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Search of human proteins with 5453994
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453994 RAD21 homolog [Homo sapiens]
(631 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453994 RAD21 homolog [Homo sapiens] 1269 0.0
gi|222136644 RAD21-like 1 [Homo sapiens] 421 e-117
gi|115430231 REC8 homolog [Homo sapiens] 72 2e-12
gi|115430229 REC8 homolog [Homo sapiens] 72 2e-12
gi|122937247 unc-13 homolog A [Homo sapiens] 55 1e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 52 1e-06
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2... 47 5e-05
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1... 47 5e-05
gi|221139761 zinc finger protein 853 [Homo sapiens] 46 9e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 46 9e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 46 9e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 9e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 9e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 9e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 46 9e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 45 2e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 45 3e-04
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi... 44 3e-04
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi... 44 3e-04
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens] 44 3e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 44 5e-04
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 44 6e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 43 8e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 43 8e-04
gi|7657455 pescadillo homolog 1, containing BRCT domain [Homo sa... 42 0.001
gi|110349719 titin isoform N2-A [Homo sapiens] 42 0.002
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 42 0.002
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 42 0.002
gi|148746195 trichohyalin [Homo sapiens] 42 0.002
gi|4502805 chromogranin A precursor [Homo sapiens] 41 0.003
>gi|5453994 RAD21 homolog [Homo sapiens]
Length = 631
Score = 1269 bits (3284), Expect = 0.0
Identities = 631/631 (100%), Positives = 631/631 (100%)
Query: 1 MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLL 60
MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLL
Sbjct: 1 MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLL 60
Query: 61 LGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQP 120
LGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQP
Sbjct: 61 LGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQP 120
Query: 121 LPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDD 180
LPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDD
Sbjct: 121 LPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDD 180
Query: 181 DMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGG 240
DMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGG
Sbjct: 181 DMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGG 240
Query: 241 IFDDPPALSEAGVMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNE 300
IFDDPPALSEAGVMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNE
Sbjct: 241 IFDDPPALSEAGVMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNE 300
Query: 301 EEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKL 360
EEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKL
Sbjct: 301 EEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKL 360
Query: 361 MMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEF 420
MMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEF
Sbjct: 361 MMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEF 420
Query: 421 ENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKA 480
ENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKA
Sbjct: 421 ENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKA 480
Query: 481 GQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEE 540
GQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEE
Sbjct: 481 GQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEE 540
Query: 541 DEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSF 600
DEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSF
Sbjct: 541 DEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSF 600
Query: 601 LVLKKQQAIELTQEEPYSDIIATPGPRFHII 631
LVLKKQQAIELTQEEPYSDIIATPGPRFHII
Sbjct: 601 LVLKKQQAIELTQEEPYSDIIATPGPRFHII 631
>gi|222136644 RAD21-like 1 [Homo sapiens]
Length = 556
Score = 421 bits (1081), Expect = e-117
Identities = 271/633 (42%), Positives = 374/633 (59%), Gaps = 79/633 (12%)
Query: 1 MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLL 60
MFY H ++SKRGPLAKIWLAAHW+KKLTKAHVFECNLE ++E I+SPKVK+ALRTSGHLL
Sbjct: 1 MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIEKILSPKVKIALRTSGHLL 60
Query: 61 LGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAYNAITLPEEFHDFDQP 120
LGVVRIY+RKAKYLLADC+EAF+K+KM F PG+VDLP+EN EA+YNAITLPEEFHDFD
Sbjct: 61 LGVVRIYNRKAKYLLADCSEAFLKMKMTFCPGLVDLPKENFEASYNAITLPEEFHDFD-- 118
Query: 121 LPDLDDIDVAQQFSLNQSRVEEITMREEVGNISILQENDFGDFGMDDREIMREGSAFEDD 180
+++ IDV++ F+ NQSR EEIT+RE N I Q FG ++ EI+R S F+D+
Sbjct: 119 TQNMNAIDVSEHFTQNQSRPEEITLRENFDNDLIFQAESFG----EESEILRRHSFFDDN 174
Query: 181 DMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGEGNDGGILDDKLISNNDGG 240
+L +S L+ E S+ +L + L Y+ D FG+ G + D L+ ++
Sbjct: 175 ILL---NSSGPLI--EHSSGSLTGE-RSLFYD---SGDGFGDEGAAGEMIDNLLQDDQNI 225
Query: 241 IFDDPPALSEAGVMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNE 300
+ +D E + LP +P + E DN S P ++T L+ E
Sbjct: 226 LLEDMHLNRE--ISLPSEPPNSLAVEPDN----------SECICVPENEKMNETILLSTE 273
Query: 301 EEAFALEPIDIT-VKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKK 359
EE F L+PIDI+ + E + +KR+L++D +KEL SK I QL+ ++D + L+LAPPT++
Sbjct: 274 EEGFTLDPIDISDIAEKRKGKKRRLLIDPIKELSSKVIHKQLTSFADTLMVLELAPPTQR 333
Query: 360 LMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKE 419
LMMWK+ GGV L S AQ L + L LFT+C + + RK
Sbjct: 334 LMMWKKRGGVHTLLSTAAQDLIHAELKMLFTKC---FLSSGFKLGRK------------- 377
Query: 420 FENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRK 479
+ +E +++ +++++ +++EP+ QE + +T D G +
Sbjct: 378 ----MIQKESVREEVGNQNIVETSMMQEPNYQQE--LSKPQTWKDVIG-------GSQHS 424
Query: 480 AGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLI-PELELLPEKEKEKEKEKEDDEE 538
+ + + + Q + +M V L EE + L E+E P E E +EE
Sbjct: 425 SHEDTNKNINSEQDIVEM----VSLAAEESSLMNDLFAQEIEYSP-----VELESLSNEE 475
Query: 539 EEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFY 598
+ E RWN R QML+ L R K G +S SL++LCRN++RKQAAAKFY
Sbjct: 476 -----------NIETERWNGRILQMLNRL-RESNKMGMQSFSLMKLCRNSDRKQAAAKFY 523
Query: 599 SFLVLKKQQAIELTQEEPYSDIIATPGPRFHII 631
SFLVLKKQ AIEL+Q PY+DIIAT GP F+ I
Sbjct: 524 SFLVLKKQLAIELSQSAPYADIIATMGPMFYNI 556
>gi|115430231 REC8 homolog [Homo sapiens]
Length = 547
Score = 71.6 bits (174), Expect = 2e-12
Identities = 146/672 (21%), Positives = 237/672 (35%), Gaps = 168/672 (25%)
Query: 1 MFYAHFVLSKR-GPLAKIWLAAHWDKKLTKAHVFECNLESSVESIIS------------- 46
MFY VL + G A IWLAA +L K N+ + E I++
Sbjct: 1 MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGL 60
Query: 47 PKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAY- 105
