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Search of human proteins with 55742689
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55742689 actin filament associated protein 1-like 1 isoform
1 [Homo sapiens]
(768 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55742689 actin filament associated protein 1-like 1 isoform 1... 1544 0.0
gi|226437595 actin filament associated protein 1-like 1 isoform ... 1447 0.0
gi|40807504 actin filament associated protein 1 [Homo sapiens] 580 e-165
gi|197382472 actin filament associated protein 1 isoform a [Homo... 451 e-127
gi|50897850 KIAA1914 protein isoform 1 [Homo sapiens] 312 7e-85
gi|24308338 KIAA1914 protein isoform 2 [Homo sapiens] 312 7e-85
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 45 3e-04
gi|58530842 desmoplakin isoform II [Homo sapiens] 44 7e-04
gi|58530840 desmoplakin isoform I [Homo sapiens] 44 7e-04
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l... 44 7e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 44 7e-04
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 44 7e-04
gi|113425119 PREDICTED: similar to golgi autoantigen, golgin sub... 43 0.001
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 42 0.002
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 42 0.002
gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 42 0.002
gi|21735548 centrosomal protein 2 [Homo sapiens] 42 0.003
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 41 0.004
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 41 0.004
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 41 0.004
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein... 41 0.005
gi|157042792 coiled-coil domain containing 64B [Homo sapiens] 41 0.005
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l... 40 0.006
gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-l... 40 0.006
gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-l... 40 0.006
gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-l... 40 0.006
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 40 0.006
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] 40 0.008
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 40 0.008
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 40 0.011
>gi|55742689 actin filament associated protein 1-like 1 isoform 1
[Homo sapiens]
Length = 768
Score = 1544 bits (3998), Expect = 0.0
Identities = 768/768 (100%), Positives = 768/768 (100%)
Query: 1 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60
MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
Sbjct: 1 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60
Query: 61 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120
DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
Sbjct: 61 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120
Query: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180
PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
Sbjct: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180
Query: 181 DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL 240
DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
Sbjct: 181 DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL 240
Query: 241 TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS 300
TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
Sbjct: 241 TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS 300
Query: 301 REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC 360
REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC
Sbjct: 301 REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC 360
Query: 361 STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP 420
STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP
Sbjct: 361 STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP 420
Query: 421 CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF 480
CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF
Sbjct: 421 CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF 480
Query: 481 RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS 540
RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS
Sbjct: 481 RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS 540
Query: 541 FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR 600
FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR
Sbjct: 541 FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR 600
Query: 601 HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA 660
HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA
Sbjct: 601 HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA 660
Query: 661 KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGET 720
KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGET
Sbjct: 661 KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGET 720
Query: 721 ANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT 768
ANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
Sbjct: 721 ANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT 768
>gi|226437595 actin filament associated protein 1-like 1 isoform 2
[Homo sapiens]
Length = 725
Score = 1447 bits (3745), Expect = 0.0
Identities = 719/719 (100%), Positives = 719/719 (100%)
Query: 1 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60
MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
Sbjct: 1 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60
Query: 61 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120
DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
Sbjct: 61 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120
Query: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180
PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
Sbjct: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180
Query: 181 DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL 240
DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
Sbjct: 181 DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL 240
Query: 241 TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS 300
TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
Sbjct: 241 TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS 300
