Search of human proteins with 56788349

Search of human proteins with 56788349

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56788349 THAP domain containing 7 isoform 1 [Homo sapiens]
         (309 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56788351 THAP domain containing 7 isoform 2 [Homo sapiens]         640   0.0  
gi|56788349 THAP domain containing 7 isoform 1 [Homo sapiens]         640   0.0  
gi|94536788 THAP domain containing 9 [Homo sapiens]                    82   5e-16
gi|13899259 THAP domain containing, apoptosis associated protein...    63   4e-10
gi|21389507 THAP domain containing 6 [Homo sapiens]                    62   6e-10
gi|22749337 THAP domain containing 8 [Homo sapiens]                    61   1e-09
gi|194440668 THAP domain containing 5 isoform 1 [Homo sapiens]         60   2e-09
gi|31982895 THAP domain containing 4 [Homo sapiens]                    60   3e-09
gi|42734379 THAP domain containing, apoptosis associated protein...    54   2e-07
gi|19923268 protein-kinase, interferon-inducible double stranded...    49   6e-06
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          49   7e-06
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          49   7e-06
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          49   7e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     46   5e-05
gi|8922446 THAP domain containing, apoptosis associated protein ...    44   2e-04
gi|11386183 WAS protein family, member 2 [Homo sapiens]                43   3e-04
gi|28329422 acute myelogenous leukemia 1 translocation 1 protein...    42   5e-04
gi|28329419 acute myelogenous leukemia 1 translocation 1 protein...    42   5e-04
gi|28329416 acute myelogenous leukemia 1 translocation 1 protein...    42   5e-04
gi|4757916 acute myelogenous leukemia 1 translocation 1 protein ...    42   5e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    42   5e-04
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    42   7e-04
gi|100913021 BCL2-like 12 isoform 3 [Homo sapiens]                     42   0.001
gi|163965366 nascent polypeptide-associated complex alpha subuni...    41   0.001
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    41   0.001
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    41   0.002
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    41   0.002
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    40   0.003
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    40   0.003
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    40   0.003

>gi|56788351 THAP domain containing 7 isoform 2 [Homo sapiens]
          Length = 309

 Score =  640 bits (1650), Expect = 0.0
 Identities = 309/309 (100%), Positives = 309/309 (100%)

Query: 1   MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60
           MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY
Sbjct: 1   MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60

Query: 61  IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRL 120
           IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRL
Sbjct: 61  IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRL 120

Query: 121 RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG 180
           RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG
Sbjct: 121 RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG 180

Query: 181 PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW 240
           PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW
Sbjct: 181 PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW 240

Query: 241 KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF 300
           KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF
Sbjct: 241 KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF 300

Query: 301 AMQLSSSMA 309
           AMQLSSSMA
Sbjct: 301 AMQLSSSMA 309


>gi|56788349 THAP domain containing 7 isoform 1 [Homo sapiens]
          Length = 309

 Score =  640 bits (1650), Expect = 0.0
 Identities = 309/309 (100%), Positives = 309/309 (100%)

Query: 1   MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60
           MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY
Sbjct: 1   MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60

Query: 61  IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRL 120
           IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRL
Sbjct: 61  IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRL 120

Query: 121 RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG 180
           RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG
Sbjct: 121 RRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLG 180

Query: 181 PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW 240
           PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW
Sbjct: 181 PLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLW 240

Query: 241 KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF 300
           KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF
Sbjct: 241 KRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDF 300

Query: 301 AMQLSSSMA 309
           AMQLSSSMA
Sbjct: 301 AMQLSSSMA 309


>gi|94536788 THAP domain containing 9 [Homo sapiens]
          Length = 903

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 47/107 (43%), Positives = 62/107 (57%), Gaps = 6/107 (5%)

Query: 1   MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60
           M R CSA GC TRDT  +R RG+SFH+ P  D  +R  W+    R+DP  + +W P    
Sbjct: 1   MTRSCSAVGCSTRDTVLSRERGLSFHQFP-TDTIQRSKWIRAVNRVDPRSKKIWIPGPGA 59

Query: 61  IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKG 107
           I  CSKHF+E  FE  GI    +LK+GAVP++  S  K+ +    KG
Sbjct: 60  I-LCSKHFQESDFESYGIR--RKLKKGAVPSV--SLYKIPQGVHLKG 101


>gi|13899259 THAP domain containing, apoptosis associated protein 2
           [Homo sapiens]
          Length = 228

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 44/124 (35%), Positives = 59/124 (47%), Gaps = 20/124 (16%)

Query: 1   MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60
           MP +C+AAGC T   +      ISFHR P  D  RR  W+   +R +           ++
Sbjct: 1   MPTNCAAAGCATTYNKHIN---ISFHRFPL-DPKRRKEWVRLVRRKN-------FVPGKH 49

Query: 61  IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFS-------KLRRTTKTKGHSYPPG 113
            + CSKHFE  CF+L G +   RLK  AVPTIF+  +       K R   K      P G
Sbjct: 50  TFLCSKHFEASCFDLTGQT--RRLKMDAVPTIFDFCTHIKSMKLKSRNLLKKNNSCSPAG 107

Query: 114 PAEV 117
           P+ +
Sbjct: 108 PSNL 111


>gi|21389507 THAP domain containing 6 [Homo sapiens]
          Length = 222

 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 32/95 (33%), Positives = 56/95 (58%), Gaps = 4/95 (4%)

Query: 1  MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60
          M + CSA GC +R    ++ +G++FH  P  +N +R  W+   +RLD +  G+W+P    
Sbjct: 1  MVKCCSAIGCASRCLPNSKLKGLTFHVFPTDENIKR-KWVLAMKRLDVNAAGIWEPKKGD 59

Query: 61 IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFES 95
          +  CS+HF++  F+    +   +LK G +P+IF+S
Sbjct: 60 V-LCSRHFKKTDFDRSAPN--IKLKPGVIPSIFDS 91


>gi|22749337 THAP domain containing 8 [Homo sapiens]
          Length = 274

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 76/280 (27%), Positives = 106/280 (37%), Gaps = 56/280 (20%)

Query: 1   MPRHCSAAGCCTRDTR-ETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASE 59
           MP++C A  C     R    NR +SF++ P KD PR   WL +       G   W P S 
Sbjct: 1   MPKYCRAPNCSNTAGRLGADNRPVSFYKFPLKDGPRLQAWLQH------MGCEHWVP-SC 53

Query: 60  YIYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSR 119
           + + CS+HF   CF+     G   L+  AVP+IF                   GP   S+
Sbjct: 54  HQHLCSEHFTPSCFQWRW--GVRYLRPDAVPSIFSR-----------------GPPAKSQ 94

Query: 120 LRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLL 179
            R         R    P SPPPP      P+ ++ A   +P S   RL          +L
Sbjct: 95  RRT--------RSTQKPVSPPPPLQKNT-PLPQSPA---IPVSGPVRLV---------VL 133