P+ + +L S L +GV+R+Y ++ +YL+ D ++ A +D+ E
Sbjct: 61 PRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLP 120
Query: 106 NAITLPEEFHDFDQPLPDLDDID--VAQQFSLNQSR-VEEITMREEVGNISILQENDFGD 162
N + + E D P + +D + F + Q R + E + E V I
Sbjct: 121 NHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEI---------- 170
Query: 163 FGMDDREIMREGSAFEDDDMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGE 222
E+ E E + V + +LE+ E I LE E + +
Sbjct: 171 ----PPEVPTEPREPERIPVTVLPPEAITILEA--------EPIRMLEIEGERELPEVSR 218
Query: 223 GNDGGILDDKLISNNDGGIFDD-----PPALSE----AGVMLPEQ---------PAHDDM 264
D LI+ + I + PPA +E + PE+ ++
Sbjct: 219 RE-----LDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEV 273
Query: 265 DEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKL 324
+ + + P SP+ PV P P + +R+R L
Sbjct: 274 TPPEELRLPAPPSPERRPPVPPPP---------------------------RRRRRRRLL 306
Query: 325 IVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLW-NN 383
D ++ + + QL + + PP + + G +LF P W
Sbjct: 307 FWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIR------GPAELFRTPTLSGWLPP 360
Query: 384 RLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEP 443
LL L+T C P P+ LR+ E+P E ++ +++
Sbjct: 361 ELLGLWTHCAQP-PPKALRR--------------------ELPEEAAAEEERRK------ 393
Query: 444 IIEEPSRLQ--ESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPP 501
IE PS ++ +E S + + + K + I PE +VE E P
Sbjct: 394 -IEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPA 452
Query: 502 VELPPEEP--PNICQLI--PELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWN 557
+ + PE P P L+ PELELL + + E E + +S
Sbjct: 453 LPVVPELPEVPMEMPLVLPPELELLSLEAVHRAVALELQANREPDFSS------------ 500
Query: 558 KRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPY 617
+S L + R+ AA FY LVL QQ + + QE+PY
Sbjct: 501 --------------------LVSPL-----SPRRMAARVFYLLLVLSAQQILHVKQEKPY 535
Query: 618 SDIIATPGPRFH 629
++ PGPRFH
Sbjct: 536 GRLLIQPGPRFH 547
>gi|115430229 REC8 homolog [Homo sapiens]
Length = 547
Score = 71.6 bits (174), Expect = 2e-12
Identities = 146/672 (21%), Positives = 237/672 (35%), Gaps = 168/672 (25%)
Query: 1 MFYAHFVLSKR-GPLAKIWLAAHWDKKLTKAHVFECNLESSVESIIS------------- 46
MFY VL + G A IWLAA +L K N+ + E I++
Sbjct: 1 MFYYPNVLQRHTGCFATIWLAATRGSRLVKREYLRVNVVKTCEEILNYVLVRVQPPQPGL 60
Query: 47 PKVKMALRTSGHLLLGVVRIYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEENREAAY- 105
P+ + +L S L +GV+R+Y ++ +YL+ D ++ A +D+ E
Sbjct: 61 PRPRFSLYLSAQLQIGVIRVYSQQCQYLVEDIQHILERLHRAQLQIRIDMETELPSLLLP 120
Query: 106 NAITLPEEFHDFDQPLPDLDDID--VAQQFSLNQSR-VEEITMREEVGNISILQENDFGD 162
N + + E D P + +D + F + Q R + E + E V I
Sbjct: 121 NHLAMMETLEDAPDPFFGMMSVDPRLPSPFDIPQIRHLLEAAIPERVEEI---------- 170
Query: 163 FGMDDREIMREGSAFEDDDMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQYKDDNFGE 222
E+ E E + V + +LE+ E I LE E + +
Sbjct: 171 ----PPEVPTEPREPERIPVTVLPPEAITILEA--------EPIRMLEIEGERELPEVSR 218
Query: 223 GNDGGILDDKLISNNDGGIFDD-----PPALSE----AGVMLPEQ---------PAHDDM 264
D LI+ + I + PPA +E + PE+ ++
Sbjct: 219 RE-----LDLLIAEEEEAILLEIPRLPPPAPAEVEGIGEALGPEELRLTGWEPGALLMEV 273
Query: 265 DEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPNEEEAFALEPIDITVKETKAKRKRKL 324
+ + + P SP+ PV P P + +R+R L
Sbjct: 274 TPPEELRLPAPPSPERRPPVPPPP---------------------------RRRRRRRLL 306
Query: 325 IVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPAQPLW-NN 383
D ++ + + QL + + PP + + G +LF P W
Sbjct: 307 FWDKETQISPEKFQEQLQTRAHCWECPMVQPPERTIR------GPAELFRTPTLSGWLPP 360
Query: 384 RLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEP 443
LL L+T C P P+ LR+ E+P E ++ +++
Sbjct: 361 ELLGLWTHCAQP-PPKALRR--------------------ELPEEAAAEEERRK------ 393
Query: 444 IIEEPSRLQ--ESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPP 501
IE PS ++ +E S + + + K + I PE +VE E P
Sbjct: 394 -IEVPSEIEVPREALEPSVPLMVSLEISLEAAEEEKSRISLIPPEERWAWPEVEAPEAPA 452
Query: 502 VELPPEEP--PNICQLI--PELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWN 557
+ + PE P P L+ PELELL + + E E + +S
Sbjct: 453 LPVVPELPEVPMEMPLVLPPELELLSLEAVHRAVALELQANREPDFSS------------ 500
Query: 558 KRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEPY 617
+S L + R+ AA FY LVL QQ + + QE+PY
Sbjct: 501 --------------------LVSPL-----SPRRMAARVFYLLLVLSAQQILHVKQEKPY 535
Query: 618 SDIIATPGPRFH 629
++ PGPRFH
Sbjct: 536 GRLLIQPGPRFH 547
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 55.5 bits (132), Expect = 1e-07
Identities = 39/156 (25%), Positives = 77/156 (49%), Gaps = 14/156 (8%)
Query: 409 EADNLDEFLKEF-ENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESA 467
+ + L+E L++F E E+P ++++ + ++ +V D+ +E V A + +
Sbjct: 408 DEEELEEDLEDFLEEEELPEDEEELEEEEEEVPDDL---GSYAQREDVAVAEPKDFKRIS 464
Query: 468 MPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEK 527
+PP P G+ D PV P + + ++ P P++ P + IPE E P K++
Sbjct: 465 LPPAAP-------GKEDKAPVAPTEAPDMAKVAPKPATPDKVP-AAEQIPEAE--PPKDE 514
Query: 528 EKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQM 563
E + +ED+E +E +D+ + R +NK Q+
Sbjct: 515 ESFRPREDEEGQEGQDSMSRAKANWLRAFNKVRMQL 550
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 52.4 bits (124), Expect = 1e-06
Identities = 32/102 (31%), Positives = 55/102 (53%), Gaps = 14/102 (13%)
Query: 466 SAMPPPP----PQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEE------PPNICQL 515
+A PP P P+ + G + P P PP + +PP +L PE PP + +
Sbjct: 818 TASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEED 877
Query: 516 IPELELLP----EKEKEKEKEKEDDEEEEDEDASGGDQDQEE 553
+ + + E+E+E+E+E+E++EEEE+ED ++D+EE
Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEE 919
Score = 40.8 bits (94), Expect = 0.004
Identities = 35/125 (28%), Positives = 57/125 (45%), Gaps = 9/125 (7%)
Query: 423 PEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQ 482
PE P + Q + + ++ E +EEP +E + + T E+ P QG + G+
Sbjct: 989 PESPPKVQPEPEPEPGLLLE--VEEPGTEEERGADTAPTLAPEAL----PSQGEVEREGE 1042
Query: 483 IDPEPVMPPQQV--EQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEE 540
P PPQ++ E+ PP L E ++ P E E+E E E E E +E+E
Sbjct: 1043 -SPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKE 1101
Query: 541 DEDAS 545
+D +
Sbjct: 1102 QDDTA 1106
>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
[Homo sapiens]
Length = 659
Score = 47.0 bits (110), Expect = 5e-05
Identities = 44/184 (23%), Positives = 74/184 (40%), Gaps = 23/184 (12%)
Query: 378 QPLWNNRLLKLFTRCLTP-LVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQ----- 431
+P W+ +L ++ L P DL + K D D N +V +D+Q
Sbjct: 374 KPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMAD---LPVPNQDVTSDDKQALKST 430
Query: 432 -QQHQQRDVIDEPIIEEPS---RLQESVMEASRTNIDESAM-------PPPPPQGVKRKA 480
+ +DV ++P + S + + S T+I+E+ PPP PQ +A
Sbjct: 431 INEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRA 490
Query: 481 GQIDPEPVMPPQ---QVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDE 537
+D V P + PP LPP P+ + + E ELLP+ + + E
Sbjct: 491 SSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSP 550
Query: 538 EEED 541
++D
Sbjct: 551 AKKD 554
>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
[Homo sapiens]
Length = 660
Score = 47.0 bits (110), Expect = 5e-05
Identities = 44/184 (23%), Positives = 74/184 (40%), Gaps = 23/184 (12%)
