BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens] (937 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens] 1896 0.0 gi|21264369 nucleoporin 98kD isoform 2 [Homo sapiens] 1850 0.0 gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens] 1839 0.0 gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens] 1839 0.0 gi|33946327 nucleoporin 214kDa [Homo sapiens] 107 4e-23 gi|89276766 trophinin isoform 5 [Homo sapiens] 104 3e-22 gi|161016767 mucin 21 [Homo sapiens] 95 3e-19 gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 91 5e-18 gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 90 1e-17 gi|62122917 filaggrin family member 2 [Homo sapiens] 88 4e-17 gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 87 6e-17 gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 82 2e-15 gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 82 2e-15 gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 82 2e-15 gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 82 2e-15 gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 82 2e-15 gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 82 2e-15 gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 82 2e-15 gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 82 3e-15 gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 82 3e-15 gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 82 3e-15 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 79 2e-14 gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 79 2e-14 gi|24430146 nucleoporin 153kDa [Homo sapiens] 78 3e-14 gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] 75 3e-13 gi|89026265 PREDICTED: mucin 12 [Homo sapiens] 74 8e-13 gi|24497609 nucleoporin 62kDa [Homo sapiens] 73 1e-12 gi|24497607 nucleoporin 62kDa [Homo sapiens] 73 1e-12 gi|24497605 nucleoporin 62kDa [Homo sapiens] 73 1e-12 gi|24497603 nucleoporin 62kDa [Homo sapiens] 73 1e-12 >gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens] Length = 937 Score = 1896 bits (4912), Expect = 0.0 Identities = 937/937 (100%), Positives = 937/937 (100%) Query: 1 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG Sbjct: 1 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60 Query: 61 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF Sbjct: 61 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120 Query: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST Sbjct: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180 Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL Sbjct: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240 Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF Sbjct: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300 Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV Sbjct: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360 Query: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIF 420 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIF Sbjct: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIF 420 Query: 421 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG Sbjct: 421 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480 Query: 481 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 540 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA Sbjct: 481 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 540 Query: 541 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 600 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL Sbjct: 541 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 600 Query: 601 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 660 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT Sbjct: 601 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 660 Query: 661 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 720 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE Sbjct: 661 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 720 Query: 721 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 780 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD Sbjct: 721 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 780 Query: 781 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 840 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP Sbjct: 781 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 840 Query: 841 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 900 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS Sbjct: 841 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 900 Query: 901 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQVEKKGQ 937 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQVEKKGQ Sbjct: 901 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQVEKKGQ 937 >gi|21264369 nucleoporin 98kD isoform 2 [Homo sapiens] Length = 920 Score = 1850 bits (4793), Expect = 0.0 Identities = 920/937 (98%), Positives = 920/937 (98%), Gaps = 17/937 (1%) Query: 1 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG Sbjct: 1 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60 Query: 61 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF Sbjct: 61 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120 Query: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST Sbjct: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180 Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL Sbjct: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240 Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF Sbjct: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300 Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV Sbjct: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360 Query: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIF 420 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG FGTNTSGNSIF Sbjct: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG-----------------FGTNTSGNSIF 403 Query: 421 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG Sbjct: 404 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 463 Query: 481 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 540 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA Sbjct: 464 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 523 Query: 541 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 600 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL Sbjct: 524 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 583 Query: 601 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 660 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT Sbjct: 584 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 643 Query: 661 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 720 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE Sbjct: 644 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 703 Query: 721 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 780 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD Sbjct: 704 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 763 Query: 781 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 840 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP Sbjct: 764 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 823 Query: 841 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 900 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS Sbjct: 824 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 883 Query: 901 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQVEKKGQ 937 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQVEKKGQ Sbjct: 884 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQVEKKGQ 920 >gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens] Length = 1726 Score = 1839 bits (4763), Expect = 0.0 Identities = 914/931 (98%), Positives = 914/931 (98%), Gaps = 17/931 (1%) Query: 1 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG Sbjct: 1 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60 Query: 61 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF Sbjct: 61 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120 Query: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST Sbjct: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180 Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL Sbjct: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240 Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF Sbjct: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300 Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV Sbjct: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360 Query: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIF 420 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG FGTNTSGNSIF Sbjct: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG-----------------FGTNTSGNSIF 403 Query: 421 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG Sbjct: 404 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 463 Query: 481 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 540 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA Sbjct: 464 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 523 Query: 541 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 600 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL Sbjct: 524 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 583 Query: 601 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 660 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT Sbjct: 584 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 643 Query: 661 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 720 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE Sbjct: 644 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 703 Query: 721 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 780 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD Sbjct: 704 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 763 Query: 781 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 840 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP Sbjct: 764 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 823 Query: 841 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 900 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS Sbjct: 824 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 883 Query: 901 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQ 931 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQ Sbjct: 884 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQ 914 >gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens] Length = 1800 Score = 1839 bits (4763), Expect = 0.0 Identities = 914/931 (98%), Positives = 914/931 (98%), Gaps = 17/931 (1%) Query: 1 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG Sbjct: 1 MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60 Query: 61 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF Sbjct: 61 GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120 Query: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST Sbjct: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180 Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL Sbjct: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240 Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF Sbjct: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300 Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV Sbjct: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360 Query: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIF 420 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG FGTNTSGNSIF Sbjct: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG-----------------FGTNTSGNSIF 403 Query: 421 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG Sbjct: 404 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 463 Query: 481 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 540 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA Sbjct: 464 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 523 Query: 541 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 600 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL Sbjct: 524 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 583 Query: 601 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 660 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT Sbjct: 584 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 643 Query: 661 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 720 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE Sbjct: 644 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 703 Query: 721 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 780 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD Sbjct: 704 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 763 Query: 781 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 840 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP Sbjct: 764 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 823 Query: 841 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 900 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS Sbjct: 824 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 883 Query: 901 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQ 931 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQ Sbjct: 884 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQ 914 >gi|33946327 nucleoporin 214kDa [Homo sapiens] Length = 2090 Score = 107 bits (268), Expect = 4e-23 Identities = 126/463 (27%), Positives = 192/463 (41%), Gaps = 96/463 (20%) Query: 8 TPFGGGTGGFGTTSTFGQNTG---------------------FGTTSGGAFGTSAFGSSN 46 TP G S FGQ TG FGTT+ G FG + FG ++ Sbjct: 1671 TPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQAS 1730 Query: 47 NTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFG---FGTSTGTANTLFGTASTGTSLFS 103 +FG S + +F SFSQP S+ FG T T T+ ++FG AS S S Sbjct: 1731 ----VFGQSASSAASVF---SFSQPGFSSVPAFGQPASSTPTSTSGSVFGAAS---STSS 1780 Query: 104 SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS---NPFGSTSGSLFGPSSFTAAPTGT 160 S + +F Q+ P + GGLFG +N + +P GS+FG +S T Sbjct: 1781 SSSFSFGQSSPN---------TGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAAT 1831 Query: 161 T-IKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQV 219 + F +G + V ++ + + S + + G Sbjct: 1832 SGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSG------SVFGSGNTGR---- 1881 Query: 220 GAGTTTGLFGS--------SPATSSATGLFSSSTTNSGFAYGQN--KTAFGTSTTGFGTN 269 G G +GL G +P +S++ G S++T+N+ +G + KT G +++ FG Sbjct: 1882 GGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQ 1941 Query: 270 -PGGLFGQQNQQTTSLFSKPFGQATTTQNTGFS----FGNTSTIG-QPSTNTMGLFGVTQ 323 P G F S+ S+ FG ++ + GF FG+ T G P + FG Sbjct: 1942 KPTGTFSSGGG---SVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAP 1998 Query: 324 ASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGS-STTSAPS 382 A F + ++ G FG GT GFG+ +T T+FG+ ++ +AP+ Sbjct: 1999 A------FTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNT-------TSFGTLASQNAPT 2045 Query: 383 FGT----TSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFG 421 FG+ TSG FG + + G + T F FG+N S FG Sbjct: 2046 FGSLSQQTSG--FGTQSSGFSGFGSGTGGFSFGSNNSSVQGFG 2086 Score = 105 bits (263), Expect = 2e-22 Identities = 132/490 (26%), Positives = 201/490 (41%), Gaps = 96/490 (19%) Query: 93 GTASTGTSLFSSQNNAFAQNKPTGFGNFGTST----SSGGLFGTTNTTSNPFGSTSGSLF 148 GTA++ TSL + +A A TG + T SS + G T T+ S++G + Sbjct: 1552 GTAASSTSLVAL--SAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI-SSAGPVA 1608 Query: 149 GPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDY 208 +S T + TT P + V++ S Q A S + +L Sbjct: 1609 VETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASS---SSAFNQLTNNTA 1665 Query: 209 QANRKGPQ-NQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFG 267 A P QV A T LFG ++++T + ++SGF S+ FG Sbjct: 1666 TAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGF-----------SSPAFG 1714 Query: 268 TNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQP 327 T G+FGQ TT + FGQ+ ++ + FSF QP +++ FG +S P Sbjct: 1715 TTAPGVFGQ----TTFGQASVFGQSASSAASVFSFS------QPGFSSVPAFGQPASSTP 1764 Query: 328 ----GGLFGTATNTSTGTAFG-------TGTGLFGQTNT-------GFGAVGSTLFGNNK 369 G +FG A++TS+ ++F TG GLFGQ+N GFG GS G + Sbjct: 1765 TSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSA 1824 Query: 370 LTTF----GSSTTSAPSFGTTS-GGLFGNKPT---LTLGTNTNTSN---FGFGTNTSGNS 418 TT G S A FG+++ G +FG + + G +++S+ FG G G Sbjct: 1825 ATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGG 1884 Query: 419 IF---GSKPAPGTLG----TGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP--- 468 F G KP+ + GFG+ + ++LFGN+ K G + +FG Sbjct: 1885 FFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPT 1944 Query: 469 ---------------GFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPF 513 GF++ T GFGA APV + P + F Sbjct: 1945 GTFSSGGGSVASQGFGFSSPNKTGGFGA--APVFGSPPTFGGSP--------GFGGVPAF 1994 Query: 514 GDSPLFRNPM 523 G +P F +P+ Sbjct: 1995 GSAPAFTSPL 2004 Score = 100 bits (249), Expect = 6e-21 Identities = 146/506 (28%), Positives = 208/506 (41%), Gaps = 116/506 (22%) Query: 8 TPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTS---AFGSSNNTGGLFGNSQTKPGGLFG 64 TP T + FGT + G+ + A SS+ L N+ T P Sbjct: 1614 TPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSA--- 1670 Query: 65 TSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTST 124 T F Q A ST+ FG TG+ TAST A Q +GF + T Sbjct: 1671 TPVFGQVAASTAPSL-FGQQTGS------TASTAA--------ATPQVSSSGFSSPAFGT 1715 Query: 125 SSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184 ++ G+FG T FG S +FG S+ +AA + F+ P G S+ Sbjct: 1716 TAPGVFGQTT-----FGQAS--VFGQSASSAA---SVFSFSQP---------GFSS---- 1752 Query: 185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL-FSS 243 + A + P + T+ +FG++ +TSS++ F Sbjct: 1753 ----VPAFGQ--------------------PASSTPTSTSGSVFGAASSTSSSSSFSFGQ 1788 Query: 244 STTNSGFA-YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 S+ N+G +GQ+ + FG +PG FGQ S+F TT +GFSF Sbjct: 1789 SSPNTGGGLFGQS------NAPAFGQSPG--FGQGG----SVFGGTSAATTTAATSGFSF 1836 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGL-FGTATNTSTGTAFGTG-TGLFGQTNTGFGAV 360 S G S+NT +FG QA+ GG+ FG +++S+G+ FG+G TG G +G G Sbjct: 1837 CQASGFG--SSNTGSVFG--QAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFFSGLGGK 1892 Query: 361 GSTLFGNNKLTT-----FGSSTTSAPS--FGTTSGGLFG---------NKPTLTL---GT 401 S N + FGS+ TS S FG + FG KPT T G Sbjct: 1893 PSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGG 1952 Query: 402 NTNTSNFGFGT-NTSGNSIFGSKPAPGTLGT-GLGAGFGTALGAGQASLFGNNQPKIGGP 459 + + FGF + N +G FG+ P G+ T G GFG G A F + GG Sbjct: 1953 SVASQGFGFSSPNKTGG--FGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGK 2010 Query: 460 L---GTGA--FGAPGFNTTTATLGFG 480 + GT A G GF +++ T FG Sbjct: 2011 VFGEGTAAASAGGFGFGSSSNTTSFG 2036 Score = 90.1 bits (222), Expect = 9e-18 Identities = 116/382 (30%), Positives = 160/382 (41%), Gaps = 61/382 (15%) Query: 5 SFGTPFGGGTGGFGTTSTFGQNTGFG--TTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62 S + F GF + FGQ +TSG FG ++ SS+++ +S GGL Sbjct: 1738 SAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGL 1797 Query: 63 FGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT 122 FG S + PA S GFG G S +FG S T+ ++ +F Q +GFG Sbjct: 1798 FGQS--NAPAFGQSPGFGQGGS------VFGGTSAATTTAATSGFSFCQ--ASGFG---- 1843 Query: 123 STSSGGLFGTTNTTSN-PFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181 S+++G +FG +T FG S S G S F + TG F G S + Sbjct: 1844 SSNTGSVFGQAASTGGIVFGQQSSSSSG-SVFGSGNTGRGGGFFSGLG------GKPSQD 1896 Query: 182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241 + K+ +A + S + +N GA T G SS TG F Sbjct: 1897 AANKNPFSSASGGFGSTA---------TSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTF 1947 Query: 242 SS---STTNSGFAYGQ-NKT-------AFGTSTTGFGTNPG----GLFGQQNQQTTSLFS 286 SS S + GF + NKT FG+ T FG +PG FG T+ L S Sbjct: 1948 SSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPT-FGGSPGFGGVPAFGSAPAFTSPLGS 2006 Query: 287 ---KPFGQATTTQNT-GFSFG---NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTST 339 K FG+ T + GF FG NT++ G ++ FG SQ FGT ++ + Sbjct: 2007 TGGKVFGEGTAAASAGGFGFGSSSNTTSFGTLASQNAPTFG--SLSQQTSGFGTQSSGFS 2064 Query: 340 GTAFGTGTGLFGQTNT---GFG 358 G GTG FG N+ GFG Sbjct: 2065 GFGSGTGGFSFGSNNSSVQGFG 2086 Score = 59.3 bits (142), Expect = 2e-08 Identities = 51/143 (35%), Positives = 68/143 (47%), Gaps = 16/143 (11%) Query: 3 NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62 ++ FG TGGFG FG FG S G G AFGS+ + T P G Sbjct: 1956 SQGFGFSSPNKTGGFGAAPVFGSPPTFG-GSPGFGGVPAFGSA--------PAFTSPLGS 2006 Query: 63 FGTSSFSQ-PATSTSTGFGFGTSTGTANTLFGT-ASTGTSLFS--SQNNAFAQNKPTGFG 118 G F + A +++ GFGFG+S+ T T FGT AS F SQ + + +GF Sbjct: 2007 TGGKVFGEGTAAASAGGFGFGSSSNT--TSFGTLASQNAPTFGSLSQQTSGFGTQSSGFS 2064 Query: 119 NFGTSTSSGGLFGTTNTTSNPFG 141 FG+ T G FG+ N++ FG Sbjct: 2065 GFGSGT-GGFSFGSNNSSVQGFG 2086 Score = 53.1 bits (126), Expect = 1e-06 Identities = 97/425 (22%), Positives = 159/425 (37%), Gaps = 70/425 (16%) Query: 162 IKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVG- 220 +K NP T + M + + T H +T + ++K + GP G Sbjct: 1128 LKNNPATPSTAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLIN----SLKPSGPTPASGQ 1183 Query: 221 ------AGTTTGLFGSSPATSSATGLFSS----STTNSGFAYGQ-NKTAFGTSTTGFGTN 269 A T + + +T SA+G FS S + +GF +G T T G Sbjct: 1184 LSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGAT 1243 Query: 270 PGGLFGQQNQQTTSLF-SKPFGQATTTQN--TGFSFGNTSTIGQPSTNTMGLFGVTQASQ 326 P Q +S SKP +A + +G + + +T G+P+ ++ S+ Sbjct: 1244 PSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASS---------SR 1294 Query: 327 PGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTT 386 P GTA +T T + T G+ G TL + L + ++ P+ + Sbjct: 1295 PVAPSGTALST-TSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKAS 1353 Query: 387 SGGLFGNKPTLTLGTNTNTSNFGF---------------------------GTNTSGNSI 419 S L +PT T G S F F T+TS ++ Sbjct: 1354 STSLTSTQPTKTSGV---PSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAV 1410 Query: 420 FGSKPAPGTLGTGLGAGFGTALGAGQASL-FGNNQ-----PKIGGPLGTGAFGAPGFNTT 473 FGS P +G+ + GT+L AG+ S FG+ Q P P T A P T+ Sbjct: 1411 FGSLPVTSAGSSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLP---TS 1467 Query: 474 TATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERL 533 TL FG+ + + T P+ + ++ +S GDS + + S ++++ Sbjct: 1468 FPTLSFGSLLS--SATTPSLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQ 1525 Query: 534 KPTNP 538 P P Sbjct: 1526 LPQAP 1530 Score = 51.2 bits (121), Expect = 4e-06 Identities = 102/387 (26%), Positives = 139/387 (35%), Gaps = 62/387 (16%) Query: 69 SQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGG 128 + PAT ST G TA T + + + Q + KP+G SSG Sbjct: 1130 NNPATP-STAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGD 1188 Query: 129 -LFGT----TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183 GT T TS P S SG P SF+ + TG PT + A +T S Sbjct: 1189 KASGTAKIETAVTSTP--SASGQFSKPFSFSPSGTGFNFGIITPTPSSNFTAAQGATP-S 1245 Query: 184 TKHQCITAMKEYESKSLEELRLEDYQA--NRKGPQNQVGAGTTT----GLFGSSPATSSA 237 TK + ++ S Y+A P A TT S P S Sbjct: 1246 TKES-----SQPDAFSSGGGSKPSYEAIPESSPPSGITSASNTTPGEPAASSSRPVAPSG 1300 Query: 238 TGLFSSSTTNSGFAYGQNKTA---FGTSTTG--FGTNPGGLFGQQNQQTTSLFSKPFGQA 292 T L STT+S +K F +S G G+ G GQ + T KP +A Sbjct: 1301 TAL---STTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVGQADDST-----KPTNKA 1352 Query: 293 TTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ 352 ++T T S T T G PS V + +AT TS T T Sbjct: 1353 SSTSLT--STQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPAATSTS---- 1406 Query: 353 TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGT 412 + +FG+ +T+ GSS SFG TS + ++F FG+ Sbjct: 1407 --------STAVFGSLPVTSAGSS--GVISFGGTS-------------LSAGKTSFSFGS 1443 Query: 413 NTSGNSIFGSKPAPGTLGTGLGAGFGT 439 + +++ S P P T T L F T Sbjct: 1444 QQTNSTVPPSAPPPTTAATPLPTSFPT 1470 Score = 38.9 bits (89), Expect = 0.023 Identities = 69/316 (21%), Positives = 118/316 (37%), Gaps = 45/316 (14%) Query: 18 GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77 G T GQ + SG A +A S+ + G F +KP FS + T Sbjct: 1176 GPTPASGQLSSGDKASGTAKIETAVTSTPSASGQF----SKP--------FSFSPSGTGF 1223 Query: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ---NKPTGFGNFGTSTSSGGLFGTTN 134 FG T T ++N +T ++ SSQ +AF+ +KP+ + S+ G+ +N Sbjct: 1224 NFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPS-YEAIPESSPPSGITSASN 1282 Query: 135 TTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV-------------------K 175 TT ++S PS + T + ++ PP+ ++ + Sbjct: 1283 TTPGEPAASSSRPVAPSGTALSTTSSKLE-TPPSKLGELLFPSSLAGETLGSFSGLRVGQ 1341 Query: 176 AGVSTNISTKHQCITAMKEYESKSLEELRLEDYQA----NRKGPQNQVGAGTTTGLFGSS 231 A ST + K + +K+ ++ A + + TTT + + Sbjct: 1342 ADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPA 1401 Query: 232 PATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQ 291 ++S+T +F S S + G +FG ++ G QQ T + P Sbjct: 1402 ATSTSSTAVFGSLPVTSAGSSG--VISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTT 1459 Query: 292 ATTTQNTGF---SFGN 304 A T T F SFG+ Sbjct: 1460 AATPLPTSFPTLSFGS 1475 Score = 37.4 bits (85), Expect = 0.066 Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 26/116 (22%) Query: 6 FGTP-FGGGTGGFGTTSTFGQNTGF----GTTSGGAFGTSA---------FGSSNNTGGL 51 FG+P GG+ GFG FG F G+T G FG FGSS+NT Sbjct: 1976 FGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSF 2035 Query: 52 ----------FGNSQTKPGGLFGTSSFSQPATSTSTG-FGFGTSTGTANTLFGTAS 96 FG+ + G FGT S + TG F FG++ + G S Sbjct: 2036 GTLASQNAPTFGSLSQQTSG-FGTQSSGFSGFGSGTGGFSFGSNNSSVQGFGGWRS 2090 >gi|89276766 trophinin isoform 5 [Homo sapiens] Length = 1431 Score = 104 bits (260), Expect = 3e-22 Identities = 148/519 (28%), Positives = 205/519 (39%), Gaps = 117/519 (22%) Query: 5 SFGTPFGGGTGGFGTTST---FGQNTGFGTTSGGAFGTS-AFGSSNNTGGLFG---NSQT 57 SFG+ TG G ST FG GG+ GTS +FGS+ NT +G ++ T Sbjct: 978 SFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNT 1037 Query: 58 KPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS--QNNAFAQNKPT 115 GG TS + STS GFG +T N FG A + ++ FS +A P Sbjct: 1038 DFGGTLSTSVCFGGSPSTSAGFGGALNT---NASFGCAVSTSASFSGAVSTSACFSGAPI 1094 Query: 116 GFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVK 175 FG + S+ FG +T+ FG T + G F AAP+ T++ F GT Sbjct: 1095 TNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIG---FGAAPS-TSVSFGGAHGTSLCFG 1150 Query: 176 AGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVG--AGTTTGLFGSSPA 233 ST++ + S S L GP + +G T+ F P+ Sbjct: 1151 GAPSTSLC-----------FGSASNTNLCFG-------GPPSTSACFSGATSPSFCDGPS 1192 Query: 234 TSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQAT 293 TS+ + +TN+GF G N +A GFG GGL Sbjct: 1193 TSTGFSFGNGLSTNAGFGGGLNTSA------GFG---GGL-------------------- 1223 Query: 294 TTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQT 353 + GFS G +++ G G+ ++ GG G T+T G GT G G Sbjct: 1224 -GTSAGFSGGLSTSSGFDG-------GLGTSAGFGG--GPGTSTGFGGGLGTSAGFSGGL 1273 Query: 354 NTGFGAVGSTLFGNNKLTT--FGSSTTSAPSFGTT-------SGGL-----FGNKPTLTL 399 T G FG +T+ FG + SFG+T SGGL FG++P + Sbjct: 1274 GTSAG------FGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASF 1327 Query: 400 GTNTNT-SNFGFGTNTS----------------GNSIFGSKPAPGTLGTGLGAGFGTALG 442 +T FG G+NTS +SI G P T G G +G T+ Sbjct: 1328 DRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPST-GVGFCSGPSTSGF 1386 Query: 443 AGQASL---FGNNQPKIGGPLGTGAFGAPGFNTTTATLG 478 +G S FG P G G G + GF + A+LG Sbjct: 1387 SGGPSTGAGFGGG-PNTGAGFGGGPSTSAGFGSGAASLG 1424 Score = 99.4 bits (246), Expect = 1e-20 Identities = 148/522 (28%), Positives = 205/522 (39%), Gaps = 81/522 (15%) Query: 5 SFGTPFGGGTGGFGTTS-TFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLF 63 SFG T S +FG + G +S G + + G + + GG Sbjct: 794 SFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTL 853 Query: 64 GTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTS 123 T++ STST FG +T T + + STG S + F P+ G+FG + Sbjct: 854 STTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFG-GSPSSSGSFGGT 912 Query: 124 TSSGGLFGTTNTTSNPFGST--SGSLFGPSSFTAAPTGTTIKF------NPPTGTDTMVK 175 S+ FG + TS FG T + FG SS T+A G T+ +P TG Sbjct: 913 LSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGA 972 Query: 176 AGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATS 235 S + + T S S + G +T+ FG SP TS Sbjct: 973 LNTSASFGSVLNTSTGFGGAMSTSAD----------------FGGTLSTSVCFGGSPGTS 1016 Query: 236 SATGLFSSSTTNSGF--AYGQNKTAFGTSTTG--FGTNP---GGLFGQQNQ--------Q 280 + G S+ TN+G+ A N GT +T FG +P G G N Sbjct: 1017 VSFG--SALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVS 1074 Query: 281 TTSLFSKPF-------GQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGT 333 T++ FS G T G +F ++ G + +T FG T ++ G FG Sbjct: 1075 TSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFG-GALSTAADFGGTPSNSIG--FGA 1131 Query: 334 ATNTSTGTAFGTGTGL-FG---QTNTGFGAVGST--LFGNNKLTTFGSSTTSAPSF---- 383 A +TS GT L FG T+ FG+ +T FG T+ S ++PSF Sbjct: 1132 APSTSVSFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGP 1191 Query: 384 GTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTS---GNSIFGSKPAPGTLGT--GLGAGFG 438 T++G FGN G +TN + FG G NTS G + S G L T G G G Sbjct: 1192 STSTGFSFGN------GLSTN-AGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLG 1244 Query: 439 TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480 T+ G G GG LGT A + G T+ GFG Sbjct: 1245 TSAGFGGGP---GTSTGFGGGLGTSAGFSGGLGTSA---GFG 1280 Score = 87.0 bits (214), Expect = 7e-17 Identities = 148/526 (28%), Positives = 214/526 (40%), Gaps = 87/526 (16%) Query: 16 GFGTTSTFGQNTGFGTTSGGAFGTSA--FGSSNNTGGLFGNSQTKP-GGLFGTSSFSQPA 72 GF ++ N G ++SGG G FG + +T F N+ + GG TSS A Sbjct: 732 GFSDGASISFN-GAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSA 790 Query: 73 TSTSTGFGFGTSTG---TANTLFGTASTGTSLFS-----------SQNNAFAQNKPTGFG 118 S S G TST A+ FG ++ FS S + F+ +GFG Sbjct: 791 ASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFG 850 Query: 119 NFGTSTSSGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTG----TTIKFNPPTGTDT 172 GT +++ G G +TS FGS T+ ++F + T+ G T++ F + Sbjct: 851 --GTLSTTAGFSGVL-STSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSG 907 Query: 173 MVKAGVSTNI--STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQV----GAGTTTG 226 +ST+I T S S+ AN G + G+ +T Sbjct: 908 SFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGA 967 Query: 227 LFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTG--FGTNPGGLFGQQNQQTTSL 284 FG + TS++ G +++T G A + GT +T FG +PG + T Sbjct: 968 GFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNT-- 1025 Query: 285 FSKPFGQATTTQNTGFSFGNTSTI----GQPST--------NTMGLFGV---TQASQPGG 329 + +G A +T NT F G ST G PST NT FG T AS G Sbjct: 1026 -NAGYGGAVST-NTDFG-GTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGA 1082 Query: 330 LFGTA-------TNTSTGTAFGTGTGLFGQTNTG--FGAVGSTLFGNNKLTTFGSSTTSA 380 + +A TN G AF T G G +T FG S G FG++ +++ Sbjct: 1083 VSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIG------FGAAPSTS 1136 Query: 381 PSFGTTSGG--LFGNKPTLTL--GTNTNTSNFGFGTNTSGNSIFGSKPAPG-----TLGT 431 SFG G FG P+ +L G+ +NT N FG S ++ F +P + T Sbjct: 1137 VSFGGAHGTSLCFGGAPSTSLCFGSASNT-NLCFGGPPSTSACFSGATSPSFCDGPSTST 1195 Query: 432 GLGAGFGTALGAGQASLFG---NNQPKIGGPLGTGAFGAPGFNTTT 474 G G G + AG FG N GG LGT A + G +T++ Sbjct: 1196 GFSFGNGLSTNAG----FGGGLNTSAGFGGGLGTSAGFSGGLSTSS 1237 Score = 67.0 bits (162), Expect = 8e-11 Identities = 77/256 (30%), Positives = 98/256 (38%), Gaps = 25/256 (9%) Query: 5 SFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG 64 S G FG G T + FG GG GTSA S GGL S GGL Sbjct: 1194 STGFSFGNG---LSTNAGFGGGLNTSAGFGGGLGTSAGFS----GGL-STSSGFDGGLGT 1245 Query: 65 TSSFSQ-PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGN-FGT 122 ++ F P TST G G GTS G + L +A G L +S GFG GT Sbjct: 1246 SAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSD----------GFGGGLGT 1295 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV--KAGVST 180 + S G GT+ S ++ G P++ T I F + T T + ST Sbjct: 1296 NASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTST 1355 Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVG--AGTTTGL-FGSSPATSSA 237 S+ I S + GP G G TG FG P+TS+ Sbjct: 1356 GFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAG 1415 Query: 238 TGLFSSSTTNSGFAYG 253 G ++S GF+YG Sbjct: 1416 FGSGAASLGACGFSYG 1431 Score = 33.9 bits (76), Expect = 0.73 Identities = 42/137 (30%), Positives = 49/137 (35%), Gaps = 39/137 (28%) Query: 3 NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTS-----AFGSSNNTG-GLFGNSQ 56 N SFG+ G G G ST + GFG+ +F FGS +NT G G Sbjct: 1296 NASFGSTLGTSAGFSGGLST---SDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPS 1352 Query: 57 TKPGGLFGTSSF--------------SQPATS---------------TSTGFGFGTSTGT 87 T G G SS S P+TS +TG GFG T Sbjct: 1353 TSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPST 1412 Query: 88 -ANTLFGTASTGTSLFS 103 A G AS G FS Sbjct: 1413 SAGFGSGAASLGACGFS 1429 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 95.1 bits (235), Expect = 3e-19 Identities = 118/446 (26%), Positives = 180/446 (40%), Gaps = 33/446 (7%) Query: 20 TSTFGQNTGFGTTSGGAF-----GTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATS 74 TST NTG S GA G+S S +T + G+S T G T+S +S Sbjct: 27 TST-SANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSS 85 Query: 75 TSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTN 134 G ST T N+ F T S+G S+ ++ ++ + + N +ST S G TN Sbjct: 86 -------GISTAT-NSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATN 137 Query: 135 TTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKE 194 + S+ S + + S T + +T N + T T A +TN + A Sbjct: 138 SDSSTTSSGASTATNSDSSTTSSEASTAT-NSESST-TSSGASTATNSESSTVSSRASTA 195 Query: 195 YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254 S+S N + GAGT T S+ ++ ++T S