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Search of human proteins with 56790930
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56790930 echinoderm microtubule associated protein like 1
isoform b [Homo sapiens]
(815 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56790930 echinoderm microtubule associated protein like 1 iso... 1671 0.0
gi|56790932 echinoderm microtubule associated protein like 1 iso... 1660 0.0
gi|6912356 echinoderm microtubule associated protein like 2 [Hom... 981 0.0
gi|223029510 echinoderm microtubule associated protein like 4 is... 938 0.0
gi|19923497 echinoderm microtubule associated protein like 4 iso... 920 0.0
gi|110227615 echinoderm microtubule associated protein like 3 [H... 774 0.0
gi|223005862 echinoderm microtubule associated protein like 6 [H... 394 e-109
gi|34485720 echinoderm microtubule associated protein like 5 [Ho... 382 e-106
gi|31377846 WD repeat domain 52 [Homo sapiens] 85 2e-16
gi|94400919 WD repeat domain 90 [Homo sapiens] 74 7e-13
gi|190684677 mitogen-activated protein kinase binding protein 1 ... 72 3e-12
gi|21071067 TBP-associated factor 5 [Homo sapiens] 71 4e-12
gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens] 70 6e-12
gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens] 70 6e-12
gi|190684671 mitogen-activated protein kinase binding protein 1 ... 63 1e-09
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 62 2e-09
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 62 2e-09
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 62 2e-09
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 62 2e-09
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 62 2e-09
gi|32189425 WD repeat domain 69 [Homo sapiens] 61 5e-09
gi|124028512 WD40-repeat protein upregulated in HCC isoform b [H... 60 1e-08
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 57 9e-08
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 57 9e-08
gi|26665869 WD repeat domain 51B [Homo sapiens] 56 1e-07
gi|145279222 WD repeat domain 66 [Homo sapiens] 56 2e-07
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 54 6e-07
gi|16554629 WD repeat domain 5 [Homo sapiens] 54 8e-07
gi|16554627 WD repeat domain 5 [Homo sapiens] 54 8e-07
gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens] 54 8e-07
>gi|56790930 echinoderm microtubule associated protein like 1
isoform b [Homo sapiens]
Length = 815
Score = 1671 bits (4328), Expect = 0.0
Identities = 815/815 (100%), Positives = 815/815 (100%)
Query: 1 MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALA 60
MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALA
Sbjct: 1 MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALA 60
Query: 61 DVVRRLNITEEQQAVLNRKGPTKARPLMQTLPLRTTVNNGTVLPKKPTGSLPSPSGVRKE 120
DVVRRLNITEEQQAVLNRKGPTKARPLMQTLPLRTTVNNGTVLPKKPTGSLPSPSGVRKE
Sbjct: 61 DVVRRLNITEEQQAVLNRKGPTKARPLMQTLPLRTTVNNGTVLPKKPTGSLPSPSGVRKE 120
Query: 121 TAVPATKSNIKRTSSSERVSPGGRRESNGDSRGNRNRTGSTSSSSSGKKNSESKPKEPVF 180
TAVPATKSNIKRTSSSERVSPGGRRESNGDSRGNRNRTGSTSSSSSGKKNSESKPKEPVF
Sbjct: 121 TAVPATKSNIKRTSSSERVSPGGRRESNGDSRGNRNRTGSTSSSSSGKKNSESKPKEPVF 180
Query: 181 SAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDCRNNLYL 240
SAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDCRNNLYL
Sbjct: 181 SAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDCRNNLYL 240
Query: 241 LPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQ 300
LPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQ
Sbjct: 241 LPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQ 300
Query: 301 LPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQK 360
LPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQK
Sbjct: 301 LPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQK 360
Query: 361 EEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKF 420
EEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKF
Sbjct: 361 EEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKF 420
Query: 421 VLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGK 480
VLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGK
Sbjct: 421 VLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGK 480
Query: 481 DRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQ 540
DRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQ
Sbjct: 481 DRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQ 540
Query: 541 GHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVA 600
GHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVA
Sbjct: 541 GHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVA 600
Query: 601 VGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGR 660
VGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGR
Sbjct: 601 VGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGR 660
Query: 661 KYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWAT 720
KYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWAT
Sbjct: 661 KYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWAT 720
Query: 721 YTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIY 780
YTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIY
Sbjct: 721 YTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIY 780
Query: 781 GGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI 815
GGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI
Sbjct: 781 GGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI 815
>gi|56790932 echinoderm microtubule associated protein like 1
isoform a [Homo sapiens]
Length = 834
Score = 1660 bits (4298), Expect = 0.0
Identities = 815/834 (97%), Positives = 815/834 (97%), Gaps = 19/834 (2%)
Query: 1 MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALA 60
MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALA
Sbjct: 1 MEDGFSSYSSLYDTSSLLQFCNDDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALA 60
Query: 61 DVVRRLNITEEQQAVLNRKGPTKARPLMQTLPLRTTVNNGTVLPKKPTGSLPSPSGVRKE 120
DVVRRLNITEEQQAVLNRKGPTKARPLMQTLPLRTTVNNGTVLPKKPTGSLPSPSGVRKE
Sbjct: 61 DVVRRLNITEEQQAVLNRKGPTKARPLMQTLPLRTTVNNGTVLPKKPTGSLPSPSGVRKE 120
Query: 121 TAVPATK-------------------SNIKRTSSSERVSPGGRRESNGDSRGNRNRTGST 161
TAVPATK SNIKRTSSSERVSPGGRRESNGDSRGNRNRTGST
Sbjct: 121 TAVPATKRLNRSVSLLNACKLNRSTPSNIKRTSSSERVSPGGRRESNGDSRGNRNRTGST 180
Query: 162 SSSSSGKKNSESKPKEPVFSAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRL 221
SSSSSGKKNSESKPKEPVFSAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRL
Sbjct: 181 SSSSSGKKNSESKPKEPVFSAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRL 240
Query: 222 KLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHP 281
KLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHP
Sbjct: 241 KLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHP 300
Query: 282 DRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTN 341
DRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTN
Sbjct: 301 DRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTN 360
Query: 342 LCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLE 401
LCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLE
Sbjct: 361 LCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLE 420
Query: 402 GSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEG 461
GSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEG
Sbjct: 421 GSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEG 480
Query: 462 GIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGT 521
GIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGT
Sbjct: 481 GIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGT 540
Query: 522 TRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDK 581
TRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDK
Sbjct: 541 TRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDK 600
Query: 582 IIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFL 641
IIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFL
Sbjct: 601 IIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFL 660
Query: 642 AIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVP 701
AIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVP
Sbjct: 661 AIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVP 720
Query: 702 SACKQVVSVETTRDIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFG 761
SACKQVVSVETTRDIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFG
Sbjct: 721 SACKQVVSVETTRDIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFG 780
Query: 762 KVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI 815
KVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI
Sbjct: 781 KVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI 834
>gi|6912356 echinoderm microtubule associated protein like 2 [Homo
sapiens]
Length = 649
Score = 981 bits (2537), Expect = 0.0
Identities = 440/642 (68%), Positives = 534/642 (83%)
Query: 174 KPKEPVFSAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRD 233
K KE +FS E+G VKMFLRGRPV M +P + +YSL+ + ELP+ RLKLEWVYGYRGRD
Sbjct: 8 KTKEVIFSVEDGSVKMFLRGRPVPMMIPDELAPTYSLDTRSELPSCRLKLEWVYGYRGRD 67
Query: 234 CRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAG 293
CR NLYLLPTGE VYF+ASV VLY+VEEQ QRHY GHNDD+KCLA+HPD +TIATGQVAG
Sbjct: 68 CRANLYLLPTGEIVYFVASVAVLYSVEEQRQRHYLGHNDDIKCLAIHPDMVTIATGQVAG 127
Query: 294 TSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVL 353
T+K+GK LPPHVRIWDSV+L+TLHV+G+G FDRAV C+ FSKSNGG LCAVD+SNDH+L
Sbjct: 128 TTKEGKPLPPHVRIWDSVSLSTLHVLGLGVFDRAVCCVGFSKSNGGNLLCAVDESNDHML 187
Query: 354 SVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFE 413
SVWDW KE K+ DVKCSNEAV A FHPTD +++TCGKSH+YFWTLEG SL+K+QGLFE
Sbjct: 188 SVWDWAKETKVVDVKCSNEAVLVATFHPTDPTVLITCGKSHIYFWTLEGGSLSKRQGLFE 247
Query: 414 KQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGT 473
K EKPK+VLCVTF E GD +TGDS GN+ VWGKG NRI+ AV GAH+GG+F LC LRDGT
Sbjct: 248 KHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNRITQAVLGAHDGGVFGLCALRDGT 307
Query: 474 LVSGGGKDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSG 533
LVSGGG+DR+++ W +Y KL++ E+PE FGP+RTVAEG GD + +GTTRN +LQG++
Sbjct: 308 LVSGGGRDRRVVLWGSDYSKLQEVEVPEDFGPVRTVAEGHGDTLYVGTTRNSILQGSVHT 367
Query: 534 DFTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFH 593
F+ + QGH +ELWGLA H S++QF+TCG DK LW + H+P+W +IIEDPA+S+GFH
Sbjct: 368 GFSLLVQGHVEELWGLATHPSRAQFVTCGQDKLVHLWSSDSHQPLWSRIIEDPARSAGFH 427
Query: 594 PSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIY 653
PSGSV+AVGT+TGRW + DTET DLV +HTDGNEQ+SV+ +SPDG +LA+GSHDN +Y+Y
Sbjct: 428 PSGSVLAVGTVTGRWLLLDTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVY 487
Query: 654 GVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETT 713
V GRK +R+GKCSGHSSFITHLDW+ +S V+NSGDYEILYW P+ CKQ+ S +
Sbjct: 488 TVDQGGRKVSRLGKCSGHSSFITHLDWAQDSSCFVTNSGDYEILYWDPATCKQITSADAV 547
Query: 714 RDIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQF 773
R++EWAT TC LGF VFG+W EG+DGTDINAV R+H+ KLL++ DDFGKVHLFSYPC Q
Sbjct: 548 RNMEWATATCVLGFGVFGIWSEGADGTDINAVARSHDGKLLASADDFGKVHLFSYPCCQP 607
Query: 774 RAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI 815
RA SH YGGHSSHVTNV FL +DS ++TGGKDTS++QWRV+
Sbjct: 608 RALSHKYGGHSSHVTNVAFLWDDSMALTTGGKDTSVLQWRVV 649
>gi|223029510 echinoderm microtubule associated protein like 4
isoform b [Homo sapiens]
Length = 923
Score = 938 bits (2424), Expect = 0.0
Identities = 445/806 (55%), Positives = 592/806 (73%), Gaps = 20/806 (2%)
Query: 23 DDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPT 82
DDS SAAS+ +V DR+++LE RVQ QED+I +LK+ALADV+RRL I+E+ A + + +
Sbjct: 9 DDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSS 68
Query: 83 KARPLMQTLPLRTTVNNGTVLPKKPTGSLPSPSGVRKETAVPATKSNIKRTSSSERVSPG 142