Query: 378 QPLWNNRLLKLFTRCLTP-LVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQ----- 431
+P W+ +L ++ L P DL + K D D N +V +D+Q
Sbjct: 375 KPKWDCQLFDSYSESLPANQQPRDLNRMEKTSVKDMAD---LPVPNQDVTSDDKQALKST 431
Query: 432 -QQHQQRDVIDEPIIEEPS---RLQESVMEASRTNIDESAM-------PPPPPQGVKRKA 480
+ +DV ++P + S + + S T+I+E+ PPP PQ +A
Sbjct: 432 INEALPKDVSEDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRA 491
Query: 481 GQIDPEPVMPPQ---QVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDE 537
+D V P + PP LPP P+ + + E ELLP+ + + E
Sbjct: 492 SSLDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQSEQVSEAELLPQLSRAPSQAAESSP 551
Query: 538 EEED 541
++D
Sbjct: 552 AKKD 555
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 46.2 bits (108), Expect = 9e-05
Identities = 38/177 (21%), Positives = 90/177 (50%), Gaps = 17/177 (9%)
Query: 399 EDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQ---HQQRDVIDEPIIEEPSRLQESV 455
E L++++ + + L + ++F+ + + QQQ QQ + + + ++ ++LQ+ +
Sbjct: 209 EQLQQQQLLQQQEQLQQ--QQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQL 266
Query: 456 MEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQL 515
+E + + + + Q +++ Q+ + +Q++Q ++ P L PEE +
Sbjct: 267 LEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQ---QEQLQQQQLQPPPLEPEEEEEV--- 320
Query: 516 IPELELLP-EKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRAL 571
ELEL+P + E+E E++ E E ++ ++ QE+R+ + Q+ L L++ L
Sbjct: 321 --ELELMPVDLGSEQELEQQRQELERQQEL---ERQQEQRQLQLKLQEELQQLEQQL 372
Score = 38.1 bits (87), Expect = 0.025
Identities = 36/200 (18%), Positives = 88/200 (44%), Gaps = 7/200 (3%)
Query: 421 ENPEVPREDQQQQHQQRDVIDEPI----IEEPSRLQESVMEASRTNIDESAMPPPPPQGV 476
E+ E ++ QR + P+ I E +R + ++ + +++ P PQ
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQ--LEQQPEPQQQPQHE 107
Query: 477 KRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEK-EKEKEKED 535
+ + Q E PQQ Q ++ ++ + + +L PEL+L+ ++++ + ++ +E
Sbjct: 108 QLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQ 167
Query: 536 DEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRNTNRKQAAA 595
++ ++ Q QE++ ++ Q ++ L + E + +L + + Q
Sbjct: 168 QRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQ 227
Query: 596 KFYSFLVLKKQQAIELTQEE 615
L++QQ + L Q++
Sbjct: 228 FQQQQEQLQQQQQLLLLQQQ 247
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/138 (18%), Positives = 67/138 (48%), Gaps = 4/138 (2%)
Query: 428 EDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEP 487
+ Q Q QQ + + + ++ ++LQ+ ++ + + + Q ++ Q P
Sbjct: 251 QQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPP 310
Query: 488 VMPPQQVE--QMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDAS 545
+ P++ E ++E+ PV+L E+ + Q ELE E E+++E+ + + +E+
Sbjct: 311 PLEPEEEEEVELELMPVDLGSEQ--ELEQQRQELERQQELERQQEQRQLQLKLQEELQQL 368
Query: 546 GGDQDQEERRWNKRTQQM 563
+Q++++ ++ Q+
Sbjct: 369 EQQLEQQQQQLEQQEVQL 386
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 46.2 bits (108), Expect = 9e-05
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 29/209 (13%)
Query: 400 DLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEAS 459
++ + E D L++ ++ E RE Q++Q +Q++ E EE + +E+ E S
Sbjct: 143 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE--RERRAEERRKEREARREVS 200
Query: 460 ---RTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELP-PEEPPNICQL 515
RT ++ + K KA P PP+ E+ E+ P EE L
Sbjct: 201 AHHRTMREDYSD--------KVKASHWSRSPPRPPR--ERFELGDGRKPVKEEKMEERDL 250
Query: 516 IPELELLPEKEKEKE-------------KEKEDDEEEEDEDASGGDQDQEERRWNKRTQQ 562
+ +L+ + + E++ +E+E++EEEE+E+ S ++ +EE + ++
Sbjct: 251 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 310
Query: 563 MLHGLQRALAKTGAESISLLELCRNTNRK 591
++ AE +S E+ + R+
Sbjct: 311 ETGSNSEEASEQSAEEVSEEEMSEDEERE 339
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 46.2 bits (108), Expect = 9e-05
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 29/209 (13%)
Query: 400 DLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEAS 459
++ + E D L++ ++ E RE Q++Q +Q++ E EE + +E+ E S
Sbjct: 153 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE--RERRAEERRKEREARREVS 210
Query: 460 ---RTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELP-PEEPPNICQL 515
RT ++ + K KA P PP+ E+ E+ P EE L
Sbjct: 211 AHHRTMREDYSD--------KVKASHWSRSPPRPPR--ERFELGDGRKPVKEEKMEERDL 260
Query: 516 IPELELLPEKEKEKE-------------KEKEDDEEEEDEDASGGDQDQEERRWNKRTQQ 562
+ +L+ + + E++ +E+E++EEEE+E+ S ++ +EE + ++
Sbjct: 261 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 320
Query: 563 MLHGLQRALAKTGAESISLLELCRNTNRK 591
++ AE +S E+ + R+
Sbjct: 321 ETGSNSEEASEQSAEEVSEEEMSEDEERE 349
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 46.2 bits (108), Expect = 9e-05
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 29/209 (13%)
Query: 400 DLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEAS 459
++ + E D L++ ++ E RE Q++Q +Q++ E EE + +E+ E S
Sbjct: 144 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE--RERRAEERRKEREARREVS 201
Query: 460 ---RTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELP-PEEPPNICQL 515
RT ++ + K KA P PP+ E+ E+ P EE L
Sbjct: 202 AHHRTMREDYSD--------KVKASHWSRSPPRPPR--ERFELGDGRKPVKEEKMEERDL 251
Query: 516 IPELELLPEKEKEKE-------------KEKEDDEEEEDEDASGGDQDQEERRWNKRTQQ 562
+ +L+ + + E++ +E+E++EEEE+E+ S ++ +EE + ++
Sbjct: 252 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 311
Query: 563 MLHGLQRALAKTGAESISLLELCRNTNRK 591
++ AE +S E+ + R+
Sbjct: 312 ETGSNSEEASEQSAEEVSEEEMSEDEERE 340
Score = 32.0 bits (71), Expect = 1.8
Identities = 42/187 (22%), Positives = 72/187 (38%), Gaps = 38/187 (20%)
Query: 413 LDEFLKEF-------ENPEVPR-EDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNID 464
LDE L+E E E+ R ++ + +RD ++E L++ ME + N
Sbjct: 13 LDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEE------GELRDHCMEITIRN-- 64
Query: 465 ESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPE 524
P ++ + + D + PPQQ+ + E V +E
Sbjct: 65 ---SPYRREDSMEDRGEEDDSLAIKPPQQMSRKE--KVHHRKDEK--------------R 105
Query: 525 KEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLEL 584
KEK+ + KE + E E +QD+ R W + Q + R ++ + + LE
Sbjct: 106 KEKKHARVKEKEREHERRKRHREEQDKARREWER---QKRREMAREHSRRERDRLEQLER 162
Query: 585 CRNTNRK 591
R RK
Sbjct: 163 KRERERK 169
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 46.2 bits (108), Expect = 9e-05
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 29/209 (13%)
Query: 400 DLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEAS 459
++ + E D L++ ++ E RE Q++Q +Q++ E EE + +E+ E S
Sbjct: 121 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE--RERRAEERRKEREARREVS 178
Query: 460 ---RTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELP-PEEPPNICQL 515
RT ++ + K KA P PP+ E+ E+ P EE L
Sbjct: 179 AHHRTMREDYSD--------KVKASHWSRSPPRPPR--ERFELGDGRKPVKEEKMEERDL 228
Query: 516 IPELELLPEKEKEKE-------------KEKEDDEEEEDEDASGGDQDQEERRWNKRTQQ 562
+ +L+ + + E++ +E+E++EEEE+E+ S ++ +EE + ++
Sbjct: 229 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 288
Query: 563 MLHGLQRALAKTGAESISLLELCRNTNRK 591
++ AE +S E+ + R+
Sbjct: 289 ETGSNSEEASEQSAEEVSEEEMSEDEERE 317
