVETGYLKSR 360
EQYLKNLYDLYTRTTNLSSKLMEFNLGTDKQTFLSKLIKSIFISYLENYIEVETGYLKSR
Sbjct: 301 EQYLKNLYDLYTRTTNLSSKLMEFNLGTDKQTFLSKLIKSIFISYLENYIEVETGYLKSR 360
Query: 361 SAMILQRYYDSKNHQKRSIGTGGIQDLKERIRQRTNLPLGPSIDTHGETFLSQEVVVNLL 420
SAMILQRYYDSKNHQKRSIGTGGIQDLKERIRQRTNLPLGPSIDTHGETFLSQEVVVNLL
Sbjct: 361 SAMILQRYYDSKNHQKRSIGTGGIQDLKERIRQRTNLPLGPSIDTHGETFLSQEVVVNLL 420
Query: 421 QETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEHIDYALETGLAGIPSSDSRNANL 480
QETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEHIDYALETGLAGIPSSDSRNANL
Sbjct: 421 QETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEHIDYALETGLAGIPSSDSRNANL 480
Query: 481 YFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLSECLQKKKEIIEQMEMKLDTGIDRTL 540
YFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLSECLQKKKEIIEQMEMKLDTGIDRTL
Sbjct: 481 YFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLSECLQKKKEIIEQMEMKLDTGIDRTL 540
Query: 541 NCMIGQMKHILAAEQKKTDFKPEDENNVLIQYTNACVKVCAYVRKQVEKIKNSMDGKNVD 600
NCMIGQMKHILAAEQKKTDFKPEDENNVLIQYTNACVKVCAYVRKQVEKIKNSMDGKNVD
Sbjct: 541 NCMIGQMKHILAAEQKKTDFKPEDENNVLIQYTNACVKVCAYVRKQVEKIKNSMDGKNVD 600
Query: 601 TVLMELGVRFHRLIYEHLQQYSYSCMGGMLAICDVAEYRKCAKDFKIPMVLHLFDTLHAL 660
TVLMELGVRFHRLIYEHLQQYSYSCMGGMLAICDVAEYRKCAKDFKIPMVLHLFDTLHAL
Sbjct: 601 TVLMELGVRFHRLIYEHLQQYSYSCMGGMLAICDVAEYRKCAKDFKIPMVLHLFDTLHAL 660
Query: 661 CNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYRSARLARHFS 708
CNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYRSARLARHFS
Sbjct: 661 CNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYRSARLARHFS 708
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 52.4 bits (124), Expect = 1e-06
Identities = 79/347 (22%), Positives = 160/347 (46%), Gaps = 40/347 (11%)
Query: 51 QELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQ-HFQELD----EHISY 105
++LQ++ ++ Q ++EKL ++C++E + L K ++ FQ H +E++ E +
Sbjct: 629 EKLQVLKQQYQTEMEKLREKCEQEK-------ETLLKDKEIIFQAHIEEMNEKTLEKLDV 681
Query: 106 VATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADIIQK 165
T++ L +L V R + E ++K + + EL++ + ++ D I K
Sbjct: 682 KQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIK 741
Query: 166 LHLIA----QELPFDRFSEVKSKIASK-YHDLECQLIQEFTSAQRRGEISRMREVAAVLL 220
H ++ ++ D+ ++++ + + H E Q E A + +++ +A L
Sbjct: 742 EHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 801
Query: 221 HFKGYSHCVDVYIKQCQEG-AYLRNDI--FEDAGILCQRVNKQVGDIFSNPETVLAKLIQ 277
F+ Y K +E A L+ + E IL + KQV ++ + + V +L
Sbjct: 802 VFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERIL---LTKQVAEVEAQKKDVCTEL-- 856
Query: 278 NVFEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRTTNLSSKLMEFNLGTDKQTFLSKL 337
+ +I++Q + +QLE+ + S+ EQ +K+L +Y +K E KQ + K
Sbjct: 857 DAHKIQVQDLM-QQLEK-QNSEMEQKVKSLTQVYESKLEDGNKEQE----QTKQILVEK- 909
Query: 338 IKSIFISYLENY---IEVETGYL--KSRSAMILQRYYDS--KNHQKR 377
+++ + E IE+ T L K S IL Y++ KN +K+
Sbjct: 910 -ENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 955
Score = 41.2 bits (95), Expect = 0.003
Identities = 63/289 (21%), Positives = 120/289 (41%), Gaps = 36/289 (12%)
Query: 40 KRLLEEFVNHIQELQIMDERIQRKVEKLE----QQCQKEAKEFAKKVQELQKSNQVAFQH 95
+R L + EL + +QR+ +KL+ Q K + A+ +ELQ Q A +H
Sbjct: 147 ERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQ-AKKH 205
Query: 96 FQ--------ELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKS 147
Q E D++IS + T+V L +L N P V+ K + E ++
Sbjct: 206 LQEEFDASLEEKDQYISVLQTQVSLLKQRLR--NGPMN--VDVLKPLPQL------EPQA 255
Query: 148 DVFT-------NSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEF 200
+VFT + E + E ++ L + Q + + K + H +C L+
Sbjct: 256 EVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSE 315
Query: 201 TSAQRRGEISRMREVAAVL-LHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNK 259
A + R++E+ + LH + I Q ++ L + +D G++ +
Sbjct: 316 KEALQEQLDERLQELEKIKDLHMAEKTK----LITQLRDAKNLIEQLEQDKGMVIAETKR 371
Query: 260 QVGDIFSNPETVLAKLIQNVFEIKLQ-SFVKEQLEECRKSDAEQYLKNL 307
Q+ + E +A+L + ++ Q ++EQ E+ ++ E+ K L
Sbjct: 372 QMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKAL 420
Score = 35.8 bits (81), Expect = 0.14
Identities = 42/168 (25%), Positives = 77/168 (45%), Gaps = 38/168 (22%)
Query: 48 NHIQELQIM-----------DERIQRKVEKLEQQ-----CQKEAKEFAKKVQELQKSN-- 89
N ++ELQI DE+I E+L+QQ C K E K E ++SN
Sbjct: 1458 NTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLE 1517
Query: 90 ---QVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLD-GEL 145
+ EL++HI+ ++ L + L+ N +Q+ +E ++L++ F + GE
Sbjct: 1518 TELKSQTARIMELEDHITQKTIEIESLNEVLKNYN--QQKDIEHKELVQKLQHFQELGEE 1575
Query: 146 KSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLE 193
K + ++KEA + I L ++ +K+++ +K +LE
Sbjct: 1576 KDN------RVKEAEEKILTLE--------NQVYSMKAELETKKKELE 1609
Score = 35.4 bits (80), Expect = 0.18
Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 6/162 (3%)
Query: 45 EFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHIS 104
E +HI + I E + ++ QQ E KE +K+Q Q+ + +E +E I
Sbjct: 1529 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKIL 1588
Query: 105 YVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADIIQ 164
+ +V + +LE + + K + + L+ L+S+ ++K A+ Q
Sbjct: 1589 TLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE--Q 1646
Query: 165 KLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRR 206
K+ I ++L S+++ K E L + T Q R
Sbjct: 1647 KIAAIKKQL----LSQMEEKEEQYKKGTESHLSELNTKLQER 1684
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 45.4 bits (106), Expect = 2e-04
Identities = 67/291 (23%), Positives = 122/291 (41%), Gaps = 28/291 (9%)
Query: 40 KRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQEL 99
K L+ E NH++E Q E + + E + +Q Q+E + KK + S +V ++ L
Sbjct: 1194 KELISE-CNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINL 1252
Query: 100 DEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLD---GELKSDVFTNSEKI 156
++ + K+ + +QL+ AV + M+ + L+ +LK V +KI
Sbjct: 1253 EDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKI 1312
Query: 157 KEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVA 216
+E +QK +L+ L D ++K K+ LEC L QE + + RE+
Sbjct: 1313 EE----LQK-NLLNANLSEDEKEQLK-KLMELKQSLECNLDQEM-----KKNVELEREIT 1361
Query: 217 AVLLHFKGYSHCVDVYIKQCQEGAY-----LRNDIFEDAGILCQRVNKQVGDIFSNPETV 271
FK + + + G + L+ FE I ++ ++ D+ + ET
Sbjct: 1362 G----FKNLLKMTRKKLNEYENGEFSFHGDLKTSQFE-MDIQINKLKHKIDDLTAELETA 1416
Query: 272 LAKLIQNVFEIKLQSFVKEQLE-ECRKSDAEQYLKNLYDLYTRTTNLSSKL 321
+K + + K Q +E L + + E+ KN L NL S +
Sbjct: 1417 GSKCLH--LDTKNQILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHI 1465
Score = 36.2 bits (82), Expect = 0.11
Identities = 97/434 (22%), Positives = 174/434 (40%), Gaps = 63/434 (14%)
Query: 35 EAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAK----------KVQE 84
E D K+ L + N +QE Q R EK++ QK K+ AK K++E
Sbjct: 1255 ETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEE 1314