Query: 180 GPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAY-MLRLPPPAGAYIQNEHSYQVGSAL 238
           GP                   P+P   +P  P+      L P  GA  +     Q     
Sbjct: 134 GPTSGSPKTVATMLLTPLAPAPTPERSQPEVPAQQAQTGLGPVLGALQRRVRRLQ----- 188

Query: 239 LWKRRAEAALDALDKAQRQL--QACKRREQRLRLRLTKLQ 276
             + R +A L AL++  +QL  ++   R +R   RLT  Q
Sbjct: 189 RCQERHQAQLQALERLAQQLHGESLLARARRGLQRLTTAQ 228


>gi|194440668 THAP domain containing 5 isoform 1 [Homo sapiens]
          Length = 395

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 36/93 (38%), Positives = 48/93 (51%), Gaps = 9/93 (9%)

Query: 1  MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60
          MPR+C+A  C  R  R  ++R +SF+  P  D  R   WL N +R        W P S+Y
Sbjct: 1  MPRYCAAICCKNRRGRNNKDRKLSFYPFPLHDKERLEKWLKNMKR------DSWVP-SKY 53

Query: 61 IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIF 93
           + CS HF  D  ++    G   LK+ AVPTIF
Sbjct: 54 QFLCSDHFTPDSLDIRW--GIRYLKQTAVPTIF 84


>gi|31982895 THAP domain containing 4 [Homo sapiens]
          Length = 577

 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 65/248 (26%), Positives = 98/248 (39%), Gaps = 26/248 (10%)

Query: 5   CSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEYIYFC 64
           C+A  C  R  +  + R +SFHR P KD+ R   WL   QR +      W P ++Y + C
Sbjct: 5   CAAVNCSNRQGKGEK-RAVSFHRFPLKDSKRLIQWLKAVQRDN------WTP-TKYSFLC 56

Query: 65  SKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRLRRCR 124
           S+HF +D F       +  LK  AVP+IF    K +R     G +     ++ +   R  
Sbjct: 57  SEHFTKDSFSKRLEDQHRLLKPTAVPSIFHLTEK-KRGAGGHGRTRRKDASKATGGVRGH 115

Query: 125 KRCSEGRGPTTPFSPPPPADVTCFPVE----------EASAPATLPASPAGRLEPGLSSP 174
              + GRG    +SP    +    P            EA+  A   A+   + +  L   
Sbjct: 116 SSAATGRG-AAGWSPSSSGNPMAKPESRRLKQAALQGEATPRAAQEAASQEQAQQALERT 174

Query: 175 FSDLLGPL--GAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLR--LPPPAGA--YIQN 228
             D L  +  G+Q      +     E   S +E      S   +    PP +GA  +I +
Sbjct: 175 PGDGLATMVAGSQGKAEASATDAGDESATSSIEGGVTDKSGISMDDFTPPGSGACKFIGS 234

Query: 229 EHSYQVGS 236
            HSY   S
Sbjct: 235 LHSYSFSS 242


>gi|42734379 THAP domain containing, apoptosis associated protein 3
           [Homo sapiens]
          Length = 175

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 16/141 (11%)

Query: 1   MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60
           MP+ C+A  CC R +  +R + ++FHR P         W+ N       G+G + P  ++
Sbjct: 1   MPKSCAARQCCNRYS--SRRKQLTFHRFPFSRPELLKEWVLNI------GRGNFKP-KQH 51

Query: 61  IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIF---ESFSKLRRTTKTKGHSYPPGPAEV 117
              CS+HF  +CF   G      LK  AVPT+F   +   ++R  T           ++ 
Sbjct: 52  TVICSEHFRPECFSAFG--NRKNLKHNAVPTVFAFQDPTQQVRENTDPASERGNASSSQK 109

Query: 118 SRLRRCRKRC--SEGRGPTTP 136
            +   CR +     G G  +P
Sbjct: 110 EKTSPCRSQVLPEAGAGEDSP 130


>gi|19923268 protein-kinase, interferon-inducible double stranded
          RNA dependent inhibitor, repressor of (P58 repressor)
          [Homo sapiens]
          Length = 761

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 9/100 (9%)

Query: 1  MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60
          MP  C+A  C    TR++    ++F R P+ D  R   W+ NC+R D   +   D  +++
Sbjct: 1  MPNFCAAPNC----TRKSTQSDLAFFRFPR-DPARCQKWVENCRRADLEDKTP-DQLNKH 54

Query: 61 IYFCSKHFEEDCFELVGISGYHR-LKEGAVPTIFESFSKL 99
             C+KHFE     +   S Y   L++ A+PTIF+  S L
Sbjct: 55 YRLCAKHFETSM--ICRTSPYRTVLRDNAIPTIFDLTSHL 92


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 54/206 (26%), Positives = 83/206 (40%), Gaps = 32/206 (15%)

Query: 105 TKGHSYPPGPAE--VSRLRRCRKRCSEGRGPTTPFSPPPPADVTC--------FPVEEAS 154
           T+  + PP PA    + L +   +    + P  P  PPP    TC         P   A 
Sbjct: 454 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ 513

Query: 155 APATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAY 214
            P +  A+  G +  G S P   +     A  D     + P P R PSP EP  V   ++
Sbjct: 514 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP-EPTVVDTPSH 572

Query: 215 MLRLPPPAGAYIQNEHSYQ------------VGSALLWKRRAEAALDALDKAQRQLQACK 262
             +    A  Y   +  Y              GS L  KR      +A++KA+R+ +  K
Sbjct: 573 ASQ---SARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKRE-----EAIEKAKREAEQ-K 623

Query: 263 RREQRLRLRLTKLQQERAREKRAQAD 288
            RE+R R +  + ++ER RE+  +A+
Sbjct: 624 AREEREREKEKEKEREREREREREAE 649



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 15/102 (14%)

Query: 139 PPPPADVTCFPVEEASAPATLPASPAGRLEPGLS--SPFS--------DLLGPLGAQADE 188
           PP P  +        +    LPA  A +  P LS  SPFS          L PL + +  
Sbjct: 365 PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTH 424

Query: 189 AGCSAQPSP-----ERQPSPLEPRPVSPSAYMLRLPPPAGAY 225
              SA P P     + QP P  P           LPPP  ++
Sbjct: 425 HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH 466


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 54/206 (26%), Positives = 83/206 (40%), Gaps = 32/206 (15%)

Query: 105  TKGHSYPPGPAE--VSRLRRCRKRCSEGRGPTTPFSPPPPADVTC--------FPVEEAS 154
            T+  + PP PA    + L +   +    + P  P  PPP    TC         P   A 
Sbjct: 1008 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ 1067

Query: 155  APATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAY 214
             P +  A+  G +  G S P   +     A  D     + P P R PSP EP  V   ++
Sbjct: 1068 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP-EPTVVDTPSH 1126

