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Search of human proteins with 57242805
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|57242805 tyrosyl-DNA phosphodiesterase 1 [Homo sapiens]
(608 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57242805 tyrosyl-DNA phosphodiesterase 1 [Homo sapiens] 1264 0.0
gi|20127586 tyrosyl-DNA phosphodiesterase 1 [Homo sapiens] 1264 0.0
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 41 0.004
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 41 0.004
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 38 0.031
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 35 0.20
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 35 0.20
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 35 0.26
gi|151301228 formin binding protein 3 [Homo sapiens] 33 0.76
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 33 1.00
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 32 1.7
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 32 1.7
gi|189011568 adenomatous polyposis coli [Homo sapiens] 32 2.2
gi|189011566 adenomatous polyposis coli [Homo sapiens] 32 2.2
gi|53759122 adenomatous polyposis coli [Homo sapiens] 32 2.2
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 32 2.2
gi|56676330 HP1-BP74 [Homo sapiens] 32 2.2
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 32 2.2
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 32 2.2
gi|154354998 inositol 1,4,5-triphosphate receptor, type 1 isofor... 31 3.8
gi|154354996 inositol 1,4,5-triphosphate receptor, type 1 isofor... 31 3.8
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 31 3.8
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 31 3.8
gi|115298663 SCL/TAL1 interrupting locus isoform 1 [Homo sapiens] 31 3.8
gi|115298661 SCL/TAL1 interrupting locus isoform 2 [Homo sapiens] 31 3.8
gi|217330641 IWS1 homolog [Homo sapiens] 31 3.8
gi|239743053 PREDICTED: hypothetical protein XP_002342748 [Homo ... 30 4.9
gi|55741677 SET domain containing 1A [Homo sapiens] 30 4.9
gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens] 30 4.9
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 30 4.9
>gi|57242805 tyrosyl-DNA phosphodiesterase 1 [Homo sapiens]
Length = 608
Score = 1264 bits (3272), Expect = 0.0
Identities = 608/608 (100%), Positives = 608/608 (100%)
Query: 1 MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKI 60
MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKI
Sbjct: 1 MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKI 60
Query: 61 SPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN 120
SPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN
Sbjct: 61 SPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN 120
Query: 121 DGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNS 180
DGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNS
Sbjct: 121 DGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNS 180
Query: 181 GALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHA 240
GALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHA
Sbjct: 181 GALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHA 240
Query: 241 QAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSP 300
QAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSP
Sbjct: 241 QAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSP 300
Query: 301 LYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPG 360
LYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPG
Sbjct: 301 LYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPG 360
Query: 361 RFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESM 420
RFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESM
Sbjct: 361 RFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESM 420
Query: 421 LTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKW 480
LTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKW
Sbjct: 421 LTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKW 480
Query: 481 SAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELG 540
SAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELG
Sbjct: 481 SAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELG 540