K +P + + + + NG+ +KP+ + + S KET A KS IKR S +E+
Sbjct: 69 KGQPSPRAVIPMSCITNGSGANRKPSHT-SAVSIAGKETLSSAAKS-IKRPSPAEKSHNS 126
Query: 143 GRRESNGDSRGNRNRTGSTSSSSSGKKNSESKPKEPVFSAEEGYVKMFLRGRPVTMYMPK 202
E++ DSR ++ ST + K K+ + + E Y+KMF+RGRP+TM++P
Sbjct: 127 W--ENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQEGEYIKMFMRGRPITMFIPS 184
Query: 203 DQVDSYSLEAKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQ 262
D VD+Y + + ELP ++LKLEW YGYRG+DCR N+YLLPTGE VYFIASVVVL+N EE+
Sbjct: 185 D-VDNYD-DIRTELPPEKLKLEWAYGYRGKDCRANVYLLPTGEIVYFIASVVVLFNYEER 242
Query: 263 LQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIG 322
QRHY GH D VKCLA+HPD+I IATGQ+AG KDG+ L PHVR+WDSVTL+TL +IG+G
Sbjct: 243 TQRHYLGHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLG 302
Query: 323 FFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPT 382
F+R V C+ FSK++ G +LC +DDSN+H+L+VWDWQK+ K A++K +NE V A +FHPT
Sbjct: 303 TFERGVGCLDFSKADSGVHLCVIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPT 362
Query: 383 DTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNIL 442
D N I+TCGKSH++FWT G+SL +KQG+F K EKPKFV C+ F NGD +TGDS G +L
Sbjct: 363 DANTIITCGKSHIFFWTWSGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVML 422
Query: 443 VWG------------KGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGN 490
+W KG +IS ++ AH+G +F LC +R+G L++GGGKDRK+I W +
Sbjct: 423 IWSKTTVEPTPGKGPKGVYQISKQIK-AHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHD 481
Query: 491 YQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQGHTDELWGLA 550
R+ E+P+Q+G IR VAEGK D L+GT+RNF+L+GT + F QGHTDELWGLA
Sbjct: 482 LNPEREIEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGTFNDGFQIEVQGHTDELWGLA 541
Query: 551 IHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFV 610
H K LTC D+ LW+++ HR W +++++P + FHPSG+VVA+GT +GRWFV
Sbjct: 542 THPFKDLLLTCAQDRQVCLWNSMEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFV 601
Query: 611 FDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSG 670
D ET+DLV++HTDGNEQLSVMRYS DG FLA+GSHDN IY+Y VS+NGRKY+R G+C+G
Sbjct: 602 LDAETRDLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKYSRYGRCTG 661
Query: 671 HSSFITHLDWSVNSQFLVSNSGDYEILYW-VPSACKQVVSVETTRDIEWATYTCTLGFHV 729
HSS+ITHLDWS ++++++SNSGDYEILYW +P+ CK + + +DI+W TYTC LGF V
Sbjct: 662 HSSYITHLDWSPDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTYTCVLGFQV 721
Query: 730 FGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTN 789
FGVWPEGSDGTDINA+ R+H +K+++ DDF KVHLF YPCS+ +APSH Y HSSHVTN
Sbjct: 722 FGVWPEGSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTN 781
Query: 790 VDFLCEDSHLISTGGKDTSIMQWRVI 815
V F DSHLISTGGKD SI+QW+++
Sbjct: 782 VSFTHNDSHLISTGGKDMSIIQWKLV 807
>gi|19923497 echinoderm microtubule associated protein like 4
isoform a [Homo sapiens]
Length = 981
Score = 920 bits (2379), Expect = 0.0
Identities = 445/860 (51%), Positives = 590/860 (68%), Gaps = 70/860 (8%)
Query: 23 DDSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAVLNRKGPT 82
DDS SAAS+ +V DR+++LE RVQ QED+I +LK+ALADV+RRL I+E+ A + + +
Sbjct: 9 DDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSS 68
Query: 83 KARPLMQTLPLRTTVNNGTVLPKKP------------TGSLPSPSGVRKETAVPATKSNI 130
K +P + + + + NG+ +KP T S + SG K+ P +
Sbjct: 69 KGQPSPRAVIPMSCITNGSGANRKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREK 128
Query: 131 KRTSSSERVSPGGRR------------------------------------------ESN 148
K S S SP R E++
Sbjct: 129 KEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEKSHNSWENS 188
Query: 149 GDSRGNRNRTGSTSSSSSGKKNSESKPKEPVFSAEEGYVKMFLRGRPVTMYMPKDQVDSY 208
DSR ++ ST + K K+ + + E Y+KMF+RGRP+TM++P D VD+Y
Sbjct: 189 DDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQEGEYIKMFMRGRPITMFIPSD-VDNY 247
Query: 209 SLEAKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYA 268
+ + ELP ++LKLEW YGYRG+DCR N+YLLPTGE VYFIASVVVL+N EE+ QRHY
Sbjct: 248 D-DIRTELPPEKLKLEWAYGYRGKDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYL 306
Query: 269 GHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAV 328
GH D VKCLA+HPD+I IATGQ+AG KDG+ L PHVR+WDSVTL+TL +IG+G F+R V
Sbjct: 307 GHTDCVKCLAIHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVTLSTLQIIGLGTFERGV 366
Query: 329 TCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIV 388
C+ FSK++ G +LC +DDSN+H+L+VWDWQK+ K A++K +NE V A +FHPTD N I+
Sbjct: 367 GCLDFSKADSGVHLCVIDDSNEHMLTVWDWQKKAKGAEIKTTNEVVLAVEFHPTDANTII 426
Query: 389 TCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWG--- 445
TCGKSH++FWT G+SL +KQG+F K EKPKFV C+ F NGD +TGDS G +L+W
Sbjct: 427 TCGKSHIFFWTWSGNSLTRKQGIFGKYEKPKFVQCLAFLGNGDVLTGDSGGVMLIWSKTT 486
Query: 446 ---------KGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRK 496
KG +IS ++ AH+G +F LC +R+G L++GGGKDRK+I W + R+
Sbjct: 487 VEPTPGKGPKGVYQISKQIK-AHDGSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPERE 545
Query: 497 TEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKS 556
E+P+Q+G IR VAEGK D L+GT+RNF+L+GT + F QGHTDELWGLA H K
Sbjct: 546 IEVPDQYGTIRAVAEGKADQFLVGTSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKD 605
Query: 557 QFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETK 616
LTC D+ LW+++ HR W +++++P + FHPSG+VVA+GT +GRWFV D ET+
Sbjct: 606 LLLTCAQDRQVCLWNSMEHRLEWTRLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETR 665
Query: 617 DLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFIT 676
DLV++HTDGNEQLSVMRYS DG FLA+GSHDN IY+Y VS+NGRKY+R G+C+GHSS+IT
Sbjct: 666 DLVSIHTDGNEQLSVMRYSIDGTFLAVGSHDNFIYLYVVSENGRKYSRYGRCTGHSSYIT 725
Query: 677 HLDWSVNSQFLVSNSGDYEILYW-VPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPE 735
HLDWS ++++++SNSGDYEILYW +P+ CK + + +DI+W TYTC LGF VFGVWPE
Sbjct: 726 HLDWSPDNKYIMSNSGDYEILYWDIPNGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPE 785
Query: 736 GSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCE 795
GSDGTDINA+ R+H +K+++ DDF KVHLF YPCS+ +APSH Y HSSHVTNV F
Sbjct: 786 GSDGTDINALVRSHNRKVIAVADDFCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHN 845
Query: 796 DSHLISTGGKDTSIMQWRVI 815
DSHLISTGGKD SI+QW+++
Sbjct: 846 DSHLISTGGKDMSIIQWKLV 865
>gi|110227615 echinoderm microtubule associated protein like 3 [Homo
sapiens]
Length = 896
Score = 774 bits (1999), Expect = 0.0
Identities = 405/878 (46%), Positives = 543/878 (61%), Gaps = 95/878 (10%)
Query: 24 DSASAASSMEVTDRIASLEQRVQMQEDDIQLLKSALADVVRRLNITEEQQAV-------- 75
D A+ + + SL QR+++QE +++L+K+ALA+ +R L + ++
Sbjct: 2 DGAAGPGDGPAREALQSLSQRLRVQEQEMELVKAALAEALRLLRLQVPPSSLQGSGTPAP 61
Query: 76 -------------------LNRKGPTKARPLMQTLPLRTTVNNGTVLPKKPTGSLPSPSG 116
++R T+ +++ P ++NG P P G+ PSG
Sbjct: 62 PGDSLAAPPGLPPTCTPSLVSRGTQTETEVELKSSPGPPGLSNG---PPAPQGASEEPSG 118
Query: 117 VRKE--------TAVPATKSNIKRTSSSERVSPGGRRESNGDSRGNRNR----------- 157
+ E P ++ +R R S+ S R R
Sbjct: 119 TQSEGGGSSSSGAGSPGPPGILRPLQPPQRADTPRRNSSSSSSPSERPRQKLSRKAISSA 178
Query: 158 ---TGSTSSSSSGKKNSESKPKEPV-----FSAEEGYVKMFLRGRPVTMYMPKDQVDSYS 209
S S+ S G K+ S P P ++ E VKMFLRGRP+TMY+P
Sbjct: 179 NLLVRSGSTESRGGKDPLSSPGGPGSRRSNYNLEGISVKMFLRGRPITMYIPS------G 232
Query: 210 LEAKVELPT----KRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQL-- 263
+ + ELP+ + L L+WVYGYRGRD R+NL++L +GE VYFIA VVVLY
Sbjct: 233 IRSLEELPSGPPPETLSLDWVYGYRGRDSRSNLFVLRSGEVVYFIACVVVLYRPGGGPGG 292
Query: 264 -----QRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHV 318
QRHY GH D V+CLAVHPD + +A+GQ AG KDGK L P V IWDS TL L
Sbjct: 293 PGGGGQRHYRGHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSETLLKLQE 352
Query: 319 IGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAAD 378
IG+G F+R V +AFS ++ G LC VDDSN+H+LSVWD + KLA++K +N++V A
Sbjct: 353 IGLGAFERGVGALAFSAADQGAFLCVVDDSNEHMLSVWDCSRGMKLAEIKSTNDSVLAVG 412
Query: 379 FHPTDTNIIVTCGKSHLYFWTLEGS-------SLNKKQGLFEKQEKPKFVLCVTFSENGD 431
F+P D++ IVT GKSH++FW G +L +KQG+F K +KPKF+ C F +GD
Sbjct: 413 FNPRDSSCIVTSGKSHVHFWNWSGGVGVPGNGTLTRKQGVFGKYKKPKFIPCFVFLPDGD 472
Query: 432 TITGDSSGNILVWGK----------GTNRISYAVQG---AHEGGIFALCMLRDGTLVSGG 478
+TGDS GNIL WG+ G + +Y + AHEG IFALC+ RDGT++SGG
Sbjct: 473 ILTGDSEGNILTWGRSPSDSKTPGRGGAKETYGIVAQAHAHEGSIFALCLRRDGTVLSGG 532
Query: 479 GKDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPI 538
G+DR+L+ W L++ EIPE FG +R +AEG G +L+GTT+N +L+G L+ F+P+
Sbjct: 533 GRDRRLVQWGPGLVALQEAEIPEHFGAVRAIAEGLGSELLVGTTKNALLRGDLAQGFSPV 592
Query: 539 TQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGSV 598
QGHTDELWGL H S+++FLTCGHD+ LWD H W +++ + FHPSG+V
Sbjct: 593 IQGHTDELWGLCTHPSQNRFLTCGHDRQLCLWDGESHALAWSIDLKETGLCADFHPSGAV 652
Query: 599 VAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDN 658
VAVG TGRW V DTET+++V+ DGNEQLSV+RYSPDG +LAIGSHDN IYIY VS +
Sbjct: 653 VAVGLNTGRWLVLDTETREIVSDVIDGNEQLSVVRYSPDGLYLAIGSHDNVIYIYSVSSD 712
Query: 659 GRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW-VPSACKQVVSVETTRDIE 717
G K +R G+C GHSSFITHLDWS + F++SNSGDYEILYW V CKQ+ + +RD E
Sbjct: 713 GAKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDYEILYWDVAGGCKQLKNRYESRDRE 772
Query: 718 WATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPS 777
WATYTC LGFHV+GVWP+GSDGTDIN++CR+H +++++ DDF KVHLF YPC++ +APS
Sbjct: 773 WATYTCVLGFHVYGVWPDGSDGTDINSLCRSHNERVVAVADDFCKVHLFQYPCARAKAPS 832
Query: 778 HIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI 815
+YGGH SHVT+V F +DSHL+S GGKD SI QWRV+
Sbjct: 833 RMYGGHGSHVTSVRFTHDDSHLVSLGGKDASIFQWRVL 870
>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
sapiens]
Length = 1958
Score = 394 bits (1013), Expect = e-109
Identities = 225/607 (37%), Positives = 342/607 (56%), Gaps = 27/607 (4%)
Query: 217 PTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKC 276
P +L+LEWVYGYRG CRNNLY E VYF+A V V+YN E Q+ + GHNDD+
Sbjct: 7 PRCQLRLEWVYGYRGHQCRNNLYYTAGKEVVYFVAGVGVVYNTREHSQKFFLGHNDDIIS 66
Query: 277 LAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKS 336
LA+HPD+ +ATGQV GK+ P++ IWDS + T+ ++ V C+AF
Sbjct: 67 LALHPDKTLVATGQV------GKE--PYICIWDSYNVQTVSLLK-DVHTHGVACLAFDSD 117
Query: 337 NGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLY 396
G L +V + + +WDW+K + LA ++ +F + P N +V+CG H+
Sbjct: 118 --GQRLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDPYQPNRVVSCGVKHIK 175
Query: 397 FWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQ 456
FWTL G++L K+G+F K + +LC+ ++ T +G +G+I VW KG N + +Q
Sbjct: 176 FWTLCGNALTAKRGIFGKTGDLQTILCLACAKEDITYSGALNGDIYVW-KGLNLVR-TIQ 233
Query: 457 GAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQK-----LRKTEIPEQFGPIRTVAE 511
GAH GIF++ +G + GG+D + W +++ LR+TE + IR+V
Sbjct: 234 GAHSAGIFSMYACEEG--FATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVC- 290
Query: 512 GKGDVILIGTTRNFVLQGTLSGDFTP--ITQGHTD-ELWGLAIHASKSQFLTCGHDKHAT 568
K D +L GT + + + + P I QGH + ELW LA+H K +T D+
Sbjct: 291 WKADRLLAGTQDSEIFEVIVRERDKPMLILQGHCEGELWALALHPKKPLAVTGSDDRSVR 350
Query: 569 LWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQ 628
LW H + +E+ +S F P GS +A+G G + V V D E
Sbjct: 351 LWSLADHALIARCNMEEAVRSVAFSPDGSQLALGMKDGSFIVLRVRDMTEVVHIKDRKEV 410
Query: 629 LSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLV 688
+ M++SPDG++LA+GS+D + +Y V+ ++Y ++G+CS SFITH+DWS++S++L
Sbjct: 411 IHEMKFSPDGSYLAVGSNDGPVDVYAVA---QRYKKIGECSKSLSFITHIDWSLDSKYLQ 467
Query: 689 SNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRA 748
+N G E L++ + K + S E + I WA++TC G V G+WP+ ++ TDIN+V
Sbjct: 468 TNDGAGERLFYRMPSGKPLTSKEEIKGIPWASWTCVKGPEVSGIWPKYTEVTDINSVDAN 527
Query: 749 HEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTS 808
+ +L +GDDFG V LF +PC + A Y GHS+HVTNV + + ++STGG D S
Sbjct: 528 YNSSVLVSGDDFGLVKLFKFPCLKRGAKFRKYVGHSAHVTNVRWSHDFQWVLSTGGADHS 587
Query: 809 IMQWRVI 815
+ QWR I
Sbjct: 588 VFQWRFI 594
Score = 354 bits (908), Expect = 2e-97