Query: 301 REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC 360
REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC
Sbjct: 301 REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC 360
Query: 361 STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP 420
STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP
Sbjct: 361 STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP 420
Query: 421 CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF 480
CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF
Sbjct: 421 CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF 480
Query: 481 RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS 540
RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS
Sbjct: 481 RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS 540
Query: 541 FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR 600
FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR
Sbjct: 541 FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR 600
Query: 601 HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA 660
HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA
Sbjct: 601 HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA 660
Query: 661 KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGE 719
KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGE
Sbjct: 661 KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGE 719
>gi|40807504 actin filament associated protein 1 [Homo sapiens]
Length = 730
Score = 580 bits (1495), Expect = e-165
Identities = 349/795 (43%), Positives = 462/795 (58%), Gaps = 103/795 (12%)
Query: 7 LEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTADLHSGP 66
+E+L+ EL L LLDHEYL+ T EKK + +IL +Q S
Sbjct: 1 MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQ------------------SSK 42
Query: 67 SFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNKPPPEDY 126
F D++D A+ N+ PP +P P+ +
Sbjct: 43 GF-------------DVKDH---------------AQKQETANSLPAPPQMPLPEIPQPW 74
Query: 127 YEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYNDSDAMS 186
LP G P P+ S+ +GYYE+A P E +S DSDAMS
Sbjct: 75 ----LPPDSGPPP---------LPTSSLPEGYYEEAVPLSPGKAP--EYITSNYDSDAMS 119
Query: 187 SSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQLTVIRED 246
SSYESYDEEEE+GK + RHQWPSEEASM LV++ +ICAFLLRKKRFGQW K L VI++
Sbjct: 120 SSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDT 179
Query: 247 QLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQSREQAEE 306
+LLCYKSSKD+QP + L L C+I Y+PKDS+ K+HEL+ TQ T+ LVLA+QS+EQAE+
Sbjct: 180 KLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQ 239
Query: 307 WLKVIREVSKPVGGAEGVEVPRSPVL-LCKLDLDKRLSQEKQTSDSDSVGVGDNCSTLGR 365
WLKVI+E G E P P + K +L+K+LS E+ +SD + V V + +T
Sbjct: 240 WLKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSSERPSSDGEGV-VENGITTCNG 298
Query: 366 RETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVPCCGYL 425
+E K KKSS +E KG++S+ G+KIT+II KKK D+ QTSS EE+VP CGYL
Sbjct: 299 KEQV---KRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDE-QTSSAEEDVPTCGYL 354
Query: 426 NVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAFRILRN 485
NVL N W+ERWCR+K N L FHKD DL+TH+ +I L+GCEV PG +HP FR+LRN
Sbjct: 355 NVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRN 414
Query: 486 RQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNSFL--- 542
QEVA+LEAS SEDMGRW+G+LL E GS PEALHYDY+DVE S++ + +F
Sbjct: 415 GQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQTFCFMN 474
Query: 543 --------YARSCQNQWPEPR----VYDDVPYEKMQDEEPERPTGAQ-VKRHASSCSEKS 589
Y N + P YDDVP + + P + V + S +
Sbjct: 475 RRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSLKGKKPPVASNGVTGKGKTLSSQP 534
Query: 590 HRVDPQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRE 649
+ DP VKR S+A QYKYGKNR E DA+R ++E+L K KE +R L LR+E+++
Sbjct: 535 KKADPAAVVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLAQLRKERKD 594
Query: 650 LKEAIRSSPGAKLKA-LEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALG 708
L+ AI + G K +A LEE + LE +CR KE R+ LEL+L VKE L+++LAGG LG
Sbjct: 595 LRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKALAGGVTLG 654
Query: 709 LSVSSKPKSGETA------------NKP----QNSVPEQPLPVNCVSELRKRSPSIVASN 752
L++ +PKSG ++ N P S E P+PVN + L+K + +S
Sbjct: 655 LAI--EPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKKSQAAPGSSP 712
Query: 753 -QGRVLQKAKEWEMK 766
+G VL+KAKEWE+K
Sbjct: 713 CRGHVLRKAKEWELK 727
>gi|197382472 actin filament associated protein 1 isoform a [Homo
sapiens]
Length = 814
Score = 451 bits (1161), Expect = e-127
Identities = 261/571 (45%), Positives = 335/571 (58%), Gaps = 82/571 (14%)
Query: 7 LEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTADLHSGP 66
+E+L+ EL L LLDHEYL+ T EKK + +IL +Q S
Sbjct: 1 MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQ------------------SSK 42
Query: 67 SFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNKPPPEDY 126
F D++D A+ N+ PP +P P+ +
Sbjct: 43 GF-------------DVKDH---------------AQKQETANSLPAPPQMPLPEIPQPW 74
Query: 127 YEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYNDSDAMS 186
LP G P P+ S+ +GYYE+A P E +S DSDAMS
Sbjct: 75 ----LPPDSGPPP---------LPTSSLPEGYYEEAVPLSPGKAP--EYITSNYDSDAMS 119
Query: 187 SSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQLTVIRED 246
SSYESYDEEEE+GK + RHQWPSEEASM LV++ +ICAFLLRKKRFGQW K L VI++
Sbjct: 120 SSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDT 179
Query: 247 QLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQSREQAEE 306
+LLCYKSSKD+QP + L L C+I Y+PKDS+ K+HEL+ TQ T+ LVLA+QS+EQAE+
Sbjct: 180 KLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQ 239
Query: 307 WLKVIREVSKPVGGAEGVEVPRSPVL-LCKLDLDKRLSQEKQTSDSDSVGVGDNCSTLGR 365
WLKVI+E G E P P + K +L+K+LS E+ +SD + V V + +T
Sbjct: 240 WLKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSSERPSSDGEGV-VENGITTCNG 298
Query: 366 RETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVPCCGYL 425
+E K KKSS +E KG++S+ G+KIT+II KKK D+ QTSS EE+VP CGYL
Sbjct: 299 KEQV---KRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDE-QTSSAEEDVPTCGYL 354
Query: 426 NVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAFRILRN 485
NVL N W+ERWCR+K N L FHKD DL+TH+ +I L+GCEV PG +HP FR+LRN
Sbjct: 355 NVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRN 414