Query: 85 LQK---SNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLM-----KY 136
LQK + ++ ++L + + + C+L DQ N +R + K + K
Sbjct: 1315 LQKNLLNANLSEDEKEQLKKLMELKQSLECNL-DQEMKKNVELEREITGFKNLLKMTRKK 1373
Query: 137 FNEFLDGELKSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYH-DLECQ 195
NE+ +GE + + + I + H I D +E+++ + H D + Q
Sbjct: 1374 LNEYENGEFSFHGDLKTSQFEMDIQINKLKHKID-----DLTAELETAGSKCLHLDTKNQ 1428
Query: 196 LIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQ 255
++QE E+ M+ V + ++ QE LR+ I + L Q
Sbjct: 1429 ILQE--------ELLSMKTVQKKCEKLQKNKKKLE------QEVINLRSHIERNMVELGQ 1474
Query: 256 RVNKQVGDIFSNPETVLAKLIQNV-FEIKLQSFVKEQLEECRKSD----AEQYLKNLYDL 310
V + +I +A+ ++ V ++ Q+ +E LE+ R+++ Q + DL
Sbjct: 1475 -VKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDL 1533
Query: 311 YTRTTNLSSKLMEFN---LGTDKQTFLSKL-----IKSIFISYLENYIEVETGYL--KSR 360
+ + + + +FN L KQ +L +L + S E EV T L K +
Sbjct: 1534 ESELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQ 1593
Query: 361 SAMILQRYYDSKNHQKRSIGT-GGIQDLKERIRQRTNLPLGPS----IDTHGETFLS--- 412
S + + +G DL ++ R NL + S + E +LS
Sbjct: 1594 SRSLFTTLTTRPVMEPPCVGNLNNSLDLNRKLIPRENLVISTSNPRASNNSMENYLSKMQ 1653
Query: 413 QEVVVNLLQETKQA 426
QE+ N+ +E K+A
Sbjct: 1654 QELEKNITRELKEA 1667
>gi|169215514 PREDICTED: hypothetical protein [Homo sapiens]
Length = 357
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/180 (22%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 44 EEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFA--------KKVQELQKSNQVAFQH 95
E +Q+L + + R+ + Q Q EA+E A ++++E ++ + QH
Sbjct: 84 ESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQH 143
Query: 96 FQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEK 155
++L E +++++ + G +L+ + Q+ A +L+ NE E K + EK
Sbjct: 144 SRQLQEQWEELSSQLFYYGGELQSQKSTEQQL--AAQLVTLQNELELAETKCAL--QEEK 199
Query: 156 IK-------EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLEC-QLIQEFTSAQRRG 207
++ EA I Q+ ++ Q P EV+ K+ +L+ Q +E Q RG
Sbjct: 200 LQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRG 259
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 40.8 bits (94), Expect = 0.004
Identities = 100/502 (19%), Positives = 192/502 (38%), Gaps = 61/502 (12%)
Query: 42 LLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDE 101
L E I+ L+ +E + + V L Q+ Q A+ +V++++K N++ + +E
Sbjct: 545 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA---RVKDIEKENKILHESIKETSS 601
Query: 102 HISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAAD 161
+S + + + +LE +RA E + + + + + EL TN +K +
Sbjct: 602 KLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEK--ENELLQKKITN---LKITCE 656
Query: 162 IIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQL--IQEFTSAQRRGEISRMREVAAVL 219
I+ L EL +R + K + +L QL +++ S + R V ++
Sbjct: 657 KIEALEQENSEL--ERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESL- 713
Query: 220 LHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQNV 279
C + + Q Q L N E ++ + + F E + ++
Sbjct: 714 -------KCASMKMAQLQ----LENKELESEKEQLKKGLELLKASFKKTERL--EVSYQG 760
Query: 280 FEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRTTNLSSKLMEFNLGTDKQTFLSKLIK 339
+I+ Q +++ LE K +Q L DL L L E + + + L K K
Sbjct: 761 LDIENQR-LQKTLENSNKK-IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK 818
Query: 340 SIFISYLENYIEVETGYLKSRSAMILQRYYDSKNHQKRSIGTGGIQDLKERIRQRTNLPL 399
S +E ET L+ D K +K + ++K+ + N+ +
Sbjct: 819 S---------LEQETSQLEK----------DKKQLEKENKRLRQQAEIKDTTLEENNVKI 859
Query: 400 GPSIDTHGETFLSQEVVVNLLQETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEHI 459
G +++ +T LS+E+ + E C RL + + + TI ++ L
Sbjct: 860 G-NLEKENKT-LSKEIGIYK--------ESCVRLKELEKENKELVKRATIDIKTLVTLRE 909
Query: 460 DYALETGLAGIPSSDSRNANLYFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLSECLQ 519
D E ++D + + H D+Q D L+ S KL L+
Sbjct: 910 DLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLH--DEQSTDDRYKLLES--KLESTLK 965
Query: 520 KKKEIIEQMEMKLDTGIDRTLN 541
K EI E+ L+ ++ + N
Sbjct: 966 KSLEIKEEKIAALEARLEESTN 987
>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
sapiens]
Length = 1719
Score = 40.8 bits (94), Expect = 0.004
Identities = 37/171 (21%), Positives = 76/171 (44%), Gaps = 23/171 (13%)
Query: 33 GPEAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQ---CQKEAKEFAKKVQELQ--- 86
GP + D L+ V + + E +R++++LEQ+ ++ +E + VQ LQ
Sbjct: 421 GPTSLD----LDVNVQRTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYST 476
Query: 87 ------KSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEF 140
S + ++ +E E + T+ HL QLE N RQ +A + +K + +
Sbjct: 477 VDGPLTASKDLEIKNLKEEIEKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQ 536
Query: 141 LD------GELKSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKI 185
+ +L ++ SE++K + ++ H ++L F E+ ++
Sbjct: 537 IKTLQQEREDLNKELVQASERLKNQSKELKDAH-CQRKLAMQEFMEINERL 586
>gi|169215927 PREDICTED: hypothetical protein [Homo sapiens]
Length = 357
Score = 40.4 bits (93), Expect = 0.006
Identities = 41/180 (22%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 44 EEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFA--------KKVQELQKSNQVAFQH 95
E +Q+L + + R+ + Q Q EA+E A ++++E ++ + QH
Sbjct: 84 ESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEDLEQH 143
Query: 96 FQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEK 155
++L E +++++ + G +L+ + Q+ A +L+ NE E K + EK
Sbjct: 144 SRQLQEQWEELSSQLFYYGGELQSQKSTEQQL--AAQLVTLQNELELAETKCAL--QEEK 199
Query: 156 IK-------EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLEC-QLIQEFTSAQRRG 207
++ EA I Q+ ++ Q P EV+ K+ +L+ Q +E Q RG
Sbjct: 200 LQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRG 259
>gi|239752137 PREDICTED: hypothetical protein [Homo sapiens]
Length = 357
Score = 40.4 bits (93), Expect = 0.006
Identities = 41/180 (22%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 44 EEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFA--------KKVQELQKSNQVAFQH 95
E +Q+L + + R+ + Q Q EA+E A ++++E ++ + QH
Sbjct: 84 ESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEDLEQH 143
Query: 96 FQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEK 155
++L E +++++ + G +L+ + Q+ A +L+ NE E K + EK
Sbjct: 144 SRQLQEQWEELSSQLFYYGGELQSQKSTEQQL--AAQLVTLQNELELAETKCAL--QEEK 199
Query: 156 IK-------EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLEC-QLIQEFTSAQRRG 207
++ EA I Q+ ++ Q P EV+ K+ +L+ Q +E Q RG
Sbjct: 200 LQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRG 259
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 40.4 bits (93), Expect = 0.006
Identities = 74/370 (20%), Positives = 144/370 (38%), Gaps = 51/370 (13%)
Query: 43 LEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEH 102
LE+ I Q + ++EK EQQ + +EF K+++E + + E +
Sbjct: 439 LEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEF-KQLEE-----AIQLKKISEAGKD 492