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 46.2 bits (108), Expect = 9e-05
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 29/209 (13%)
Query: 400 DLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEAS 459
++ + E D L++ ++ E RE Q++Q +Q++ E EE + +E+ E S
Sbjct: 110 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE--RERRAEERRKEREARREVS 167
Query: 460 ---RTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELP-PEEPPNICQL 515
RT ++ + K KA P PP+ E+ E+ P EE L
Sbjct: 168 AHHRTMREDYSD--------KVKASHWSRSPPRPPR--ERFELGDGRKPVKEEKMEERDL 217
Query: 516 IPELELLPEKEKEKE-------------KEKEDDEEEEDEDASGGDQDQEERRWNKRTQQ 562
+ +L+ + + E++ +E+E++EEEE+E+ S ++ +EE + ++
Sbjct: 218 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 277
Query: 563 MLHGLQRALAKTGAESISLLELCRNTNRK 591
++ AE +S E+ + R+
Sbjct: 278 ETGSNSEEASEQSAEEVSEEEMSEDEERE 306
Score = 30.4 bits (67), Expect = 5.2
Identities = 31/141 (21%), Positives = 52/141 (36%), Gaps = 19/141 (13%)
Query: 451 LQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPP 510
L+E + R I P ++ + + D + PPQQ+ + E V +E
Sbjct: 14 LEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKE--KVHHRKDEK- 70
Query: 511 NICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRA 570
KEK+ + KE + E E +QD+ R W + Q + R
Sbjct: 71 -------------RKEKKHARVKEKEREHERRKRHREEQDKARREWER---QKRREMARE 114
Query: 571 LAKTGAESISLLELCRNTNRK 591
++ + + LE R RK
Sbjct: 115 HSRRERDRLEQLERKRERERK 135
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 46.2 bits (108), Expect = 9e-05
Identities = 46/209 (22%), Positives = 92/209 (44%), Gaps = 29/209 (13%)
Query: 400 DLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEAS 459
++ + E D L++ ++ E RE Q++Q +Q++ E EE + +E+ E S
Sbjct: 155 EMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE--RERRAEERRKEREARREVS 212
Query: 460 ---RTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELP-PEEPPNICQL 515
RT ++ + K KA P PP+ E+ E+ P EE L
Sbjct: 213 AHHRTMREDYSD--------KVKASHWSRSPPRPPR--ERFELGDGRKPVKEEKMEERDL 262
Query: 516 IPELELLPEKEKEKE-------------KEKEDDEEEEDEDASGGDQDQEERRWNKRTQQ 562
+ +L+ + + E++ +E+E++EEEE+E+ S ++ +EE + ++
Sbjct: 263 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE 322
Query: 563 MLHGLQRALAKTGAESISLLELCRNTNRK 591
++ AE +S E+ + R+
Sbjct: 323 ETGSNSEEASEQSAEEVSEEEMSEDEERE 351
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 45.1 bits (105), Expect = 2e-04
Identities = 55/264 (20%), Positives = 105/264 (39%), Gaps = 18/264 (6%)
Query: 298 PNEEEAFALEPIDITVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPT 357
P +EEA E VKE ++ + K LD K+ A+ + + D P
Sbjct: 725 PVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK 784
Query: 358 KKLMMWKETGGVEKLFS-LPAQPLWNNRLLKLFTRCLTPLVPED------LRKRRKGGEA 410
K + +E EK S L + + +P+ E+ +++ K E
Sbjct: 785 AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEE 844
Query: 411 DNLDEFLKEFENPEVPREDQQQQHQQRDVIDE---PIIEEPSRLQESVMEASRTNIDESA 467
+ K E + +E+ ++ + ++E P +E+P +ES +EA + ++
Sbjct: 845 EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP---KESKVEAKKEEAEDKK 901
Query: 468 MPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEK 527
P P + K E P ++ E + P + +EP + + E PEK+
Sbjct: 902 KVPTPEKEAPAKVEV--KEDAKPKEKTEVAKKEPDDAKAKEPSKPAE---KKEAAPEKKD 956
Query: 528 EKEKEKEDDEEEEDEDASGGDQDQ 551
KE++ + EE+ +A + D+
Sbjct: 957 TKEEKAKKPEEKPKTEAKAKEDDK 980
Score = 31.2 bits (69), Expect = 3.0
Identities = 14/32 (43%), Positives = 25/32 (78%), Gaps = 1/32 (3%)
Query: 520 ELLPEKEKE-KEKEKEDDEEEEDEDASGGDQD 550
E+ E+EKE KE+E +++E E+E+A GG+++
Sbjct: 469 EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE 500
Score = 29.6 bits (65), Expect = 8.8
Identities = 28/138 (20%), Positives = 58/138 (42%), Gaps = 6/138 (4%)
Query: 418 KEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNID-ESAMPPPPPQGV 476
+E ++PE + +++ + + P+ EE +++ +D +S P +
Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 773
Query: 477 KRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDD 536
R PE P + E + P +E PE E+ P+KE+ K KE++
Sbjct: 774 ARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA----PEKEI-PKKEEVKSPVKEEE 828
Query: 537 EEEEDEDASGGDQDQEER 554
+ +E + + +EE+
Sbjct: 829 KPQEVKVKEPPKKAEEEK 846
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 44.7 bits (104), Expect = 3e-04
Identities = 47/211 (22%), Positives = 93/211 (44%), Gaps = 34/211 (16%)
Query: 403 KRRKGGEA-----DNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVME 457
+R +G + D L++ ++ E RE Q++Q +Q++ E EE + +E+ E
Sbjct: 151 RRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKE--RERRAEERRKEREARRE 208
Query: 458 AS---RTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELP-PEEPPNIC 513
S RT ++ + K KA P PP+ E+ E+ P EE
Sbjct: 209 VSAHHRTMREDYSD--------KVKASHWSRSPPRPPR--ERFELGDGRKPVKEEKMEER 258
Query: 514 QLIPELELLPEKEKEKE-------------KEKEDDEEEEDEDASGGDQDQEERRWNKRT 560
L+ +L+ + + E++ +E+E++EEEE+E+ S ++ +EE +
Sbjct: 259 DLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 318
Query: 561 QQMLHGLQRALAKTGAESISLLELCRNTNRK 591
++ ++ AE +S E+ + R+
Sbjct: 319 EEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Score = 30.4 bits (67), Expect = 5.2
Identities = 35/158 (22%), Positives = 63/158 (39%), Gaps = 35/158 (22%)
Query: 413 LDEFLKEF-------ENPEVPR-EDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNID 464
LDE L+E E E+ R ++ + +RD ++E L++ ME + N
Sbjct: 13 LDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEE------GELRDHCMEITIRN-- 64
Query: 465 ESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPE 524
P ++ + + D + PPQQ+ + E V +E
Sbjct: 65 ---SPYRREDSMEDRGEEDDSLAIKPPQQMSRKE--KVHHRKDEK--------------R 105
Query: 525 KEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQ 562
KEK+ + KE + E E +QD+ R W ++ ++
Sbjct: 106 KEKKHARVKEKEREHERRKRHREEQDKARREWERQKRR 143
>gi|186928821 hepatoma-derived growth factor isoform c [Homo
sapiens]
Length = 233
Score = 44.3 bits (103), Expect = 3e-04
Identities = 41/166 (24%), Positives = 66/166 (39%), Gaps = 18/166 (10%)
Query: 399 EDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIE---------EPS 449
E K K + E L E EN + Q Q++ ++EP E +
Sbjct: 61 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 120
Query: 450 RLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVE------ 503
+ S E + IDE A +KR+AG + + P++ E E E
Sbjct: 121 NAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEV 180
Query: 504 ---LPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASG 546
LP E N P P +E+E+E+++E++ +ED +A G
Sbjct: 181 ERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPG 226
>gi|186928819 hepatoma-derived growth factor isoform b [Homo
sapiens]
Length = 256
Score = 44.3 bits (103), Expect = 3e-04
Identities = 41/166 (24%), Positives = 66/166 (39%), Gaps = 18/166 (10%)
Query: 399 EDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIE---------EPS 449
E K K + E L E EN + Q Q++ ++EP E +
Sbjct: 84 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 143
Query: 450 RLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVE------ 503
+ S E + IDE A +KR+AG + + P++ E E E
Sbjct: 144 NAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEV 203
Query: 504 ---LPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASG 546