Query: 215  MLRLPPPAGAYIQNEHSYQ------------VGSALLWKRRAEAALDALDKAQRQLQACK 262
              +    A  Y   +  Y              GS L  KR      +A++KA+R+ +  K
Sbjct: 1127 ASQ---SARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKRE-----EAIEKAKREAEQ-K 1177

Query: 263  RREQRLRLRLTKLQQERAREKRAQAD 288
             RE+R R +  + ++ER RE+  +A+
Sbjct: 1178 AREEREREKEKEKEREREREREREAE 1203



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 15/102 (14%)

Query: 139  PPPPADVTCFPVEEASAPATLPASPAGRLEPGLS--SPFS--------DLLGPLGAQADE 188
            PP P  +        +    LPA  A +  P LS  SPFS          L PL + +  
Sbjct: 919  PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTH 978

Query: 189  AGCSAQPSP-----ERQPSPLEPRPVSPSAYMLRLPPPAGAY 225
               SA P P     + QP P  P           LPPP  ++
Sbjct: 979  HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH 1020


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 54/206 (26%), Positives = 83/206 (40%), Gaps = 32/206 (15%)

Query: 105  TKGHSYPPGPAE--VSRLRRCRKRCSEGRGPTTPFSPPPPADVTC--------FPVEEAS 154
            T+  + PP PA    + L +   +    + P  P  PPP    TC         P   A 
Sbjct: 1008 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ 1067

Query: 155  APATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAY 214
             P +  A+  G +  G S P   +     A  D     + P P R PSP EP  V   ++
Sbjct: 1068 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP-EPTVVDTPSH 1126

Query: 215  MLRLPPPAGAYIQNEHSYQ------------VGSALLWKRRAEAALDALDKAQRQLQACK 262
              +    A  Y   +  Y              GS L  KR      +A++KA+R+ +  K
Sbjct: 1127 ASQ---SARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKRE-----EAIEKAKREAEQ-K 1177

Query: 263  RREQRLRLRLTKLQQERAREKRAQAD 288
             RE+R R +  + ++ER RE+  +A+
Sbjct: 1178 AREEREREKEKEKEREREREREREAE 1203



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 29/102 (28%), Positives = 37/102 (36%), Gaps = 15/102 (14%)

Query: 139  PPPPADVTCFPVEEASAPATLPASPAGRLEPGLS--SPFS--------DLLGPLGAQADE 188
            PP P  +        +    LPA  A +  P LS  SPFS          L PL + +  
Sbjct: 919  PPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTH 978

Query: 189  AGCSAQPSP-----ERQPSPLEPRPVSPSAYMLRLPPPAGAY 225
               SA P P     + QP P  P           LPPP  ++
Sbjct: 979  HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH 1020


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 39/130 (30%), Positives = 48/130 (36%), Gaps = 16/130 (12%)

Query: 95  SFSKLRRTTKTKGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEAS 154
           S+    R    +  + PP P    R        +    P TP  PPPPA V       A 
Sbjct: 92  SYRNAARVQPPRRGATPPAPPRAPR--GAPAAAAAAAPPPTPAPPPPPAPVAA--AAPAR 147

Query: 155 APATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAY 214
           AP    A+      PG + P        G +A  A   A P     P+P  P  V+P A 
Sbjct: 148 APRAAAAAATAPPSPGPAQP--------GPRAQRAAPLAAP----PPAPAAPPAVAPPAG 195

Query: 215 MLRLPPPAGA 224
             R PPPA A
Sbjct: 196 PRRAPPPAVA 205


>gi|8922446 THAP domain containing, apoptosis associated protein 1
          isoform 1 [Homo sapiens]
          Length = 213

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 12/93 (12%)

Query: 1  MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60
          M + CSA GC     R  +++ +SFH+ P         W A  +R +      + P ++Y
Sbjct: 1  MVQSCSAYGC---KNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKN------FKP-TKY 50

Query: 61 IYFCSKHFEEDCFELVGISGYHRLKEGAVPTIF 93
             CS+HF  DCF+         LKE AVPTIF
Sbjct: 51 SSICSEHFTPDCFKRE--CNNKLLKENAVPTIF 81



 Score = 35.4 bits (80), Expect = 0.065
 Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 6/89 (6%)

Query: 194 QPSPERQPSPLEPRPVSP--SAYMLRLPP---PAGAYIQNEHSYQVGSALLWKRRAEAAL 248
           +P  +  P PL P PVS   +A  L +PP   P    +  +H+Y V   +  ++R     
Sbjct: 95  EPQEQLPPPPLPP-PVSQVDAAIGLLMPPLQTPVNLSVFCDHNYTVEDTMHQRKRIHQLE 153

Query: 249 DALDKAQRQLQACKRREQRLRLRLTKLQQ 277
             ++K +++L+  ++R +R   +L KL++
Sbjct: 154 QQVEKLRKKLKTAQQRCRRQERQLEKLKE 182


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 52/202 (25%), Positives = 69/202 (34%), Gaps = 43/202 (21%)

Query: 26  HRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEYIYFCSKHFEEDCFELVGISGYHRLK 85
           HR  KKDNP RG    N +++    +  W+          + F E   E +G SGY    
Sbjct: 178 HRKEKKDNPNRGN--VNPRKIKTRKEE-WEKMK-----MGQEFVESK-EKLGTSGYP--- 225

Query: 86  EGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFS----PPP 141
               PT+      +         SYPP P   S              P+  FS    PPP
Sbjct: 226 ----PTLVYQNGSIGCVENVDASSYPPPPQSDS-----------ASSPSPSFSEDNLPPP 270

Query: 142 PADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQP 201
           PA+ + +PV+            +  + P    P   L  P G           P P   P
Sbjct: 271 PAEFS-YPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPG-----------PKPGFAP 318

Query: 202 SPLEPRPVSPSAYMLRLPPPAG 223
            P  P P  P   +   PPP G
Sbjct: 319 PPAPPPPPPPMIGIPPPPPPVG 340



 Score = 35.4 bits (80), Expect = 0.065
 Identities = 39/150 (26%), Positives = 63/150 (42%), Gaps = 30/150 (20%)

Query: 135 TPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQ 194
           +P +PPPP+  +  P  + +AP   P  PA    P L  P   L  P G      G    
Sbjct: 343 SPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADY-PTLPPP--PLSQPTG------GAPPP 393

Query: 195 PSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLWKRRAEAALDALDKA 254
           P P   P P  P P + +     +PPP                L    + +++L A+  A
Sbjct: 394 PPPPPPPGP-PPPPFTGADGQPAIPPP----------------LSDTTKPKSSLPAVSDA 436

Query: 255 QRQLQACKRREQRLRLRLTKLQQERAREKR 284
           +  L +  R+  +LR    +++++R +EKR
Sbjct: 437 RSDLLSAIRQGFQLR----RVEEQREQEKR 462


>gi|28329422 acute myelogenous leukemia 1 translocation 1 protein
           isoform MTG8c [Homo sapiens]
          Length = 567

