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Search of human proteins with 5454156
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5454156 ubiquitin specific protease 16 isoform a [Homo
sapiens]
(823 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens] 1673 0.0
gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens] 1673 0.0
gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens] 1667 0.0
gi|122937412 ubiquitin specific peptidase 45 [Homo sapiens] 552 e-157
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 134 3e-31
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 100 9e-21
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 96 1e-19
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 91 6e-18
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 90 7e-18
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 90 7e-18
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 90 7e-18
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 89 2e-17
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 88 4e-17
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 87 5e-17
gi|57529246 ubiquitin thioesterase 19 [Homo sapiens] 87 8e-17
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 87 8e-17
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 86 1e-16
gi|22550104 ubiquitin specific protease 32 [Homo sapiens] 86 1e-16
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 86 2e-16
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 86 2e-16
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 86 2e-16
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 85 2e-16
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 84 7e-16
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 82 2e-15
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 82 2e-15
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 80 8e-15
gi|183397136 ubiquitin specific protease 20 [Homo sapiens] 80 8e-15
gi|183397134 ubiquitin specific protease 20 [Homo sapiens] 80 8e-15
gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo ... 80 8e-15
gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo ... 80 8e-15
>gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 1673 bits (4332), Expect = 0.0
Identities = 823/823 (100%), Positives = 823/823 (100%)
Query: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK
Sbjct: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
Query: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD
Sbjct: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
Query: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENM 180
NEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENM
Sbjct: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENM 180
Query: 181 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 240
AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD
Sbjct: 181 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 240
Query: 241 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 300
LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS
Sbjct: 241 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 300
Query: 301 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 360
QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG
Sbjct: 301 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 360
Query: 361 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 420
GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD
Sbjct: 361 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 420
Query: 421 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 480
NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE
Sbjct: 421 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 480
Query: 481 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 540
YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI
Sbjct: 481 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 540
Query: 541 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 600
NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT
Sbjct: 541 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 600
Query: 601 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 660
PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR
Sbjct: 601 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 660
Query: 661 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 720
QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL
Sbjct: 661 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 720
Query: 721 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 780
DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD
Sbjct: 721 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 780
Query: 781 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL
Sbjct: 781 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
>gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 1673 bits (4332), Expect = 0.0
Identities = 823/823 (100%), Positives = 823/823 (100%)
Query: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK
Sbjct: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
Query: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD
Sbjct: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
Query: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENM 180
NEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENM
Sbjct: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENM 180
Query: 181 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 240
AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD
Sbjct: 181 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 240
Query: 241 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 300
LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS
Sbjct: 241 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 300
Query: 301 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 360
QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG
Sbjct: 301 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 360
Query: 361 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 420
GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD
Sbjct: 361 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 420
Query: 421 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 480
NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE
Sbjct: 421 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 480
Query: 481 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 540
YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI
Sbjct: 481 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 540
Query: 541 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 600
NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT
Sbjct: 541 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 600
Query: 601 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 660
PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR
Sbjct: 601 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 660
Query: 661 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 720
QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL
Sbjct: 661 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 720
Query: 721 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 780
DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD
Sbjct: 721 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 780
Query: 781 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL
Sbjct: 781 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
>gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens]
Length = 822
Score = 1667 bits (4316), Expect = 0.0
Identities = 822/823 (99%), Positives = 822/823 (99%), Gaps = 1/823 (0%)
Query: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK
Sbjct: 1 MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
Query: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD
Sbjct: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
Query: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENM 180
NEVQYCSSNQLGQVVDYVRKQASITTPKP EKDNGNIELENKKLEKESKNEQEREKKENM
Sbjct: 121 NEVQYCSSNQLGQVVDYVRKQASITTPKP-EKDNGNIELENKKLEKESKNEQEREKKENM 179
Query: 181 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 240
AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD
Sbjct: 180 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 239
Query: 241 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 300
LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS
Sbjct: 240 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 299
Query: 301 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 360
QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG
Sbjct: 300 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 359
Query: 361 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 420
GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD
Sbjct: 360 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKD 419
Query: 421 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 480
NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE
Sbjct: 420 NDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSE 479
Query: 481 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 540
YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI
Sbjct: 480 YEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNI 539
Query: 541 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 600
NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT
Sbjct: 540 NMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHT 599
Query: 601 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 660
PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR
Sbjct: 600 PGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRR 659
Query: 661 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 720
QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL
Sbjct: 660 QCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEIL 719
Query: 721 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 780
DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD
Sbjct: 720 DLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGD 779
Query: 781 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL
Sbjct: 780 IPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 822
>gi|122937412 ubiquitin specific peptidase 45 [Homo sapiens]
Length = 814
Score = 552 bits (1423), Expect = e-157
Identities = 318/835 (38%), Positives = 479/835 (57%), Gaps = 50/835 (5%)
Query: 4 KRTKGKTVPID-DSSETLEP--VCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
KR+K TVP D DSS+ + C+H+ + ++K+A+ W++C +C + + D
Sbjct: 15 KRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWSVCSECLKERRFYDG 74
Query: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
T + +WLCLKCG QGCG+NS+ QH+LKH+ + R+EPHC++++L W +WCY CD
Sbjct: 75 QLVLTSD---IWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECD 131
Query: 121 NEVQ-YCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKEN 179
++ +C+ L Q+VD+++K AS T + + K +E+ + +
Sbjct: 132 EKLSTHCNKKVLAQIVDFLQKHASKT--------------QTSAFSRIMKLCEEKCETDE 177
Query: 180 MAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPP 239
+ K N ++V+G++NLGNTCFFNAVMQNL+QT L +L+ E+K S T +KI P
Sbjct: 178 IQKGGKCRN----LSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPS 233
Query: 240 DLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQD 299
+ +PL + L PGPLT A+ FL+ M+ET+KG ++PK LF+Q+C+KA RFK +QQQD
Sbjct: 234 SDSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQD 293
Query: 300 SQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEK-LDEELKNKVKDYEKKKSMPSFVDRI 358
SQELL YLLD +R EE +R+ ILKAF N T K D+E + KVK Y K+ +F+DRI
Sbjct: 294 SQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRI 353
Query: 359 FGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSV-NDKNLKKTVEDEDQDSEE 417
F GELTS +MC++C +S V + F+D+SLP+++++ K + N +++ + D D
Sbjct: 354 FIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD--- 410
Query: 418 EKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPE 477
+ + + E P KH K K Q K R+ + N+ + + +
Sbjct: 411 -RYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEM-NGD 468
Query: 478 DSEYEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDM 537
+ + M+ + +N S++ H E + D + + ES +
Sbjct: 469 SLMFASLMNSESRLNESPTDDSEKEASHSE---SNVDADSEPSESESASKQTGLFRSSSG 525
Query: 538 KNINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDE----INIE 593
+ D L L++ Y E +G+ +++ L L++ + D+ N
Sbjct: 526 SGVQPDGPLYPLSAGKL-----LYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQP 580
Query: 594 ILNDSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLL 653
+ ++ + + + P+ AF TL+ + + ECSIQ CLYQFT E L NKLL
Sbjct: 581 LNISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLL 640
Query: 654 CEVCTRRQCNGPKANIKGERK--HVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVN 711
CE CT+ + + E+K VYTNA+KQ+LIS P VL LHLKRF QAG +LRKVN
Sbjct: 641 CENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVN 700
Query: 712 KHIKFPEILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSH 771
+H+ FP +LDLAPFC+ CKN A +VLY LYG+VEHSG+MR GHYTAY K RT +
Sbjct: 701 RHVDFPLMLDLAPFCSATCKN-ASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRK 759
Query: 772 LS-NLVLHGDIP--QDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
LS + ++P + + ES GQW H+SDT++Q VP ++ L++QAYLLFYER+L
Sbjct: 760 LSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL 814
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 134 bits (337), Expect = 3e-31
Identities = 178/829 (21%), Positives = 313/829 (37%), Gaps = 160/829 (19%)
Query: 8 GKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEE 67
GK I + C H+ E K+ L+ CQDCK
Sbjct: 23 GKQEKIPNKMSAFRNHCPHLDSVGEI--TKEDLIQKSLGTCQDCKVQG------------ 68
Query: 68 KPSVWLCL--KCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQY 125
P++W CL +C + GCG SQ H+ H + H L ++L VWCY C EV
Sbjct: 69 -PNLWACLENRCSYVGCGE-SQVDHSTIH---SQETKHYLTVNLTTLRVWCYACSKEVFL 123
Query: 126 CSSNQLGQVVDYVRKQASITTPKPAE-KDNGNIELENKKLEKESKNEQEREKKENMAKEN 184
+ +VR+ I + K N L+ + + E ++++ +
Sbjct: 124 DRKLGTQPSLPHVRQPHQIQENSVQDFKIPSNTTLKTPLVAVFDDLDIEADEEDELRARG 183
Query: 185 PPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALT 244
+ GL N+GNTC+ NA +Q LS P L + ++ LA T
Sbjct: 184 ----------LTGLKNIGNTCYMNAALQALSNCPPLTQFF-----------LDCGGLART 222
Query: 245 EPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELL 304
+ + P + +++ G V P LF + F+GY QQD+QE L
Sbjct: 223 D------KKPAICKSYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFL 276
Query: 305 RYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELT 364
R L+D L EELK +V + E+ + + + +
Sbjct: 277 RCLMD-----------------------LLHEELKEQVMEVEEDPQTITTEETMEEDKSQ 313
Query: 365 SMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKDNDSY 424
S + C + S + ++++G + ++ N + T+ +D ++ E D
Sbjct: 314 SDVDFQSCESCSNSDRA---------ENENGSRCFSEDNNETTMLIQDDENNSEMSKDWQ 364
Query: 425 IKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSEYEAE 484
++ + + + + + + + + Q+ ++ ++ H SEY +
Sbjct: 365 KEKMCNKINKVNSEGEFDKDRDSISETVDLNNQETVKVQI----------HSRASEYITD 414
Query: 485 MSLQGEVNIKSNHISQEGVMHKEYCVNQKDLN---GQA---KMIESVTDNQKSTEEVDMK 538
+ +++ S EGV + K N G A K +S + +K +
Sbjct: 415 VH-SNDLSTPQILPSNEGVNPRLSASPPKSGNLWPGLAPPHKKAQSASPKRKKQHKKYRS 473
Query: 539 NINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKN--LNLNAALHPDEI-NIEIL 595
I+ D +++S + +T + ++ + K L+++ HP I
Sbjct: 474 VISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVKAGSC 533
Query: 596 NDSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCE 655
+++ P + AF + F ++Q CL F ++L+ N CE
Sbjct: 534 GEAYAPQGWI----------AFFMEYVKSWFWGPVVTLQDCLAAFFARDELKGDNMYSCE 583
Query: 656 VCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIK 715
C + + N K + P +L +HLKRF+ K++ H+
Sbjct: 584 KCKKLR-----------------NGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVS 626
Query: 716 FP-EILDLAPFCTLKCKNVAEENTR--VLYSLYGVVEHSGTMRSGHYTAYAKARTANSHL 772
FP E LDL PF +A+++ V Y L V+ H GT SGHY AY + ++L
Sbjct: 627 FPLEGLDLQPF-------LAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCR-----NNL 674
Query: 773 SNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYER 821
+NL W+ D V V + V N++AY+LFY +
Sbjct: 675 NNL-----------------WYEFDDQSVTEVSESTVQNAEAYVLFYRK 706
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 99.8 bits (247), Expect = 9e-21
Identities = 99/352 (28%), Positives = 144/352 (40%), Gaps = 48/352 (13%)
Query: 70 SVWLCLKCGHQGCGRNSQEQHALKHY------LTPRSEP-------HCLVLSLDNWSVWC 116
S W+CL C CGR HA KHY LT + H + + ++S +C