S+T S A Sbjct: 196 TNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTA 255 Query: 255 NKTAFGTSTTGFGT----NPGGLFGQQNQQTTSLFSKPFGQATTTQN----TGFSFGNTS 306 + T+++G GT + + T S S P A T N T S NT+ Sbjct: 256 TNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTA 315 Query: 307 TIGQPSTNTMGLFGVT--QASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTL 364 T ST + G T ++S TATN+ + T T +G TN+G S Sbjct: 316 TNSDSSTTSSGASTATNSESSTTSSGASTATNSESST---TSSGASTATNSGSSTTSS-- 370 Query: 365 FGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKP 424 G + T SST S+ + T+ + TN+ +S G +T+ NS + Sbjct: 371 -GTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTS 429 Query: 425 APGTLGTGLGAGFGTALGAGQASLFG 450 + T G+ T+ G+G A+L G Sbjct: 430 SGANTATNSGSSV-TSAGSGTAALTG 454 Score = 74.7 bits (182), Expect = 4e-13 Identities = 107/458 (23%), Positives = 178/458 (38%), Gaps = 59/458 (12%) Query: 3 NKSFGTPFGG---GTGGFGTTSTFGQNTGFGT-----TSGGAFGTSAFGSSNNTGGLFGN 54 N F T G T +T++ G +T + +SG + T++ S+ ++G + Sbjct: 92 NSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGA---S 148 Query: 55 SQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGT---ANTLFGTASTGTSLFSSQNNAFAQ 111 + T +S S S S+ G ST T ++T+ AST T+ SS ++ A Sbjct: 149 TATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGAS 208 Query: 112 NKP------------TGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTG 159 T + ++TSSG T + +S P + SS T++ G Sbjct: 209 TATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAG 268 Query: 160 TTIKFNPPT---GTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQ 216 T T G T+ + ST S + + S D G Sbjct: 269 TATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAS 328 Query: 217 NQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQ 276 + ++T G+S AT+S SSTT+SG + N G+STT GT+ Sbjct: 329 TATNSESSTTSSGASTATNS-----ESSTTSSGASTATNS---GSSTTSSGTSTA----- 375 Query: 277 QNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVT--QASQPGGLFGTA 334 N +++++ S T+ +T S +T+T + ST + G T ++S TA Sbjct: 376 TNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTA 435 Query: 335 TN-----TSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKL---TTFGSSTTSAPSFGTT 386 TN TS G+ TG+ +++ AV G + + + + + G Sbjct: 436 TNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGGSLVPWEIFLITLVSVVAAVGLF 495 Query: 387 SGGLFGNKPTLTLGTNTNTS-------NFGFGTNTSGN 417 +G F + +L+L NT+ N G G GN Sbjct: 496 AGLFFCVRNSLSLRNTFNTAVYHPHGLNHGLGPGPGGN 533 >gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] Length = 984 Score = 90.9 bits (224), Expect = 5e-18 Identities = 124/440 (28%), Positives = 182/440 (41%), Gaps = 73/440 (16%) Query: 85 TGTANTLFGTASTGTS---LFSSQNNAFAQNKPT-GFGNFGTSTSSGGLFGTTNTTSNPF 140 T TA G AS ++ + S+ + + +KP GFG S+SS + TTS Sbjct: 537 TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS-----VSTTTSTAT 591 Query: 141 GSTSGSLFGP-----SSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCI-TAMKE 194 ++ LFG +SFT A G+ +F P T +T ++T Q + TA+ Sbjct: 592 AASQPFLFGAPQASAASFTPA-MGSIFQFGKPPALPT------TTTVTTFSQSLHTAVPT 644 Query: 195 YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254 S S + G G+T L S+PATSS L S+T+ F Sbjct: 645 ATSSSAADFS---------------GFGST--LATSAPATSSQPTLTFSNTSTPTFNIPF 687 Query: 255 NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST-IGQPST 313 +A + G NP FG Q +KP + + F+FGN++ P+ Sbjct: 688 GSSAKSPLPSYPGANPQPAFGAAEGQPPGA-AKP--ALAPSFGSSFTFGNSAAPAAAPTP 744 Query: 314 NTMGLFGVTQASQPGGL---FGTATNTSTGT---------------AFGTGTGLF--GQT 353 + V A P + FG AT+++ G AFG T +F T Sbjct: 745 APPSMIKVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFFGAAT 804 Query: 354 NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTS----GGLFGNKPTLTLGTNTNTSNFG 409 ++GFGA T + + FGS+T S +FG ++ G FG T G++T T F Sbjct: 805 SSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGIN-VATPGSSTTTGAFS 863 Query: 410 FGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFG--- 466 FG SG++ + A G LG + A S ++P GG T FG Sbjct: 864 FGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGG-TATPTFGLNT 922 Query: 467 -APGFNTTTATLGFGAPQAP 485 APG T+ ++L FGA AP Sbjct: 923 PAPGVGTSGSSLSFGASSAP 942 Score = 53.9 bits (128), Expect = 7e-07 Identities = 104/439 (23%), Positives = 150/439 (34%), Gaps = 96/439 (21%) Query: 6 FGTPFGGG---TGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKP--G 60 FG P T G+ FG+ TT+ + F S +T S + Sbjct: 599 FGAPQASAASFTPAMGSIFQFGKPPALPTTTT----VTTFSQSLHTAVPTATSSSAADFS 654 Query: 61 GLFGTSSFSQPATSTSTGFGFG-TSTGTANTLFGTASTG---TSLFSSQNNAF--AQNKP 114 G T + S PATS+ F TST T N FG+++ + ++ AF A+ +P Sbjct: 655 GFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQP 714 Query: 115 TGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV 174 G + S G F N+ + T PS P +P G T Sbjct: 715 PGAAKPALAPSFGSSFTFGNSAAPAAAPTPAP---PSMIKVVPAYVPTPIHPIFGGATHS 771 Query: 175 KAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPAT 234 G+ S GA + S PA Sbjct: 772 AFGLKATASA----------------------------------FGAPAS-----SQPAF 792 Query: 235 SSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT 294 +T +F + T+SGF + G+S++ FG+ T S F+ FG + Sbjct: 793 GGSTAVFFGAATSSGFGATTQTASSGSSSSVFGST-----------TPSPFT--FGGSAA 839 Query: 295 TQNTGFSFG-NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQT 353 +G SFG N +T G +T FG Q+ +T TST A G G G T Sbjct: 840 PAGSG-SFGINVATPGSSTTTGAFSFGAGQSG--------STATSTPFAGGLGQNALGTT 890 Query: 354 --------NTGFGAVGSTLFGNNKLTTFGSSTT--------SAPSFGTTSGGLFGNKPTL 397 N +FG TFG +T S+ SFG +S G Sbjct: 891 GQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVA 950 Query: 398 TLGTNTNTSNFGFGTNTSG 416 G+ + + G G+ T G Sbjct: 951 PFGSAALSFSIGAGSKTPG 969 Score = 52.4 bits (124), Expect = 2e-06 Identities = 66/196 (33%), Positives = 87/196 (44%), Gaps = 37/196 (18%) Query: 5 SFGTP------FGGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNS 55 +FG P FGG T G T+S FG T T S G+ +S FGS+ + FG S Sbjct: 781 AFGAPASSQPAFGGSTAVFFGAATSSGFGATTQ--TASSGS-SSSVFGSTTPSPFTFGGS 837 Query: 56 QTKPG-GLFGTSSFSQPATSTSTG---FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ 111 G G FG + + P +ST+TG FG G S TA + G + + Q Sbjct: 838 AAPAGSGSFGIN-VATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGTT----GQ 892 Query: 112 NKPTGFGNFGTSTSSGGLFGTTNT------TSNPFGSTSGS--LFGPSSFTA------AP 157 + P F N ++T S +FG T T T P TSGS FG SS A AP Sbjct: 893 STPFAF-NVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAP 951 Query: 158 TGT-TIKFNPPTGTDT 172 G+ + F+ G+ T Sbjct: 952 FGSAALSFSIGAGSKT 967 >gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo sapiens] Length = 834 Score = 89.7 bits (221), Expect = 1e-17 Identities = 128/447 (28%), Positives = 184/447 (41%), Gaps = 86/447 (19%) Query: 85 TGTANTLFGTASTGTS---LFSSQNNAFAQNKPT-GFGNFGTSTSSGGLFGTTNTTSNPF 140 T TA G AS ++ + S+ + + +KP GFG S+SS + TTS Sbjct: 386 TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS-----VSTTTSTAT 440 Query: 141 GSTSGSLFGP-----SSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCI-TAMKE 194 ++ LFG +SFT A G+ +F P T +T ++T Q + TA+ Sbjct: 441 AASQPFLFGAPQASAASFTPA-MGSIFQFGKPPALPT------TTTVTTFSQSLPTAVPT 493 Query: 195 YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254 S S + G G+T L S+PATSS L S+T+ F Sbjct: 494 ATSSSAADFS---------------GFGST--LATSAPATSSQPTLTFSNTSTPTFNIPF 536 Query: 255 NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST-IGQPST 313 +A + G NP FG Q +KP T + + F+FGN++ P+ Sbjct: 537 GSSAKSPLPSYPGANPQPAFGAAEGQPPGA-AKP--ALTPSFGSSFTFGNSAAPAAAPTP 593 Query: 314 NTMGLFGVTQASQPGGL---FGTATNTSTGT---------------AFGTGTGLFG---Q 352 + + A P + FG AT+++ G AFG T +F Sbjct: 594 APPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAA 653 Query: 353 TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTS----GGLFGNKPTLTLGTNTNTSNF 408 T++GFGA T + + FGS+T S +FG ++ G FG T G++ T F Sbjct: 654 TSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGIN-VATPGSSATTGAF 712 Query: 409 GFGTNTSGNSIFGSKPAPGTLG------TGLGAGFGTALGAGQASLFGNNQPKIGGPLGT 462 FG SG S S P G LG TG F +G+ S +P GG T Sbjct: 713 SFGAGQSG-STATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTES-----KPVFGG-TAT 765 Query: 463 GAFG----APGFNTTTATLGFGAPQAP 485 FG APG T+ ++L FGA AP Sbjct: 766 PTFGLNTPAPGVGTSGSSLSFGASSAP 792 Score = 75.1 bits (183), Expect = 3e-13 Identities = 120/484 (24%), Positives = 176/484 (36%), Gaps = 75/484 (15%) Query: 69 SQPATSTSTGFGFGT-STGTANTLFGTASTGTSLFSSQNNAFAQNK-----PTGFGNFGT 122 S P+ + F FGT +T ++ AS+ + +F A +++ P G T Sbjct: 278 SAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSAT 337 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSF-------------TAAPTGTTIKF----N 165 + SS L TT+TT+ F S+ P+S APT T F + Sbjct: 338 APSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLAS 397 Query: 166 PPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRK---GPQNQVGAG 222 + + A ST+ ++K + S S+ A++ G A Sbjct: 398 ATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAAS 457 Query: 223 TTTGL-----FGSSPA--TSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFG 275 T + FG PA T++ FS S A ++ +GFG+ Sbjct: 458 FTPAMGSIFQFGKPPALPTTTTVTTFSQSLPT---AVPTATSSSAADFSGFGSTLATSAP 514 Query: 276 QQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS---TNTMGLFGVTQASQPGGLFG 332 + Q T FS T+T FG+++ PS N FG + QP G Sbjct: 515 ATSSQPTLTFSN-----TSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE-GQPPGAAK 568 Query: 333 TATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG 392 A S G++F FG + A K+ T P+FG + FG Sbjct: 569 PALTPSFGSSF-----TFGNSAAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFG 623 Query: 393 NKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFG----TALGAGQASL 448 K T + FG S FG A + G +GFG TA +S+ Sbjct: 624 LKATAS----------AFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSV 673 Query: 449 FGNNQPK---IGG---PLGTGAFG----APGFNTTTATLGFGAPQA-PVALTDPNASAAQ 497 FG+ P GG P G+G+FG PG + TT FGA Q+ A + P A Sbjct: 674 FGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLG 733 Query: 498 QAVL 501 Q L Sbjct: 734 QNAL 737 Score = 55.1 bits (131), Expect = 3e-07 Identities = 110/437 (25%), Positives = 152/437 (34%), Gaps = 91/437 (20%) Query: 6 FGTPFGGG---TGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62 FG P T G+ FG+ TT+ + + ++ T +S G Sbjct: 448 FGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTAT--SSSAADFSGF 505 Query: 63 FGTSSFSQPATSTSTGFGFG-TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFG 121 T + S PATS+ F TST T N FG S+ S S A N FG Sbjct: 506 GSTLATSAPATSSQPTLTFSNTSTPTFNIPFG--SSAKSPLPSYPGA---NPQPAFG--- 557 Query: 122 TSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181 + G G P +S + ++ AAPT P +V A V T Sbjct: 558 --AAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPA------PPSMIKIVPAHVPTP 609 Query: 182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFG----SSPATSSA 237 I T + G T FG S PA + Sbjct: 610 IQPTFGGAT-------------------------HSAFGLKATASAFGAPASSQPAFGGS 644 Query: 238 TGLFS-SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQ 296 T +FS + T+SGF + G+S++ FG+ T S F+ FG + Sbjct: 645 TAVFSFGAATSSGFGATTQTASSGSSSSVFGST-----------TPSPFT--FGGSAAPA 691 Query: 297 NTGFSFG-NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQT-- 353 +G SFG N +T G +T FG Q+ +T TST A G G G T Sbjct: 692 GSG-SFGINVATPGSSATTGAFSFGAGQSG--------STATSTPFAGGLGQNALGTTGQ 742 Query: 354 ------NTGFGAVGSTLFGNNKLTTFGSSTT--------SAPSFGTTSGGLFGNKPTLTL 399 N G +FG TFG +T S+ SFG +S G Sbjct: 743 STPFAFNVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPF 802 Query: 400 GTNTNTSNFGFGTNTSG 416 G+ + + G G+ T G Sbjct: 803 GSAAPSFSIGAGSKTLG 819 Score = 46.2 bits (108), Expect = 1e-04 Identities = 61/199 (30%), Positives = 84/199 (42%), Gaps = 40/199 (20%) Query: 5 SFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFG----TSAFGSSNNTGG-------LFG 53 +FG P G+T+ F FG + FG T++ GSS++ G FG Sbjct: 630 AFGAPASSQPAFGGSTAVFS----FGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFG 685 Query: 54 NSQTKPG-GLFGTSSFSQPATSTSTG---FGFGTSTGTANTLFGTASTGTSLFSSQNNAF 109 S G G FG + + P +S +TG FG G S TA + G + + Sbjct: 686 GSAAPAGSGSFGI-NVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGTT---- 740 Query: 110 AQNKPTGFGNFGTSTSSGGLFGTTNT------TSNPFGSTSGS--LFGPSSFTA------ 155 Q+ P F N G++T S +FG T T T P TSGS FG SS A Sbjct: 741 GQSTPFAF-NVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGV 799 Query: 156 APTGTTI-KFNPPTGTDTM 173 AP G+ F+ G+ T+ Sbjct: 800 APFGSAAPSFSIGAGSKTL 818 >gi|62122917 filaggrin family member 2 [Homo sapiens] Length = 2391 Score = 87.8 bits (216), Expect = 4e-17 Identities = 132/499 (26%), Positives = 217/499 (43%), Gaps = 83/499 (16%) Query: 10 FGGGTG---GFGTT-STFGQNTGFG---TTSG-GAFGTSAFGSSNNTG-GLFGNSQTKPG 60 +G G+G GFG S GQ++GFG + SG ++G + GSS ++G G G+ QT Sbjct: 583 YGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGF 642 Query: 61 GLFGTSSFSQPATSTSTGFG-FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPT---- 115 G G+ S S STGFG +G+ +G ++ FG +G S Q++ F Q++ Sbjct: 643 GQHGSGS------SQSTGFGQYGSGSGQSSG-FGQHVSG----SGQSSGFGQHESRSGHS 691 Query: 116 --GFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT 172 G FG+S SSG G G+++ ++ FG S SSF +G+ +G Sbjct: 692 SYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGS----GQSSGFGQ 747 Query: 173 MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGL--FGS 230 ++ +H+ + Y S + Y Q G+ T+G GS Sbjct: 748 HGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGY--------GQHGSRQTSGFGQHGS 799 Query: 231 SPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFG 290 + S+ G + S + S +GQ+ + G S +GFG + + +Q + Sbjct: 800 GSSQSTGFGQYGSGSGQSA-GFGQHGSGSGQS-SGFGQHE----SRSHQSSYGQHGSGSS 853 Query: 291 QATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLF 350 Q++ G S G TS GQ +++ G G G+ + S+G F Sbjct: 854 QSSGYGQHGSSSGQTSGFGQHRSSSGQYSGF-------GQHGSGSGQSSG---------F 897 Query: 351 GQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF 410 GQ TG G FG ++ + SS S + S G +G +++ FGF Sbjct: 898 GQHGTGSGQYSG--FGQHESRSHQSSYGQHGSGSSQSSG-YGQH------GSSSGQTFGF 948 Query: 411 GTNTSGNSIFGSKPAPGTLGTGLGAGFGT-ALGAGQASLFGNNQPKIG----GPLGTGAF 465 G + SG+ G+ G+G +GFG G+G++S FG ++ + G G+G+ Sbjct: 949 GQHRSGSGQSSGFGQHGS-GSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSS 1007 Query: 466 GAPGF----NTTTATLGFG 480 + G+ +++ T GFG Sbjct: 1008 QSSGYGQHGSSSGQTTGFG 1026 Score = 85.5 bits (210), Expect = 2e-16 Identities = 136/501 (27%), Positives = 217/501 (43%), Gaps = 57/501 (11%) Query: 12 GGTGGFGTT-STFGQNTGFGTTSGGAFGTSAFGSSNNTGGL---FGNSQTKPGGLFGTSS 67 G T GFG S GQ++GFG G+ +S FG + G FG + G G Sbjct: 474 GKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQ 533 Query: 68 FSQPATSTSTG-FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTST-- 124 + +S G G G+S + +G+ T + + TGFG +G+ + Sbjct: 534 HESRSRQSSYGQHGSGSSQSSGYGQYGSRETS----GFGQHGLGSGQSTGFGQYGSGSGQ 589 Query: 125 SSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183 SSG G G+ + S+ FG S G SS+ +G++ + + + +G + S Sbjct: 590 SSGFGQHGSGSGQSSGFGQHE-SRSGQSSYGQHSSGSS-QSSGYGQHGSRQTSGFGQHGS 647 Query: 184 TKHQCITAMKEYESKSLEELRLEDY-----QANRKGPQNQVGAGTTTGLFGSSPATSSAT 238 Q T +Y S S + + Q++ G ++ G G + SS Sbjct: 648 GSSQS-TGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGY 706 Query: 239 GLF-SSSTTNSGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQAT 293 G SSS SGF GQ++ + G S++ G G+ FGQ + S FGQ Sbjct: 707 GQHGSSSGQTSGF--GQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQ--SSGFGQHE 762 Query: 294 TTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA-FGTGTGL--- 349 + S+G S+ G ++ G G Q S G G+ ++ STG +G+G+G Sbjct: 763 SRSGQS-SYGQHSS-GSSQSSGYGQHGSRQTS-GFGQHGSGSSQSTGFGQYGSGSGQSAG 819 Query: 350 FGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFG 409 FGQ +G G S+ FG ++ + SS S + S G +G + ++ TS FG Sbjct: 820 FGQHGSGSGQ--SSGFGQHESRSHQSSYGQHGSGSSQSSG-YGQHGS----SSGQTSGFG 872 Query: 410 FGTNTSGN-SIFGSKPAPGTLGTGLGAGFGT-ALGAGQASLFGNNQPKIG----GPLGTG 463 ++SG S FG + G+G +GFG G+GQ S FG ++ + G G+G Sbjct: 873 QHRSSSGQYSGFGQHGS----GSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSG 928 Query: 464 AFGAPGF----NTTTATLGFG 480 + + G+ +++ T GFG Sbjct: 929 SSQSSGYGQHGSSSGQTFGFG 949 Score = 79.3 bits (194), Expect = 2e-14 Identities = 116/495 (23%), Positives = 197/495 (39%), Gaps = 51/495 (10%) Query: 21 STFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQ--PATSTSTG 78 ST Q+ G+ + TS FG + G G +S F Q + S+G Sbjct: 458 STSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSG 517 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSG----GLFGTTN 134 FG S ++ FG + + S + ++ +G+G +G+ +SG GL + Sbjct: 518 FGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQS 577 Query: 135 TTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKE 194 T +GS SG G G+ + +G + S Q ++ + Sbjct: 578 TGFGQYGSGSGQSSGFGQH---------------GSGSGQSSGFGQHESRSGQ--SSYGQ 620 Query: 195 YESKSLEELRLEDYQANRKGPQNQVGAG----TTTGLFGSSPATSSATGL-FSSSTTNSG 249 + S S + + + + Q G+G T G +GS SS G S S +SG Sbjct: 621 HSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSG 680 Query: 250 FAYGQNKTAFGTST---TGFGTNPGGLFGQQNQQT--TSLFSK---PFGQATTTQNTGFS 301 F GQ+++ G S+ GFG++ +GQ + TS F + GQ+++ G Sbjct: 681 F--GQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSG 738 Query: 302 FGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNT-GFGAV 360 G +S GQ + + G Q G + S+G++ +G G G T GFG Sbjct: 739 SGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQH-SSGSSQSSGYGQHGSRQTSGFGQH 797 Query: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFG-FGTNTSGNSI 419 GS + +GS + + FG G + + ++ S++G G+ +S +S Sbjct: 798 GSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSG 857 Query: 420 FGSKPAPGTLGTGLG---------AGFGT-ALGAGQASLFGNNQPKIGGPLGTGAFGAPG 469 +G + +G G +GFG G+GQ+S FG + G G G + Sbjct: 858 YGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRS 917 Query: 470 FNTTTATLGFGAPQA 484 ++ G G+ Q+ Sbjct: 918 HQSSYGQHGSGSSQS 932 Score = 77.4 bits (189), Expect = 6e-14 Identities = 127/539 (23%), Positives = 213/539 (39%), Gaps = 74/539 (13%) Query: 13 GTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+GG Q+ G G+ G + SS+N F G ++SF Q Sbjct: 384 GSGG-------SQSCSNGQHEYGSCGRFSNSSSSNE---FSKCDQYGSGSSQSTSFEQHG 433 Query: 73 TSTSTGFGFGTST-GTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFG 131 T S GF G+ T ST + + + K +GFG G+ + FG Sbjct: 434 TGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFG 493 Query: 132 TTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 + S G +SG FG + + + +G + G + S Q ++ Sbjct: 494 QCGSGS---GQSSG--FGQHGSVSGQSSGFGQHGSVSGQSS----GFGQHESRSRQ--SS 542 Query: 192 MKEYESKSLEELRLEDYQANRKGP--QNQVGAGTTTGL--FGSSPATSSATGLFSSSTTN 247 ++ S S + Y + Q+ +G+G +TG +GS SS G S + Sbjct: 543 YGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQ 602 Query: 248 SGFAYGQNKTAFGTSTTG---FGTNPGGLFGQQNQQTTSLFSKPFGQ--ATTTQNTGFS- 301 S +GQ+++ G S+ G G++ +GQ + TS FGQ + ++Q+TGF Sbjct: 603 SS-GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTS----GFGQHGSGSSQSTGFGQ 657 Query: 302 FGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVG 361 +G+ S GQ S + G Q+S FG + S +++G G ++G+G G Sbjct: 658 YGSGS--GQSSGFGQHVSGSGQSSG----FGQHESRSGHSSYGQH-GFGSSQSSGYGQHG 710 Query: 362 STL-----FGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSG 416 S+ FG ++L++ SS+ G+ FG + + +S FG + SG Sbjct: 711 SSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGS----GSGQSSGFGQHESRSG 766 Query: 417 NSIFGSKPAPGTLGTGLG-------AGFGT--------------ALGAGQASLFGNNQPK 455 S +G + + +G G +GFG G+GQ++ FG + Sbjct: 767 QSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSG 826 Query: 456 IGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFG 514 G G G + ++ G G+ Q+ ++S Q +S YS FG Sbjct: 827 SGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFG 885 Score = 67.0 bits (162), Expect = 8e-11 Identities = 114/498 (22%), Positives = 195/498 (39%), Gaps = 99/498 (19%) Query: 3 NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62 ++S + +G G +S +GQ+ G++SG TS FG ++ G + Sbjct: 838 SRSHQSSYGQHGSGSSQSSGYGQH---GSSSGQ---TSGFGQHRSSSGQY---------- 881 Query: 63 FGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT 122 S F Q G G G S+G FG TG+ +S +++ + +G G+ Sbjct: 882 ---SGFGQ------HGSGSGQSSG-----FGQHGTGSGQYSGFGQHESRSHQSSYGQHGS 927 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +S +G GS+SG FG + +G + F G+ + +G + Sbjct: 928 GSSQSSGYG-------QHGSSSGQTFGFGQHRSG-SGQSSGFG-QHGSGSGQSSGFGQHE 978 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF- 241 S + + ++ES+S + +Y + G G G GSS ++ G Sbjct: 979 SGSGKS-SGFGQHESRSSQ----SNYGQHGSGSSQSSGYGQ----HGSSSGQTTGFGQHR 1029 Query: 242 SSSTTNSGFAY----GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQ--ATTT 295 SSS SGF + FG TG G + G FGQ ++ +GQ + ++ Sbjct: 1030 SSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSG--FGQYESRSR---QSSYGQHGSGSS 1084 Query: 296 QNTGF-----SFGNTSTIGQ-----PSTNTMGLFGVTQASQPG-GLFGTATNTSTGTA-- 342 Q++G+ + G TS GQ ++ G +G G G G+ T S+G A Sbjct: 1085 QSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQH 1144 Query: 343 -FGTGTGLFGQTNTG---FGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 + +G +GQ TG G G+ T+FG + + +F ++ + + Sbjct: 1145 EYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDS----- 1199 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGG 458 G +T +G G+ S TGLG G + +G +++ G + G Sbjct: 1200 -GQSTGFGQYGSGSGQS---------------TGLGQGESQQVESG-STVHGRQETTHGQ 1242 Query: 459 PLGTGAFGAPGFNTTTAT 476 + T G +T T Sbjct: 1243 TINTTRHSQSGQGQSTQT 1260 Score = 62.0 bits (149), Expect = 3e-09 Identities = 111/452 (24%), Positives = 185/452 (40%), Gaps = 67/452 (14%) Query: 69 SQPATSTSTGFGFGT-STGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSG 127 S P + + + G+G G G TG SSQ++ Q +G+ G+ + S Sbjct: 343 SNPCSQSYSQRGYGARENGQPQNCGGQWRTG----SSQSSCCGQ-----YGSGGSQSCSN 393 Query: 128 GL--FGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185 G +G+ SN S+S + F + + + F GT +G ++ Sbjct: 394 GQHEYGSCGRFSN---SSSSNEFSKCDQYGSGSSQSTSFEQH-GTGLSQSSGFEQHVCGS 449 Query: 186 HQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSST 245 Q ++ES S + L + + ++ G + G GS SS G S + Sbjct: 450 GQ---TCGQHESTSSQSLGYDQHGSSS-------GKTSGFGQHGSGSGQSSGFGQCGSGS 499 Query: 246 TNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNT 305 S +GQ+ + G S+ GFG + G + GQ S FGQ + S+G Sbjct: 500 GQSS-GFGQHGSVSGQSS-GFGQH-GSVSGQ---------SSGFGQHESRSRQS-SYGQH 546 Query: 306 STIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA-FGTGTGLFGQTNTGFGAVGSTL 364 + G ++ G +G + S G G + STG +G+G+G ++GFG GS Sbjct: 547 GS-GSSQSSGYGQYGSRETSG-FGQHGLGSGQSTGFGQYGSGSG----QSSGFGQHGS-- 598 Query: 365 FGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGS 422 G+ + + FG S + S+G S G + + G + + GFG + SG+S Sbjct: 599 -GSGQSSGFGQHESRSGQSSYGQHSSG---SSQSSGYGQHGSRQTSGFGQHGSGSS---- 650 Query: 423 KPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAP 482 TG G +G+ G+GQ+S FG + G G G + +++ GFG+ Sbjct: 651 ------QSTGFGQ-YGS--GSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSS 701 Query: 483 QAPVALTDPNASAAQQAVLQQHINSLTYSPFG 514 Q+ ++S Q ++S S FG Sbjct: 702 QSSGYGQHGSSSGQTSGFGQHELSSGQSSSFG 733 Score = 54.3 bits (129), Expect = 5e-07 Identities = 91/401 (22%), Positives = 154/401 (38%), Gaps = 44/401 (10%) Query: 7 GTPFGGGTGGFGTTSTFGQNTGFGTTSG----GAFGTSAFGSSNNTGGLFGNSQTKPGGL 62 G+ G G GT S GQ++GFG ++G GSS ++G +G + G Sbjct: 1044 GSDQSSGFGQHGTGS--GQSSGFGQYESRSRQSSYGQHGSGSSQSSG--YGQHGSNSGQ- 1098 Query: 63 FGTSSFSQ--PATSTSTGFG-FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK----PT 115 TS F Q P + S+GFG +G+ +G ++ FG +GT +++ FAQ++ + Sbjct: 1099 --TSGFGQHRPGSGQSSGFGQYGSGSGQSSG-FGQHGSGT----GKSSGFAQHEYRSGQS 1151 Query: 116 GFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTA-----APTGTTI---KFNPP 167 +G GT +S G + S P S + G +F++ + +G + ++ Sbjct: 1152 SYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSG 1211 Query: 168 TGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGL 227 +G T + G S + + T E+ + + + + +G Q G+ T Sbjct: 1212 SGQSTGLGQGESQQVESGS---TVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRR 1268 Query: 228 FGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSK 287 S S + S +S + Q + + S + G GQ+ T S Sbjct: 1269 RSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHS- 1327 Query: 288 PFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVT----QASQPGGLFGTATNTSTGTAF 343 G +TQ + G +T++ GV+ Q G+ S T Sbjct: 1328 --GHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVH 1385 Query: 344 GTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFG 384 +GQT A G G+ + T GS TT G Sbjct: 1386 ERHETTYGQTGE---ATGHGHSGHGQSTQRGSRTTGRRGSG 1423 Score = 38.5 bits (88), Expect = 0.030 Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 12/170 (7%) Query: 214 GPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGL 273 G Q G+ TT S + G S T+SG +GQ ++ G S + G + Sbjct: 1711 GLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTI 1770 Query: 274 FGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGT 333 GQ T S G +TQ + G S+ +++ G G +Q G Sbjct: 1771 HGQTGDTTRHAHS---GHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRG---- 1823 Query: 334 ATNTSTGTAFGTGTGLFGQTN-TGFGAVGST----LFGNNKLTTFGSSTT 378 T+ G+ G + + + T G G T G+ + T GSSTT Sbjct: 1824 HTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTT 1873 Score = 37.0 bits (84), Expect = 0.086 Identities = 101/422 (23%), Positives = 162/422 (38%), Gaps = 63/422 (14%) Query: 7 GTPFGGGTGGFGTTSTFGQNTGFG--TTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG 64 G P G T G+ +T + +G + S G G S S +T G G+ + G Sbjct: 1933 GHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVS-HTHSGHTHGQAGSHYPESGSSVH 1991 Query: 65 T---SSFSQPATSTSTGF-GFGTSTGTANTLFGTASTGTSLFS-SQNNAFAQNKPTGFGN 119 ++ Q A +T G G G ST + G ++G S +S S+ ++ + +G + Sbjct: 1992 ERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAH 2051 Query: 120 ------FGTSTSS-----GGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPT 168 G S SS G G T T+ S G S TA G+ Sbjct: 2052 GQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGS----GHSE 2107 Query: 169 GTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELR----------LEDYQANRKGPQNQ 218 +D+ V +GVS S + ES S R + + G Q Sbjct: 2108 SSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQ 2167 Query: 219 VGAGTTTGLFGSSPATSSATGLFS-SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQ 277 G+ TTG SS + SS + + S +S T+SG + Q + G S G++ G G Sbjct: 2168 TGS-RTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQS----GSSGHGRQGTT 2222 Query: 278 NQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNT 337 + QT TT++ + +G ++ G +T G G +++S + ++T Sbjct: 2223 HGQT----------GDTTRHAHYGYGQSTQRGSRTTGRRG-SGHSESSD-SEVHSWGSHT 2270 Query: 338 STGTAFG--------TGTGLFGQTNTGFGAVGSTL----FGNNKLTTFGSSTTSAPSFGT 385 +G G G+ + G+ T G G T G + T GS ++ A F + Sbjct: 2271 HSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQS 2330 Query: 386 TS 387 S Sbjct: 2331 HS 2332 Score = 32.0 bits (71), Expect = 2.8 Identities = 47/173 (27%), Positives = 68/173 (39%), Gaps = 18/173 (10%) Query: 214 GPQNQVGAGTTTGLFGSSPATSSATGLFSS-STTNSGFAYGQNKTAFGTSTTGFGTNPGG 272 G Q G+ +TTG GS + SS + + S S T+SG +GQ+ + G S + Sbjct: 1484 GKSTQRGS-STTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRI 1542 Query: 273 LFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT-MGLFGVTQASQPGGLF 331 GQ T +S G TTQ + G T ST++ + G + + Sbjct: 1543 THGQTGDTTRHSYS---GHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTY 1599 Query: 332 GTATNTSTGTAF------GTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378 G A + F GT G G T G + G+ + T GS TT Sbjct: 1600 GQAGSQHEEPEFTVHERHGTTHGQIGDT------TGHSHSGHGQSTQRGSRTT 1646 >gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] Length = 987 Score = 87.4 bits (215), Expect = 6e-17 Identities = 128/449 (28%), Positives = 183/449 (40%), Gaps = 88/449 (19%) Query: 85 TGTANTLFGTASTGTS---LFSSQNNAFAQNKPT-GFGNFGTSTSSGGLFGTTNTTSNPF 140 T TA G AS ++ + S+ + + +KP GFG S+SS + TTS Sbjct: 537 TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS-----VSTTTSTAT 591 Query: 141 GSTSGSLFGP-----SSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCI-TAMKE 194 ++ LFG +SFT A G+ +F P T +T ++T Q + TA+ Sbjct: 592 AASQPFLFGAPQASAASFTPA-MGSIFQFGKPPALPT------TTTVTTFSQSLPTAVPT 644 Query: 195 YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254 S S + G G+T L S+PATSS L S+T+ F Sbjct: 645 ATSSSAADFS---------------GFGST--LATSAPATSSQPTLTFSNTSTPTFNIPF 687 Query: 255 NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ---P 311 +A + G NP FG Q +KP T + + F+FGN++ P Sbjct: 688 GSSAKSPLPSYPGANPQPAFGAAEGQPPGA-AKP--ALTPSFGSSFTFGNSAAPAPATAP 744 Query: 312 STNTMGLFGVTQASQPGGL---FGTATNTSTGT---------------AFGTGTGLFG-- 351 + + A P + FG AT+++ G AFG T +F Sbjct: 745 TPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFG 804 Query: 352 -QTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTS----GGLFGNKPTLTLGTNTNTS 406 T++GFGA T + + FGS+T S +FG ++ G FG T G++ T Sbjct: 805 AATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGIN-VATPGSSATTG 863 Query: 407 NFGFGTNTSGNSIFGSKPAPGTLG------TGLGAGFGTALGAGQASLFGNNQPKIGGPL 460 F FG SG S S P G LG TG F +G+ S +P GG Sbjct: 864 AFSFGAGQSG-STATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTES-----KPVFGG-T 916 Query: 461 GTGAFG----APGFNTTTATLGFGAPQAP 485 T FG APG T+ ++L FGA AP Sbjct: 917 ATPTFGQNTPAPGVGTSGSSLSFGASSAP 945 Score = 75.5 bits (184), Expect = 2e-13 Identities = 117/467 (25%), Positives = 172/467 (36%), Gaps = 74/467 (15%) Query: 69 SQPATSTSTGFGFGT-STGTANTLFGTASTGTSLFSSQNNAFAQNK-----PTGFGNFGT 122 S P+ + F FGT +T ++ AS+ + +F A +++ P G T Sbjct: 429 SAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTAT 488 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSF-------------TAAPTGTTIKF----N 165 + SS L TT+TT+ F S+ P+S APT T F + Sbjct: 489 APSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLAS 548 Query: 166 PPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRK---GPQNQVGAG 222 + + A ST+ ++K + S S+ A++ G A Sbjct: 549 ATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAAS 608 Query: 223 TTTGL-----FGSSPA--TSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFG 275 T + FG PA T++ FS S A ++ +GFG+ Sbjct: 609 FTPAMGSIFQFGKPPALPTTTTVTTFSQSLPT---AVPTATSSSAADFSGFGSTLATSAP 665 Query: 276 QQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS---TNTMGLFGVTQASQPGGLFG 332 + Q T FS T+T FG+++ PS N FG + QP G Sbjct: 666 ATSSQPTLTFSN-----TSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE-GQPPGAAK 719 Query: 333 TATNTSTGTAFGTGTGLFGQTNTG-FGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLF 391 A S G++F G T A ST+ K+ T P+FG + F Sbjct: 720 PALTPSFGSSFTFGNSAAPAPATAPTPAPASTI----KIVPAHVPTPIQPTFGGATHSAF 775 Query: 392 GNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFG----TALGAGQAS 447 G K T + FG S FG A + G +GFG TA +S Sbjct: 776 GLKATAS----------AFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSS 825 Query: 448 LFGNNQPK---IGG---PLGTGAFG----APGFNTTTATLGFGAPQA 484 +FG+ P GG P G+G+FG PG + TT FGA Q+ Sbjct: 826 VFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQS 872 Score = 60.8 bits (146), Expect = 6e-09 Identities = 115/428 (26%), Positives = 157/428 (36%), Gaps = 84/428 (19%) Query: 6 FGTPFGGG---TGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62 FG P T G+ FG+ TT+ + + ++ T +S G Sbjct: 599 FGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTAT--SSSAADFSGF 656 Query: 63 FGTSSFSQPATSTSTGFGFG-TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFG 121 T + S PATS+ F TST T N FG S+ S S A N FG Sbjct: 657 GSTLATSAPATSSQPTLTFSNTSTPTFNIPFG--SSAKSPLPSYPGA---NPQPAFG--- 708 Query: 122 TSTSSGGLFGTTNTTSNP-FGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180 + G G P FGS+ FG S AAP T P T +V A V T Sbjct: 709 --AAEGQPPGAAKPALTPSFGSSF--TFGNS---AAPAPATAPTPAPASTIKIVPAHVPT 761 Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFG----SSPATSS 236 I T + G T FG S PA Sbjct: 762 PIQPTFGGAT-------------------------HSAFGLKATASAFGAPASSQPAFGG 796 Query: 237 ATGLFS-SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTT 295 +T +FS + T+SGF + G+S++ FG+ T S F+ FG + Sbjct: 797 STAVFSFGAATSSGFGATTQTASSGSSSSVFGST-----------TPSPFT--FGGSAAP 843 Query: 296 QNTGFSFG-NTSTIGQPSTNTMGLFGVTQASQP-------GGLFGTATNTS-TGTAFGTG 346 +G SFG N +T G +T FG Q+ GGL A T+ T F Sbjct: 844 AGSG-SFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFN 902 Query: 347 TGLFGQTNTGFGAVGSTLFGNNK----LTTFGSS----TTSAPSFGTTSGGLFGN-KPTL 397 G ++ FG + FG N + T GSS +SAP+ G G FG+ P+ Sbjct: 903 VGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAPSF 962 Query: 398 TLGTNTNT 405 ++G + T Sbjct: 963 SIGAGSKT 970 Score = 60.5 bits (145), Expect = 7e-09 Identities = 128/522 (24%), Positives = 170/522 (32%), Gaps = 101/522 (19%) Query: 33 SGGAFGTSAFGSSNNTGGL--FGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANT 90 S GA T A L G SQ+ P GL + SF +T G S A Sbjct: 351 SAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATD 410 Query: 91 LFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN----PFGSTSGS 146 + A KP + LFGT NT+ + P S++ Sbjct: 411 TKAPPTL---------QAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASP 461 Query: 147 LFGPSSFTAAPTGTTIKFNPP-------TGTDTMVKAGVSTNISTKHQCITAMKEYESKS 199 +F P FTA P PP + + + ST T ++M S Sbjct: 462 MFKPI-FTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVP 520 Query: 200 LEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAF 259 L + P TT LF + +SA +S++ ++ A +K AF Sbjct: 521 LPAPFFKQTTTPATAPT------TTAPLFTGLASATSAVAPITSASPSTDSA---SKPAF 571 Query: 260 GTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLF 319 G FG N + TTS T + F FG T MG Sbjct: 572 G-----FGIN--SVSSSSVSTTTS--------TATAASQPFLFGAPQASAASFTPAMG-- 614 Query: 320 GVTQASQPGGLFGTATNT----STGTAFGTGTGLFGQTNTGFGAVGST-----------L 364 + Q +P L T T T S TA T T +GFG+ +T Sbjct: 615 SIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLT 674 Query: 365 FGNNKLTTF----GSSTTSA----------PSFGTTSGGLFGN-KPTLTLGTNTNTSNFG 409 F N TF GSS S P+FG G G KP LT S+F Sbjct: 675 FSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFG---SSFT 731 Query: 410 FGTNTSGNSIFGSKPAPG----------------TLGTGLGAGFGTALGAGQASLFGNNQ 453 FG + + PAP T G + FG A ++Q Sbjct: 732 FGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQ 791 Query: 454 PKIGGPLGTGAFGAP---GFNTTTATLGFGAPQAPVALTDPN 492 P GG +FGA GF TT T G+ + T P+ Sbjct: 792 PAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPS 833 Score = 44.3 bits (103), Expect = 5e-04 Identities = 91/368 (24%), Positives = 127/368 (34%), Gaps = 106/368 (28%) Query: 5 SFGTPFGGGTG-------GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQ- 56 +F PFG G FG G + T +FGSS FGNS Sbjct: 682 TFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFT----FGNSAA 737 Query: 57 ----TKPGGLFGTSSFSQPA---TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF 109 T P ++ PA T FG G ++ FG +T ++ + ++ Sbjct: 738 PAPATAPTPAPASTIKIVPAHVPTPIQPTFG-----GATHSAFGLKATASAFGAPASSQP 792 Query: 110 AQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFG---PSSFT----AAPTGTTI 162 A T +FG +TSSG FG T T++ +S S+FG PS FT AAP G+ Sbjct: 793 AFGGSTAVFSFGAATSSG--FGATTQTAS--SGSSSSVFGSTTPSPFTFGGSAAPAGS-- 846 Query: 163 KFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAG 222 N++T G+ Sbjct: 847 -------------GSFGINVATP----------------------------------GSS 859 Query: 223 TTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS--TTGFGTNPGGLFGQQNQQ 280 TTG F S G S+ T++ F G + A GT+ +T F N G + Sbjct: 860 ATTGAF------SFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGST-TESKPV 912 Query: 281 TTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTG 340 + FGQ T G S G++ + G S G GV G FG+A Sbjct: 913 FGGTATPTFGQNTPAPGVGTS-GSSLSFGASSAPAQGFVGV-------GPFGSA-----A 959 Query: 341 TAFGTGTG 348 +F G G Sbjct: 960 PSFSIGAG 967 Score = 39.7 bits (91), Expect = 0.013 Identities = 55/201 (27%), Positives = 74/201 (36%), Gaps = 29/201 (14%) Query: 10 FGGGTG-GFGTT----------STFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTK 58 FG T GFG T S FG T T GG+ + GS G+S T Sbjct: 803 FGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATT 862 Query: 59 PGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFG 118 FG ATST G G + GT T F+ + ++KP FG Sbjct: 863 GAFSFGAGQSGSTATSTPFTGGLGQNA------LGTTGQSTP-FAFNVGSTTESKPV-FG 914 Query: 119 NFGTSTSSGGLFGTTNTTSNPFGSTSGSL-FGPSSFTAAPTGTTIKFNPPTGTDTMVKAG 177 GT+T + G NT + G++ SL FG SS AP + P G Sbjct: 915 --GTATPTFG----QNTPAPGVGTSGSSLSFGASS---APAQGFVGVGPFGSAAPSFSIG 965 Query: 178 VSTNISTKHQCITAMKEYESK 198 + Q + A +++ K Sbjct: 966 AGSKTPGARQRLQARRQHTRK 986 >gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 82.4 bits (202), Expect = 2e-15 Identities = 119/498 (23%), Positives = 195/498 (39%), Gaps = 47/498 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 858 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 918 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 973 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1143 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1144 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1198 Query: 477 LGFGAPQAPVALTDPNAS 494 G A + ++ N + Sbjct: 1199 AGSETTTASTSGSETNTA 1216 Score = 78.2 bits (191), Expect = 3e-14 Identities = 117/445 (26%), Positives = 172/445 (38%), Gaps = 57/445 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 608 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 + + +A G+ TT G GT + G + + ++ G TTT +T S Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-----GSETTTTSTEGSEI 722 Query: 304 NTSTIGQPSTNTMGLFG------------VTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 T++I T T G T AS G TA+ TS+ T T + G Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET---TMASIMG 779 Query: 352 QTNTGFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 T +GS T+F N TT S+T S + +T+G P T Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPAST 837 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSK 423 G+ T T+ G+ T+ S GS+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSE 862 Score = 75.9 bits (185), Expect = 2e-13 Identities = 118/504 (23%), Positives = 189/504 (37%), Gaps = 65/504 (12%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 323 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 324 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 374 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 489 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 490 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 543 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 544 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 363 TLFGNNKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNS 418 N +T S TTSA + G TT+ ++ T T G+ T T T S + Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT----VSTTDSETT 654 Query: 419 IFGSKPAPGTLGTGLGAGFGTALGAGQASLF-----GNNQPKIGGPLGTGAFGAPGFNTT 473 + + + T+ + G+ T G + G I G T TT Sbjct: 655 MVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 474 TATLGFGAPQAPVALTDPNASAAQ 497 T+T G A + ++ ++ + Sbjct: 715 TSTEGSEITTASITGSETTTASTE 738 Score = 74.3 bits (181), Expect = 5e-13 Identities = 101/431 (23%), Positives = 167/431 (38%), Gaps = 31/431 (7%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 T ST T TT G T++ S T S+T G+ ++ S + T+ Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNT 135 T G+ T TA+T +T ++ S A+ ++ T G+ T++ G+ T Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV---KAGVSTNISTKHQCIT 190 T + GS T+ S+ G + T + TG+ TGT+T + + +T ++T T Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1044 Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250 A+ Y + S E + +G + TT GS T+S L +++ + SG Sbjct: 1045 AV--YTTGS------ETTTTSTEGSET-----TTVSTTGSETTTASTADLETTTVSTSGS 1091 Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310 TA +TT + T + S + TT TG T Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151 Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 +T + S G T T+T T TA G+ + G ++ G+ Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGS 1211 Query: 368 --NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTLTLGTN---TNTSNFGFGTNTSGNSIF 420 N T GS T++ S G T + + G++ T+ + T TS G T T + Sbjct: 1212 ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 421 GSKPAPGTLGT 431 G+ A T+ + Sbjct: 1272 GATAASTTVSS 1282 Score = 73.6 bits (179), Expect = 8e-13 Identities = 138/569 (24%), Positives = 209/569 (36%), Gaps = 78/569 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 890 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160 Query: 375 SSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLG 434 S T++ + G+ + T T G+ T T++ G+ T+ S GS+ T + G Sbjct: 1161 SEATTSSAAGSEA------TTTSTEGSETTTASTA-GSETTTASTAGSET---TTASTSG 1210 Query: 435 AGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGAPQAP 485 + TA G + + P G AF G TT TAT G+ Sbjct: 1211 SETNTACTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGSETTT 1265 Query: 486 VALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALT 545 V++T A+AA V + P+ PMS + RL A ++T Sbjct: 1266 VSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVT 1320 Query: 546 TPTHYKLTPRPATRVRPK-ALQTTGTAKS 573 T A+ P L T+G S Sbjct: 1321 MAPGMDFTASAASHTVPGIVLNTSGLGTS 1349 Score = 68.6 bits (166), Expect = 3e-11 Identities = 94/400 (23%), Positives = 149/400 (37%), Gaps = 54/400 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S G T + SG T++ S NT S T + G+ + A S +T Sbjct: 47 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 + T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 ++ GS ++F S T P+ TT+ T +T ST H TA Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 S++ + + G+ TT GS +S S TN+ F Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268 Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311 T STTGF T G + +++ G TT STIG Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGPE 312 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T +S+ +F + T + G+ T + TG +++ G+ T Sbjct: 313 TTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETST 365 Query: 372 --TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405 Score = 68.2 bits (165), Expect = 3e-11 Identities = 126/505 (24%), Positives = 188/505 (37%), Gaps = 59/505 (11%) Query: 18 GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77 G+ T TG TT+ G+ +S L S T T + S + T+T Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965 Query: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136 G+ T TA+T +T ++ S A + ++ T + G+ T++ GT T Sbjct: 966 VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025 Query: 137 SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 ++ GS + ++ T A + TT + TG++T ST S T E Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246 + S +L + G AG TT + GS T+S G SS TT Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134 Query: 247 NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306 + + T F TT T G ++ TTS S +ATTT G S Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187 Query: 307 TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTL 364 T G +T +T G T AS G TA T + T+ + G +TNT F T Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAFIIGSETT 1244 Query: 365 FGN--------NKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSG 416 + LT ++T S + G T+ + T L T+ S TNT Sbjct: 1245 IASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI-TNT-- 1301 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 + G++ T GT L A + G AS + P G L T G + Sbjct: 1302 -PMSGTR----TTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGAS 1354 Query: 474 TATLGFGAPQAPVALTDPNASAAQQ 498 + T G + +P +S Q+ Sbjct: 1355 STTSAHGVRTTTGSTREPTSSTFQE 1379 Score = 66.2 bits (160), Expect = 1e-10 Identities = 106/441 (24%), Positives = 173/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 621 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT+ + G+ T+ + G++ T T G+ Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 742 TTTASTE-GSETTSASTTGSE 761 Score = 59.3 bits (142), Expect = 2e-08 Identities = 90/380 (23%), Positives = 152/380 (40%), Gaps = 53/380 (13%) Query: 71 PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122 PA ++T T + T L + T T+ S+ + PTG G+ T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +TS+ G TT +++ G+T+ S+ G S T + G+ TGT+T + + + + Sbjct: 67 TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242 +T S + E + + + VG+ TTT S T+++T Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173 Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 +T + + + G+ TT T +TT++ + G TTT +T S Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223 Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359 ST+G +T T S G A+ ++ T TAF + + TGF Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283 Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL------------TLGTNT 403 ++ G+ +T GS TT A + G TT ++ T T+G+ T Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343 Query: 404 NTSNFGFGTNTSGNSIFGSK 423 T + G+ T+ SI GS+ Sbjct: 344 TTVS-TTGSETTTASIMGSE 362 Score = 43.1 bits (100), Expect = 0.001 Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 71/331 (21%) Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188 G+ TT++ GS + ++ +S TA+ G+ PTG+ T + + + I+T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69 Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E + S G+GTTT S T S G S +TT Sbjct: 70 -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106 Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308 S TG T G + T+ S + T T G ST+ Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150 Query: 309 GQPSTNTMGLFGVTQASQPGG-----LFGTATNTSTGTAFGTGT---GLFGQTNTGFGAV 360 G +T T A+ G +F + T T + G+ T G T Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT 210 Query: 361 GSTLFG-------NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF--- 410 GS +T GS TT + G+ + T T + +N F Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTED 270 Query: 411 ---------GTNTSGNSIFGSKPA-PGTLGT 431 G T+ S GS+P T+G+ Sbjct: 271 SKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Score = 40.4 bits (93), Expect = 0.008 Identities = 67/267 (25%), Positives = 96/267 (35%), Gaps = 50/267 (18%) Query: 229 GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP 288 GS+ T+S TG S TT + TA ST G T G Q T++ S Sbjct: 12 GSNTTTASTTG---SETTTILIKASETTTA---STAGSETTTPSPTGSQ----TTIVSIS 61 Query: 289 FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348 + TTT G S+ G G T AS + G+ T ST + T Sbjct: 62 GSEITTTSTAGSENTTVSSAGS---------GTTTAS----MAGSETTVSTAGSETTTVS 108 Query: 349 LFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408 + G T A+GS T +STTS+ + T++ G T S Sbjct: 109 ITGTETTMVSAMGSE--------TTTNSTTSSETTVTSTAG----------SETTTVSTV 150 Query: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468 G T T+ + + T + G+ T AG ++ P G T A Sbjct: 151 GSETTTAYTA-----DSETTAASTTGSEMTTVFTAGSETI----TPSTAGSETTTVSTAG 201 Query: 469 GFNTTTATLGFGAPQAPVALTDPNASA 495 TT +T G A A ++ A++ Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAAS 228 Score = 30.8 bits (68), Expect = 6.2 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 ++ T P+ + T S+ + A+ T+T + G+ T T + V + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 364 LFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFGFGTNTSGNSIF 420 +T GS +T S+ GTT+ + G++ T+ T G+ T T + GT T+ S Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI-TGTETTMVSAM 120 Query: 421 GSK 423 GS+ Sbjct: 121 GSE 123 >gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 82.4 bits (202), Expect = 2e-15 Identities = 119/498 (23%), Positives = 195/498 (39%), Gaps = 47/498 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 858 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 918 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 973 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1143 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1144 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1198 Query: 477 LGFGAPQAPVALTDPNAS 494 G A + ++ N + Sbjct: 1199 AGSETTTASTSGSETNTA 1216 Score = 78.2 bits (191), Expect = 3e-14 Identities = 117/445 (26%), Positives = 172/445 (38%), Gaps = 57/445 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 608 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 + + +A G+ TT G GT + G + + ++ G TTT +T S Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-----GSETTTTSTEGSEI 722 Query: 304 NTSTIGQPSTNTMGLFG------------VTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 T++I T T G T AS G TA+ TS+ T T + G Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET---TMASIMG 779 Query: 352 QTNTGFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 T +GS T+F N TT S+T S + +T+G P T Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPAST 837 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSK 423 G+ T T+ G+ T+ S GS+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSE 862 Score = 75.9 bits (185), Expect = 2e-13 Identities = 118/504 (23%), Positives = 189/504 (37%), Gaps = 65/504 (12%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 323 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 324 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 374 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 489 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 490 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 543 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 544 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 363 TLFGNNKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNS 418 N +T S TTSA + G TT+ ++ T T G+ T T T S + Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT----VSTTDSETT 654 Query: 419 IFGSKPAPGTLGTGLGAGFGTALGAGQASLF-----GNNQPKIGGPLGTGAFGAPGFNTT 473 + + + T+ + G+ T G + G I G T TT Sbjct: 655 MVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 474 TATLGFGAPQAPVALTDPNASAAQ 497 T+T G A + ++ ++ + Sbjct: 715 TSTEGSEITTASITGSETTTASTE 738 Score = 74.3 bits (181), Expect = 5e-13 Identities = 101/431 (23%), Positives = 167/431 (38%), Gaps = 31/431 (7%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 T ST T TT G T++ S T S+T G+ ++ S + T+ Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNT 135 T G+ T TA+T +T ++ S A+ ++ T G+ T++ G+ T Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV---KAGVSTNISTKHQCIT 190 T + GS T+ S+ G + T + TG+ TGT+T + + +T ++T T Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1044 Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250 A+ Y + S E + +G + TT GS T+S L +++ + SG Sbjct: 1045 AV--YTTGS------ETTTTSTEGSET-----TTVSTTGSETTTASTADLETTTVSTSGS 1091 Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310 TA +TT + T + S + TT TG T Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151 Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 +T + S G T T+T T TA G+ + G ++ G+ Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGS 1211 Query: 368 --NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTLTLGTN---TNTSNFGFGTNTSGNSIF 420 N T GS T++ S G T + + G++ T+ + T TS G T T + Sbjct: 1212 ETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 421 GSKPAPGTLGT 431 G+ A T+ + Sbjct: 1272 GATAASTTVSS 1282 Score = 72.8 bits (177), Expect = 1e-12 Identities = 136/568 (23%), Positives = 208/568 (36%), Gaps = 76/568 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 890 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160 Query: 375 SSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLG 434 S T++ + G+ + T T G+ T T++ G+ T+ S GS+ T + G Sbjct: 1161 SEATTSSAAGSEA------TTTSTEGSETTTASTA-GSETTTASTAGSET---TTASTSG 1210 Query: 435 AGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNT--------TTATLGFGAPQAPV 486 + TA G + + P G AF +T TAT G+ V Sbjct: 1211 SETNTACTTGSET----STPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTV 1266 Query: 487 ALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTT 546 ++T A+AA V + P+ PMS + RL A ++T Sbjct: 1267 SITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTM 1321 Query: 547 PTHYKLTPRPATRVRPK-ALQTTGTAKS 573 T A+ P L T+G S Sbjct: 1322 APGMDFTASAASHTVPGIVLNTSGLGTS 1349 Score = 68.6 bits (166), Expect = 3e-11 Identities = 94/400 (23%), Positives = 149/400 (37%), Gaps = 54/400 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S G T + SG T++ S NT S T + G+ + A S +T Sbjct: 47 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 + T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 ++ GS ++F S T P+ TT+ T +T ST H TA Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 S++ + + G+ TT GS +S S TN+ F Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268 Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311 T STTGF T G + +++ G TT STIG Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGPE 312 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T +S+ +F + T + G+ T + TG +++ G+ T Sbjct: 313 TTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETST 365 Query: 372 --TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405 Score = 67.4 bits (163), Expect = 6e-11 Identities = 129/505 (25%), Positives = 190/505 (37%), Gaps = 59/505 (11%) Query: 18 GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77 G+ T TG TT+ G+ +S L S T T + S + T+T Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965 Query: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136 G+ T TA+T +T ++ S A + ++ T + G+ T++ GT T Sbjct: 966 VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025 Query: 137 SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 ++ GS + ++ T A + TT + TG++T ST S T E Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246 + S +L + G AG TT + GS T+S G SS TT Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134 Query: 247 NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306 + + T F TT T G ++ TTS S +ATTT G S Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187 Query: 307 TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF-----GA 359 T G +T +T G T AS G TA T + T+ + G +TNT F Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAFIIGSEST 1244 Query: 360 VGSTLFGNNKLTTF-GSSTT--SAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSG 416 + ST T+ GS TT S + G T+ + T L T+ S TNT Sbjct: 1245 IASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI-TNT-- 1301 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 + G++ T GT L A + G AS + P G L T G + Sbjct: 1302 -PMSGTR----TTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGAS 1354 Query: 474 TATLGFGAPQAPVALTDPNASAAQQ 498 + T G + +P +S Q+ Sbjct: 1355 STTSAHGVRTTTGSTREPTSSTFQE 1379 Score = 66.2 bits (160), Expect = 1e-10 Identities = 106/441 (24%), Positives = 173/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 621 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT+ + G+ T+ + G++ T T G+ Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 742 TTTASTE-GSETTSASTTGSE 761 Score = 59.3 bits (142), Expect = 2e-08 Identities = 90/380 (23%), Positives = 152/380 (40%), Gaps = 53/380 (13%) Query: 71 PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122 PA ++T T + T L + T T+ S+ + PTG G+ T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +TS+ G TT +++ G+T+ S+ G S T + G+ TGT+T + + + + Sbjct: 67 TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242 +T S + E + + + VG+ TTT S T+++T Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173 Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 +T + + + G+ TT T +TT++ + G TTT +T S Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223 Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359 ST+G +T T S G A+ ++ T TAF + + TGF Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283 Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL------------TLGTNT 403 ++ G+ +T GS TT A + G TT ++ T T+G+ T Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343 Query: 404 NTSNFGFGTNTSGNSIFGSK 423 T + G+ T+ SI GS+ Sbjct: 344 TTVS-TTGSETTTASIMGSE 362 Score = 43.1 bits (100), Expect = 0.001 Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 71/331 (21%) Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188 G+ TT++ GS + ++ +S TA+ G+ PTG+ T + + + I+T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69 Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E + S G+GTTT S T S G S +TT Sbjct: 70 -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106 Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308 S TG T G + T+ S + T T G ST+ Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150 Query: 309 GQPSTNTMGLFGVTQASQPGG-----LFGTATNTSTGTAFGTGT---GLFGQTNTGFGAV 360 G +T T A+ G +F + T T + G+ T G T Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT 210 Query: 361 GSTLFG-------NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF--- 410 GS +T GS TT + G+ + T T + +N F Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTED 270 Query: 411 ---------GTNTSGNSIFGSKPA-PGTLGT 431 G T+ S GS+P T+G+ Sbjct: 271 SKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Score = 40.4 bits (93), Expect = 0.008 Identities = 67/267 (25%), Positives = 96/267 (35%), Gaps = 50/267 (18%) Query: 229 GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP 288 GS+ T+S TG S TT + TA ST G T G Q T++ S Sbjct: 12 GSNTTTASTTG---SETTTILIKASETTTA---STAGSETTTPSPTGSQ----TTIVSIS 61 Query: 289 FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348 + TTT G S+ G G T AS + G+ T ST + T Sbjct: 62 GSEITTTSTAGSENTTVSSAGS---------GTTTAS----MAGSETTVSTAGSETTTVS 108 Query: 349 LFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408 + G T A+GS T +STTS+ + T++ G T S Sbjct: 109 ITGTETTMVSAMGSE--------TTTNSTTSSETTVTSTAG----------SETTTVSTV 150 Query: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468 G T T+ + + T + G+ T AG ++ P G T A Sbjct: 151 GSETTTAYTA-----DSETTAASTTGSEMTTVFTAGSETI----TPSTAGSETTTVSTAG 201 Query: 469 GFNTTTATLGFGAPQAPVALTDPNASA 495 TT +T G A A ++ A++ Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAAS 228 Score = 30.8 bits (68), Expect = 6.2 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 ++ T P+ + T S+ + A+ T+T + G+ T T + V + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 364 LFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFGFGTNTSGNSIF 420 +T GS +T S+ GTT+ + G++ T+ T G+ T T + GT T+ S Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI-TGTETTMVSAM 120 Query: 421 GSK 423 GS+ Sbjct: 121 GSE 123 >gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] Length = 1542 Score = 82.4 bits (202), Expect = 2e-15 Identities = 119/498 (23%), Positives = 195/498 (39%), Gaps = 47/498 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 765 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 819 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 820 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 878 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 879 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 938 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 939 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 993 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 994 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1049 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1050 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1104 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1105 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1164 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1165 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1219 Query: 477 LGFGAPQAPVALTDPNAS 494 G A + ++ N + Sbjct: 1220 AGSETTTASTSGSETNTA 1237 Score = 78.2 bits (191), Expect = 3e-14 Identities = 117/445 (26%), Positives = 172/445 (38%), Gaps = 57/445 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 456 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 515 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 516 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 569 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 570 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 628 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 629 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 688 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 + + +A G+ TT G GT + G + + ++ G TTT +T S Sbjct: 689 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-----GSETTTTSTEGSEI 743 Query: 304 NTSTIGQPSTNTMGLFG------------VTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 T++I T T G T AS G TA+ TS+ T T + G Sbjct: 744 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET---TMASIMG 800 Query: 352 QTNTGFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 T +GS T+F N TT S+T S + +T+G P T Sbjct: 801 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPAST 858 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSK 423 G+ T T+ G+ T+ S GS+ Sbjct: 859 AGSETTTTTSTEGSETTTASTEGSE 883 Score = 75.9 bits (185), Expect = 2e-13 Identities = 118/504 (23%), Positives = 189/504 (37%), Gaps = 65/504 (12%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 294 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 344 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 345 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 395 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 396 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 455 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 456 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 510 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 511 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 564 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 565 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 619 Query: 363 TLFGNNKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNS 418 N +T S TTSA + G TT+ ++ T T G+ T T T S + Sbjct: 620 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT----VSTTDSETT 675 Query: 419 IFGSKPAPGTLGTGLGAGFGTALGAGQASLF-----GNNQPKIGGPLGTGAFGAPGFNTT 473 + + + T+ + G+ T G + G I G T TT Sbjct: 676 MVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 735 Query: 474 TATLGFGAPQAPVALTDPNASAAQ 497 T+T G A + ++ ++ + Sbjct: 736 TSTEGSEITTASITGSETTTASTE 759 Score = 74.3 bits (181), Expect = 5e-13 Identities = 101/431 (23%), Positives = 167/431 (38%), Gaps = 31/431 (7%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 T ST T TT G T++ S T S+T G+ ++ S + T+ Sbjct: 886 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 945 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNT 135 T G+ T TA+T +T ++ S A+ ++ T G+ T++ G+ T Sbjct: 946 TASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 1005 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV---KAGVSTNISTKHQCIT 190 T + GS T+ S+ G + T + TG+ TGT+T + + +T ++T T Sbjct: 1006 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1065 Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250 A+ Y + S E + +G + TT GS T+S L +++ + SG Sbjct: 1066 AV--YTTGS------ETTTTSTEGSET-----TTVSTTGSETTTASTADLETTTVSTSGS 1112 Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310 TA +TT + T + S + TT TG T Sbjct: 1113 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1172 Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 +T + S G T T+T T TA G+ + G ++ G+ Sbjct: 1173 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGS 1232 Query: 368 --NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTLTLGTN---TNTSNFGFGTNTSGNSIF 420 N T GS T++ S G T + + G++ T+ + T TS G T T + Sbjct: 1233 ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1292 Query: 421 GSKPAPGTLGT 431 G+ A T+ + Sbjct: 1293 GATAASTTVSS 1303 Score = 73.6 bits (179), Expect = 8e-13 Identities = 138/569 (24%), Positives = 209/569 (36%), Gaps = 78/569 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 866 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 910 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 911 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 958 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 959 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 1015 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 1016 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1074 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1075 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1127 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1128 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1181 Query: 375 SSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLG 434 S T++ + G+ + T T G+ T T++ G+ T+ S GS+ T + G Sbjct: 1182 SEATTSSAAGSEA------TTTSTEGSETTTASTA-GSETTTASTAGSET---TTASTSG 1231 Query: 435 AGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGAPQAP 485 + TA G + + P G AF G TT TAT G+ Sbjct: 1232 SETNTACTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGSETTT 1286 Query: 486 VALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALT 545 V++T A+AA V + P+ PMS + RL A ++T Sbjct: 1287 VSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVT 1341 Query: 546 TPTHYKLTPRPATRVRPK-ALQTTGTAKS 573 T A+ P L T+G S Sbjct: 1342 MAPGMDFTASAASHTVPGIVLNTSGLGTS 1370 Score = 68.9 bits (167), Expect = 2e-11 Identities = 99/401 (24%), Positives = 151/401 (37%), Gaps = 56/401 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGT-SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77 T S G T + SG T S GS N T G+ T S+ S + T+T Sbjct: 68 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTT 127 Query: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQN--NAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 GT T T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 128 VSITGTET-TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT 186 Query: 136 TSNPFGSTSGSLFGPSSFTAAPT-----GTTIKFNPPTGTDTMVKAGVSTNISTKHQCIT 190 ++ GS ++F S T P+ TT+ T +T ST H T Sbjct: 187 AASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETT 246 Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250 A S++ + + G+ TT GS +S S TN+ F Sbjct: 247 AASTMGSETTK--------------VSTAGSETTVSTAGSETTAAST----EDSETNTAF 288 Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310 T STTGF T G + +++ G TT STIG Sbjct: 289 TEDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGP 332 Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKL 370 +T T +S+ +F + T + G+ T + TG +++ G+ Sbjct: 333 ETTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETS 385 Query: 371 T--TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 386 TDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 426 Score = 68.2 bits (165), Expect = 3e-11 Identities = 126/505 (24%), Positives = 188/505 (37%), Gaps = 59/505 (11%) Query: 18 GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77 G+ T TG TT+ G+ +S L S T T + S + T+T Sbjct: 931 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 986 Query: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136 G+ T TA+T +T ++ S A + ++ T + G+ T++ GT T Sbjct: 987 VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1046 Query: 137 SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 ++ GS + ++ T A + TT + TG++T ST S T E Sbjct: 1047 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1095 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246 + S +L + G AG TT + GS T+S G SS TT Sbjct: 1096 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1155 Query: 247 NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306 + + T F TT T G ++ TTS S +ATTT G S Sbjct: 1156 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1208 Query: 307 TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTL 364 T G +T +T G T AS G TA T + T+ + G +TNT F T Sbjct: 1209 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAFIIGSETT 1265 Query: 365 FGN--------NKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSG 416 + LT ++T S + G T+ + T L T+ S TNT Sbjct: 1266 IASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI-TNT-- 1322 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 + G++ T GT L A + G AS + P G L T G + Sbjct: 1323 -PMSGTR----TTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGAS 1375 Query: 474 TATLGFGAPQAPVALTDPNASAAQQ 498 + T G + +P +S Q+ Sbjct: 1376 STTSAHGVRTTTGSTREPTSSTFQE 1400 Score = 66.2 bits (160), Expect = 1e-10 Identities = 106/441 (24%), Positives = 173/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 361 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 415 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 416 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 475 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 476 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 529 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 530 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 584 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 585 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 642 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 643 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 702 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT+ + G+ T+ + G++ T T G+ Sbjct: 703 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 762 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 763 TTTASTE-GSETTSASTTGSE 782 Score = 52.0 bits (123), Expect = 3e-06 Identities = 95/408 (23%), Positives = 149/408 (36%), Gaps = 48/408 (11%) Query: 83 TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGS 142 T+T TA++ TAS+ SS+ P N T++++G TT + Sbjct: 7 TTTSTADSKVITASS----MSSETTV----APAAGSNTTTASTTGS--ETTTILIKASET 56 Query: 143 TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKS 199 T+ S G + T +PTG T + + T T +T +S+ T S+S Sbjct: 57 TTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSES 116 Query: 200 L-----EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254 E + +G+ TTT SS T ++T S TT + Sbjct: 117 TISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTA--GSETTTVSTVGSE 174 Query: 255 NKTAF--GTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNT-STIGQP 311 TA+ + TT T + + ++ G TTT +T S T ST G Sbjct: 175 TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSE 234 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T A+ G T +T+ + G + + +T F + T Sbjct: 235 TTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKT 294 Query: 372 TFGSSTTSAPSFGTTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTL 429 T T S F TT+ G++PT+ T+G+ T + +T G A + Sbjct: 295 T----TASTTGFETTAASTTGSEPTMASTMGSETTMA------STIGPETTKVSTASSEV 344 Query: 430 GTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATL 477 T AG T +AS G+ T G TTTA++ Sbjct: 345 TTVFAAGSETI----RASTVGSE---------TTTVSTTGSETTTASI 379 Score = 33.5 bits (75), Expect = 0.95 Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 11/142 (7%) Query: 291 QATTTQN------TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344 +ATTT T S + +T+ P+ + T S+ + A+ T+T + G Sbjct: 5 EATTTSTADSKVITASSMSSETTVA-PAAGSNTTTASTTGSETTTILIKASETTTASTAG 63 Query: 345 TGTGLFGQTNTGFGAVGSTLFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGT 401 + T T + V + +T GS +T S+ GTT+ + G++ T+ T G+ Sbjct: 64 SETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGS 123 Query: 402 NTNTSNFGFGTNTSGNSIFGSK 423 T T + GT T+ S GS+ Sbjct: 124 ETTTVSI-TGTETTMVSAMGSE 144 >gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo sapiens] Length = 1521 Score = 82.4 bits (202), Expect = 2e-15 Identities = 119/498 (23%), Positives = 195/498 (39%), Gaps = 47/498 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 858 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 918 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 973 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1143 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1144 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1198 Query: 477 LGFGAPQAPVALTDPNAS 494 G A + ++ N + Sbjct: 1199 AGSETTTASTSGSETNTA 1216 Score = 79.3 bits (194), Expect = 2e-14 Identities = 118/441 (26%), Positives = 172/441 (39%), Gaps = 49/441 (11%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 608 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQT------TSLFSKPFGQATTTQN 297 + + +A G+ TT G GT + G + + T++ S + TT Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASI 727 Query: 298 TGFSFGNTSTIGQPSTNTMGLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNT 355 TG ST G +T T G T AS G TA+ TS+ T T + G T Sbjct: 728 TGSETTTASTEGSETT-TASTEGSETTSASTTGSETTTASTTSSET---TMASIMGSETT 783 Query: 356 GFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTN 402 +GS T+F N TT S+T S + +T+G P T G+ Sbjct: 784 MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPASTAGSE 841 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T+ G+ T+ S GS+ Sbjct: 842 TTTTTSTEGSETTTASTEGSE 862 Score = 75.5 bits (184), Expect = 2e-13 Identities = 109/453 (24%), Positives = 171/453 (37%), Gaps = 75/453 (16%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 323 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 324 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 374 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 489 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 490 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 543 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 544 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 363 TLFGNNKLTTFGSSTTSAPSFG------------TTSGGLFGNKPTLTLGTNTNTSNFGF 410 N +T S TTSA + G TT+ G++ T T++ T+ Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658 Query: 411 -----------GTNTSGNSIFGSKPAPGTLGTG 432 G+ T+ S GS+ T G+G Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEGSG 691 Score = 74.3 bits (181), Expect = 5e-13 Identities = 101/431 (23%), Positives = 167/431 (38%), Gaps = 31/431 (7%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 T ST T TT G T++ S T S+T G+ ++ S + T+ Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNT 135 T G+ T TA+T +T ++ S A+ ++ T G+ T++ G+ T Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV---KAGVSTNISTKHQCIT 190 T + GS T+ S+ G + T + TG+ TGT+T + + +T ++T T Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1044 Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250 A+ Y + S E + +G + TT GS T+S L +++ + SG Sbjct: 1045 AV--YTTGS------ETTTTSTEGSET-----TTVSTTGSETTTASTADLETTTVSTSGS 1091 Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310 TA +TT + T + S + TT TG T Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151 Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 +T + S G T T+T T TA G+ + G ++ G+ Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGS 1211 Query: 368 --NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTLTLGTN---TNTSNFGFGTNTSGNSIF 420 N T GS T++ S G T + + G++ T+ + T TS G T T + Sbjct: 1212 ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 421 GSKPAPGTLGT 431 G+ A T+ + Sbjct: 1272 GATAASTTVSS 1282 Score = 73.6 bits (179), Expect = 8e-13 Identities = 138/569 (24%), Positives = 209/569 (36%), Gaps = 78/569 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 890 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160 Query: 375 SSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLG 434 S T++ + G+ + T T G+ T T++ G+ T+ S GS+ T + G Sbjct: 1161 SEATTSSAAGSEA------TTTSTEGSETTTASTA-GSETTTASTAGSET---TTASTSG 1210 Query: 435 AGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGAPQAP 485 + TA G + + P G AF G TT TAT G+ Sbjct: 1211 SETNTACTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGSETTT 1265 Query: 486 VALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALT 545 V++T A+AA V + P+ PMS + RL A ++T Sbjct: 1266 VSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVT 1320 Query: 546 TPTHYKLTPRPATRVRPK-ALQTTGTAKS 573 T A+ P L T+G S Sbjct: 1321 MAPGMDFTASAASHTVPGIVLNTSGLGTS 1349 Score = 68.6 bits (166), Expect = 3e-11 Identities = 94/400 (23%), Positives = 149/400 (37%), Gaps = 54/400 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S G T + SG T++ S NT S T + G+ + A S +T Sbjct: 47 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 + T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 ++ GS ++F S T P+ TT+ T +T ST H TA Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 S++ + + G+ TT GS +S S TN+ F Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268 Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311 T STTGF T G + +++ G TT STIG Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGPE 312 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T +S+ +F + T + G+ T + TG +++ G+ T Sbjct: 313 TTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETST 365 Query: 372 --TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405 Score = 68.2 bits (165), Expect = 3e-11 Identities = 126/505 (24%), Positives = 188/505 (37%), Gaps = 59/505 (11%) Query: 18 GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77 G+ T TG TT+ G+ +S L S T T + S + T+T Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965 Query: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136 G+ T TA+T +T ++ S A + ++ T + G+ T++ GT T Sbjct: 966 VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025 Query: 137 SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 ++ GS + ++ T A + TT + TG++T ST S T E Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246 + S +L + G AG TT + GS T+S G SS TT Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134 Query: 247 NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306 + + T F TT T G ++ TTS S +ATTT G S Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187 Query: 307 TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTL 364 T G +T +T G T AS G TA T + T+ + G +TNT F T Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAFIIGSETT 1244 Query: 365 FGN--------NKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSG 416 + LT ++T S + G T+ + T L T+ S TNT Sbjct: 1245 IASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI-TNT-- 1301 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 + G++ T GT L A + G AS + P G L T G + Sbjct: 1302 -PMSGTR----TTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGAS 1354 Query: 474 TATLGFGAPQAPVALTDPNASAAQQ 498 + T G + +P +S Q+ Sbjct: 1355 STTSAHGVRTTTGSTREPTSSTFQE 1379 Score = 65.1 bits (157), Expect = 3e-10 Identities = 106/441 (24%), Positives = 172/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 621 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT + G+ T+ + G++ T T G+ Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSE 741 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 742 TTTASTE-GSETTSASTTGSE 761 Score = 59.3 bits (142), Expect = 2e-08 Identities = 90/380 (23%), Positives = 152/380 (40%), Gaps = 53/380 (13%) Query: 71 PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122 PA ++T T + T L + T T+ S+ + PTG G+ T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +TS+ G TT +++ G+T+ S+ G S T + G+ TGT+T + + + + Sbjct: 67 TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242 +T S + E + + + VG+ TTT S T+++T Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173 Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 +T + + + G+ TT T +TT++ + G TTT +T S Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223 Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359 ST+G +T T S G A+ ++ T TAF + + TGF Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283 Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL------------TLGTNT 403 ++ G+ +T GS TT A + G TT ++ T T+G+ T Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343 Query: 404 NTSNFGFGTNTSGNSIFGSK 423 T + G+ T+ SI GS+ Sbjct: 344 TTVS-TTGSETTTASIMGSE 362 Score = 43.1 bits (100), Expect = 0.001 Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 71/331 (21%) Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188 G+ TT++ GS + ++ +S TA+ G+ PTG+ T + + + I+T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69 Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E + S G+GTTT S T S G S +TT Sbjct: 70 -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106 Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308 S TG T G + T+ S + T T G ST+ Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150 Query: 309 GQPSTNTMGLFGVTQASQPGG-----LFGTATNTSTGTAFGTGT---GLFGQTNTGFGAV 360 G +T T A+ G +F + T T + G+ T G T Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT 210 Query: 361 GSTLFG-------NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF--- 410 GS +T GS TT + G+ + T T + +N F Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTED 270 Query: 411 ---------GTNTSGNSIFGSKPA-PGTLGT 431 G T+ S GS+P T+G+ Sbjct: 271 SKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Score = 40.4 bits (93), Expect = 0.008 Identities = 67/267 (25%), Positives = 96/267 (35%), Gaps = 50/267 (18%) Query: 229 GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP 288 GS+ T+S TG S TT + TA ST G T G Q T++ S Sbjct: 12 GSNTTTASTTG---SETTTILIKASETTTA---STAGSETTTPSPTGSQ----TTIVSIS 61 Query: 289 FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348 + TTT G S+ G G T AS + G+ T ST + T Sbjct: 62 GSEITTTSTAGSENTTVSSAGS---------GTTTAS----MAGSETTVSTAGSETTTVS 108 Query: 349 LFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408 + G T A+GS T +STTS+ + T++ G T S Sbjct: 109 ITGTETTMVSAMGSE--------TTTNSTTSSETTVTSTAG----------SETTTVSTV 150 Query: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468 G T T+ + + T + G+ T AG ++ P G T A Sbjct: 151 GSETTTAYTA-----DSETTAASTTGSEMTTVFTAGSETI----TPSTAGSETTTVSTAG 201 Query: 469 GFNTTTATLGFGAPQAPVALTDPNASA 495 TT +T G A A ++ A++ Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAAS 228 Score = 30.8 bits (68), Expect = 6.2 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 ++ T P+ + T S+ + A+ T+T + G+ T T + V + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 364 LFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFGFGTNTSGNSIF 420 +T GS +T S+ GTT+ + G++ T+ T G+ T T + GT T+ S Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI-TGTETTMVSAM 120 Query: 421 GSK 423 GS+ Sbjct: 121 GSE 123 >gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 82.4 bits (202), Expect = 2e-15 Identities = 119/498 (23%), Positives = 195/498 (39%), Gaps = 47/498 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 858 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 918 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 973 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1143 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1144 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1198 Query: 477 LGFGAPQAPVALTDPNAS 494 G A + ++ N + Sbjct: 1199 AGSETTTASTSGSETNTA 1216 Score = 78.2 bits (191), Expect = 3e-14 Identities = 117/445 (26%), Positives = 172/445 (38%), Gaps = 57/445 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 608 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 + + +A G+ TT G GT + G + + ++ G TTT +T S Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-----GSETTTTSTEGSEI 722 Query: 304 NTSTIGQPSTNTMGLFG------------VTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 T++I T T G T AS G TA+ TS+ T T + G Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET---TMASIMG 779 Query: 352 QTNTGFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 T +GS T+F N TT S+T S + +T+G P T Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPAST 837 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSK 423 G+ T T+ G+ T+ S GS+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSE 862 Score = 76.3 bits (186), Expect = 1e-13 Identities = 139/569 (24%), Positives = 209/569 (36%), Gaps = 78/569 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 890 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160 Query: 375 SSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLG 434 S T++ + G+ + T T G+ T T++ G+ T+ S GS+ T + G Sbjct: 1161 SEATTSSAAGSEA------TTTSTEGSETTTASTA-GSETTTASTAGSET---TTASTSG 1210 Query: 435 AGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGAPQAP 485 + TA G + + P G AF G TT TAT G+ Sbjct: 1211 SETNTACTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGSETTT 1265 Query: 486 VALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALT 545 V++T A+AA V + P+ PMS R T P A ++T Sbjct: 1266 VSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSG-----TRTTGTRPTASSSVT 1320 Query: 546 TPTHYKLTPRPATRVRPK-ALQTTGTAKS 573 T A+ P L T+G S Sbjct: 1321 MAPGMDFTASAASHTVPGIVLNTSGLGTS 1349 Score = 75.9 bits (185), Expect = 2e-13 Identities = 118/504 (23%), Positives = 189/504 (37%), Gaps = 65/504 (12%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 323 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 324 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 374 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 489 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 490 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 543 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 544 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 363 TLFGNNKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNS 418 N +T S TTSA + G TT+ ++ T T G+ T T T S + Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT----VSTTDSETT 654 Query: 419 IFGSKPAPGTLGTGLGAGFGTALGAGQASLF-----GNNQPKIGGPLGTGAFGAPGFNTT 473 + + + T+ + G+ T G + G I G T TT Sbjct: 655 MVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 474 TATLGFGAPQAPVALTDPNASAAQ 497 T+T G A + ++ ++ + Sbjct: 715 TSTEGSEITTASITGSETTTASTE 738 Score = 68.6 bits (166), Expect = 3e-11 Identities = 94/400 (23%), Positives = 149/400 (37%), Gaps = 54/400 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S G T + SG T++ S NT S T + G+ + A S +T Sbjct: 47 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 + T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 ++ GS ++F S T P+ TT+ T +T ST H TA Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 S++ + + G+ TT GS +S S TN+ F Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268 Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311 T STTGF T G + +++ G TT STIG Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGPE 312 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T +S+ +F + T + G+ T + TG +++ G+ T Sbjct: 313 TTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETST 365 Query: 372 --TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405 Score = 67.8 bits (164), Expect = 5e-11 Identities = 126/505 (24%), Positives = 188/505 (37%), Gaps = 59/505 (11%) Query: 18 GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77 G+ T TG TT+ G+ +S L S T T + S + T+T Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965 Query: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136 G+ T TA+T +T ++ S A + ++ T + G+ T++ GT T Sbjct: 966 VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025 Query: 137 SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 ++ GS + ++ T A + TT + TG++T ST S T E Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246 + S +L + G AG TT + GS T+S G SS TT Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134 Query: 247 NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306 + + T F TT T G ++ TTS S +ATTT G S Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187 Query: 307 TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTL 364 T G +T +T G T AS G TA T + T+ + G +TNT F T Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAFIIGSETT 1244 Query: 365 FGN--------NKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNT-- 414 + LT ++T S + G T+ + T L T+ S TNT Sbjct: 1245 IASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI-TNTPM 1303 Query: 415 SGNSIFGSKP-APGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 SG G++P A ++ G F AS + P G L T G + Sbjct: 1304 SGTRTTGTRPTASSSVTMAPGMDF-------TASAASHTVP--GIVLNTSGLGTSTMGAS 1354 Query: 474 TATLGFGAPQAPVALTDPNASAAQQ 498 + T G + +P +S Q+ Sbjct: 1355 STTSAHGVRTTTGSTREPTSSTFQE 1379 Score = 66.2 bits (160), Expect = 1e-10 Identities = 106/441 (24%), Positives = 173/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 621 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT+ + G+ T+ + G++ T T G+ Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 742 TTTASTE-GSETTSASTTGSE 761 Score = 59.3 bits (142), Expect = 2e-08 Identities = 90/380 (23%), Positives = 152/380 (40%), Gaps = 53/380 (13%) Query: 71 PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122 PA ++T T + T L + T T+ S+ + PTG G+ T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +TS+ G TT +++ G+T+ S+ G S T + G+ TGT+T + + + + Sbjct: 67 TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242 +T S + E + + + VG+ TTT S T+++T Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173 Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 +T + + + G+ TT T +TT++ + G TTT +T S Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223 Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359 ST+G +T T S G A+ ++ T TAF + + TGF Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283 Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL------------TLGTNT 403 ++ G+ +T GS TT A + G TT ++ T T+G+ T Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343 Query: 404 NTSNFGFGTNTSGNSIFGSK 423 T + G+ T+ SI GS+ Sbjct: 344 TTVS-TTGSETTTASIMGSE 362 Score = 43.1 bits (100), Expect = 0.001 Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 71/331 (21%) Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188 G+ TT++ GS + ++ +S TA+ G+ PTG+ T + + + I+T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69 Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E + S G+GTTT S T S G S +TT Sbjct: 70 -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106 Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308 S TG T G + T+ S + T T G ST+ Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150 Query: 309 GQPSTNTMGLFGVTQASQPGG-----LFGTATNTSTGTAFGTGT---GLFGQTNTGFGAV 360 G +T T A+ G +F + T T + G+ T G T Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT 210 Query: 361 GSTLFG-------NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF--- 410 GS +T GS TT + G+ + T T + +N F Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTED 270 Query: 411 ---------GTNTSGNSIFGSKPA-PGTLGT 431 G T+ S GS+P T+G+ Sbjct: 271 SKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Score = 40.4 bits (93), Expect = 0.008 Identities = 67/267 (25%), Positives = 96/267 (35%), Gaps = 50/267 (18%) Query: 229 GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP 288 GS+ T+S TG S TT + TA ST G T G Q T++ S Sbjct: 12 GSNTTTASTTG---SETTTILIKASETTTA---STAGSETTTPSPTGSQ----TTIVSIS 61 Query: 289 FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348 + TTT G S+ G G T AS + G+ T ST + T Sbjct: 62 GSEITTTSTAGSENTTVSSAGS---------GTTTAS----MAGSETTVSTAGSETTTVS 108 Query: 349 LFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408 + G T A+GS T +STTS+ + T++ G T S Sbjct: 109 ITGTETTMVSAMGSE--------TTTNSTTSSETTVTSTAG----------SETTTVSTV 150 Query: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468 G T T+ + + T + G+ T AG ++ P G T A Sbjct: 151 GSETTTAYTA-----DSETTAASTTGSEMTTVFTAGSETI----TPSTAGSETTTVSTAG 201 Query: 469 GFNTTTATLGFGAPQAPVALTDPNASA 495 TT +T G A A ++ A++ Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAAS 228 Score = 30.8 bits (68), Expect = 6.2 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 ++ T P+ + T S+ + A+ T+T + G+ T T + V + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 364 LFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFGFGTNTSGNSIF 420 +T GS +T S+ GTT+ + G++ T+ T G+ T T + GT T+ S Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI-TGTETTMVSAM 120 Query: 421 GSK 423 GS+ Sbjct: 121 GSE 123 >gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] Length = 1704 Score = 82.4 bits (202), Expect = 2e-15 Identities = 119/498 (23%), Positives = 195/498 (39%), Gaps = 47/498 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 858 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 918 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 973 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1143 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1144 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1198 Query: 477 LGFGAPQAPVALTDPNAS 494 G A + ++ N + Sbjct: 1199 AGSETTTASTSGSETNTA 1216 Score = 78.2 bits (191), Expect = 3e-14 Identities = 117/445 (26%), Positives = 172/445 (38%), Gaps = 57/445 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 608 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 + + +A G+ TT G GT + G + + ++ G TTT +T S Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-----GSETTTTSTEGSEI 722 Query: 304 NTSTIGQPSTNTMGLFG------------VTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 T++I T T G T AS G TA+ TS+ T T + G Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET---TMASIMG 779 Query: 352 QTNTGFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 T +GS T+F N TT S+T S + +T+G P T Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPAST 837 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSK 423 G+ T T+ G+ T+ S GS+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSE 862 Score = 76.3 bits (186), Expect = 1e-13 Identities = 139/569 (24%), Positives = 209/569 (36%), Gaps = 78/569 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 890 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160 Query: 375 SSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLG 434 S T++ + G+ + T T G+ T T++ G+ T+ S GS+ T + G Sbjct: 1161 SEATTSSAAGSEA------TTTSTEGSETTTASTA-GSETTTASTAGSET---TTASTSG 1210 Query: 435 AGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGAPQAP 485 + TA G + + P G AF G TT TAT G+ Sbjct: 1211 SETNTACTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGSETTT 1265 Query: 486 VALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALT 545 V++T A+AA V + P+ PMS R T P A ++T Sbjct: 1266 VSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSG-----TRTTGTRPTASSSVT 1320 Query: 546 TPTHYKLTPRPATRVRPK-ALQTTGTAKS 573 T A+ P L T+G S Sbjct: 1321 MAPGMDFTASAASHTVPGIVLNTSGLGTS 1349 Score = 75.9 bits (185), Expect = 2e-13 Identities = 118/504 (23%), Positives = 189/504 (37%), Gaps = 65/504 (12%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 323 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 324 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 374 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 489 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 490 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 543 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 544 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 363 TLFGNNKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNS 418 N +T S TTSA + G TT+ ++ T T G+ T T T S + Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT----VSTTDSETT 654 Query: 419 IFGSKPAPGTLGTGLGAGFGTALGAGQASLF-----GNNQPKIGGPLGTGAFGAPGFNTT 473 + + + T+ + G+ T G + G I G T TT Sbjct: 655 MVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 474 TATLGFGAPQAPVALTDPNASAAQ 497 T+T G A + ++ ++ + Sbjct: 715 TSTEGSEITTASITGSETTTASTE 738 Score = 68.6 bits (166), Expect = 3e-11 Identities = 94/400 (23%), Positives = 149/400 (37%), Gaps = 54/400 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S G T + SG T++ S NT S T + G+ + A S +T Sbjct: 47 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 + T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 ++ GS ++F S T P+ TT+ T +T ST H TA Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 S++ + + G+ TT GS +S S TN+ F Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268 Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311 T STTGF T G + +++ G TT STIG Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGPE 312 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T +S+ +F + T + G+ T + TG +++ G+ T Sbjct: 313 TTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETST 365 Query: 372 --TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405 Score = 67.8 bits (164), Expect = 5e-11 Identities = 126/505 (24%), Positives = 188/505 (37%), Gaps = 59/505 (11%) Query: 18 GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77 G+ T TG TT+ G+ +S L S T T + S + T+T Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965 Query: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136 G+ T TA+T +T ++ S A + ++ T + G+ T++ GT T Sbjct: 966 VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025 Query: 137 SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 ++ GS + ++ T A + TT + TG++T ST S T E Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246 + S +L + G AG TT + GS T+S G SS TT Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134 Query: 247 NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306 + + T F TT T G ++ TTS S +ATTT G S Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187 Query: 307 TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTL 364 T G +T +T G T AS G TA T + T+ + G +TNT F T Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAFIIGSETT 1244 Query: 365 FGN--------NKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNT-- 414 + LT ++T S + G T+ + T L T+ S TNT Sbjct: 1245 IASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI-TNTPM 1303 Query: 415 SGNSIFGSKP-APGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 SG G++P A ++ G F AS + P G L T G + Sbjct: 1304 SGTRTTGTRPTASSSVTMAPGMDF-------TASAASHTVP--GIVLNTSGLGTSTMGAS 1354 Query: 474 TATLGFGAPQAPVALTDPNASAAQQ 498 + T G + +P +S Q+ Sbjct: 1355 STTSAHGVRTTTGSTREPTSSTFQE 1379 Score = 66.2 bits (160), Expect = 1e-10 Identities = 106/441 (24%), Positives = 173/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 621 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT+ + G+ T+ + G++ T T G+ Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 742 TTTASTE-GSETTSASTTGSE 761 Score = 59.3 bits (142), Expect = 2e-08 Identities = 90/380 (23%), Positives = 152/380 (40%), Gaps = 53/380 (13%) Query: 71 PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122 PA ++T T + T L + T T+ S+ + PTG G+ T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +TS+ G TT +++ G+T+ S+ G S T + G+ TGT+T + + + + Sbjct: 67 TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242 +T S + E + + + VG+ TTT S T+++T Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173 Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 +T + + + G+ TT T +TT++ + G TTT +T S Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223 Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359 ST+G +T T S G A+ ++ T TAF + + TGF Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283 Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL------------TLGTNT 403 ++ G+ +T GS TT A + G TT ++ T T+G+ T Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343 Query: 404 NTSNFGFGTNTSGNSIFGSK 423 T + G+ T+ SI GS+ Sbjct: 344 TTVS-TTGSETTTASIMGSE 362 Score = 43.1 bits (100), Expect = 0.001 Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 71/331 (21%) Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188 G+ TT++ GS + ++ +S TA+ G+ PTG+ T + + + I+T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69 Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E + S G+GTTT S T S G S +TT Sbjct: 70 -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106 Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308 S TG T G + T+ S + T T G ST+ Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150 Query: 309 GQPSTNTMGLFGVTQASQPGG-----LFGTATNTSTGTAFGTGT---GLFGQTNTGFGAV 360 G +T T A+ G +F + T T + G+ T G T Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT 210 Query: 361 GSTLFG-------NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF--- 410 GS +T GS TT + G+ + T T + +N F Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTED 270 Query: 411 ---------GTNTSGNSIFGSKPA-PGTLGT 431 G T+ S GS+P T+G+ Sbjct: 271 SKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Score = 40.4 bits (93), Expect = 0.008 Identities = 67/267 (25%), Positives = 96/267 (35%), Gaps = 50/267 (18%) Query: 229 GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP 288 GS+ T+S TG S TT + TA ST G T G Q T++ S Sbjct: 12 GSNTTTASTTG---SETTTILIKASETTTA---STAGSETTTPSPTGSQ----TTIVSIS 61 Query: 289 FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348 + TTT G S+ G G T AS + G+ T ST + T Sbjct: 62 GSEITTTSTAGSENTTVSSAGS---------GTTTAS----MAGSETTVSTAGSETTTVS 108 Query: 349 LFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408 + G T A+GS T +STTS+ + T++ G T S Sbjct: 109 ITGTETTMVSAMGSE--------TTTNSTTSSETTVTSTAG----------SETTTVSTV 150 Query: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468 G T T+ + + T + G+ T AG ++ P G T A Sbjct: 151 GSETTTAYTA-----DSETTAASTTGSEMTTVFTAGSETI----TPSTAGSETTTVSTAG 201 Query: 469 GFNTTTATLGFGAPQAPVALTDPNASA 495 TT +T G A A ++ A++ Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAAS 228 Score = 30.8 bits (68), Expect = 6.2 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 ++ T P+ + T S+ + A+ T+T + G+ T T + V + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 364 LFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFGFGTNTSGNSIF 420 +T GS +T S+ GTT+ + G++ T+ T G+ T T + GT T+ S Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI-TGTETTMVSAM 120 Query: 421 GSK 423 GS+ Sbjct: 121 GSE 123 >gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 82.4 bits (202), Expect = 2e-15 Identities = 119/498 (23%), Positives = 195/498 (39%), Gaps = 47/498 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 858 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 918 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 973 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1143 