Query: 541 VLFLPSAFGLDSFKVKQKFFAGSQEPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDT 600
VLFLPSAFGLDSFKVKQKFFAGSQEPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDT
Sbjct: 541 VLFLPSAFGLDSFKVKQKFFAGSQEPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDT 600
Query: 601 HGNMWVPS 608
HGNMWVPS
Sbjct: 601 HGNMWVPS 608
>gi|20127586 tyrosyl-DNA phosphodiesterase 1 [Homo sapiens]
Length = 608
Score = 1264 bits (3272), Expect = 0.0
Identities = 608/608 (100%), Positives = 608/608 (100%)
Query: 1 MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKI 60
MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKI
Sbjct: 1 MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKI 60
Query: 61 SPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN 120
SPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN
Sbjct: 61 SPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN 120
Query: 121 DGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNS 180
DGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNS
Sbjct: 121 DGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNS 180
Query: 181 GALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHA 240
GALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHA
Sbjct: 181 GALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHA 240
Query: 241 QAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSP 300
QAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSP
Sbjct: 241 QAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSP 300
Query: 301 LYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPG 360
LYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPG
Sbjct: 301 LYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPG 360
Query: 361 RFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESM 420
RFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESM
Sbjct: 361 RFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESM 420
Query: 421 LTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKW 480
LTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKW
Sbjct: 421 LTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKW 480
Query: 481 SAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELG 540
SAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELG
Sbjct: 481 SAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELG 540
Query: 541 VLFLPSAFGLDSFKVKQKFFAGSQEPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDT 600
VLFLPSAFGLDSFKVKQKFFAGSQEPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDT
Sbjct: 541 VLFLPSAFGLDSFKVKQKFFAGSQEPMATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDT 600
Query: 601 HGNMWVPS 608
HGNMWVPS
Sbjct: 601 HGNMWVPS 608
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/152 (25%), Positives = 63/152 (41%), Gaps = 21/152 (13%)
Query: 13 SSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAA---HKRKISPVKFSNTD 69
S SD E +KP+ L G + E + T + K ++RK+S ++D
Sbjct: 1286 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1345
Query: 70 SVLPPKRQKSGSQEDLGWCLSSSDDELQP--------EMPQKQAEKVVIKKEKDISAPND 121
Q+SG E++ S S+DE +P E+ + Q KK + I D
Sbjct: 1346 F------QESGVSEEV----SESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1395
Query: 122 GTAQRTENHGAPACHRLKEEEDEYETSGEGQD 153
+++ N + +EEE+E E E +D
Sbjct: 1396 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1427
Score = 30.8 bits (68), Expect = 3.8
Identities = 34/151 (22%), Positives = 56/151 (37%), Gaps = 17/151 (11%)
Query: 14 SSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFS------- 66
S D SE++K K C G ++ R CS + + K S
Sbjct: 1035 SCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRI 1094
Query: 67 ------NTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN 120
N S K +SGS SS+D + + +K VI KEK ++
Sbjct: 1095 ELRERRNLSSKRNTKEIQSGSSS--SDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLR 1152
Query: 121 DGTAQRTENHGAPACHRLKEEEDEYETSGEG 151
T ++ + + + + E+D+ + GEG
Sbjct: 1153 TSTKRKQADITSSSSSDI--EDDDQNSIGEG 1181
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/152 (25%), Positives = 63/152 (41%), Gaps = 21/152 (13%)
Query: 13 SSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAA---HKRKISPVKFSNTD 69
