BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|56676324 LEM domain containing 1 [Homo sapiens] (108 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|56676324 LEM domain containing 1 [Homo sapiens] 223 3e-59 gi|4507555 thymopoietin isoform alpha [Homo sapiens] 49 9e-07 gi|73760401 thymopoietin isoform gamma [Homo sapiens] 44 3e-05 gi|73760405 thymopoietin isoform beta [Homo sapiens] 44 3e-05 gi|31044432 LEM domain containing 2 isoform 1 [Homo sapiens] 40 3e-04 gi|7706607 LEM domain containing 3 [Homo sapiens] 39 0.001 gi|168229256 ankyrin repeat domain 41 [Homo sapiens] 37 0.004 gi|4557553 emerin [Homo sapiens] 35 0.017 gi|148664230 ankyrin repeat and LEM domain containing 2 [Homo sa... 33 0.038 gi|48255929 periphilin 1 isoform 1 [Homo sapiens] 33 0.065 gi|239755899 PREDICTED: hypothetical protein [Homo sapiens] 32 0.14 gi|239750388 PREDICTED: hypothetical protein XP_002347412 [Homo ... 32 0.14 gi|209413756 synapsin III isoform IIIg [Homo sapiens] 30 0.55 gi|209413752 synapsin III isoform IIIa [Homo sapiens] 30 0.55 gi|119220596 helios isoform 1 [Homo sapiens] 30 0.55 gi|119220592 helios isoform 2 [Homo sapiens] 30 0.55 gi|50345881 cytoplasmic polyadenylation element binding protein ... 29 0.71 gi|239757083 PREDICTED: similar to hCG1996962 [Homo sapiens] 29 0.71 gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 29 0.71 gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens] 29 0.71 gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens] 29 0.71 gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens] 29 0.71 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 29 0.93 gi|239751590 PREDICTED: hypothetical protein XP_002347921 [Homo ... 28 1.6 gi|239746102 PREDICTED: hypothetical protein XP_002343657 [Homo ... 28 1.6 gi|22748641 CHMP family, member 7 [Homo sapiens] 28 1.6 gi|223633935 hypothetical protein LOC254427 [Homo sapiens] 28 2.1 gi|4758216 dishevelled 2 [Homo sapiens] 28 2.1 gi|21389567 chemokine-like factor superfamily 2 [Homo sapiens] 28 2.1 gi|33286436 gametogenetin [Homo sapiens] 28 2.1 >gi|56676324 LEM domain containing 1 [Homo sapiens] Length = 108 Score = 223 bits (567), Expect = 3e-59 Identities = 108/108 (100%), Positives = 108/108 (100%) Query: 1 MVDVKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDG 60 MVDVKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDG Sbjct: 1 MVDVKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDG 60 Query: 61 AQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRLSRAGEKKVSQWA 108 AQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRLSRAGEKKVSQWA Sbjct: 61 AQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRLSRAGEKKVSQWA 108 >gi|4507555 thymopoietin isoform alpha [Homo sapiens] Length = 694 Score = 48.9 bits (115), Expect = 9e-07 Identities = 35/101 (34%), Positives = 52/101 (51%), Gaps = 16/101 (15%) Query: 2 VDVKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQL--------------LVSPPC 47 +DV L++ L +QL K G +PGPI+ +TRKLYEKKL++L +S Sbjct: 110 LDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSA 169 Query: 48 APPVMNGPRELDGAQDSDDSEGGLQEHQAPESHMGLSPKRE 88 NG + D + SD+ EG +EH+ +S + P E Sbjct: 170 ENTRQNGSNDSD--RYSDNEEGKKKEHKKVKSTRDIVPFSE 208 >gi|73760401 thymopoietin isoform gamma [Homo sapiens] Length = 345 Score = 43.9 bits (102), Expect = 3e-05 Identities = 22/40 (55%), Positives = 31/40 (77%) Query: 2 VDVKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQL 41 +DV L++ L +QL K G +PGPI+ +TRKLYEKKL++L Sbjct: 110 LDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKL 149 >gi|73760405 thymopoietin isoform beta [Homo