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1144 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1198 Query: 477 LGFGAPQAPVALTDPNAS 494 G A + ++ N + Sbjct: 1199 AGSETTTASTSGSETNTA 1216 Score = 78.2 bits (191), Expect = 3e-14 Identities = 117/445 (26%), Positives = 172/445 (38%), Gaps = 57/445 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 608 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 + + +A G+ TT G GT + G + + ++ G TTT +T S Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-----GSETTTTSTEGSEI 722 Query: 304 NTSTIGQPSTNTMGLFG------------VTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 T++I T T G T AS G TA+ TS+ T T + G Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET---TMASIMG 779 Query: 352 QTNTGFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 T +GS T+F N TT S+T S + +T+G P T Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPAST 837 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSK 423 G+ T T+ G+ T+ S GS+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSE 862 Score = 75.9 bits (185), Expect = 2e-13 Identities = 118/504 (23%), Positives = 189/504 (37%), Gaps = 65/504 (12%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 323 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 324 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 374 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 489 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 490 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 543 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 544 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 363 TLFGNNKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNS 418 N +T S TTSA + G TT+ ++ T T G+ T T T S + Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT----VSTTDSETT 654 Query: 419 IFGSKPAPGTLGTGLGAGFGTALGAGQASLF-----GNNQPKIGGPLGTGAFGAPGFNTT 473 + + + T+ + G+ T G + G I G T TT Sbjct: 655 MVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 474 TATLGFGAPQAPVALTDPNASAAQ 497 T+T G A + ++ ++ + Sbjct: 715 TSTEGSEITTASITGSETTTASTE 738 Score = 74.3 bits (181), Expect = 5e-13 Identities = 101/431 (23%), Positives = 167/431 (38%), Gaps = 31/431 (7%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 T ST T TT G T++ S T S+T G+ ++ S + T+ Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNT 135 T G+ T TA+T +T ++ S A+ ++ T G+ T++ G+ T Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV---KAGVSTNISTKHQCIT 190 T + GS T+ S+ G + T + TG+ TGT+T + + +T ++T T Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1044 Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250 A+ Y + S E + +G + TT GS T+S L +++ + SG Sbjct: 1045 AV--YTTGS------ETTTTSTEGSET-----TTVSTTGSETTTASTADLETTTVSTSGS 1091 Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310 TA +TT + T + S + TT TG T Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151 Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 +T + S G T T+T T TA G+ + G ++ G+ Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGS 1211 Query: 368 --NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTLTLGTN---TNTSNFGFGTNTSGNSIF 420 N T GS T++ S G T + + G++ T+ + T TS G T T + Sbjct: 1212 ETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 421 GSKPAPGTLGT 431 G+ A T+ + Sbjct: 1272 GATAASTTVSS 1282 Score = 72.8 bits (177), Expect = 1e-12 Identities = 136/568 (23%), Positives = 208/568 (36%), Gaps = 76/568 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 890 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160 Query: 375 SSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLG 434 S T++ + G+ + T T G+ T T++ G+ T+ S GS+ T + G Sbjct: 1161 SEATTSSAAGSEA------TTTSTEGSETTTASTA-GSETTTASTAGSET---TTASTSG 1210 Query: 435 AGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNT--------TTATLGFGAPQAPV 486 + TA G + + P G AF +T TAT G+ V Sbjct: 1211 SETNTACTTGSET----STPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTV 1266 Query: 487 ALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTT 546 ++T A+AA V + P+ PMS + RL A ++T Sbjct: 1267 SITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTM 1321 Query: 547 PTHYKLTPRPATRVRPK-ALQTTGTAKS 573 T A+ P L T+G S Sbjct: 1322 APGMDFTASAASHTVPGIVLNTSGLGTS 1349 Score = 68.6 bits (166), Expect = 3e-11 Identities = 94/400 (23%), Positives = 149/400 (37%), Gaps = 54/400 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S G T + SG T++ S NT S T + G+ + A S +T Sbjct: 47 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 + T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 ++ GS ++F S T P+ TT+ T +T ST H TA Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 S++ + + G+ TT GS +S S TN+ F Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268 Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311 T STTGF T G + +++ G TT STIG Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGPE 312 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T +S+ +F + T + G+ T + TG +++ G+ T Sbjct: 313 TTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETST 365 Query: 372 --TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405 Score = 67.4 bits (163), Expect = 6e-11 Identities = 129/505 (25%), Positives = 190/505 (37%), Gaps = 59/505 (11%) Query: 18 GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77 G+ T TG TT+ G+ +S L S T T + S + T+T Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965 Query: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136 G+ T TA+T +T ++ S A + ++ T + G+ T++ GT T Sbjct: 966 VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025 Query: 137 SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 ++ GS + ++ T A + TT + TG++T ST S T E Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246 + S +L + G AG TT + GS T+S G SS TT Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134 Query: 247 NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306 + + T F TT T G ++ TTS S +ATTT G S Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187 Query: 307 TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF-----GA 359 T G +T +T G T AS G TA T + T+ + G +TNT F Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAFIIGSEST 1244 Query: 360 VGSTLFGNNKLTTF-GSSTT--SAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSG 416 + ST T+ GS TT S + G T+ + T L T+ S TNT Sbjct: 1245 IASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI-TNT-- 1301 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 + G++ T GT L A + G AS + P G L T G + Sbjct: 1302 -PMSGTR----TTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGAS 1354 Query: 474 TATLGFGAPQAPVALTDPNASAAQQ 498 + T G + +P +S Q+ Sbjct: 1355 STTSAHGVRTTTGSTREPTSSTFQE 1379 Score = 66.2 bits (160), Expect = 1e-10 Identities = 106/441 (24%), Positives = 173/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 621 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT+ + G+ T+ + G++ T T G+ Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 742 TTTASTE-GSETTSASTTGSE 761 Score = 59.3 bits (142), Expect = 2e-08 Identities = 90/380 (23%), Positives = 152/380 (40%), Gaps = 53/380 (13%) Query: 71 PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122 PA ++T T + T L + T T+ S+ + PTG G+ T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +TS+ G TT +++ G+T+ S+ G S T + G+ TGT+T + + + + Sbjct: 67 TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242 +T S + E + + + VG+ TTT S T+++T Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173 Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 +T + + + G+ TT T +TT++ + G TTT +T S Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223 Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359 ST+G +T T S G A+ ++ T TAF + + TGF Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283 Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL------------TLGTNT 403 ++ G+ +T GS TT A + G TT ++ T T+G+ T Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343 Query: 404 NTSNFGFGTNTSGNSIFGSK 423 T + G+ T+ SI GS+ Sbjct: 344 TTVS-TTGSETTTASIMGSE 362 Score = 43.1 bits (100), Expect = 0.001 Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 71/331 (21%) Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188 G+ TT++ GS + ++ +S TA+ G+ PTG+ T + + + I+T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69 Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E + S G+GTTT S T S G S +TT Sbjct: 70 -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106 Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308 S TG T G + T+ S + T T G ST+ Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150 Query: 309 GQPSTNTMGLFGVTQASQPGG-----LFGTATNTSTGTAFGTGT---GLFGQTNTGFGAV 360 G +T T A+ G +F + T T + G+ T G T Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT 210 Query: 361 GSTLFG-------NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF--- 410 GS +T GS TT + G+ + T T + +N F Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTED 270 Query: 411 ---------GTNTSGNSIFGSKPA-PGTLGT 431 G T+ S GS+P T+G+ Sbjct: 271 SKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Score = 40.4 bits (93), Expect = 0.008 Identities = 67/267 (25%), Positives = 96/267 (35%), Gaps = 50/267 (18%) Query: 229 GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP 288 GS+ T+S TG S TT + TA ST G T G Q T++ S Sbjct: 12 GSNTTTASTTG---SETTTILIKASETTTA---STAGSETTTPSPTGSQ----TTIVSIS 61 Query: 289 FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348 + TTT G S+ G G T AS + G+ T ST + T Sbjct: 62 GSEITTTSTAGSENTTVSSAGS---------GTTTAS----MAGSETTVSTAGSETTTVS 108 Query: 349 LFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408 + G T A+GS T +STTS+ + T++ G T S Sbjct: 109 ITGTETTMVSAMGSE--------TTTNSTTSSETTVTSTAG----------SETTTVSTV 150 Query: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468 G T T+ + + T + G+ T AG ++ P G T A Sbjct: 151 GSETTTAYTA-----DSETTAASTTGSEMTTVFTAGSETI----TPSTAGSETTTVSTAG 201 Query: 469 GFNTTTATLGFGAPQAPVALTDPNASA 495 TT +T G A A ++ A++ Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAAS 228 Score = 30.8 bits (68), Expect = 6.2 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 ++ T P+ + T S+ + A+ T+T + G+ T T + V + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 364 LFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFGFGTNTSGNSIF 420 +T GS +T S+ GTT+ + G++ T+ T G+ T T + GT T+ S Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI-TGTETTMVSAM 120 Query: 421 GSK 423 GS+ Sbjct: 121 GSE 123 >gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 81.6 bits (200), Expect = 3e-15 Identities = 119/491 (24%), Positives = 191/491 (38%), Gaps = 47/491 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 858 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 918 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 973 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1143 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1144 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1198 Query: 477 LGFGAPQAPVA 487 G A A Sbjct: 1199 AGSETTTASTA 1209 Score = 78.2 bits (191), Expect = 3e-14 Identities = 117/445 (26%), Positives = 172/445 (38%), Gaps = 57/445 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 608 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 + + +A G+ TT G GT + G + + ++ G TTT +T S Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-----GSETTTTSTEGSEI 722 Query: 304 NTSTIGQPSTNTMGLFG------------VTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 T++I T T G T AS G TA+ TS+ T T + G Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET---TMASIMG 779 Query: 352 QTNTGFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 T +GS T+F N TT S+T S + +T+G P T Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPAST 837 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSK 423 G+ T T+ G+ T+ S GS+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSE 862 Score = 76.6 bits (187), Expect = 1e-13 Identities = 100/406 (24%), Positives = 160/406 (39%), Gaps = 33/406 (8%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 T ST T TT G T++ S T S+T G+ ++ S + T+ Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNT 135 T G+ T TA+T +T ++ S A+ ++ T G+ T++ G+ T Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV---KAGVSTNISTKHQCIT 190 T + GS T+ S+ G + T + TG+ TGT+T + + +T ++T T Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1044 Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250 A+ Y + S E + +G + TT GS T+S L +++ + SG Sbjct: 1045 AV--YTTGS------ETTTTSTEGSET-----TTVSTTGSETTTASTADLETTTVSTSGS 1091 Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310 TA +TT + T + S + TT TG T Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT-V 1150 Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKL 370 T T+ G ++A+ AT TST + T G T GS Sbjct: 1151 SETTTVSTIG-SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE---TTTA 1206 Query: 371 TTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNT-SNFGFGTNTS 415 +T GS TT+A + G+ + T G+ T+T S+ G TNT+ Sbjct: 1207 STAGSETTTASTSGSET------NTACTTGSETSTPSSAGSETNTA 1246 Score = 75.9 bits (185), Expect = 2e-13 Identities = 118/504 (23%), Positives = 189/504 (37%), Gaps = 65/504 (12%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 323 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 324 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 374 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 489 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 490 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 543 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 544 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 363 TLFGNNKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNS 418 N +T S TTSA + G TT+ ++ T T G+ T T T S + Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT----VSTTDSETT 654 Query: 419 IFGSKPAPGTLGTGLGAGFGTALGAGQASLF-----GNNQPKIGGPLGTGAFGAPGFNTT 473 + + + T+ + G+ T G + G I G T TT Sbjct: 655 MVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 474 TATLGFGAPQAPVALTDPNASAAQ 497 T+T G A + ++ ++ + Sbjct: 715 TSTEGSEITTASITGSETTTASTE 738 Score = 74.7 bits (182), Expect = 4e-13 Identities = 140/573 (24%), Positives = 213/573 (37%), Gaps = 76/573 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 890 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160 Query: 375 SSTTSAPSFGT--TSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLG 430 S T++ + G+ T+ G++ T T G+ T T++ G+ T+ S GS+ T Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTA-GSETTTASTAGSET---TTA 1216 Query: 431 TGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGA 481 + G+ TA G + + P G AF G TT TAT G+ Sbjct: 1217 STSGSETNTACTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGS 1271 Query: 482 PQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQ 541 V++T A+AA V + P+ PMS + RL A Sbjct: 1272 ETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TAS 1326 Query: 542 KALTTPTHYKLTPRPATRVRPK-ALQTTGTAKS 573 ++T T A+ P L T+G S Sbjct: 1327 SSVTMAPGMDFTASAASHTVPGIVLNTSGLGTS 1359 Score = 74.3 bits (181), Expect = 5e-13 Identities = 125/515 (24%), Positives = 182/515 (35%), Gaps = 55/515 (10%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 TTST G T +T G T + S T S+T G+ ++ S + T Sbjct: 895 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 954 Query: 77 TGFGFGTSTGTANTLFG---TASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133 T G+ T T T+ TAST S ++ + A ++ T+T S TT Sbjct: 955 TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 134 NTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 ++ +T S G + T G+ TG++T ST S T Sbjct: 1015 TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT---TSTEGSETTTVSTTGS 1071 Query: 194 EYESKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSS 243 E + S +L + G AG TT + GS T+S G SS Sbjct: 1072 ETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS 1131 Query: 244 STTNSGFAYGQNKTAFGT-------STTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQ 296 TT + + T F T ST G G + T++ G TTT Sbjct: 1132 ETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE-----GSETTTA 1186 Query: 297 NTGFSFGNTSTIGQPSTNTMGLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTN 354 +T S T++ T T G T AS G TA T + T+ + G +TN Sbjct: 1187 STAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG--SETN 1244 Query: 355 TGFGAVGSTLFGN--------NKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTS 406 T F T + LT ++T S + G T+ + T L T+ S Sbjct: 1245 TAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVS 1304 Query: 407 NFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTG 463 TNT + G++ T GT L A + G AS + P G L T Sbjct: 1305 IQPI-TNT---PMSGTR----TTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTS 1354 Query: 464 AFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 498 G ++ T G + +P +S Q+ Sbjct: 1355 GLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQE 1389 Score = 68.6 bits (166), Expect = 3e-11 Identities = 94/400 (23%), Positives = 149/400 (37%), Gaps = 54/400 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S G T + SG T++ S NT S T + G+ + A S +T Sbjct: 47 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 + T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 ++ GS ++F S T P+ TT+ T +T ST H TA Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 S++ + + G+ TT GS +S S TN+ F Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268 Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311 T STTGF T G + +++ G TT STIG Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGPE 312 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T +S+ +F + T + G+ T + TG +++ G+ T Sbjct: 313 TTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETST 365 Query: 372 --TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405 Score = 66.2 bits (160), Expect = 1e-10 Identities = 106/441 (24%), Positives = 173/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 621 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT+ + G+ T+ + G++ T T G+ Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 742 TTTASTE-GSETTSASTTGSE 761 Score = 59.3 bits (142), Expect = 2e-08 Identities = 90/380 (23%), Positives = 152/380 (40%), Gaps = 53/380 (13%) Query: 71 PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122 PA ++T T + T L + T T+ S+ + PTG G+ T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +TS+ G TT +++ G+T+ S+ G S T + G+ TGT+T + + + + Sbjct: 67 TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242 +T S + E + + + VG+ TTT S T+++T Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173 Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 +T + + + G+ TT T +TT++ + G TTT +T S Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223 Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359 ST+G +T T S G A+ ++ T TAF + + TGF Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283 Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL------------TLGTNT 403 ++ G+ +T GS TT A + G TT ++ T T+G+ T Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343 Query: 404 NTSNFGFGTNTSGNSIFGSK 423 T + G+ T+ SI GS+ Sbjct: 344 TTVS-TTGSETTTASIMGSE 362 Score = 43.1 bits (100), Expect = 0.001 Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 71/331 (21%) Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188 G+ TT++ GS + ++ +S TA+ G+ PTG+ T + + + I+T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69 Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E + S G+GTTT S T S G S +TT Sbjct: 70 -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106 Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308 S TG T G + T+ S + T T G ST+ Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150 Query: 309 GQPSTNTMGLFGVTQASQPGG-----LFGTATNTSTGTAFGTGT---GLFGQTNTGFGAV 360 G +T T A+ G +F + T T + G+ T G T Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT 210 Query: 361 GSTLFG-------NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF--- 410 GS +T GS TT + G+ + T T + +N F Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTED 270 Query: 411 ---------GTNTSGNSIFGSKPA-PGTLGT 431 G T+ S GS+P T+G+ Sbjct: 271 SKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Score = 40.4 bits (93), Expect = 0.008 Identities = 67/267 (25%), Positives = 96/267 (35%), Gaps = 50/267 (18%) Query: 229 GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP 288 GS+ T+S TG S TT + TA ST G T G Q T++ S Sbjct: 12 GSNTTTASTTG---SETTTILIKASETTTA---STAGSETTTPSPTGSQ----TTIVSIS 61 Query: 289 FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348 + TTT G S+ G G T AS + G+ T ST + T Sbjct: 62 GSEITTTSTAGSENTTVSSAGS---------GTTTAS----MAGSETTVSTAGSETTTVS 108 Query: 349 LFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408 + G T A+GS T +STTS+ + T++ G T S Sbjct: 109 ITGTETTMVSAMGSE--------TTTNSTTSSETTVTSTAG----------SETTTVSTV 150 Query: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468 G T T+ + + T + G+ T AG ++ P G T A Sbjct: 151 GSETTTAYTA-----DSETTAASTTGSEMTTVFTAGSETI----TPSTAGSETTTVSTAG 201 Query: 469 GFNTTTATLGFGAPQAPVALTDPNASA 495 TT +T G A A ++ A++ Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAAS 228 Score = 30.8 bits (68), Expect = 6.2 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 ++ T P+ + T S+ + A+ T+T + G+ T T + V + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 364 LFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFGFGTNTSGNSIF 420 +T GS +T S+ GTT+ + G++ T+ T G+ T T + GT T+ S Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI-TGTETTMVSAM 120 Query: 421 GSK 423 GS+ Sbjct: 121 GSE 123 >gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 81.6 bits (200), Expect = 3e-15 Identities = 119/491 (24%), Positives = 191/491 (38%), Gaps = 47/491 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 858 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 918 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 973 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1143 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1144 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1198 Query: 477 LGFGAPQAPVA 487 G A A Sbjct: 1199 AGSETTTASTA 1209 Score = 78.2 bits (191), Expect = 3e-14 Identities = 117/445 (26%), Positives = 172/445 (38%), Gaps = 57/445 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 608 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 + + +A G+ TT G GT + G + + ++ G TTT +T S Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-----GSETTTTSTEGSEI 722 Query: 304 NTSTIGQPSTNTMGLFG------------VTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 T++I T T G T AS G TA+ TS+ T T + G Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET---TMASIMG 779 Query: 352 QTNTGFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 T +GS T+F N TT S+T S + +T+G P T Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPAST 837 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSK 423 G+ T T+ G+ T+ S GS+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSE 862 Score = 76.6 bits (187), Expect = 1e-13 Identities = 100/406 (24%), Positives = 160/406 (39%), Gaps = 33/406 (8%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 T ST T TT G T++ S T S+T G+ ++ S + T+ Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNT 135 T G+ T TA+T +T ++ S A+ ++ T G+ T++ G+ T Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV---KAGVSTNISTKHQCIT 190 T + GS T+ S+ G + T + TG+ TGT+T + + +T ++T T Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1044 Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250 A+ Y + S E + +G + TT GS T+S L +++ + SG Sbjct: 1045 AV--YTTGS------ETTTTSTEGSET-----TTVSTTGSETTTASTADLETTTVSTSGS 1091 Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310 TA +TT + T + S + TT TG T Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT-V 1150 Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKL 370 T T+ G ++A+ AT TST + T G T GS Sbjct: 1151 SETTTVSTIG-SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE---TTTA 1206 Query: 371 TTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNT-SNFGFGTNTS 415 +T GS TT+A + G+ + T G+ T+T S+ G TNT+ Sbjct: 1207 STAGSETTTASTSGSET------NTACTTGSETSTPSSAGSETNTA 1246 Score = 75.9 bits (185), Expect = 2e-13 Identities = 118/504 (23%), Positives = 189/504 (37%), Gaps = 65/504 (12%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 323 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 324 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 374 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 489 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 490 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 543 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 544 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 363 TLFGNNKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNS 418 N +T S TTSA + G TT+ ++ T T G+ T T T S + Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT----VSTTDSETT 654 Query: 419 IFGSKPAPGTLGTGLGAGFGTALGAGQASLF-----GNNQPKIGGPLGTGAFGAPGFNTT 473 + + + T+ + G+ T G + G I G T TT Sbjct: 655 MVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 474 TATLGFGAPQAPVALTDPNASAAQ 497 T+T G A + ++ ++ + Sbjct: 715 TSTEGSEITTASITGSETTTASTE 738 Score = 74.7 bits (182), Expect = 4e-13 Identities = 140/573 (24%), Positives = 213/573 (37%), Gaps = 76/573 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 890 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160 Query: 375 SSTTSAPSFGT--TSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLG 430 S T++ + G+ T+ G++ T T G+ T T++ G+ T+ S GS+ T Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTA-GSETTTASTAGSET---TTA 1216 Query: 431 TGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGA 481 + G+ TA G + + P G AF G TT TAT G+ Sbjct: 1217 STSGSETNTACTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGS 1271 Query: 482 PQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQ 541 V++T A+AA V + P+ PMS + RL A Sbjct: 1272 ETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TAS 1326 Query: 542 KALTTPTHYKLTPRPATRVRPK-ALQTTGTAKS 573 ++T T A+ P L T+G S Sbjct: 1327 SSVTMAPGMDFTASAASHTVPGIVLNTSGLGTS 1359 Score = 74.3 bits (181), Expect = 5e-13 Identities = 125/515 (24%), Positives = 182/515 (35%), Gaps = 55/515 (10%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 TTST G T +T G T + S T S+T G+ ++ S + T Sbjct: 895 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 954 Query: 77 TGFGFGTSTGTANTLFG---TASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133 T G+ T T T+ TAST S ++ + A ++ T+T S TT Sbjct: 955 TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 134 NTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 ++ +T S G + T G+ TG++T ST S T Sbjct: 1015 TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT---TSTEGSETTTVSTTGS 1071 Query: 194 EYESKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSS 243 E + S +L + G AG TT + GS T+S G SS Sbjct: 1072 ETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS 1131 Query: 244 STTNSGFAYGQNKTAFGT-------STTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQ 296 TT + + T F T ST G G + T++ G TTT Sbjct: 1132 ETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE-----GSETTTA 1186 Query: 297 NTGFSFGNTSTIGQPSTNTMGLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTN 354 +T S T++ T T G T AS G TA T + T+ + G +TN Sbjct: 1187 STAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG--SETN 1244 Query: 355 TGFGAVGSTLFGN--------NKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTS 406 T F T + LT ++T S + G T+ + T L T+ S Sbjct: 1245 TAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVS 1304 Query: 407 NFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTG 463 TNT + G++ T GT L A + G AS + P G L T Sbjct: 1305 IQPI-TNT---PMSGTR----TTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTS 1354 Query: 464 AFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 498 G ++ T G + +P +S Q+ Sbjct: 1355 GLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQE 1389 Score = 68.6 bits (166), Expect = 3e-11 Identities = 94/400 (23%), Positives = 149/400 (37%), Gaps = 54/400 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S G T + SG T++ S NT S T + G+ + A S +T Sbjct: 47 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 + T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 ++ GS ++F S T P+ TT+ T +T ST H TA Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 S++ + + G+ TT GS +S S TN+ F Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268 Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311 T STTGF T G + +++ G TT STIG Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGPE 312 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T +S+ +F + T + G+ T + TG +++ G+ T Sbjct: 313 TTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETST 365 Query: 372 --TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405 Score = 66.2 bits (160), Expect = 1e-10 Identities = 106/441 (24%), Positives = 173/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 621 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT+ + G+ T+ + G++ T T G+ Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 742 TTTASTE-GSETTSASTTGSE 761 Score = 59.3 bits (142), Expect = 2e-08 Identities = 90/380 (23%), Positives = 152/380 (40%), Gaps = 53/380 (13%) Query: 71 PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122 PA ++T T + T L + T T+ S+ + PTG G+ T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +TS+ G TT +++ G+T+ S+ G S T + G+ TGT+T + + + + Sbjct: 67 TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242 +T S + E + + + VG+ TTT S T+++T Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173 Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 +T + + + G+ TT T +TT++ + G TTT +T S Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223 Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359 ST+G +T T S G A+ ++ T TAF + + TGF Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283 Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL------------TLGTNT 403 ++ G+ +T GS TT A + G TT ++ T T+G+ T Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343 Query: 404 NTSNFGFGTNTSGNSIFGSK 423 T + G+ T+ SI GS+ Sbjct: 344 TTVS-TTGSETTTASIMGSE 362 Score = 43.1 bits (100), Expect = 0.001 Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 71/331 (21%) Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188 G+ TT++ GS + ++ +S TA+ G+ PTG+ T + + + I+T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69 Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E + S G+GTTT S T S G S +TT Sbjct: 70 -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106 Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308 S TG T G + T+ S + T T G ST+ Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150 Query: 309 GQPSTNTMGLFGVTQASQPGG-----LFGTATNTSTGTAFGTGT---GLFGQTNTGFGAV 360 G +T T A+ G +F + T T + G+ T G T Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT 210 Query: 361 GSTLFG-------NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF--- 410 GS +T GS TT + G+ + T T + +N F Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTED 270 Query: 411 ---------GTNTSGNSIFGSKPA-PGTLGT 431 G T+ S GS+P T+G+ Sbjct: 271 SKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Score = 40.4 bits (93), Expect = 0.008 Identities = 67/267 (25%), Positives = 96/267 (35%), Gaps = 50/267 (18%) Query: 229 GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP 288 GS+ T+S TG S TT + TA ST G T G Q T++ S Sbjct: 12 GSNTTTASTTG---SETTTILIKASETTTA---STAGSETTTPSPTGSQ----TTIVSIS 61 Query: 289 FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348 + TTT G S+ G G T AS + G+ T ST + T Sbjct: 62 GSEITTTSTAGSENTTVSSAGS---------GTTTAS----MAGSETTVSTAGSETTTVS 108 Query: 349 LFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408 + G T A+GS T +STTS+ + T++ G T S Sbjct: 109 ITGTETTMVSAMGSE--------TTTNSTTSSETTVTSTAG----------SETTTVSTV 150 Query: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468 G T T+ + + T + G+ T AG ++ P G T A Sbjct: 151 GSETTTAYTA-----DSETTAASTTGSEMTTVFTAGSETI----TPSTAGSETTTVSTAG 201 Query: 469 GFNTTTATLGFGAPQAPVALTDPNASA 495 TT +T G A A ++ A++ Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAAS 228 Score = 30.8 bits (68), Expect = 6.2 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 ++ T P+ + T S+ + A+ T+T + G+ T T + V + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 364 LFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFGFGTNTSGNSIF 420 +T GS +T S+ GTT+ + G++ T+ T G+ T T + GT T+ S Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI-TGTETTMVSAM 120 Query: 421 GSK 423 GS+ Sbjct: 121 GSE 123 >gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 81.6 bits (200), Expect = 3e-15 Identities = 119/491 (24%), Positives = 191/491 (38%), Gaps = 47/491 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T ST G T +T+G T++ SS T S+T G+ + T ST Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+ T N+ AST S ++ + A ++ P T+T++ G+ TT++ Sbjct: 799 SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857 Query: 139 PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 GS T+ S + TA G TT T T + +T ST+ IT + Sbjct: 858 TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917 Query: 194 E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 E+ + E A+ +G + TT GS T SA G +++ T G Sbjct: 918 TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972 Query: 252 YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307 TA +TT G T + G + T+ S + TT TG TST Sbjct: 973 TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028 Query: 308 IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367 G +T T S+ ++ T + T+T + G+ T T + + Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083 Query: 368 NKLTTFGSSTTSAPSFG--TTSGGLFGNKPT---------LTLGTNTNTSNFGFGTNTSG 416 ++T