Sbjct: 37 SPWVCLTCSSVHCGRYVNG-HAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYC 95
Query: 117 YVCDNEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREK 176
Y CD+ V + +LG +V VR+ +N + K K +N K
Sbjct: 96 YRCDDFV--VNDTKLG-LVQKVREHLQ-------NLENSAFTADRHKKRKLLENSTLNSK 145
Query: 177 KENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKI 236
+ K N S I GL NLGNTCF NA++Q+LS KE+ V++
Sbjct: 146 ---LLKVN---GSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPA----VEL 195
Query: 237 EPPDLALTEPLEINLEPPGPLTLA--MSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKG 294
A + ++L + L + + + +P+ LF V K F+G
Sbjct: 196 RNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRG 255
Query: 295 YQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKK---KSM 351
YQQQD+ E +RYLLD + E L+ N + +N K
Sbjct: 256 YQQQDAHEFMRYLLDHLHLE---------LQGGFNGVSRSAILQENSTLSASNKCCINGA 306
Query: 352 PSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKN 403
+ V IFGG L + + C C T S + FLDLSL + K+S N +N
Sbjct: 307 STVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQEN 358
Score = 80.9 bits (198), Expect = 5e-15
Identities = 62/213 (29%), Positives = 93/213 (43%), Gaps = 52/213 (24%)
Query: 612 DPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKG 671
D + F + ++ N CS++ CL FT E+L + +C C ++Q
Sbjct: 343 DIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQ---------- 392
Query: 672 ERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKC 730
+ K+ I P VL LHLKRF + KV+ +++FP LD +KC
Sbjct: 393 -------KSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLD------MKC 439
Query: 731 KNVAEENT---RVLYSLYGVVEHSGT-MRSGHYTAYAKARTANSHLSNLVLHGDIPQDFE 786
+ EN+ LY L VV H G+ + SGHYTAYA
Sbjct: 440 YLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYA----------------------- 476
Query: 787 MESKGQWFHISDTHVQAVPTTKVLNSQAYLLFY 819
+G+WFH +D+ V V+ ++AY+LFY
Sbjct: 477 -THEGRWFHFNDSTVTLTDEETVVKAKAYILFY 508
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 95.9 bits (237), Expect = 1e-19
Identities = 64/193 (33%), Positives = 99/193 (51%), Gaps = 14/193 (7%)
Query: 197 GLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGP 256
GLSNLGNTCF N+ +Q LS TP L E K +L PL + G
Sbjct: 261 GLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQ--------EELNFDNPLGMR----GE 308
Query: 257 LTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEH 316
+ + ++ + +M K VTP+ +QV + A +F GYQQQD QELL +LLDG+ E+
Sbjct: 309 IAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLH-EDL 367
Query: 317 QRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVS 376
R+ K ++ + D+ + + + K++ VD IF G S ++C +C +S
Sbjct: 368 NRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVD-IFHGLFKSTLVCPECAKIS 426
Query: 377 LVHESFLDLSLPV 389
+ + F L+LP+
Sbjct: 427 VTFDPFCYLTLPL 439
Score = 67.4 bits (163), Expect = 5e-11
Identities = 49/190 (25%), Positives = 78/190 (41%), Gaps = 46/190 (24%)
Query: 633 IQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPV 692
++ C+ FT EKL + C C Q A K++ + PPV
Sbjct: 759 LKDCIELFTTKEKLGAEDPWYCPNCKEHQ-----------------QATKKLDLWSLPPV 801
Query: 693 LTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHS 751
L +HLKRF + + K++ + FP LD++ F + Y+L V H
Sbjct: 802 LVVHLKRFSYSRYMRDKLDTLVDFPINDLDMSEFL------INPNAGPCRYNLIAVSNHY 855
Query: 752 GTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVLN 811
G M GHYTA+AK + G+W++ D+ V ++++
Sbjct: 856 GGMGGGHYTAFAKNK----------------------DDGKWYYFDDSSVSTASEDQIVS 893
Query: 812 SQAYLLFYER 821
AY+LFY+R
Sbjct: 894 KAAYVLFYQR 903
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 90.5 bits (223), Expect = 6e-18
Identities = 104/431 (24%), Positives = 167/431 (38%), Gaps = 66/431 (15%)
Query: 8 GKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEE 67
GK I + C H+ E K+ L+ CQDCK
Sbjct: 23 GKQEKIPNKMSAFRNHCPHLDSVGEI--TKEDLIQKSLGTCQDCKVQG------------ 68
Query: 68 KPSVWLCL--KCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQY 125
P++W CL +C + GCG SQ H+ H + H L ++L VWCY C EV
Sbjct: 69 -PNLWACLENRCSYVGCGE-SQVDHSTIH---SQETKHYLTVNLTTLRVWCYACSKEVFL 123
Query: 126 CSSNQLGQVVDYVRKQASITTPKPAE-KDNGNIELENKKLEKESKNEQEREKKENMAKEN 184
+ +VR+ I + K N L+ + + E ++++ +
Sbjct: 124 DRKLGTQPSLPHVRQPHQIQENSVQDFKIPSNTTLKTPLVAVFDDLDIEADEEDELRARG 183
Query: 185 PPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALT 244
+ GL N+GNTC+ NA +Q LS P L + ++ LA T
Sbjct: 184 ----------LTGLKNIGNTCYMNAALQALSNCPPLTQFF-----------LDCGGLART 222
Query: 245 EPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELL 304
+ + P + +++ G V P LF + F+GY QQD+QE L
Sbjct: 223 D------KKPAICKSYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFL 276
Query: 305 RYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVK-DYEKKKSMPSFVDRIFGGEL 363
R L+D + E ++V + +TE+ EE K++ D++ +S S DR
Sbjct: 277 RCLMDLLHEELKEQVMEVEEDPQTITTEETMEEDKSQSDVDFQSCESC-SNSDRAENENG 335
Query: 364 TSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKK---TVEDEDQDSEEEKD 420
+ D T L+ DD++ + D +K + + + E +KD
Sbjct: 336 SRCFSEDNNETTMLIQ-----------DDENNSEMSKDWQKEKMCNKINKVNSEGEFDKD 384
Query: 421 NDSYIKERSDI 431
DS I E D+
Sbjct: 385 RDS-ISETVDL 394
Score = 75.1 bits (183), Expect = 2e-13
Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 49/193 (25%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
++Q CL F ++L+ N CE C + + N K + P
Sbjct: 568 TLQDCLAAFFARDELKGDNMYSCEKCKKLR-----------------NGVKFCKVQNFPE 610
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTR--VLYSLYGVV 748
+L +HLKRF+ K++ H+ FP E LDL PF +A+++ V Y L V+
Sbjct: 611 ILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPF-------LAKDSPAQIVTYDLLSVI 663
Query: 749 EHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTK 808
H GT SGHY AY + ++L+NL W+ D V V +
Sbjct: 664 CHHGTASSGHYIAYCR-----NNLNNL-----------------WYEFDDQSVTEVSEST 701
Query: 809 VLNSQAYLLFYER 821
V N++AY+LFY +
Sbjct: 702 VQNAEAYVLFYRK 714
Score = 36.6 bits (83), Expect = 0.097
Identities = 18/47 (38%), Positives = 26/47 (55%)
Query: 343 KDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 389
K ++ K S + IF G + S + C C VS+ E+F DLSLP+
Sbjct: 463 KRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPI 509
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 90.1 bits (222), Expect = 7e-18
Identities = 98/402 (24%), Positives = 159/402 (39%), Gaps = 64/402 (15%)
Query: 37 KKALVNVEWNICQDCKTDNKVKDKAEEETEEKPSVWLCL--KCGHQGCGRNSQEQHALKH 94
K+ L+ CQDCK P++W CL +C + GCG SQ H+ H
Sbjct: 19 KEDLIQKSLGTCQDCKVQG-------------PNLWACLENRCSYVGCGE-SQVDHSTIH 64
Query: 95 YLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQVVDYVRKQASITTPKPAE-KD 153
+ H L ++L VWCY C EV + +VR+ I + K
Sbjct: 65 ---SQETKHYLTVNLTTLRVWCYACSKEVFLDRKLGTQPSLPHVRQPHQIQENSVQDFKI 121
Query: 154 NGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQN 213
N L+ + + E ++++ + + GL N+GNTC+ NA +Q
Sbjct: 122 PSNTTLKTPLVAVFDDLDIEADEEDELRARG----------LTGLKNIGNTCYMNAALQA 171
Query: 214 LSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKK 273
LS P L + ++ LA T+ + P + +++
Sbjct: 172 LSNCPPLTQFF-----------LDCGGLARTD------KKPAICKSYLKLMTELWHKSRP 214
Query: 274 GVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEK 333
G V P LF + F+GY QQD+QE LR L+D + E ++V + +TE+
Sbjct: 215 GSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKEQVMEVEEDPQTITTEE 274
Query: 334 LDEELKNKVK-DYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDD 392
EE K++ D++ +S S DR + D T L+ DD
Sbjct: 275 TMEEDKSQSDVDFQSCESC-SNSDRAENENGSRCFSEDNNETTMLIQ-----------DD 322
Query: 393 QSGKKSVNDKNLKK---TVEDEDQDSEEEKDNDSYIKERSDI 431
++ + D +K + + + E +KD DS I E D+
Sbjct: 323 ENNSEMSKDWQKEKMCNKINKVNSEGEFDKDRDS-ISETVDL 363
Score = 75.1 bits (183), Expect = 2e-13
Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 49/193 (25%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
++Q CL F ++L+ N CE C + + N K + P
Sbjct: 537 TLQDCLAAFFARDELKGDNMYSCEKCKKLR-----------------NGVKFCKVQNFPE 579
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTR--VLYSLYGVV 748
+L +HLKRF+ K++ H+ FP E LDL PF +A+++ V Y L V+
Sbjct: 580 ILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPF-------LAKDSPAQIVTYDLLSVI 632
Query: 749 EHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTK 808
H GT SGHY AY + ++L+NL W+ D V V +
Sbjct: 633 CHHGTASSGHYIAYCR-----NNLNNL-----------------WYEFDDQSVTEVSEST 670