LP E N P P +E+E+E+++E++ +ED +A G
Sbjct: 204 ERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPG 249
>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
Length = 240
Score = 44.3 bits (103), Expect = 3e-04
Identities = 41/166 (24%), Positives = 66/166 (39%), Gaps = 18/166 (10%)
Query: 399 EDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIE---------EPS 449
E K K + E L E EN + Q Q++ ++EP E +
Sbjct: 68 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 127
Query: 450 RLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVE------ 503
+ S E + IDE A +KR+AG + + P++ E E E
Sbjct: 128 NAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEV 187
Query: 504 ---LPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASG 546
LP E N P P +E+E+E+++E++ +ED +A G
Sbjct: 188 ERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPG 233
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 43.9 bits (102), Expect = 5e-04
Identities = 33/140 (23%), Positives = 69/140 (49%), Gaps = 19/140 (13%)
Query: 425 VPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMP-----PPPPQGVKRK 479
+P++ + ++R I + + E + ES+ + + E +P PPP + + +
Sbjct: 439 LPKKRPIYEDKKRKKIPQQL--ESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEE 496
Query: 480 ----AGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKED 535
AG D E + ++ E++E V + +E P E E+E+E+E E+ +
Sbjct: 497 DTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPE--------EEEEEEEEEEEDEESE 548
Query: 536 DEEEEDEDASGGDQDQEERR 555
+EEEE+ ++ G + D+E+ +
Sbjct: 549 EEEEEEGESEGSEGDEEDEK 568
Score = 43.1 bits (100), Expect = 8e-04
Identities = 45/218 (20%), Positives = 97/218 (44%), Gaps = 22/218 (10%)
Query: 402 RKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRT 461
R+R+K E LKE E E ++DQ +Q + + +E ++ + V+ AS
Sbjct: 238 RERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEE 297
Query: 462 NIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELEL 521
+ +G K+K ++ ++ E E ++ P+ + E
Sbjct: 298 KAETPTAAEDDNEGDKKK----------KDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA 347
Query: 522 LPEKEKEKEKEKEDDEEE----EDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAE 577
L + ++E+E++K ++EE E+ +A ++++ E+ +R +Q + L K G
Sbjct: 348 LAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEG-- 405
Query: 578 SISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEE 615
LL ++++A A+ + L L + Q +E+ ++
Sbjct: 406 --KLL----TKSQREARARAEATLKLLQAQGVEVPSKD 437
Score = 37.4 bits (85), Expect = 0.042
Identities = 46/191 (24%), Positives = 80/191 (41%), Gaps = 27/191 (14%)
Query: 386 LKLFTRCLTPLVPEDLRKRRKGGEA-DNLDEF-LKEFENPEVPREDQQQQHQQRDVIDEP 443
+K L L E+ R++R+ E L+E K E + +E ++++ Q+ E
Sbjct: 341 VKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKER 400
Query: 444 IIEEPSRLQESVMEASRTNIDESAMPPPPPQGV---------KRKAGQIDPEPVMPPQQV 494
+ +E L +S EA E+ + QGV K++ D + PQQ+
Sbjct: 401 LKKEGKLLTKSQREARARA--EATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQL 458
Query: 495 EQMEIPPVELPPEEPPNIC-------QLIPELELLPEKEKEKEKEKEDDEEEEDEDASGG 547
E E+ E +C Q +PE E P + +E+E +D +D +A
Sbjct: 459 ESKEV-------SESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMAS 511
Query: 548 DQDQEERRWNK 558
D++ E+ NK
Sbjct: 512 DEETEKVEGNK 522
Score = 31.6 bits (70), Expect = 2.3
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 11/115 (9%)
Query: 156 QENDFGDFGMDDREIMREGSAFEDDDMLVSTTTSNLLLESEQSTSNLNEKINHLEYEDQY 215
+E D D G+DD E M S E + + + + E+ E+ E E++
Sbjct: 494 EEEDTEDAGLDDWEAM--ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEE 551
Query: 216 KDDNFGEGNDGGILDDKLISNNDGG-IFDDPPALSEAGVMLPEQPAHDDMDEDDN 269
+++ EG++G D+K+ D G D P+ E + + D DD+
Sbjct: 552 EEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPS--------KEMSSDSEYDSDDD 598
Score = 29.6 bits (65), Expect = 8.8
Identities = 30/140 (21%), Positives = 58/140 (41%), Gaps = 18/140 (12%)
Query: 421 ENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGV---- 476
+ P+ + ++++ +++D ++ I++E L+E +EA D + P +
Sbjct: 35 QEPQKSKGKKKKEKKKQDFDEDDILKE---LEELSLEAQGIKADRETVAVKPTENNEEEF 91
Query: 477 ----KRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLI-----PELELLPEKEK 527
K+K GQ + E++E + P + + LP+K K
Sbjct: 92 TSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAK 151
Query: 528 EK--EKEKEDDEEEEDEDAS 545
K + K+ D EEDED S
Sbjct: 152 GKAQKSNKKWDGSEEDEDNS 171
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 43.5 bits (101), Expect = 6e-04
Identities = 39/165 (23%), Positives = 82/165 (49%), Gaps = 17/165 (10%)
Query: 406 KGGEADNLDEFLKEFEN--PEVP------REDQQQQHQQRDVIDEPIIEEPSRLQESVME 457
K EAD +KEFE+ P+V R+++++ ++ ++ ++ R +E V +
Sbjct: 581 KEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKD 640
Query: 458 ASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIP 517
R ++ P PP + K + P+ P ++ P LP P +L
Sbjct: 641 KGR---EDKMKAPAPPLVLPPKELAL---PLFSPATASRV---PAMLPSLLPVLPEKLFE 691
Query: 518 ELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQ 562
E E + EKEK+K+K+++ ++E++++ ++++E+R KR ++
Sbjct: 692 EKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKE 736
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 43.1 bits (100), Expect = 8e-04
Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 22/136 (16%)
Query: 419 EFENPEVPREDQQQQHQ-QRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVK 477
+ + P+V + QH+ ++I+E +E+ ++S ME + T I E + + K
Sbjct: 435 KIQKPKVEAPKLKVQHKFVEEIIEETKVED----EKSEMEEALTAITEE-LAVSMKEEKK 489
Query: 478 RKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDE 537
A + + EP ++V + P PE KE+E EKE+E+ +
Sbjct: 490 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEV----------------KEEEGEKEEEEGQ 533
Query: 538 EEEDEDASGGDQDQEE 553
EEE+E+ G DQ E
Sbjct: 534 EEEEEEDEGAKSDQAE 549
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/148 (17%), Positives = 73/148 (49%), Gaps = 13/148 (8%)
Query: 423 PEVPREDQQQQHQQRDVIDE----PIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKR 478
P+ P E++ + + ++E P+ + P +++ ++ ++E+ +G ++
Sbjct: 644 PKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVE-EKAKSPVPKSPVEEAKSKAEVGKGEQK 702
Query: 479 KAGQIDPEPVMPPQQVEQMEIPPVELPPE---EPPNICQLIPELELLPEK-----EKEKE 530
+ + + + ++VE+ E P ++P + E P + + E+ + + EKE +
Sbjct: 703 EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETK 762
Query: 531 KEKEDDEEEEDEDASGGDQDQEERRWNK 558
+E + ++E++++ +GG+ EE +K
Sbjct: 763 EEGKPLQQEKEKEKAGGEGGSEEEGSDK 790
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 43.1 bits (100), Expect = 8e-04
Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 22/136 (16%)
Query: 419 EFENPEVPREDQQQQHQ-QRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVK 477
+ + P+V + QH+ ++I+E +E+ ++S ME + T I E + + K
Sbjct: 59 KIQKPKVEAPKLKVQHKFVEEIIEETKVED----EKSEMEEALTAITEE-LAVSMKEEKK 113
Query: 478 RKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDE 537
A + + EP ++V + P PE KE+E EKE+E+ +
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEV----------------KEEEGEKEEEEGQ 157
Query: 538 EEEDEDASGGDQDQEE 553
EEE+E+ G DQ E
Sbjct: 158 EEEEEEDEGAKSDQAE 173
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/148 (17%), Positives = 73/148 (49%), Gaps = 13/148 (8%)
Query: 423 PEVPREDQQQQHQQRDVIDE----PIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKR 478