Identities = 231/690 (33%), Positives = 347/690 (50%), Gaps = 46/690 (6%)
Query: 147 SNGDSRGNRNRTGSTSSSSSGKKNSESKPKEPVFSAEEGYV----KMFLRGRPVTMYMPK 202
SNG G+ S S + P+ +E + +++ P K
Sbjct: 599 SNGMLETAPQEGGADSYSEESDSDLSDVPELDSDIEQEAQINYDRQVYKEDLPQLKQQSK 658
Query: 203 DQVDSYSLEAKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQ 262
++ + + + P LKL++++GYRG DCRNNL+ GE VY IA+V V+YN ++
Sbjct: 659 EKNHAVPFLKREKAPEDSLKLQFIHGYRGYDCRNNLFYTQAGEVVYHIAAVAVVYNRQQH 718
Query: 263 LQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIG 322
QR Y GH+DD+ L +HP + +ATGQV G+ HV WD+ TL L ++ G
Sbjct: 719 SQRLYLGHDDDILSLTIHPVKDYVATGQV------GRDAAIHV--WDTQTLKCLSLLK-G 769
Query: 323 FFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPT 382
R V + FS G L +V + H + WDW+K EK+A + + +F +P
Sbjct: 770 QHQRGVCALDFSAD--GKCLVSVGLDDFHSIVFWDWKKGEKIATTRGHKDKIFVVKCNPH 827
Query: 383 DTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSGNI 441
+ +VT G H+ FW G K+G F K + ++CV++ D + +G ++G+I
Sbjct: 828 HVDKLVTVGIKHIKFWQQAGGGFTSKRGTFGSVGKLETMMCVSYGRMEDLVFSGAATGDI 887
Query: 442 LVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTE--- 498
+W + + AH+G +FA+ L G + GGKD + W +++ KT
Sbjct: 888 FIW---KDILLLKTVKAHDGPVFAMYALDKGFVT--GGKDGIVELWDDMFERCLKTYAIK 942
Query: 499 -----------IPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQGHTD-EL 546
+ E IR + G G IL+GT +L+ SG T + QGH + E+
Sbjct: 943 RSALSTSSKGLLLEDNPSIRAITLGHGH-ILVGTKNGEILEIDKSGPMTLLVQGHMEGEV 1001
Query: 547 WGLAIHASKSQFLTCGHDKHATLWD-AVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLT 605
WGLA H T DK +W+ + HR + + ++ + F P G +AVG
Sbjct: 1002 WGLAAHPLLPICATVSDDKTLRIWELSAQHRMLAVRKLKKGGRCCAFSPDGKALAVGLND 1061
Query: 606 GRWFVFDTET-KDLVTVHTDGNEQLSVMRYSPD-GNFLAIGSHDNCIYIYGVSDNGRKYT 663
G + V + +T +D+V+ H E +S +++S D G +LA+ SHDN + IY V +
Sbjct: 1062 GSFLVVNADTVEDMVSFH-HRKEMISDIKFSKDTGKYLAVASHDNFVDIYNVLTS----K 1116
Query: 664 RVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW-VPSACKQVVSVETTRDIEWATYT 722
RVG C G SS+ITH+DW + L NSG E L++ P + ++ IEW T+T
Sbjct: 1117 RVGICKGASSYITHIDWDSRGKLLQVNSGAREQLFFEAPRGKRHIIRPSEIEKIEWDTWT 1176
Query: 723 CTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYGG 782
C LG G+WP SD TD+NA + LL+TGDDFG V LFSYP A Y G
Sbjct: 1177 CVLGPTCEGIWPAHSDITDVNAASLTKDCSLLATGDDFGFVKLFSYPVKGQHARFKKYVG 1236
Query: 783 HSSHVTNVDFLCEDSHLISTGGKDTSIMQW 812
HS+HVTNV +L DS L++ GG DT++M W
Sbjct: 1237 HSAHVTNVRWLHNDSVLLTVGGADTALMIW 1266
Score = 321 bits (822), Expect = 2e-87
Identities = 204/638 (31%), Positives = 320/638 (50%), Gaps = 33/638 (5%)
Query: 195 PVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYF-IASV 253
PV+ P+ + + K + + L L+ V+GYRG DCRNNL+ L G + F A+
Sbjct: 1337 PVSRAAPQPEKLQKNNITKKKKLVEELALDHVFGYRGFDCRNNLHYLNDGADIIFHTAAA 1396
Query: 254 VVLYNVEEQLQRHYAGHNDDVKCLAV--HPD-RITIATGQVAGTSKDGKQLPPHVRIWDS 310
++ N+ Q Y H DD+ CL V HP R +AT Q+ T P + IWD+
Sbjct: 1397 GIVQNLSTGSQSFYLEHTDDILCLTVNQHPKYRNVVATSQIGTT--------PSIHIWDA 1448
Query: 311 VTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCS 370
+T +TL ++ F + V I FS + G L +V +H ++VW WQ+ K+A
Sbjct: 1449 MTKHTLSMLRC-FHSKGVNYINFSAT--GKLLVSVGVDPEHTITVWRWQEGAKVASRGGH 1505
Query: 371 NEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEK--QEKPKFVLCVTFSE 428
E +F +F P V+ G H+ FWTL GS+L K+G+ K + +L V F
Sbjct: 1506 LERIFVVEFRPDSDTQFVSVGVKHMKFWTLAGSALLYKKGVIGSLGAAKMQTMLSVAFGA 1565
Query: 429 NGDTITGDSSGNILVWGKGTNRISYAVQGAHEGGIFAL-CMLRDGTLVSGGGKDRKLIS- 486
N T TG +G++ VW + + V AH G +F + LRDG +V+GG K+R
Sbjct: 1566 NNLTFTGAINGDVYVWKD--HFLIRLVAKAHTGPVFTMYTTLRDGLIVTGG-KERPTKEG 1622
Query: 487 -----WSGNYQKLR--KTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQ-GTLSGDFTPI 538
W ++ R + E + +R+V GKG IL+GT +++ G + +
Sbjct: 1623 GAVKLWDQEMKRCRAFQLETGQLVECVRSVCRGKGK-ILVGTKDGEIIEVGEKNAASNIL 1681
Query: 539 TQGHTD-ELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHPSGS 597
GH + E+WGLA H SK F++ +D A +WD + + + A+ + + P G
Sbjct: 1682 IDGHMEGEIWGLATHPSKDLFISASNDGTARIWDLADKKLLNKVSLGHAARCAAYSPDGE 1741
Query: 598 VVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSD 657
+VA+G G + + + + D + +R SPD FLA+GS ++ + Y ++
Sbjct: 1742 MVAIGMKNGEFVILLVNSLKVWGKKRDRKSAIQDIRISPDNRFLAVGSSEHTVDFYDLTQ 1801
Query: 658 NGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIE 717
G R+G C SF+ +D+S + +++ ++G Y+ KQV I
Sbjct: 1802 -GTNLNRIGYCKDIPSFVIQMDFSADGKYIQVSTGAYKRQVHEVPLGKQVTEAVVIEKIT 1860
Query: 718 WATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPS 777
WA++T LG V G+WP +D D+N C H + TGDDFG V LF +PC++ A
Sbjct: 1861 WASWTSVLGDEVIGIWPRNADKADVNCACVTHAGLNIVTGDDFGLVKLFDFPCTEKFAKH 1920
Query: 778 HIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI 815
Y GHS+HVTN+ F +D +++STGG D S+ WR +
Sbjct: 1921 KRYFGHSAHVTNIRFSYDDKYVVSTGGDDCSVFVWRCL 1958
>gi|34485720 echinoderm microtubule associated protein like 5 [Homo
sapiens]
Length = 1977
Score = 382 bits (982), Expect = e-106
Identities = 220/607 (36%), Positives = 343/607 (56%), Gaps = 27/607 (4%)
Query: 217 PTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKC 276
P+ L+LEWVYGYRG CRNNLY E VYF+A V V+Y+ E Q+ Y GH+DD+
Sbjct: 7 PSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIIS 66
Query: 277 LAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKS 336
LA+HP+R+ +ATGQV GK+ P++ IWDS T+ T+ V+ + C+AF
Sbjct: 67 LALHPERVLVATGQV------GKE--PYICIWDSYTVQTISVLK-DVHTHGIACLAFDLD 117
Query: 337 NGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLY 396
G L +V + + + VWDW++ + L+ + +F + N +V+CG H+
Sbjct: 118 --GQRLVSVGLDSKNAVCVWDWKRGKMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIK 175
Query: 397 FWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQ 456
FW+L G++L K+G+F K + +LC+ + + T +G +G+I VW KG N I +Q
Sbjct: 176 FWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVW-KGINLIR-TIQ 233
Query: 457 GAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQK-----LRKTEIPEQFGPIRTVAE 511
GAH GIF++ +G + GG+D + W ++ LR+T+ + +R+V
Sbjct: 234 GAHAAGIFSMNACEEG--FATGGRDGCIRLWDLTFKPITVIDLRETDQGYKGLSVRSVC- 290
Query: 512 GKGDVILIGTTRNFVLQGTLSGDFTP--ITQGHTD-ELWGLAIHASKSQFLTCGHDKHAT 568
+GD IL+GT + + + + P I QGH + ELW LA+H +K +T D+
Sbjct: 291 WRGDHILVGTQDSEIFEIVVQERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVR 350
Query: 569 LWDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQ 628
+W V H + +E+P + + + G +A+G G + V V D E
Sbjct: 351 IWSLVDHALIARCNMEEPIRCAAVNADGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEA 410
Query: 629 LSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLV 688
+ ++YSPDG +LA+G +D+ + IYGV+ ++Y +VG+C G SFITHLDWS +S++L
Sbjct: 411 IHELKYSPDGTYLAVGCNDSSVDIYGVA---QRYKKVGECLGSLSFITHLDWSSDSRYLQ 467
Query: 689 SNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRA 748
+N G+ + L++ K+V S E + + WA++TC G V G+WP+ SD DIN+V
Sbjct: 468 TNDGNGKRLFYRMPGGKEVTSTEEIKGVHWASWTCVSGLEVNGIWPKYSDINDINSVDGN 527
Query: 749 HEKKLLSTGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTS 808
+ ++L T DD+G + LF YPC + A Y GHS+HVTNV + + +IS GG D S
Sbjct: 528 YIGQVLVTADDYGIIKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHS 587
Query: 809 IMQWRVI 815
+ QW+ I
Sbjct: 588 VFQWKFI 594
Score = 341 bits (874), Expect = 2e-93
Identities = 222/660 (33%), Positives = 337/660 (51%), Gaps = 34/660 (5%)
Query: 176 KEPVFSAEEGYVKMFLRGR--PVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRD 233
KEP +G V RG PV+ P+ + + K + P + L LE ++GYRGRD
Sbjct: 1328 KEPSIDERQGVV----RGSRPPVSRAPPQPEKLQTNNVGKKKRPIEDLVLELIFGYRGRD 1383
Query: 234 CRNNLYLLPTGETV-YFIASVVVLYNVEEQLQRHYAGHNDDVKCLAV--HPDRITI-ATG 289
CRNN++ L G+ + Y ASV +L+NV Q Y HNDD+ CL V HP I I ATG
Sbjct: 1384 CRNNVHYLNDGDDIIYHTASVGILHNVATGSQSFYQEHNDDILCLTVNQHPKFINIVATG 1443
Query: 290 QVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSN 349
QV G S D P + IWD++ TL ++ + + V ++FS + G L +V
Sbjct: 1444 QV-GDSADMSATAPSIHIWDAMNKQTLSILRC-YHSKGVCSVSFSAT--GKLLLSVGLDP 1499
Query: 350 DHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQ 409
+H +++W WQ+ K+A N+ +F A+F P V+ G H+ FWTL G +L K+
Sbjct: 1500 EHTITIWRWQEGAKIASRAGHNQRIFVAEFRPDSDTQFVSVGVKHVKFWTLAGRALLSKK 1559
Query: 410 GLFEKQEKPKF--VLCVTFSENGDTITGDSSGNILVWGKGTNRISYAVQGAHEGGIFAL- 466
GL E + +L + F N T TG SG++ VW + + V AH G +FA+
Sbjct: 1560 GLLSTLEDARMQTMLAIAFGANNLTFTGTISGDVCVWKD--HILCRIVARAHNGPVFAMY 1617
Query: 467 CMLRDGTLVSGGGKDRK------LISWSGNYQKLR--KTEIPEQFGPIRTVAEGKGDVIL 518
LRDG +V+GG K+R + W ++ R + E + +R+V GKG IL
Sbjct: 1618 TTLRDGLIVTGG-KERPSKEGGAVKLWDQELRRCRAFRLETGQATDCVRSVCRGKGK-IL 1675
Query: 519 IGTTRNFVLQ-GTLSGDFTPITQGHTD-ELWGLAIHASKSQFLTCGHDKHATLWDAVGHR 576
+GT +++ G + + GH D +WGLA H S+ FL+ D LWD +
Sbjct: 1676 VGTRNAEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKK 1735
Query: 577 PVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSP 636
+ + A++ + P G +VA+G G + + + + D + +R+SP
Sbjct: 1736 MLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSP 1795
Query: 637 DGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEI 696
D +LA+GS +N + Y ++ G R+ C SF+ +D+S +S +L +SG Y+
Sbjct: 1796 DSRYLAVGSSENSVDFYDLT-LGPTLNRISYCKDIPSFVIQMDFSADSSYLQVSSGCYKR 1854
Query: 697 -LYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLS 755
+Y VPS K ++ I WAT+T LG V G+W ++ D+N C +H L
Sbjct: 1855 HVYEVPSG-KHLMDHAAIDRITWATWTSILGDEVLGIWSRHAEKADVNCACVSHSGISLV 1913
Query: 756 TGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRVI 815
TGDDFG V LF +PC + A + GHS HVTN+ F D H++S GG D S+ W+ +
Sbjct: 1914 TGDDFGMVKLFDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSLFVWKCV 1973
Score = 335 bits (859), Expect = 1e-91
Identities = 207/633 (32%), Positives = 326/633 (51%), Gaps = 46/633 (7%)
Query: 202 KDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEE 261
K++ S + + + P ++L +V+GYRG DCR+NL+ GE VY +A+V V+YN ++
Sbjct: 658 KEKQKSATSKRRERAPGNSIRLHFVHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQ 717
Query: 262 QLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGI 321
QR Y GH+DD+ CL +HP + +ATGQV P + IWD+ T+ L ++
Sbjct: 718 NTQRFYLGHDDDILCLTIHPLKDYVATGQVG--------RDPSIHIWDTETIKPLSILK- 768
Query: 322 GFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHP 381
G V+ + FS G L +V + H + +WDW+K EKL+ + S + +F +P
Sbjct: 769 GHHQYGVSAVDFSAD--GKRLASVGIDDSHTVVLWDWKKGEKLSIARGSKDKIFVVKMNP 826
Query: 382 TDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGD-TITGDSSGN 440
+ ++T G H+ FW G L ++G K ++C + + +G S+G+
Sbjct: 827 YVPDKLITAGIKHMKFWRKAGGGLIGRKGYIGTLGKNDTMMCAVYGWTEEMAFSGTSTGD 886
Query: 441 ILVWGKGTNRISYAVQ--GAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTE 498
+ +W R + V+ AH+G +F++ L G + GGKD + W ++++ KT
Sbjct: 887 VCIW-----RDIFLVKTVKAHDGPVFSMHALEKGFVT--GGKDGIVALWDDSFERCLKTY 939
Query: 499 --------------IPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQGHTD 544
+ E IR ++ G G IL+GT +L+ SG T + QGH +
Sbjct: 940 AIKRAALAPGSKGLLLEDNPSIRAISLGHGH-ILVGTKNGEILEVDKSGPITLLVQGHME 998
Query: 545 -ELWGLAIHASKSQFLTCGHDKHATLWD-AVGHRPVWDKIIEDPAQSSGFHPSGSVVAVG 602
E+WGLA H T DK +WD + H + + ++ + F P G +AVG
Sbjct: 999 GEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVG 1058
Query: 603 TLTGRWFVFDTET-KDLVTVHTDGNEQLSVMRYSP-DGNFLAIGSHDNCIYIYGVSDNGR 660
G + + + +T +DLV+ H + +S +R+SP G +LA+ SHD+ I IY V +
Sbjct: 1059 LNDGSFLMANADTLEDLVSFH-HRKDMISDIRFSPGSGKYLAVASHDSFIDIYNVMSS-- 1115
Query: 661 KYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW-VPSACKQVVSVETTRDIEWA 719
RVG C G +S+ITH+DW + + L N+G E L++ P KQ + I WA
Sbjct: 1116 --KRVGICKGATSYITHIDWDIRGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKIAWA 1173
Query: 720 TYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCSQFRAPSHI 779
++T LG G+WP + TD+ A C +K +L+TGDD G V LF YP
Sbjct: 1174 SWTSVLGLCCEGIWPVIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPTKGKFGKFKR 1233