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 13/107 (12%)

Query: 190 GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLWKRRAEAALD 249
           G  +  S  RQ SP+ P PV+  A+   L  PA  Y+  E         +WK+  EA  +
Sbjct: 368 GGGSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEE---------IWKKAEEAVNE 418

Query: 250 ALDKAQRQLQ-ACKRREQRLRLRLTKLQQERAREKRAQADARQTLKE 295
              +A  +LQ A    E++    +T    ERA+ +R  A+A++   E
Sbjct: 419 VKRQAMTELQKAVSEAERKAHDMIT---TERAKMERTVAEAKRQAAE 462


>gi|28329419 acute myelogenous leukemia 1 translocation 1 protein
           isoform MTG8c [Homo sapiens]
          Length = 567

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 13/107 (12%)

Query: 190 GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLWKRRAEAALD 249
           G  +  S  RQ SP+ P PV+  A+   L  PA  Y+  E         +WK+  EA  +
Sbjct: 368 GGGSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEE---------IWKKAEEAVNE 418

Query: 250 ALDKAQRQLQ-ACKRREQRLRLRLTKLQQERAREKRAQADARQTLKE 295
              +A  +LQ A    E++    +T    ERA+ +R  A+A++   E
Sbjct: 419 VKRQAMTELQKAVSEAERKAHDMIT---TERAKMERTVAEAKRQAAE 462


>gi|28329416 acute myelogenous leukemia 1 translocation 1 protein
           isoform MTG8b [Homo sapiens]
          Length = 604

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 13/107 (12%)

Query: 190 GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLWKRRAEAALD 249
           G  +  S  RQ SP+ P PV+  A+   L  PA  Y+  E         +WK+  EA  +
Sbjct: 405 GGGSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEE---------IWKKAEEAVNE 455

Query: 250 ALDKAQRQLQ-ACKRREQRLRLRLTKLQQERAREKRAQADARQTLKE 295
              +A  +LQ A    E++    +T    ERA+ +R  A+A++   E
Sbjct: 456 VKRQAMTELQKAVSEAERKAHDMIT---TERAKMERTVAEAKRQAAE 499


>gi|4757916 acute myelogenous leukemia 1 translocation 1 protein
           isoform MTG8a [Homo sapiens]
          Length = 577

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 13/107 (12%)

Query: 190 GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLWKRRAEAALD 249
           G  +  S  RQ SP+ P PV+  A+   L  PA  Y+  E         +WK+  EA  +
Sbjct: 378 GGGSSSSHSRQQSPVNPDPVALDAHREFLHRPASGYVPEE---------IWKKAEEAVNE 428

Query: 250 ALDKAQRQLQ-ACKRREQRLRLRLTKLQQERAREKRAQADARQTLKE 295
              +A  +LQ A    E++    +T    ERA+ +R  A+A++   E
Sbjct: 429 VKRQAMTELQKAVSEAERKAHDMIT---TERAKMERTVAEAKRQAAE 472


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 33/96 (34%), Positives = 38/96 (39%), Gaps = 12/96 (12%)

Query: 135 TPFSPPPPADVTCFPVEEASA---PATLPASP---AGRLEPGLSSPFSDLLGPLGAQADE 188
           TP SPPP A     P EE+     P  LP SP   A RL P           P+    +E
Sbjct: 534 TPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE------SPMSPPPEE 587

Query: 189 AGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
           +  S  P   R   P E  P+SP      L PP  A
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 32/92 (34%), Positives = 38/92 (41%), Gaps = 12/92 (13%)

Query: 136 PFSPPPPADVTCFPVEEASA---PATLPASP---AGRLEPGLSSPFSDLLGPLGAQADEA 189
           P SPPP A     P EE+     P   P SP   A RL P    PF +   PL    +E+
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFP----PFEE--SPLSPPPEES 615

Query: 190 GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPP 221
             S  P   R   P E  P+SP      + PP
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 37/126 (29%), Positives = 42/126 (33%), Gaps = 21/126 (16%)

Query: 88   AVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVT- 146
            A P       +L      KG S P  P     L              TP SPPP A+ T 
Sbjct: 946  AAPPALSPLGELEYPFGAKGDSDPESPLAAPILE-------------TPISPPPEANCTD 992

Query: 147  CFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPL------GAQADEAGCSAQPSPERQ 200
              PV     P + P SP G   P L  P      PL         +  + CS    P   
Sbjct: 993  PEPVPPMILPPS-PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSV 1051

Query: 201  PSPLEP 206
            PSPL P
Sbjct: 1052 PSPLSP 1057



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 12/99 (12%)

Query: 135 TPFSPPPPADVTCFPVEEA--SAPATLPASPA--GRLEP-----GLSSPFSDLLGPLGAQ 185
           +P SPPP +     P+EE+  S P   P SPA    L P      LS PF +   PL   
Sbjct: 501 SPLSPPPESS-PFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE--SPLSPP 557

Query: 186 ADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
            +E   S  P   R   P E  P+SP      + PP  A
Sbjct: 558 PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 31/98 (31%), Positives = 37/98 (37%), Gaps = 13/98 (13%)

Query: 135 TPFSPPPPADVTCFPVEEASA---PATLPASP---AGRLEP-----GLSSPFSDLLGPLG 183
           +P SPPP A     P E++     P   P SP     RL P      LS P  +   PL 
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE--SPLS 672

Query: 184 AQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPP 221
              +E+  S  P   R   P E  P SP        PP
Sbjct: 673 PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP 710



 Score = 32.7 bits (73), Expect = 0.42
 Identities = 42/164 (25%), Positives = 54/164 (32%), Gaps = 50/164 (30%)

Query: 93  FESFSKLRRTTKTKGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEE 152
           FE++S   R  K +G     G    S   +    CS        FSPP P D    P +E
Sbjct: 340 FENYSLCHRCHKAQG-----GQTIRSVAEQHTPVCSR-------FSPPEPGDT---PTDE 384

Query: 153 ASA-----------------------PATLPASPAGR----LEPGLSSPFSDLL------ 179
             A                       P    A P G+    LEP L +P ++ +      
Sbjct: 385 PDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPP 444

Query: 180 --GPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPP 221
              PL    +E+  S  P   R   P E  P SP    L L  P
Sbjct: 445 EESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRP 488



 Score = 32.0 bits (71), Expect = 0.71
 Identities = 32/95 (33%), Positives = 37/95 (38%), Gaps = 9/95 (9%)

Query: 140  PPPADVTCFPVEEASAPATLPASPAGRLE------PGLSSPFSDLLGPLGAQADEAGCSA 193
            PPPA      +   + PA L  S  G L+      PG  SP  +L   L  Q      S 
Sbjct: 2116 PPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSP-GELFLKLPPQVPAQVPSQ 2174

Query: 194  QPSPERQPSPLEPR-PVSPSAYMLRLPPPAGAYIQ 227
             P       PLEPR P +P  Y    P P GA  Q
Sbjct: 2175 DPFGLAPAYPLEPRFPTAPPTYP-PYPSPTGAPAQ 2208