Query: 486 RQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNSFL--- 542
QEVA+LEAS SEDMGRW+G+LL E GS PEALHYDY+DVE S++ + +F
Sbjct: 415 GQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQTFCFMN 474
Query: 543 --------YARSCQNQWPEPR----VYDDVP 561
Y N + P YDDVP
Sbjct: 475 RRVISANPYLGGTSNGYAHPSGTALHYDDVP 505
Score = 141 bits (356), Expect = 2e-33
Identities = 104/295 (35%), Positives = 153/295 (51%), Gaps = 24/295 (8%)
Query: 494 ASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGR---NSFLYARSCQNQ 550
ASCS +G + + + P + Y + S +SA + N + Y S Q+
Sbjct: 519 ASCSRGLGEEVLYDNAGLYDNLPPPHIFARYSPADRKASRLSADKLSSNHYKYPASAQSV 578
Query: 551 WPEPRVYDDVPYEKMQDEEPERPTGAQ-VKRHASSCSEKSHRVDPQVKVKRHASSANQYK 609
V Q + + P + V + S + + DP VKR S+A QYK
Sbjct: 579 TNTSSVGRASLGLNSQLKGKKPPVASNGVTGKGKTLSSQPKKADPAAVVKRTGSNAAQYK 638
Query: 610 YGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKA-LEEA 668
YGKNR E DA+R ++E+L K KE +R L LR+E+++L+ AI + G K +A LEE
Sbjct: 639 YGKNRVEADAKRLQTKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKPQAILEEK 698
Query: 669 VATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETA------- 721
+ LE +CR KE R+ LEL+L VKE L+++LAGG LGL++ +PKSG ++
Sbjct: 699 LKQLEEECRQKEAERVSLELELTEVKESLKKALAGGVTLGLAI--EPKSGTSSPQSPVFR 756
Query: 722 -----NKP----QNSVPEQPLPVNCVSELRKRSPSIVASN-QGRVLQKAKEWEMK 766
N P S E P+PVN + L+K + +S +G VL+KAKEWE+K
Sbjct: 757 HRTLENSPISSCDTSDTEGPVPVNSAAVLKKSQAAPGSSPCRGHVLRKAKEWELK 811
>gi|50897850 KIAA1914 protein isoform 1 [Homo sapiens]
Length = 818
Score = 312 bits (800), Expect = 7e-85
Identities = 214/575 (37%), Positives = 303/575 (52%), Gaps = 81/575 (14%)
Query: 1 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60
M+R + LEQLL EL L +LD E LS T L KK +A +L+ + + Y+Y+N
Sbjct: 1 MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
Query: 61 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120
++ + PE+ G G + + +P+ ++ DLPPP K
Sbjct: 61 TINKQQN------------AESQGKAPEEQGLLPNGEPSQHSSAPQ-KSLPDLPPP---K 104
Query: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180
PE + L + +SPE GYYE+A+ + +GE
Sbjct: 105 MIPE---RKQLAIPKTESPE----------------GYYEEAEPYDTSLNEDGE------ 139
Query: 181 DSDAMSSSYESYDEEE-EEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQ 239
A+SSSYESYDEE+ +GKS +QWPS EA + L+R+ RICAFL RKK GQWAKQ
Sbjct: 140 ---AVSSSYESYDEEDGSKGKSAP--YQWPSPEAGIELMRDARICAFLWRKKWLGQWAKQ 194
Query: 240 LTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQ 299
L VI++++LLCYKSSKD P L + L S+I+ K R K H+L+ T +V+VL LQ
Sbjct: 195 LCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLKITPMNADVIVLGLQ 254
Query: 300 SREQAEEWLKVIREVS--KPVGGAEGVE-VPRSPVLLC-KLDL-DKRLSQEKQTSDSDSV 354
S++QAE+WL+VI+EVS G +EG + P + C K D+ +K LS + S D
Sbjct: 255 SKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEKYLSASEYGSSVD-- 312
Query: 355 GVGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSS 414
G E + KK +AG K++ ++ +KK+ +
Sbjct: 313 ---------GHPEVPETKDVKKKC----------SAGLKLSNLMNLGRKKSTS----LEP 349
Query: 415 TEEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGP 474
E + YLNVLVN WK RWC ++ N L+F++D + ++L GCEV P P
Sbjct: 350 VERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSP 409
Query: 475 RHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIV 534
H ++FRIL +E+A LEA SE+MG WLGLLL E GS+ PE YDYVD + ++ IV
Sbjct: 410 DHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIV 469
Query: 535 SAGRNSFLYARSCQNQWPEPRVY-DDVPYEKMQDE 568
SA +NS L Q ++ EP Y D +P + Q+E
Sbjct: 470 SAAKNSLLL---MQRKFSEPNTYIDGLPSQDRQEE 501
Score = 127 bits (319), Expect = 4e-29
Identities = 76/182 (41%), Positives = 111/182 (60%), Gaps = 16/182 (8%)
Query: 594 PQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEA 653
P VK + +SA + K GKNR E + +RY EKE+LEK+KE IR L LR+EKRELKE
Sbjct: 641 PPVKDRLRVTSA-EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKET 699
Query: 654 -IRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGL--- 709
++ + L +LE+ + ++ +CR +E RR+DLEL ++ VK+ L+++ AG LG
Sbjct: 700 LLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVD 759
Query: 710 -----SVSSKPKSGETANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWE 764
+VS +PK+ A+ P + PVN + L+ R S+V + +G VLQKAKEWE
Sbjct: 760 TTHLENVSPRPKAVTPASAPDCT------PVNSATTLKNRPLSVVVTGKGTVLQKAKEWE 813
Query: 765 MK 766
K
Sbjct: 814 KK 815
>gi|24308338 KIAA1914 protein isoform 2 [Homo sapiens]
Length = 814
Score = 312 bits (800), Expect = 7e-85
Identities = 214/575 (37%), Positives = 303/575 (52%), Gaps = 81/575 (14%)
Query: 1 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA 60
M+R + LEQLL EL L +LD E LS T L KK +A +L+ + + Y+Y+N
Sbjct: 1 MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSSDEEYIYMNKV 60
Query: 61 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK 120
++ + PE+ G G + + +P+ ++ DLPPP K
Sbjct: 61 TINKQQN------------AESQGKAPEEQGLLPNGEPSQHSSAPQ-KSLPDLPPP---K 104
Query: 121 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN 180
PE + L + +SPE GYYE+A+ + +GE
Sbjct: 105 MIPE---RKQLAIPKTESPE----------------GYYEEAEPYDTSLNEDGE------ 139
Query: 181 DSDAMSSSYESYDEEE-EEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQ 239
A+SSSYESYDEE+ +GKS +QWPS EA + L+R+ RICAFL RKK GQWAKQ
Sbjct: 140 ---AVSSSYESYDEEDGSKGKSAP--YQWPSPEAGIELMRDARICAFLWRKKWLGQWAKQ 194
Query: 240 LTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQ 299
L VI++++LLCYKSSKD P L + L S+I+ K R K H+L+ T +V+VL LQ
Sbjct: 195 LCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLKITPMNADVIVLGLQ 254
Query: 300 SREQAEEWLKVIREVS--KPVGGAEGVE-VPRSPVLLC-KLDL-DKRLSQEKQTSDSDSV 354
S++QAE+WL+VI+EVS G +EG + P + C K D+ +K LS + S D
Sbjct: 255 SKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEKYLSASEYGSSVD-- 312
Query: 355 GVGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSS 414
G E + KK +AG K++ ++ +KK+ +
Sbjct: 313 ---------GHPEVPETKDVKKKC----------SAGLKLSNLMNLGRKKSTS----LEP 349
Query: 415 TEEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGP 474
E + YLNVLVN WK RWC ++ N L+F++D + ++L GCEV P P
Sbjct: 350 VERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSP 409
Query: 475 RHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIV 534
H ++FRIL +E+A LEA SE+MG WLGLLL E GS+ PE YDYVD + ++ IV