Query: 809 VLNSQAYLLFYER 821
V N++AY+LFY +
Sbjct: 671 VQNAEAYVLFYRK 683
Score = 36.6 bits (83), Expect = 0.097
Identities = 18/47 (38%), Positives = 26/47 (55%)
Query: 343 KDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 389
K ++ K S + IF G + S + C C VS+ E+F DLSLP+
Sbjct: 432 KRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPI 478
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 90.1 bits (222), Expect = 7e-18
Identities = 63/204 (30%), Positives = 100/204 (49%), Gaps = 14/204 (6%)
Query: 186 PMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTE 245
P +S Q + GL NLGNTCF N+ +Q LS T L + + + I + P
Sbjct: 292 PPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNP------- 344
Query: 246 PLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLR 305
L G + A ++ + +M + V P+ +QV + A +F GYQQQDSQELL
Sbjct: 345 -----LGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLA 399
Query: 306 YLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTS 365
+LLDG+ E+ RV K ++ + D + + + + ++ VD F G S
Sbjct: 400 FLLDGLH-EDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVD-TFHGLFKS 457
Query: 366 MIMCDQCRTVSLVHESFLDLSLPV 389
++C +C VS+ + F L+LP+
Sbjct: 458 TLVCPECAKVSVTFDPFCYLTLPL 481
Score = 63.9 bits (154), Expect = 6e-10
Identities = 48/192 (25%), Positives = 80/192 (41%), Gaps = 48/192 (25%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
+++ C+ FT E L + + C C + Q A K+ + P
Sbjct: 777 ALRDCIELFTTMETLGEHDPWYCPNCKKHQ-----------------QATKKFDLWSLPK 819
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPF-CTLKCKNVAEENTRVLYSLYGVVE 749
+L +HLKRF + K++ ++FP L+++ F C L + +Y L V
Sbjct: 820 ILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPY-------VYDLIAVSN 872
Query: 750 HSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKV 809
H G M GHYTAYAK + G+W++ D++V ++
Sbjct: 873 HYGAMGVGHYTAYAKNKL----------------------NGKWYYFDDSNVSLASEDQI 910
Query: 810 LNSQAYLLFYER 821
+ AY+LFY+R
Sbjct: 911 VTKAAYVLFYQR 922
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 90.1 bits (222), Expect = 7e-18
Identities = 63/204 (30%), Positives = 100/204 (49%), Gaps = 14/204 (6%)
Query: 186 PMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTE 245
P +S Q + GL NLGNTCF N+ +Q LS T L + + + I + P
Sbjct: 245 PPSSHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNP------- 297
Query: 246 PLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLR 305
L G + A ++ + +M + V P+ +QV + A +F GYQQQDSQELL
Sbjct: 298 -----LGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLA 352
Query: 306 YLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTS 365
+LLDG+ E+ RV K ++ + D + + + + ++ VD F G S
Sbjct: 353 FLLDGLH-EDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVD-TFHGLFKS 410
Query: 366 MIMCDQCRTVSLVHESFLDLSLPV 389
++C +C VS+ + F L+LP+
Sbjct: 411 TLVCPECAKVSVTFDPFCYLTLPL 434
Score = 63.9 bits (154), Expect = 6e-10
Identities = 48/192 (25%), Positives = 80/192 (41%), Gaps = 48/192 (25%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
+++ C+ FT E L + + C C + Q A K+ + P
Sbjct: 730 ALRDCIELFTTMETLGEHDPWYCPNCKKHQ-----------------QATKKFDLWSLPK 772
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPF-CTLKCKNVAEENTRVLYSLYGVVE 749
+L +HLKRF + K++ ++FP L+++ F C L + +Y L V
Sbjct: 773 ILVVHLKRFSYNRYWRDKLDTVVEFPIRGLNMSEFVCNLSARPY-------VYDLIAVSN 825
Query: 750 HSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKV 809
H G M GHYTAYAK + G+W++ D++V ++
Sbjct: 826 HYGAMGVGHYTAYAKNKL----------------------NGKWYYFDDSNVSLASEDQI 863
Query: 810 LNSQAYLLFYER 821
+ AY+LFY+R
Sbjct: 864 VTKAAYVLFYQR 875
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 88.6 bits (218), Expect = 2e-17
Identities = 66/205 (32%), Positives = 100/205 (48%), Gaps = 19/205 (9%)
Query: 187 MNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEP 246
MNS + GL NLGNTCF N+++Q LS T LR+ + + AL E
Sbjct: 258 MNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEE 317
Query: 247 LEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRY 306
++ T+ S + VV+P E +Q+ + A RF GY QQD+QE LR+
Sbjct: 318 FAKLIQ-----TIWTS--------SPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRF 364
Query: 307 LLDGMRAEEHQRVSKGILKAFGN--STEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELT 364
LLDG+ H V++ L+ N + + L ++ K + + + S + +F G+L
Sbjct: 365 LLDGL----HNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLK 420
Query: 365 SMIMCDQCRTVSLVHESFLDLSLPV 389
S + C C S V + F DLSLP+
Sbjct: 421 SSLTCTDCGYCSTVFDPFWDLSLPI 445
Score = 78.6 bits (192), Expect = 2e-14
Identities = 60/193 (31%), Positives = 83/193 (43%), Gaps = 49/193 (25%)
Query: 630 ECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLA 689
E ++ C+ FT+ + L K C C +C G K IK + I
Sbjct: 452 EVTLMDCMRLFTKEDVLDGDEKPTC--C---RCRGRKRCIK------------KFSIQRF 494
Query: 690 PPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTR-VLYSLYGV 747
P +L LHLKRF ++ K+ + FP LDL F A ENT +Y+LY V
Sbjct: 495 PKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREF--------ASENTNHAVYNLYAV 546
Query: 748 VEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTT 807
HSGT GHYTAY ++ G+W +D+ V + ++
Sbjct: 547 SNHSGTTMGGHYTAYCRS----------------------PGTGEWHTFNDSSVTPMSSS 584
Query: 808 KVLNSQAYLLFYE 820
+V S AYLLFYE
Sbjct: 585 QVRTSDAYLLFYE 597
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 87.8 bits (216), Expect = 4e-17
Identities = 66/208 (31%), Positives = 100/208 (48%), Gaps = 19/208 (9%)
Query: 184 NPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLAL 243
N NS + GL NLGNTCF N+++Q LS T LR+ + + AL
Sbjct: 46 NKAKNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTAL 105
Query: 244 TEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQEL 303
E ++ T+ S + VV+P E +Q+ + A RF GY QQD+QE
Sbjct: 106 VEEFAKLIQ-----TIWTS--------SPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEF 152
Query: 304 LRYLLDGMRAEEHQRVSKGILKAFGN--STEKLDEELKNKVKDYEKKKSMPSFVDRIFGG 361
LR+LLDG+ H V++ L+ N + + L ++ K + + + S + +F G
Sbjct: 153 LRFLLDGL----HNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVG 208
Query: 362 ELTSMIMCDQCRTVSLVHESFLDLSLPV 389
+L S + C C S V + F DLSLP+
Sbjct: 209 QLKSSLTCTDCGYCSTVFDPFWDLSLPI 236
Score = 78.6 bits (192), Expect = 2e-14
Identities = 60/193 (31%), Positives = 83/193 (43%), Gaps = 49/193 (25%)
Query: 630 ECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLA 689
E ++ C+ FT+ + L K C C +C G K IK + I
Sbjct: 243 EVTLMDCMRLFTKEDVLDGDEKPTC--C---RCRGRKRCIK------------KFSIQRF 285
Query: 690 PPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTR-VLYSLYGV 747
P +L LHLKRF ++ K+ + FP LDL F A ENT +Y+LY V
Sbjct: 286 PKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREF--------ASENTNHAVYNLYAV 337
Query: 748 VEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTT 807
HSGT GHYTAY ++ G+W +D+ V + ++
Sbjct: 338 SNHSGTTMGGHYTAYCRS----------------------PGTGEWHTFNDSSVTPMSSS 375
Query: 808 KVLNSQAYLLFYE 820
+V S AYLLFYE
Sbjct: 376 QVRTSDAYLLFYE 388
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 87.4 bits (215), Expect = 5e-17
Identities = 62/220 (28%), Positives = 91/220 (41%), Gaps = 49/220 (22%)
Query: 610 NEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANI 669
+++PE A T++ R+ S+ CL FTR E L + K+ C C
Sbjct: 527 SQNPERADSTVS-RDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQS---------- 575
Query: 670 KGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLK 729
Y + KQ+ + P V HLKRF+ G RK+N I FP LD+ PF
Sbjct: 576 -------YQESTKQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPLELDMTPFLAST 628
Query: 730 CKNVAEEN--------TRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDI 781
++ +E YSL+ V+ H GT+ SGHYT++ +
Sbjct: 629 KESRMKEGQPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIR----------------- 671
Query: 782 PQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYER 821
+ K QWF D + +L S+ YLLFY +
Sbjct: 672 ------QQKDQWFSCDDAIITKATIEDLLYSEGYLLFYHK 705
Score = 80.1 bits (196), Expect = 8e-15
Identities = 82/340 (24%), Positives = 134/340 (39%), Gaps = 48/340 (14%)
Query: 74 CLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLG- 132
CL C GC E+H KH T + H L + L + ++C++C + V Q+
Sbjct: 249 CLSCVFFGC---FTEKHIHKHAETKQ---HHLAVDLYHGVIYCFMCKDYVYDKDIEQIAK 302
Query: 133 QVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQ 192
+ + + + + T+ + + E+K+ E+K E+E K K+ S