Query: 103 ISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKS----DVFTNSEKIKE 158
+ Y L +L+ VN RQ A++ + M+ + + G+ K + +S K+
Sbjct: 493 LLYK-----QLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKD 547
Query: 159 AADIIQKLHLIAQELPFD-----------RFSEVKSKIASKYHDLECQLIQEFTSAQRRG 207
K +E D R E+ S+IA + +++ L ++ T Q
Sbjct: 548 PKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIK-DLEEQLTEGQIAA 606
Query: 208 EISRMREVAAVLLHFKGYSHCVDVYIKQCQ-EGAYLRN----------------DIFEDA 250
+ +++ V+ + Y + Q Q E LR+ D E
Sbjct: 607 NEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIV 666
Query: 251 GILCQRVNKQVGDIFS---NPETVLAKLIQNVFEIKLQSFVKEQLEECRKSDAEQYLKNL 307
+ + + K++ ++ S V A L Q ++ E R ++A Q LK
Sbjct: 667 AMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQ-LKEE 725
Query: 308 YDLYTRTTNLSSKLMEFNLGTDKQTFLSKLIKSIFISYLE---NYIEVETGYLKSRSAMI 364
+ TR T L ++ L ++Q + L K+ F E + + + +L+ + ++
Sbjct: 726 LEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLL 785
Query: 365 LQRYYDSKNH 374
Q+ D +NH
Sbjct: 786 KQQLKDFQNH 795
Score = 30.4 bits (67), Expect = 5.9
Identities = 23/144 (15%), Positives = 66/144 (45%), Gaps = 5/144 (3%)
Query: 48 NHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQEL---DEHIS 104
+++++L++ ++Q+++++L + + + Q+LQ+ + +EL +H++
Sbjct: 1822 SNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLN 1881
Query: 105 YVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADIIQ 164
+ H + + + + R + + ++ N F D + + + ++ +
Sbjct: 1882 LAKQDLLHTTKHQDVLLSEQTRL--QKDISEWANRFEDCQKEEETKQQQLQVLQNEIEEN 1939
Query: 165 KLHLIAQELPFDRFSEVKSKIASK 188
KL L+ QE+ F R + + SK
Sbjct: 1940 KLKLVQQEMMFQRLQKERESEESK 1963
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 40.0 bits (92), Expect = 0.007
Identities = 41/168 (24%), Positives = 76/168 (45%), Gaps = 18/168 (10%)
Query: 40 KRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQEL 99
+R+L+E +L++ E + ++ L++ ++E KEF S+Q+A Q E+
Sbjct: 213 RRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEF---------SSQLAGQVNVEM 263
Query: 100 DEHISYVATKV-CHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKE 158
D T+V + +Q E + +R VEA K EL +V +N+E I+
Sbjct: 264 DAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSK------TEELNKEVASNTEMIQT 317
Query: 159 AADIIQKLHLIAQELPFDRFSE--VKSKIASKYHDLECQLIQEFTSAQ 204
+ I L QEL + S+ +K+ + + + EC+ + Q
Sbjct: 318 SKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQ 365
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 40.0 bits (92), Expect = 0.007
Identities = 67/342 (19%), Positives = 155/342 (45%), Gaps = 17/342 (4%)
Query: 41 RLLEEFVNHI-QELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQEL 99
+ L+++V +ELQ ++++++ + + L ++ KE ++F + +LQ+ N+ QH
Sbjct: 240 KALQQYVQKSKEELQKLEQQLKEQ-KILNERAAKELEQFQMRNAKLQQENE---QHSLVC 295
Query: 100 DEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDG--ELKSDVFTNSEKIK 157
++ K L + E V+ R + K+ + ++ L + K++V + E +K
Sbjct: 296 EQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLK 355
Query: 158 -EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVA 216
+ + +++ ++ DR + ++ + L +++ + Q++ ++ ++ E A
Sbjct: 356 NQIVGLEREVEASKKQAELDR--KAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQA 413
Query: 217 AVLLHFKGYSHCVDVYIKQCQEGAYL---RNDIFEDAGILCQRVNKQVGDIFSNPETVLA 273
L + ++ D KQ + +L R+ A L Q+V + DI ET +
Sbjct: 414 KRNLEGEIQNY-KDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVR-ETQIF 471
Query: 274 KLIQNVFEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRTTNLSSKL--MEFNLGTDKQ 331
+ + E +++ ++ L E +SD Y KNL + T++ KL M + K+
Sbjct: 472 DYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKE 531
Query: 332 TFLSKLIKSIFISYLENYIEVETGYLKSRSAMILQRYYDSKN 373
+K + + + IE E LK+ + Q+ ++K+
Sbjct: 532 DISAKESALVKLHLEQQRIEKEKETLKAELQKLRQQALETKH 573
Score = 36.2 bits (82), Expect = 0.11
Identities = 67/342 (19%), Positives = 136/342 (39%), Gaps = 50/342 (14%)
Query: 38 DPKRLLEEFVNHIQELQIMDERIQRKVEKLE---QQCQKEAKEFAKKVQELQKSNQVAFQ 94
+ + + +F IQ+ Q R RK EKLE +Q Q + +++ LQ+ Q + +
Sbjct: 192 EAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKE 251
Query: 95 HFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSE 154
Q+L++ + +LE + + + E L E N +
Sbjct: 252 ELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQE-------NQQ 304
Query: 155 KIKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMRE 214
K E +++H L + ++++ +I K H E Q + E+ + +E
Sbjct: 305 KALELKAKEEEVH--QMRLDIGKLNKIREQIHKKLHHTEDQ----------KAEVEQHKE 352
Query: 215 VAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAK 274
+ G V+ KQ + +++ + IL + + K V + +T L K
Sbjct: 353 --TLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVN--ATQKQTDLVK 408
Query: 275 LIQNV---FEIKLQSFVKEQLEECRK----------------SD-AEQYLKNLYDLYTRT 314
L + E ++Q++ K++ ++ RK SD ++ L N+ D+ R
Sbjct: 409 LHEQAKRNLEGEIQNY-KDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRE 467
Query: 315 TNL---SSKLMEFNLGTDKQTFLSKLIKSIFISYLENYIEVE 353
T + K+ E + +Q L + ++S Y +N +E +
Sbjct: 468 TQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQ 509
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 38.5 bits (88), Expect = 0.022
Identities = 54/282 (19%), Positives = 113/282 (40%), Gaps = 32/282 (11%)
Query: 42 LLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDE 101
L E I+ L+ +E + + V L Q+ Q A+ +V++++K N++ + +E
Sbjct: 545 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA---RVKDIEKENKILHESIKETSS 601
Query: 102 HISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYF---NEFLDGEL------------- 145
+S + + + +LE +RA E + + + NE L ++
Sbjct: 602 KLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEAL 661
Query: 146 ---KSDVFTNSEKIKEAADIIQKL--HLIAQELPFDRFSEVKSKIASKYHDLECQLIQEF 200
S++ + K+K+ D + L L + E + E ++ L+C ++
Sbjct: 662 EQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA 721
Query: 201 TSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRND----IFEDAGILCQR 256
E+ +E L S ++ +G + N E++ Q+
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 257 VNKQVGDIFSNPETVLAKLIQNVFEIKLQSFVKEQLEECRKS 298
+ ++ D+ +T L +N+ E+K+ S EQLE+ KS
Sbjct: 782 LESELQDLEMENQT----LQKNLEELKISSKRLEQLEKENKS 819
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 38.5 bits (88), Expect = 0.022
Identities = 43/177 (24%), Positives = 81/177 (45%), Gaps = 24/177 (13%)
Query: 51 QELQIMDERIQRKVE---KLEQQCQKEAKEFAKKVQELQKSNQVA---FQHFQELDEHIS 104
QEL + + +K E K+EQ+ + +E ++ +EL SNQ++ Q +EL H S
Sbjct: 179 QELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYS 238
Query: 105 YVATKVCHLGDQLEG----VNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAA 160
+ + H+ G + Q+ E Q L++ +L D+ + + +E
Sbjct: 239 TLEEQRDHVIASKTGAESKITALEQKEQELQALIQ--------QLSIDLQKVTAETQEKE 290
Query: 161 DIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
D+I L QE ++ ++ + H E L++E T A++ E +R + +AA
Sbjct: 291 DVITHL----QEKVASLEKRLEQNLSGEEHVQE--LLKEKTLAEQNLEDTRQQLLAA 341