Query: 780 YGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQW 812
Y HS+HVTNV + +DS L++ GG D S+M W
Sbjct: 1234 YVAHSTHVTNVRWTYDDSMLVTLGGTDMSLMVW 1266
>gi|31377846 WD repeat domain 52 [Homo sapiens]
Length = 982
Score = 85.1 bits (209), Expect = 2e-16
Identities = 124/609 (20%), Positives = 229/609 (37%), Gaps = 85/609 (13%)
Query: 118 RKETAVPATKSNIKRTSSSERVSPGGRRESNGDSRGNRNRTGSTSSSSSGKKNSESKPKE 177
+ E+ P + N ++ G + GS SS G S + P++
Sbjct: 29 KSESRSPVQEDNTFLEDDTDETFTKGEGSYLEEDSDEERLEGSLSSFQYGDLQSTTVPQQ 88
Query: 178 ---PVFSAEEGYVKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDC 234
P E VK + YM + +L++ + P L L +GY DC
Sbjct: 89 TPAPAVEEAEEEVKKKISESFFYDYMELASMPFVTLDSNI--PLDLLTLVHSFGY---DC 143
Query: 235 RN--NLYLLPTGETVYFIASVVVLYNVEEQLQRHY-AGHNDDVKCLAVHPDRITIATGQV 291
R NL LL +Y + ++ N++ + Q + + + + + VHP + +
Sbjct: 144 RKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAE- 202
Query: 292 AGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDH 351
K P + I++ +L V+ G ++ + F+ S G L +V + D+
Sbjct: 203 -------KGSFPDIIIYEYPSLRPYRVLRDGT-EKGYAYVDFNYS--GNLLASVGSNPDY 252
Query: 352 VLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFW----TLEGSSLNK 407
L++W+W++E+ + K ++ VF F+P + T G H+ FW T G L
Sbjct: 253 TLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQG 312
Query: 408 KQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVWGKGTNRISY---AVQGAHEGGIF 464
G F K + + G ++G GN+L+W G ++ + H G I
Sbjct: 313 SLGRFGKTITTDIEGYMELPD-GKVLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGPIN 371
Query: 465 ALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFG-----PIRTVAEGK-----G 514
+ ML +G +++ G D + W +++ + ++ ++ G PI + K
Sbjct: 372 QI-MLYEGEVIT-VGSDGYVRIW--DFETIDTADVIDETGLLEIEPINELQVDKNVNLFS 427
Query: 515 DVILIGTTRNFVLQGTLSG-------DFTPITQG-------HTDELWGLAIHASKSQFLT 560
+ + T NF L +G F+ ITQ H+ + +A+ T
Sbjct: 428 MIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSPLTYLMAT 487
Query: 561 CGHDKHATLWDAVGHRPVWDKIIEDPAQSSGFHP-----SGSVVAVG------------- 602
D ++D P+ + + + P +G+ + VG
Sbjct: 488 TALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRILELYD 547
Query: 603 -----TLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSD 657
GR + D + + L V ++ + Y DG LA GS D ++ + V
Sbjct: 548 PKGLTIFAGRKKILDADIQ-LKQVFKPHTACVTALAYERDGEILATGSKDQTVFFFEVE- 605
Query: 658 NGRKYTRVG 666
R Y +G
Sbjct: 606 --RDYKPIG 612
>gi|94400919 WD repeat domain 90 [Homo sapiens]
Length = 1748
Score = 73.6 bits (179), Expect = 7e-13
Identities = 101/481 (20%), Positives = 169/481 (35%), Gaps = 58/481 (12%)
Query: 216 LPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVK 275
LP L+L+ V G+ G R L+ VY +V+V+ V+ QR + GH D V
Sbjct: 354 LPDPVLRLKGVIGFGGHGTRQALWTPDGAAVVYPCHAVIVVLLVDTGEQRFFLGHTDKVS 413
Query: 276 CLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSK 335
LA+ +A+ Q + P +R+WD T L + F + S
Sbjct: 414 ALALDGSSSLLASAQA--------RAPSVMRLWDFQTGRCLCL----FRSPMHVVCSLSF 461
Query: 336 SNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPT-----------DT 384
S+ G LC V + V W V E V A H D
Sbjct: 462 SDSGALLCGVGKDHHGRTMVVAW----GTGQVGLGGEVVVLAKAHTDFDVQAFRVTFFDE 517
Query: 385 NIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNILVW 444
+ +CG+ + W L G L + +F + F + D S+ + V
Sbjct: 518 TRMASCGQGSVRLWRLRGGVLRSCPVDLGEHHALQFT-DLAFKQARDGCPEPSAAMLFVC 576
Query: 445 GKGTNRISYAVQ-----------------GAHE--------GGIFALCMLRDGTLVSGGG 479
+ + + Q G H GI + + + G
Sbjct: 577 SRSGHILEIDCQRMVVRHARRLLPTRTPGGPHPQKQTFSSGPGIAISSLSVSPAMCAVGS 636
Query: 480 KDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVL--QGTLSGDFTP 537
+D L W ++ + E GP+ +V + ++ T + L TLS +
Sbjct: 637 EDGFLRLWPLDFSSVLLE--AEHEGPVSSVCVSPDGLRVLSATSSGHLGFLDTLSRVYHM 694
Query: 538 ITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWD-KIIEDPAQSSGFHPSG 596
+ + HT + LA+ + Q T D+ +WD + ++D ED + FHP+
Sbjct: 695 LARSHTAPVLALAMEQRRGQLATVSQDRTVRIWDLATLQQLYDFTSSEDAPCAVTFHPTR 754
Query: 597 SVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVS 656
G +G F E +++ HT ++ + +PDG L + Y +
Sbjct: 755 PTFFCGFSSGAVRSFSLEAAEVLVEHTCHRGAVTGLTATPDGRLLFSSCSQGSLAQYSCA 814
Query: 657 D 657
D
Sbjct: 815 D 815
Score = 73.2 bits (178), Expect = 9e-13
Identities = 78/369 (21%), Positives = 146/369 (39%), Gaps = 33/369 (8%)
Query: 221 LKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAGHNDDVKCLAVH 280
L+L+ V GY G N ++ TG Y +VV+ ++ Q+H++GH+ ++ LA+
Sbjct: 1108 LRLKAVVGYSGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSGAQQHWSGHSAEISTLALS 1167
Query: 281 PDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGT 340
+A + + + +R+WD H+I F + T +A + S
Sbjct: 1168 HSAQVLA----SASGRSSTTAHCQIRVWDVSGGLCQHLI----FPHSTTVLALAFSPDDR 1219
Query: 341 NLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTL 400
L + D + L++W + ++ + E V F+P D + G+ + FW L
Sbjct: 1220 LLVTLGDHDGRTLALWGTATYDLVSSTRLP-EPVHGVAFNPWDAGELTCVGQGTVTFWLL 1278
Query: 401 E--GSSLNKKQGLFEKQEKPKFV-----LCVTFSENGDTITGDSSGNILVWGKGTNRISY 453
+ G+ ++ + ++ P+ V + + G SSG + VW R
Sbjct: 1279 QQRGADISLQ---VRREPVPEAVGAGELTSLCYGAPPLLYCGTSSGQVCVWDTRAGRCFL 1335
Query: 454 AVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLR-----------KTEIPEQ 502
+ + A +GGI L + LVSG R + G +LR + E+
Sbjct: 1336 SWE-ADDGGI-GLLLFSGSRLVSGSSTGRLRLWAVGAVSELRCKGSGASSVFMEHELVLD 1393
Query: 503 FGPIRTVAEGKGDVILIGTTRNFV-LQGTLSGDFTPITQGHTDELWGLAIHASKSQFLTC 561
+ + D+ ++GTT + G T + GH ++ + +S TC
Sbjct: 1394 GAVVSASFDDSVDMGVVGTTAGTLWFVSWAEGTSTRLISGHRSKVNEVVFSPGESHCATC 1453
Query: 562 GHDKHATLW 570
D +W
Sbjct: 1454 SEDGSVRVW 1462
>gi|190684677 mitogen-activated protein kinase binding protein 1
isoform b [Homo sapiens]
Length = 1514
Score = 71.6 bits (174), Expect = 3e-12
Identities = 180/761 (23%), Positives = 269/761 (35%), Gaps = 173/761 (22%)
Query: 187 VKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDC--RNNLYLLPTG 244
+K LR + + K L +KV L K L + V G RG C R+ L P G
Sbjct: 12 IKNLLRSPSIKLRRSKAGNRREDLSSKVTLE-KVLGIT-VSGGRGLACDPRSGLVAYPAG 69
Query: 245 ETVYFIASVVVLYNVEEQLQRHYAGHN-DDVKCLAVHPDRITIATGQVAGTSKDGKQLPP 303
VVVL+N + Q H + + LA PD + TG+ P
Sbjct: 70 -------CVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHM--------P 114
Query: 304 HVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEK 363
VR+WD + V + V C+AFS S + +V +D +++VW W+K
Sbjct: 115 AVRVWDVAEHS--QVAELQEHKYGVACVAFSPS--AKYIVSVGYQHDMIVNVWAWKKNIV 170
Query: 364 LADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNK---------KQGLFEK 414
+A K S+ V A F D + VT G H+ FW L+ S +K + GL +
Sbjct: 171 VASNKVSSR-VTAVSFSE-DCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGE 228
Query: 415 QEKPKF--VLCVTFSENGDTITGDSSGNIL---------VWGKGTNRISYAVQGAHEGGI 463
F V C + T SSG + W + N S+ AH +
Sbjct: 229 LRNNLFTDVACGRGKKADSTFCITSSGLLCEFSDRRLLDKWVELRNIDSFTTTVAHCISV 288
Query: 464 ---FALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFG-PIRTVAEGKGDVILI 519
+ C DGT+ +L + S N L P G I +V E L
Sbjct: 289 SQDYIFCGCADGTV--------RLFNPS-NLHFLSTLPRPHALGTDIASVTEASR---LF 336
Query: 520 GTTRNFVLQGTLSGDFTPITQG-----------------------------HTDELWGLA 550
N T++ F P Q H+ +W +
Sbjct: 337 SGVANARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVE 396
Query: 551 IHAS----------KSQFLTCGHDKHATLWDAVG--------HRPVWD----KII----- 583
++ S F+TC D LW+ HR + KII
Sbjct: 397 VYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGN 456
Query: 584 -----------EDPAQSSGFHP-----------SGSVVAVGTLTGRWFVFDTET-KDLVT 620
D A +S P +G +A G G V + ++ +++
Sbjct: 457 TQALLDTELPGGDKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLK 516
Query: 621 VHTDGNEQLSVMRYSPDG--NFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHL 678
V +E L + PD LA S D I+ V D GR+Y+ HSS IT +
Sbjct: 517 VEAHDSEILCLEYSKPDTGLKLLASASRDRLIH---VLDAGREYSLQQTLDEHSSSITAV 573
Query: 679 DWSV-NSQFLVSNSGDYEILYWVPSACKQVVSVETTRDIEWATYTCTLGFHVFGVWPEGS 737
++ + Q + + G + +Y+ +A K V+ TR T V W +
Sbjct: 574 KFAASDGQVRMISCGADKSIYF-RTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTA 632
Query: 738 DGTD-----INAVCRAHEKKLL--STGDDFGKVHLFSYPCSQFRAPS------HIYG--- 781
G I + +KKL S G+D + + + P + A S I+
Sbjct: 633 IGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSS 692
Query: 782 --------GHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRV 814
GHS VT + F + HLIS G D+ I WR+
Sbjct: 693 GECVATMFGHSEIVTGMKFSNDCKHLISVSG-DSCIFVWRL 732
Score = 30.8 bits (68), Expect = 5.3
Identities = 17/63 (26%), Positives = 31/63 (49%)
Query: 594 PSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIY 653
PSG +A +FD + + V +E ++ M++S D L S D+CI+++
Sbjct: 671 PSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVW 730
Query: 654 GVS 656
+S
Sbjct: 731 RLS 733
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 71.2 bits (173), Expect = 4e-12
Identities = 69/288 (23%), Positives = 122/288 (42%), Gaps = 47/288 (16%)
Query: 462 GIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKT--------------EIPEQFGPIR 507
G+ A+ + D +L++GG D + WS +KLR ++ E+ +
Sbjct: 472 GLTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASDLSLIDKESDDVLERIMDEK 531
Query: 508 TVAEGKGDVILIGTT-----------RNFVLQGTLSGD--------FTPIT--QGHTDEL 546
T +E K IL G + RN++L + G FT + +GH +
Sbjct: 532 TASELK---ILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPV 588
Query: 547 WGLAIHASKSQFLTCGHDKHATLWDAVGHRP--VWDKIIEDPAQSSGFHPSGSVVAVGTL 604
W F++ GHD+ A LW ++P ++ + D + FHP+ + VA G+
Sbjct: 589 WDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLAD-VNCTRFHPNSNYVATGSA 647
Query: 605 TGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTR 664
++D + V + T + + +SP+G FLA G+ D + ++ +
Sbjct: 648 DRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHG----LM 703
Query: 665 VGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQVVSVET 712
VG+ GH+ + L +S + + L S S D + W A K +ET
Sbjct: 704 VGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW--DAIKAFEDLET 749
Score = 44.3 bits (103), Expect = 5e-04
Identities = 55/228 (24%), Positives = 88/228 (38%), Gaps = 39/228 (17%)
Query: 269 GHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAV 328
GH+ V + PDR + +S+DG VR+W T L +G + V
Sbjct: 541 GHSGPVYGASFSPDR-----NYLLSSSEDGT-----VRLWSLQTFTCL--VGYKGHNYPV 588
Query: 329 TCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKL-------ADVKCSNEAVFAADFHP 381
FS V +D V +W + L ADV C+ FHP
Sbjct: 589 WDTQFSPYG----YYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTR-------FHP 637
Query: 382 TDTNIIVTCGKSHLYFW-TLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSG 439
+ + W L G+ + +F + P + +TFS NG + TG + G
Sbjct: 638 NSNYVATGSADRTVRLWDVLNGNCVR----IFTGHKGP--IHSLTFSPNGRFLATGATDG 691
Query: 440 NILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISW 487
+L+W G + ++G H + +L RDG +++ G D + W
Sbjct: 692 RVLLWDIGHGLMVGELKG-HTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 33.1 bits (74), Expect = 1.1
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 10/54 (18%)
Query: 265 RHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHV 318
R +AGH DV C HP+ +ATG T VR+WD + N + +
Sbjct: 621 RIFAGHLADVNCTRFHPNSNYVATGSADRT----------VRLWDVLNGNCVRI 664
>gi|145580608 WD repeat domain 62 isoform 1 [Homo sapiens]
Length = 1523
Score = 70.5 bits (171), Expect = 6e-12
Identities = 62/198 (31%), Positives = 93/198 (46%), Gaps = 17/198 (8%)
Query: 212 AKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRH-YAGH 270
A E R+ LE V G ++ TG Y VVV+ + +E Q+H +
Sbjct: 51 ASEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTA 110
Query: 271 NDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTL-HVIGIGFFDRAVT 329
+ LA PD I TG+ +G + P VRIWD N + ++G + V
Sbjct: 111 RKSLSALAFSPDGKYIVTGE------NGHR--PAVRIWDVEEKNQVAEMLGHKY---GVA 159