Sbjct: 410 DHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIV 469
Query: 535 SAGRNSFLYARSCQNQWPEPRVY-DDVPYEKMQDE 568
SA +NS L Q ++ EP Y D +P + Q+E
Sbjct: 470 SAAKNSLLL---MQRKFSEPNTYIDGLPSQDRQEE 501
Score = 127 bits (319), Expect = 4e-29
Identities = 75/178 (42%), Positives = 110/178 (61%), Gaps = 12/178 (6%)
Query: 594 PQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEA 653
P VK + +SA + K GKNR E + +RY EKE+LEK+KE IR L LR+EKRELKE
Sbjct: 641 PPVKDRLRVTSA-EIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKET 699
Query: 654 -IRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVS 712
++ + L +LE+ + ++ +CR +E RR+DLEL ++ VK+ L+++ AG LG +V
Sbjct: 700 LLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVD 759
Query: 713 S----KPKSGETANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMK 766
+ PK+ A+ P + PVN + L+ R S+V + +G VLQKAKEWE K
Sbjct: 760 TTHLENPKAVTPASAPDCT------PVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKK 811
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 44.7 bits (104), Expect = 3e-04
Identities = 44/193 (22%), Positives = 86/193 (44%), Gaps = 24/193 (12%)
Query: 551 WPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKY 610
W + R+ + V + E + A V+ A++ E+ +++ + +A +
Sbjct: 788 WEQARLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQSEAAEERM- 846
Query: 611 GKNRAEEDARRYLVEKEKLEKEKETIRTEL-----------IALRQEKRELKEAI----- 654
E + R++L E E+ +EKE ++ EL L +REL++A
Sbjct: 847 --QVLESEGRQHLEEAERERREKEALQAELEKAVVRGKELGARLEHLQRELEQAALERQE 904
Query: 655 ----RSSPGAKLKALEEAV-ATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGL 709
+ S + + LE+ + A L+A +KEE ++L+ + + ++E L Q G LG
Sbjct: 905 FLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPAGLGP 964
Query: 710 SVSSKPKSGETAN 722
++P+ ET N
Sbjct: 965 KKRAEPQLVETQN 977
Score = 35.8 bits (81), Expect = 0.15
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 6/126 (4%)
Query: 567 DEEPERPTGAQVKRHASSCSEK----SHRVDPQ-VKVKRHASSANQYKYGKNRAEEDARR 621
++E R AQ++R A + ++ + +++ Q + R + Q + + A +A
Sbjct: 726 EQEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHREAEA 785
Query: 622 YLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEE 681
E+ +L + E EL + QE+ L EA+ ++ G + + E + L AQ A EE
Sbjct: 786 QAWEQARLREAVEAAGQELESASQEREALVEAL-AAAGRERRQWEREGSRLRAQSEAAEE 844
Query: 682 RRIDLE 687
R LE
Sbjct: 845 RMQVLE 850
>gi|58530842 desmoplakin isoform II [Homo sapiens]
Length = 2272
Score = 43.5 bits (101), Expect = 7e-04
Identities = 31/109 (28%), Positives = 58/109 (53%), Gaps = 12/109 (11%)
Query: 582 ASSCSEKSHRVDPQVKVKRHA--SSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTE 639
A S E RV +++ ++ + NQ+K +R EE R+ E+EK E+EK ++R+E
Sbjct: 1240 AKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSE 1299
Query: 640 LIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQC---RAKEERRID 685
+ L+ E + ++E R + LE++ ++Q R++ +R ID
Sbjct: 1300 IERLQAEIKRIEERCR-------RKLEDSTRETQSQLETERSRYQREID 1341
Score = 31.6 bits (70), Expect = 2.9
Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 14/103 (13%)
Query: 613 NRAEEDARRYLVEKEKLEKEKETIRTEL-------------IALRQEKRELKEAIRSSPG 659
NRA+ K++LE EK+ I+ +L I + +RE E ++S
Sbjct: 1238 NRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLR 1297
Query: 660 AKLKALEEAVATLEAQCRAK-EERRIDLELKLVAVKERLQQSL 701
++++ L+ + +E +CR K E+ + + +L + R Q+ +
Sbjct: 1298 SEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREI 1340
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 43.5 bits (101), Expect = 7e-04
Identities = 31/109 (28%), Positives = 58/109 (53%), Gaps = 12/109 (11%)
Query: 582 ASSCSEKSHRVDPQVKVKRHA--SSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTE 639
A S E RV +++ ++ + NQ+K +R EE R+ E+EK E+EK ++R+E
Sbjct: 1839 AKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSE 1898
Query: 640 LIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQC---RAKEERRID 685
+ L+ E + ++E R + LE++ ++Q R++ +R ID
Sbjct: 1899 IERLQAEIKRIEERCR-------RKLEDSTRETQSQLETERSRYQREID 1940
Score = 34.3 bits (77), Expect = 0.45
Identities = 33/140 (23%), Positives = 69/140 (49%), Gaps = 24/140 (17%)
Query: 577 QVKRHASSCSEKSHRVDPQ------------VKVKRHASSANQYKYGKNRAEEDARR--- 621
++KR AS S K +++ + +K+ Q K R+E+D R+
Sbjct: 1579 RLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRD 1638
Query: 622 ----YLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCR 677
+L EK++ ++E + +E+ ALR++ + +E+++ A L+ E +E + R
Sbjct: 1639 VLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQ---AHLRN-EHFQKAIEDKSR 1694
Query: 678 AKEERRIDLELKLVAVKERL 697
+ E +I++E +L ++ E L
Sbjct: 1695 SLNESKIEIE-RLQSLTENL 1713
Score = 31.6 bits (70), Expect = 2.9
Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 14/103 (13%)
Query: 613 NRAEEDARRYLVEKEKLEKEKETIRTEL-------------IALRQEKRELKEAIRSSPG 659
NRA+ K++LE EK+ I+ +L I + +RE E ++S
Sbjct: 1837 NRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLR 1896
Query: 660 AKLKALEEAVATLEAQCRAK-EERRIDLELKLVAVKERLQQSL 701
++++ L+ + +E +CR K E+ + + +L + R Q+ +
Sbjct: 1897 SEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREI 1939
>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 43.5 bits (101), Expect = 7e-04
Identities = 38/172 (22%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRY 622
E + E P P+ +++ + + QVK +H S N+ + + R E R
Sbjct: 293 EPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQ--EERIREQEERL 350
Query: 623 LVEKEKLEKEKETIRTELIALRQEKRELKEAIRSS--PGAKLKALEEAVATLEAQCRAKE 680
++E+L+++ E +R +L + EL +S+ ++K L+E + + +++
Sbjct: 351 RKQEERLQEQHEKLR-QLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQ 409
Query: 681 ERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQP 732
+++ +L L+A+ P G GE A +P SVPE P
Sbjct: 410 NQQLTAQLSLMAL-----------PGEGHGGEHLDSEGEEAPRPMPSVPEDP 450
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 43.5 bits (101), Expect = 7e-04
Identities = 30/122 (24%), Positives = 57/122 (46%), Gaps = 4/122 (3%)
Query: 562 YEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARR 621
+EKM++E+ ER + + A D ++ +R A + K A+E RR
Sbjct: 254 HEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEE----KAAAQERERR 309
Query: 622 YLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEE 681
E+E++ +E++ E +++E++ E + + +A EE E + RA EE
Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 369
Query: 682 RR 683
R+
Sbjct: 370 RQ 371
Score = 40.0 bits (92), Expect = 0.008
Identities = 37/137 (27%), Positives = 64/137 (46%), Gaps = 11/137 (8%)
Query: 564 KMQDEEPERPTGAQVKRHASSCS--EKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARR 621
+++ EE ER Q K+ A + E + Q + +R A + + + RA E+ +R
Sbjct: 271 RLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR 330
Query: 622 YLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAK-- 679
E+++ +E++ I+ E EKR +E R K A E A E + +AK
Sbjct: 331 IKEEEKRAAEERQRIKEE------EKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE 384
Query: 680 -EERRIDLELKLVAVKE 695
++R LE K A++E
Sbjct: 385 EQKRNKQLEEKKHAMQE 401
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 43.5 bits (101), Expect = 7e-04
Identities = 56/222 (25%), Positives = 89/222 (40%), Gaps = 40/222 (18%)
Query: 566 QDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRYLVE 625
+ EE +R A+ ++ E+ R++ Q + +R A Q + + R E++ +R L E
Sbjct: 383 EQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREAR--RQQEREQRRREQEEKRRLEE 440
Query: 626 KEKLEKEKETIR-----TELIALRQE--KRELKEAIRSSPGAKLKALEEAVATLEAQCRA 678
E+ KE+E R + QE +R+L+E R + + L+E LE + R
Sbjct: 441 LERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWRE 500
Query: 679 KEERRIDLELKLVAVKERLQQSLAGGPALGLSV------------SSKPKSGETANKPQN 726
EE R ERLQ+ L A LS+ P + +KP
Sbjct: 501 MEEHR---------QAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSF 551
Query: 727 SVPEQPL---PVNCVSELRKR-------SPSIVASNQGRVLQ 758
PE P + E+ R SP + GRVL+
Sbjct: 552 HAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLE 593
Score = 35.0 bits (79), Expect = 0.26
Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 15/149 (10%)
Query: 540 SFLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVK 599
SF+ +N P + + ++D+ ER Q+K H + + K
Sbjct: 264 SFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHID-----------RTRKK 312
Query: 600 RHASSANQYKY-GKNRAEEDARRYLVEKEKLEKE--KETIRTELIALRQEKRELKEAIRS 656
R +Y+Y G EE+ E + + T+R + + L+QE +E EA+R
Sbjct: 313 RGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRR 372
Query: 657 SPGAKLKALEEAVATLEAQCRAKEERRID 685
+ + L E + Q A+ ++RI+
Sbjct: 373 QQLLQEQQLREQ-EEYKRQLLAERQKRIE 400
>gi|113425119 PREDICTED: similar to golgi autoantigen, golgin
subfamily a, 8E isoform 2 [Homo sapiens]
Length = 631
Score = 42.7 bits (99), Expect = 0.001
Identities = 38/172 (22%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRY 622
E + E P P+ +++ + + QVK +H S N+ + + R E R
Sbjct: 292 EPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQ--EERIREQEERL 349
Query: 623 LVEKEKLEKEKETIRTELIALRQEKRELKEAIRSS--PGAKLKALEEAVATLEAQCRAKE 680
++E+L+++ E +R +L + EL +S+ ++K L+E + + +++
Sbjct: 350 RKQEERLQEQHEKLR-QLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEVASQQ 408
Query: 681 ERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQP 732
+++ +L L+A+ P G GE A +P SVPE P
Sbjct: 409 NQQLTAQLSLMAL-----------PGEGHGGEHLDSEGEEAPQPMPSVPEDP 449
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 617 EDARRYLVEKEKL-----EKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVAT 671
E + ++ E E L +KE R ELI L+ + ++++ P + +K LEE +
Sbjct: 897 EKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAK-SPSVKNDPLSSVKELEEKIEN 955
Query: 672 LEAQCRAKEERRIDLELKLVAVKERLQQS 700
LE +C+ KEE+ ++L V K+ L S
Sbjct: 956 LEKECKEKEEKINKIKLVAVKAKKELDSS 984
Score = 32.7 bits (73), Expect = 1.3
Identities = 38/177 (21%), Positives = 80/177 (45%), Gaps = 19/177 (10%)
Query: 527 VETLTSIVSAGRNSFLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCS 586
+ETL S L + + Q + V ++ EK+Q E+ ++K HA++ +
Sbjct: 1075 IETLQS-----NAKLLEVQILEVQRAKAMVDKELEAEKLQKEQ-------KIKEHATTVN 1122
Query: 587 EKSH-RVDPQVKVKRHASSANQYKYGKNRAEEDA--RRYLVEKEKLEKEKETIRTELIAL 643
E +V Q + K+ + + + K A++ + + E+L KE + +L
Sbjct: 1123 ELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKE---LNQKLTNK 1179
Query: 644 RQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQS 700
+ +L++ I+ K + L+E + +L++ + EE+ ++ LV K+ L S
Sbjct: 1180 NNKIEDLEQEIKIQK-QKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADS 1235
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/186 (23%), Positives = 74/186 (39%), Gaps = 6/186 (3%)
Query: 568 EEPERPTGAQ--VKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKN---RAEEDARRY 622
EE + P A+ VK A S +E + K A S + K + ++ E A+
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP 669
Query: 623 L-VEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEE 681
+ E + EK K ++ E + + K +KE +S AK EEA + +A+ KEE
Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 729
Query: 682 RRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQPLPVNCVSEL 741
+ + K +E A P ++ K +T K + P P S +
Sbjct: 730 AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPV 789
Query: 742 RKRSPS 747
++ S
Sbjct: 790 KEEVKS 795
Score = 39.7 bits (91), Expect = 0.011
Identities = 44/171 (25%), Positives = 67/171 (39%), Gaps = 13/171 (7%)
Query: 561 PYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYG-KNRAEEDA 619
P E E+ + P VK A S +E V + K S + K K A+
Sbjct: 595 PAEAKSPEKAKSP----VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650
Query: 620 RRYLVEKEKL---EKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQC 676
+ EKE+ EK K ++ E + + K +K +S AK EEA + +A+
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS 710
Query: 677 RAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNS 727
KEE + + K +E A P V + KS E A P+ +
Sbjct: 711 PVKEEAKSPEKAKSPVKEEAKTPEKAKSP-----VKEEAKSPEKAKSPEKA 756
Score = 37.4 bits (85), Expect = 0.053
Identities = 37/129 (28%), Positives = 52/129 (40%), Gaps = 9/129 (6%)
Query: 625 EKEKLEKEKETIRTELIALRQEKRELKEA--IRSSPGAKLKALEEAVATLEAQCRAKEER 682
EKE KE ++ A EK E K ++S AK A EEA + EA+ KEE
Sbjct: 513 EKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEA 572
Query: 683 RIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQPLPVNCVSELR 742
+ E+K + + A PA + KS E A P + P +
Sbjct: 573 KSPAEVKSPEKAKSPAKEEAKSPA-------EAKSPEKAKSPVKEEAKSPAEAKSPVKEE 625
Query: 743 KRSPSIVAS 751
+SP+ V S
Sbjct: 626 AKSPAEVKS 634
Score = 34.7 bits (78), Expect = 0.34
Identities = 43/190 (22%), Positives = 72/190 (37%), Gaps = 20/190 (10%)