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 38.5 bits (88), Expect = 0.022
Identities = 40/178 (22%), Positives = 83/178 (46%), Gaps = 23/178 (12%)
Query: 41 RLLEEFVNHIQE-LQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQEL 99
R +EE +QE L++ ++++Q+ + K E + EA E A+++ L K+
Sbjct: 376 RQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEA-ELAQRIAALTKA----------- 423
Query: 100 DEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEK---- 155
+E + ++ HL QLE N QRA + +K+ + N+ L + + ++E+
Sbjct: 424 EERHGNIEERMRHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNERLQLH 483
Query: 156 IKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMR 213
+KE +++ +++ QE + + HD E +L +E + + +MR
Sbjct: 484 LKERMAALEEKNVLIQE-----SETFRKNLEESLHDKE-RLAEEIEKLRSELDQLKMR 535
>gi|169215483 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 356
Score = 38.1 bits (87), Expect = 0.028
Identities = 43/177 (24%), Positives = 79/177 (44%), Gaps = 15/177 (8%)
Query: 44 EEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAK-KVQELQKSNQVAFQHFQELDEH 102
E +Q+L + + R+ + Q Q EA+E A+ + + +++ + A +H ++L++H
Sbjct: 84 ESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEDLEQH 143
Query: 103 ISYVATKVCHLGDQL-EGVNTPRQRAVEAQ---KLMKYFNEFLDGELKSDVFTNSEKIK- 157
+ + L QL G Q++ E Q +L+ NE E K + EK++
Sbjct: 144 SRQLQEQWEELSSQLFYGGEPQSQKSTEQQLAAQLVTLQNELELAETKCAL--QEEKLQQ 201
Query: 158 ------EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLEC-QLIQEFTSAQRRG 207
EA I Q+ ++ Q P EV+ K+ +L+ Q +E Q RG
Sbjct: 202 DALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRG 258
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 37.7 bits (86), Expect = 0.037
Identities = 109/552 (19%), Positives = 216/552 (39%), Gaps = 69/552 (12%)
Query: 40 KRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQV-------- 91
KR LEE L + + + L +Q ++E + A+ + L K+N
Sbjct: 1317 KRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1376
Query: 92 ---AFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSD 148
A Q +EL+E +A ++ +Q+E VN + ++E K + L GE++ D
Sbjct: 1377 ETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNA-KCASLEKTK------QRLQGEVE-D 1428
Query: 149 VFTNSEKIKEAADIIQKLHLIAQELPFDR-FSEVKSKIASKYHDLECQLIQEFTSAQRRG 207
+ + E+ A + K ++ FD+ +E K+K +LE L + + +
Sbjct: 1429 LMVDVERANSLAAALDK-----KQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELF 1483
Query: 208 EISRMREVAAVLLH-FKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDI-- 264
++ E A L K + ++ I E + +++ + DI
Sbjct: 1484 KLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQL 1543
Query: 265 -FSNPETVLAKLIQNVFEIKLQ-SFVKEQLEECRKSDAEQYLKNLYDLYTRTTNLSSKLM 322
E L + I+L+ + VK +++ + ++ ++ ++ L Y RT +
Sbjct: 1544 ALEEAEAALEHEEAKILRIQLELTQVKSEIDR-KIAEKDEEIEQLKRNYQRTVETMQSAL 1602
Query: 323 EFNLGTDKQTF-LSKLIKSIFISYLENYIEVETGYLKSRSAMILQRYYDSKNHQKRS--- 378
+ + + + L K ++ N IE++ + ++A L+ + K +
Sbjct: 1603 DAEVRSRNEAIRLKKKMEGDL-----NEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLH 1657
Query: 379 --IGTGGIQDLKER---IRQRTNLPLGPSIDTHGETFLSQEVVVNLLQETKQAFERCHRL 433
G +DLKE+ + +R NL + V L+ T + ER +L
Sbjct: 1658 LDDALRGQEDLKEQLAIVERRANL---------------LQAEVEELRATLEQTERARKL 1702
Query: 434 SDPSDLPRNAFRIFTILVEFLCIEHIDYALETGLAGIPSS------DSRNANLYFLDVVQ 487
++ L N R+ + + + H LET L + S D+RNA +
Sbjct: 1703 AEQELLDSNE-RVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAIT 1761
Query: 488 QANTIFHLFDKQ--FNDHLMPLISSSPKLSECLQKKKEIIEQMEMKLDTGIDRTLNCMIG 545
A + K+ + HL + + + + LQ + + EQ+ +K + L I
Sbjct: 1762 DAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIR 1821
Query: 546 QMKHILAAEQKK 557
+++ L EQKK
Sbjct: 1822 ELEFELEGEQKK 1833
Score = 31.6 bits (70), Expect = 2.6
Identities = 45/210 (21%), Positives = 88/210 (41%), Gaps = 46/210 (21%)
Query: 38 DPKRLLEEFVNHIQELQIMDERIQRKVE---KLEQQCQKEAKEFAKKVQELQK------- 87
D + L +F I+ELQ E ++ ++E + +K+ ++A++++EL +
Sbjct: 1097 DEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGG 1156
Query: 88 --SNQVAFQHFQELD-------------EHISYVAT-------KVCHLGDQLEGVNTPRQ 125
S Q+ +E + +H + VA V LG+Q++ + +
Sbjct: 1157 VTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVK- 1215
Query: 126 RAVEAQKLMKYFNEFLDGELKSDVFTNS-EKIKEAADIIQKLHLIAQELPFDRFSEVKSK 184
QKL K +EF +L+ D ++S E + ++ ++K+ + D+ SE + K
Sbjct: 1216 -----QKLEKEKSEF---KLEIDDLSSSMESVSKSKANLEKICRTLE----DQLSEARGK 1263
Query: 185 IASKYHDLECQLIQEFTSAQRRGEISRMRE 214
L Q+ GE+SR E
Sbjct: 1264 NEEIQRSLSELTTQKSRLQTEAGELSRQLE 1293
Score = 30.8 bits (68), Expect = 4.5
Identities = 71/357 (19%), Positives = 143/357 (40%), Gaps = 53/357 (14%)
Query: 40 KRLLEEFVNHIQELQIMDERIQRKVEKL---EQQCQK----------EAKEFAKKVQELQ 86
K L E+ V +QE + ++Q + E L E++C + + KE ++ ++ +
Sbjct: 872 KELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEE 931
Query: 87 KSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDG--- 143
+ N ++L++ S + + L L V + + +K E L G
Sbjct: 932 EINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT---ENKVKNLTEELSGLDE 988
Query: 144 ---ELKSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEF 200
+L + E ++A D +Q A+E + ++ KSK+ + DLE L QE
Sbjct: 989 TIAKLTREKKALQEAHQQALDDLQ-----AEEDKVNSLNKTKSKLEQQVEDLESSLEQE- 1042
Query: 201 TSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNK- 259
+ R ++ R + ++ +K QE D+ D L +R+ K
Sbjct: 1043 --KKLRVDLERNKRK-------------LEGDLKLAQESIL---DLENDKQQLDERLKKK 1084
Query: 260 -----QVGDIFSNPETVLAKLIQNVFEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRT 314
Q+ + +T+ + + + E++ + E+ E ++ + K D
Sbjct: 1085 DFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYAREL 1144
Query: 315 TNLSSKLMEFNLGTDKQTFLSKLIKSIFISYLENYIEVETGYLKSRSAMILQRYYDS 371
LS +L E T Q L+K ++ F+ L +E T ++ A + +++ DS
Sbjct: 1145 EELSERLEEAGGVTSTQIELNKKREAEFLK-LRRDLEEATLQHEAMVAALRKKHADS 1200
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 37.7 bits (86), Expect = 0.037
Identities = 82/392 (20%), Positives = 150/392 (38%), Gaps = 72/392 (18%)
Query: 52 ELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVC 111
EL + ++ K ++L Q E + +++EL + NQ A +H + + +S
Sbjct: 468 ELHDLRLNLEAKEQELNQSIS-EKETLIAEIEELDRQNQEATKHMILIKDQLS------- 519
Query: 112 HLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADI-IQKLHLIA 170
++ E ++ + L+ E K +K+ ++ +QK LI
Sbjct: 520 -------------KQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQ 566
Query: 171 QELPFDRFSEVKSKIASKYHDLECQLIQEFTS---------------AQRRGEISRMREV 215
E+ + K K+ K +L QL + S Q E+SR+R
Sbjct: 567 SEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNE 626
Query: 216 AAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDI-FSNPETVLAK 274
L+ S+ D +K+ + + L + + K D+ N + VLA
Sbjct: 627 LMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLA- 685
Query: 275 LIQNVFEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRTTNLSSKLMEFNLGTDKQTFL 334
V+ QLEEC + + L+ + T + +E L K+ L
Sbjct: 686 ----------CEDVRHQLEECLAGNNQLSLEK--NTIVETLKMEKGEIEAELCWAKKRLL 733