S SD E +KP+ L G + E + T + K ++RK+S ++D
Sbjct: 1324 SDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSD 1383
Query: 70 SVLPPKRQKSGSQEDLGWCLSSSDDELQP--------EMPQKQAEKVVIKKEKDISAPND 121
Q+SG E++ S S+DE +P E+ + Q KK + I D
Sbjct: 1384 F------QESGVSEEV----SESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQED 1433
Query: 122 GTAQRTENHGAPACHRLKEEEDEYETSGEGQD 153
+++ N + +EEE+E E E +D
Sbjct: 1434 SSSENKSNSEEEEEEKEEEEEEEEEEEEEEED 1465
Score = 30.8 bits (68), Expect = 3.8
Identities = 34/151 (22%), Positives = 56/151 (37%), Gaps = 17/151 (11%)
Query: 14 SSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFS------- 66
S D SE++K K C G ++ R CS + + K S
Sbjct: 1073 SCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRI 1132
Query: 67 ------NTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN 120
N S K +SGS SS+D + + +K VI KEK ++
Sbjct: 1133 ELRERRNLSSKRNTKEIQSGSSS--SDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLR 1190
Query: 121 DGTAQRTENHGAPACHRLKEEEDEYETSGEG 151
T ++ + + + + E+D+ + GEG
Sbjct: 1191 TSTKRKQADITSSSSSDI--EDDDQNSIGEG 1219
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 37.7 bits (86), Expect = 0.031
Identities = 34/151 (22%), Positives = 60/151 (39%), Gaps = 13/151 (8%)
Query: 10 WTISSSDESEE--EKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSN 67
W + E E E K +P T S+ +EP +EAQ+A + + +
Sbjct: 1897 WEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQP 1956
Query: 68 TDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPN-DGTAQR 126
V+ + + +Q + S + L+ E+ ++AE + +D+ AP +G Q
Sbjct: 1957 ESEVIESQEAEEEAQPE-----SEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQE 2011
Query: 127 TENHGAPACHRLK-----EEEDEYETSGEGQ 152
E P ++ E E+ E GE Q
Sbjct: 2012 AEEEAQPESDGVEAQPKSEGEEAQEVEGETQ 2042
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 35.0 bits (79), Expect = 0.20
Identities = 33/147 (22%), Positives = 58/147 (39%), Gaps = 15/147 (10%)
Query: 13 SSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTD--- 69
S + S+EE D PS+ S + E + E + + +S + N D
Sbjct: 321 SKENLSQEESQNVDGPSSES--------SQEANLSSQENSSESQEEVVSESRGDNPDPTT 372
Query: 70 SVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRTE- 128
S + + S+ED LS S E + E ++ + + E+ +P D + E
Sbjct: 373 SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEG 432
Query: 129 --NHGAPACHRLKEEEDEYETSGEGQD 153
+H + A + +E E E + QD
Sbjct: 433 LQSHSSSAESQSEESHSE-EDDSDSQD 458
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 35.0 bits (79), Expect = 0.20
Identities = 33/147 (22%), Positives = 58/147 (39%), Gaps = 15/147 (10%)
Query: 13 SSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTD--- 69
S + S+EE D PS+ S + E + E + + +S + N D
Sbjct: 305 SKENLSQEESQNVDGPSSES--------SQEANLSSQENSSESQEEVVSESRGDNPDPTT 356
Query: 70 SVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRTE- 128
S + + S+ED LS S E + E ++ + + E+ +P D + E
Sbjct: 357 SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEG 416
Query: 129 --NHGAPACHRLKEEEDEYETSGEGQD 153
+H + A + +E E E + QD
Sbjct: 417 LQSHSSSAESQSEESHSE-EDDSDSQD 442
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 34.7 bits (78), Expect = 0.26
Identities = 34/150 (22%), Positives = 59/150 (39%), Gaps = 13/150 (8%)
Query: 12 ISSSDESEEEKPKPDKPSTSSLLCAR-QGAANEPRYTCSEAQKAAHKRKISPVKFSNTDS 70
+S+S P PS S +L ++ + A + Q +H K +F TDS
Sbjct: 537 LSTSGRRTPGNQTPVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDS 596
Query: 71 VLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRTENH 130
+P + S ED DDE + E + E + E D ++ +D E+
Sbjct: 597 DIPSSKDSEDSNED-----EEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDD 651
Query: 131 GAPACHRLKEEEDEYETSGEGQDIWDMLDK 160
+++DE ++ EG+ L+K
Sbjct: 652 D-------DKDQDESDSDTEGEKTSMKLNK 674
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 33.1 bits (74), Expect = 0.76
Identities = 33/149 (22%), Positives = 55/149 (36%), Gaps = 16/149 (10%)
Query: 17 ESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLPPKR 76
ESE ++ D C + N+ S+ R S + DS KR
Sbjct: 759 ESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKR 818
Query: 77 QKSGSQEDLGWCLSSSDDEL----------------QPEMPQKQAEKVVIKKEKDISAPN 120
Q+S S+ S+ + + + P+ AE+ KKEKD +