GS TT+A + G TT+ + G+K T T+ T ++ + T + Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEM 1143 Query: 417 NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTAT 476 ++F + T+ T +G+ T+ AG + + + G T A A TT +T Sbjct: 1144 TTVFTTVSETTTVST-IGSEATTSSAAGSEATTTSTE----GSETTTASTAGSETTTAST 1198 Query: 477 LGFGAPQAPVA 487 G A A Sbjct: 1199 AGSETTTASTA 1209 Score = 78.2 bits (191), Expect = 3e-14 Identities = 117/445 (26%), Positives = 172/445 (38%), Gaps = 57/445 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76 T ST G +TS T++ S T S+TK G T++ S T+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 T F G+ T TA+T G+ +T S S+ + G+ T+ S+ G TT +T Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAG-----VSTNISTKHQCI 189 + +T+ S G T + TG TT +GT AG VST S Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607 Query: 190 TAMKEYESKSL--EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTN 247 TA E S S E ++ + G+ TTT S T +T + T+ Sbjct: 608 TADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667 Query: 248 SGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 + + +A G+ TT G GT + G + + ++ G TTT +T S Sbjct: 668 TEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTT-----GSETTTTSTEGSEI 722 Query: 304 NTSTIGQPSTNTMGLFG------------VTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 T++I T T G T AS G TA+ TS+ T T + G Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSET---TMASIMG 779 Query: 352 QTNTGFGAVGS-------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT 398 T +GS T+F N TT S+T S + +T+G P T Sbjct: 780 SETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS--ETIPAST 837 Query: 399 LGTNTNTSNFGFGTNTSGNSIFGSK 423 G+ T T+ G+ T+ S GS+ Sbjct: 838 AGSETTTTTSTEGSETTTASTEGSE 862 Score = 76.6 bits (187), Expect = 1e-13 Identities = 100/406 (24%), Positives = 160/406 (39%), Gaps = 33/406 (8%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 T ST T TT G T++ S T S+T G+ ++ S + T+ Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924 Query: 77 TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNT 135 T G+ T TA+T +T ++ S A+ ++ T G+ T++ G+ T Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV---KAGVSTNISTKHQCIT 190 T + GS T+ S+ G + T + TG+ TGT+T + + +T ++T T Sbjct: 985 TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1044 Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250 A+ Y + S E + +G + TT GS T+S L +++ + SG Sbjct: 1045 AV--YTTGS------ETTTTSTEGSET-----TTVSTTGSETTTASTADLETTTVSTSGS 1091 Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310 TA +TT + T + S + TT TG T Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT-V 1150 Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKL 370 T T+ G ++A+ AT TST + T G T GS Sbjct: 1151 SETTTVSTIG-SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSE---TTTA 1206 Query: 371 TTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNT-SNFGFGTNTS 415 +T GS TT+A + G+ + T G+ T+T S+ G TNT+ Sbjct: 1207 STAGSETTTASTSGSET------NTACTTGSETSTPSSAGSETNTA 1246 Score = 75.9 bits (185), Expect = 2e-13 Identities = 118/504 (23%), Positives = 189/504 (37%), Gaps = 65/504 (12%) Query: 21 STFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATST 75 +T TGF TT+ G+ S GS G TK S ++ Sbjct: 273 TTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK---------VSTASSEV 323 Query: 76 STGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135 +T F G+ T A+T+ G+ +T S S+ T G+ TS+ G+ T Sbjct: 324 TTVFAAGSETIRASTV-GSETTTVSTTGSET--------TTASIMGSETSTDSTTGSETT 374 Query: 136 TSNPFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTK-HQCI 189 T++ GS T+ S G + T + TG TT+ T T + T +ST + Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434 Query: 190 TAMKEYESKSLEELR-LEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E ++ E A+ +G + TT GS T+ TG +++ +N+ Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSET-----TTVTTAGSETKTAYTTGSETTTASNT 489 Query: 249 G------FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 G F G + T T G+ + ++ TT S + TT TG Sbjct: 490 GLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTT--VSTEGSENTTVSTTGSET 543 Query: 303 GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS 362 ST G +T T T+ S+ + T T+T + G+GT + V + Sbjct: 544 TTVSTTGLETTTTS-----TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 363 TLFGNNKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNS 418 N +T S TTSA + G TT+ ++ T T G+ T T T S + Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTT----VSTTDSETT 654 Query: 419 IFGSKPAPGTLGTGLGAGFGTALGAGQASLF-----GNNQPKIGGPLGTGAFGAPGFNTT 473 + + + T+ + G+ T G + G I G T TT Sbjct: 655 MVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 474 TATLGFGAPQAPVALTDPNASAAQ 497 T+T G A + ++ ++ + Sbjct: 715 TSTEGSEITTASITGSETTTASTE 738 Score = 74.7 bits (182), Expect = 4e-13 Identities = 140/573 (24%), Positives = 213/573 (37%), Gaps = 76/573 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTST G T +T G T++ SS T S+T T+ ST Sbjct: 845 TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 T+T T + TAST S + T G+ T++ G+ TT++ Sbjct: 890 GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937 Query: 139 PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196 GS T+ S G + T + G+ G++T + + +T TA E Sbjct: 938 TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994 Query: 197 SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256 + S+E + GT T + S+ + + T + S T + + G Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053 Query: 257 TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316 T TST G T G + T+ S + TT +G ST G T T+ Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106 Query: 317 GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374 + G T AS G T + TS+ T + TG + T F V T ++T G Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160 Query: 375 SSTTSAPSFGT--TSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLG 430 S T++ + G+ T+ G++ T T G+ T T++ G+ T+ S GS+ T Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTA-GSETTTASTAGSET---TTA 1216 Query: 431 TGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGA 481 + G+ TA G + + P G AF G TT TAT G+ Sbjct: 1217 STSGSETNTACTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGS 1271 Query: 482 PQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQ 541 V++T A+AA V + P+ PMS + RL A Sbjct: 1272 ETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TAS 1326 Query: 542 KALTTPTHYKLTPRPATRVRPK-ALQTTGTAKS 573 ++T T A+ P L T+G S Sbjct: 1327 SSVTMAPGMDFTASAASHTVPGIVLNTSGLGTS 1359 Score = 74.3 bits (181), Expect = 5e-13 Identities = 125/515 (24%), Positives = 182/515 (35%), Gaps = 55/515 (10%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76 TTST G T +T G T + S T S+T G+ ++ S + T Sbjct: 895 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETI 954 Query: 77 TGFGFGTSTGTANTLFG---TASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133 T G+ T T T+ TAST S ++ + A ++ T+T S TT Sbjct: 955 TVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 134 NTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193 ++ +T S G + T G+ TG++T ST S T Sbjct: 1015 TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTT---TSTEGSETTTVSTTGS 1071 Query: 194 EYESKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSS 243 E + S +L + G AG TT + GS T+S G SS Sbjct: 1072 ETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSS 1131 Query: 244 STTNSGFAYGQNKTAFGT-------STTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQ 296 TT + + T F T ST G G + T++ G TTT Sbjct: 1132 ETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE-----GSETTTA 1186 Query: 297 NTGFSFGNTSTIGQPSTNTMGLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTN 354 +T S T++ T T G T AS G TA T + T+ + G +TN Sbjct: 1187 STAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG--SETN 1244 Query: 355 TGFGAVGSTLFGN--------NKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTS 406 T F T + LT ++T S + G T+ + T L T+ S Sbjct: 1245 TAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVS 1304 Query: 407 NFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTG 463 TNT + G++ T GT L A + G AS + P G L T Sbjct: 1305 IQPI-TNT---PMSGTR----TTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTS 1354 Query: 464 AFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 498 G ++ T G + +P +S Q+ Sbjct: 1355 GLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQE 1389 Score = 68.6 bits (166), Expect = 3e-11 Identities = 94/400 (23%), Positives = 149/400 (37%), Gaps = 54/400 (13%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S G T + SG T++ S NT S T + G+ + A S +T Sbjct: 47 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136 + T + G+ +T S SS+ + A ++ T G+ T++ + T Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166 Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 ++ GS ++F S T P+ TT+ T +T ST H TA Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251 S++ + + G+ TT GS +S S TN+ F Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268 Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311 T STTGF T G + +++ G TT STIG Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTM---------ASTIGPE 312 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 +T T +S+ +F + T + G+ T + TG +++ G+ T Sbjct: 313 TTKVS-----TASSEVTTVFAAGSETIRASTVGSETTTV--STTGSETTTASIMGSETST 365 Query: 372 --TFGSSTTSAPSFG--TTSGGLFGNKPTL--TLGTNTNT 405 T GS TT+A + G TT+ G++ T T G+ T T Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTT 405 Score = 66.2 bits (160), Expect = 1e-10 Identities = 106/441 (24%), Positives = 173/441 (39%), Gaps = 54/441 (12%) Query: 18 GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72 G+ +T TG TT+ G+ S GS T G+ T ++ S+ Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394 Query: 73 TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 T ++TG T + T + T + G+ + + F + G+ T S+ T Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 T +T +T+ + G + TA TG+ TG +T + ++ +T + Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + E+ ++ E + +G +N TT GS T S TGL +++T+ G Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563 Query: 253 GQNKTAFGTSTT----GFGTNPGGLFGQQ-----------------NQQTTSLFSKPFGQ 291 T +TT G GT G + + +TTS + G Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTS--ASTTGS 621 Query: 292 ATTTQNTGFSFGNT-STIGQPSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGT 347 TTT +T S T ST G +T T G T T+T T T TG+ Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681 Query: 348 GLFGQT-NTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGT--TSGGLFGNKPTL--TLGTN 402 T +G V T K++T GS TT+ + G+ T+ + G++ T T G+ Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 403 TNTSNFGFGTNTSGNSIFGSK 423 T T++ G+ T+ S GS+ Sbjct: 742 TTTASTE-GSETTSASTTGSE 761 Score = 59.3 bits (142), Expect = 2e-08 Identities = 90/380 (23%), Positives = 152/380 (40%), Gaps = 53/380 (13%) Query: 71 PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122 PA ++T T + T L + T T+ S+ + PTG G+ T Sbjct: 9 PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182 +TS+ G TT +++ G+T+ S+ G S T + G+ TGT+T + + + + Sbjct: 67 TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124 Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242 +T S + E + + + VG+ TTT S T+++T Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173 Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302 +T + + + G+ TT T +TT++ + G TTT +T S Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223 Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359 ST+G +T T S G A+ ++ T TAF + + TGF Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283 Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG--TTSGGLFGNKPTL------------TLGTNT 403 ++ G+ +T GS TT A + G TT ++ T T+G+ T Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET 343 Query: 404 NTSNFGFGTNTSGNSIFGSK 423 T + G+ T+ SI GS+ Sbjct: 344 TTVS-TTGSETTTASIMGSE 362 Score = 43.1 bits (100), Expect = 0.001 Identities = 75/331 (22%), Positives = 112/331 (33%), Gaps = 71/331 (21%) Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188 G+ TT++ GS + ++ +S TA+ G+ PTG+ T + + + I+T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69 Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248 TA E + S G+GTTT S T S G S +TT Sbjct: 70 -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106 Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308 S TG T G + T+ S + T T G ST+ Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150 Query: 309 GQPSTNTMGLFGVTQASQPGG-----LFGTATNTSTGTAFGTGT---GLFGQTNTGFGAV 360 G +T T A+ G +F + T T + G+ T G T Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT 210 Query: 361 GSTLFG-------NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGF--- 410 GS +T GS TT + G+ + T T + +N F Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTED 270 Query: 411 ---------GTNTSGNSIFGSKPA-PGTLGT 431 G T+ S GS+P T+G+ Sbjct: 271 SKTTTASTTGFETTAASTTGSEPTMASTMGS 301 Score = 40.4 bits (93), Expect = 0.008 Identities = 67/267 (25%), Positives = 96/267 (35%), Gaps = 50/267 (18%) Query: 229 GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP 288 GS+ T+S TG S TT + TA ST G T G Q T++ S Sbjct: 12 GSNTTTASTTG---SETTTILIKASETTTA---STAGSETTTPSPTGSQ----TTIVSIS 61 Query: 289 FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348 + TTT G S+ G G T AS + G+ T ST + T Sbjct: 62 GSEITTTSTAGSENTTVSSAGS---------GTTTAS----MAGSETTVSTAGSETTTVS 108 Query: 349 LFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408 + G T A+GS T +STTS+ + T++ G T S Sbjct: 109 ITGTETTMVSAMGSE--------TTTNSTTSSETTVTSTAG----------SETTTVSTV 150 Query: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468 G T T+ + + T + G+ T AG ++ P G T A Sbjct: 151 GSETTTAYTA-----DSETTAASTTGSEMTTVFTAGSETI----TPSTAGSETTTVSTAG 201 Query: 469 GFNTTTATLGFGAPQAPVALTDPNASA 495 TT +T G A A ++ A++ Sbjct: 202 SETTTVSTTGSETTTASTAHSETTAAS 228 Score = 30.8 bits (68), Expect = 6.2 Identities = 31/123 (25%), Positives = 55/123 (44%), Gaps = 4/123 (3%) Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 ++ T P+ + T S+ + A+ T+T + G+ T T + V + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 364 LFGNNKLTTFGS--STTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFGFGTNTSGNSIF 420 +T GS +T S+ GTT+ + G++ T+ T G+ T T + GT T+ S Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI-TGTETTMVSAM 120 Query: 421 GSK 423 GS+ Sbjct: 121 GSE 123 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 79.3 bits (194), Expect = 2e-14 Identities = 122/491 (24%), Positives = 193/491 (39%), Gaps = 89/491 (18%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T+S + + + G+ T+AF S T GL +S T T + PA++T++G Sbjct: 986 TSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 1045 Query: 79 -----FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLF-- 130 +S+G+ +T ST F ++ F N T F ST+S G+ Sbjct: 1046 PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA 1105 Query: 131 --------GTTNTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181 G+ TT +P STS L G S +F P T +PP+ V+ + + Sbjct: 1106 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 1165 Query: 182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241 S T + S G + +F SSP S T Sbjct: 1166 RSPGSTPTTHFPASSTTS--------------------GHSEKSTIFHSSPDASGTTPSS 1205 Query: 242 SSSTTNSGFAYGQNKTAFG----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN 297 + STT+ ++ + G T+ G T PG ++ +T+ +S P TT Sbjct: 1206 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG-----LSEASTTFYSSPRSPTTTLSP 1260 Query: 298 TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357 + + +G+ ST T SQPG T + ST T GL ++ T Sbjct: 1261 ASMT---SLGVGEEST--------TSRSQPGSTHSTVSPAST-----TTPGLSEESTT-- 1302 Query: 358 GAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTS 415 V S+ G+ + T F STT++ + G +PT + +T+T+ F + TS Sbjct: 1303 --VYSSSRGSTETTVFPHSTTTS---------VHGEEPTTFHSRPASTHTTLFTEDSTTS 1351 Query: 416 G----NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFN 471 G ++ F PA + TGL A TA +++ F P G GT +P + Sbjct: 1352 GLTEESTAFPGSPA--STQTGLPATLTTADLGEESTTF----PSSSGSTGTKL--SPARS 1403 Query: 472 TTTATLGFGAP 482 TT+ +G P Sbjct: 1404 TTSGLVGESTP 1414 Score = 78.2 bits (191), Expect = 3e-14 Identities = 151/637 (23%), Positives = 236/637 (37%), Gaps = 102/637 (16%) Query: 19 TTSTFGQNTGFGT--TSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTS 76 +++T G++ T +S GA GT+ F + + T L G T P T + + P ++T+ Sbjct: 1625 SSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT 1684 Query: 77 TGFG-----FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKP-----TGFGNFGT---- 122 G F +S + +T AST TS S+ + + ++P T F T Sbjct: 1685 AGLSEKSTTFYSSPRSPDTTLSPAST-TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGV 1743 Query: 123 ---STSSGGLFGTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGT------- 170 ST+S G+T+TT +P GST+ S GP S F ++P T P T Sbjct: 1744 SQESTASHSSPGSTDTTLSP-GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA 1802 Query: 171 ------------DTMVKAGVST--NISTKHQCITAMKE------YESKSLEELRLEDYQA 210 T+ AG +T ST Q + K+ + + EL + + Sbjct: 1803 STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS 1862 Query: 211 NRKGPQNQVGAGTTT----------------GLFGSSPATSSATGLFSSST-------TN 247 P A +TT SPA S+ +GL ST + Sbjct: 1863 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 1922 Query: 248 SGFAYGQNKTAFG---------TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT---T 295 + ++ TA G +STT ++P ++ TS S P ATT Sbjct: 1923 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPD 1982 Query: 296 QNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNT 355 +T ST S + G + S L G +T + + T L G T T Sbjct: 1983 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 2042 Query: 356 GFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTS 415 + ST F ++ + +TT +P+ T+SG + + + +T+T+ F T T Sbjct: 2043 PGLSEKSTTFHSSPRS---PATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTP 2099 Query: 416 GNSIFG--SKPAPGTLGTGLGAGFGTALGAGQASLFGNNQP-KIGGPLGTGAFGAPGFNT 472 G S S +PG+ T L T G Q S ++ P L G+ A F Sbjct: 2100 GLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQ 2159 Query: 473 TTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEER 532 + T L + +++ ++S T SP R +S Sbjct: 2160 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP-------RTTLSPASSTSPG 2212 Query: 533 LKPTNPAAQKALTTPTHYKLTPR-PATRVRPKALQTT 568 L+ + A Q T P TP P+T P TT Sbjct: 2213 LQGESTAFQ---THPASTHTTPSPPSTATAPVEESTT 2246 Score = 77.0 bits (188), Expect = 8e-14 Identities = 121/491 (24%), Positives = 193/491 (39%), Gaps = 89/491 (18%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T+S + + + G+ T+AF S T GL +S T T + PA++T++G Sbjct: 2543 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 2602 Query: 79 FGFGTST-----GTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLF-- 130 ++T G+ +T ST F ++ F + T F ST+S G+ Sbjct: 2603 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 2662 Query: 131 --------GTTNTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181 G+ TT +P STS L G S +F P T +PP+ V+ + + Sbjct: 2663 STRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYH 2722 Query: 182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241 S T + S G + +F SSP S T Sbjct: 2723 RSPGSTPTTHFPASSTTS--------------------GHSEKSTIFHSSPDASGTTPSS 2762 Query: 242 SSSTTNSGFAYGQNKTAFG----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN 297 + STT+ ++ + G T+ G T PG ++ +T+ +S P TT Sbjct: 2763 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG-----LSEASTTFYSSPRSPTTTLSP 2817 Query: 298 TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357 + + +G+ ST T SQPG T + ST T GL ++ T Sbjct: 2818 ASMT---SLGVGEEST--------TSRSQPGSTHSTVSPAST-----TTPGLSEESTT-- 2859 Query: 358 GAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTS 415 V S+ G+ + T F STT++ + G +PT + +T+T+ F + TS Sbjct: 2860 --VYSSSPGSTETTVFPRSTTTS---------VRGEEPTTFHSRPASTHTTLFTEDSTTS 2908 Query: 416 G----NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFN 471 G ++ F PA + TGL A TA +++ F P G GT +P + Sbjct: 2909 GLTEESTAFPGSPA--STQTGLPATLTTADLGEESTTF----PSSSGSTGTTL--SPARS 2960 Query: 472 TTTATLGFGAP 482 TT+ +G P Sbjct: 2961 TTSGLVGESTP 2971 Score = 74.3 bits (181), Expect = 5e-13 Identities = 145/601 (24%), Positives = 227/601 (37%), Gaps = 89/601 (14%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T+S + + + G+ T+AF S T GL +S T T + PA++T++G Sbjct: 2069 TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 2128 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 ++T ++ ST T+L A + FG T+ S G+T+TT Sbjct: 2129 PSQESTTSHSS----PGSTDTALSPGSTTALS------FGQESTTFHSSP--GSTHTTLF 2176 Query: 139 PFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESK 198 P +TS + S+ + TG+ P + + G ST T H T Sbjct: 2177 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQT-HPASTHTTP-SPP 2234 Query: 199 SLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTA 258 S +E+ + P GS+P T F +S+T SG + + T Sbjct: 2235 STATAPVEESTTYHRSP-------------GSTPTTH-----FPASSTTSG--HSEKSTI 2274 Query: 259 FGTSTTGFGTNPGGLFGQ---QNQQTTSLFSKPFGQATT----TQNTGFSFGNTSTIGQP 311 F +S GT P + + TTS S + TT T G S +T+ P Sbjct: 2275 FHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP 2334 Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371 + T L + S G T + + G+ T T G +T++ ++ + Sbjct: 2335 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHST-VSPASTTTPGLSEESTTVYSSSPGS 2393 Query: 372 TFGSSTTSAPSFGTTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTSG----NSIFGSKPA 425 T TT P TTS + G +PT + +T+T+ F + TSG ++ F PA Sbjct: 2394 T---ETTVFPRTPTTS--VRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 2448 Query: 426 ------PGTLGTG-LG----------AGFGTALGAGQAS---LFGNNQPKIGGPLGTGAF 465 P TL T LG GT L +++ L G + P P T Sbjct: 2449 STQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETT 2508 Query: 466 GAPGFNTT-----TATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFR 520 PG TT +T + +P++P A P A+ V ++ +S ++S G + Sbjct: 2509 TLPGSPTTPSLSEKSTTFYTSPRSPDATLSP-ATTTSSGVSEE--SSTSHSQPGSTHTTA 2565 Query: 521 NPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLD 580 P S R T+ ++ + T L P T P TT SH G Sbjct: 2566 FPDSTTTPGLSRHSTTSHSSPGSTDT----TLLPASTTTSGPSQESTT----SHSSPGST 2617 Query: 581 D 581 D Sbjct: 2618 D 2618 Score = 72.8 bits (177), Expect = 1e-12 Identities = 149/625 (23%), Positives = 236/625 (37%), Gaps = 94/625 (15%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTS F + + S + T+ F +S+ T G S T T++ PA ST++G Sbjct: 1848 TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 1907 Query: 79 F-----GFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133 + +S G+ T+ S+ S S ++ TS SS TT Sbjct: 1908 LVEESTAYHSSPGSTQTMHFPESSTASGRSEESR--------------TSHSS-----TT 1948 Query: 134 NTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC----- 188 +T S+P +TS + P+S+ ++P T P D+ +G S + H Sbjct: 1949 HTISSPPSTTSALVEEPTSYHSSPGSTATTHFP----DSSTTSGRSEESTASHSSQDATG 2004 Query: 189 --ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGL------FGSSPATSSATGL 240 + + S L E + G+ TT GL F SSP S AT L Sbjct: 2005 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR-SPATTL 2063 Query: 241 FSSSTTNSGFAY----------GQNKTAFGTSTTGFGTNPGGLFGQQNQQTT-------- 282 +STT+SG + + TAF STT G + + +T Sbjct: 2064 SPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 2123 Query: 283 SLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFG---VTQASQPGG----LFGTAT 335 + S P ++TT+ + S G+T T P + T FG T S PG LF +T Sbjct: 2124 TTTSGPSQESTTSHS---SPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 2180 Query: 336 NTS----TGTAFGTGTGLFGQTNTGFGAVGSTLFG-NNKLTTFGSSTTSAPSFGTTSGGL 390 +S T + TG T + + L G + T +ST + PS +T+ Sbjct: 2181 TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 2240 Query: 391 FGNKPTLTLGT-NTNTSNFGFGTNTSGNS----IFGSKPAPGTLGTGLGAGFGTALGAGQ 445 T +T T++F + TSG+S IF S +P GT + T G G+ Sbjct: 2241 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS--SPDASGTTPSSAHSTTSGRGE 2298 Query: 446 ASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHI 505 ++ + G+ PG + + T + +P++P P AS V ++ Sbjct: 2299 STTSRISPGSTEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSP-ASMTSLGVGEEST 2356 Query: 506 NSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATR------ 559 S + S + + P EE T ++ T T + TP + R Sbjct: 2357 TSRSQPGSTHSTVSPASTTTPGLSEE--STTVYSSSPGSTETTVFPRTPTTSVRGEEPTT 2414 Query: 560 --VRPKALQTTGTAKSHLFDGLDDD 582 RP + TT + GL ++ Sbjct: 2415 FHSRPASTHTTLFTEDSTTSGLTEE 2439 Score = 71.2 bits (173), Expect = 4e-12 Identities = 127/528 (24%), Positives = 198/528 (37%), Gaps = 65/528 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTS F + + S + T+ + + T GL S T T + P + T++G Sbjct: 793 TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 852 Query: 79 FGFGTST---GTANTLFGTAST-------GTSLFSSQNNAFAQNKP---TGFGNFGTSTS 125 G ++T T +T+ ST TS SS + + P T G ST+ Sbjct: 853 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 912 Query: 126 SGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185 S T T P ST+ L G S+ + +G+ P T T G+S +T Sbjct: 913 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT---PGLSERSTTF 969 Query: 186 HQC----ITAMKEYESKSLEELRLEDYQANRKGPQNQVG---AGTTTGLFGSSPATSSAT 238 H T + + S +R G + + TT GL S + S+ Sbjct: 970 HSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 1029 Query: 239 G-----LFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQ-NQQTTSLFSKPFGQA 292 G L +STT SG + + + +T +PG Q++T+ S P Sbjct: 1030 GSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTH 1089 Query: 293 TT-----TQNTGFSFGNT----------STIGQPSTNTMGLFGVTQASQ--PGGLFGTAT 335 TT T ++G +T +T+ S+ + GL G + A Q P T + Sbjct: 1090 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 1149 Query: 336 NTSTGTAFGTGTGLF----GQTNTGFGAVGSTLFGNNKLTTF------GSSTTSAPSFGT 385 ST TA + + G T T ST G+++ +T S TT + + T Sbjct: 1150 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 1209 Query: 386 TSGGLFGNKPTLTLGTNTNTSNFGFGTN---TSGNSIFGSKPAPGTLGTGLGAGFGTALG 442 TSG ++ G+ T+ G T + ++ F S P T T L T+LG Sbjct: 1210 TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT--TTLSPASMTSLG 1267 Query: 443 AGQASLFGNNQP----KIGGPLGTGAFGAPGFNTTTATLGFGAPQAPV 486 G+ S +QP P T G +TT + G+ + V Sbjct: 1268 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV 1315 Score = 69.7 bits (169), Expect = 1e-11 Identities = 136/573 (23%), Positives = 214/573 (37%), Gaps = 112/573 (19%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TT+ G+ + +S G+ GT+ + + T GL G S T + + P + T+ Sbjct: 2933 TTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS 2992 Query: 79 FG-----FGTSTGTANTLFGTASTGTSLFSSQNN-AFAQNKPTGFGNFGTSTSSGGLF-- 130 F TS + + A+T +S S +++ + +Q T F ST++ GL Sbjct: 2993 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQE 3052 Query: 131 --------GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNP-PTGTDTMVKAGVS 179 G+T T +P GST+ S G S F ++P T P T T +V+A Sbjct: 3053 PTASHSSQGSTEATLSP-GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTP 3111 Query: 180 TNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG 239 T+ ST G+ TT +PA+S++ G Sbjct: 3112 THSST-----------------------------------GSLHTT----LTPASSTSAG 3132 Query: 240 LFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTG 299 L STT + + T +P G + +T+ S+P ++T T Sbjct: 3133 LQEESTTFQSWPSSSDTT----------PSPPGTTAAPVEVSTTYHSRP----SSTPTTH 3178 Query: 300 FSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGA 359 FS +T T+G+ +T T S PG AT T+ + L G+ T + Sbjct: 3179 FSASST-TLGRSEEST------TVHSSPG-----ATGTALFPTRSATSVLVGEPTTSPIS 3226 Query: 360 VGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSI 419 GST GS+TT+ S +T+ P TL + TS+ +T+ +S Sbjct: 3227 SGST----ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS- 3281 Query: 420 FGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQP-KIGGPLGTGAFGAPGFNTTTATLG 478 PG+ T G T G Q S ++ P L G+ A + T Sbjct: 3282 -----RPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH 3336 Query: 479 FGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPF------------GDSPLFRNPMSDP 526 G L N +A+ ++S T SP G+S F+ S P Sbjct: 3337 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ---SWP 3393 Query: 527 KKKEER-LKPTNPAAQKALTTPTHYKLTPRPAT 558 K+ PT +A L+T +H + P T Sbjct: 3394 NSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT 3426 Score = 69.3 bits (168), Expect = 2e-11 Identities = 147/630 (23%), Positives = 230/630 (36%), Gaps = 104/630 (16%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTS F + + S + T+ F +S+ T G S T T++ PA ST++G Sbjct: 3405 TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 3464 Query: 79 F-----GFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133 + +S G+ T+ S TS G G T++ S TT Sbjct: 3465 LVEESTTYHSSPGSTQTMHFPESDTTS---------------GRGEESTTSHSS----TT 3505 Query: 134 NTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC----- 188 +T S+ +TS + P+S+ ++P T P D+ +G S + H Sbjct: 3506 HTISSAPSTTSALVEEPTSYHSSPGSTATTHFP----DSSTTSGRSEESTASHSSQDATG 3561 Query: 189 --ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGL------FGSSPATSSATGL 240 + + S L E + G+ TT GL F SSP S AT L Sbjct: 3562 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR-SPATTL 3620 Query: 241 FSSSTTNSGFAY----------GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFG 290 +STT+SG + + TAF STT G + + +T P Sbjct: 3621 SPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLP-- 3678 Query: 291 QATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLF 350 A+TT + TS ST+T G T A FG + T + T T LF Sbjct: 3679 -ASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALS----FGQESTTFHSSPGSTHTTLF 3733 Query: 351 GQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGL------FGNKPTLTLGT--- 401 + T G V ++ ++ GS T+ +TS GL F P T T Sbjct: 3734 PDSTTSSGIVEAS---TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP 3790 Query: 402 -------------------NTNTSNFGFGTNTSGNS----IFGSKPAPGTLGTGLGAGFG 438 +T T++F + TSG+S IF S +P GT + Sbjct: 3791 PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS--SPDASGTTPSSAHS 3848 Query: 439 TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 498 T G G+++ + G+ PG + + T + +P++P P AS Sbjct: 3849 TTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSP-ASMTSL 3906 Query: 499 AVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEE--RLKPTNPAAQKALTTPTHYKLTPR- 555 V ++ S + S + + P EE + ++P + + P + R Sbjct: 3907 GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRR 3966 Query: 556 --PAT-RVRPKALQTTGTAKSHLFDGLDDD 582 P T RP + TT + GL ++ Sbjct: 3967 EEPTTFHSRPASTHTTLFTEDSTTSGLTEE 3996 Score = 68.6 bits (166), Expect = 3e-11 Identities = 142/613 (23%), Positives = 228/613 (37%), Gaps = 77/613 (12%) Query: 31 TTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG---TSTGT 87 TT A T+ G S + T+P TS+F +P+T TS G T Sbjct: 760 TTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST-TSHGSPSSIPTTHISA 818 Query: 88 ANTLFGTASTGTSLFSSQNNAFAQNKP-----TGFGNFGTSTSSGGLFGTTNTTSNPFGS 142 +T G T+ SS + + P +G G T++ S TT+T S+ + Sbjct: 819 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS----STTHTISSAPST 874 Query: 143 TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQ-------CITAMKEY 195 TS + P+S+ ++P T P D+ +G S + H + + Sbjct: 875 TSALVEEPTSYHSSPGSTATTHFP----DSSTTSGRSEESTASHSSQDATGTIVLPARST 930 Query: 196 ESKSLEELRLEDYQANRKGPQNQVGAGTTTGL------FGS---------SPATSSATGL 240 S L E + G+ TT GL F S SPA+++++G+ Sbjct: 931 TSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGV 990 Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTT--------SLFSKPFGQA 292 STT+ + TAF STT G + + +T + S P ++ Sbjct: 991 SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQES 1050 Query: 293 TTTQNTGFSFGNTSTIGQPSTNTMGLFG---VTQASQPGG----LFGTATNTS----TGT 341 TT+ + S G+T T P + T FG T S PG LF +T +S T Sbjct: 1051 TTSHS---SSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAST 1107 Query: 342 AFGTGTGLFGQTNTGFGAVGSTLFG-NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLG 400 + TG T + + L G + T +ST + PS +T+ T Sbjct: 1108 RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 1167 Query: 401 T-NTNTSNFGFGTNTSGNS----IFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPK 455 +T T++F + TSG+S IF S +P GT + T G G+++ + Sbjct: 1168 PGSTPTTHFPASSTTSGHSEKSTIFHS--SPDASGTTPSSAHSTTSGRGESTTSRISPGS 1225 Query: 456 IGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGD 515 G+ PG + + T + +P++P P AS V ++ S + Sbjct: 1226 TEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSP-ASMTSLGVGEESTTSRSQPGSTH 1283 Query: 516 SPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLT-----PRPAT-RVRPKALQTTG 569 S + + P EE + + TT + T P T RP + TT Sbjct: 1284 STVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTL 1343 Query: 570 TAKSHLFDGLDDD 582 + GL ++ Sbjct: 1344 FTEDSTTSGLTEE 1356 Score = 67.8 bits (164), Expect = 5e-11 Identities = 179/779 (22%), Positives = 276/779 (35%), Gaps = 127/779 (16%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T+S + + + G+ T+AF S T GL T T + P ++T++ Sbjct: 4100 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASS 4159 Query: 79 FG-----FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133 G F +S G T T TS G ST + G+ Sbjct: 4160 LGQQSTTFHSSPGDTETTLLPDDTITS-----------------GLVEASTPTHSSTGSL 4202 Query: 134 NTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 +TT P STS L S +F + P+ + +PP + T V VST ++ T Sbjct: 4203 HTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPP--STTAVPVEVSTTYHSRPSS-TPT 4259 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252 + + S R E+ P T T LF + ATS G ++S +SG Sbjct: 4260 THFSASSTTLGRSEESTTVHSSP-----GATGTALFPTRSATSVLVGEPTTSPISSG--- 4311 Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312 TA STT G ++++T+ +S P TT S +T++ G Sbjct: 4312 STETTALPGSTTTAGL---------SEKSTTFYSSPRSPDTT-----LSPASTTSSGVSE 4357 Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372 +T T S+PG + TA +ST T G+ ++ + GST TT Sbjct: 4358 EST------TSHSRPGSMHTTAFPSST-----TMPGVSQESTASHSSPGST------DTT 