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 26/100 (26%), Positives = 35/100 (35%), Gaps = 31/100 (31%)

Query: 133  PTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCS 192
            P TP   PPP +  C     A  P +LP+ P  R+                        +
Sbjct: 2382 PLTPRPQPPPPESCC-----ALPPRSLPSDPFSRVP-----------------------A 2413

Query: 193  AQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSY 232
            +  S     SPL PRP+S  A+    P P     Q+   Y
Sbjct: 2414 SPQSQSSSQSPLTPRPLSAEAF---CPSPVTPRFQSPDPY 2450



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 38/121 (31%), Positives = 45/121 (37%), Gaps = 18/121 (14%)

Query: 114 PAEVSRLRRCRKRCSEGRGPT-TPFSPPPPADVTCFPVEEA------SAPATLPASPAGR 166
           P E SRL    +       P  +P SPPP   +   P+EE+        P   P S    
Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPH 742

Query: 167 LEPGLSSPFSDLLGP------LGAQADEAGCSAQP-SPERQPSPLEPRPVSPSAYMLRLP 219
           L P    P    L P      L  QA+E   S QP  P     P EP  +SP A    L 
Sbjct: 743 LSPRPEEPH---LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH-LSPQAEGPHLS 798

Query: 220 P 220
           P
Sbjct: 799 P 799



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 7/90 (7%)

Query: 133 PTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCS 192
           P  P   P P ++  FP      P   P+      EP LS P    L PL  +   +  S
Sbjct: 868 PEEPGQCPAPEELPLFP------PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSP-S 920

Query: 193 AQPSPERQPSPLEPRPVSPSAYMLRLPPPA 222
            +PS   Q  P +P P   S  +    PPA
Sbjct: 921 GEPSLSPQLMPPDPLPPPLSPIITAAAPPA 950



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 33/93 (35%), Positives = 40/93 (43%), Gaps = 11/93 (11%)

Query: 130  GRGPTT---PFSPPPPADVTCFPVEEASAPATLPASPAGRLEPG-LSSPFSDLLGPLGAQ 185
            G GP     P  P PP  ++  PV     P   P+SP     P  L SP S L  P  AQ
Sbjct: 4278 GAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL--PTEAQ 4335

Query: 186  ADEAGCSAQPSPERQPSPLEPRP--VSPSAYML 216
                  +   +P+ Q   LEP P  VSP+A  L
Sbjct: 4336 LPP---THPGTPKPQGPTLEPPPGRVSPAAAQL 4365



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 25/91 (27%), Positives = 35/91 (38%), Gaps = 13/91 (14%)

Query: 136 PFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQP 195
           P   P P ++   P  E    + +P  P    +P  S         L  Q++E   S +P
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH--------LSPQSEEPCLSPRP 846

Query: 196 -----SPERQPSPLEPRPVSPSAYMLRLPPP 221
                SPE +  PL PRP  P     + P P
Sbjct: 847 EESHLSPELEKPPLSPRPEKPPEEPGQCPAP 877



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 28/84 (33%), Positives = 32/84 (38%), Gaps = 14/84 (16%)

Query: 127  CSEGRGPTTPFSPPPPADVTCFPVEEAS------APATLPASPAGRLEPGLSSPFSDLLG 180
            C E   P  P +P PP  +    V E S      A A+ P S     EP L SP  +  G
Sbjct: 1182 CEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGS-----EPLLGSPDPEGGG 1236

Query: 181  PLGAQADEAGCSAQPSPERQPSPL 204
             L     E G S   SP R    L
Sbjct: 1237 SLSM---ELGVSTDVSPARDEGSL 1257


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 33/103 (32%), Positives = 41/103 (39%), Gaps = 12/103 (11%)

Query: 130 GRGPT-TPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPG---------LSSPFS-DL 178
           GRGP   P  PPPP      P      P+ + +  +G   PG           +PFS + 
Sbjct: 775 GRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEG 834

Query: 179 LGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPP 221
             P G  A+E G     +P   P P  PRP  P    L LP P
Sbjct: 835 AFPGGGAAEEEGVPRPRAPPEPPDPGAPRP-PPDPGPLPLPGP 876



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 33/105 (31%), Positives = 41/105 (39%), Gaps = 10/105 (9%)

Query: 128  SEGRGPTTPFS-PPPPADVTCFPVEEASAPAT--LPASP-AGRLEPGLS--SPFSDLLGP 181
            S   G T P    P P + T  P  E  AP T   P +P AGRL+ G    +P      P
Sbjct: 1093 SRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAP 1152

Query: 182  LGAQAD----EAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPA 222
             G        +AG      P+  P PL P P +    +   PP A
Sbjct: 1153 GGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRA 1197


>gi|100913021 BCL2-like 12 isoform 3 [Homo sapiens]
          Length = 333

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 35/100 (35%), Positives = 43/100 (43%), Gaps = 23/100 (23%)

Query: 111 PPGPAE------VSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPA 164
           PP PA+      +SRLRRC   CS GRG     SP                P +LP  P 
Sbjct: 118 PPSPAQEEPTDFLSRLRRCLP-CSLGRGAAPSESP---------------RPCSLPIRPC 161

Query: 165 GRLEPGLSSP-FSDLLGPLGAQADEAGCSAQPSPERQPSP 203
             LEPG ++P F  L+     Q  +    + PSPE Q  P
Sbjct: 162 YGLEPGPATPDFYALVAQRLEQLVQEQLKSPPSPELQGPP 201


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 5/95 (5%)

Query: 133  PTTPFSPPPP---ADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEA 189
            PT P + PP       T  P    + PA  P SP G   P   SP      P        
Sbjct: 940  PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG--PATPSPKGAPTPPAATPPSPK 997

Query: 190  GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
            G  A PSP+  P+P    P SP       P P GA
Sbjct: 998  GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA 1032



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 32/95 (33%), Positives = 36/95 (37%), Gaps = 6/95 (6%)

Query: 133  PTTPFSPPPPAD---VTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEA 189
            PTTP + PP       T  P    + PA  P SP G L     SP      P        
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL--ATPSPKGAPTTPAATPPSPK 1229

Query: 190  GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
            G  A PSP+  P+     P SP       PPP GA
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGP-ATPPPKGA 1263



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 14/118 (11%)

Query: 111  PPGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPG 170
            PP P E    ++     S  + P TP     P      P    S+P  +PA+P+ R +P 
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATP----APMGAPTLPAVIPSSPKEVPATPSSRRDP- 1526

Query: 171  LSSPFSDLLG---PLGAQADEA---GCSAQPSPERQPSPLEPR--PVSPSAYMLRLPP 220
              +P + LL    P      EA        PSP++ P+   P+  P +PS+     PP
Sbjct: 1527 -IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 32/95 (33%), Positives = 36/95 (37%), Gaps = 6/95 (6%)