P+ P E++ + + ++E P+ + P +++ ++ ++E+ +G ++
Sbjct: 268 PKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVE-EKAKSPVPKSPVEEAKSKAEVGKGEQK 326
Query: 479 KAGQIDPEPVMPPQQVEQMEIPPVELPPE---EPPNICQLIPELELLPEK-----EKEKE 530
+ + + + ++VE+ E P ++P + E P + + E+ + + EKE +
Sbjct: 327 EEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETK 386
Query: 531 KEKEDDEEEEDEDASGGDQDQEERRWNK 558
+E + ++E++++ +GG+ EE +K
Sbjct: 387 EEGKPLQQEKEKEKAGGEGGSEEEGSDK 414
>gi|7657455 pescadillo homolog 1, containing BRCT domain [Homo
sapiens]
Length = 588
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/140 (23%), Positives = 68/140 (48%), Gaps = 14/140 (10%)
Query: 468 MPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEK 527
+PP V K G +PP++++ + + E+P N+ + E E +
Sbjct: 419 LPPHLSPFVTEKEGDY-----VPPEKLKLLALQR----GEDPGNLNESEEEEE--EDDNN 467
Query: 528 EKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLELCRN 587
E + ++E + EEE+EDA G + +EE R +Q + G + + A ++ L + R
Sbjct: 468 EGDGDEEGENEEEEEDAEAGSEKEEEARLAALEEQRMEGKK---PRVMAGTLKLEDKQRL 524
Query: 588 TNRKQAAAKFYSFLVLKKQQ 607
+++ AK + +++KK++
Sbjct: 525 AQEEESEAKRLAIMMMKKRE 544
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/140 (26%), Positives = 63/140 (45%), Gaps = 26/140 (18%)
Query: 423 PEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQ 482
PEVP++ ++ + P+ ++ V E + + E +P P P+ V+ +
Sbjct: 10005 PEVPKKPVPEEK-----VPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAK 10059
Query: 483 ID------------PEPV-----MPPQQVEQMEIP---PVELPPEEPPNI-CQLIPELEL 521
+ P PV PP +V + P PV LP EE +++PE E+
Sbjct: 10060 VPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEV 10119
Query: 522 LPEKEKEKEKEKEDDEEEED 541
LPE+E+ +E+E EEE+
Sbjct: 10120 LPEEEEVLPEEEEVLPEEEE 10139
Score = 39.7 bits (91), Expect = 0.009
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 19/132 (14%)
Query: 423 PEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQ 482
PEVP++ ++ + P ++ V E + I E P P P+ V+ +
Sbjct: 10033 PEVPKKPVPEKK-----VPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPK 10087
Query: 483 ID------PEPVMPPQQVE---QMEIPPVE--LPPEEP--PNICQLIP-ELELLPEKEKE 528
+ P PV PQ+ E + EI P E LP EE P +++P E E+LPE+E+
Sbjct: 10088 VPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEI 10147
Query: 529 KEKEKEDDEEEE 540
+E+E EEE
Sbjct: 10148 PPEEEEVPPEEE 10159
Score = 38.9 bits (89), Expect = 0.015
Identities = 30/104 (28%), Positives = 55/104 (52%), Gaps = 11/104 (10%)
Query: 443 PIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQV--EQMEIP 500
P ++P+ + + V EA + + P P P + ++ + E ++P ++V E+ E+
Sbjct: 10069 PEEKKPTPVPKKV-EAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVL 10127
Query: 501 PVE---LPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEED 541
P E LP EE +++PE E +P +E+E E+E EEE+
Sbjct: 10128 PEEEEVLPEEE-----EVLPEEEEIPPEEEEVPPEEEYVPEEEE 10166
Score = 38.9 bits (89), Expect = 0.015
Identities = 63/313 (20%), Positives = 119/313 (38%), Gaps = 59/313 (18%)
Query: 256 PEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMPTMTDQTTLVPN----EEEAFA------ 305
PE P + +E + V++ + P + EP P Q T+ P E++A A
Sbjct: 10658 PESPPPEVFEEPEEVAL---EEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP 10714
Query: 306 -LEPIDI--TVKETKAKRKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMM 362
L P+ + KE ++K L+V E + ++ P K +
Sbjct: 10715 ELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPE---------VPKEVVPEKKVAVP 10765
Query: 363 WKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFEN 422
K K+ +P +P+ + P VP R E +E
Sbjct: 10766 KKPEVPPAKVPEVPKKPVLEEK----------PAVPVPERAESPPPEV---------YEE 10806
Query: 423 PEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMP------PPPPQGV 476
PE +++ ++ + EEP +V E + I E +P PPP+
Sbjct: 10807 PEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPK-- 10864
Query: 477 KRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDD 536
+ +PE V+ +++ PP PP+E ++ + I +L+ +P+K+ ++ + +
Sbjct: 10865 -----EPEPEKVIEKPKLKPRPPPPPPAPPKE--DVKEKIFQLKAIPKKKVPEKPQVPEK 10917
Query: 537 EEEEDEDASGGDQ 549
E GG++
Sbjct: 10918 VELTPLKVPGGEK 10930
Score = 38.1 bits (87), Expect = 0.025
Identities = 67/319 (21%), Positives = 130/319 (40%), Gaps = 53/319 (16%)
Query: 253 VMLPEQPAHDDMDEDDNVSMGGPDSPDSVDPVEPMP----------TMTDQTTLVPNEEE 302
V + E+P + + E++ P+ P S++ VE + + + T VP + E
Sbjct: 10235 VEVTEEPEEEPISEEEI-----PEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVE 10289
Query: 303 AFALEPIDITVKETKAK-----RKRKLIVDSVKELDSKTIRAQLSDYSDIVTTLDLAPPT 357
A P ++ K + K +K++ V E+ K ++ +V + PP
Sbjct: 10290 A---PPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKV-----LVPKKEAVPPA 10341
Query: 358 KKLMMWKETGGVEKLFSLPAQPLWNNRLLKLFTRCLTPLVPED-----LRKRRKGGEADN 412
K + +E V + + + RL +PE+ + + + GE
Sbjct: 10342 KGRTVLEEKVSV----AFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHE 10397
Query: 413 LDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPP-- 470
++EF+K E V E++ + + VI+ EE ++ I E +PP
Sbjct: 10398 VEEFIK-LEQHRV--EEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKK 10454
Query: 471 PPPQGVKRKAGQID----PEPVMPPQQV---EQMEIPPVELPPEEPPNICQLIPE--LEL 521
PP + V RK P+ ++ ++V E+ +PP ++P PP +++PE + +
Sbjct: 10455 PPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPK--EVVPEKKVPV 10512
Query: 522 LPEKEKEKEKEKEDDEEEE 540
P K+ E K + +E
Sbjct: 10513 PPAKKPEAPPPKVPEAPKE 10531
Score = 37.7 bits (86), Expect = 0.032
Identities = 35/157 (22%), Positives = 73/157 (46%), Gaps = 27/157 (17%)
Query: 397 VPEDLRKRRKGGEADNLDEFLKEFENPEVP--REDQQQQHQQRDVIDEPIIEEPSR--LQ 452
VP+ + R A+ + +E E + RE+++++ ++ +V + ++EEP ++
Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537
Query: 453 ESV------MEASRTNIDE-------------SAMPPPPPQGVKRKAGQIDPEPVMPPQQ 493
E + +EA + E + + PPP V +I PE +P
Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPV 9597
Query: 494 VEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKE 530
++ ++PP ++ PEEP + +PE ++ P+ K +E
Sbjct: 9598 PKKEKVPPPKV-PEEPK---KPVPEKKVPPKVIKMEE 9630
Score = 37.4 bits (85), Expect = 0.042
Identities = 33/125 (26%), Positives = 63/125 (50%), Gaps = 22/125 (17%)
Query: 423 PEVPREDQQQQ---HQQRDVIDEPIIEEPSR--LQESVMEASRTNIDE--SAMPPPPPQG 475
PEVP++ ++++ ++ +V+ + EEP + E + +I+E PP P+
Sbjct: 10213 PEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEV 10272
Query: 476 VKRKAGQIDPEPV-----MPPQQV------EQMEIP--PVELPPEEPPNICQLIPELE-L 521
+K+ + P PV PP +V E++ +P E PP + P + + +PE + L
Sbjct: 10273 IKKAVPEA-PTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVL 10331
Query: 522 LPEKE 526
+P+KE
Sbjct: 10332 VPKKE 10336
Score = 35.8 bits (81), Expect = 0.12
Identities = 31/121 (25%), Positives = 53/121 (43%), Gaps = 16/121 (13%)
Query: 423 PEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQ 482
PEVP ++ +++ P ++P V EA + + E +P PPP+
Sbjct: 10579 PEVPEAPKEVVPEKKVPAAPP--KKPEVTPVKVPEAPKEVVPEKKVPVPPPK-------- 10628
Query: 483 IDPEPVMPPQQVEQME---IPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEE 539
+P +PP +V ++ +P ++P PP PE+ PE+ +E E EE
Sbjct: 10629 ---KPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEP 10685
Query: 540 E 540
E
Sbjct: 10686 E 10686
Score = 35.4 bits (80), Expect = 0.16