Query: 330 CIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVT 389
C+AFS + ++ ++ +D VL+VWDW+K+ +A K S V A F D++ VT
Sbjct: 160 CVAFSPNM--KHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCR-VIALSF-SEDSSYFVT 215
Query: 390 CGKSHLYFWTLEGSSLNK 407
G H+ FW LE S+ K
Sbjct: 216 VGNRHVRFWFLEVSTETK 233
Score = 32.0 bits (71), Expect = 2.4
Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 623 TDGNE-QLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWS 681
+ G+E L + P G FLA D I + + K GHS IT + ++
Sbjct: 669 SQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSG----ECIAKMFGHSEIITSMKFT 724
Query: 682 VNSQFLVSNSGDYEILYW 699
+ L++ SGD + W
Sbjct: 725 YDCHHLITVSGDSCVFIW 742
Score = 31.6 bits (70), Expect = 3.1
Identities = 33/142 (23%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
Query: 571 DAVGHRPVWDKIIEDPAQ-SSGFHPSGSVVAVGTLTGRWFVF-DTETKDLVTVHTDGNEQ 628
+ V +R +K++ AQ SSG V L G V D + + +
Sbjct: 54 ETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKS 113
Query: 629 LSVMRYSPDGNFLAIG--SHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQF 686
LS + +SPDG ++ G H + I+ V + +V + GH + + +S N +
Sbjct: 114 LSALAFSPDGKYIVTGENGHRPAVRIWDVEEK----NQVAEMLGHKYGVACVAFSPNMKH 169
Query: 687 LVSNSGDYEILYWVPSACKQVV 708
+VS ++++ V K +V
Sbjct: 170 IVSMGYQHDMVLNVWDWKKDIV 191
>gi|145580610 WD repeat domain 62 isoform 2 [Homo sapiens]
Length = 1518
Score = 70.5 bits (171), Expect = 6e-12
Identities = 62/198 (31%), Positives = 93/198 (46%), Gaps = 17/198 (8%)
Query: 212 AKVELPTKRLKLEWVYGYRGRDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRH-YAGH 270
A E R+ LE V G ++ TG Y VVV+ + +E Q+H +
Sbjct: 51 ASEETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTA 110
Query: 271 NDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTL-HVIGIGFFDRAVT 329
+ LA PD I TG+ +G + P VRIWD N + ++G + V
Sbjct: 111 RKSLSALAFSPDGKYIVTGE------NGHR--PAVRIWDVEEKNQVAEMLGHKY---GVA 159
Query: 330 CIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVT 389
C+AFS + ++ ++ +D VL+VWDW+K+ +A K S V A F D++ VT
Sbjct: 160 CVAFSPNM--KHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCR-VIALSF-SEDSSYFVT 215
Query: 390 CGKSHLYFWTLEGSSLNK 407
G H+ FW LE S+ K
Sbjct: 216 VGNRHVRFWFLEVSTETK 233
Score = 32.0 bits (71), Expect = 2.4
Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 623 TDGNE-QLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWS 681
+ G+E L + P G FLA D I + + K GHS IT + ++
Sbjct: 669 SQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSG----ECIAKMFGHSEIITSMKFT 724
Query: 682 VNSQFLVSNSGDYEILYW 699
+ L++ SGD + W
Sbjct: 725 YDCHHLITVSGDSCVFIW 742
Score = 31.6 bits (70), Expect = 3.1
Identities = 33/142 (23%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
Query: 571 DAVGHRPVWDKIIEDPAQ-SSGFHPSGSVVAVGTLTGRWFVF-DTETKDLVTVHTDGNEQ 628
+ V +R +K++ AQ SSG V L G V D + + +
Sbjct: 54 ETVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILDPKENKQQHIFNTARKS 113
Query: 629 LSVMRYSPDGNFLAIG--SHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQF 686
LS + +SPDG ++ G H + I+ V + +V + GH + + +S N +
Sbjct: 114 LSALAFSPDGKYIVTGENGHRPAVRIWDVEEK----NQVAEMLGHKYGVACVAFSPNMKH 169
Query: 687 LVSNSGDYEILYWVPSACKQVV 708
+VS ++++ V K +V
Sbjct: 170 IVSMGYQHDMVLNVWDWKKDIV 191
>gi|190684671 mitogen-activated protein kinase binding protein 1
isoform a [Homo sapiens]
Length = 1508
Score = 63.2 bits (152), Expect = 1e-09
Identities = 66/224 (29%), Positives = 95/224 (42%), Gaps = 26/224 (11%)
Query: 187 VKMFLRGRPVTMYMPKDQVDSYSLEAKVELPTKRLKLEWVYGYRGRDC--RNNLYLLPTG 244
+K LR + + K L +KV L K L + V G RG C R+ L P G
Sbjct: 12 IKNLLRSPSIKLRRSKAGNRREDLSSKVTLE-KVLGIT-VSGGRGLACDPRSGLVAYPAG 69
Query: 245 ETVYFIASVVVLYNVEEQLQRHYAGHN-DDVKCLAVHPDRITIATGQVAGTSKDGKQLPP 303
VVVL+N + Q H + + LA PD + TG+ P
Sbjct: 70 -------CVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHM--------P 114
Query: 304 HVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEK 363
VR+WD + V + V C+AFS S + +V +D +++VW W+K
Sbjct: 115 AVRVWDVAEHS--QVAELQEHKYGVACVAFSPS--AKYIVSVGYQHDMIVNVWAWKKNIV 170
Query: 364 LADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNK 407
+A K S+ V A F D + VT G H+ FW L+ S +K
Sbjct: 171 VASNKVSSR-VTAVSFSE-DCSYFVTAGNRHIKFWYLDDSKTSK 212
Score = 40.0 bits (92), Expect = 0.009
Identities = 63/249 (25%), Positives = 101/249 (40%), Gaps = 33/249 (13%)
Query: 594 PSGSVVAVGTLTGRWFVFDTET-KDLVTVHTDGNEQLSVMRYSPDGNF--LAIGSHDNCI 650
P+G +A G G V + ++ +++ V +E L + PD LA S D I
Sbjct: 483 PNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLI 542
Query: 651 YIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNS-QFLVSNSGDYEILYWVPSACKQVVS 709
++ D GR+Y+ HSS IT + ++ + Q + + G + +Y+ +A K
Sbjct: 543 HVL---DAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYF-RTAQKSGDG 598
Query: 710 VETTRDIEWATYTCTLGFHVFGVWPEGSDGTD-----INAVCRAHEKKLL--STGDDFGK 762
V+ TR T V W + G I + +KKL S G+D
Sbjct: 599 VQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTL 658
Query: 763 VHLFSYPCSQFRAPS------HIYG-----------GHSSHVTNVDFLCEDSHLISTGGK 805
+ + + P + A S I+ GHS VT + F + HLIS G
Sbjct: 659 IKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSG- 717
Query: 806 DTSIMQWRV 814
D+ I WR+
Sbjct: 718 DSCIFVWRL 726
Score = 33.1 bits (74), Expect = 1.1
Identities = 74/384 (19%), Positives = 137/384 (35%), Gaps = 50/384 (13%)
Query: 349 NDHVLSVWDWQKEEKLADVKCS---NEAVFAADFHPT--DTN-------IIVTCGKSH-L 395
NDH + VWD + +K+ V + + V++ + +P D+N +TC + +
Sbjct: 358 NDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTI 417
Query: 396 YFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTIT------GDSSGNILVWGK-GT 448
W E S ++ L + + N + GD + L+ + G
Sbjct: 418 RLWNTESSGVHGST-LHRNILSSDLIKIIYVDGNTQALLDTELPGGDKADASLLDPRVGI 476
Query: 449 NRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFGPIRT 508
+ + G H + LR L S +++ + ++ E + ++
Sbjct: 477 RSVCVSPNGQHLASGDRMGTLRVHELQSLS----EMLKVEAHDSEILCLEYSKPDTGLKL 532
Query: 509 VAEGKGDVIL--IGTTRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKSQ--FLTCGHD 564
+A D ++ + R + LQ TL H+ + + AS Q ++CG D
Sbjct: 533 LASASRDRLIHVLDAGREYSLQQTLDE--------HSSSITAVKFAASDGQVRMISCGAD 584
Query: 565 KHATL------WDAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTET--- 615
K D V + + PS A+G +F+ +
Sbjct: 585 KSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQ 644
Query: 616 KDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFI 675
K L + L ++ P G ++A D + I+ S V GHS +
Sbjct: 645 KKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSG----ECVATMFGHSEIV 700
Query: 676 THLDWSVNSQFLVSNSGDYEILYW 699
T + +S + + L+S SGD I W
Sbjct: 701 TGMKFSNDCKHLISVSGDSCIFVW 724
Score = 30.8 bits (68), Expect = 5.3
Identities = 17/63 (26%), Positives = 31/63 (49%)
Query: 594 PSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIY 653
PSG +A +FD + + V +E ++ M++S D L S D+CI+++
Sbjct: 665 PSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVW 724
Query: 654 GVS 656
+S
Sbjct: 725 RLS 727
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 62.4 bits (150), Expect = 2e-09
Identities = 68/302 (22%), Positives = 117/302 (38%), Gaps = 26/302 (8%)
Query: 374 VFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEK-------QEKP--KFVLCV 424
VF ++P + G S W L +S + L + Q+ P K V +
Sbjct: 172 VFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSL 231
Query: 425 TFSENGDTI-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRK 483
++ G + TG G +W K N S G H+G IFAL + G + G D+
Sbjct: 232 DWNSEGTLLATGSYDGFARIWTKDGNLAS--TLGQHKGPIFALKWNKKGNFILSAGVDKT 289
Query: 484 LISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPIT--QG 541
I W + + K + P P V + + + + + + G PI QG
Sbjct: 290 TIIWDAHTGEA-KQQFPFHSAPALDV-DWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQG 347
Query: 542 HTDELWGLAIHASKSQFLTCGHDKHATLW---------DAVGHRPVWDKIIEDPAQSSGF 592
HT+E+ + + + +C D +W D H I P
Sbjct: 348 HTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTN 407
Query: 593 HPSGSVV-AVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIY 651
+P+ +++ A + ++D + + T E + + +SPDG +LA GS D C++
Sbjct: 408 NPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVH 467
Query: 652 IY 653
I+
Sbjct: 468 IW 469
Score = 36.6 bits (83), Expect = 0.096
Identities = 31/145 (21%), Positives = 64/145 (44%), Gaps = 19/145 (13%)
Query: 348 SNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPT-------DTNIIVTCGK--SHLYFW 398
S+D L +W +++ + D++ N+ ++ + PT + N+++ S + W
Sbjct: 368 SDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLW 427
Query: 399 TLE-GSSLNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQ 456
++ G ++ K ++P V V FS +G + +G + +W T + ++ +
Sbjct: 428 DVDRGICIH----TLTKHQEP--VYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYR 481
Query: 457 GAHEGGIFALCMLRDGTLVSGGGKD 481
G GGIF +C G V D
Sbjct: 482 GT--GGIFEVCWNAAGDKVGASASD 504
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 62.0 bits (149), Expect = 2e-09
Identities = 68/302 (22%), Positives = 113/302 (37%), Gaps = 26/302 (8%)
Query: 374 VFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQ---------EKPKFVLCV 424
VF ++P + G S W L +S L + K V +
Sbjct: 184 VFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSL 243
Query: 425 TFSENGDTI-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRK 483
++ NG + TG G +W + N S G H+G IFAL R G + G D+
Sbjct: 244 DWNTNGTLLATGSYDGFARIWTEDGNLAS--TLGQHKGPIFALKWNRKGNYILSAGVDKT 301
Query: 484 LISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPIT--QG 541
I W + + K + P P V + + + + + + G P+ QG
Sbjct: 302 TIIWDAHTGEA-KQQFPFHSAPALDV-DWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQG 359
Query: 542 HTDELWGLAIHASKSQFLTCGHDKHATLW---------DAVGHRPVWDKIIEDPAQSSGF 592
HT+E+ + S +C D +W D H I P +
Sbjct: 360 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS 419
Query: 593 HPSGSVV-AVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIY 651
+P+ +++ A + ++D E T E + + +SPDG +LA GS D C++
Sbjct: 420 NPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVH 479
Query: 652 IY 653
I+
Sbjct: 480 IW 481
Score = 39.7 bits (91), Expect = 0.011
Identities = 32/144 (22%), Positives = 62/144 (43%), Gaps = 17/144 (11%)
Query: 348 SNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPT-------DTNIIVTCGK--SHLYFW 398
S+D L +W ++E + D++ N+ ++ + PT ++NI++ S + W
Sbjct: 380 SDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 439
Query: 399 TLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQG 457
+E K ++P V V FS +G + +G + +W + + ++ +G
Sbjct: 440 DIERGVCTH---TLTKHQEP--VYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 494
Query: 458 AHEGGIFALCMLRDGTLVSGGGKD 481
GGIF +C G V D
Sbjct: 495 T--GGIFEVCWNARGDKVGASASD 516
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 62.0 bits (149), Expect = 2e-09
Identities = 68/302 (22%), Positives = 113/302 (37%), Gaps = 26/302 (8%)
Query: 374 VFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQ---------EKPKFVLCV 424
VF ++P + G S W L +S L + K V +
Sbjct: 184 VFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSL 243
Query: 425 TFSENGDTI-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRK 483
++ NG + TG G +W + N S G H+G IFAL R G + G D+
Sbjct: 244 DWNTNGTLLATGSYDGFARIWTEDGNLAS--TLGQHKGPIFALKWNRKGNYILSAGVDKT 301
Query: 484 LISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPIT--QG 541
I W + + K + P P V + + + + + + G P+ QG
Sbjct: 302 TIIWDAHTGEA-KQQFPFHSAPALDV-DWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQG 359
Query: 542 HTDELWGLAIHASKSQFLTCGHDKHATLW---------DAVGHRPVWDKIIEDPAQSSGF 592
HT+E+ + S +C D +W D H I P +
Sbjct: 360 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS 419
Query: 593 HPSGSVV-AVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIY 651
+P+ +++ A + ++D E T E + + +SPDG +LA GS D C++