Query: 133  PTTPFSPPPPAD---VTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEA 189
            PTTP + PP       T  P    + PA  P SP G L     SP      P        
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL--ATPSPKGAPTTPAATPPSPK 1206

Query: 190  GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
            G  A PSP+  P+     P SP    L  P P GA
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKG-GLATPSPKGA 1240



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 30/83 (36%), Positives = 36/83 (43%), Gaps = 9/83 (10%)

Query: 135 TPFSPP----PPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEA- 189
           TP SP     PP +     V     P   PA+PA +  P LS   S    P  A+A  A 
Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSS---SPKKARATPAP 927

Query: 190 -GCSAQPSPERQPSPLEPRPVSP 211
            G  A PSP+  P+P    P SP
Sbjct: 928 KGIPASPSPKGAPTPPAATPPSP 950



 Score = 35.8 bits (81), Expect = 0.049
 Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 6/95 (6%)

Query: 133  PTTPFSPPPPAD---VTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEA 189
            PTTP + PP       T  P    + PA  P SP G L     SP      P        
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL--ATPSPKGAPTTPAATPPSPK 1252

Query: 190  GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
            G  A P P+  P+P    P S     L  PP  GA
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKG-GLATPPHKGA 1286



 Score = 35.0 bits (79), Expect = 0.084
 Identities = 33/110 (30%), Positives = 43/110 (39%), Gaps = 19/110 (17%)

Query: 132  GPTTPF---SPPPPA----------DVTCFPVEEASAPATLPASPAGR-----LEPGL-S 172
            GP TP    +P PPA            T FP   ++ PA  P SP G      L  G  +
Sbjct: 999  GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058

Query: 173  SPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPA 222
            +P + L  P G  A  +   A   P   P   +  P +PS     +PP A
Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108



 Score = 35.0 bits (79), Expect = 0.084
 Identities = 35/112 (31%), Positives = 42/112 (37%), Gaps = 23/112 (20%)

Query: 135  TPFSPPPPADVTCFPVEEASAPATLPASPAGR-----LEPGL-SSPFSDLLGPLGAQADE 188
            TP SP      T FP   ++ PA  P SP G      L  G  ++P + L  P G  A  
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP 1074

Query: 189  A----------------GCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
            +                G  A PSP+  P P    P SP    L  PP  GA
Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG-GLATPPHKGA 1125



 Score = 35.0 bits (79), Expect = 0.084
 Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 10/97 (10%)

Query: 133  PTTPFSPPPP---ADVTCFPVEEASAPATLPASPAGRLE--PGLSSPFSDLLGPLGAQAD 187
            PT P + PP       T  P      PA  P SP G L   P   +P +    P      
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT----PAATPPS 1135

Query: 188  EAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
              G  A P P+  P+     P SP    L  PPP GA
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKG-GLATPPPKGA 1171



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 30/94 (31%), Positives = 37/94 (39%), Gaps = 8/94 (8%)

Query: 132 GPTTPFSPPPPA-DVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAG 190
           GP TP     PA  +T      +S+P    A+PA +  P   SP      P        G
Sbjct: 899 GPATPAPKQAPALSMT------SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952

Query: 191 CSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
             A PSP+  P+P    P SP       P P GA
Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGP-ATPSPKGA 985



 Score = 33.1 bits (74), Expect = 0.32
 Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 5/94 (5%)

Query: 133  PTTPFSPPPPADVTCFPVEEASA--PATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAG 190
            P    + P P  +   P  + +   PA  P SP G   P   SP      P        G
Sbjct: 918  PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG--PATPSPKWAPTPPAATPPSPKG 975

Query: 191  CSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGA 224
              A PSP+  P+P    P SP       P P GA
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGP-ATPSPKGA 1008



 Score = 33.1 bits (74), Expect = 0.32
 Identities = 27/91 (29%), Positives = 31/91 (34%), Gaps = 5/91 (5%)

Query: 133  PTTPFSPPPPAD---VTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEA 189
            PTTP + PP       T  P    + PA  P SP G   P    P      P        
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG--PATPPPKGAPTPPAATPPSLK 1275

Query: 190  GCSAQPSPERQPSPLEPRPVSPSAYMLRLPP 220
            G  A P  +  P+P    P SP       PP
Sbjct: 1276 GGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306



 Score = 32.3 bits (72), Expect = 0.55
 Identities = 35/122 (28%), Positives = 42/122 (34%), Gaps = 6/122 (4%)

Query: 106  KGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFSP-PPPADVTCFPVEEASA--PATLPAS 162
            KG S PP     S              PTTP +  P P      P  + +   PA  P S
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089

Query: 163  PAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPA 222
            P G   P   SP    + P        G  A P  +  P+     P SP   +   PPP 
Sbjct: 1090 PKGG--PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL-ATPPPK 1146

Query: 223  GA 224
            GA
Sbjct: 1147 GA 1148



 Score = 32.0 bits (71), Expect = 0.71
 Identities = 34/118 (28%), Positives = 45/118 (38%), Gaps = 13/118 (11%)

Query: 102  TTKTKGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPA 161
            T+  KG   PP     S       + S G  P    +P PPA     P    + PAT P+
Sbjct: 1303 TSPPKGAPTPPAATPPS------PKGSPGTPPPKG-APTPPAVTPPSPKGTPTLPATTPS 1355

Query: 162  SPAGRLEPGLSSPFSDLLGPLGAQADEAG-CSAQPSPERQPSPLEPR--PVSPSAYML 216
            S  G   P   S       P    + + G     PSP+R P+   P+  P SP+   L
Sbjct: 1356 SKGG---PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 25/82 (30%), Positives = 31/82 (37%), Gaps = 5/82 (6%)

Query: 133  PTTPFSPPPP--ADVTCFPVEEASAPATL-PASPAGRLEPGLSSPFSDLLGPLGAQADEA 189
            PT P + PP     +   P + A  PA + P SP G   P  S P      P        
Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG--PATSPPKGAPTPPAATPPSPK 1321

Query: 190  GCSAQPSPERQPSPLEPRPVSP 211
            G    P P+  P+P    P SP
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSP 1343



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 14/110 (12%)

Query: 128  SEGRGPTTPFSPPPPADVTCFPVEEASAPATL-----PASPA-GRLEPGLSSPFSDLLGP 181
            S  RGP  P     P      P+    APAT       A+P+ G L P   +P S    P
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447

Query: 182  LGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHS 231
              A +   G  A PS +  P+     P SP        PPA   +    S
Sbjct: 1448 --ATSAPKGGPATPSSKGDPTLPAVTPPSPK------EPPAPKQVATSSS 1489


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 43/195 (22%), Positives = 79/195 (40%), Gaps = 21/195 (10%)

Query: 98  KLRRTTKTKGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPA 157
           ++RR  + K      GP + S+ +R      E   P +P +P P    T  P ++   PA
Sbjct: 507 RVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASP-APSPAPSPTPAPPQKEQPPA 565