sapiens] Length = 454 Score = 43.9 bits (102), Expect = 3e-05 Identities = 22/40 (55%), Positives = 31/40 (77%) Query: 2 VDVKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQL 41 +DV L++ L +QL K G +PGPI+ +TRKLYEKKL++L Sbjct: 110 LDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKL 149 >gi|31044432 LEM domain containing 2 isoform 1 [Homo sapiens] Length = 503 Score = 40.4 bits (93), Expect = 3e-04 Identities = 18/35 (51%), Positives = 25/35 (71%) Query: 7 LSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQL 41 LSD +L+ +L+ LGF PGPI +TR +Y KL +L Sbjct: 4 LSDLELRRELQALGFQPGPITDTTRDVYRNKLRRL 38 >gi|7706607 LEM domain containing 3 [Homo sapiens] Length = 911 Score = 38.9 bits (89), Expect = 0.001 Identities = 19/35 (54%), Positives = 25/35 (71%) Query: 7 LSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQL 41 LSD +L +QL + G SPGP+ STR +Y KKL +L Sbjct: 12 LSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKL 46 >gi|168229256 ankyrin repeat domain 41 [Homo sapiens] Length = 615 Score = 36.6 bits (83), Expect = 0.004 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 6/92 (6%) Query: 4 VKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQD 63 V +SD +L L LG +P PI P TR+LY ++L + ++P P EL A Sbjct: 358 VSTVSDLELLKGLRALGENPHPITPFTRQLYHQQLEEAQIAP--GPEFSGHSLELAAALR 415 Query: 64 SDDSEGGLQEHQAPESHMGLSPKRETTARKTR 95 + G + + QA E + ++ AR+ R Sbjct: 416 T----GCIPDVQADEDALAQQFEQPDPARRWR 443 >gi|4557553 emerin [Homo sapiens] Length = 254 Score = 34.7 bits (78), Expect = 0.017 Identities = 20/77 (25%), Positives = 32/77 (41%) Query: 7 LSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDD 66 LSD +L L + GP++ STR+LYEKK+ + P + D + Sbjct: 7 LSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRLSPPSSSAASSYSFSDLNS 66 Query: 67 SEGGLQEHQAPESHMGL 83 + G + P+ L Sbjct: 67 TRGDADMYDLPKKEDAL 83 >gi|148664230 ankyrin repeat and LEM domain containing 2 [Homo sapiens] Length = 938 Score = 33.5 bits (75), Expect = 0.038 Identities = 16/40 (40%), Positives = 25/40 (62%) Query: 4 VKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQLLV 43 +K L+ L+ ++ K G GPI +TR ++EKKL Q L+ Sbjct: 72 LKLLNPDDLREEIVKAGLKCGPITSTTRFIFEKKLAQALL 111 >gi|48255929 periphilin 1 isoform 1 [Homo sapiens] Length = 458 Score = 32.7 bits (73), Expect = 0.065 Identities = 15/50 (30%), Positives = 25/50 (50%) Query: 49 PPVMNGPRELDGAQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRLSR 98 PPV N + DG +++ E Q P++ L P+++ R T+L R Sbjct: 352 PPVRNTEMDHDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRR 401 >gi|239755899 PREDICTED: hypothetical protein [Homo sapiens] Length = 459 Score = 31.6 bits (70), Expect = 0.14 Identities = 17/58 (29%), Positives = 27/58 (46%) Query: 46 PCAPPVMNGPRELDGAQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRLSRAGEKK 103 P AP + R + DD G + + P+S SP+R + K + R+GE+K Sbjct: 257 PLAPIAVPAQRLQQSQRTGDDPARGWEWQRGPQSQKEASPRRGEYSGKGQRERSGERK 314 >gi|239750388 PREDICTED: hypothetical protein XP_002347412 [Homo sapiens] Length = 459 Score = 31.6 bits (70), Expect = 0.14 Identities = 17/58 (29%), Positives = 27/58 (46%) Query: 46 PCAPPVMNGPRELDGAQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRLSRAGEKK 103 P AP + R + DD G + + P+S SP+R + K + R+GE+K Sbjct: 257 PLAPIAVPAQRLQQSQRTGDDPARGWEWQRGPQSQKEASPRRGEYSGKGQRERSGERK 314 >gi|209413756 synapsin III isoform IIIg [Homo sapiens] Length = 579 Score = 29.6 bits (65), Expect = 0.55 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 10/90 (11%) Query: 20 GFSPGPILP------STRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDDSEGGLQ- 72 G +P P+ P S + + +L L P PP GPR+ Q Q Sbjct: 400 GTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQR 459 Query: 73 ---EHQAPESHMGLSPKRETTARKTRLSRA 99 + Q P S SP+++ + +LSRA Sbjct: 460 LSPQGQQPLSPQSGSPQQQRSPGSPQLSRA 489 >gi|209413752 synapsin III isoform IIIa [Homo sapiens] Length = 580 Score = 29.6 bits (65), Expect = 0.55 Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 10/90 (11%) Query: 20 GFSPGPILP------STRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDDSEGGLQ- 72 G +P P+ P S + + +L L P PP GPR+ Q Q Sbjct: 401 GTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSPSQQR 460 Query: 73 ---EHQAPESHMGLSPKRETTARKTRLSRA 99 + Q P S SP+++ + +LSRA Sbjct: 461 LSPQGQQPLSPQSGSPQQQRSPGSPQLSRA 490 >gi|119220596 helios isoform 1 [Homo sapiens] Length = 526 Score = 29.6 bits (65), Expect = 0.55 Identities = 12/26 (46%), Positives = 17/26 (65%) Query: 63 DSDDSEGGLQEHQAPESHMGLSPKRE 88 DS DSE +HQ+ + H L+PKR+ Sbjct: 406 DSTDSESSHDDHQSYQGHPALNPKRK 431 >gi|119220592 helios isoform 2 [Homo sapiens] Length = 500 Score = 29.6 bits (65), Expect = 0.55 Identities = 12/26 (46%), Positives = 17/26 (65%) Query: 63 DSDDSEGGLQEHQAPESHMGLSPKRE 88 DS DSE +HQ+ + H L+PKR+ Sbjct: 380 DSTDSESSHDDHQSYQGHPALNPKRK 405 >gi|50345881 cytoplasmic polyadenylation element binding protein 3 [Homo sapiens] Length = 698 Score = 29.3 bits (64), Expect = 0.71 Identities = 26/73 (35%), Positives = 29/73 (39%), Gaps = 7/73 (9%) Query: 25 PILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDDSEGGLQEHQAPESHMGLS 84 P+ T K E V L SP APP NGP D Q GL HQ P+ Sbjct: 39 PLSSETPKPEENSAVPAL-SPAAAPPAPNGP---DKMQMESPLLPGLSFHQPPQQP---P 91 Query: 85 PKRETTARKTRLS 97 P +E A LS Sbjct: 92 PPQEPAAPGASLS 104 >gi|239757083 PREDICTED: similar to hCG1996962 [Homo sapiens] Length = 192 Score = 29.3 bits (64), Expect = 0.71 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 11/95 (11%) Query: 24 GPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDS------DDSEGGLQEHQAP 77 GP +P + ++ V +LV+PP PP L A S D G P Sbjct: 84 GPGMPCAPRAQRREAVGVLVAPPRVPPRTPRRGSLGAAVFSSSDLTFDAEAQGQVRRPRP 143 Query: 78 ESHMGLSPKRETTA-----RKTRLSRAGEKKVSQW 107 +G S R A + R RAG SQW Sbjct: 144 AQAVGPSGARRPEAPGWFRKSDRSGRAGTGAWSQW 178 >gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] Length = 2240 Score = 29.3 bits (64), Expect = 0.71 Identities = 15/43 (34%), Positives = 23/43 (53%) Query: 54 GPRELDGAQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRL 96 GP E G++ SD EG L Q PE+ G+ + R+++L Sbjct: 196 GPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKL 238 >gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens] Length = 1189 Score = 29.3 bits (64), Expect = 0.71 Identities = 15/43 (34%), Positives = 23/43 (53%) Query: 54 GPRELDGAQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRL 96 GP E G++ SD EG L Q PE+ G+ + R+++L Sbjct: 196 GPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKL 238 >gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens] Length = 562 Score = 29.3 bits (64), Expect = 0.71 Identities = 15/43 (34%), Positives = 23/43 (53%) Query: 54 GPRELDGAQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRL 96 GP E G++ SD EG L Q PE+ G+ + R+++L Sbjct: 196 GPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKL 238 >gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens] Length = 562 Score = 29.3 bits (64), Expect = 0.71 Identities = 15/43 (34%), Positives = 23/43 (53%) Query: 54 GPRELDGAQDSDDSEGGLQEHQAPESHMGLSPKRETTARKTRL 96 GP E G++ SD EG L Q PE+ G+ + R+++L Sbjct: 196 GPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKL 238 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 28.9 bits (63), Expect = 0.93 Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 22 SPGPILPSTRKLYE--KKLVQLLVSP-PCAPPVMNGPRELDGAQDSDDSEGGLQEHQAPE 78 SPGP P K E + L SP P PP + GP LDG D D + GL+ P Sbjct: 1175 SPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGL-DGKDGKPGLRGDPGPA 1233 Query: 79 SHMGL 83 GL Sbjct: 1234 GPPGL 1238 >gi|239751590 PREDICTED: hypothetical protein XP_002347921 [Homo sapiens] Length = 192 Score = 28.1 bits (61), Expect = 1.6 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 11/95 (11%) Query: 24 GPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDS------DDSEGGLQEHQAP 77 GP +P + ++ V +LV+PP PP L A S D G P Sbjct: 84 GPGMPCAPRAQRREAVGVLVAPPRVPPRTPRRGSLGVAVFSSSDLTFDAEAQGQVRRPRP 143 Query: 78 ESHMGLSPKRETTA-----RKTRLSRAGEKKVSQW 107 +G S R A + R RAG SQW Sbjct: 144 AQAVGPSGARRPEAPGWFRKSDRSGRAGTGAWSQW 178 >gi|239746102 PREDICTED: hypothetical protein XP_002343657 [Homo sapiens] Length = 192 Score = 28.1 bits (61), Expect = 1.6 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 11/95 (11%) Query: 24 GPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDS------DDSEGGLQEHQAP 77 GP +P + ++ V +LV+PP PP L A S D G P Sbjct: 84 GPGMPCAPRAQRREAVGVLVAPPRVPPRTPRRGSLGVAVFSSSDLTFDAEAQGQVRRPRP 143 Query: 78 ESHMGLSPKRETTA-----RKTRLSRAGEKKVSQW 107 +G S R A + R RAG SQW Sbjct: 144 AQAVGPSGARRPEAPGWFRKSDRSGRAGTGAWSQW 178 >gi|22748641 CHMP family, member 7 [Homo sapiens] Length = 453 Score = 28.1 bits (61), Expect = 1.6 Identities = 11/25 (44%), Positives = 19/25 (76%) Query: 7 LSDCKLQNQLEKLGFSPGPILPSTR 31 +SD +L+ +LEKL S G ++PS++ Sbjct: 416 ISDAELEAELEKLSLSEGGLVPSSK 440 >gi|223633935 hypothetical protein LOC254427 [Homo sapiens] Length = 435 Score = 27.7 bits (60), Expect = 2.1 Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 16/47 (34%) Query: 17 EKLGFSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQD 63 + L F PGP LPSTR A GPR+ +GAQD Sbjct: 364 KSLCFRPGPALPSTR----------------ARQSFPGPRQPNGAQD 394 >gi|4758216 dishevelled 2 [Homo sapiens] Length = 736 Score = 27.7 bits (60), Expect = 2.1 Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 60 GAQDSDDSEG--GLQEHQAPESHMGLSPKRETTARKTRLSRAGE 101 G+ SD G G E +APES G + E ++R L R GE Sbjct: 593 GSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGE 636 >gi|21389567 chemokine-like factor superfamily 2 [Homo sapiens] Length = 248 Score = 27.7 bits (60), Expect = 2.1 Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 4/52 (7%) Query: 46 PCAPPVMNGPRE--LDGAQDSDDSEGGLQEHQAP--ESHMGLSPKRETTARK 93 P PP P E DG + SD + +Q+H+ P + + PK E R+ Sbjct: 15 PAPPPPGAKPEEDKKDGKEPSDKPQKAVQDHKEPSDKPQKAVQPKHEVGTRR 66 >gi|33286436 gametogenetin [Homo sapiens] Length = 652 Score = 27.7 bits (60), Expect = 2.1 Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 8/71 (11%) Query: 21 FSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDDSEGGLQEH------ 74 + P P LPS R+ ++++ L + P +PP + + Q + + GG H Sbjct: 171 WKPPPPLPSERQPADRRITPALAT-PASPPTESQAGPRNQGQTAGRARGGAPPHAGEGEM 229 Query: 75 -QAPESHMGLS 84 Q +S GLS Sbjct: 230 AQPADSESGLS 240 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.130 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,149,149 Number of Sequences: 37866 Number of extensions: 243403 Number of successful extensions: 700 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 641 Number of HSP's gapped (non-prelim): 86 length of query: 108 length of database: 18,247,518 effective HSP length: 78 effective length of query: 30 effective length of database: 15,293,970 effective search space: 458819100 effective search space used: 458819100 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.