Sbjct: 303 ETKEKILRLLTSTSTDVSHQQFMTSGFEDKQSTCETK---EQEPKLVKPKKKRRKKSVYT 359
Query: 193 ITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLE 252
+ ++GL NLGNTCF N ++Q L+ P+L++ K I
Sbjct: 360 VGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKC-----------------IMTS 402
Query: 253 PPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMR 312
P L MS + M + P +L + A GY+QQD+ E L +LD +
Sbjct: 403 PSLCLVCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVL- 461
Query: 313 AEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQC 372
H + G +E N +D+IF G L S + C C
Sbjct: 462 -HRHSKDDSG------------GQEANN-------PNCCNCIIDQIFTGGLQSDVTCQAC 501
Query: 373 RTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDED 412
+VS + D+SL + + S N + TV +D
Sbjct: 502 HSVSTTIDPCWDISLDLPGSCATFDSQNPERADSTVSRDD 541
>gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]
Length = 1318
Score = 86.7 bits (213), Expect = 8e-17
Identities = 65/227 (28%), Positives = 102/227 (44%), Gaps = 25/227 (11%)
Query: 167 ESKNEQEREKKENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKE 226
+S E+E E+K+ C GL NLGNTCF N+V+Q+LS T LR+ +
Sbjct: 479 DSVEEEEEEEKK-----------VCLPGFTGLVNLGNTCFMNSVIQSLSNTRELRDFFHD 527
Query: 227 VKMSGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVC 286
I P L G L + + L + + P +L + V
Sbjct: 528 RSFEAEINYNNP------------LGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVA 575
Query: 287 KKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYE 346
KA +F GY Q D+QE + +LLDG+ E+ R+ +S + DE + +
Sbjct: 576 SKASQFTGYAQHDAQEFMAFLLDGLH-EDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRH 634
Query: 347 KKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQ 393
K ++ SF+ +F G+ S ++C C VS+ + FL L +P+ Q
Sbjct: 635 KMRN-DSFIVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQ 680
Score = 70.9 bits (172), Expect = 5e-12
Identities = 64/214 (29%), Positives = 86/214 (40%), Gaps = 47/214 (21%)
Query: 611 EDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIK 670
EDP +A E ++ CL FTR E L C C + +
Sbjct: 1044 EDPGSA------GEAARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHR--------- 1088
Query: 671 GERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLR-KVNKHIKFP-EILDLAPFCTL 728
A KQ+L+ P VL + LKRF F R K+N ++FP LDL+ FC
Sbjct: 1089 --------EASKQLLLWRLPNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDLSKFCIG 1140
Query: 729 KCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQD-FEM 787
+ +E Y LY V+ H G M GHYTA A+ +P D
Sbjct: 1141 Q-----KEEQLPSYDLYAVINHYGGMIGGHYTACAR----------------LPNDRSSQ 1179
Query: 788 ESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYER 821
S W D+ V V ++V+ AY+LFY R
Sbjct: 1180 RSDVGWRLFDDSTVTTVDESQVVTRYAYVLFYRR 1213
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 86.7 bits (213), Expect = 8e-17
Identities = 58/211 (27%), Positives = 86/211 (40%), Gaps = 49/211 (23%)
Query: 620 LANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTN 679
+ N E + ++ CL +FTR E L + K+ C C H Y
Sbjct: 349 VVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGC-----------------HSYQE 391
Query: 680 AKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKN------- 732
+ KQ+ + P V HLKRF+ + RK+ ++ FP LD+ PF ++
Sbjct: 392 STKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQ 451
Query: 733 --VAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESK 790
N YSL+ VV H GT+ SGHYT++ + + K
Sbjct: 452 QPTDSLNNDNKYSLFAVVNHQGTLESGHYTSFIR-----------------------QHK 488
Query: 791 GQWFHISDTHVQAVPTTKVLNSQAYLLFYER 821
QWF D + VL+S+ YLLFY +
Sbjct: 489 DQWFKCDDAIITKASIKDVLDSEGYLLFYHK 519
Score = 80.9 bits (198), Expect = 5e-15
Identities = 81/322 (25%), Positives = 125/322 (38%), Gaps = 76/322 (23%)
Query: 74 CLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQ 133
CL C GC ++H +H +++ H L + L ++C++C
Sbjct: 76 CLYCVFFGC---FTKKHIHEH---AKAKRHNLAIDLMYGGIYCFLCQ------------- 116
Query: 134 VVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENPP---MNSP 190
DY+ + K ++ ++ +K ++E E + K NP + S
Sbjct: 117 --DYIYDKDMEIIAKEEQRKAWKMQGVGEKFSTWEPTKRELE----LLKHNPKRRKITSN 170
Query: 191 CQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEIN 250
C I ++GL NLGNTCF N ++Q L+ TP+LR D L++
Sbjct: 171 CTIGLRGLINLGNTCFMNCIVQALTHTPLLR------------------DFFLSDRHRCE 212
Query: 251 LEPPGP-LTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLD 309
++ P L MS E + P +L V A GY+QQD+ E L LD
Sbjct: 213 MQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALD 272
Query: 310 GMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPS----FVDRIFGGELTS 365
+ R KG D KK + P+ +D+IF G L S
Sbjct: 273 VL-----HRHCKG--------------------DDNGKKANNPNHCNCIIDQIFTGGLQS 307
Query: 366 MIMCDQCRTVSLVHESFLDLSL 387
+ C C VS + F D+SL
Sbjct: 308 DVTCQVCHGVSTTIDPFWDISL 329
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 86.3 bits (212), Expect = 1e-16
Identities = 64/200 (32%), Positives = 100/200 (50%), Gaps = 14/200 (7%)
Query: 190 PCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEI 249
P + GLSNLGNTCF N+ +Q +S T L + +SG + +L T P+ +
Sbjct: 526 PTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYF----ISGRHLY----ELNRTNPIGM 577
Query: 250 NLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLD 309
G + + E+ + V P +L + K A +F G+QQQDSQELL +LLD
Sbjct: 578 K----GHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLD 633
Query: 310 GMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMC 369
G+ E+ RV + +S + D E+ + D +++ VD +F G+L S + C
Sbjct: 634 GLH-EDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIIVD-LFHGQLRSQVKC 691
Query: 370 DQCRTVSLVHESFLDLSLPV 389
C +S+ + F LSLP+
Sbjct: 692 KTCGHISVRFDPFNFLSLPL 711
Score = 37.7 bits (86), Expect = 0.044
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 25/88 (28%)
Query: 736 ENTRV--LYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQW 793
E+T + +Y+LY + HSG + GHY YAK +W
Sbjct: 1304 EDTHIKPIYNLYAISCHSGILSGGHYITYAK-----------------------NPNCKW 1340
Query: 794 FHISDTHVQAVPTTKVLNSQAYLLFYER 821
+ +D+ + + ++ AY+LFYE+
Sbjct: 1341 YCYNDSSCEELHPDEIDTDSAYILFYEQ 1368
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/85 (25%), Positives = 34/85 (40%), Gaps = 17/85 (20%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
++ CL FT E+L ++ C C + A K++ + PP
Sbjct: 1032 NLDSCLRAFTSEEELGESEMYYCSKCK-----------------THCLATKKLDLWRLPP 1074
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKF 716
L +HLKRFQ K K ++F
Sbjct: 1075 FLIIHLKRFQFVNDQWIKSQKIVRF 1099
>gi|22550104 ubiquitin specific protease 32 [Homo sapiens]
Length = 1604
Score = 86.3 bits (212), Expect = 1e-16
Identities = 65/200 (32%), Positives = 100/200 (50%), Gaps = 14/200 (7%)
Query: 190 PCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEI 249
P + GLSNLGNTCF N+ +Q +S T L + +SG + +L T P+ +
Sbjct: 728 PTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYF----ISGRHLY----ELNRTNPIGM 779
Query: 250 NLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLD 309
G + + E+ + V P +L + K A RF G+QQQDSQELL +LLD
Sbjct: 780 K----GHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELLAFLLD 835
Query: 310 GMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMC 369
G+ E+ RV + +S + D E+ + D +++ VD +F G+L S + C
Sbjct: 836 GLH-EDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIVVD-LFHGQLRSQVKC 893
Query: 370 DQCRTVSLVHESFLDLSLPV 389
C +S+ + F LSLP+
Sbjct: 894 KTCGHISVRFDPFNFLSLPL 913
Score = 39.3 bits (90), Expect = 0.015
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 25/88 (28%)
Query: 736 ENTRV--LYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQW 793
E+TR+ +Y+LY + HSG + GHY YAK +W
Sbjct: 1502 EDTRIKPIYNLYAISCHSGILGGGHYVTYAK-----------------------NPNCKW 1538
Query: 794 FHISDTHVQAVPTTKVLNSQAYLLFYER 821
+ +D+ + + ++ AY+LFYE+
Sbjct: 1539 YCYNDSSCKELHPDEIDTDSAYILFYEQ 1566
Score = 38.9 bits (89), Expect = 0.020
Identities = 32/115 (27%), Positives = 42/115 (36%), Gaps = 22/115 (19%)
Query: 603 TKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQC 662
T VV+E A E N D C L FT E+L + C C
Sbjct: 1210 TSQERVVDEHESVEQSRRAQAEPINLDSC-----LRAFTSEEELGENEMYYCSKCK---- 1260
Query: 663 NGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP 717
+ A K++ + PP+L +HLKRFQ K K +KFP
Sbjct: 1261 -------------THCLATKKLDLWRLPPILIIHLKRFQFVNGRWIKSQKIVKFP 1302