Sbjct: 420 NPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVH 479
Query: 652 IY 653
I+
Sbjct: 480 IW 481
Score = 39.7 bits (91), Expect = 0.011
Identities = 32/144 (22%), Positives = 62/144 (43%), Gaps = 17/144 (11%)
Query: 348 SNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPT-------DTNIIVTCGK--SHLYFW 398
S+D L +W ++E + D++ N+ ++ + PT ++NI++ S + W
Sbjct: 380 SDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 439
Query: 399 TLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQG 457
+E K ++P V V FS +G + +G + +W + + ++ +G
Sbjct: 440 DIERGVCTH---TLTKHQEP--VYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 494
Query: 458 AHEGGIFALCMLRDGTLVSGGGKD 481
GGIF +C G V D
Sbjct: 495 T--GGIFEVCWNARGDKVGASASD 516
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 62.0 bits (149), Expect = 2e-09
Identities = 68/302 (22%), Positives = 113/302 (37%), Gaps = 26/302 (8%)
Query: 374 VFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQ---------EKPKFVLCV 424
VF ++P + G S W L +S L + K V +
Sbjct: 235 VFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSL 294
Query: 425 TFSENGDTI-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRK 483
++ NG + TG G +W + N S G H+G IFAL R G + G D+
Sbjct: 295 DWNTNGTLLATGSYDGFARIWTEDGNLAS--TLGQHKGPIFALKWNRKGNYILSAGVDKT 352
Query: 484 LISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPIT--QG 541
I W + + K + P P V + + + + + + G P+ QG
Sbjct: 353 TIIWDAHTGEA-KQQFPFHSAPALDV-DWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQG 410
Query: 542 HTDELWGLAIHASKSQFLTCGHDKHATLW---------DAVGHRPVWDKIIEDPAQSSGF 592
HT+E+ + S +C D +W D H I P +
Sbjct: 411 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS 470
Query: 593 HPSGSVV-AVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIY 651
+P+ +++ A + ++D E T E + + +SPDG +LA GS D C++
Sbjct: 471 NPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVH 530
Query: 652 IY 653
I+
Sbjct: 531 IW 532
Score = 39.7 bits (91), Expect = 0.011
Identities = 32/144 (22%), Positives = 62/144 (43%), Gaps = 17/144 (11%)
Query: 348 SNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPT-------DTNIIVTCGK--SHLYFW 398
S+D L +W ++E + D++ N+ ++ + PT ++NI++ S + W
Sbjct: 431 SDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 490
Query: 399 TLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQG 457
+E K ++P V V FS +G + +G + +W + + ++ +G
Sbjct: 491 DIERGVCTH---TLTKHQEP--VYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 545
Query: 458 AHEGGIFALCMLRDGTLVSGGGKD 481
GGIF +C G V D
Sbjct: 546 T--GGIFEVCWNARGDKVGASASD 567
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 62.0 bits (149), Expect = 2e-09
Identities = 68/302 (22%), Positives = 113/302 (37%), Gaps = 26/302 (8%)
Query: 374 VFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQ---------EKPKFVLCV 424
VF ++P + G S W L +S L + K V +
Sbjct: 235 VFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSL 294
Query: 425 TFSENGDTI-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRK 483
++ NG + TG G +W + N S G H+G IFAL R G + G D+
Sbjct: 295 DWNTNGTLLATGSYDGFARIWTEDGNLAS--TLGQHKGPIFALKWNRKGNYILSAGVDKT 352
Query: 484 LISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPIT--QG 541
I W + + K + P P V + + + + + + G P+ QG
Sbjct: 353 TIIWDAHTGEA-KQQFPFHSAPALDV-DWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQG 410
Query: 542 HTDELWGLAIHASKSQFLTCGHDKHATLW---------DAVGHRPVWDKIIEDPAQSSGF 592
HT+E+ + S +C D +W D H I P +
Sbjct: 411 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS 470
Query: 593 HPSGSVV-AVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIY 651
+P+ +++ A + ++D E T E + + +SPDG +LA GS D C++
Sbjct: 471 NPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVH 530
Query: 652 IY 653
I+
Sbjct: 531 IW 532
Score = 39.7 bits (91), Expect = 0.011
Identities = 32/144 (22%), Positives = 62/144 (43%), Gaps = 17/144 (11%)
Query: 348 SNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPT-------DTNIIVTCGK--SHLYFW 398
S+D L +W ++E + D++ N+ ++ + PT ++NI++ S + W
Sbjct: 431 SDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLW 490
Query: 399 TLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQG 457
+E K ++P V V FS +G + +G + +W + + ++ +G
Sbjct: 491 DIERGVCTH---TLTKHQEP--VYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 545
Query: 458 AHEGGIFALCMLRDGTLVSGGGKD 481
GGIF +C G V D
Sbjct: 546 T--GGIFEVCWNARGDKVGASASD 567
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 60.8 bits (146), Expect = 5e-09
Identities = 64/301 (21%), Positives = 117/301 (38%), Gaps = 41/301 (13%)
Query: 538 ITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAV---------GHRPVWDKIIEDPAQ 588
+ + H L +A++ S S F+T +D+ LWD GHR V I +
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN--- 143
Query: 589 SSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDN 648
+P G +A G+ ++ ET ++ + ++P +A GS D
Sbjct: 144 ----NPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDT 199
Query: 649 CIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWVPSACKQV- 707
++ + + YT GHS+ I L ++ + +++ S D+ ++ W ++V
Sbjct: 200 TAKLWDIQNGEEVYT----LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVN 255
Query: 708 VSVETTRDIEWATY--------------TCTLGFHVFGVWPEGSDGTD--INAVCRAHEK 751
+ + +I A++ TC L G G D I C +
Sbjct: 256 ILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTG 315
Query: 752 KLLSTGDDFGKVHLFSYPCSQFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQ 811
KL++T G +FS + A GH ++ + F + +HL+ TG D +
Sbjct: 316 KLIATASADGTARIFSAATRKCIAKLE---GHEGEISKISFNPQGNHLL-TGSSDKTARI 371
Query: 812 W 812
W
Sbjct: 372 W 372
Score = 57.8 bits (138), Expect = 4e-08
Identities = 74/380 (19%), Positives = 130/380 (34%), Gaps = 68/380 (17%)
Query: 328 VTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFH-PTDTNI 386
+T +A +KS C + S D +WD E+L ++ V+A F+ P I
Sbjct: 95 LTNVALNKSGS----CFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKI 150
Query: 387 IVTCGKSHLYFWTLE-GSSLNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSGNILVW 444
W++E G + +G + ++C++F+ + TG +W
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAE------IVCLSFNPQSTLVATGSMDTTAKLW 204
Query: 445 GKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFG 504
Y ++G H I +L G + G D ++ W +
Sbjct: 205 DIQNGEEVYTLRG-HSAEIISLSFNTSGDRIITGSFDHTVVVWDAD-------------- 249
Query: 505 PIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKSQFLTCGHD 564
+G I GH E+ + + S LT D
Sbjct: 250 ---------------------------TGRKVNILIGHCAEISSASFNWDCSLILTGSMD 282
Query: 565 KHATLWDAVGHRPVWDKI-IEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHT 623
K LWDA + V +D S F +G ++A + G +F T+ +
Sbjct: 283 KTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLE 342
Query: 624 DGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKC----SGHSSFITHLD 679
++S + ++P GN L GS D I+ + G+C GH+ I
Sbjct: 343 GHEGEISKISFNPQGNHLLTGSSDKTARIWD--------AQTGQCLQVLEGHTDEIFSCA 394
Query: 680 WSVNSQFLVSNSGDYEILYW 699
++ +++ S D W
Sbjct: 395 FNYKGNIVITGSKDNTCRIW 414
Score = 39.3 bits (90), Expect = 0.015
Identities = 60/319 (18%), Positives = 112/319 (35%), Gaps = 69/319 (21%)
Query: 256 LYNVEEQLQRH-YAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLN 314
L++VE H + GH ++ CL+ +P +ATG + T+K +WD
Sbjct: 161 LWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAK----------LWDIQNGE 210
Query: 315 TLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAV 374
++ + + I+ S + G + + S DH + VWD K+ + +
Sbjct: 211 EVYTLR----GHSAEIISLSFNTSGDRI--ITGSFDHTVVVWDADTGRKVNILIGHCAEI 264
Query: 375 FAADFHPTDTNIIVT--CGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDT 432
+A F+ D ++I+T K+ + G + G ++ +L F G
Sbjct: 265 SSASFN-WDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDE------ILDSCFDYTGKL 317
Query: 433 I-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNY 491
I T + G ++ T + ++G HEG I + G + G D+ W
Sbjct: 318 IATASADGTARIFSAATRKCIAKLEG-HEGEISKISFNPQGNHLLTGSSDKTARIWDAQ- 375
Query: 492 QKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQGHTDELWGLAI 551
+G + +GHTDE++ A
Sbjct: 376 ----------------------------------------TGQCLQVLEGHTDEIFSCAF 395
Query: 552 HASKSQFLTCGHDKHATLW 570
+ + +T D +W
Sbjct: 396 NYKGNIVITGSKDNTCRIW 414
>gi|124028512 WD40-repeat protein upregulated in HCC isoform b [Homo
sapiens]
Length = 620
Score = 59.7 bits (143), Expect = 1e-08
Identities = 123/642 (19%), Positives = 242/642 (37%), Gaps = 77/642 (11%)
Query: 215 ELPTKRLKLEWVYGYRGRDCRNNLYLLPTG--------ETVYFIASVVVLYNVEEQLQRH 266
E L+L+ V G+ G +PTG +Y + V++ + + Q
Sbjct: 8 EAQVAELELDAVIGFNGH--------VPTGLKCHPDQEHMIYPLGCTVLIQAINTKEQNF 59
Query: 267 YAGHNDDVKCLAVHPDRITIATGQVA--GTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFF 324
GH ++V CLA+ IA+GQV G D + +WD L +
Sbjct: 60 LQGHGNNVSCLAISRSGEYIASGQVTFMGFKAD-------IILWDYKNRELL--ARLSLH 110
Query: 325 DRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAAD---FHP 381
+ +AFS ++ L ++ +D + VW K + + + V A F
Sbjct: 111 KGKIEALAFSPND--LYLVSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSR 168
Query: 382 TDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSGN 440
+ +T G + W L+ + + + + V+ + ++ G ++G+
Sbjct: 169 CRDEMFMTAGNGTIRVWELDLPNRKIWPTECQTGQLKRIVMSIGVDDDDSFFYLGTTTGD 228
Query: 441 ILVWGKGTNRISYA--VQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTE 498
IL T ++ + G+ A+ L+ G L+ G G + S Y+ ++K +
Sbjct: 229 ILKMNPRTKLLTDVGPAKDKFSLGVSAIRCLKMGGLLVGSGAGLLVFCKSPGYKPIKKIQ 288
Query: 499 IPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDF--TPITQGHTDELWGLAIHASKS 556
+ Q G G+G L+GT + + + + + DF T I H D + + +
Sbjct: 289 L--QGGITSITLRGEGHQFLVGTEESHIYRVSFT-DFKETLIATCHFDAVEDIVFPFGTA 345
Query: 557 Q-FLTCGHDKHATLWDAVGHRPVWDKIIED-PAQSSGFHPSGSVVAVGTLTGRWFVFDTE 614
+ F TC K +W +R + + + F G + G+ F E
Sbjct: 346 ELFATCA-KKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPE 404
Query: 615 TKDLVTVHTDGNE-QLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSS 673
T L+ V + + ++ + + D + G + + ++ + +K K H S
Sbjct: 405 TGRLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALK--EHKS 462
Query: 674 FITHLDWSVNSQFLVSNSGDYEILYW----------------VPSACK-----QVVSVET 712
++ + N++ V+ S D + W C Q+++ T
Sbjct: 463 SVSCIRVKRNNEECVTASTDGTCIIWDLVRLRRNQMILANTLFQCVCYHPEEFQIITSGT 522
Query: 713 TRDIE-WATYTCTLGFHVFGVWPEGSDGTDINAVCRAHEKKLLSTGDDFGKVHLFSYPCS 771
R I W + T+ + EGS IN + E TG + V ++ Y
Sbjct: 523 DRKIAYWEVFDGTVIREL-----EGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEG 577
Query: 772 QFRAPSHIYGGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWR 813
+ +H+ GHS ++T + + +++S D +I++W+
Sbjct: 578 EV---THVGVGHSGNITRIRISPGNQYIVSVSA-DGAILRWK 615
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 56.6 bits (135), Expect = 9e-08
Identities = 58/289 (20%), Positives = 109/289 (37%), Gaps = 22/289 (7%)
Query: 421 VLCVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGG 479
V CV FS N + +G ++VW +Y G H+ + + G L++ G
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTG-HKDAVTCVNFSPSGHLLASGS 80
Query: 480 KDRKLISWSGNYQKLRKTEIPEQFGPIRTV---AEGKGDVILIGTTRNFVLQGTLSGDFT 536
+D+ + W N K T +R+V ++G+ + + + T F
Sbjct: 81 RDKTVRIWVPNV-KGESTVFRAHTATVRSVHFCSDGQS-FVTASDDKTVKVWATHRQKFL 138
Query: 537 PITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGF---- 592
H + + ++ DK LWD + + + GF
Sbjct: 139 FSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSR-----ECVHSYCEHGGFVTYV 193
Query: 593 --HPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCI 650
HPSG+ +A + V+D T L+ + + ++ + + P GN+L S D+ +
Sbjct: 194 DFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTL 253
Query: 651 YIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW 699
I + + YT GH T + +S ++ S D +++ W