Query: 335 SKLIKSIFISYLENYIEVETGYLKSRSAMILQRYYDSKNHQKRSIGTGGIQDLKERIRQR 394
+ K Y + E+ + SA+ L+ + K +QK+ + I +LK+ I Q
Sbjct: 734 EEANK-----YEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDM---EIAELKKNIEQ- 784
Query: 395 TNLPLGPSIDT-HGETFLSQEVVVNLLQETKQ 425
+DT H ET ++V+ + L+E KQ
Sbjct: 785 --------MDTDHKET---KDVLSSSLEEQKQ 805
Score = 33.5 bits (75), Expect = 0.70
Identities = 23/92 (25%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 38 DPKRLLEEFVNHIQELQIMDERIQRK---VEKLEQQCQKEAKEFAKKVQELQKSNQVAFQ 94
D K + + ++E + + + I +K +EKL+++ K +E K Q L+K N++ Q
Sbjct: 788 DHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRK-NEILRQ 846
Query: 95 HFQELDEHISYVATKVCHLGDQLEGVNTPRQR 126
+E D + + + HL ++LE + + R
Sbjct: 847 TIEEKDRSLGSMKEENNHLQEELERLREEQSR 878
Score = 30.8 bits (68), Expect = 4.5
Identities = 46/206 (22%), Positives = 85/206 (41%), Gaps = 20/206 (9%)
Query: 40 KRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQEL 99
K LEE + H Q +I++++ Q K++ L Q Q++ KE + + ++ N Q F E
Sbjct: 905 KEHLEEEIKHHQ--KIIEDQNQSKMQLL-QSLQEQKKEMDEFRYQHEQMNATHTQLFLEK 961
Query: 100 DEHISYVATKVCHLGDQL----EGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEK 155
DE I + + + QL + + T + K+ E +G K D+ + +E
Sbjct: 962 DEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIE--NGSEKHDL-SKAET 1018
Query: 156 IKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREV 215
+ I ++ EL +E + + L + + T ++ ++ E+
Sbjct: 1019 ERLVKGIKER------ELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDL----EI 1068
Query: 216 AAVLLHFKGYSHCVDVYIKQCQEGAY 241
A+ SH DV Q Q AY
Sbjct: 1069 QALHARISSTSHTQDVVYLQQQLQAY 1094
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 37.4 bits (85), Expect = 0.048
Identities = 76/393 (19%), Positives = 166/393 (42%), Gaps = 72/393 (18%)
Query: 40 KRLLE----EFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFA----------KKVQEL 85
KR LE E I +L++ +++++ E + + +E A K+ + L
Sbjct: 943 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002
Query: 86 QKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGEL 145
Q+++Q Q ++ ++ + L Q++ + ++ + + ++ L+G+L
Sbjct: 1003 QETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1062
Query: 146 K----------SDVFTNSEKIK----EAADIIQKLH-LIAQELPFD-RFSEVKSKIASKY 189
K +D EK++ E +++I K+ A E+ + E++++I
Sbjct: 1063 KLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELG 1122
Query: 190 HDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAY--LRNDIF 247
++E + + ++R ++SR E + L G + V + + +E + LR D+
Sbjct: 1123 EEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLE 1182
Query: 248 E-----DAGILCQRVN-----KQVGDIFSNPETVLAKLIQNVFEIKLQ-----------S 286
E +A + R ++G+ N + V KL + E+K++ S
Sbjct: 1183 EATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAIS 1242
Query: 287 FVKEQLEE-CR---------KSDAEQYLKNLYDLYTRTTNLSSKLMEFNLGTDKQTFL-- 334
K LE+ CR K+ E+ + + DL + L ++ E++ D++ L
Sbjct: 1243 KAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVS 1302
Query: 335 ----SKLIKSIFISYLENYIEVETGYLKSRSAM 363
SK + I L++ +E ET K+++A+
Sbjct: 1303 QLSRSKQASTQQIEELKHQLEEET---KAKNAL 1332
Score = 35.0 bits (79), Expect = 0.24
Identities = 35/161 (21%), Positives = 74/161 (45%), Gaps = 9/161 (5%)
Query: 48 NHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVA 107
N + +LQ E + ++ E++ +K + A +EL+K + H + + +++
Sbjct: 1735 NDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTS-AHLERMKKNLEQTV 1793
Query: 108 TKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAADIIQKLH 167
+ H D+ E + + + QKL E L+GE++++ N+E +K ++K
Sbjct: 1794 KDLQHRLDEAEQLALKGGKK-QIQKLEARVRE-LEGEVENEQKRNAEAVKG----LRKHE 1847
Query: 168 LIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGE 208
+EL + +E K + DL +L + S +R+ E
Sbjct: 1848 RRVKELTYQ--TEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 37.0 bits (84), Expect = 0.063
Identities = 43/190 (22%), Positives = 91/190 (47%), Gaps = 28/190 (14%)
Query: 40 KRLLEEFVNHIQELQIMD-ERIQRKVE----KLEQQCQKEAKEFAKKVQELQ-KSNQVAF 93
K +L + I++ QI++ ++IQ++++ +L+Q + E ++ ++ +EL+ K +
Sbjct: 196 KIILNAKCHAIRDAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERI 255
Query: 94 QHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNS 153
+ +++ E + +Q E QR E +++++Y + + +LK
Sbjct: 256 RGRRQIVEQMEK---------NQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQ 306
Query: 154 EKIKEAADI--------IQKLHLIAQELPFDR--FSEVKSKIASKYHDLECQLIQEFTSA 203
+K+K A+I QK L+AQE D+ K K+A + E + QE
Sbjct: 307 QKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMA---REAEFEAEQERIRR 363
Query: 204 QRRGEISRMR 213
++ EI+R+R
Sbjct: 364 EKEKEIARLR 373
>gi|170932494 syntaxin 7 [Homo sapiens]
Length = 261
Score = 36.6 bits (83), Expect = 0.082
Identities = 56/245 (22%), Positives = 99/245 (40%), Gaps = 37/245 (15%)
Query: 25 TPGGGSRGGPEAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQE 84
TPG G DP +L + ++IQ++ IQR + +L ++ + Q+
Sbjct: 4 TPGVGG-------DPAQLAQRISSNIQKITQCSVEIQRTLNQL-----GTPQDSPELRQQ 51
Query: 85 LQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGE 144
LQ+ Q Q +E D++I G + RQR ++ +L+ F L
Sbjct: 52 LQQKQQYTNQLAKETDKYIK-------EFGSLPTTPSEQRQRKIQKDRLVAEFTTSL--- 101
Query: 145 LKSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQ 204
TN +K++ A +K +A+ R S + +SK +L Q T Q
Sbjct: 102 ------TNFQKVQRQAAEREK-EFVARVRASSRVSGSFPEDSSKERNLVSWESQ--TQPQ 152
Query: 205 RRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDI 264
+ + + E L+H + S I+Q + N+IF+D G++ + I
Sbjct: 153 VQVQDEEITEDDLRLIHERESS------IRQLEADIMDINEIFKDLGMMIHEQGDVIDSI 206
Query: 265 FSNPE 269
+N E
Sbjct: 207 EANVE 211
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 36.6 bits (83), Expect = 0.082
Identities = 66/272 (24%), Positives = 119/272 (43%), Gaps = 32/272 (11%)
Query: 40 KRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQEL 99
+R E+ + LQI +E + +V+++ Q ++ A + +K QE++ + Q EL
Sbjct: 460 RRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDEL 519
Query: 100 DEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEA 159
+ + + T L E N ++RA E L+ + GE+ + TN +K
Sbjct: 520 AQKTTTLTTTQRELSQLQELSNHQKKRATEILNLL--LKDL--GEIGGIIGTND--VKTL 573
Query: 160 ADIIQKLHLIAQELPFDR--FSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
AD+ +I +E R S++KS++ S + + QL + R+ S RE+AA
Sbjct: 574 ADV---NGVIEEEFTMARLYISKMKSEVKSLVNRSK-QLESAQMDSNRKMNASE-RELAA 628
Query: 218 VLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKL-- 275
L + + IK + Y++N ++ +Q+ + + LAKL
Sbjct: 629 CQLLISQH----EAKIKSLTD--YMQN---------MEQKRRQLEESQDSLSEELAKLRA 673
Query: 276 IQNVFEIKLQSFVKEQLEECRKSDAEQYLKNL 307
+ + E+ Q KE L R DAE+ K L
Sbjct: 674 QEKMHEVSFQDKEKEHL--TRLQDAEEMKKAL 703
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 36.6 bits (83), Expect = 0.082
Identities = 52/247 (21%), Positives = 101/247 (40%), Gaps = 37/247 (14%)
Query: 7 LFEEPFVADEYIERLVWRTPGGGSRGGPEAFDPKRLLEEFVNHIQELQIMDERIQRKVEK 66