Sbjct: 819 QRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEK 878
Query: 121 DGTAQRTENHGAPACHRLKEEEDEYETSG 149
D T QR+E+ + ++ ++TSG
Sbjct: 879 DRTRQRSESKHKSPKKKTGKDSGNWDTSG 907
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 32.7 bits (73), Expect = 1.00
Identities = 36/153 (23%), Positives = 62/153 (40%), Gaps = 28/153 (18%)
Query: 14 SSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLP 73
S SE + K K + +G A SE++ + K+ P S+T++ LP
Sbjct: 887 SESNSERDVTKNSKNDSHPSSDKEEGEATSD----SESEVSEIHIKVKPTTKSSTNTSLP 942
Query: 74 P-------KRQKSGSQEDLGWCLSS-------------SDDELQPEMPQKQAEKVVIKKE 113
+Q++ + + G C +S S + L+ E +K EK+ KK+
Sbjct: 943 DDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKD 1002
Query: 114 KDISAPNDGTAQRTENHGAPACHRLKEEEDEYE 146
K AP ++ H P +EEE+E +
Sbjct: 1003 KKHKAPK----RKQAFHWQPPLEFGEEEEEEID 1031
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 32.0 bits (71), Expect = 1.7
Identities = 19/76 (25%), Positives = 31/76 (40%), Gaps = 8/76 (10%)
Query: 7 YGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKI------ 60
Y W + + D K +PD ++ R G EP T +E +K +R +
Sbjct: 31 YQEWILDTIDSLRSRKARPDLERICRMVRRRHGP--EPERTRAELEKLIQQRAVLRVSYK 88
Query: 61 SPVKFSNTDSVLPPKR 76
+ + N V PP+R
Sbjct: 89 GSISYRNAARVQPPRR 104
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 32.0 bits (71), Expect = 1.7
Identities = 26/120 (21%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 37 RQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDEL 96
RQ E + AQKA + SP + S D+ ++ G QE L + +
Sbjct: 202 RQQEKVERQQEALRAQKATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAF 261
Query: 97 QPEMPQKQAEKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWD 156
P + Q+ ++ +E++ +D E + C + E+E E E +++ D
Sbjct: 262 SPNPEENQSLAPLLVEEEEEKKNDD-----EEEYDQEVCDAKEASEEEEEVEDEEEEVED 316
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 31.6 bits (70), Expect = 2.2
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 18/134 (13%)
Query: 298 LSPLYPRIADGTHKSGESPTHFKADL-ISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIG 356
LSP P ++ TH S ++ K +S + YN + D+ H S
Sbjct: 2484 LSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSES-------- 2535
Query: 357 STPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEF 416
P R ++ W K+ H+SS+P +W G SS+ S ++ S+ SE
Sbjct: 2536 --PSRLPINRSGTW-----KREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSED 2588
Query: 417 KESMLTLG--KESK 428
++ + ++ K+SK
Sbjct: 2589 EKHVNSISGTKQSK 2602
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 31.6 bits (70), Expect = 2.2
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 18/134 (13%)
Query: 298 LSPLYPRIADGTHKSGESPTHFKADL-ISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIG 356
LSP P ++ TH S ++ K +S + YN + D+ H S
Sbjct: 2484 LSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSES-------- 2535
Query: 357 STPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEF 416
P R ++ W K+ H+SS+P +W G SS+ S ++ S+ SE
Sbjct: 2536 --PSRLPINRSGTW-----KREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSED 2588
Query: 417 KESMLTLG--KESK 428
++ + ++ K+SK
Sbjct: 2589 EKHVNSISGTKQSK 2602
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 31.6 bits (70), Expect = 2.2
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 18/134 (13%)
Query: 298 LSPLYPRIADGTHKSGESPTHFKADL-ISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIG 356
LSP P ++ TH S ++ K +S + YN + D+ H S
Sbjct: 2484 LSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSES-------- 2535
Query: 357 STPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEF 416
P R ++ W K+ H+SS+P +W G SS+ S ++ S+ SE
Sbjct: 2536 --PSRLPINRSGTW-----KREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSED 2588
Query: 417 KESMLTLG--KESK 428
++ + ++ K+SK
Sbjct: 2589 EKHVNSISGTKQSK 2602
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 31.6 bits (70), Expect = 2.2
Identities = 27/113 (23%), Positives = 38/113 (33%), Gaps = 4/113 (3%)
Query: 23 PKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQ 82
P P STS + P + RK P S + PP S
Sbjct: 3579 PDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASRKSWPQVVSRASAAKPPSFPPLSSS 3638
Query: 83 EDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRTENHGAPAC 135