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 85.5 bits (210), Expect = 2e-16
Identities = 57/194 (29%), Positives = 87/194 (44%), Gaps = 46/194 (23%)
Query: 627 NTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLI 686
+T +C++Q CL F++ EKL D N+ C C R+ ++ K++ I
Sbjct: 958 STSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR-----------------DSLKKIEI 1000
Query: 687 SLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLY 745
PPVL +HLKRF G +K+ + FP E LDL+ + + +N Y+L+
Sbjct: 1001 WKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYV------IGPKNNLKKYNLF 1054
Query: 746 GVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVP 805
V H G + GHYTAY K ++ +WF D V +
Sbjct: 1055 SVSNHYGGLDGGHYTAYCK----------------------NAARQRWFKFDDHEVSDIS 1092
Query: 806 TTKVLNSQAYLLFY 819
+ V +S AY+LFY
Sbjct: 1093 VSSVKSSAAYILFY 1106
Score = 69.7 bits (169), Expect = 1e-11
Identities = 53/194 (27%), Positives = 88/194 (45%), Gaps = 16/194 (8%)
Query: 197 GLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGP 256
GL NLGNTC+ N+++Q L P L + I + L G
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNL------------LGHKGE 825
Query: 257 LTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEH 316
+ + + + ++PK+ + K +F GY QQDSQELL +L+DG+ + +
Sbjct: 826 VAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLN 885
Query: 317 QRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSM-PSFVDRIFGGELTSMIMCDQCRTV 375
+ ++ K N + LD + K ++K K + S + +F G+ S + C C
Sbjct: 886 KADNRKRYKEENN--DHLD-DFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKK 942
Query: 376 SLVHESFLDLSLPV 389
S E+F+ LSLP+
Sbjct: 943 SRTFEAFMYLSLPL 956
Score = 33.9 bits (76), Expect = 0.63
Identities = 15/87 (17%), Positives = 43/87 (49%)
Query: 396 KKSVNDKNLKKTVEDEDQDSEEEKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQR 455
+K+ +K L++ ++E ++ +++ + K++ + Q+KAK++ +K+ Q
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQA 533
Query: 456 RQQKIQGKVLHLNDICTIDHPEDSEYE 482
+++ + +I + SE+E
Sbjct: 534 KKEDKETSAKRGKEITGVKRQSKSEHE 560
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 85.5 bits (210), Expect = 2e-16
Identities = 57/194 (29%), Positives = 87/194 (44%), Gaps = 46/194 (23%)
Query: 627 NTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLI 686
+T +C++Q CL F++ EKL D N+ C C R+ ++ K++ I
Sbjct: 958 STSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR-----------------DSLKKIEI 1000
Query: 687 SLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLY 745
PPVL +HLKRF G +K+ + FP E LDL+ + + +N Y+L+
Sbjct: 1001 WKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYV------IGPKNNLKKYNLF 1054
Query: 746 GVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVP 805
V H G + GHYTAY K ++ +WF D V +
Sbjct: 1055 SVSNHYGGLDGGHYTAYCK----------------------NAARQRWFKFDDHEVSDIS 1092
Query: 806 TTKVLNSQAYLLFY 819
+ V +S AY+LFY
Sbjct: 1093 VSSVKSSAAYILFY 1106
Score = 69.7 bits (169), Expect = 1e-11
Identities = 53/194 (27%), Positives = 88/194 (45%), Gaps = 16/194 (8%)
Query: 197 GLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGP 256
GL NLGNTC+ N+++Q L P L + I + L G
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNL------------LGHKGE 825
Query: 257 LTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEH 316
+ + + + ++PK+ + K +F GY QQDSQELL +L+DG+ + +
Sbjct: 826 VAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLN 885
Query: 317 QRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSM-PSFVDRIFGGELTSMIMCDQCRTV 375
+ ++ K N + LD + K ++K K + S + +F G+ S + C C
Sbjct: 886 KADNRKRYKEENN--DHLD-DFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKK 942
Query: 376 SLVHESFLDLSLPV 389
S E+F+ LSLP+
Sbjct: 943 SRTFEAFMYLSLPL 956
Score = 33.9 bits (76), Expect = 0.63
Identities = 15/87 (17%), Positives = 43/87 (49%)
Query: 396 KKSVNDKNLKKTVEDEDQDSEEEKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQR 455
+K+ +K L++ ++E ++ +++ + K++ + Q+KAK++ +K+ Q
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQA 533
Query: 456 RQQKIQGKVLHLNDICTIDHPEDSEYE 482
+++ + +I + SE+E
Sbjct: 534 KKEDKETSAKRGKEITGVKRQSKSEHE 560
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 85.5 bits (210), Expect = 2e-16
Identities = 57/194 (29%), Positives = 87/194 (44%), Gaps = 46/194 (23%)
Query: 627 NTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLI 686
+T +C++Q CL F++ EKL D N+ C C R+ ++ K++ I
Sbjct: 958 STSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR-----------------DSLKKIEI 1000
Query: 687 SLAPPVLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLY 745
PPVL +HLKRF G +K+ + FP E LDL+ + + +N Y+L+
Sbjct: 1001 WKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYV------IGPKNNLKKYNLF 1054
Query: 746 GVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVP 805
V H G + GHYTAY K ++ +WF D V +
Sbjct: 1055 SVSNHYGGLDGGHYTAYCK----------------------NAARQRWFKFDDHEVSDIS 1092
Query: 806 TTKVLNSQAYLLFY 819
+ V +S AY+LFY
Sbjct: 1093 VSSVKSSAAYILFY 1106
Score = 69.7 bits (169), Expect = 1e-11
Identities = 53/194 (27%), Positives = 88/194 (45%), Gaps = 16/194 (8%)
Query: 197 GLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGP 256
GL NLGNTC+ N+++Q L P L + I + L G
Sbjct: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNL------------LGHKGE 825
Query: 257 LTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEH 316
+ + + + ++PK+ + K +F GY QQDSQELL +L+DG+ + +
Sbjct: 826 VAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLN 885
Query: 317 QRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSM-PSFVDRIFGGELTSMIMCDQCRTV 375
+ ++ K N + LD + K ++K K + S + +F G+ S + C C
Sbjct: 886 KADNRKRYKEENN--DHLD-DFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKK 942
Query: 376 SLVHESFLDLSLPV 389
S E+F+ LSLP+
Sbjct: 943 SRTFEAFMYLSLPL 956
Score = 33.9 bits (76), Expect = 0.63
Identities = 15/87 (17%), Positives = 43/87 (49%)
Query: 396 KKSVNDKNLKKTVEDEDQDSEEEKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQR 455
+K+ +K L++ ++E ++ +++ + K++ + Q+KAK++ +K+ Q
Sbjct: 474 EKNKQEKELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQA 533
Query: 456 RQQKIQGKVLHLNDICTIDHPEDSEYE 482
+++ + +I + SE+E
Sbjct: 534 KKEDKETSAKRGKEITGVKRQSKSEHE 560
>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
Length = 963
Score = 85.1 bits (209), Expect = 2e-16
Identities = 67/233 (28%), Positives = 107/233 (45%), Gaps = 16/233 (6%)
Query: 157 IELENKKLEKESKNEQEREKKENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQ 216
I +E +K + + Q NM++E+ Q + GL+NLGNTCF N+ +Q LS
Sbjct: 272 IIMETRKKDGTWPSAQLHVMNNNMSEEDEDFKG--QPGICGLTNLGNTCFMNSALQCLSN 329
Query: 217 TPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVV 276
P L E + +L PL + G + A + + + +
Sbjct: 330 VPQLTEYF--------LNNCYLEELNFRNPLGMK----GEIAEAYADLVKQAWSGHHRSI 377
Query: 277 TPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDE 336
P ++V A +F GYQQ DSQELL +LLDG+ E+ RV K ++ + D+
Sbjct: 378 VPHVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLH-EDLNRVKKKEYVELCDAAGRPDQ 436
Query: 337 ELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 389
E+ + K+++ VD F G S ++C C VS+ + F LS+P+
Sbjct: 437 EVAQEAWQNHKRRNDSVIVD-TFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPL 488
Score = 70.1 bits (170), Expect = 8e-12
Identities = 53/190 (27%), Positives = 77/190 (40%), Gaps = 42/190 (22%)
Query: 633 IQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPV 692
+Q C+ FT E L N C C + Q A K++ + + P +
Sbjct: 781 LQECIELFTTVETLEKENPWYCPSCKQHQL-----------------ATKKLDLWMLPEI 823
Query: 693 LTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVL-YSLYGVVEHS 751
L +HLKRF F+ K++ ++FP I DL F + E N + Y L V H
Sbjct: 824 LIIHLKRFSYTKFSREKLDTLVEFP-IRDL-DFSEFVIQPQNESNPELYKYDLIAVSNHY 881
Query: 752 GTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVLN 811
G MR GHYT +A + GQW + D V V ++ +
Sbjct: 882 GGMRDGHYTTFACNK----------------------DSGQWHYFDDNSVSPVNENQIES 919
Query: 812 SQAYLLFYER 821
AY+LFY+R
Sbjct: 920 KAAYVLFYQR 929
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 83.6 bits (205), Expect = 7e-16
Identities = 55/199 (27%), Positives = 80/199 (40%), Gaps = 49/199 (24%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
++ CL +FTR E L + K+ C C Y + KQ+ ++ P
Sbjct: 262 TLTDCLRRFTRPEHLGSSAKIKCGSCQS-----------------YQESTKQLTMNKLPV 304
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKN---------VAEENTRVLY 742