4400 Query: 373 FGSSTTSAPSFG---TTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGS-----KP 424 +T+A S G TT G+ T L NT S +T +S GS P Sbjct: 4401 LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL-LEASTPVHSSTGSPHTTLSP 4459 Query: 425 APGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPG------FNTTTATLG 478 A T G F + + + L T + G+P F+ ++ TLG Sbjct: 4460 AGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG 4519 Query: 479 FG-----APQAPVA-LTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEER 532 +PVA T P+ + + + L + + SP G + P S+ Sbjct: 4520 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSP-GSTQTMHFPESNTTSGRGE 4578 Query: 533 LKPTN-----------PAAQKALT-TPTHYKLTP-RPATRVRPKALQTTGTAKSHLFDGL 579 T+ P+ AL PT Y +P AT P + T+G ++ Sbjct: 4579 ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 4638 Query: 580 DDDEPSLANGAF-MPKKSIKKLVLKNLNNSNLFS--------PVNRDSENL--------A 622 D A G +P +S ++L S + S P + + L + Sbjct: 4639 SQD----ATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS 4694 Query: 623 SPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT-NPIAKPIPQTPESAGNKHSNS 681 SPS P FS S + + + S V+ T +P E + HS+ Sbjct: 4695 SPSSTPTT--HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSP 4752 Query: 682 NSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEI---ENNSYHMHPAGIILT 737 S + A+ R+ +S ++ H S E SYH P I T Sbjct: 4753 GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATT 4811 Score = 66.2 bits (160), Expect = 1e-10 Identities = 128/558 (22%), Positives = 214/558 (38%), Gaps = 82/558 (14%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TT+ G+ + +S G+ GT + + T GL G S S S +T T+T Sbjct: 1376 TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGEST--------PSRLSPSSTETTTL 1427 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 G T+ + T+ ++S + A P +T+S G+ ++T+ + Sbjct: 1428 PGSPTTP-------SLSEKSTTFYTSPRSPDATLSP-------ATTTSSGVSEESSTSHS 1473 Query: 139 PFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESK 198 GST + F S+ T+ + + G+ + ST S+ Q T Sbjct: 1474 QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1533 Query: 199 SLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG-----LFSSSTTNSGFAYG 253 + L +D T+GL +S T S+TG L +S+T++G Sbjct: 1534 TETTLLPDD--------------TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEE 1579 Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313 S++ +P G + +T+ S+P ++T T FS +T T+G+ Sbjct: 1580 STTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRP----SSTPTTHFSASST-TLGRSEE 1634 Query: 314 NTMGLFGVTQASQPG----GLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFG--N 367 +T T S PG LF T + TS T + + + GST + Sbjct: 1635 ST------TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS 1688 Query: 368 NKLTTFGSS-----TTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNS--IF 420 K TTF SS TT +P+ T+SG + + + +T+T+ F T G S Sbjct: 1689 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 1748 Query: 421 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480 S +PG+ T L G TA G S ++ P G+ NTT + L Sbjct: 1749 ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSP------GSTETTLLPDNTTASGLLEA 1802 Query: 481 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 540 + + P+ + + + S T+ + P ++ M P PT +A Sbjct: 1803 STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW---PSSKDTMPAP--------PTTTSA 1851 Query: 541 QKALTTPTHYKLTPRPAT 558 L+T +H + P T Sbjct: 1852 FVELSTTSHGSPSSTPTT 1869 Score = 65.1 bits (157), Expect = 3e-10 Identities = 129/518 (24%), Positives = 204/518 (39%), Gaps = 66/518 (12%) Query: 28 GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84 G TT G + ++ F SS + T L S T G G T+S SQP ++ ST T+ Sbjct: 3873 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 3932 Query: 85 TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137 T + T++ ++ ST T++F S + + +PT F + ST + LF +TTS Sbjct: 3933 TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTT-LFTEDSTTS 3991 Query: 138 NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 G T S P S + TG TT + T T +S + + Sbjct: 3992 ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244 + S + P + +T + S SPAT++++G+ S Sbjct: 4049 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 4108 Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP-------FGQATTTQN 297 +T+ + TAF STT G + +Q +T P GQ +TT + Sbjct: 4109 STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 4168 Query: 298 TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357 + S G+T T P G+ +AS P T++STG+ T T T+TG Sbjct: 4169 S--SPGDTETTLLPDDTITS--GLVEASTP-------THSSTGSLHTTLTPA-SSTSTGL 4216 Query: 358 GAVGSTLF---GNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNT 414 +T ++ T STT+ P +T+ + ++P+ T T+ + S+ G + Sbjct: 4217 QEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTT---YHSRPSSTPTTHFSASSTTLGRSE 4273 Query: 415 SGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTT 474 ++ S PG GT L F T P G T A PG TT Sbjct: 4274 ESTTVHSS---PGATGTAL---FPTRSATSVLVGEPTTSPISSGSTETTAL--PGSTTTA 4325 Query: 475 -----ATLGFGAPQAPVALTDPNASAAQQAVLQQHINS 507 +T + +P++P P AS V ++ S Sbjct: 4326 GLSEKSTTFYSSPRSPDTTLSP-ASTTSSGVSEESTTS 4362 Score = 62.0 bits (149), Expect = 3e-09 Identities = 170/776 (21%), Positives = 276/776 (35%), Gaps = 134/776 (17%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T S + + + GA GT+ F S + T G +T P + + P ++T+ G Sbjct: 216 TNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAG 275 Query: 79 FG------FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPT---GFGNFGT------- 122 + + TL +T + + + ++ PT F + T Sbjct: 276 LSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQE 335 Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSS--FTAAPTGT-TIKFNPPTGTDTMVKAGVS 179 ST+S + G+T+TT +P G+T+ S GP S F ++P T T + T T +++A Sbjct: 336 STASHSIPGSTDTTLSP-GTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTP 394 Query: 180 TNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG 239 + ST T S + E +Q+ P ++ +SPA S T Sbjct: 395 VHSSTGSPHTTLSP--SSSTTHEGEPTTFQS---WPSSK----------DTSPAPSGTTS 439 Query: 240 LF-SSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT---- 294 F STT T F S+T G ++++T + S P ATT Sbjct: 440 AFVKLSTTYHSSPSSTPTTHFSASSTTLG---------HSEESTPVHSSPVATATTPPPA 490 Query: 295 --------TQNTGF--SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344 ++T + S G+T T+ P ++T A+ G T ++T + TA Sbjct: 491 RSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAAL 550 Query: 345 TGTGL---FGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGT 401 T G T T ST+ G ++ + ++ S+P T+ G+ P++ +G Sbjct: 551 AHTSYHSSLGSTETTHFRDSSTISGRSEES---KASHSSPDAMATTVLPAGSTPSVLVGD 607 Query: 402 NTNT--------------SNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQAS 447 +T + S G + + + S +P T T L A T+ G + S Sbjct: 608 STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDT--THLPASM-TSSGVSEES 664 Query: 448 LFGNNQPKIGGPLGTGAFGAPGFNT-----TTATLGFGAPQAPVALTDPNASAAQQAVLQ 502 +++P G T AF PG T +T +P P ++ A Sbjct: 665 TTSHSRP---GSTHTTAF--PGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSL--- 716 Query: 503 QHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKAL--TTPTHYKLTPRPATRV 560 P + S P E L P N A L + P H T P T + Sbjct: 717 -------------GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVH-SSTRSPHTTL 762 Query: 561 RPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSEN 620 P A TT +S F PS + P + V + + S + Sbjct: 763 SP-AGSTTRQGESTTFHSW----PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSI------ 811 Query: 621 LASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSN 680 P+ + S L + H G ++ HF P + E + HS+ Sbjct: 812 ---PTTHISARSTTSGLVEESTTYHSSPGSTQTM--HF---PESDTTSGRGEESTTSHSS 863 Query: 681 S----NSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPA 732 + +S T AL + GS+ T F D S R E S+ A Sbjct: 864 TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 919 Score = 62.0 bits (149), Expect = 3e-09 Identities = 128/518 (24%), Positives = 202/518 (38%), Gaps = 66/518 (12%) Query: 28 GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84 G TT G + ++ F SS + T L S T G G T+S SQP ++ ST T+ Sbjct: 2790 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2849 Query: 85 TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137 T + T++ ++ ST T++F S + +PT F + ST + LF +TTS Sbjct: 2850 TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTT-LFTEDSTTS 2908 Query: 138 NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 G T S P S + TG TT + T T +S + + Sbjct: 2909 ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2965 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244 + S + P + +T + S SPAT++++G+ S Sbjct: 2966 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 3025 Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP-------FGQATTTQN 297 +T+ + TAF STT G + +Q +T P GQ +TT + Sbjct: 3026 STSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFH 3085 Query: 298 TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357 + S G+T T P G+ +AS P T++STG+ T T T+ G Sbjct: 3086 S--SPGDTETTLLPDDTITS--GLVEASTP-------THSSTGSLHTTLTPA-SSTSAGL 3133 Query: 358 GAVGSTLF---GNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNT 414 +T ++ T TT+AP +T+ + ++P+ T T+ + S+ G + Sbjct: 3134 QEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTT---YHSRPSSTPTTHFSASSTTLGRSE 3190 Query: 415 SGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTT 474 ++ S PG GT L F T P G T A PG TT Sbjct: 3191 ESTTVHSS---PGATGTAL---FPTRSATSVLVGEPTTSPISSGSTETTAL--PGSTTTA 3242 Query: 475 -----ATLGFGAPQAPVALTDPNASAAQQAVLQQHINS 507 +T + +P++P P AS V ++ S Sbjct: 3243 GLSEKSTTFYSSPRSPDTTLSP-ASTTSSGVSEESTTS 3279 Score = 59.7 bits (143), Expect = 1e-08 Identities = 181/794 (22%), Positives = 286/794 (36%), Gaps = 113/794 (14%) Query: 28 GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84 G TT G + ++ F SS + T L S T G G T+S SQP ++ ST T+ Sbjct: 1233 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 1292 Query: 85 TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137 T + T++ ++ ST T++F S + +PT F + ST + LF +TTS Sbjct: 1293 TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT-LFTEDSTTS 1351 Query: 138 NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 G T S P S + TG TT + T T +S + + Sbjct: 1352 ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 1408 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244 + S + P + +T + S SPAT++++G+ S Sbjct: 1409 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 1468 Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP-------FGQATTTQN 297 +T+ + TAF STT + +Q +T P GQ +TT + Sbjct: 1469 STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 1528 Query: 298 TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLF------- 350 + S G+T T P G+ +AS P + +T+ A T GL Sbjct: 1529 S--SPGDTETTLLPDDTITS--GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 1584 Query: 351 ---GQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPS--FGTTSGGLFGNKPTLTLGTNTNT 405 ++T G+T TT+ S +S P+ F +S L ++ + T+ ++ Sbjct: 1585 SWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGA 1644 Query: 406 SNFGFGTNTSGNSIFGSKPAPGTLGTGLG-----AGFGTALGAGQASLFGNNQPKIG--- 457 + S S+ +P + +G G T G + S + P+ Sbjct: 1645 TGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTT 1704 Query: 458 -GPLGTGAFGAPGFNTT-------TATLGF-GAPQAPVALTDPNASAAQQAVLQQHIN-- 506 P T + G +TT T T F G+ P + AS + ++ Sbjct: 1705 LSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPG 1764 Query: 507 SLTYSPFG-DSPLFRNPMSDPKKKEERLKPTNPAAQKAL--TTPTHYKLTPRPATRVRPK 563 S T S G +S F S P E L P N A L +TP H T P T + P Sbjct: 1765 STTASSLGPESTTFH---SSPGSTETTLLPDNTTASGLLEASTPVH-SSTGSPHTTLSP- 1819 Query: 564 ALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSENL-A 622 A TT +S F + + MP L+ ++ SP + + + A Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDT------MPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA 1873 Query: 623 SPSEYPENGERFSFLSKP-----------------VDEN---HQQDGDEDSLVSHFYTNP 662 S + + E + S P V+E+ H G ++ HF P Sbjct: 1874 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTM--HF---P 1928 Query: 663 IAKPIPQTPESAGNKHSNS----NSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDD 718 + E + HS++ +S T AL + GS+ T F D S Sbjct: 1929 ESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG 1988 Query: 719 REEIENNSYHMHPA 732 R E S+ A Sbjct: 1989 RSEESTASHSSQDA 2002 Score = 59.7 bits (143), Expect = 1e-08 Identities = 143/609 (23%), Positives = 235/609 (38%), Gaps = 65/609 (10%) Query: 28 GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84 G TT G + ++ F SS + T L S T G G T+S SQP ++ ST T+ Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2375 Query: 85 TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137 T + T++ ++ ST T++F + + +PT F + ST + LF +TTS Sbjct: 2376 TPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTT-LFTEDSTTS 2434 Query: 138 NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 G T S P S + TG TT + T T +S + + Sbjct: 2435 ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2491 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244 + S + P + +T + S SPAT++++G+ S Sbjct: 2492 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 2551 Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTT--------SLFSKPFGQATTTQ 296 +T+ + TAF STT G + + +T + S P ++TT+ Sbjct: 2552 STSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 2611 Query: 297 NTGFSFGNTSTIGQPSTNTMGLFG---VTQASQPGG----LFGTATNTS----TGTAFGT 345 + S G+T T P + T FG T S PG LF +T +S T + Sbjct: 2612 S---SPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHS 2668 Query: 346 GTGLFGQTNTGFGAVGSTLFG-NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGT-NT 403 TG T + + L G + T +ST + PS +T+ T +T Sbjct: 2669 STGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 2728 Query: 404 NTSNFGFGTNTSGNS----IFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP 459 T++F + TSG+S IF S +P GT + T G G+++ + Sbjct: 2729 PTTHFPASSTTSGHSEKSTIFHS--SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT 2786 Query: 460 LGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLF 519 G+ PG + + T + +P++P P AS V ++ S + S + Sbjct: 2787 TLPGSTTTPGLSEASTTF-YSSPRSPTTTLSP-ASMTSLGVGEESTTSRSQPGSTHSTVS 2844 Query: 520 RNPMSDPKKKEE--RLKPTNPAAQKALTTPTHYKLTPR---PAT-RVRPKALQTTGTAKS 573 + P EE + ++P + + P + R P T RP + TT + Sbjct: 2845 PASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTED 2904 Query: 574 HLFDGLDDD 582 GL ++ Sbjct: 2905 STTSGLTEE 2913 Score = 58.9 bits (141), Expect = 2e-08 Identities = 105/444 (23%), Positives = 166/444 (37%), Gaps = 68/444 (15%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTS + S G+ T+A S T GL S T T + A+ST+ G Sbjct: 4653 TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLG 4712 Query: 79 FGFGTST------GTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLF-- 130 ++T TA T ST + L + T +F S+++ G Sbjct: 4713 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE 4772 Query: 131 ------GTTNTTSNPFGSTSGSLFGPSSFTAAPTG-TTIKFNPPTGTDTMVKAGVSTNIS 183 TT+T S+P +TS + P+S+ ++P T F + T + +++ S Sbjct: 4773 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS 4832 Query: 184 TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGA-GTTTGLFGS------------ 230 IT + + + S + + + + + TT GL Sbjct: 4833 PDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPD 4892 Query: 231 ---SPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSK 287 SPA+ +++ + T+ A + TAF STT G +Q++T+ SK Sbjct: 4893 QTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGL---------SQESTTFHSK 4943 Query: 288 PFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT 347 P G TT + G TS+ Q T T SQPG T + ST T Sbjct: 4944 P-GSTETTLSPGSI--TTSSFAQEFT--------TPHSQPGSALSTVSPAST-----TVP 4987 Query: 348 GLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLT---LGTNTN 404 GL ++ T + + GST + T F S T S + F + P T L Sbjct: 4988 GLSEESTTFYSSPGST-----ETTAFSHSNTM--SIHSQQSTPFPDSPGFTHTVLPATLT 5040 Query: 405 TSNFGFGTNT--SGNSIFGSKPAP 426 T++ G + S + G+ P P Sbjct: 5041 TTDIGQESTAFHSSSDATGTTPLP 5064 Score = 32.7 bits (73), Expect = 1.6 Identities = 53/195 (27%), Positives = 77/195 (39%), Gaps = 25/195 (12%) Query: 235 SSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT 294 S+AT F S+TNSG + + G TG P + TS+F G+ T Sbjct: 205 STATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFP-------SHSATSVF---VGEPKT 254 Query: 295 TQNTGFSFGNTSTIGQPSTNTMGLFG-----VTQASQPGGLFGTATNTSTGTAFGTGTGL 349 + T S T+ G ST T GL + P A TS+G + + T Sbjct: 255 SPITSASMETTALPG--STTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSH 312 Query: 350 F--GQTNTGFGAVGSTLFGNNKLTT----FGSSTTSAPSFGTTSGGLFGNKPTLTLGT-- 401 G T+T +T+ G ++ +T ST + S GTT+ G + T + Sbjct: 313 SRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPG 372 Query: 402 NTNTSNFGFGTNTSG 416 T T+ T TSG Sbjct: 373 YTKTTRLPDNTTTSG 387 Score = 31.2 bits (69), Expect = 4.7 Identities = 55/237 (23%), Positives = 86/237 (36%), Gaps = 24/237 (10%) Query: 31 TTSG-GAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTSTGFGFGTSTG- 86 TT G A T + SS + + + G TS +SQ ++ +T F T+T Sbjct: 4873 TTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSG 4932 Query: 87 ------TANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT--------STSSGGLFGT 132 T ++ G+ T S S ++FAQ T G+ ST+ GL Sbjct: 4933 LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 4992 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 + T + GST + F S+ + + + F G V T + Sbjct: 4993 STTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFH 5052 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQV---GAGTTTGLFGSSPATSSATGLFSSSTT 246 ++ L ++ G + T T LF PA+SS +GL STT Sbjct: 5053 SSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLF---PASSSTSGLTEESTT 5106 >gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo sapiens] Length = 2036 Score = 79.3 bits (194), Expect = 2e-14 Identities = 122/491 (24%), Positives = 193/491 (39%), Gaps = 89/491 (18%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T+S + + + G+ T+AF S T GL +S T T + PA++T++G Sbjct: 473 TSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 532 Query: 79 -----FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLF-- 130 +S+G+ +T ST F ++ F N T F ST+S G+ Sbjct: 533 PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA 592 Query: 131 --------GTTNTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181 G+ TT +P STS L G S +F P T +PP+ V+ + + Sbjct: 593 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 652 Query: 182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241 S T + S G + +F SSP S T Sbjct: 653 RSPGSTPTTHFPASSTTS--------------------GHSEKSTIFHSSPDASGTTPSS 692 Query: 242 SSSTTNSGFAYGQNKTAFG----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN 297 + STT+ ++ + G T+ G T PG ++ +T+ +S P TT Sbjct: 693 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG-----LSEASTTFYSSPRSPTTTLSP 747 Query: 298 TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357 + + +G+ ST T SQPG T + ST T GL ++ T Sbjct: 748 ASMT---SLGVGEEST--------TSRSQPGSTHSTVSPAST-----TTPGLSEESTT-- 789 Query: 358 GAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTL--TLGTNTNTSNFGFGTNTS 415 V S+ G+ + T F STT++ + G +PT + +T+T+ F + TS Sbjct: 790 --VYSSSRGSTETTVFPHSTTTS---------VHGEEPTTFHSRPASTHTTLFTEDSTTS 838 Query: 416 G----NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFN 471 G ++ F PA + TGL A TA +++ F P G GT +P + Sbjct: 839 GLTEESTAFPGSPA--STQTGLPATLTTADLGEESTTF----PSSSGSTGTKL--SPARS 890 Query: 472 TTTATLGFGAP 482 TT+ +G P Sbjct: 891 TTSGLVGESTP 901 Score = 71.2 bits (173), Expect = 4e-12 Identities = 127/528 (24%), Positives = 198/528 (37%), Gaps = 65/528 (12%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTS F + + S + T+ + + T GL S T T + P + T++G Sbjct: 280 TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 339 Query: 79 FGFGTST---GTANTLFGTAST-------GTSLFSSQNNAFAQNKP---TGFGNFGTSTS 125 G ++T T +T+ ST TS SS + + P T G ST+ Sbjct: 340 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 399 Query: 126 SGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185 S T T P ST+ L G S+ + +G+ P T T G+S +T Sbjct: 400 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT---PGLSERSTTF 456 Query: 186 HQC----ITAMKEYESKSLEELRLEDYQANRKGPQNQVG---AGTTTGLFGSSPATSSAT 238 H T + + S +R G + + TT GL S + S+ Sbjct: 457 HSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 516 Query: 239 G-----LFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQ-NQQTTSLFSKPFGQA 292 G L +STT SG + + + +T +PG Q++T+ S P Sbjct: 517 GSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTH 576 Query: 293 TT-----TQNTGFSFGNT----------STIGQPSTNTMGLFGVTQASQ--PGGLFGTAT 335 TT T ++G +T +T+ S+ + GL G + A Q P T + Sbjct: 577 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 636 Query: 336 NTSTGTAFGTGTGLF----GQTNTGFGAVGSTLFGNNKLTTF------GSSTTSAPSFGT 385 ST TA + + G T T ST G+++ +T S TT + + T Sbjct: 637 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 696 Query: 386 TSGGLFGNKPTLTLGTNTNTSNFGFGTN---TSGNSIFGSKPAPGTLGTGLGAGFGTALG 442 TSG ++ G+ T+ G T + ++ F S P T T L T+LG Sbjct: 697 TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT--TTLSPASMTSLG 754 Query: 443 AGQASLFGNNQP----KIGGPLGTGAFGAPGFNTTTATLGFGAPQAPV 486 G+ S +QP P T G +TT + G+ + V Sbjct: 755 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTV 802 Score = 68.6 bits (166), Expect = 3e-11 Identities = 142/613 (23%), Positives = 228/613 (37%), Gaps = 77/613 (12%) Query: 31 TTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFG---TSTGT 87 TT A T+ G S + T+P TS+F +P+T TS G T Sbjct: 247 TTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST-TSHGSPSSIPTTHISA 305 Query: 88 ANTLFGTASTGTSLFSSQNNAFAQNKP-----TGFGNFGTSTSSGGLFGTTNTTSNPFGS 142 +T G T+ SS + + P +G G T++ S TT+T S+ + Sbjct: 306 RSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS----STTHTISSAPST 361 Query: 143 TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQ-------CITAMKEY 195 TS + P+S+ ++P T P D+ +G S + H + + Sbjct: 362 TSALVEEPTSYHSSPGSTATTHFP----DSSTTSGRSEESTASHSSQDATGTIVLPARST 417 Query: 196 ESKSLEELRLEDYQANRKGPQNQVGAGTTTGL------FGS---------SPATSSATGL 240 S L E + G+ TT GL F S SPA+++++G+ Sbjct: 418 TSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGV 477 Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTT--------SLFSKPFGQA 292 STT+ + TAF STT G + + +T + S P ++ Sbjct: 478 SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQES 537 Query: 293 TTTQNTGFSFGNTSTIGQPSTNTMGLFG---VTQASQPGG----LFGTATNTS----TGT 341 TT+ + S G+T T P + T FG T S PG LF +T +S T Sbjct: 538 TTSHS---SSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAST 594 Query: 342 AFGTGTGLFGQTNTGFGAVGSTLFG-NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLG 400 + TG T + + L G + T +ST + PS +T+ T Sbjct: 595 RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 654 Query: 401 T-NTNTSNFGFGTNTSGNS----IFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPK 455 +T T++F + TSG+S IF S +P GT + T G G+++ + Sbjct: 655 PGSTPTTHFPASSTTSGHSEKSTIFHS--SPDASGTTPSSAHSTTSGRGESTTSRISPGS 712 Query: 456 IGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGD 515 G+ PG + + T + +P++P P AS V ++ S + Sbjct: 713 TEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSP-ASMTSLGVGEESTTSRSQPGSTH 770 Query: 516 SPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLT-----PRPAT-RVRPKALQTTG 569 S + + P EE + + TT + T P T RP + TT Sbjct: 771 STVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTL 830 Query: 570 TAKSHLFDGLDDD 582 + GL ++ Sbjct: 831 FTEDSTTSGLTEE 843 Score = 66.2 bits (160), Expect = 1e-10 Identities = 128/558 (22%), Positives = 214/558 (38%), Gaps = 82/558 (14%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TT+ G+ + +S G+ GT + + T GL G S S S +T T+T Sbjct: 863 TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGEST--------PSRLSPSSTETTTL 914 Query: 79 FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138 G T+ + T+ ++S + A P +T+S G+ ++T+ + Sbjct: 915 PGSPTTP-------SLSEKSTTFYTSPRSPDATLSP-------ATTTSSGVSEESSTSHS 960 Query: 139 PFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESK 198 GST + F S+ T+ + + G+ + ST S+ Q T Sbjct: 961 QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1020 Query: 199 SLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG-----LFSSSTTNSGFAYG 253 + L +D T+GL +S T S+TG L +S+T++G Sbjct: 1021 TETTLLPDD--------------TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEE 1066 Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313 S++ +P G + +T+ S+P ++T T FS +T T+G+ Sbjct: 1067 STTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRP----SSTPTTHFSASST-TLGRSEE 1121 Query: 314 NTMGLFGVTQASQPG----GLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFG--N 367 +T T S PG LF T + TS T + + + GST + Sbjct: 1122 ST------TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS 1175 Query: 368 NKLTTFGSS-----TTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNS--IF 420 K TTF SS TT +P+ T+SG + + + +T+T+ F T G S Sbjct: 1176 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 1235 Query: 421 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480 S +PG+ T L G TA G S ++ P G+ NTT + L Sbjct: 1236 ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSP------GSTETTLLPDNTTASGLLEA 1289 Query: 481 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 540 + + P+ + + + S T+ + P ++ M P PT +A Sbjct: 1290 STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW---PSSKDTMPAP--------PTTTSA 1338 Query: 541 QKALTTPTHYKLTPRPAT 558 L+T +H + P T Sbjct: 1339 FVELSTTSHGSPSSTPTT 1356 Score = 63.5 bits (153), Expect = 9e-10 Identities = 103/402 (25%), Positives = 165/402 (41%), Gaps = 70/402 (17%) Query: 19 TTSTFGQNTGFGT--TSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTS 76 +++T G++ T +S GA GT+ F + + T L G T P T + + P ++T+ Sbjct: 1112 SSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT 1171 Query: 77 TGFG-----FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKP-----TGFGNFGT---- 122 G F +S + +T AST TS S+ + + ++P T F T Sbjct: 1172 AGLSEKSTTFYSSPRSPDTTLSPAST-TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGV 1230 Query: 123 ---STSSGGLFGTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDT-MVKA 176 ST+S G+T+TT +P GST+ S GP S F ++P T P T + +++A Sbjct: 1231 SQESTASHSSPGSTDTTLSP-GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA 1289 Query: 177 GVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSS----P 232 + ST T + G + G TT + SS P Sbjct: 1290 STPVHSSTGSPHTT-------------------LSPAGSTTRQGESTTFQSWPSSKDTMP 1330 Query: 233 ATSSATGLF-SSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQ 291 A + T F STT+ G T F S+T G +++++T++ S P Sbjct: 1331 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG---------RSEESTTVHSSPVAT 1381 Query: 292 ATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351 ATT + TS + + ST G TQ + ++T++G + + T Sbjct: 1382 ATTPSP---ARSTTSGLVEESTAYHSSPGSTQT-----MHFPESSTASGRSEESRTSHSS 1433 Query: 352 QTNTGFGAVGSTLFGNNKLTTFGSS-----TTSAPSFGTTSG 388 T+T +T + T++ SS TT P TTSG Sbjct: 1434 TTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSG 1475 Score = 58.9 bits (141), Expect = 2e-08 Identities = 127/518 (24%), Positives = 201/518 (38%), Gaps = 66/518 (12%) Query: 28 GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84 G TT G + ++ F SS + T L S T G G T+S SQP ++ ST T+ Sbjct: 720 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 779 Query: 85 TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137 T + T++ ++ ST T++F S + +PT F + ST + LF +TTS Sbjct: 780 TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT-LFTEDSTTS 838 Query: 138 NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 G T S P S + TG TT + T T +S + + Sbjct: 839 ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 895 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244 + S + P + +T + S SPAT++++G+ S Sbjct: 896 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 955 Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP-------FGQATTTQN 297 +T+ + TAF STT + +Q +T P GQ +TT + Sbjct: 956 STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 1015 Query: 298 TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357 + S G+T T P G+ +AS P T++STG+ T T T+ G Sbjct: 1016 S--SPGDTETTLLPDDTITS--GLVEASTP-------THSSTGSLHTTLTPA-SSTSAGL 1063 Query: 358 GAVGSTLF---GNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNT 414 +T ++ T TT+AP +T+ + ++P+ T T+ + S+ G + Sbjct: 1064 QEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTT---YHSRPSSTPTTHFSASSTTLGRSE 1120 Query: 415 SGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTT 474 ++ S PG GT L F T P G T A PG TT Sbjct: 1121 ESTTVHSS---PGATGTAL---FPTRSATSVLVGEPTTSPISSGSTETTAL--PGSTTTA 1172 Query: 475 -----ATLGFGAPQAPVALTDPNASAAQQAVLQQHINS 507 +T + +P++P P AS V ++ S Sbjct: 1173 GLSEKSTTFYSSPRSPDTTLSP-ASTTSSGVSEESTTS 1209 Score = 38.1 bits (87), Expect = 0.039 Identities = 150/707 (21%), Positives = 251/707 (35%), Gaps = 126/707 (17%) Query: 71 PATSTSTGFGFGTST---GTANTLFGTASTGTSL-FSSQNNAFAQNKPTGFGNFGT---- 122 P +ST++G ++T T +T T ST +L +S +++ + T F + T Sbjct: 4 PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 63 Query: 123 ---STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVS 179 S +S TT P GST L G S+ + +G+ P T K G+S Sbjct: 64 SEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST---TKPGLS 120 Query: 180 TNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG 239 +T + ++ + P TT L PA+ +++G Sbjct: 121 EKSTT-----------------------FYSSPRSPD-------TTHL----PASMTSSG 146 Query: 240 LFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTG 299 + STT+ + TAF STT G + + T P +TT + G Sbjct: 147 VSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP--GSTTASSLG 204 Query: 300 FSF-------GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ 352 + G+T T P T G+ +AS P ++ST + T + Sbjct: 205 PEYTTFHSRPGSTETTLLPDNTTAS--GLLEASMP-------VHSSTRSPHTTLSPAGST 255 Query: 353 TNTGFGAVGSTLFGNNKLTTFGSSTTSA---PSFGTTSGGLFGNKPTLTLGTNTNTSNFG 409 T G + + +TTSA PS TTS G + PT + + TS Sbjct: 256 TRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPS--TTSHGSPSSIPTTHISARSTTSGLV 313 Query: 410 FGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPK---IGGPLGTGAF- 465 + T +S PG+ T T G G+ S ++ P T A Sbjct: 314 EESTTYHSS-------PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALV 366 Query: 466 -------GAPGFNTTT----ATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFG 514 +PG TT ++ G + A ++S + S T G Sbjct: 367 EEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA---SHSSQDATGTIVLPARSTTSVLLG 423 Query: 515 DSPLFRNPMSDPKKKEERL--KPTNPAAQKALTTPTHYKLTPR-PATRVRPKALQTTGTA 571 +S +P+S + L T P + TT + +PR PAT + P + ++G + Sbjct: 424 EST--TSPISSGSMETTALPGSTTTPGLSERSTT---FHSSPRSPATTLSPASTTSSGVS 478 Query: 572 KSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASPSEYPENG 631 + P + P + + ++ S+ SP + D+ L P+ +G Sbjct: 479 EE---STTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSH-SSPGSTDTTLL--PASTTTSG 532 Query: 632 ERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSNSNSV------D 685 S+ +H G D+ +S T ++ + + HSN S D Sbjct: 533 P-----SQESTTSHSSSGSTDTALSPGSTTALS-----FGQESTTFHSNPGSTHTTLFPD 582 Query: 686 DTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPA 732 T + + A+ R S T+ S + E+ ++ HPA Sbjct: 583 STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 629 >gi|24430146 nucleoporin 153kDa [Homo sapiens] Length = 1475 Score = 78.2 bits (191), Expect = 3e-14 Identities = 135/579 (23%), Positives = 210/579 (36%), Gaps = 124/579 (21%) Query: 3 NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGG- 61 + SF + G T T N FG G G S+ S N G +KP G Sbjct: 900 SSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE-GFKFSKPIGD 958 Query: 62 -LFGTSSFSQPAT----STSTGFGFGTSTGTANTL------FGTASTGTSLFSSQNNAFA 110 FG SS S+P S + F FG S+G +N + FG ++ G + Sbjct: 959 FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE---EKKEELP 1015 Query: 111 QNKPTGFGNFGT-------------------STSSGGLFGTTNTTSNPF----------- 140 ++ GF +FGT S+ + G T + + PF Sbjct: 1016 KSSSAGF-SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEE 1074 Query: 141 --GSTSGSLFG---PSSFTAAPT----GTTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 + G FG P+S +A T K P + ++V + N K Q + + Sbjct: 1075 MPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFS 1134 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQ-----------VGAGTTT--------------- 225 E E + + P + GA T+T Sbjct: 1135 FGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLN 1194 Query: 226 --GLFGSSPATSSATGLFSSSTTNSG-----FAYGQNK-----TAFGTSTTGFGTNPGGL 273 S+PATS+ G+F SST++S F +GQ+ +AFG +T T+ L Sbjct: 1195 NSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFG-NTAESSTSQSLL 1253 Query: 274 FGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGT 333 F Q ++ T+ +T T T F FG ++ +T+ G FG T Sbjct: 1254 FSQDSKLATT-------SSTGTAVTPFVFGPGASSNNTTTSGFG-FGAT----------- 1294 Query: 334 ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGN 393 T++S G++F GTG + S FG N+ TFG S ++ G + + Sbjct: 1295 TTSSSAGSSFVFGTGPSAPS-------ASPAFGANQTPTFGQSQGASQPNPPGFGSISSS 1347 Query: 394 KPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASL---FG 450 G+ FG +++S +FG +P+ G+G +A G ++ F Sbjct: 1348 TALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFT 1407 Query: 451 NNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALT 489 NN P G + + + GF Q+P A T Sbjct: 1408 NNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446 Score = 65.1 bits (157), Expect = 3e-10 Identities = 132/538 (24%), Positives = 195/538 (36%), Gaps = 114/538 (21%) Query: 34 GGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFG 93 G G F +S+++ +S K G +S SQ TST F FG G G Sbjct: 880 GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN-FKFGDQGGFK---IG 935 Query: 94 TASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSS------------GGLFGTTNTTSNPFG 