Guide to the Human Genome
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Name: CXCR4 Sequence: fasta or formatted (356aa) NCBI GI: 56790927
Description:

chemokine (C-X-C motif) receptor 4 isoform a

Referenced in:

Chemokines and Their Receptors
Viral Receptors

Other entries for this name:
alt prot [352aa] chemokine (C-X-C motif) receptor 4 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         22           1
 C cysteine            2.5          9           2
 D aspartate           3.7         13           2
 E glutamate           3.7         13           2
 F phenylalanine       6.5         23           2
 G glycine             5.1         18           2
 H histidine           3.1         11           1
 I isoleucine         10.1         36           3
 K lysine              5.6         20           2
 L leucine            11.8         42           3
 M methionine          1.7          6           1
 N asparagine          3.7         13           1
 P proline             3.4         12           1
 Q glutamine           2.2          8           1
 R arginine            3.1         11           1
 S serine              9.6         34           3
 T threonine           4.5         16           2
 V valine              7.3         26           3
 W tryptophan          1.7          6           1
 Y tyrosine            4.8         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   chemokine (C-X-C motif) receptor 4 isoform a 
CXCR4                 0.977   chemokine (C-X-C motif) receptor 4 isoform b 
CCR4                  0.302   chemokine (C-C motif) receptor 4 
CXCR3                 0.286   chemokine (C-X-C motif) receptor 3 isoform B 
CXCR3                 0.286   chemokine (C-X-C motif) receptor 3 isoform A 
CCR7                  0.279   chemokine (C-C motif) receptor 7 precursor 
CCR9                  0.275   chemokine (C-C motif) receptor 9 isoform A 
IL8RA                 0.275   interleukin 8 receptor alpha 
CCR9                  0.273   chemokine (C-C motif) receptor 9 isoform B 
IL8RB                 0.273   interleukin 8 receptor beta 
CX3CR1                0.266   chemokine (C-X3-C motif) receptor 1 
CXCR5                 0.264   Burkitt lymphoma receptor 1 isoform 1 
CXCR5                 0.264   Burkitt lymphoma receptor 1 isoform 2 
CCR8                  0.259   chemokine (C-C motif) receptor 8 
CCR6                  0.254   chemokine (C-C motif) receptor 6 
CCR6                  0.254   chemokine (C-C motif) receptor 6 
CCR2                  0.254   chemokine (C-C motif) receptor 2 isoform A 
CCR2                  0.251   chemokine (C-C motif) receptor 2 isoform B 
CXCR6                 0.249   G protein-coupled receptor TYMSTR 
CCBP2                 0.246   chemokine binding protein 2 
CCR3                  0.246   CC chemokine receptor 3 
CCR3                  0.246   CC chemokine receptor 3 
CCRL1                 0.244   chemokine (C-C motif) receptor-like 1 
CCRL1                 0.244   chemokine (C-C motif) receptor-like 1 
CCR5                  0.244   chemokine (C-C motif) receptor 5 
CCR5                  0.244   chemokine (C-C motif) receptor 5 
CCR1                  0.241   chemokine (C-C motif) receptor 1 
AGTR1                 0.234   angiotensin II receptor, type 1 
AGTR1                 0.234   angiotensin II receptor, type 1 
AGTR1                 0.234   angiotensin II receptor, type 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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