L EE ++ Y E R +A R LEE + +E + +++++ +E
Sbjct: 1457 LAEEKSISARYAEERD-RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED 1515
Query: 67 LEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQR 126
L + K V EL+KS + L++ + + T++ L D+L+ + R
Sbjct: 1516 L----MSSKDDVGKNVHELEKSKRA-------LEQQVEEMRTQLEELEDELQATEDAKLR 1564
Query: 127 AVEAQKLMKYFNEFLDGELKSDVFTNSEKIKEAAD-IIQKLHLIAQELPFDRFSEV---- 181
+ MK + + D+ T E+ +E +I+++ + EL +R
Sbjct: 1565 LEVNMQAMK-------AQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 182 -KSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGA 240
K K+ DLE Q+ E + R I ++R++ A + Y ++ +E
Sbjct: 1618 SKKKMEIDLKDLEAQI--EAANKARDEVIKQLRKLQAQMKD----------YQRELEEAR 1665
Query: 241 YLRNDIF 247
R++IF
Sbjct: 1666 ASRDEIF 1672
Score = 35.0 bits (79), Expect = 0.24
Identities = 35/179 (19%), Positives = 76/179 (42%), Gaps = 6/179 (3%)
Query: 35 EAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQ 94
+ + K +L E + EL E ++ ++ +Q+ ++ + +V+E ++ NQ+
Sbjct: 884 QLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQN 943
Query: 95 HFQELDEHISYVATKVCHLGDQLEGVNTPRQ--RAVEAQKLMKYFNEFLDGELKSDVFTN 152
+++ HI + ++ D+ EG Q + K+ K E L E ++ F
Sbjct: 944 EKKKMQAHIQDLEEQL----DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIK 999
Query: 153 SEKIKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISR 211
+K+ E L +E +++++K DLE +L +E + Q + R
Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 1058
Score = 33.1 bits (74), Expect = 0.91
Identities = 56/245 (22%), Positives = 100/245 (40%), Gaps = 38/245 (15%)
Query: 40 KRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQK-----------------EAKEFAKKV 82
K L EE NH ++Q M +R +E+L +Q ++ + KE A +V
Sbjct: 1181 KALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEV 1240
Query: 83 QELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLD 142
+ LQ+ + ++LD + + KV GD+L R A+K K NE
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQVQELHAKVSE-GDRL--------RVELAEKASKLQNEL-- 1289
Query: 143 GELKSDVFTNSEK-----IKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQ-- 195
+ S + +EK K+AA + +L QEL + K ++S+ LE +
Sbjct: 1290 -DNVSTLLEEAEKKGIKFAKDAASLESQLQ-DTQEL-LQEETRQKLNLSSRIRQLEEEKN 1346
Query: 196 LIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQ 255
+QE + + ++V A+ VD + + + + +DA L Q
Sbjct: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQ 1406
Query: 256 RVNKQ 260
R+ ++
Sbjct: 1407 RLEEK 1411
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 36.6 bits (83), Expect = 0.082
Identities = 55/266 (20%), Positives = 115/266 (43%), Gaps = 29/266 (10%)
Query: 41 RLLEEFVNHIQE-LQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQEL 99
R E+ +QE L++ ++++Q+ + K E + EA E A++V L K+
Sbjct: 358 RQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEA-ELAQRVAALSKA----------- 405
Query: 100 DEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEK---- 155
+E + ++ + QLE N QRA + +K+ + N+ L + + ++E+
Sbjct: 406 EERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLH 465
Query: 156 IKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREV 215
+KE ++ + + +E+ K ++ HD + QL+ + R E+ MR
Sbjct: 466 LKERMAALEDKNSLLREV-----ESAKKQLEETQHDKD-QLVLNIEAL--RAELDHMRLR 517
Query: 216 AAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKL 275
A L H + + V + +G D + + +L + ++ + P V L
Sbjct: 518 GASLHHGRPHLGSVPDFRFPMADG---HTDSYSTSAVLRRPQKGRLAALRDEPSKV-QTL 573
Query: 276 IQNVFEIKLQSFVKEQLEECRKSDAE 301
+ +E Q+ V + + +SDA+
Sbjct: 574 NEQDWERAQQASVLANVAQAFESDAD 599
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 36.6 bits (83), Expect = 0.082
Identities = 55/266 (20%), Positives = 115/266 (43%), Gaps = 29/266 (10%)
Query: 41 RLLEEFVNHIQE-LQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQEL 99
R E+ +QE L++ ++++Q+ + K E + EA E A++V L K+
Sbjct: 358 RQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEA-ELAQRVAALSKA----------- 405
Query: 100 DEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEK---- 155
+E + ++ + QLE N QRA + +K+ + N+ L + + ++E+
Sbjct: 406 EERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLH 465
Query: 156 IKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREV 215
+KE ++ + + +E+ K ++ HD + QL+ + R E+ MR
Sbjct: 466 LKERMAALEDKNSLLREV-----ESAKKQLEETQHDKD-QLVLNIEAL--RAELDHMRLR 517
Query: 216 AAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKL 275
A L H + + V + +G D + + +L + ++ + P V L
Sbjct: 518 GASLHHGRPHLGSVPDFRFPMADG---HTDSYSTSAVLRRPQKGRLAALRDEPSKV-QTL 573
Query: 276 IQNVFEIKLQSFVKEQLEECRKSDAE 301
+ +E Q+ V + + +SDA+
Sbjct: 574 NEQDWERAQQASVLANVAQAFESDAD 599
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 36.2 bits (82), Expect = 0.11
Identities = 38/184 (20%), Positives = 77/184 (41%), Gaps = 5/184 (2%)
Query: 43 LEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEH 102
L E N +QE + + + E++ + + +E + + E++ + Q+L
Sbjct: 885 LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE 944
Query: 103 ISYVATKVCHLGDQLEGVNTPRQ-----RAVEAQKLMKYFNEFLDGELKSDVFTNSEKIK 157
+A ++ L +QLE RQ + K+ K +E L + +++ + K+
Sbjct: 945 RKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1004
Query: 158 EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
E +L +E +++K+K S +LE +L +E S Q ++ R E A
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1064
Query: 218 VLLH 221
H
Sbjct: 1065 SDFH 1068
Score = 36.2 bits (82), Expect = 0.11
Identities = 51/223 (22%), Positives = 95/223 (42%), Gaps = 38/223 (17%)
Query: 35 EAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQ 94
+A R LEE + +EL+ ++ ++ ++E L + K V EL+KS +
Sbjct: 1484 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSS----KDDVGKNVHELEKSKRA--- 1536
Query: 95 HFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFN-EFLDGELKSDVFTNS 153
L+ + + T++ L D+L+ A E KL N + L G+ + D+
Sbjct: 1537 ----LETQMEEMKTQLEELEDELQ--------ATEDAKLRLEVNMQALKGQFERDLQARD 1584
Query: 154 EKIKEAADIIQK-LHLIAQELPFDR-----FSEVKSKIASKYHDLECQLIQEFTSAQRRG 207
E+ +E +Q+ LH EL +R + K K+ DLE Q + R
Sbjct: 1585 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ--ADSAIKGREE 1642
Query: 208 EISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDA 250
I ++R++ A + F+ ++ ++ R++IF A
Sbjct: 1643 AIKQLRKLQAQMKDFQ----------RELEDARASRDEIFATA 1675
Score = 33.9 bits (76), Expect = 0.53
Identities = 53/281 (18%), Positives = 128/281 (45%), Gaps = 25/281 (8%)
Query: 41 RLLEEFVNHIQELQIM---DERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQ 97
+L + + I EL++ +E+ ++++EKL+++ + +A +F +++ +LQ Q+A Q
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA--QIAELKMQ 1084
Query: 98 ELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIK 157
L + + + L D++ N ++ E + + E LD E + ++ K
Sbjct: 1085 -LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA----RNKAEK 1139
Query: 158 EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
+ D+ ++L + EL S + + E ++++ + R ++++E+