Query: 158 TLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLR 217
             P   A    P   +P      P+    D    +   + +R+            A   R
Sbjct: 566 ETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRR-----------QAREQR 614

Query: 218 LPPPAGAYIQNEHSYQVGSALLWKRRAEAALDALDKAQRQLQACKRREQ--RLRLRLTKL 275
                   +Q E   ++       R  + A +A  +A+R+ +A +R EQ  R + +  + 
Sbjct: 615 EREEQERRLQAERDKRM-------REEQLAREAEARAEREAEARRREEQEAREKAQAEQE 667

Query: 276 QQERAREKRAQADAR 290
           +QER ++++ +A+AR
Sbjct: 668 EQERLQKQKEEAEAR 682



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 43/177 (24%), Positives = 61/177 (34%), Gaps = 18/177 (10%)

Query: 128 SEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQAD 187
           S G G T P  PP P   T  P            SP+     G              +  
Sbjct: 483 SPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAA---GPEDKSQSKRRASNEKES 539

Query: 188 EAGCSAQPSPERQPSPLEPRPVSP------SAYMLRLPP-------PAGAYIQNEHSYQV 234
            A  S  PSP   P+P  P+   P       A +L  PP       P+          + 
Sbjct: 540 AAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEA 599

Query: 235 GSALLWKRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQ 291
              L  KRR        ++ +R+LQA   R++R+R      + E   E+ A+A  R+
Sbjct: 600 TRLLAEKRRQAREQREREEQERRLQA--ERDKRMREEQLAREAEARAEREAEARRRE 654



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 52/198 (26%), Positives = 81/198 (40%), Gaps = 26/198 (13%)

Query: 114 PAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSS 173
           PA V+R     +   EG     P  PPPP           + PA   A+ + +L     S
Sbjct: 15  PAVVARTPPEPRPSPEG----DPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPES 70

Query: 174 PFSDLLGPLGAQADEAGCSAQ-----PSPERQPSPLEPRP------VSPSAYMLRLPPPA 222
           P S  +GP  A   E   S++     P+P     P + RP       SP+A      PP 
Sbjct: 71  P-SGQVGPRPAPPQEESPSSEAKSRGPTPPAM-GPRDARPPRRSSQPSPTAVPASDSPPT 128

Query: 223 GAYIQNEHSYQVGSALLWKRRAEAALDALDK----AQRQLQACKRREQRLRLRLTKLQQE 278
              ++          L  +RR E A     K     +++ +A   RE++L+ R  +L+++
Sbjct: 129 KQEVKKAGERH---KLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQ 185

Query: 279 R--AREKRAQADARQTLK 294
           R  A ++RA  + RQ  K
Sbjct: 186 RLKAEQRRAALEERQRQK 203


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 28/86 (32%), Positives = 35/86 (40%), Gaps = 7/86 (8%)

Query: 136 PFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQP 195
           PFSPPP   V       AS P +  A+P  +  P L++P      PL         S   
Sbjct: 439 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP------PLQVPPSPP-ASPPM 491

Query: 196 SPERQPSPLEPRPVSPSAYMLRLPPP 221
           SP   P P  P P++     L  PPP
Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPP 517



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 32/92 (34%), Positives = 40/92 (43%), Gaps = 5/92 (5%)

Query: 133 PTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCS 192
           P +P + PPP       +    AP + PASP   L P L++P       L     +A  S
Sbjct: 385 PLSPLATPPPQAPPALALPPLQAPPSPPASPP--LSP-LATPSPQAPNALAVHLLQAPFS 441

Query: 193 AQPSPERQP--SPLEPRPVSPSAYMLRLPPPA 222
             PSP  Q   SP    PVSPSA      PP+
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 473



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 34/105 (32%), Positives = 42/105 (40%), Gaps = 10/105 (9%)

Query: 112 PGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEP-- 169
           P PA   R R         R P     P PP +     V  AS  +T   SPA R  P  
Sbjct: 172 PSPAMARRSRAAGTEVGLPR-PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230

Query: 170 --GLSSPFSDLLG----PLGAQADEAGCSAQPSPERQPSPLEPRP 208
             GL  P S  L     PL + A  +G SA+ +P     P +P+P
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPA-RSGPSARGTPRAPAHPSQPKP 274



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 15/94 (15%)

Query: 133 PTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCS 192
           P +P + P P       V    AP + P SP       + +PFS    P  + +      
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP------VQAPFSPPASPPVSPSATPPSQ 469

Query: 193 AQPS---PERQ--PSPLEPRPVSPSAYMLRLPPP 221
           A PS   P  Q  PSP    P+SPSA     PPP
Sbjct: 470 APPSLAAPPLQVPPSPPASPPMSPSA----TPPP 499



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 33/112 (29%), Positives = 48/112 (42%), Gaps = 22/112 (19%)

Query: 100 RRTTKTKGHSYPPGPAEVSRLRRC-----RKRCSEGRGP--TTPFSPPPPADVTCFPVEE 152
           R T +   H   P P  +  LR       RK  +   GP  ++P + P P+        +
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAAL-----Q 314

Query: 153 ASAPATLPASP-AGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSP 203
           + AP TLPA+P +  L   L++P      PL   +     SA PS +  PSP
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPL-----PLAPPSP----SAPPSLQTLPSP 357


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 28/86 (32%), Positives = 35/86 (40%), Gaps = 7/86 (8%)

Query: 136 PFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQP 195
           PFSPPP   V       AS P +  A+P  +  P L++P      PL         S   
Sbjct: 400 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP------PLQVPPSPP-ASPPM 452

Query: 196 SPERQPSPLEPRPVSPSAYMLRLPPP 221
           SP   P P  P P++     L  PPP
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPP 478



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 32/92 (34%), Positives = 40/92 (43%), Gaps = 5/92 (5%)

Query: 133 PTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCS 192
           P +P + PPP       +    AP + PASP   L P L++P       L     +A  S
Sbjct: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASPP--LSP-LATPSPQAPNALAVHLLQAPFS 402

Query: 193 AQPSPERQP--SPLEPRPVSPSAYMLRLPPPA 222
             PSP  Q   SP    PVSPSA      PP+
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 434



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 34/105 (32%), Positives = 42/105 (40%), Gaps = 10/105 (9%)

Query: 112 PGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEP-- 169
           P PA   R R         R P     P PP +     V  AS  +T   SPA R  P  
Sbjct: 163 PSPAMARRSRAAGTEVGLPR-PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 221

Query: 170 --GLSSPFSDLLG----PLGAQADEAGCSAQPSPERQPSPLEPRP 208
             GL  P S  L     PL + A  +G SA+ +P     P +P+P
Sbjct: 222 GGGLQRPASRSLSSSATPLSSPA-RSGPSARGTPRAPAHPSQPKP 265



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 24/130 (18%)