Query: 561 PYEKMQDEEPERPTGAQVKRHASSCS-EKSHRVDPQVKVKRHASSANQYKYGKNRAEEDA 619
P E E+ + PT + K + S EK P+ + A + K+ + +A
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688
Query: 620 RRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAK 679
+ EK K ++ E + + K +KE +S AK EEA +A+ K
Sbjct: 689 K-------SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741
Query: 680 EERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQ---PLPVN 736
EE + + K + L S +K + E A P + PE+ P+
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVK---------SPEAKTPAKEEARSPADKFPEKAKSPVKEE 792
Query: 737 CVSELRKRSP 746
S + +SP
Sbjct: 793 VKSPEKAKSP 802
Score = 30.0 bits (66), Expect = 8.4
Identities = 37/133 (27%), Positives = 50/133 (37%), Gaps = 13/133 (9%)
Query: 88 EDDGEPSKGASPELAKSPRLRNAADLPPPLPNKPPPEDYYEEALPLGPGKSPEYISS--- 144
E+ P++ SPE AKSP A P K P + EEA KSPE S
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKS---PAEAKSPVK---EEAKSPAEVKSPEKAKSPTK 643
Query: 145 HNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYNDSDAMSSSYESYDEE----EEEGK 200
SP + E + V E KS + + +S ++ +EE K
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703
Query: 201 SPQPRHQWPSEEA 213
SP+ EEA
Sbjct: 704 SPEKAKSPVKEEA 716
>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
Length = 1060
Score = 42.0 bits (97), Expect = 0.002
Identities = 41/150 (27%), Positives = 74/150 (49%), Gaps = 14/150 (9%)
Query: 560 VPYEKMQDEEPERPTGAQVKRHASSCSEKSH--RVDPQVKVKRHASSANQYKYGKNRAEE 617
V K+ EE + G + SC ++ + ++ K+ AS+ +Y K + EE
Sbjct: 351 VSENKVLREENDLEAGNLHPQQDQSCLKECPCMKGGTDMQTKKEASAETEYM--KQQYEE 408
Query: 618 DARRYLVEKEKLEKEKETIRTELI-----ALRQEKRELKEAIRSSPGAKLKALEEAVATL 672
D R+ K + E+EK+ ++ +L+ +++ E+K ++RSS A+ K L+ V
Sbjct: 409 DLRKI---KHQTEEEKKHLKDQLVKRLEDLVKKHTVEIK-SVRSSVEAERKKLQREVEAQ 464
Query: 673 EAQCRAKEERRI-DLELKLVAVKERLQQSL 701
+ R K E+ I LE + A+ +LQ SL
Sbjct: 465 LEEVRKKSEKEIKQLEEEKAALNVKLQNSL 494
Score = 33.5 bits (75), Expect = 0.76
Identities = 26/110 (23%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 573 PTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKE 632
P GA + C Q V+R + Q++ + D RR+L E ++ ++
Sbjct: 793 PPGAAGQGSGEGCGLWEENAQLQDAVRRLRAEVEQHQQEAQKLR-DQRRFLEETQQAQRA 851
Query: 633 KETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEER 682
+E + LRQE R+ +A+ + + L+ +A LEA+ + E+
Sbjct: 852 RE-----VETLRQEHRKEMQAMVADFSSAQAQLQARLAALEAELKDSGEK 896
Score = 33.1 bits (74), Expect = 1.00
Identities = 29/148 (19%), Positives = 72/148 (48%), Gaps = 7/148 (4%)
Query: 577 QVKRHASSCSEKSHRVDPQVKV--KRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKE 634
+++R ++++H + Q++ +R + ++ + +A E+ R L+ + +
Sbjct: 640 KLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEE-RLKKESSHSLQIQHQ 698
Query: 635 TIRTELIAL----RQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKL 690
T R EL AL RQE +E +E +++ L++L + ++ +A C ++ L+ +L
Sbjct: 699 THRLELQALEEKARQELQEERERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQAEL 758
Query: 691 VAVKERLQQSLAGGPALGLSVSSKPKSG 718
A+ + S G + ++++ + G
Sbjct: 759 RALGRQQASSQCPGDSKDHIIATEERGG 786
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 41.6 bits (96), Expect = 0.003
Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
Query: 575 GAQVKRHASSCSEKSHRVDPQVKVKRHASSA-----NQYKYGKNRAEEDARRYLVEKEKL 629
GA+++ E+ + ++ RH A Q R EE R + EKE L
Sbjct: 675 GAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEAL 734
Query: 630 EKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELK 689
+EK + L A+ +++++L E ++ AK + LE ++ + Q E + LE++
Sbjct: 735 VREKAALEVRLQAVERDRQDLAEQLQGLSSAK-ELLESSLFEAQQQNSVIEVTKGQLEVQ 793
Query: 690 LVAVKE 695
+ V +
Sbjct: 794 IQTVTQ 799
Score = 34.3 bits (77), Expect = 0.45
Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 18/122 (14%)
Query: 595 QVKVKRHASSANQYKYGKNRAE-EDARRYLVEKEKLEKEKE----TIRTELIALRQEKRE 649
Q + R + A Q GK A + ++L+E+ +L + E T++ L A + R+
Sbjct: 1955 QEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQ 2014
Query: 650 LKEAIRSSPG----------AKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQ 699
L+EA+R G ++ L++A+A + + R ++ER LE L +R+Q+
Sbjct: 2015 LEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLA---QRVQE 2071
Query: 700 SL 701
++
Sbjct: 2072 NM 2073
Score = 31.6 bits (70), Expect = 2.9
Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 6/90 (6%)
Query: 604 SANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKR----ELKEAIRSSP- 658
+A Q++ +E++ L +K L+K+ E ++++L+A +R E++E +R +
Sbjct: 983 AARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQE 1042
Query: 659 -GAKLKALEEAVATLEAQCRAKEERRIDLE 687
K LE A+L KE+R + L+
Sbjct: 1043 YNRIQKELEREKASLTLSLMEKEQRLLVLQ 1072
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 41.2 bits (95), Expect = 0.004
Identities = 30/123 (24%), Positives = 63/123 (51%), Gaps = 7/123 (5%)
Query: 562 YEKMQDEEPER--PTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDA 619
Y+KMQ+EEP++ P + KR A+ R + +++ +R A Q + + +A+++
Sbjct: 347 YQKMQEEEPQKKLPVTFEDKRKAN-----YERGNMELEKRRQALMEQQQREAERKAQKEK 401
Query: 620 RRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAK 679
+ ++ +L++++ + EL +++REL+ ++ E A LE Q R +
Sbjct: 402 EEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLE 461
Query: 680 EER 682
ER
Sbjct: 462 WER 464
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 41.2 bits (95), Expect = 0.004
Identities = 30/123 (24%), Positives = 63/123 (51%), Gaps = 7/123 (5%)
Query: 562 YEKMQDEEPER--PTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDA 619
Y+KMQ+EEP++ P + KR A+ R + +++ +R A Q + + +A+++
Sbjct: 347 YQKMQEEEPQKKLPVTFEDKRKAN-----YERGNMELEKRRQALMEQQQREAERKAQKEK 401
Query: 620 RRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAK 679
+ ++ +L++++ + EL +++REL+ ++ E A LE Q R +
Sbjct: 402 EEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLE 461
Query: 680 EER 682
ER
Sbjct: 462 WER 464
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 41.2 bits (95), Expect = 0.004
Identities = 30/123 (24%), Positives = 63/123 (51%), Gaps = 7/123 (5%)
Query: 562 YEKMQDEEPER--PTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDA 619
Y+KMQ+EEP++ P + KR A+ R + +++ +R A Q + + +A+++
Sbjct: 347 YQKMQEEEPQKKLPVTFEDKRKAN-----YERGNMELEKRRQALMEQQQREAERKAQKEK 401