Sbjct: 254 KILDLMEGRLLYT----LHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 50.4 bits (119), Expect = 6e-06
Identities = 77/383 (20%), Positives = 141/383 (36%), Gaps = 37/383 (9%)
Query: 260 EEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVI 319
+ L+RH+ GH D V C+ +I T Q+A S D + H++ T H
Sbjct: 8 DPSLERHFKGHRDAVTCV-----DFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGH-- 60
Query: 320 GIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADF 379
AVTC+ FS S +L A S D + +W + + + V + F
Sbjct: 61 -----KDAVTCVNFSPSG---HLLA-SGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHF 111
Query: 380 HPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSG 439
+ + + W + ++++ LF + +V C FS +G I S
Sbjct: 112 CSDGQSFVTASDDKTVKVW-----ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDD 166
Query: 440 -NILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTE 498
+ +W K + ++ H G + + GT ++ G D + W +L +
Sbjct: 167 KTVKLWDKSSRECVHS-YCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY 225
Query: 499 IPEQFGPIRTVAEGKGDVILIGTTRNFV-LQGTLSGDFTPITQGHTDELWGLAIHASKSQ 557
G+ ++ ++ + + + + G GH +A +
Sbjct: 226 QLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEY 285
Query: 558 FLTCGHDKHATLW----DAVGHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDT 613
F + G D+ +W D V H V K+ PA + S + V L R + +
Sbjct: 286 FASGGSDEQVMVWKSNFDIVDHGEV-TKVPRPPATLAS---SMGNLTVSILEQRLTLTED 341
Query: 614 ETKDLVTVHTDGNEQLSVMRYSP 636
+ K + N+QL + R +P
Sbjct: 342 KLKQCLE-----NQQLIMQRATP 359
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/214 (23%), Positives = 81/214 (37%), Gaps = 43/214 (20%)
Query: 627 EQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQF 686
+ ++ + +S + LA GS D+C+ ++ + R Y + +GH +T +++S +
Sbjct: 20 DAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAY----RFTGHKDAVTCVNFSPSGHL 75
Query: 687 LVSNSGDYEILYWVPSA-------------------CKQVVSVETTRDIE----WATYTC 723
L S S D + WVP+ C S T D + WAT+
Sbjct: 76 LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQ 135
Query: 724 TLGFHVFGVWPEGSDGTDINAVCRAH---EKKLLSTGDDFGKVHLFSYPCSQFRAPSHIY 780
F S IN V A + +L+ + D V L+ R H Y
Sbjct: 136 KFLF---------SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD---KSSRECVHSY 183
Query: 781 GGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRV 814
H VT VDF I+ G D ++ W V
Sbjct: 184 CEHGGFVTYVDF-HPSGTCIAAAGMDNTVKVWDV 216
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 56.6 bits (135), Expect = 9e-08
Identities = 58/289 (20%), Positives = 109/289 (37%), Gaps = 22/289 (7%)
Query: 421 VLCVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGG 479
V CV FS N + +G ++VW +Y G H+ + + G L++ G
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTG-HKDAVTCVNFSPSGHLLASGS 80
Query: 480 KDRKLISWSGNYQKLRKTEIPEQFGPIRTV---AEGKGDVILIGTTRNFVLQGTLSGDFT 536
+D+ + W N K T +R+V ++G+ + + + T F
Sbjct: 81 RDKTVRIWVPNV-KGESTVFRAHTATVRSVHFCSDGQS-FVTASDDKTVKVWATHRQKFL 138
Query: 537 PITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQSSGF---- 592
H + + ++ DK LWD + + + GF
Sbjct: 139 FSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSR-----ECVHSYCEHGGFVTYV 193
Query: 593 --HPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCI 650
HPSG+ +A + V+D T L+ + + ++ + + P GN+L S D+ +
Sbjct: 194 DFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTL 253
Query: 651 YIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW 699
I + + YT GH T + +S ++ S D +++ W
Sbjct: 254 KILDLMEGRLLYT----LHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 49.3 bits (116), Expect = 1e-05
Identities = 67/334 (20%), Positives = 122/334 (36%), Gaps = 29/334 (8%)
Query: 260 EEQLQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVI 319
+ L+RH+ GH D V C+ +I T Q+A S D + H++ T H
Sbjct: 8 DPSLERHFKGHRDAVTCV-----DFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGH-- 60
Query: 320 GIGFFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADF 379
AVTC+ FS S +L A S D + +W + + + V + F
Sbjct: 61 -----KDAVTCVNFSPSG---HLLA-SGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHF 111
Query: 380 HPTDTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSG 439
+ + + W + ++++ LF + +V C FS +G I S
Sbjct: 112 CSDGQSFVTASDDKTVKVW-----ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDD 166
Query: 440 -NILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTE 498
+ +W K + ++ H G + + GT ++ G D + W +L +
Sbjct: 167 KTVKLWDKSSRECVHS-YCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY 225
Query: 499 IPEQFGPIRTVAEGKGDVILIGTTRNFV-LQGTLSGDFTPITQGHTDELWGLAIHASKSQ 557
G+ ++ ++ + + + + G GH +A +
Sbjct: 226 QLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEY 285
Query: 558 FLTCGHDKHATLW----DAVGHRPVWDKIIEDPA 587
F + G D+ +W D V H V K+ PA
Sbjct: 286 FASGGSDEQVMVWKSNFDIVDHGEV-TKVPRPPA 318
Score = 48.5 bits (114), Expect = 2e-05
Identities = 52/229 (22%), Positives = 86/229 (37%), Gaps = 17/229 (7%)
Query: 289 GQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVDDS 348
GQ T+ D K V++W T + + V C FS V S
Sbjct: 115 GQSFVTASDDKT----VKVW--ATHRQKFLFSLSQHINWVRCAKFSPDGR----LIVSAS 164
Query: 349 NDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLNKK 408
+D + +WD E + V DFHP+ T I + + W + L
Sbjct: 165 DDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRL--- 221
Query: 409 QGLFEKQEKPKFVLCVTFSENGD-TITGDSSGNILVWGKGTNRISYAVQGAHEGGIFALC 467
L Q V ++F +G+ IT S + + R+ Y + G H+G +
Sbjct: 222 --LQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHG-HQGPATTVA 278
Query: 468 MLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDV 516
R G + GG D +++ W N+ + E+ + P T+A G++
Sbjct: 279 FSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLASSMGNL 327
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/214 (23%), Positives = 81/214 (37%), Gaps = 43/214 (20%)
Query: 627 EQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQF 686
+ ++ + +S + LA GS D+C+ ++ + R Y + +GH +T +++S +
Sbjct: 20 DAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAY----RFTGHKDAVTCVNFSPSGHL 75
Query: 687 LVSNSGDYEILYWVPSA-------------------CKQVVSVETTRDIE----WATYTC 723
L S S D + WVP+ C S T D + WAT+
Sbjct: 76 LASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQ 135
Query: 724 TLGFHVFGVWPEGSDGTDINAVCRAH---EKKLLSTGDDFGKVHLFSYPCSQFRAPSHIY 780
F S IN V A + +L+ + D V L+ R H Y
Sbjct: 136 KFLF---------SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD---KSSRECVHSY 183
Query: 781 GGHSSHVTNVDFLCEDSHLISTGGKDTSIMQWRV 814
H VT VDF I+ G D ++ W V
Sbjct: 184 CEHGGFVTYVDF-HPSGTCIAAAGMDNTVKVWDV 216
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 56.2 bits (134), Expect = 1e-07
Identities = 49/209 (23%), Positives = 84/209 (40%), Gaps = 17/209 (8%)
Query: 287 ATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVTCIAFSKSNGGTNLCAVD 346
A GQ T+ + K +++W L+ + V C FS C
Sbjct: 112 ADGQFLATASEDKS----IKVWSMYRQRFLY--SLYRHTHWVRCAKFSPDGRLIVSC--- 162
Query: 347 DSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSSLN 406
S D + +WD ++ + + S DF+P+ T I + W + + L
Sbjct: 163 -SEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKL- 220
Query: 407 KKQGLFEKQEKPKFVLCVTFSENGD-TITGDSSGNILVWGKGTNRISYAVQGAHEGGIFA 465
L Q V C++F +G+ IT S G + + R+ Y +QG H G +F
Sbjct: 221 ----LQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQG-HTGPVFT 275
Query: 466 LCMLRDGTLVSGGGKDRKLISWSGNYQKL 494
+ + G L + GG D +++ W N+ +L
Sbjct: 276 VSFSKGGELFASGGADTQVLLWRTNFDEL 304
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/286 (18%), Positives = 110/286 (38%), Gaps = 16/286 (5%)
Query: 421 VLCVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGG 479
+ + S NG + T +++W + +Y G H+ + ++ G L++
Sbjct: 21 ITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVG-HKDVVTSVQFSPHGNLLASAS 79
Query: 480 KDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTT---RNFVLQGTLSGDFT 536
+DR + W + ++ + +E P+R+V + D + T ++ + F
Sbjct: 80 RDRTVRLWIPD-KRGKFSEFKAHTAPVRSV-DFSADGQFLATASEDKSIKVWSMYRQRFL 137
Query: 537 PITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDP---AQSSGFH 593
HT + ++C DK +WD + V + D A F+
Sbjct: 138 YSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNN--FSDSVGFANFVDFN 195
Query: 594 PSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIY 653
PSG+ +A V+D L+ + + ++ + + P GN+L S D + I
Sbjct: 196 PSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKIL 255
Query: 654 GVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW 699
+ + YT GH+ + + +S + S D ++L W
Sbjct: 256 DLLEGRLIYT----LQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297
Score = 45.1 bits (105), Expect = 3e-04
Identities = 66/310 (21%), Positives = 108/310 (34%), Gaps = 24/310 (7%)
Query: 263 LQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIG 322
L+R++ GH + L + P+ +AT T PH R + V G
Sbjct: 10 LERYFKGHKAAITSLDLSPNGKQLATASW-DTFLMLWNFKPHARAYRYV----------G 58
Query: 323 FFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPT 382
D VT + FS NL A S D + +W K K ++ K V + DF
Sbjct: 59 HKD-VVTSVQFSPHG---NLLA-SASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSAD 113
Query: 383 DTNIIVTCGKSHLYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSENGDTITGDSSGNIL 442
+ + W S+ +++ L+ +V C FS +G I S +
Sbjct: 114 GQFLATASEDKSIKVW-----SMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTI 168
Query: 443 VWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQ 502
TN+ G + GT ++ G D+ + W KL +
Sbjct: 169 KIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQ-HYQVH 227
Query: 503 FGPIRTVAEGKGDVILIGTTRNFVLQ--GTLSGDFTPITQGHTDELWGLAIHASKSQFLT 560
G + ++ LI + + L+ L G QGHT ++ ++ F +
Sbjct: 228 SGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFAS 287
Query: 561 CGHDKHATLW 570
G D LW
Sbjct: 288 GGADTQVLLW 297
Score = 37.7 bits (86), Expect = 0.043
Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
Query: 635 SPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDY 694
SP+G LA S D + ++ + R Y VG H +T + +S + L S S D
Sbjct: 27 SPNGKQLATASWDTFLMLWNFKPHARAYRYVG----HKDVVTSVQFSPHGNLLASASRDR 82
Query: 695 EILYWVP 701
+ W+P
Sbjct: 83 TVRLWIP 89
>gi|145279222 WD repeat domain 66 [Homo sapiens]
Length = 1149
Score = 55.8 bits (133), Expect = 2e-07
Identities = 106/530 (20%), Positives = 190/530 (35%), Gaps = 99/530 (18%)
Query: 217 PTKRLKLEWVYGYRG-------RDCRNNLYLLPTGETVYFIASVVVLYNVEEQLQRHYAG 269
P L + W +G+ R+ R + L Y A ++YNV Q H G
Sbjct: 245 PVYPLTMTWSFGWNSSLPVYYIREERQRVLL-------YVCAHTAIIYNVFRNNQYHLQG 297
Query: 270 HNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFFDRAVT 329
H + + CL V DR IAT K V IWDS T +H I FD
Sbjct: 298 HANIISCLCVSEDRRWIATAD--------KGPDCLVIIWDSFTGIPVHTI----FDSCPE 345
Query: 330 ---CIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAAD----FHPT 382
+A + ++ L + D+ + +W W + + F+PT
Sbjct: 346 GNGIMAMAMTHDAKYLATISDAEVQKVCIWKWTLAVETPACTLELPTEYGVQNYVTFNPT 405
Query: 383 DTNIIVTCGKSH--LYFWTLEGSSLNKKQGLFEKQEKPKFVLCVTFSEN------GDTIT 434
+ +V+ K+ Y W E +L L ++ K V FS++ ++
Sbjct: 406 NNKELVSNSKTRAIYYAWYEERDTLAHSAPLLTEKTFNKLV--GKFSQSIFHLNLTQILS 463
Query: 435 GDSSGNILVW------GKGTNRISY------AVQGAHEGGIFALCMLRDGTLVSGGGKDR 482
G ++VW + + + + + GI L + D +V+G K
Sbjct: 464 ATMEGKLVVWDIHRPPSSASTFLGFPYIKPCKLVHLQKEGITVLTTI-DSYIVTGDIKGN 522
Query: 483 --------KLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGD 534
+++W Y L+ G IRT++ K N+ TL GD
Sbjct: 523 IKFYDHTLSIVNW---YSHLK-------LGAIRTLSFSKTPATPPTEKSNYPPDCTLKGD 572
Query: 535 FTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDAVGHRPVWDKIIEDPAQ---SSG 591
+ F+ D A ++ +K+ +P +
Sbjct: 573 LFVL-----------------RNFIIGTSD--AAVYHLTTDGTKLEKLFVEPKDAICAIS 613
Query: 592 FHPSGSVVAVGTLTGRWFVFDTETKD-LVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCI 650
HP ++A+G++ G V++ E K L + + + + Y+P+G L G + +