Query: 100 RRTTKTKGHSYPPGPAEVSRLRRC-----RKRCSEGRGP--TTPFSPPPPADVTCFPVEE 152
           R T +   H   P P  +  LR       RK  +   GP  ++P + P P+     P   
Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA----PPSP 306

Query: 153 ASAPA--TLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVS 210
           ++ P+  TLP+ PA        +P S     LG+   +A  S  PSP   P    P P +
Sbjct: 307 SAPPSLQTLPSPPA--------TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP-PQA 357

Query: 211 PSAYMLRLPP 220
           P A  L LPP
Sbjct: 358 PPA--LALPP 365



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 15/94 (15%)

Query: 133 PTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCS 192
           P +P + P P       V    AP + P SP       + +PFS    P  + +      
Sbjct: 377 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP------VQAPFSPPASPPVSPSATPPSQ 430

Query: 193 AQPS---PERQ--PSPLEPRPVSPSAYMLRLPPP 221
           A PS   P  Q  PSP    P+SPSA     PPP
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSA----TPPP 460


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 31/102 (30%), Positives = 35/102 (34%), Gaps = 18/102 (17%)

Query: 132 GPTTPFSPPPPADVTCFPV-------EEASAPATLPASPAGR-----LEPGLSSPFSDLL 179
           GP  P  PPPP  V   P+       +    P   P  P G+     L PG   P     
Sbjct: 245 GPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYG 304

Query: 180 GPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPP 221
            P G    + G      P   P P  PRP  P    L L PP
Sbjct: 305 PPPGPPPPQQG------PPPPPGPFPPRPPGPLGPPLTLAPP 340



 Score = 31.6 bits (70), Expect = 0.93
 Identities = 32/100 (32%), Positives = 33/100 (33%), Gaps = 21/100 (21%)

Query: 132 GPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGC 191
           GP  P  PPPP     FP      P   P  P G   P    P   +L P  A     G 
Sbjct: 219 GPAGPGGPPPP-----FPA--GQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGD 271

Query: 192 SAQP------SPERQPSPLEPRPVSPSAYMLRLPPPAGAY 225
              P       P  QP PL P P  P       PPP   Y
Sbjct: 272 RPPPPVLFPGQPFGQP-PLGPLPPGP-------PPPVPGY 303


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 23/62 (37%), Positives = 38/62 (61%), Gaps = 4/62 (6%)

Query: 238 LLWKRRAEAALDA----LDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTL 293
           LL K++AE   +A    L KA+R+ +A KRR+Q +  R   L++ER + K+ Q   R+ L
Sbjct: 147 LLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKML 206

Query: 294 KE 295
           ++
Sbjct: 207 ED 208


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 32/92 (34%), Positives = 40/92 (43%), Gaps = 5/92 (5%)

Query: 133 PTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCS 192
           P +P + PPP       +    AP + PASP   L P L++P       L     +A  S
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPP--LSP-LATPSPQAPNALAVHLLQAPFS 666

Query: 193 AQPSPERQP--SPLEPRPVSPSAYMLRLPPPA 222
             PSP  Q   SP    PVSPSA      PP+
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 7/87 (8%)

Query: 136 PFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQP 195
           PFSPPP   V       AS P +  A+P  +  P L++P      PL         S   
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP------PLQVPPSPPA-SPPM 716

Query: 196 SPERQPSPLEPRPVSPSAYMLRLPPPA 222
           SP   P P  P P++     +   PPA
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPA 743



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 34/105 (32%), Positives = 42/105 (40%), Gaps = 10/105 (9%)

Query: 112 PGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEP-- 169
           P PA   R R         R P     P PP +     V  AS  +T   SPA R  P  
Sbjct: 172 PSPAMARRSRAAGTEVGLPR-PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230

Query: 170 --GLSSPFSDLLG----PLGAQADEAGCSAQPSPERQPSPLEPRP 208
             GL  P S  L     PL + A  +G SA+ +P     P +P+P
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPA-RSGPSARGTPRAPAHPSQPKP 274



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 23/108 (21%)

Query: 131 RGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEA- 189
           + P +P + PPP   +        AP  L + P      GL SP    L PL     +A 
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPL----QGLPSP---PLSPLATPPPQAP 622

Query: 190 ------GCSAQPSPERQP--SPL-EPRPVSPSAYMLRL------PPPA 222
                    A PSP   P  SPL  P P +P+A  + L      PPP+
Sbjct: 623 PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 15/94 (15%)

Query: 133 PTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCS 192
           P +P + P P       V    AP + P SP       + +PFS    P  + +      
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPP------VQAPFSPPASPPVSPSATPPSQ 694

Query: 193 AQPS---PERQ--PSPLEPRPVSPSAYMLRLPPP 221
           A PS   P  Q  PSP    P+SPSA     PPP
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSA----TPPP 724



 Score = 31.6 bits (70), Expect = 0.93
 Identities = 37/138 (26%), Positives = 48/138 (34%), Gaps = 33/138 (23%)

Query: 100 RRTTKTKGHSYPPGPAEVSRLRRC-----RKRCSEGRGPT------------TPFSPPPP 142
           R T +   H   P P  +  LR       RK  +   GP             T   P PP
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319

Query: 143 ADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPS 202
            D    P+     PATLP SP       L++P      PL   +  A  S Q  P    +
Sbjct: 320 PDNAATPL-----PATLPPSPP------LATPL-----PLAPPSPSAPPSLQTLPSPPAT 363

Query: 203 PLEPRPVSPSAYMLRLPP 220
           P    P S +   ++ PP
Sbjct: 364 PPSQAPPSMTTPPMQAPP 381



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 8/95 (8%)

Query: 133 PTTPFS----PPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADE 188
           P  P S    PP     +  P    + PA+L   P   L      P      PL     E
Sbjct: 500 PQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE 559

Query: 189 AGCSAQPSP-ERQPSPL-EPRPVSPSAYMLRLPPP 221
                 P P +  PSPL  P P +PS+  +  PPP
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSS--IATPPP 592



 Score = 28.5 bits (62), Expect = 7.9
 Identities = 32/116 (27%), Positives = 41/116 (35%), Gaps = 29/116 (25%)

Query: 136 PFSPP--PPADVTCFPVEEA-------------SAPATLPASPAGRLEPGLSSPFSD--- 177
           PFSPP  PP   +  P  +A             S PA+ P SP+    P    P +    
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735

Query: 178 LLGPLGAQADEAGCSAQPSP-----------ERQPSPLEPRPVSPSAYMLRLPPPA 222
            + P    +     SA P P           +  PSP    P+SP A      PPA
Sbjct: 736 QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA 791


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,383,522
Number of Sequences: 37866
Number of extensions: 966250
Number of successful extensions: 8970
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 590
Number of HSP's that attempted gapping in prelim test: 7234
Number of HSP's gapped (non-prelim): 2079
length of query: 309
length of database: 18,247,518
effective HSP length: 102
effective length of query: 207
effective length of database: 14,385,186
effective search space: 2977733502
effective search space used: 2977733502
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.