Query: 620 RRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAK 679
+ ++ +L++++ + EL +++REL+ ++ E A LE Q R +
Sbjct: 402 EEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLE 461
Query: 680 EER 682
ER
Sbjct: 462 WER 464
>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
isoform 1 [Homo sapiens]
Length = 632
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/171 (20%), Positives = 71/171 (41%), Gaps = 14/171 (8%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRY 622
E + E P P+ +++ + + QVK + S NQ + + R +E+ R
Sbjct: 293 EPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKNNQRISLLNQRQEERIREQEERLRK 352
Query: 623 LVEK-EKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEE 681
E+ ++ K + + ++ E K A++ ++K L+E + + +++
Sbjct: 353 QEERIQEQHKSLQQLAKPQSVFKEPNNENKNALQLEQ--QVKELQEKLGEEHLEAASQQN 410
Query: 682 RRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQP 732
+++ +L L+A+ P G GE A +P SVPE P
Sbjct: 411 QQLTAQLSLMAL-----------PGEGHGGEHLDSEGEEAPRPMPSVPEDP 450
>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
Length = 508
Score = 40.8 bits (94), Expect = 0.005
Identities = 40/130 (30%), Positives = 58/130 (44%), Gaps = 17/130 (13%)
Query: 616 EEDARRYLVEKEKLEKEKETIRTELIALRQEKRELK---EAIRSSPGAKLKA---LEEAV 669
E R E EK E +T EL+ LR+E+RE E RS G L A L+ V
Sbjct: 217 EAQIRGLREEVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRV 276
Query: 670 ATLEAQCRAKEERRIDLELKLVAVKERLQQSL------AGGPALGLSVSSKPKSGETANK 723
+ LE +E R D ++ +++ L SL G A G + +++ A+
Sbjct: 277 SELE-----EESRLQDADVSAASLQSELAHSLDDGDQGQGADAPGDTPTTRSPKTRKASS 331
Query: 724 PQNSVPEQPL 733
PQ S PE+ L
Sbjct: 332 PQPSPPEEIL 341
>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 40.4 bits (93), Expect = 0.006
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 16/170 (9%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRY 622
E + E P P+ +++ + + QVK +H S N+ + + R E R
Sbjct: 293 EPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQ--EERIREQEERL 350
Query: 623 LVEKEKLEKEKETIRTELIALRQEKRELKEAIRSS--PGAKLKALEEAVATLEAQCRAKE 680
++E+L+++ E +R +L + EL +S+ ++K L+E + + +++
Sbjct: 351 RKQEERLQEQHEKLR-QLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQ 409
Query: 681 ERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPE 730
+++ +L L+A+ P G GE A +P SVPE
Sbjct: 410 NQQLTAQLSLMAL-----------PGEGHGGEHLDSEGEEAPQPMPSVPE 448
>gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 632
Score = 40.4 bits (93), Expect = 0.006
Identities = 34/173 (19%), Positives = 74/173 (42%), Gaps = 18/173 (10%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRY 622
E + E P P+ +++ + + QVK + S NQ + + R +E R
Sbjct: 293 EPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRISLLNQRQ--EERIQEQEERL 350
Query: 623 LVEKEKLEKEKETIRT---ELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAK 679
++E+++++ ++++ + E K A++ ++K L+E + + ++
Sbjct: 351 RKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQ--QVKELQEKLGEEHLEAASQ 408
Query: 680 EERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQP 732
+ +++ +L L+A+ P G GE A +P SVPE P
Sbjct: 409 QNQQLTAQLSLMAL-----------PGEGHGGEHLDSEGEEAPRPMPSVPEDP 450
>gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 4 [Homo sapiens]
Length = 632
Score = 40.4 bits (93), Expect = 0.006
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 16/170 (9%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRY 622
E + E P P+ +++ + + QVK +H S N+ + + R E R
Sbjct: 293 EPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQ--EERIREQEERL 350
Query: 623 LVEKEKLEKEKETIRTELIALRQEKRELKEAIRSS--PGAKLKALEEAVATLEAQCRAKE 680
++E+L+++ E +R +L + EL +S+ ++K L+E + + +++
Sbjct: 351 RKQEERLQEQHEKLR-QLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEEHLEAASQQ 409
Query: 681 ERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPE 730
+++ +L L+A+ P G GE A +P SVPE
Sbjct: 410 NQQLTAQLNLMAL-----------PGEGHGGEHLDSEGEEAPQPMPSVPE 448
>gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-like
protein 1 isoform 1 [Homo sapiens]
Length = 632
Score = 40.4 bits (93), Expect = 0.006
Identities = 45/175 (25%), Positives = 75/175 (42%), Gaps = 22/175 (12%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRY 622
E + E P P+ +++ + + QVK + S NQ R EE R
Sbjct: 293 EPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKNNQRISLLNQ------RQEERIRE- 345
Query: 623 LVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEER 682
++E+L K++E I+ + +L+Q + +++ P + K+ TL+ + + KE +
Sbjct: 346 --QEERLRKQEERIQEQHKSLQQLAKP--QSVFEEPNNENKS------TLQLEQQVKELQ 395
Query: 683 RIDLELKLVAVKERLQQ-----SLAGGPALGLSVSSKPKSGETANKPQNSVPEQP 732
E L A ++ QQ SL P G GE A +P SVPE P
Sbjct: 396 EKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPQPMPSVPEDP 450
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 40.4 bits (93), Expect = 0.006
Identities = 36/154 (23%), Positives = 68/154 (44%), Gaps = 18/154 (11%)
Query: 564 KMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKY------------- 610
K+Q +E R K+ A +E+ + Q+K+ + + +
Sbjct: 906 KLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQIL 965
Query: 611 --GKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEA 668
K + EE A L+E EK KEKE R + + L+ ++RE + A ++A ++A
Sbjct: 966 EAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKA-MEARKKA 1024
Query: 669 VATLEAQCRAKEERRIDLELKLVAVKERLQQSLA 702
+ ++E+R++ E KL + RL+ +A
Sbjct: 1025 EEKERLKQEKRDEKRLNKERKL--EQRRLELEMA 1056
>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
Length = 625
Score = 40.0 bits (92), Expect = 0.008
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 5/101 (4%)
Query: 648 RELKEAIRSSPGAKLKALEEAVATLEAQCRAK-EERRIDLELKLVAVKERLQQSLAGGPA 706
R L + +R +PG ++ EA+ RAK ++ R + + + K RL L+ A
Sbjct: 130 RALADLVREAPGRSMRVATGLYEAYEAERRAKLQQCRAERDRIMREEKRRLFTPLSPAAA 189
Query: 707 LGLSVSSKPKSGETANKPQNSVPEQPLPVNCVSELRKRSPS 747
+ +S P +G +++ S+P P P RK SPS
Sbjct: 190 AAAAAASAPSAGSSSSCSSASLPASPAP----RAARKASPS 226
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 40.0 bits (92), Expect = 0.008
Identities = 48/230 (20%), Positives = 95/230 (41%), Gaps = 26/230 (11%)
Query: 515 VTPEALHYDYVDVETLTSIVSAGRNSFLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPT 574
VTP D E T +++ R R + Q + D ++M++E+ R