Sbjct: 1140 QKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR- 1198
Query: 218 VLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQ 277
+ ++ V+ +Q ++ + ++ ++ Q + K+ D+ + VL + Q
Sbjct: 1199 -----QKHAQAVEELTEQLEQFKRAKANLDKNK----QTLEKENADL-AGELRVLGQAKQ 1248
Query: 278 NV--FEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRTTN 316
V + KL++ V+E +C SD E+ L D + N
Sbjct: 1249 EVEHKKKKLEAQVQELQSKC--SDGERARAELNDKVHKLQN 1287
Score = 30.0 bits (66), Expect = 7.7
Identities = 37/187 (19%), Positives = 78/187 (41%), Gaps = 22/187 (11%)
Query: 38 DPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQ 97
D +R E + + +LQ E + + + E + K AK+ A +LQ + ++ Q
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL----LQ 1325
Query: 98 ELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELK------SDVFT 151
E V+TK+ L ++ + +EA++ ++ L+ +L D +
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1385
Query: 152 NSEKIKEAADIIQK-LHLIAQE-----LPFDRFSEVKSKIASKYHDL------ECQLIQE 199
E ++E QK + + Q+ +D+ + K+++ + DL + QL+
Sbjct: 1386 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1445
Query: 200 FTSAQRR 206
QR+
Sbjct: 1446 LEKKQRK 1452
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 36.2 bits (82), Expect = 0.11
Identities = 38/184 (20%), Positives = 77/184 (41%), Gaps = 5/184 (2%)
Query: 43 LEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEH 102
L E N +QE + + + E++ + + +E + + E++ + Q+L
Sbjct: 892 LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE 951
Query: 103 ISYVATKVCHLGDQLEGVNTPRQ-----RAVEAQKLMKYFNEFLDGELKSDVFTNSEKIK 157
+A ++ L +QLE RQ + K+ K +E L + +++ + K+
Sbjct: 952 RKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1011
Query: 158 EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
E +L +E +++K+K S +LE +L +E S Q ++ R E A
Sbjct: 1012 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1071
Query: 218 VLLH 221
H
Sbjct: 1072 SDFH 1075
Score = 36.2 bits (82), Expect = 0.11
Identities = 51/223 (22%), Positives = 95/223 (42%), Gaps = 38/223 (17%)
Query: 35 EAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQ 94
+A R LEE + +EL+ ++ ++ ++E L + K V EL+KS +
Sbjct: 1491 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSS----KDDVGKNVHELEKSKRA--- 1543
Query: 95 HFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFN-EFLDGELKSDVFTNS 153
L+ + + T++ L D+L+ A E KL N + L G+ + D+
Sbjct: 1544 ----LETQMEEMKTQLEELEDELQ--------ATEDAKLRLEVNMQALKGQFERDLQARD 1591
Query: 154 EKIKEAADIIQK-LHLIAQELPFDR-----FSEVKSKIASKYHDLECQLIQEFTSAQRRG 207
E+ +E +Q+ LH EL +R + K K+ DLE Q + R
Sbjct: 1592 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ--ADSAIKGREE 1649
Query: 208 EISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDA 250
I ++R++ A + F+ ++ ++ R++IF A
Sbjct: 1650 AIKQLRKLQAQMKDFQ----------RELEDARASRDEIFATA 1682
Score = 33.9 bits (76), Expect = 0.53
Identities = 53/281 (18%), Positives = 128/281 (45%), Gaps = 25/281 (8%)
Query: 41 RLLEEFVNHIQELQIM---DERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQ 97
+L + + I EL++ +E+ ++++EKL+++ + +A +F +++ +LQ Q+A Q
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA--QIAELKMQ 1091
Query: 98 ELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIK 157
L + + + L D++ N ++ E + + E LD E + ++ K
Sbjct: 1092 -LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA----RNKAEK 1146
Query: 158 EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
+ D+ ++L + EL S + + E ++++ + R ++++E+
Sbjct: 1147 QKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR- 1205
Query: 218 VLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQ 277
+ ++ V+ +Q ++ + ++ ++ Q + K+ D+ + VL + Q
Sbjct: 1206 -----QKHAQAVEELTEQLEQFKRAKANLDKNK----QTLEKENADL-AGELRVLGQAKQ 1255
Query: 278 NV--FEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRTTN 316
V + KL++ V+E +C SD E+ L D + N
Sbjct: 1256 EVEHKKKKLEAQVQELQSKC--SDGERARAELNDKVHKLQN 1294
Score = 30.0 bits (66), Expect = 7.7
Identities = 37/187 (19%), Positives = 78/187 (41%), Gaps = 22/187 (11%)
Query: 38 DPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQ 97
D +R E + + +LQ E + + + E + K AK+ A +LQ + ++ Q
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL----LQ 1332
Query: 98 ELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELK------SDVFT 151
E V+TK+ L ++ + +EA++ ++ L+ +L D +
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1392
Query: 152 NSEKIKEAADIIQK-LHLIAQE-----LPFDRFSEVKSKIASKYHDL------ECQLIQE 199
E ++E QK + + Q+ +D+ + K+++ + DL + QL+
Sbjct: 1393 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1452
Query: 200 FTSAQRR 206
QR+
Sbjct: 1453 LEKKQRK 1459
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 36.2 bits (82), Expect = 0.11
Identities = 38/184 (20%), Positives = 77/184 (41%), Gaps = 5/184 (2%)
Query: 43 LEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEH 102
L E N +QE + + + E++ + + +E + + E++ + Q+L
Sbjct: 892 LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE 951
Query: 103 ISYVATKVCHLGDQLEGVNTPRQ-----RAVEAQKLMKYFNEFLDGELKSDVFTNSEKIK 157
+A ++ L +QLE RQ + K+ K +E L + +++ + K+
Sbjct: 952 RKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1011
Query: 158 EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
E +L +E +++K+K S +LE +L +E S Q ++ R E A
Sbjct: 1012 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1071
Query: 218 VLLH 221
H
Sbjct: 1072 SDFH 1075
Score = 36.2 bits (82), Expect = 0.11
Identities = 51/223 (22%), Positives = 95/223 (42%), Gaps = 38/223 (17%)
Query: 35 EAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQ 94
+A R LEE + +EL+ ++ ++ ++E L + K V EL+KS +
Sbjct: 1491 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSS----KDDVGKNVHELEKSKRA--- 1543
Query: 95 HFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFN-EFLDGELKSDVFTNS 153
L+ + + T++ L D+L+ A E KL N + L G+ + D+
Sbjct: 1544 ----LETQMEEMKTQLEELEDELQ--------ATEDAKLRLEVNMQALKGQFERDLQARD 1591
Query: 154 EKIKEAADIIQK-LHLIAQELPFDR-----FSEVKSKIASKYHDLECQLIQEFTSAQRRG 207
E+ +E +Q+ LH EL +R + K K+ DLE Q + R
Sbjct: 1592 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ--ADSAIKGREE 1649
Query: 208 EISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDA 250
I ++R++ A + F+ ++ ++ R++IF A
Sbjct: 1650 AIKQLRKLQAQMKDFQ----------RELEDARASRDEIFATA 1682
Score = 33.9 bits (76), Expect = 0.53
Identities = 53/281 (18%), Positives = 128/281 (45%), Gaps = 25/281 (8%)
Query: 41 RLLEEFVNHIQELQIM---DERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQ 97
+L + + I EL++ +E+ ++++EKL+++ + +A +F +++ +LQ Q+A Q
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA--QIAELKMQ 1091
Query: 98 ELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIK 157
L + + + L D++ N ++ E + + E LD E + ++ K
Sbjct: 1092 -LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA----RNKAEK 1146
Query: 158 EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
+ D+ ++L + EL S + + E ++++ + R ++++E+