+ S S +QP MP + + + D+S +DG A E P+C
Sbjct: 3639 STVT-SSSCSTSGVQPSMPTDDYSE---ESDTDLSQKSDGPASPVEGPKDPSC 3687
>gi|56676330 HP1-BP74 [Homo sapiens]
Length = 553
Score = 31.6 bits (70), Expect = 2.2
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 17 ESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLPPKR 76
E EEEKP+PD S S+ + P T SEA++ + + + K N S K
Sbjct: 59 EGEEEKPEPDISSEESVSTVEEQENETPPATSSEAEQPKGEPE-NEEKEENKSSEETKKD 117
Query: 77 QKSGSQE 83
+K S+E
Sbjct: 118 EKDQSKE 124
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 31.6 bits (70), Expect = 2.2
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 13/157 (8%)
Query: 12 ISSSDESEEEKPKPDKPSTSSLLCARQGAANEP----RYTCSEAQKAAHKRKISPVKFSN 67
+SSS E K +P+K R+ + P R ++A+ + S + ++
Sbjct: 117 LSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNS 176
Query: 68 TDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRT 127
+ + SGS ++ G + ++ ++ ++ ++ E+V E+D DG +
Sbjct: 177 EEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV--EEDEEVEEDAEEDEEVDEDGEEEEE 234
Query: 128 ENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPF 164
E +EEE+EYE QD D ++GN +
Sbjct: 235 EEEEEE--EEEEEEEEEYE-----QDERDQKEEGNDY 264
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 31.6 bits (70), Expect = 2.2
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 13/157 (8%)
Query: 12 ISSSDESEEEKPKPDKPSTSSLLCARQGAANEP----RYTCSEAQKAAHKRKISPVKFSN 67
+SSS E K +P+K R+ + P R ++A+ + S + ++
Sbjct: 117 LSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNS 176
Query: 68 TDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRT 127
+ + SGS ++ G + ++ ++ ++ ++ E+V E+D DG +
Sbjct: 177 EEYGSDHETGSSGSSDEQGNNTENEEEGVEEDV--EEDEEVEEDAEEDEEVDEDGEEEEE 234
Query: 128 ENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPF 164
E +EEE+EYE QD D ++GN +
Sbjct: 235 EEEEEE--EEEEEEEEEYE-----QDERDQKEEGNDY 264
>gi|154354998 inositol 1,4,5-triphosphate receptor, type 1 isoform 1
[Homo sapiens]
Length = 2710
Score = 30.8 bits (68), Expect = 3.8
Identities = 25/102 (24%), Positives = 43/102 (42%)
Query: 49 SEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKV 108
S QK A ++S + DSVL R E L +S+ +D L+P + + + V
Sbjct: 1568 SIVQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLV 1627
Query: 109 VIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYETSGE 150
+ ++ P + A+R G C +K + E + E
Sbjct: 1628 DVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEE 1669
>gi|154354996 inositol 1,4,5-triphosphate receptor, type 1 isoform 2
[Homo sapiens]
Length = 2695
Score = 30.8 bits (68), Expect = 3.8
Identities = 25/102 (24%), Positives = 43/102 (42%)
Query: 49 SEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKV 108
S QK A ++S + DSVL R E L +S+ +D L+P + + + V
Sbjct: 1553 SIVQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLV 1612
Query: 109 VIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYETSGE 150
+ ++ P + A+R G C +K + E + E
Sbjct: 1613 DVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEE 1654
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 30.8 bits (68), Expect = 3.8
Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 13/102 (12%)
Query: 58 RKISPVKFSNTDSVLPPKRQKSGS----QEDLGWCLSSSD------DELQ--PEMPQKQA 105
RK+ V F TD +L K +K Q D W + +D DEL+ P +P
Sbjct: 723 RKLRHV-FLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPD 781
Query: 106 EKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYET 147
E++ K K ND ++ N G+ A RLK++ E E+
Sbjct: 782 EELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQES 823
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 30.8 bits (68), Expect = 3.8
Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 13/102 (12%)
Query: 58 RKISPVKFSNTDSVLPPKRQKSGS----QEDLGWCLSSSD------DELQ--PEMPQKQA 105
RK+ V F TD +L K +K Q D W + +D DEL+ P +P
Sbjct: 723 RKLRHV-FLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLTDLSFQMVDELEAVPNIPLVPD 781
Query: 106 EKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYET 147
E++ K K ND ++ N G+ A RLK++ E E+
Sbjct: 782 EELDALKIKISQIKNDIQREKRANKGSKATERLKKKLSEQES 823
>gi|115298663 SCL/TAL1 interrupting locus isoform 1 [Homo sapiens]
Length = 1288
Score = 30.8 bits (68), Expect = 3.8
Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 12 ISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSV 71
+ SSD SE+E+ PD + S Q + P + + + + +I + SN +SV
Sbjct: 1130 LQSSDNSEDEEEPPDNADSKSEYLLNQNLRSIPEQLGGQKEPSKNDHEI--INCSNCESV 1187
Query: 72 LPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEK--VVIKKEKDISAPN--DGTAQRT 127
G+ D + +++ LQ + Q+ EK ++K K A N G A+ T
Sbjct: 1188 --------GTNADTPVLRNITNEVLQTKAKQQLTEKPAFLVKNLKPSPAVNLRTGKAEFT 1239
Query: 128 EN 129
++
Sbjct: 1240 QH 1241
>gi|115298661 SCL/TAL1 interrupting locus isoform 2 [Homo sapiens]
Length = 1287
Score = 30.8 bits (68), Expect = 3.8
Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 14/122 (11%)
Query: 12 ISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSV 71
+ SSD SE+E+ PD + S Q + P + + + + +I + SN +SV
Sbjct: 1129 LQSSDNSEDEEEPPDNADSKSEYLLNQNLRSIPEQLGGQKEPSKNDHEI--INCSNCESV 1186
Query: 72 LPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEK--VVIKKEKDISAPN--DGTAQRT 127
G+ D + +++ LQ + Q+ EK ++K K A N G A+ T
Sbjct: 1187 --------GTNADTPVLRNITNEVLQTKAKQQLTEKPAFLVKNLKPSPAVNLRTGKAEFT 1238
Query: 128 EN 129
++
Sbjct: 1239 QH 1240
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 30.8 bits (68), Expect = 3.8
Identities = 33/139 (23%), Positives = 57/139 (41%), Gaps = 11/139 (7%)
Query: 14 SSDESEEEKPKPDKPSTSSLLCARQGAANEP----RYTCSEAQKAAHKRKISPVKFSNTD 69
S ESEE + P S + L + +E ++ S+++ + + SP S T+
Sbjct: 118 SDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSE--IEELQKSPASDSETE 175
Query: 70 SVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKK----EKDISAPNDGTAQ 125
L P+ S S+E S S++E P+ +E + K + + P A
Sbjct: 176 DALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQAS 235
Query: 126 RTENHGAPACHRLKEEEDE 144
+EN P R+ + E E
Sbjct: 236 DSENEELPK-PRISDSESE 253
>gi|239743053 PREDICTED: hypothetical protein XP_002342748 [Homo
sapiens]
Length = 591
Score = 30.4 bits (67), Expect = 4.9
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 403 SLGADESKWLCSEFKESMLTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGG 458
SL ES+W+C S+ T +P +++ P +LI S+ +R L G PA G
Sbjct: 69 SLDVSESRWICEIHCWSLRT------SPKQAAAPDWLIAGSLFPLRVVLPGIPAPG 118
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 30.4 bits (67), Expect = 4.9
Identities = 32/142 (22%), Positives = 58/142 (40%), Gaps = 15/142 (10%)
Query: 15 SDESEEEKPKPDKPSTSSLLCARQ-GAANEPRYTCSEAQKAAHKRKISPVKFSNT---DS 70
S+ SEE++P+P P+ Q A EP ++ K +R + K + DS
Sbjct: 904 SEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDS 963
Query: 71 VLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRTENH 130
Q+S S++D DDE E ++ KKE ++S D E+
Sbjct: 964 EGEEASQESSSEKD------EEDDEEDEEDEDREEAVDTTKKETEVSDGED-----EESD 1012
Query: 131 GAPACHRLKEEEDEYETSGEGQ 152
+ C + + E +++ + +
Sbjct: 1013 SSSKCSLYADSDGENDSTSDSE 1034
>gi|151101407 prothymosin, alpha isoform 1 [Homo sapiens]
Length = 111
Score = 30.4 bits (67), Expect = 4.9
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 6/57 (10%)
Query: 103 KQAEKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKE------EEDEYETSGEGQD 153
K+ ++VV + E AP +G A+ EN A + + E EE+E E G+G++
Sbjct: 18 KEKKEVVEEAENGRDAPANGNAENEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEE 74
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 30.4 bits (67), Expect = 4.9
Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 1/79 (1%)
Query: 19 EEEKPKPDKPSTSSLLCAR-QGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLPPKRQ 77
++++P+ PST S A Q + + + T Q+ +++S F + S P
Sbjct: 561 QQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTS 620
Query: 78 KSGSQEDLGWCLSSSDDEL 96
G QED+ L S L
Sbjct: 621 SKGGQEDMNLSLQSRPSSL 639
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,644,239
Number of Sequences: 37866
Number of extensions: 1290847
Number of successful extensions: 2860
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 2829
Number of HSP's gapped (non-prelim): 61
length of query: 608
length of database: 18,247,518
effective HSP length: 108
effective length of query: 500
effective length of database: 14,157,990
effective search space: 7078995000
effective search space used: 7078995000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.