Identities = 28/125 (22%), Positives = 55/125 (44%), Gaps = 7/125 (5%)
Query: 423 PEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQ 482
PEVP+ ++ + E I +P V EA + + E +P PP+ + +
Sbjct: 10554 PEVPKAAVPEKK-----VPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVK 10608
Query: 483 ID--PEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEE 540
+ P+ V+P ++V E+PP + P + ++ + +PE K + + EE
Sbjct: 10609 VPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE 10668
Query: 541 DEDAS 545
E+ +
Sbjct: 10669 PEEVA 10673
Score = 35.0 bits (79), Expect = 0.21
Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 21/110 (19%)
Query: 433 QHQQRDVIDEPIIEEPSRLQE----SVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPV 488
+ Q++ ++ +P I P++++E V EA + + E +P P P+ K ++ EP
Sbjct: 9556 ERQEKKIVLKPKI--PAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPK 9613
Query: 489 MPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEE 538
P V + ++PP + EEP LP K E+ + +E+
Sbjct: 9614 KP---VPEKKVPPKVIKMEEP------------LPAKVTERHMQITQEEK 9648
Score = 34.3 bits (77), Expect = 0.36
Identities = 38/149 (25%), Positives = 68/149 (45%), Gaps = 24/149 (16%)
Query: 421 ENPEVPREDQQQQHQQRDVIDE-----PIIEEPSRLQESVMEASRTNIDESAMP------ 469
E EV E+++ ++ +V+ E P EE +E V E +E +P
Sbjct: 10122 EEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV 10181
Query: 470 --PPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQ----LIPELELLP 523
P P +K+K + + V+P ++ E PP ++P E P + + L E E+LP
Sbjct: 10182 PVPAPVPEIKKKV--TEKKVVIPKKE----EAPPAKVP-EVPKKVEEKRIILPKEEEVLP 10234
Query: 524 EKEKEKEKEKEDDEEEEDEDASGGDQDQE 552
+ E+ +E+ EEE E+ ++ +E
Sbjct: 10235 VEVTEEPEEEPISEEEIPEEPPSIEEVEE 10263
Score = 34.3 bits (77), Expect = 0.36
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 28/128 (21%)
Query: 423 PEVPREDQQQQHQQRDVIDEPIIEEPSRLQE-----SVMEASRTNIDESAMPPPPPQGVK 477
PEVP++ ++ + V +EP + P+++ E V+ + + + P PP V
Sbjct: 10470 PEVPKKIVVEEKVR--VPEEPRVP-PTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVP 10526
Query: 478 RKAGQIDPEPVMPPQQVEQMEIPPVELP-------------------PEEPPNICQLIPE 518
++ PE +P ++ E+PP ++P PE PP P+
Sbjct: 10527 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPK 10586
Query: 519 LELLPEKE 526
E++PEK+
Sbjct: 10587 -EVVPEKK 10593
Score = 34.3 bits (77), Expect = 0.36
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 15/123 (12%)
Query: 421 ENPEVPREDQQQ-------QHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPP 473
E P+VP + + + + R ++ E +P +E V+++ E P P
Sbjct: 10910 EKPQVPEKVELTPLKVPGGEKKVRKLLPE---RKPEPKEEVVLKSVLRKRPEEEEPKVEP 10966
Query: 474 QGVKRKAGQIDPEPVMPPQQVEQMEIPPV---ELPPEEPPNICQLIPELEL-LPEKEKEK 529
+ +++ PEP PP+ VE++E+P V E EP + ++ P + L PE + +
Sbjct: 10967 KKLEKVKKPAVPEPP-PPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKP 11025
Query: 530 EKE 532
E E
Sbjct: 11026 EAE 11028
Score = 33.9 bits (76), Expect = 0.47
Identities = 60/267 (22%), Positives = 109/267 (40%), Gaps = 36/267 (13%)
Query: 278 PDSVDPVEPMPT-MTDQTTLVPNEEEAFALEPIDITVKETKAKRK----RKLIVDSVKEL 332
P + EP+P +T++ + EE+ + +T KE K + K V K L
Sbjct: 9623 PKVIKMEEPLPAKVTERHMQITQEEKVL----VAVTKKEAPPKARVPEEPKRAVPEEKVL 9678
Query: 333 DSKTIRAQLSDYSDIVTTLDLAPPTKKLMMWKETGGVEKLFSLPA-----QPLWNNRLLK 387
K R + PP K K EK+ S+ A QP+ +++
Sbjct: 9679 KLKPKREE-------------EPPAKVTEFRKRVVKEEKV-SIEAPKREPQPIKEVTIME 9724
Query: 388 LFTRCLTPLVPEDLRKRRKGGEADNLDEF-LKEFENPEVPRE-DQQQQHQQRDVIDEPII 445
R T + E+ ++ E + +E+ KEFE E E DQ +++++R+ E
Sbjct: 9725 EKERAYT--LEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREY--ERYE 9780
Query: 446 EEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELP 505
E + E + E +P P + + PE +P ++++ PP ++
Sbjct: 9781 EHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKV- 9839
Query: 506 PEEPPNICQLIPELELLPEKEKEKEKE 532
PEEP + + + + ++EKE+ E
Sbjct: 9840 PEEPKKVFEEKIRIS-ITKREKEQVTE 9865
Score = 33.9 bits (76), Expect = 0.47
Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 439 VIDEP--IIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQ 496
V +EP + EE R+ + E + + +P P + V + + + V PP +V +
Sbjct: 9839 VPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPE 9898
Query: 497 MEIPPVELPPEEPPNICQLIPELE--LLPEKEKEKEKEKEDDEEEE 540
+ P EL PEE +++ +E L+ E+E+ +E+E EEE
Sbjct: 9899 V---PKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEE 9941
Score = 33.1 bits (74), Expect = 0.80
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 11/81 (13%)
Query: 465 ESAMPPPPPQGVKRKAGQID-------PEPVMPPQQVEQMEIPPVELPPEEPPNICQLIP 517
E PPP V +KA + D P+ + P +++ + PP L P + P I +
Sbjct: 8973 EEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSS 9032
Query: 518 ELE----LLPEKEKEKEKEKE 534
+ E + ++KE +KEKE
Sbjct: 9033 KAEEVKIMTITRKKEVQKEKE 9053
Score = 33.1 bits (74), Expect = 0.80
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 11/124 (8%)
Query: 423 PEVPRE-DQQQQHQQRDV---IDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKR 478
PEVP+E + ++ + +V ++E ++EE +E + I E + P P V
Sbjct: 9897 PEVPKELEPEEVAFEEEVVTHVEEYLVEE----EEEYIHEEEEFITEEEVVPVIPVKVPE 9952
Query: 479 KAGQIDPEPVMPPQQVEQMEIPPVELP--PEEP-PNICQLIPELELLPEKEKEKEKEKED 535
+ PE P ++ E PP ++P P++P + LIP+ E P + + +K
Sbjct: 9953 VPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPV 10012
Query: 536 DEEE 539
EE+
Sbjct: 10013 PEEK 10016
Score = 32.3 bits (72), Expect = 1.4
Identities = 32/151 (21%), Positives = 59/151 (39%), Gaps = 36/151 (23%)
Query: 423 PEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMP---PP----PPQG 475
P+VP ++ +++ + P ++P V E + + E +P PP PP
Sbjct: 10523 PKVPEAPKEVVPEKKVPVPPP--KKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPE 10580
Query: 476 VKRKAGQIDPEPVMPPQQVEQMEIPPVELP-------------------PEEPPNICQLI 516
V ++ PE +P ++ E+ PV++P PE PP +
Sbjct: 10581 VPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEV 10640
Query: 517 PEL--------ELLPEKEKEKEKEKEDDEEE 539
P++ E +P K + E ++ EE
Sbjct: 10641 PKVAVPEKKVPEAIPPKPESPPPEVFEEPEE 10671
Score = 32.0 bits (71), Expect = 1.8
Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 9/60 (15%)
Query: 485 PEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDA 544
P P MP + V EIPPV PP IP L PE++K K E ++ +DA
Sbjct: 8943 PIPTMPIRAVPPEEIPPVVAPP---------IPLLLPTPEEKKPPPKRIEVTKKAVKKDA 8993
Score = 31.2 bits (69), Expect = 3.0
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 84 KIKMAFRPGVV---DLPEENREAAYNAITLPEEFHDFDQPLPDLDDIDVAQQFSLNQSRV 140
K+ +AFR VV L E EA I EEFH+ ++ + + +V + L Q RV
Sbjct: 10350 KVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRV 10409
Query: 141 EEITMREEVGNI 152
EE E+V +
Sbjct: 10410 EEEHRVEKVHRV 10421
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/82 (28%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Query: 482 QIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEED 541
++DP+ + +++E + + I +L +L++ +KE++KE EK + EE+ED
Sbjct: 633 KLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDED 692
Query: 542 EDASGGDQDQEERRWNKRTQQM 563
+D D +EE R KR +++
Sbjct: 693 DDRKSEDDKEEEER--KRQEEI 712
Score = 32.0 bits (71), Expect = 1.8
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 10/56 (17%)
Query: 516 IPELELLPEKEKEKEKEKEDDEEEEDED----------ASGGDQDQEERRWNKRTQ 561
+PE E EK+K+ +K++ D++EE +D SG D+D++E R ++ +