141 +S S+ + + F +KP G FG S+ S FG ++ SNP Sbjct: 936 VSSDSGSI-NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVS 994 Query: 142 STSGSLFGPSSF------TAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEY 195 T FG S+ P ++ F+ TG A +T ++++++ + Sbjct: 995 LTPFQ-FGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI 1053 Query: 196 ESKSLE---------ELRLEDYQANRKG-----------PQNQVGAGTTTGLFGSSPATS 235 E+KS E + E+ A + G P V T P TS Sbjct: 1054 ETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTS 1113 Query: 236 SATGLFSSSTTNSG------FAYGQNKTA----FGTSTTGFG-TNPGGLFGQQNQQTTSL 284 ++ +F N F++G ++ ST F T P +Q + T Sbjct: 1114 TSL-VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFA 1172 Query: 285 FSKPFGQATTTQNTG-----FSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTST 339 F Q +TT + G FSF N S+ + T S GG+FG++T++S Sbjct: 1173 FG---AQTSTTADQGAAKPVFSFLNNSSSSSSTPAT---------SAGGGIFGSSTSSSN 1220 Query: 340 GTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTL 399 T +FGQ++ V S+ FGN T SST+ + F S K T Sbjct: 1221 PPV---ATFVFGQSSN---PVSSSAFGN----TAESSTSQSLLFSQDS------KLATTS 1264 Query: 400 GTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP 459 T T + F FG S N+ T G G GA T+ AG + +FG Sbjct: 1265 STGTAVTPFVFGPGASSNNTT-------TSGFGFGATT-TSSSAGSSFVFGT-------- 1308 Query: 460 LGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSP 517 G + +A+ FGA Q P AS +S P G P Sbjct: 1309 ---------GPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQP 1357 Score = 58.9 bits (141), Expect = 2e-08 Identities = 93/335 (27%), Positives = 136/335 (40%), Gaps = 52/335 (15%) Query: 36 AFGTSAFGSSNNTGGLFGNSQTKPGGLF---GTSSFSQPATSTSTGFGFGTSTGTANTLF 92 A T AFG+ +T G + KP F +SS S PATS G FG+ST ++N Sbjct: 1167 AKATFAFGAQTSTTADQGAA--KPVFSFLNNSSSSSSTPATSAGGGI-FGSSTSSSNP-- 1221 Query: 93 GTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTN----TTSNPFGSTSGSLF 148 T +F +N + + FGN S++S L + + TTS+ + + +F Sbjct: 1222 ---PVATFVFGQSSNPVSSS---AFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVF 1275 Query: 149 GPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDY 208 GP + + T + F T T AG S T +A + + + Sbjct: 1276 GPGASSNNTTTSGFGFG---ATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFG-QSQ 1331 Query: 209 QANRKGPQNQVGAGTTTGLF--GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGF 266 A++ P ++T LF GS PA + G SSS+ F +++AFG+ Sbjct: 1332 GASQPNPPGFGSISSSTALFPTGSQPAPPTF-GTVSSSSQPPVFGQQPSQSAFGS----- 1385 Query: 267 GTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQA-- 324 GT P ++S F FG +T T F+F N S G T G T A Sbjct: 1386 GTTP---------NSSSAFQ--FGSST----TNFNFTNNSPSG---VFTFGANSSTPAAS 1427 Query: 325 SQPGGLFGTATNTSTG--TAFGTGTGLFGQTNTGF 357 +QP G G N S T G +F + T F Sbjct: 1428 AQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462 Score = 51.2 bits (121), Expect = 4e-06 Identities = 80/285 (28%), Positives = 116/285 (40%), Gaps = 49/285 (17%) Query: 17 FGTTSTFGQNTGFGTTSGGAFGTS-----------AFGSSNN--TGGLFGN---SQTKPG 60 F S+ +T + GG FG+S FG S+N + FGN S T Sbjct: 1192 FLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS 1251 Query: 61 GLFGTSSFSQPATSTSTG-----FGFGTSTGTANTL-----FGTASTGTSLFSSQNNAFA 110 LF S S+ AT++STG F FG + NT FG +T +S SS Sbjct: 1252 LLF--SQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG 1309 Query: 111 QNKPTGFGNFGTSTSSGGLFGTTNTTSNP----FGSTSGS--LFGPSSFTAAPTGTTIKF 164 + P+ FG + + FG + S P FGS S S LF S A PT T+ Sbjct: 1310 PSAPSASPAFGANQTP--TFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSS 1367 Query: 165 N--PPT----GTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQ 218 + PP + + +G + N S+ Q ++ + + + + AN P Sbjct: 1368 SSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAAS 1427 Query: 219 VGAGTTTGL-FGSSPAT----SSATGLFSSSTTNSGFAYGQNKTA 258 + G F SPA S+ +FSSS T+ F+ + KTA Sbjct: 1428 AQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTS--FSGRKIKTA 1470 Score = 47.4 bits (111), Expect = 6e-05 Identities = 51/178 (28%), Positives = 75/178 (42%), Gaps = 38/178 (21%) Query: 3 NKSFGTPFGGGTG----------GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLF 52 + S G+ F GTG G T TFGQ+ G + FGS +++ LF Sbjct: 1297 SSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN-----PPGFGSISSSTALF 1351 Query: 53 GNSQTKPGGLFGT-SSFSQPAT----STSTGFGFGTSTGTANTL-FGTASTGTSLFSSQN 106 FGT SS SQP + + FG GT+ +++ FG+++T N Sbjct: 1352 PTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTT--------N 1403 Query: 107 NAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLF--GPSSFTAAPTGTTI 162 F N P+G FG ++S T ++ P GS G F P++FT G + Sbjct: 1404 FNFTNNSPSGVFTFGANSS------TPAASAQPSGS-GGFPFNQSPAAFTVGSNGKNV 1454 Score = 46.6 bits (109), Expect = 1e-04 Identities = 54/186 (29%), Positives = 76/186 (40%), Gaps = 23/186 (12%) Query: 8 TPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNT--GGLFGNSQTKPGGLFGT 65 T G G G T+S+ G + FGT + AFG++ G G SQ P G Sbjct: 1285 TTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI 1344 Query: 66 SSF-------SQPATSTSTGFGFGT-STGTANTLFG----TASTGTSLFSSQNNAFAQNK 113 SS SQPA T FGT S+ + +FG ++ G+ + ++AF Sbjct: 1345 SSSTALFPTGSQPAPPT-----FGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGS 1399 Query: 114 PTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTM 173 T NF T+ S G+F +S P S S G F +P T+ N G + Sbjct: 1400 STTNFNF-TNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSN---GKNVF 1455 Query: 174 VKAGVS 179 +G S Sbjct: 1456 SSSGTS 1461 >gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] Length = 587 Score = 75.1 bits (183), Expect = 3e-13 Identities = 108/475 (22%), Positives = 189/475 (39%), Gaps = 32/475 (6%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 TTS + + +S A GT + + T L G S T P + + P ++T+ G Sbjct: 61 TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 120 Query: 79 FGFGTST------GTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 ++T A TL ++T + + + ++ T F ST++ GL Sbjct: 121 LSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRH 180 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPT-GTTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 + T+ + GST +L S+ T+ P+ +T + P TDT + G +T +S + T Sbjct: 181 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTF 240 Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSST------ 245 S + +V + T + SPA+S++ GL ST Sbjct: 241 HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 300 Query: 246 --TNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303 T++ + TA +T + +PG + +S S ++T ++ + G Sbjct: 301 ASTHTTPSPPSTATAPVEESTTYHRSPGST-PTTHFPASSTTSGHSEKSTIFHSSPDASG 359 Query: 304 NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 T + +T+ + T SQPG TA ST T +GL + T + GST Sbjct: 360 TTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDST-----TTSGLSQEPTTSHSSQGST 414 Query: 364 LFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSK 423 T TT+AP +T+ + ++P+ T T+ + S+ G + ++ S Sbjct: 415 -EATLDTTPSPPGTTAAPVEVSTT---YHSRPSSTPTTHFSASSTTLGRSEESTTVHSS- 469 Query: 424 PAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIG----GPLGTGAFGAPGFNTTT 474 PG+ T G T G + S + P+ P T + G +TT+ Sbjct: 470 --PGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 522 Score = 66.6 bits (161), Expect = 1e-10 Identities = 99/417 (23%), Positives = 162/417 (38%), Gaps = 38/417 (9%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78 T+S + + + G+ T+AF S T GL +S T T + PA++T++G Sbjct: 145 TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 204 Query: 79 FGFGTST-----GTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLF-- 130 ++T G+ +T ST F ++ F + T F ST+S G+ Sbjct: 205 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 264 Query: 131 --------GTTNTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181 G+ TT +P STS L G S +F P T +PP+ V+ + + Sbjct: 265 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 324 Query: 182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241 S T + + S E P +GTT S A S+ +G+ Sbjct: 325 RSPGS---TPTTHFPASSTTSGHSEKSTIFHSSPD---ASGTT-----PSSAHSTTSGVS 373 Query: 242 SSSTTNSGFAYGQNKTAF--GTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTG 299 S+T+ + TAF T+T+G P Q +L + P TT Sbjct: 374 EESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVE 433 Query: 300 FSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGA 359 S T+ +PS+ F + + T ++S G+ T L G T T + Sbjct: 434 VS---TTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGST--ETTALPGSTTTAGLS 488 Query: 360 VGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSG 416 ST F ++ + TT +P+ T+SG + + + +T+T+ F T G Sbjct: 489 EKSTTFYSSPRS---PDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 542 Score = 54.7 bits (130), Expect = 4e-07 Identities = 107/441 (24%), Positives = 170/441 (38%), Gaps = 55/441 (12%) Query: 88 ANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSL 147 ++T G T+ SS + + T TS G+T TT P ST+ Sbjct: 6 SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 65 Query: 148 FGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTN--ISTKHQCITAMKEYESKSLEELRL 205 S+ + + T P + T V G ST IS+ TA+ + + Sbjct: 66 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 125 Query: 206 EDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTG 265 + ++ + P + SPA+++++G+ STT+ + TAF STT Sbjct: 126 TTFHSSPRSPATTL-----------SPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTT 174 Query: 266 FGTNPGGLFGQQNQQTT--------SLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMG 317 G + + +T + S P ++TT+ + S G+T T P + T Sbjct: 175 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHS---SPGSTDTALSPGSTTAL 231 Query: 318 LFG---VTQASQPGG----LFGTATNTS----TGTAFGTGTGLFGQTNTGFGAVGSTLFG 366 FG T S PG LF +T +S T + TG T + + L G Sbjct: 232 SFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG 291 Query: 367 -NNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGT-NTNTSNFGFGTNTSGNS----IF 420 + T +ST + PS +T+ T +T T++F + TSG+S IF Sbjct: 292 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 351 Query: 421 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480 S +P GT + T G + S ++QP G T AF P TT+ G Sbjct: 352 HS--SPDASGTTPSSAHSTTSGVSEESSTSHSQP---GSTHTTAF--PDSTTTS-----G 399 Query: 481 APQAPVALTDPNASAAQQAVL 501 Q P T ++ + +A L Sbjct: 400 LSQEPT--TSHSSQGSTEATL 418 >gi|89026265 PREDICTED: mucin 12 [Homo sapiens] Length = 978 Score = 73.6 bits (179), Expect = 8e-13 Identities = 151/606 (24%), Positives = 228/606 (37%), Gaps = 97/606 (16%) Query: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG-GLFGTSSFSQPA---TS 74 TT + T G + S GS++ T F S T PG T+S S P T+ Sbjct: 39 TTLSPASTTSSGVSEESTTSHSRPGSTHTTA--FPGSTTMPGVSQESTASHSSPGSTDTT 96 Query: 75 TSTGFGFGTSTGTANTLF--GTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132 S G +S G +T F G ST T+L T G ST G+ Sbjct: 97 LSPGSTTASSLGPESTTFHSGPGSTETTLLPDNT--------TASGLLEASTPVHSSTGS 148 Query: 133 TNTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191 +TT +P GST+ G S +F + P PPT T V+ +++ S T Sbjct: 149 PHTTLSPAGSTTRQ--GESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSS---TP 203 Query: 192 MKEYESKSLEELRLEDYQANRKGP-----QNQVGAGTTTGLFGSSPATSSATGL-----F 241 + + S R E+ P TT+GL S A S+ G F Sbjct: 204 TTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHF 263 Query: 242 SSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT-----TQ 296 S+T SG + +STT ++P ++ TS S P ATT + Sbjct: 264 PESSTASG--RSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESST 321 Query: 297 NTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG-----LFG 351 +G S +T++ P TN G+T F T+ + T F G L Sbjct: 322 TSGRSEESTASHSSPDTN-----GITPLP---AHFTTSGRIAESTTFYISPGSMETTLAS 373 Query: 352 QTNT-GFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTL-TLGTNTNTSNFG 409 T T G A + L+ +++ T +P+ TS + G +L + +T+T+ F Sbjct: 374 TTTTPGLSAKSTILYSSSR----SPDQTLSPA-SMTSSSISGEPTSLYSQAESTHTTAFP 428 Query: 410 FGTNTSG----NSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGT--- 462 T TSG ++ F SK PG+ T L G T Q ++QP G L T Sbjct: 429 ASTTTSGLSQESTTFHSK--PGSTETTLSPGSITTSSFAQEFTTPHSQP--GSALSTVSP 484 Query: 463 GAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNP 522 + PG + + T + +P + T+ A + + I+S +PF DSP F + Sbjct: 485 ASTTVPGLSEESTTF-YSSPGS----TETTAFSHSNTM---SIHSQQSTPFPDSPGFTHT 536 Query: 523 M------------------SDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA-TRVRPK 563 + S P A + PT + ++P P T + P Sbjct: 537 VLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPA 596 Query: 564 ALQTTG 569 + T+G Sbjct: 597 SSSTSG 602 Score = 50.8 bits (120), Expect = 6e-06 Identities = 110/501 (21%), Positives = 185/501 (36%), Gaps = 52/501 (10%) Query: 231 SPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFG 290 SPA+++++G+ STT+ + TAF STT G +Q++T+ S P Sbjct: 42 SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGV---------SQESTASHSSPGS 92 Query: 291 QATTT---QNTGFSFGNTSTI---GQPSTNTMGLFGVTQASQPGGLF--GTATNTSTGTA 342 TT T S G ST G ST T L T AS GL T ++STG+ Sbjct: 93 TDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTAS---GLLEASTPVHSSTGSP 149 Query: 343 FGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSA-PSFGTTSGGLFGNKPTLTLGT 401 T + T G + + T +TTSA TTS G + PT Sbjct: 150 HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA 209 Query: 402 NTNTSNFGFGTNTSGNS--IFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGP 459 ++ T + T +S + P+P T TA + S + P+ Sbjct: 210 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTA 269 Query: 460 LGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLF 519 G ++TT T+ P AL + S S+ + F +S Sbjct: 270 SGRSEESRTSHSSTTHTIS-SPPSTTSALVEEPTS------YHSSPGSIATTHFPES--- 319 Query: 520 RNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATR----VRPKALQTTGTAKSHL 575 + + +E ++P P H+ + R A + P +++TT A + Sbjct: 320 --STTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETT-LASTTT 376 Query: 576 FDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNS----NLFSPVNRDSENLASPSEYPENG 631 GL L + + P +++ + + + S +L+S + A P+ +G Sbjct: 377 TPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQA-ESTHTTAFPASTTTSG 435 Query: 632 ERFSFLSKPVDENHQQDGDEDSLVS--HFYTNPIAKPIPQTPESAGNKHSNSNSVDDTIV 689 LS+ H + G ++ +S T+ A+ G+ S + T+ Sbjct: 436 -----LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVP 490 Query: 690 ALNMRAALRNGLEGSSEETSF 710 L+ + GS+E T+F Sbjct: 491 GLSEESTTFYSSPGSTETTAF 511 Score = 47.0 bits (110), Expect = 8e-05 Identities = 94/381 (24%), Positives = 149/381 (39%), Gaps = 40/381 (10%) Query: 84 STGTANTLFGTASTGTSLFSSQNNAF--AQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFG 141 S+G+ T ST T+ S ++ F + P + ++TSSG +T + S P G Sbjct: 5 SSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRP-G 63 Query: 142 STSGSLF-GPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSL 200 ST + F G ++ +T + P TDT + G +T S + T S Sbjct: 64 STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTET 123 Query: 201 EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK-TAF 259 L P N T +GL +S S+TG ++ + +G Q + T F Sbjct: 124 TLL-----------PDNT----TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTF 168 Query: 260 GTSTTGFGTNPGGLFGQQNQQTTSLF----SKPFGQATTTQNTGFSFGNTSTIGQPSTNT 315 + T P TTS F + G ++T T FS +T+ + T Sbjct: 169 QSWPNSKDTTPA------PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT 222 Query: 316 MGLFGVTQASQPGGLFGTATN-TSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT-TF 373 + V A+ P T + TA+ + G T T ST G ++ + T Sbjct: 223 VHSSPVATATTPSPARSTTSGLVEESTAYHSSP---GSTQTMHFPESSTASGRSEESRTS 279 Query: 374 GSSTTSAPSFGTTSGGLFGNKPTLTLGT--NTNTSNFGFGTNTSGNS--IFGSKPAPGTL 429 SSTT S ++ +PT + + T++F + TSG S S +P T Sbjct: 280 HSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTN 339 Query: 430 G-TGLGAGFGTALGAGQASLF 449 G T L A F T+ +++ F Sbjct: 340 GITPLPAHFTTSGRIAESTTF 360 Score = 31.2 bits (69), Expect = 4.7 Identities = 55/237 (23%), Positives = 86/237 (36%), Gaps = 24/237 (10%) Query: 31 TTSG-GAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTSTGFGFGTSTG- 86 TT G A T + SS + + + G TS +SQ ++ +T F T+T Sbjct: 376 TTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSG 435 Query: 87 ------TANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT--------STSSGGLFGT 132 T ++ G+ T S S ++FAQ T G+ ST+ GL Sbjct: 436 LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 495 Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192 + T + GST + F S+ + + + F G V T + Sbjct: 496 STTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFH 555 Query: 193 KEYESKSLEELRLEDYQANRKGPQNQV---GAGTTTGLFGSSPATSSATGLFSSSTT 246 ++ L ++ G + T T LF PA+SS +GL STT Sbjct: 556 SSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLF---PASSSTSGLTEESTT 609 >gi|24497609 nucleoporin 62kDa [Homo sapiens] Length = 522 Score = 72.8 bits (177), Expect = 1e-12 Identities = 102/385 (26%), Positives = 143/385 (37%), Gaps = 76/385 (19%) Query: 7 GTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTS 66 G P GG T G T+T TGF +F TS G N + T GLF + Sbjct: 10 GAPTGGFTFGTAKTATTTPATGF------SFSTSGTGGFNFGAPFQPATSTPSTGLFSLA 63 Query: 67 SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF--AQNKPTGFGNFGTST 124 + PAT T TGF FGT+T + + G S + N A A P+GFG G+S Sbjct: 64 T-QTPATQT-TGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSN 120 Query: 125 SSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184 + + T TS+ + +G +FGPS+ + AP T+ F+ TG T +G Sbjct: 121 LTNAISST--VTSSQGTAPTGFVFGPSTTSVAPATTSGGFS-FTGGSTAQPSG------- 170 Query: 185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSS 244 + G Q A T ++PA ++A ++ Sbjct: 171 -----------------------FNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAA 207 Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGN 304 T TA TST SLF+ T++ TG S Sbjct: 208 PT---------PTATITST-----------------GPSLFASIATAPTSSATTGLSLCT 241 Query: 305 -TSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 +T G P+ T G PG GT+T TST A T T + TGF Sbjct: 242 PVTTAGAPTAGTQGF----SLKAPGAASGTSTTTST-AATATATTTSSSSTTGFALNLKP 296 Query: 364 LFGNNKLTTFGSSTTSAPSFGTTSG 388 L + ++ T+ P G +G Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAG 321 Score = 52.8 bits (125), Expect = 2e-06 Identities = 76/286 (26%), Positives = 105/286 (36%), Gaps = 61/286 (21%) Query: 221 AGTTTGLFGS--SPATSS-ATGLFS-----SSTTNSGFAYGQNKTAFG------------ 260 +GT FG+ PATS+ +TGLFS +T +GF +G A G Sbjct: 37 SGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASK 96 Query: 261 -----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT 315 T+ T NP G FG + T+ S + T TGF FG ++T P+T T Sbjct: 97 LNLSNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPAT-T 154 Query: 316 MGLFGVTQAS--QPGGL-FGTATN------------------------------TSTGTA 342 G F T S QP G G+A N T T T Sbjct: 155 SGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATI 214 Query: 343 FGTGTGLFGQTNTGFGAVGST-LFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGT 401 TG LF T + +T L +TT G+ T F + G T T Sbjct: 215 TSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTA 274 Query: 402 NTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQAS 447 T T+ ++T+G ++ AP + + A G G A+ Sbjct: 275 ATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAA 320 Score = 42.0 bits (97), Expect = 0.003 Identities = 63/206 (30%), Positives = 82/206 (39%), Gaps = 30/206 (14%) Query: 319 FGVTQASQPGGLFGTA----TNTSTGTAFGT-GTGLFGQTNTGFGAVGSTLFGNNKLTTF 373 FG T A G FGTA T +TG +F T GTG F A + G L T Sbjct: 6 FGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65 Query: 374 GSST-TSAPSFGTTSGGLFGNKPTLTLGTN-------------TNTSNFGFGTNTSGNSI 419 +T T+ +FGT + G +L +G + N S FG G++ N+I Sbjct: 66 TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125 Query: 420 FGS-KPAPGTLGTGLGAGFGT-----ALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 + + GT TG G T A +G S G + + G G+ G T Sbjct: 126 SSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSG-FNIGSAGNSAQPTA 184 Query: 474 TATLGFGAPQAPVALTDPNASAAQQA 499 ATL F P P A T A A Q A Sbjct: 185 PATLPF-TPATPAATT---AGATQPA 206 Score = 38.1 bits (87), Expect = 0.039 Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 29/208 (13%) Query: 5 SFGTPF--GGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG----NS 55 +FGT GGTG G G + NT G GSSN T + + Sbjct: 75 TFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSNLTNAISSTVTSSQ 133 Query: 56 QTKPGG-LFGTSSFSQPATSTSTGFGF---------GTSTGTANTLFGTASTGTSLFSSQ 105 T P G +FG S+ S +TS GF F G + G+A + T F+ Sbjct: 134 GTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPA 193 Query: 106 NNA---FAQNKPTGFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTT 161 A +P T TS+G LF + T +T SL P + APT T Sbjct: 194 TPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGT 253 Query: 162 IKFN-----PPTGTDTMVKAGVSTNIST 184 F+ +GT T + +T Sbjct: 254 QGFSLKAPGAASGTSTTTSTAATATATT 281 >gi|24497607 nucleoporin 62kDa [Homo sapiens] Length = 522 Score = 72.8 bits (177), Expect = 1e-12 Identities = 102/385 (26%), Positives = 143/385 (37%), Gaps = 76/385 (19%) Query: 7 GTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTS 66 G P GG T G T+T TGF +F TS G N + T GLF + Sbjct: 10 GAPTGGFTFGTAKTATTTPATGF------SFSTSGTGGFNFGAPFQPATSTPSTGLFSLA 63 Query: 67 SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF--AQNKPTGFGNFGTST 124 + PAT T TGF FGT+T + + G S + N A A P+GFG G+S Sbjct: 64 T-QTPATQT-TGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSN 120 Query: 125 SSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184 + + T TS+ + +G +FGPS+ + AP T+ F+ TG T +G Sbjct: 121 LTNAISST--VTSSQGTAPTGFVFGPSTTSVAPATTSGGFS-FTGGSTAQPSG------- 170 Query: 185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSS 244 + G Q A T ++PA ++A ++ Sbjct: 171 -----------------------FNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAA 207 Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGN 304 T TA TST SLF+ T++ TG S Sbjct: 208 PT---------PTATITST-----------------GPSLFASIATAPTSSATTGLSLCT 241 Query: 305 -TSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 +T G P+ T G PG GT+T TST A T T + TGF Sbjct: 242 PVTTAGAPTAGTQGF----SLKAPGAASGTSTTTST-AATATATTTSSSSTTGFALNLKP 296 Query: 364 LFGNNKLTTFGSSTTSAPSFGTTSG 388 L + ++ T+ P G +G Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAG 321 Score = 52.8 bits (125), Expect = 2e-06 Identities = 76/286 (26%), Positives = 105/286 (36%), Gaps = 61/286 (21%) Query: 221 AGTTTGLFGS--SPATSS-ATGLFS-----SSTTNSGFAYGQNKTAFG------------ 260 +GT FG+ PATS+ +TGLFS +T +GF +G A G Sbjct: 37 SGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASK 96 Query: 261 -----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT 315 T+ T NP G FG + T+ S + T TGF FG ++T P+T T Sbjct: 97 LNLSNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPAT-T 154 Query: 316 MGLFGVTQAS--QPGGL-FGTATN------------------------------TSTGTA 342 G F T S QP G G+A N T T T Sbjct: 155 SGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATI 214 Query: 343 FGTGTGLFGQTNTGFGAVGST-LFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGT 401 TG LF T + +T L +TT G+ T F + G T T Sbjct: 215 TSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTA 274 Query: 402 NTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQAS 447 T T+ ++T+G ++ AP + + A G G A+ Sbjct: 275 ATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAA 320 Score = 42.0 bits (97), Expect = 0.003 Identities = 63/206 (30%), Positives = 82/206 (39%), Gaps = 30/206 (14%) Query: 319 FGVTQASQPGGLFGTA----TNTSTGTAFGT-GTGLFGQTNTGFGAVGSTLFGNNKLTTF 373 FG T A G FGTA T +TG +F T GTG F A + G L T Sbjct: 6 FGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65 Query: 374 GSST-TSAPSFGTTSGGLFGNKPTLTLGTN-------------TNTSNFGFGTNTSGNSI 419 +T T+ +FGT + G +L +G + N S FG G++ N+I Sbjct: 66 TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125 Query: 420 FGS-KPAPGTLGTGLGAGFGT-----ALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 + + GT TG G T A +G S G + + G G+ G T Sbjct: 126 SSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSG-FNIGSAGNSAQPTA 184 Query: 474 TATLGFGAPQAPVALTDPNASAAQQA 499 ATL F P P A T A A Q A Sbjct: 185 PATLPF-TPATPAATT---AGATQPA 206 Score = 38.1 bits (87), Expect = 0.039 Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 29/208 (13%) Query: 5 SFGTPF--GGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG----NS 55 +FGT GGTG G G + NT G GSSN T + + Sbjct: 75 TFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSNLTNAISSTVTSSQ 133 Query: 56 QTKPGG-LFGTSSFSQPATSTSTGFGF---------GTSTGTANTLFGTASTGTSLFSSQ 105 T P G +FG S+ S +TS GF F G + G+A + T F+ Sbjct: 134 GTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPA 193 Query: 106 NNA---FAQNKPTGFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTT 161 A +P T TS+G LF + T +T SL P + APT T Sbjct: 194 TPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGT 253 Query: 162 IKFN-----PPTGTDTMVKAGVSTNIST 184 F+ +GT T + +T Sbjct: 254 QGFSLKAPGAASGTSTTTSTAATATATT 281 >gi|24497605 nucleoporin 62kDa [Homo sapiens] Length = 522 Score = 72.8 bits (177), Expect = 1e-12 Identities = 102/385 (26%), Positives = 143/385 (37%), Gaps = 76/385 (19%) Query: 7 GTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTS 66 G P GG T G T+T TGF +F TS G N + T GLF + Sbjct: 10 GAPTGGFTFGTAKTATTTPATGF------SFSTSGTGGFNFGAPFQPATSTPSTGLFSLA 63 Query: 67 SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF--AQNKPTGFGNFGTST 124 + PAT T TGF FGT+T + + G S + N A A P+GFG G+S Sbjct: 64 T-QTPATQT-TGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSN 120 Query: 125 SSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184 + + T TS+ + +G +FGPS+ + AP T+ F+ TG T +G Sbjct: 121 LTNAISST--VTSSQGTAPTGFVFGPSTTSVAPATTSGGFS-FTGGSTAQPSG------- 170 Query: 185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSS 244 + G Q A T ++PA ++A ++ Sbjct: 171 -----------------------FNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAA 207 Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGN 304 T TA TST SLF+ T++ TG S Sbjct: 208 PT---------PTATITST-----------------GPSLFASIATAPTSSATTGLSLCT 241 Query: 305 -TSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 +T G P+ T G PG GT+T TST A T T + TGF Sbjct: 242 PVTTAGAPTAGTQGF----SLKAPGAASGTSTTTST-AATATATTTSSSSTTGFALNLKP 296 Query: 364 LFGNNKLTTFGSSTTSAPSFGTTSG 388 L + ++ T+ P G +G Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAG 321 Score = 52.8 bits (125), Expect = 2e-06 Identities = 76/286 (26%), Positives = 105/286 (36%), Gaps = 61/286 (21%) Query: 221 AGTTTGLFGS--SPATSS-ATGLFS-----SSTTNSGFAYGQNKTAFG------------ 260 +GT FG+ PATS+ +TGLFS +T +GF +G A G Sbjct: 37 SGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASK 96 Query: 261 -----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT 315 T+ T NP G FG + T+ S + T TGF FG ++T P+T T Sbjct: 97 LNLSNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPAT-T 154 Query: 316 MGLFGVTQAS--QPGGL-FGTATN------------------------------TSTGTA 342 G F T S QP G G+A N T T T Sbjct: 155 SGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATI 214 Query: 343 FGTGTGLFGQTNTGFGAVGST-LFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGT 401 TG LF T + +T L +TT G+ T F + G T T Sbjct: 215 TSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTA 274 Query: 402 NTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQAS 447 T T+ ++T+G ++ AP + + A G G A+ Sbjct: 275 ATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAA 320 Score = 42.0 bits (97), Expect = 0.003 Identities = 63/206 (30%), Positives = 82/206 (39%), Gaps = 30/206 (14%) Query: 319 FGVTQASQPGGLFGTA----TNTSTGTAFGT-GTGLFGQTNTGFGAVGSTLFGNNKLTTF 373 FG T A G FGTA T +TG +F T GTG F A + G L T Sbjct: 6 FGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65 Query: 374 GSST-TSAPSFGTTSGGLFGNKPTLTLGTN-------------TNTSNFGFGTNTSGNSI 419 +T T+ +FGT + G +L +G + N S FG G++ N+I Sbjct: 66 TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125 Query: 420 FGS-KPAPGTLGTGLGAGFGT-----ALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 + + GT TG G T A +G S G + + G G+ G T Sbjct: 126 SSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSG-FNIGSAGNSAQPTA 184 Query: 474 TATLGFGAPQAPVALTDPNASAAQQA 499 ATL F P P A T A A Q A Sbjct: 185 PATLPF-TPATPAATT---AGATQPA 206 Score = 38.1 bits (87), Expect = 0.039 Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 29/208 (13%) Query: 5 SFGTPF--GGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG----NS 55 +FGT GGTG G G + NT G GSSN T + + Sbjct: 75 TFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSNLTNAISSTVTSSQ 133 Query: 56 QTKPGG-LFGTSSFSQPATSTSTGFGF---------GTSTGTANTLFGTASTGTSLFSSQ 105 T P G +FG S+ S +TS GF F G + G+A + T F+ Sbjct: 134 GTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPA 193 Query: 106 NNA---FAQNKPTGFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTT 161 A +P T TS+G LF + T +T SL P + APT T Sbjct: 194 TPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGT 253 Query: 162 IKFN-----PPTGTDTMVKAGVSTNIST 184 F+ +GT T + +T Sbjct: 254 QGFSLKAPGAASGTSTTTSTAATATATT 281 >gi|24497603 nucleoporin 62kDa [Homo sapiens] Length = 522 Score = 72.8 bits (177), Expect = 1e-12 Identities = 102/385 (26%), Positives = 143/385 (37%), Gaps = 76/385 (19%) Query: 7 GTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTS 66 G P GG T G T+T TGF +F TS G N + T GLF + Sbjct: 10 GAPTGGFTFGTAKTATTTPATGF------SFSTSGTGGFNFGAPFQPATSTPSTGLFSLA 63 Query: 67 SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF--AQNKPTGFGNFGTST 124 + PAT T TGF FGT+T + + G S + N A A P+GFG G+S Sbjct: 64 T-QTPATQT-TGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSN 120 Query: 125 SSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184 + + T TS+ + +G +FGPS+ + AP T+ F+ TG T +G Sbjct: 121 LTNAISST--VTSSQGTAPTGFVFGPSTTSVAPATTSGGFS-FTGGSTAQPSG------- 170 Query: 185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSS 244 + G Q A T ++PA ++A ++ Sbjct: 171 -----------------------FNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAA 207 Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGN 304 T TA TST SLF+ T++ TG S Sbjct: 208 PT---------PTATITST-----------------GPSLFASIATAPTSSATTGLSLCT 241 Query: 305 -TSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363 +T G P+ T G PG GT+T TST A T T + TGF Sbjct: 242 PVTTAGAPTAGTQGF----SLKAPGAASGTSTTTST-AATATATTTSSSSTTGFALNLKP 296 Query: 364 LFGNNKLTTFGSSTTSAPSFGTTSG 388 L + ++ T+ P G +G Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAG 321 Score = 52.8 bits (125), Expect = 2e-06 Identities = 76/286 (26%), Positives = 105/286 (36%), Gaps = 61/286 (21%) Query: 221 AGTTTGLFGS--SPATSS-ATGLFS-----SSTTNSGFAYGQNKTAFG------------ 260 +GT FG+ PATS+ +TGLFS +T +GF +G A G Sbjct: 37 SGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASK 96 Query: 261 -----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT 315 T+ T NP G FG + T+ S + T TGF FG ++T P+T T Sbjct: 97 LNLSNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPAT-T 154 Query: 316 MGLFGVTQAS--QPGGL-FGTATN------------------------------TSTGTA 342 G F T S QP G G+A N T T T Sbjct: 155 SGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATI 214 Query: 343 FGTGTGLFGQTNTGFGAVGST-LFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGT 401 TG LF T + +T L +TT G+ T F + G T T Sbjct: 215 TSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLKAPGAASGTSTTTSTA 274 Query: 402 NTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQAS 447 T T+ ++T+G ++ AP + + A G G A+ Sbjct: 275 ATATATTTSSSSTTGFALNLKPLAPAGIPSNTAAAVTAPPGPGAAA 320 Score = 42.0 bits (97), Expect = 0.003 Identities = 63/206 (30%), Positives = 82/206 (39%), Gaps = 30/206 (14%) Query: 319 FGVTQASQPGGLFGTA----TNTSTGTAFGT-GTGLFGQTNTGFGAVGSTLFGNNKLTTF 373 FG T A G FGTA T +TG +F T GTG F A + G L T Sbjct: 6 FGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGAPFQPATSTPSTGLFSLATQ 65 Query: 374 GSST-TSAPSFGTTSGGLFGNKPTLTLGTN-------------TNTSNFGFGTNTSGNSI 419 +T T+ +FGT + G +L +G + N S FG G++ N+I Sbjct: 66 TPATQTTGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFGLGSSNLTNAI 125 Query: 420 FGS-KPAPGTLGTGLGAGFGT-----ALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT 473 + + GT TG G T A +G S G + + G G+ G T Sbjct: 126 SSTVTSSQGTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSG-FNIGSAGNSAQPTA 184 Query: 474 TATLGFGAPQAPVALTDPNASAAQQA 499 ATL F P P A T A A Q A Sbjct: 185 PATLPF-TPATPAATT---AGATQPA 206 Score = 38.1 bits (87), Expect = 0.039 Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 29/208 (13%) Query: 5 SFGTPF--GGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG----NS 55 +FGT GGTG G G + NT G GSSN T + + Sbjct: 75 TFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSNLTNAISSTVTSSQ 133 Query: 56 QTKPGG-LFGTSSFSQPATSTSTGFGF---------GTSTGTANTLFGTASTGTSLFSSQ 105 T P G +FG S+ S +TS GF F G + G+A + T F+ Sbjct: 134 GTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPA 193 Query: 106 NNA---FAQNKPTGFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTT 161 A +P T TS+G LF + T +T SL P + APT T Sbjct: 194 TPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGT 253 Query: 162 IKFN-----PPTGTDTMVKAGVSTNIST 184 F+ +GT T + +T Sbjct: 254 QGFSLKAPGAASGTSTTTSTAATATATT 281 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.128 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,964,453 Number of Sequences: 37866 Number of extensions: 2131990 Number of successful extensions: 12346 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 93 Number of HSP's successfully gapped in prelim test: 226 Number of HSP's that attempted gapping in prelim test: 7225 Number of HSP's gapped (non-prelim): 2066 length of query: 937 length of database: 18,247,518 effective HSP length: 112 effective length of query: 825 effective length of database: 14,006,526 effective search space: 11555383950 effective search space used: 11555383950 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.