Sbjct: 1147 QKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR- 1205
Query: 218 VLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQ 277
+ ++ V+ +Q ++ + ++ ++ Q + K+ D+ + VL + Q
Sbjct: 1206 -----QKHAQAVEELTEQLEQFKRAKANLDKNK----QTLEKENADL-AGELRVLGQAKQ 1255
Query: 278 NV--FEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRTTN 316
V + KL++ V+E +C SD E+ L D + N
Sbjct: 1256 EVEHKKKKLEAQVQELQSKC--SDGERARAELNDKVHKLQN 1294
Score = 30.0 bits (66), Expect = 7.7
Identities = 37/187 (19%), Positives = 78/187 (41%), Gaps = 22/187 (11%)
Query: 38 DPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQ 97
D +R E + + +LQ E + + + E + K AK+ A +LQ + ++ Q
Sbjct: 1277 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL----LQ 1332
Query: 98 ELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELK------SDVFT 151
E V+TK+ L ++ + +EA++ ++ L+ +L D +
Sbjct: 1333 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1392
Query: 152 NSEKIKEAADIIQK-LHLIAQE-----LPFDRFSEVKSKIASKYHDL------ECQLIQE 199
E ++E QK + + Q+ +D+ + K+++ + DL + QL+
Sbjct: 1393 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1452
Query: 200 FTSAQRR 206
QR+
Sbjct: 1453 LEKKQRK 1459
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 36.2 bits (82), Expect = 0.11
Identities = 38/184 (20%), Positives = 77/184 (41%), Gaps = 5/184 (2%)
Query: 43 LEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQELDEH 102
L E N +QE + + + E++ + + +E + + E++ + Q+L
Sbjct: 885 LTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE 944
Query: 103 ISYVATKVCHLGDQLEGVNTPRQ-----RAVEAQKLMKYFNEFLDGELKSDVFTNSEKIK 157
+A ++ L +QLE RQ + K+ K +E L + +++ + K+
Sbjct: 945 RKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1004
Query: 158 EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
E +L +E +++K+K S +LE +L +E S Q ++ R E A
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1064
Query: 218 VLLH 221
H
Sbjct: 1065 SDFH 1068
Score = 36.2 bits (82), Expect = 0.11
Identities = 51/223 (22%), Positives = 95/223 (42%), Gaps = 38/223 (17%)
Query: 35 EAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQ 94
+A R LEE + +EL+ ++ ++ ++E L + K V EL+KS +
Sbjct: 1484 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSS----KDDVGKNVHELEKSKRA--- 1536
Query: 95 HFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFN-EFLDGELKSDVFTNS 153
L+ + + T++ L D+L+ A E KL N + L G+ + D+
Sbjct: 1537 ----LETQMEEMKTQLEELEDELQ--------ATEDAKLRLEVNMQALKGQFERDLQARD 1584
Query: 154 EKIKEAADIIQK-LHLIAQELPFDR-----FSEVKSKIASKYHDLECQLIQEFTSAQRRG 207
E+ +E +Q+ LH EL +R + K K+ DLE Q + R
Sbjct: 1585 EQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ--ADSAIKGREE 1642
Query: 208 EISRMREVAAVLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDA 250
I ++R++ A + F+ ++ ++ R++IF A
Sbjct: 1643 AIKQLRKLQAQMKDFQ----------RELEDARASRDEIFATA 1675
Score = 33.9 bits (76), Expect = 0.53
Identities = 53/281 (18%), Positives = 128/281 (45%), Gaps = 25/281 (8%)
Query: 41 RLLEEFVNHIQELQIM---DERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQ 97
+L + + I EL++ +E+ ++++EKL+++ + +A +F +++ +LQ Q+A Q
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQA--QIAELKMQ 1084
Query: 98 ELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELKSDVFTNSEKIK 157
L + + + L D++ N ++ E + + E LD E + ++ K
Sbjct: 1085 -LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA----RNKAEK 1139
Query: 158 EAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAA 217
+ D+ ++L + EL S + + E ++++ + R ++++E+
Sbjct: 1140 QKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR- 1198
Query: 218 VLLHFKGYSHCVDVYIKQCQEGAYLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQ 277
+ ++ V+ +Q ++ + ++ ++ Q + K+ D+ + VL + Q
Sbjct: 1199 -----QKHAQAVEELTEQLEQFKRAKANLDKNK----QTLEKENADL-AGELRVLGQAKQ 1248
Query: 278 NV--FEIKLQSFVKEQLEECRKSDAEQYLKNLYDLYTRTTN 316
V + KL++ V+E +C SD E+ L D + N
Sbjct: 1249 EVEHKKKKLEAQVQELQSKC--SDGERARAELNDKVHKLQN 1287
Score = 30.0 bits (66), Expect = 7.7
Identities = 37/187 (19%), Positives = 78/187 (41%), Gaps = 22/187 (11%)
Query: 38 DPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQELQKSNQVAFQHFQ 97
D +R E + + +LQ E + + + E + K AK+ A +LQ + ++ Q
Sbjct: 1270 DGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQEL----LQ 1325
Query: 98 ELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDGELK------SDVFT 151
E V+TK+ L ++ + +EA++ ++ L+ +L D +
Sbjct: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1385
Query: 152 NSEKIKEAADIIQK-LHLIAQE-----LPFDRFSEVKSKIASKYHDL------ECQLIQE 199
E ++E QK + + Q+ +D+ + K+++ + DL + QL+
Sbjct: 1386 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1445
Query: 200 FTSAQRR 206
QR+
Sbjct: 1446 LEKKQRK 1452
>gi|157427195 hypothetical protein LOC347475 [Homo sapiens]
Length = 325
Score = 36.2 bits (82), Expect = 0.11
Identities = 46/200 (23%), Positives = 85/200 (42%), Gaps = 26/200 (13%)
Query: 35 EAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKK---VQELQKSNQV 91
E PK L ++EL + +I+ + E E++ KE K QE +
Sbjct: 139 ERMSPKLCLNLLNEELEELNMKYRKIEEEFENAEKELLHYKKEIFTKPLNFQETETDASK 198
Query: 92 AFQHFQELDEHISYVATKVCHLGDQLE-------GVNTPRQRAVEAQKLMKYFNEFLDGE 144
+ Q L +S AT V +L +QL+ +N + EA + +K+ E +
Sbjct: 199 SDYELQALRNDLSEKATNVKNLSEQLQQAKEVIHKLNLENRNLKEAVRKLKHQTEVGNVL 258
Query: 145 LKSDVFTNSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFTSAQ 204
LK ++ + E E A I +L +I EL ++ + ++ A +L++++ +
Sbjct: 259 LKEEMKSYYE--LEMAKIRGELSVIKNELRTEKTLQARNNRA-------LELLRKYYA-- 307
Query: 205 RRGEISRMREVAAVLLHFKG 224
S M +++L HF G
Sbjct: 308 -----SSMVTSSSILDHFTG 322
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 36.2 bits (82), Expect = 0.11
Identities = 34/166 (20%), Positives = 70/166 (42%), Gaps = 12/166 (7%)
Query: 44 EEFVNHIQELQIMDERIQRKVEKLEQQCQKEAKEFAKKVQ----ELQKSNQVAFQHFQEL 99
E F IQ+LQ ++ ++ LE + + E KE +++ E+Q Q A E
Sbjct: 105 EVFTKQIQQLQGELRSLREEISLLEHEKESELKEIEQELHLAQAEIQSLRQAAEDSATEH 164
Query: 100 DEHISYVATKVCHLGDQLEGVNTPR----QRAVEAQKLMKYFNEFLDGELKSDVFTNSEK 155
+ I+ + +C + ++LE + R + M+ + G L ++ +
Sbjct: 165 ESDIASLQEDLCRMQNELEDMERIRGDYEMEIASLRAEMEMKSSEPSGSLGLSDYSGLQ- 223
Query: 156 IKEAADIIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQEFT 201
+E ++ ++ H + +E + E S + + DLE + Q T
Sbjct: 224 -EELQELRERYHFLNEE--YRALQESNSSLTGQLADLESERTQRAT 266
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,978,730
Number of Sequences: 37866
Number of extensions: 1094558
Number of successful extensions: 5450
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 190
Number of HSP's that attempted gapping in prelim test: 4820
Number of HSP's gapped (non-prelim): 810
length of query: 708
length of database: 18,247,518
effective HSP length: 109
effective length of query: 599
effective length of database: 14,120,124
effective search space: 8457954276
effective search space used: 8457954276
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.