V H KRF+ + RK+ +I FP LD+ PF ++ N Y
Sbjct: 305 VACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKY 364
Query: 743 SLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQ 802
SL+ VV H GT+ SGHYT++ + K QWF D +
Sbjct: 365 SLFAVVNHQGTLESGHYTSFIR-----------------------HHKDQWFKCDDAVIT 401
Query: 803 AVPTTKVLNSQAYLLFYER 821
VL+S+ YLLFY +
Sbjct: 402 KASIKDVLDSEGYLLFYHK 420
Score = 61.6 bits (148), Expect = 3e-09
Identities = 71/283 (25%), Positives = 110/283 (38%), Gaps = 68/283 (24%)
Query: 117 YVCDNEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQ---- 172
YV D +++ + + G+ + + QAS +T E+ +++ E+
Sbjct: 5 YVYDKDIEQIAKEEQGEAL---KLQASTST-----------EVSHQQCSVPGLGEKFPTW 50
Query: 173 EREKKE-NMAKENPP---MNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVK 228
E K E + NP + S I ++GL NLGNTCF N ++Q L+ TP+LR+ +
Sbjct: 51 ETTKPELELLGHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDR 110
Query: 229 MSGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKK 288
++ P+L L MS E+ P +L V
Sbjct: 111 HR---CEMPSPELC--------------LVCEMSSLFRELYSGNPSPHVPYKLLHLVWIH 153
Query: 289 AVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKK 348
A GY+QQD+ E L LD + R KG D K
Sbjct: 154 ARHLAGYRQQDAHEFLIAALDVL-----HRHCKG--------------------DDVGKA 188
Query: 349 KSMPS----FVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSL 387
+ P+ +D+IF G L S + C C VS + D+SL
Sbjct: 189 ANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISL 231
>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 82.4 bits (202), Expect = 2e-15
Identities = 63/192 (32%), Positives = 91/192 (47%), Gaps = 34/192 (17%)
Query: 631 CSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAP 690
C + L +FT E L + +C+ QCN + + V T A+KQ++I P
Sbjct: 515 CLVTEMLAKFTETEAL-EGKIYVCD-----QCNSKRRRFSS-KPVVLTEAQKQLMICHLP 567
Query: 691 PVLTLHLKRFQQAGFNLR-KVNKHIKFPEILDLAPFCTLK-CKNVAEENTRVLYSLYGVV 748
VL LHLKRF+ +G N R K+ H+ F EIL++ P+C + K++ E +Y L VV
Sbjct: 568 QVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPE--CFIYDLSAVV 625
Query: 749 EHSGT-MRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTT 807
H G SGHYTAY + E G W H +D+ +
Sbjct: 626 MHHGKGFGSGHYTAYC---------------------YNSEG-GFWVHCNDSKLSMCTMD 663
Query: 808 KVLNSQAYLLFY 819
+V +QAY+LFY
Sbjct: 664 EVCKAQAYILFY 675
Score = 64.7 bits (156), Expect = 3e-10
Identities = 72/301 (23%), Positives = 116/301 (38%), Gaps = 74/301 (24%)
Query: 134 VVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQI 193
+++ V Q TP KD K+ S+NE ++ ++ K P +
Sbjct: 224 IIEIVSVQVPAQTPASPAKD---------KVLSTSENEISQKVSDSSVKRRPIVTPG--- 271
Query: 194 TVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIV--------KIEPPDLALTE 245
V GL NLGNTC+ N+V+Q LS + R+ ++ ++ + + P + T
Sbjct: 272 -VTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTV 330
Query: 246 PLEIN---------------------------------LEPPGPLTLAMS------QFLN 266
++N ++P P + +S
Sbjct: 331 VYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQ 390
Query: 267 EMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKA 326
M K +V+P + V + F+GY QQD+QE L LLD ++ E L+
Sbjct: 391 VMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRE---------LET 441
Query: 327 FGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLS 386
G S L + K+ K + + V+ IF G+L S + C C S E F DLS
Sbjct: 442 TGTSLPALIPTSQRKL-----IKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLS 496
Query: 387 L 387
L
Sbjct: 497 L 497
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 20/100 (20%)
Query: 24 CRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCG 83
C+H+ + L+ +L +W+ C DC T S+W CL C H CG
Sbjct: 7 CKHVGQ-LQLAQDHSSLNPQKWH-CVDCNTTE--------------SIWACLSCSHVACG 50
Query: 84 RNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEV 123
R E+HALKH+ + H + L ++ V+CY+CD+ V
Sbjct: 51 RYI-EEHALKHF---QESSHPVALEVNEMYVFCYLCDDYV 86
>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 82.4 bits (202), Expect = 2e-15
Identities = 63/192 (32%), Positives = 91/192 (47%), Gaps = 34/192 (17%)
Query: 631 CSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAP 690
C + L +FT E L + +C+ QCN + + V T A+KQ++I P
Sbjct: 515 CLVTEMLAKFTETEAL-EGKIYVCD-----QCNSKRRRFSS-KPVVLTEAQKQLMICHLP 567
Query: 691 PVLTLHLKRFQQAGFNLR-KVNKHIKFPEILDLAPFCTLK-CKNVAEENTRVLYSLYGVV 748
VL LHLKRF+ +G N R K+ H+ F EIL++ P+C + K++ E +Y L VV
Sbjct: 568 QVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPE--CFIYDLSAVV 625
Query: 749 EHSGT-MRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTT 807
H G SGHYTAY + E G W H +D+ +
Sbjct: 626 MHHGKGFGSGHYTAYC---------------------YNSEG-GFWVHCNDSKLSMCTMD 663
Query: 808 KVLNSQAYLLFY 819
+V +QAY+LFY
Sbjct: 664 EVCKAQAYILFY 675
Score = 64.7 bits (156), Expect = 3e-10
Identities = 72/301 (23%), Positives = 116/301 (38%), Gaps = 74/301 (24%)
Query: 134 VVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQI 193
+++ V Q TP KD K+ S+NE ++ ++ K P +
Sbjct: 224 IIEIVSVQVPAQTPASPAKD---------KVLSTSENEISQKVSDSSVKRRPIVTPG--- 271
Query: 194 TVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIV--------KIEPPDLALTE 245
V GL NLGNTC+ N+V+Q LS + R+ ++ ++ + + P + T
Sbjct: 272 -VTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTV 330
Query: 246 PLEIN---------------------------------LEPPGPLTLAMS------QFLN 266
++N ++P P + +S
Sbjct: 331 VYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQ 390
Query: 267 EMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKA 326
M K +V+P + V + F+GY QQD+QE L LLD ++ E L+
Sbjct: 391 VMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRE---------LET 441
Query: 327 FGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLS 386
G S L + K+ K + + V+ IF G+L S + C C S E F DLS
Sbjct: 442 TGTSLPALIPTSQRKL-----IKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLS 496
Query: 387 L 387
L
Sbjct: 497 L 497
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 20/100 (20%)
Query: 24 CRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCG 83
C+H+ + L+ +L +W+ C DC T S+W CL C H CG
Sbjct: 7 CKHVGQ-LQLAQDHSSLNPQKWH-CVDCNTTE--------------SIWACLSCSHVACG 50
Query: 84 RNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEV 123
R E+HALKH+ + H + L ++ V+CY+CD+ V
Sbjct: 51 RYI-EEHALKHF---QESSHPVALEVNEMYVFCYLCDDYV 86
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 80.1 bits (196), Expect = 8e-15
Identities = 55/191 (28%), Positives = 81/191 (42%), Gaps = 45/191 (23%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
+++ CL F ++L+ N CE C + + N K + P
Sbjct: 538 TLEDCLAAFFAADELKGDNMYSCERCKKLR-----------------NGVKYCKVLRLPE 580
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLYGVVEH 750
+L +HLKRF+ K+N H+ FP E LDL PF +C + Y L V+ H
Sbjct: 581 ILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKECTSQI-----TTYDLLSVICH 635
Query: 751 SGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVL 810
GT SGHY AY + N++ GQW+ D +V V T V
Sbjct: 636 HGTAGSGHYIAYCQ---------NVI-------------NGQWYEFDDQYVTEVHETVVQ 673
Query: 811 NSQAYLLFYER 821
N++ Y+LFY +
Sbjct: 674 NAEGYVLFYRK 684
Score = 76.3 bits (186), Expect = 1e-13
Identities = 70/279 (25%), Positives = 123/279 (44%), Gaps = 49/279 (17%)
Query: 69 PSVWLCLK--CGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEV--- 123
P++W CL+ C + GCG + + H+ H +++ H L ++L + +WCY C+ EV
Sbjct: 38 PNLWACLQVACPYVGCGESFAD-HSTIH---AQAKKHNLTVNLTTFRLWCYACEKEVFLE 93
Query: 124 QYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKE 183
Q ++ LG ++ K +E+D+ K + +E E E +++ K
Sbjct: 94 QRLAAPLLG------------SSSKFSEQDSPPPSHPLKAVPIAVADEGESESEDDDLK- 140
Query: 184 NPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLAL 243
P +T G+ NLGN+C+ NA +Q LS P L + E G +V+ +
Sbjct: 141 ------PRGLT--GMKNLGNSCYMNAALQALSNCPPLTQFFLE---CGGLVRTDKKP--- 186
Query: 244 TEPLEINLEPPGPLTLAMSQFLNEMQETKK-GVVTPKELFSQVCKKAVRFKGYQQQDSQE 302
L + + ++E+ K+ V P L + F+GY QQD+QE
Sbjct: 187 ------------ALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQE 234
Query: 303 LLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNK 341
LR L+D + E + V + ++ D + K +
Sbjct: 235 FLRCLMDQLHEELKEPVVATVALTEARDSDSSDTDEKRE 273
Score = 37.0 bits (84), Expect = 0.075
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 347 KKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 389
K++ S + IF G + S++ C C VS E+F DLSLP+