Sbjct: 614 CHPYQPLIAIGSICGMIKVWNYENKQYLFSRVFEKGLGVQSLTYNPEGALLGAGFTEGTV 673
Query: 651 YIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYWV 700
YI + K S S +TH+ +S +SQ++ + + + ++
Sbjct: 674 YILDAMSLENESPEPFKYSRTS--VTHISFSHDSQYMATADRSFTVAVYM 721
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 53.9 bits (128), Expect = 6e-07
Identities = 40/166 (24%), Positives = 72/166 (43%), Gaps = 7/166 (4%)
Query: 536 TPITQGHTDELWGLAIHASKSQFLTCGHDKHATLW--DAVGHRPVWDKIIEDPAQSSGFH 593
T + QGH +W L I F + HD+ A LW D ++ + D FH
Sbjct: 377 TVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLAD-VDCVKFH 435
Query: 594 PSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIY 653
P+ + +A G+ ++ + + V + T + + +SP+G +LA D + ++
Sbjct: 436 PNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLW 495
Query: 654 GVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW 699
++ T + GH+ IT L +S +S + S S D + W
Sbjct: 496 DLASG----TLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVW 537
Score = 47.4 bits (111), Expect = 5e-05
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 23/178 (12%)
Query: 532 SGDFTPITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDA---------VGHR-PVWDK 581
+G I +GH ++ A S L+C D WD GH PVWD
Sbjct: 331 AGTEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDL 390
Query: 582 IIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFL 641
D + S + SGS T R + FD + ++ + +++ P+ N+L
Sbjct: 391 ---DISPYSLYFASGS----HDRTARLWSFDRTYP--LRIYAGHLADVDCVKFHPNSNYL 441
Query: 642 AIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLVSNSGDYEILYW 699
A GS D + ++ + ++ V +GH + L +S N ++L S D + W
Sbjct: 442 ATGSTDKTVRLW----SAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLW 495
Score = 39.3 bits (90), Expect = 0.015
Identities = 36/168 (21%), Positives = 64/168 (38%), Gaps = 24/168 (14%)
Query: 538 ITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDA---------VGHRPVWDKIIEDPAQ 588
I GH ++ + H + + T DK LW A GHR P
Sbjct: 421 IYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHR--------GPVL 472
Query: 589 SSGFHPSGSVVAVGTLTGRWFVFDTETKDLVTVHTDGNEQLSVMRYSPDGNFLAIGSHDN 648
S F P+G +A R ++D + L + ++ + +SPD +A S DN
Sbjct: 473 SLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDN 532
Query: 649 CIYIYGVSD-------NGRKYTRVGKCSGHSSFITHLDWSVNSQFLVS 689
+ ++ + + +G VG +G S + + + + LV+
Sbjct: 533 SVRVWDIRNTYCSAPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVT 580
Score = 36.2 bits (82), Expect = 0.13
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 17/125 (13%)
Query: 265 RHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIGFF 324
R YAGH DV C+ HP+ +ATG T VR+W + N++ + F
Sbjct: 420 RIYAGHLADVDCVKFHPNSNYLATGSTDKT----------VRLWSAQQGNSVRL----FT 465
Query: 325 DRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDT 384
++ + S G L + + D L +WD +++ + + + F P D+
Sbjct: 466 GHRGPVLSLAFSPNGKYLASAGE--DQRLKLWDLASGTLYKELRGHTDNITSLTFSP-DS 522
Query: 385 NIIVT 389
+I +
Sbjct: 523 GLIAS 527
Score = 30.4 bits (67), Expect = 6.9
Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 423 CVTFSENGDTI-TGDSSGNILVWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKD 481
CV F N + + TG + + +W S + H G + +L +G ++ G+D
Sbjct: 431 CVKFHPNSNYLATGSTDKTVRLWSAQQGN-SVRLFTGHRGPVLSLAFSPNGKYLASAGED 489
Query: 482 RKLISW---SGN-YQKLR 495
++L W SG Y++LR
Sbjct: 490 QRLKLWDLASGTLYKELR 507
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 53.5 bits (127), Expect = 8e-07
Identities = 59/291 (20%), Positives = 112/291 (38%), Gaps = 60/291 (20%)
Query: 419 KFVLCVTFSENGDTITGDSSGNIL-VWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSG 477
K V V FS NG+ + S+ ++ +WG + + G H+ GI + D L+
Sbjct: 46 KAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISG-HKLGISDVAWSSDSNLLVS 104
Query: 478 GGKDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTP 537
D+ L W + K KT
Sbjct: 105 ASDDKTLKIWDVSSGKCLKT---------------------------------------- 124
Query: 538 ITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDA-VGHRPVWDKIIEDPAQSSGFHPSG 596
+GH++ ++ + + ++ D+ +WD G DP + F+ G
Sbjct: 125 -LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDG 183
Query: 597 SVVAVGTLTGRWFVFDTETKD-LVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGV 655
S++ + G ++DT + L T+ D N +S +++SP+G ++ + DN + ++
Sbjct: 184 SLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY 243
Query: 656 SDNGRKYTRVGKC----SGHSS--FITHLDWSV-NSQFLVSNSGDYEILYW 699
S GKC +GH + + ++SV +++VS S D + W
Sbjct: 244 SK--------GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIW 286
Score = 44.7 bits (104), Expect = 4e-04
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 4/77 (5%)
Query: 629 LSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLV 688
+S +++SP+G +LA S D I I+G D + T SGH I+ + WS +S LV
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKT----ISGHKLGISDVAWSSDSNLLV 103
Query: 689 SNSGDYEILYWVPSACK 705
S S D + W S+ K
Sbjct: 104 SASDDKTLKIWDVSSGK 120
Score = 38.1 bits (87), Expect = 0.033
Identities = 49/233 (21%), Positives = 84/233 (36%), Gaps = 12/233 (5%)
Query: 345 VDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSS 404
V S+D L +WD + L +K + VF +F+P I+ + W ++
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162
Query: 405 LNKKQGLFEKQEKPKFVLCVTFSENGDTITGDS-SGNILVWGKGTNRISYAVQGAHEGGI 463
K P V V F+ +G I S G +W + + + +
Sbjct: 163 CLK---TLPAHSDP--VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV 217
Query: 464 FALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKT---EIPEQFGPIRTVAEGKGDVILIG 520
+ +G + D L W + K KT E++ + G I+ G
Sbjct: 218 SFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSG 277
Query: 521 TTRNFVLQGTL-SGDFTPITQGHTDELWGLAIHASKSQFLTCG--HDKHATLW 570
+ N V L + + QGHTD + A H +++ + +DK LW
Sbjct: 278 SEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 53.5 bits (127), Expect = 8e-07
Identities = 59/291 (20%), Positives = 112/291 (38%), Gaps = 60/291 (20%)
Query: 419 KFVLCVTFSENGDTITGDSSGNIL-VWGKGTNRISYAVQGAHEGGIFALCMLRDGTLVSG 477
K V V FS NG+ + S+ ++ +WG + + G H+ GI + D L+
Sbjct: 46 KAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISG-HKLGISDVAWSSDSNLLVS 104
Query: 478 GGKDRKLISWSGNYQKLRKTEIPEQFGPIRTVAEGKGDVILIGTTRNFVLQGTLSGDFTP 537
D+ L W + K KT
Sbjct: 105 ASDDKTLKIWDVSSGKCLKT---------------------------------------- 124
Query: 538 ITQGHTDELWGLAIHASKSQFLTCGHDKHATLWDA-VGHRPVWDKIIEDPAQSSGFHPSG 596
+GH++ ++ + + ++ D+ +WD G DP + F+ G
Sbjct: 125 -LKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDG 183
Query: 597 SVVAVGTLTGRWFVFDTETKD-LVTVHTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGV 655
S++ + G ++DT + L T+ D N +S +++SP+G ++ + DN + ++
Sbjct: 184 SLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDY 243
Query: 656 SDNGRKYTRVGKC----SGHSS--FITHLDWSV-NSQFLVSNSGDYEILYW 699
S GKC +GH + + ++SV +++VS S D + W
Sbjct: 244 SK--------GKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIW 286
Score = 44.7 bits (104), Expect = 4e-04
Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 4/77 (5%)
Query: 629 LSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNSQFLV 688
+S +++SP+G +LA S D I I+G D + T SGH I+ + WS +S LV
Sbjct: 48 VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKT----ISGHKLGISDVAWSSDSNLLV 103
Query: 689 SNSGDYEILYWVPSACK 705
S S D + W S+ K
Sbjct: 104 SASDDKTLKIWDVSSGK 120
Score = 38.1 bits (87), Expect = 0.033
Identities = 49/233 (21%), Positives = 84/233 (36%), Gaps = 12/233 (5%)
Query: 345 VDDSNDHVLSVWDWQKEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHLYFWTLEGSS 404
V S+D L +WD + L +K + VF +F+P I+ + W ++
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGK 162
Query: 405 LNKKQGLFEKQEKPKFVLCVTFSENGDTITGDS-SGNILVWGKGTNRISYAVQGAHEGGI 463
K P V V F+ +G I S G +W + + + +
Sbjct: 163 CLK---TLPAHSDP--VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV 217
Query: 464 FALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKT---EIPEQFGPIRTVAEGKGDVILIG 520
+ +G + D L W + K KT E++ + G I+ G
Sbjct: 218 SFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSG 277
Query: 521 TTRNFVLQGTL-SGDFTPITQGHTDELWGLAIHASKSQFLTCG--HDKHATLW 570
+ N V L + + QGHTD + A H +++ + +DK LW
Sbjct: 278 SEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330
>gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens]
Length = 919
Score = 53.5 bits (127), Expect = 8e-07
Identities = 61/293 (20%), Positives = 104/293 (35%), Gaps = 33/293 (11%)
Query: 391 GKSHLYFWTLEGSS-LNKKQGLFEKQEKPKFVLCVTFSENGDTI-TGDSSGNILVWGKGT 448
G L W + S + K+QG F ++ + +S +G I TG G + VW
Sbjct: 351 GLGQLLVWEWQSESYVLKQQGHFNS------MVALAYSPDGQYIVTGGDDGKVKVWNT-L 403
Query: 449 NRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWS-GNYQKLRKTEIPEQFGPIR 507
+ + H G+ + G +V D + ++ Y+ R P
Sbjct: 404 SGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSC 463
Query: 508 TVAEGKGDVILIGTTRNFVL--QGTLSGDFTPITQGHTDELWGLAIHASKSQFLTCGHDK 565
+ G+++ G +F + +G + GH + GL + KS + DK
Sbjct: 464 VAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDK 523
Query: 566 HATLWDAV-GHRPVWDKIIEDPAQSSGFHPSGSVVAVGTLTGRWFVFDTETK-------- 616
LWD R + A + F P G+ +AV TL + +D E
Sbjct: 524 TVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEG 583
Query: 617 -----------DLVTV-HTDGNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSD 657
D +T H + + + YS DG+ + G + IY V +
Sbjct: 584 RHDLKTGRKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVRE 636
Score = 40.8 bits (94), Expect = 0.005
Identities = 107/513 (20%), Positives = 168/513 (32%), Gaps = 118/513 (23%)
Query: 263 LQRHYAGHNDDVKCLAVHPDRITIATGQVAGTSKDGKQLPPHVRIWDSVTLNTLHVIGIG 322
L + Y G D+ C+ D G SKD WD++ L G
Sbjct: 136 LDKTYFGPYDETTCIDWTDDSRCFVVG-----SKDMSTWVFGAERWDNLIYYALG----G 186
Query: 323 FFDRAVTCIAFSKSNGGTNLCAVDDSNDHVLSVWD---------------W--------Q 359
D V C F +SN +L S D VL +W W +
Sbjct: 187 HKDAIVAC--FFESN---SLDLYSLSQDGVLCMWQCDTPPEGLRLKPPAGWKADLLQREE 241
Query: 360 KEEKLADVKCSNEAVFAADFHPTDTNIIVTCGKSHL--YFWTLEG-------SSLNKKQ- 409
+EE+ D + E P + S L YF+ EG ++ +KK
Sbjct: 242 EEEEEEDQEGDRETTIRGKATPAEEEKTGKVKYSRLAKYFFNKEGDFNNLTAAAFHKKSH 301
Query: 410 --------GLFEKQEKPKF------------VLCVTFSENGDTITGDSSG--NILVWGKG 447
G+F E P+F + V + +GD I SG +LVW
Sbjct: 302 LLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQ 361
Query: 448 TNRISYAVQGAHEGGIFALCMLRDGTLVSGGGKDRKLISWSGNYQKLRKTEIPEQFGPIR 507
+ QG H + AL DG + GG D K+ W+
Sbjct: 362 SESYVLKQQG-HFNSMVALAYSPDGQYIVTGGDDGKVKVWN------------------- 401
Query: 508 TVAEGKGDVILIGTTRNFVLQGTLSGDFTPITQGHTDELWGLAIHASKSQFLTCGHDKHA 567
TLSG H+ + G+ A+ +T D
Sbjct: 402 ----------------------TLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTV 439
Query: 568 TLWDAVGHRPVWDKIIEDPAQSS--GFHPSGSVVAVGTLTG-RWFVFDTETKDLVTVHTD 624
+D +R P Q S SG +V+ G FV+ +T L+ V +
Sbjct: 440 RAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSG 499
Query: 625 GNEQLSVMRYSPDGNFLAIGSHDNCIYIYGVSDNGRKYTRVGKCSGHSSFITHLDWSVNS 684
+S + ++P + LA S D + ++ + D+ R + S + D +
Sbjct: 500 HEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPD---GA 556
Query: 685 QFLVSNSGDYEILYWVPSACKQVVSVETTRDIE 717
+ V+ +I +W P Q S+E D++
Sbjct: 557 ELAVATLNS-QITFWDPENAVQTGSIEGRHDLK 588
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,933,065
Number of Sequences: 37866
Number of extensions: 1575467
Number of successful extensions: 7270
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 236
Number of HSP's that attempted gapping in prelim test: 5783
Number of HSP's gapped (non-prelim): 1360
length of query: 815
length of database: 18,247,518
effective HSP length: 111
effective length of query: 704
effective length of database: 14,044,392
effective search space: 9887251968
effective search space used: 9887251968
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.