Sbjct: 584 VTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERD---KRMREEQLAREA 640
Query: 575 GAQVKRHASSC--SEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKE 632
A+ +R A + E+ R Q + + Q + + R+ E+A R +E+EK ++
Sbjct: 641 EARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQ 700
Query: 633 KETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVA 692
+E R E ++ L+E ++ + +++ ++ + EA + A
Sbjct: 701 QEQERQE------RRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVK------A 748
Query: 693 VKERLQQSLAGGPALGLSVSSKPKSGETANKPQNSVPEQPLPVNCVSELR 742
V+ R + GL + K +PQ S+P + LP + V+ L+
Sbjct: 749 VEAR---------SPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQ 789
Score = 33.1 bits (74), Expect = 1.00
Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 9/77 (11%)
Query: 625 EKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEERRI 684
E+ KL KE+ R + +A K+A+ K KAL E L+ + R EE+R+
Sbjct: 137 ERHKLAKERREERAKYLAA-------KKAVWLEKEEKAKALREK--QLQERRRRLEEQRL 187
Query: 685 DLELKLVAVKERLQQSL 701
E + A++ER +Q L
Sbjct: 188 KAEQRRAALEERQRQKL 204
Score = 32.3 bits (72), Expect = 1.7
Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 573 PTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQ-YKYGKNRAEEDARRYLVEKEKLEK 631
P A+ R +S S + K+ A + +K K R EE A +YL K+ +
Sbjct: 103 PRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERA-KYLAAKKAVWL 161
Query: 632 EKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEER 682
EKE + ALR+ ++L+E R +LKA E+ A LE + R K E+
Sbjct: 162 EKE---EKAKALRE--KQLQERRRRLEEQRLKA-EQRRAALEERQRQKLEK 206
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 39.7 bits (91), Expect = 0.011
Identities = 29/138 (21%), Positives = 67/138 (48%), Gaps = 15/138 (10%)
Query: 563 EKMQDEEPE-RPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARR 621
EKM D+E + R +V R E+ ++ Q + R Q + K +E+ +
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE--K 621
Query: 622 YLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEE 681
++EK+++++E +R + +R+++++++E EE + E + +EE
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ------------EEKIREQEEMMQEQEE 669
Query: 682 RRIDLELKLVAVKERLQQ 699
+ + E K+ +E++Q+
Sbjct: 670 KMWEQEEKMCEQEEKMQE 687
Score = 35.4 bits (80), Expect = 0.20
Identities = 28/130 (21%), Positives = 59/130 (45%)
Query: 570 PERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKL 629
P++ A+ S ++ QV+ + NQ + K +E+ + EK +
Sbjct: 320 PQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 379
Query: 630 EKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEERRIDLELK 689
++EK + E I ++EK +E + K++ EE + E + R +EE + E K
Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439
Query: 690 LVAVKERLQQ 699
+ ++E++ +
Sbjct: 440 IRELEEKMHE 449
Score = 34.3 bits (77), Expect = 0.45
Identities = 33/139 (23%), Positives = 69/139 (49%), Gaps = 8/139 (5%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRY 622
EK++++E + A++ R E+ ++ Q + K ++ K R EE +
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE-KMWRQEEKIHEQEKIREEEKRQ-- 520
Query: 623 LVEKEKLEKEKETIRTELIALRQEKR--ELKEAIRSSPGAKLKALEEAVATLEAQCRAKE 680
E+E++ +++E IR + RQ+++ E +E IR K+ EE + E + R +E
Sbjct: 521 --EQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE-EKMWRQEEKMHDQEEKIREQE 577
Query: 681 ERRIDLELKLVAVKERLQQ 699
E+ E K+ +E++++
Sbjct: 578 EKVWRQEEKIREQEEKIRE 596
Score = 33.9 bits (76), Expect = 0.58
Identities = 29/138 (21%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 563 EKMQDEEPE-RPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARR 621
EK++++E + R +++ E+ ++ Q + Q + K R +E+ R
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Query: 622 YLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCRAKEE 681
+K + ++EK + E++ ++EK +E K+ EE + E + R +EE
Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQE-------EKMCEQEEKMQEQEEKMRRQEE 697
Query: 682 RRIDLELKLVAVKERLQQ 699
+ + E++L +E++Q+
Sbjct: 698 KMWEQEVRLRQQEEKMQE 715
Score = 32.3 bits (72), Expect = 1.7
Identities = 31/140 (22%), Positives = 67/140 (47%), Gaps = 9/140 (6%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRY 622
EK+ ++E R + ++ + ++ Q ++ R ++ + + EE R
Sbjct: 505 EKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWR- 561
Query: 623 LVEKEKLEKEKETIRT--ELIALRQEK-RELKEAIRSSPGAKLKALEEAVATLEAQCRAK 679
++EK+ ++E IR E + ++EK RE +E IR K++ EE E + +
Sbjct: 562 --QEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE-EKIREQEEMTQEQEEKMGEQ 618
Query: 680 EERRIDLELKLVAVKERLQQ 699
EE+ + E K+ +E++++
Sbjct: 619 EEKMCEQEEKMQEQEEKMRR 638
Score = 32.0 bits (71), Expect = 2.2
Identities = 27/143 (18%), Positives = 68/143 (47%), Gaps = 8/143 (5%)
Query: 563 EKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASSANQYKY---GKNRAEEDA 619
EK++++E E+ + K H + + Q ++ R + + K + E
Sbjct: 491 EKIREQE-EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549
Query: 620 RRYLVEKEKLEKEKETIRTELIALRQEKREL---KEAIRSSPGAKLKALEEAVATLEAQC 676
+ ++EK+ +++E + + +R+++ ++ +E IR K++ EE + E
Sbjct: 550 EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE-EKIREQEEKIREQEEMT 608
Query: 677 RAKEERRIDLELKLVAVKERLQQ 699
+ +EE+ + E K+ +E++Q+
Sbjct: 609 QEQEEKMGEQEEKMCEQEEKMQE 631
Score = 31.2 bits (69), Expect = 3.8
Identities = 26/125 (20%), Positives = 57/125 (45%), Gaps = 5/125 (4%)
Query: 563 EKMQDEEPE-RPTGAQVKRHASSCSEKSHRVDPQVKV----KRHASSANQYKYGKNRAEE 617
EK++++E + R +++R EK ++ Q ++ + + + K
Sbjct: 382 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 441
Query: 618 DARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKALEEAVATLEAQCR 677
+ + E+EK+ +++E + E QEKR+ +EA K++ EE + E +
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 678 AKEER 682
+EE+
Sbjct: 502 RQEEK 506
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,500,221
Number of Sequences: 37866
Number of extensions: 1690333
Number of successful extensions: 10550
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 478
Number of HSP's that attempted gapping in prelim test: 8681
Number of HSP's gapped (non-prelim): 2047
length of query: 768
length of database: 18,247,518
effective HSP length: 110
effective length of query: 658
effective length of database: 14,082,258
effective search space: 9266125764
effective search space used: 9266125764
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.