Sbjct: 437 KEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 80.1 bits (196), Expect = 8e-15
Identities = 55/191 (28%), Positives = 81/191 (42%), Gaps = 45/191 (23%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
+++ CL F ++L+ N CE C + + N K + P
Sbjct: 538 TLEDCLAAFFAADELKGDNMYSCERCKKLR-----------------NGVKYCKVLRLPE 580
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLYGVVEH 750
+L +HLKRF+ K+N H+ FP E LDL PF +C + Y L V+ H
Sbjct: 581 ILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKECTSQI-----TTYDLLSVICH 635
Query: 751 SGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVL 810
GT SGHY AY + N++ GQW+ D +V V T V
Sbjct: 636 HGTAGSGHYIAYCQ---------NVI-------------NGQWYEFDDQYVTEVHETVVQ 673
Query: 811 NSQAYLLFYER 821
N++ Y+LFY +
Sbjct: 674 NAEGYVLFYRK 684
Score = 76.3 bits (186), Expect = 1e-13
Identities = 70/279 (25%), Positives = 123/279 (44%), Gaps = 49/279 (17%)
Query: 69 PSVWLCLK--CGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEV--- 123
P++W CL+ C + GCG + + H+ H +++ H L ++L + +WCY C+ EV
Sbjct: 38 PNLWACLQVACPYVGCGESFAD-HSTIH---AQAKKHNLTVNLTTFRLWCYACEKEVFLE 93
Query: 124 QYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKE 183
Q ++ LG ++ K +E+D+ K + +E E E +++ K
Sbjct: 94 QRLAAPLLG------------SSSKFSEQDSPPPSHPLKAVPIAVADEGESESEDDDLK- 140
Query: 184 NPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLAL 243
P +T G+ NLGN+C+ NA +Q LS P L + E G +V+ +
Sbjct: 141 ------PRGLT--GMKNLGNSCYMNAALQALSNCPPLTQFFLE---CGGLVRTDKKP--- 186
Query: 244 TEPLEINLEPPGPLTLAMSQFLNEMQETKK-GVVTPKELFSQVCKKAVRFKGYQQQDSQE 302
L + + ++E+ K+ V P L + F+GY QQD+QE
Sbjct: 187 ------------ALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQE 234
Query: 303 LLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNK 341
LR L+D + E + V + ++ D + K +
Sbjct: 235 FLRCLMDQLHEELKEPVVATVALTEARDSDSSDTDEKRE 273
Score = 37.0 bits (84), Expect = 0.075
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 347 KKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 389
K++ S + IF G + S++ C C VS E+F DLSLP+
Sbjct: 437 KEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 80.1 bits (196), Expect = 8e-15
Identities = 55/191 (28%), Positives = 81/191 (42%), Gaps = 45/191 (23%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
+++ CL F ++L+ N CE C + + N K + P
Sbjct: 538 TLEDCLAAFFAADELKGDNMYSCERCKKLR-----------------NGVKYCKVLRLPE 580
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFP-EILDLAPFCTLKCKNVAEENTRVLYSLYGVVEH 750
+L +HLKRF+ K+N H+ FP E LDL PF +C + Y L V+ H
Sbjct: 581 ILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKECTSQI-----TTYDLLSVICH 635
Query: 751 SGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVL 810
GT SGHY AY + N++ GQW+ D +V V T V
Sbjct: 636 HGTAGSGHYIAYCQ---------NVI-------------NGQWYEFDDQYVTEVHETVVQ 673
Query: 811 NSQAYLLFYER 821
N++ Y+LFY +
Sbjct: 674 NAEGYVLFYRK 684
Score = 76.3 bits (186), Expect = 1e-13
Identities = 70/279 (25%), Positives = 123/279 (44%), Gaps = 49/279 (17%)
Query: 69 PSVWLCLK--CGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEV--- 123
P++W CL+ C + GCG + + H+ H +++ H L ++L + +WCY C+ EV
Sbjct: 38 PNLWACLQVACPYVGCGESFAD-HSTIH---AQAKKHNLTVNLTTFRLWCYACEKEVFLE 93
Query: 124 QYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKE 183
Q ++ LG ++ K +E+D+ K + +E E E +++ K
Sbjct: 94 QRLAAPLLG------------SSSKFSEQDSPPPSHPLKAVPIAVADEGESESEDDDLK- 140
Query: 184 NPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLAL 243
P +T G+ NLGN+C+ NA +Q LS P L + E G +V+ +
Sbjct: 141 ------PRGLT--GMKNLGNSCYMNAALQALSNCPPLTQFFLE---CGGLVRTDKKP--- 186
Query: 244 TEPLEINLEPPGPLTLAMSQFLNEMQETKK-GVVTPKELFSQVCKKAVRFKGYQQQDSQE 302
L + + ++E+ K+ V P L + F+GY QQD+QE
Sbjct: 187 ------------ALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQE 234
Query: 303 LLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNK 341
LR L+D + E + V + ++ D + K +
Sbjct: 235 FLRCLMDQLHEELKEPVVATVALTEARDSDSSDTDEKRE 273
Score = 37.0 bits (84), Expect = 0.075
Identities = 17/43 (39%), Positives = 25/43 (58%)
Query: 347 KKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPV 389
K++ S + IF G + S++ C C VS E+F DLSLP+
Sbjct: 437 KEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
>gi|239742287 PREDICTED: hypothetical protein XP_002342475 [Homo
sapiens]
Length = 530
Score = 80.1 bits (196), Expect = 8e-15
Identities = 58/190 (30%), Positives = 87/190 (45%), Gaps = 51/190 (26%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
S+Q L Q + E+L N C VC +R A K + + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQR-----------------APASKTLTLHTSAK 274
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVL-YSLYGVVEH 750
VL L LKRF N K+ K++++PE LD+ P+ ++++NT L Y LY V+ H
Sbjct: 275 VLILVLKRFSDVTGN--KIAKNVQYPECLDMQPY-------MSQQNTGPLVYVLYAVLVH 325
Query: 751 SG-TMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKV 809
+G + +GHY +Y KA+ +GQW+ + D V A T V
Sbjct: 326 AGWSCHNGHYFSYVKAQ-----------------------EGQWYKMDDAEVTAASITSV 362
Query: 810 LNSQAYLLFY 819
L+ QAY+LFY
Sbjct: 363 LSQQAYVLFY 372
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/236 (22%), Positives = 96/236 (40%), Gaps = 52/236 (22%)
Query: 182 KENPPMNSPCQITV-KGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 240
+E P++S V GL N+GNTC+ NA +Q L+ TP L + + S T + +
Sbjct: 65 REKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHK--- 121
Query: 241 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 300
G + M + V+ P + A F +Q+D+
Sbjct: 122 --------------GCMLCTMQAHITRALHNPGHVIQPSQAL------AAGFHRGKQEDA 161
Query: 301 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFG 360
E L + +D M+ KA +++D K+ + + +IFG
Sbjct: 162 HEFLMFTVDAMK------------KACLPGHKQVDHHSKD-----------TTLIHQIFG 198
Query: 361 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSE 416
G S I C C +S + +LD++L + QS +++ L++ V+ E+ + E
Sbjct: 199 GYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQA-----LEQLVKPEELNGE 249
>gi|239742282 PREDICTED: hypothetical protein XP_002342474 [Homo
sapiens]
Length = 530
Score = 80.1 bits (196), Expect = 8e-15
Identities = 58/190 (30%), Positives = 87/190 (45%), Gaps = 51/190 (26%)
Query: 632 SIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPP 691
S+Q L Q + E+L N C VC +R A K + + +
Sbjct: 232 SVQQALEQLVKPEELNGENAYHCGVCLQR-----------------APASKTLTLHTSAK 274
Query: 692 VLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVL-YSLYGVVEH 750
VL L LKRF N K+ K++++PE LD+ P+ ++++NT L Y LY V+ H
Sbjct: 275 VLILVLKRFSDVTGN--KIAKNVQYPECLDMQPY-------MSQQNTGPLVYVLYAVLVH 325
Query: 751 SG-TMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKV 809
+G + +GHY +Y KA+ +GQW+ + D V A T V
Sbjct: 326 AGWSCHNGHYFSYVKAQ-----------------------EGQWYKMDDAEVTAASITSV 362
Query: 810 LNSQAYLLFY 819
L+ QAY+LFY
Sbjct: 363 LSQQAYVLFY 372
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/243 (22%), Positives = 99/243 (40%), Gaps = 52/243 (21%)
Query: 175 EKKENMAKENPPMNSPCQITV-KGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTI 233
E ++ +E P++S V GL N+GNTC+ NA +Q L+ TP L + + S T
Sbjct: 58 EARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTC 117
Query: 234 VKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFK 293
+ + G + M + V+ P + A F
Sbjct: 118 HRHK-----------------GCMLCTMQAHITRALHNPGHVIQPSQAL------AAGFH 154
Query: 294 GYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPS 353
+Q+D+ E L + +D M+ KA +++D K+ +
Sbjct: 155 RGKQEDAHEFLMFTVDAMK------------KACLPGHKQVDHPSKD-----------TT 191
Query: 354 FVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQ 413
+ +IFGG S I C C +S + +LD++L + QS +++ L++ V+ E+
Sbjct: 192 LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQA-----LEQLVKPEEL 246
Query: 414 DSE 416
+ E
Sbjct: 247 NGE 249
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,867,188
Number of Sequences: 37866
Number of extensions: 1580152
Number of successful extensions: 10710
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 260
Number of HSP's that attempted gapping in prelim test: 8485
Number of HSP's gapped (non-prelim): 1928
length of query: 823
length of database: 18,247,518
effective HSP length: 111
effective length of query: 712
effective length of database: 14,044,392
effective search space: 9999607104
effective search space used: 9999607104
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.