Sbjct: 793 LPEKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKE 848
Score = 29.6 bits (65), Expect = 8.8
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 11/47 (23%)
Query: 524 EKEKEKEKEKEDDEEEED-----------EDASGGDQDQEERRWNKR 559
+++K K+ K+DDE EED E+A + D++E KR
Sbjct: 847 KEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKR 893
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 36/153 (23%)
Query: 403 KRRKGGEADNLDEFLKEFENPEVPREDQQQQ--HQQRDVIDEPIIEEPSRLQESVMEASR 460
K RK G NL + PE P E +Q +Q++ + P R++E V E
Sbjct: 1263 KERKTGFKLNL------YTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGE 1316
Query: 461 TNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELE 520
+ PQ R+ P + P P E+P + +L
Sbjct: 1317 ALL---------PQEENRREETCAP-------------VSPNTSPGEKPED------DLI 1348
Query: 521 LLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEE 553
E+E+E+E+E+E++EEEE E+ GG +++
Sbjct: 1349 KPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKD 1381
Score = 38.1 bits (87), Expect = 0.025
Identities = 17/58 (29%), Positives = 34/58 (58%)
Query: 522 LPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESI 579
L ++ E+E+E+ED+EEEE+E+ D+++EE + ++ + L K + +I
Sbjct: 1064 LSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAI 1121
Score = 37.4 bits (85), Expect = 0.042
Identities = 17/48 (35%), Positives = 31/48 (64%)
Query: 506 PEEPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEE 553
PE P + LEL E +E+E+E++++EEEE+E+ ++++EE
Sbjct: 1049 PESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEE 1096
Score = 36.6 bits (83), Expect = 0.072
Identities = 16/46 (34%), Positives = 31/46 (67%)
Query: 508 EPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEE 553
E + +L E E+E+++E+E+E++EEEEDE+ ++++EE
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEE 1102
Score = 32.7 bits (73), Expect = 1.0
Identities = 12/43 (27%), Positives = 28/43 (65%)
Query: 520 ELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQ 562
+LL ++ E+E+E+++EEE+E+ ++D+EE + ++
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEE 1102
Score = 31.6 bits (70), Expect = 2.3
Identities = 13/47 (27%), Positives = 27/47 (57%)
Query: 522 LPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQ 568
L E KE +E+E++E+EE+E+ +++ EE + ++ +Q
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 41.6 bits (96), Expect = 0.002
Identities = 59/252 (23%), Positives = 102/252 (40%), Gaps = 39/252 (15%)
Query: 384 RLLKLFTRCLTPLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEP 443
R K+++R P E R+R++ E E +++ E QQ++ Q+RD +
Sbjct: 715 RQSKVYSR---PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQW 771
Query: 444 IIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVE 503
EE S E R + SA PP Q ++ + QQ EQ +P E
Sbjct: 772 QAEEKS-------ERGRQRL--SARPPLREQRERQLRAE-------ERQQREQRFLPEEE 815
Query: 504 LPPE------EPPNICQLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRW- 556
+ E Q + E E L +E+ ++ ++E+D +ED++ + + +++W
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Query: 557 ------NKRTQQMLH---GLQRALAK----TGAESISLLELCRNTNRKQAAAKFYSFLVL 603
KR + L+ LQ L K E L R R+Q + Y
Sbjct: 876 WQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ 935
Query: 604 KKQQAIELTQEE 615
+Q+ +L +EE
Sbjct: 936 LQQEEEQLLREE 947
Score = 41.2 bits (95), Expect = 0.003
Identities = 52/223 (23%), Positives = 103/223 (46%), Gaps = 18/223 (8%)
Query: 395 PLVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQES 454
P + E LRK ++ + + +E L+ E + R++Q++Q+++ + + + EE L+E
Sbjct: 893 PALQEQLRKEQQLLQEE--EEELQREEREKRRRQEQERQYREEEQLQQ---EEEQLLRE- 946
Query: 455 VMEASRTNIDESAMPPPPPQGVKRKAGQI-DPEPVMPPQQVEQMEIPPVELPPEEPPNIC 513
E + E + +++K Q+ EP +Q + + E +E +
Sbjct: 947 --EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL- 1003
Query: 514 QLIPELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAK 573
L E E +E E++ K+D+ ++E+E +++E+RR +R +Q R +
Sbjct: 1004 -LREEREKRRRQEWERQYRKKDELQQEEEQLLR--EEREKRRLQERERQY-----REEEE 1055
Query: 574 TGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEP 616
E LL R T R+Q + Y +Q+ +L +EEP
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Score = 39.3 bits (90), Expect = 0.011
Identities = 51/225 (22%), Positives = 94/225 (41%), Gaps = 32/225 (14%)
Query: 401 LRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASR 460
L+ RR+ + + ++ E R Q++Q Q+R++ + EE S QE + + R
Sbjct: 110 LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEG---EEQSEKQERLEQRDR 166
Query: 461 TNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELE 520
DE +R+ Q E +Q++ + E P+E + + E
Sbjct: 167 QRRDEELWR-------QRQEWQEREERRAEEEQLQSCKGHETEEFPDE-----EQLRRRE 214
Query: 521 LLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRT----------QQMLHGLQRA 570
LL + K +E++++ E +D Q++EE+ W KR Q+ QR
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVF----QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 571 LAKTGAESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEE 615
L + E L +L R R++ + L+++Q + QEE
Sbjct: 271 LQE---EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Score = 38.5 bits (88), Expect = 0.019
Identities = 52/216 (24%), Positives = 95/216 (43%), Gaps = 18/216 (8%)
Query: 402 RKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRT 461
+K R+ E +E L E + R++ ++Q++++D + + EE L+E E +
Sbjct: 988 KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ---EEEQLLRE---EREKR 1041
Query: 462 NIDESAMPPPPPQGVKRKAGQI--DPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPEL 519
+ E + ++++ Q+ + Q++E+ EL EE QL+ E
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE----QLLREE 1097
Query: 520 ELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESI 579
PEK + +E+E++ EEEE + +Q E R KR +Q L R + E
Sbjct: 1098 ---PEKRRRQERERQCREEEELQQEE--EQLLREER-EKRRRQELERQYREEEEVQQEEE 1151
Query: 580 SLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEE 615
LL R+Q + Y +Q+ +L +EE
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Score = 34.3 bits (77), Expect = 0.36
Identities = 42/217 (19%), Positives = 94/217 (43%), Gaps = 10/217 (4%)
Query: 399 EDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEA 458
++ R++R E + ++LK E E +++++Q +RD +E E +L+E
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ-EEERRERWLKLEEEERRE 498
Query: 459 SRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPE 518
+ ++ + +R Q + E + + EQ +L E+ QL+
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ------QLRREQEERREQLLKR 552
Query: 519 LELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAES 578
E EK E+E+ ++ + E++E + +EERR + ++ L++ L + E
Sbjct: 553 EE---EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 579 ISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEE 615
+ E +++ + +LK ++ E Q++
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Score = 33.1 bits (74), Expect = 0.80
Identities = 48/220 (21%), Positives = 93/220 (42%), Gaps = 17/220 (7%)
Query: 402 RKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRT 461
R+R++ D+ L++ E + E ++++ Q+R E E LQ+ + R
Sbjct: 951 RRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER----EKKYREEEELQQEEEQLLRE 1006
Query: 462 NIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQ-----LI 516
++ Q K+ Q + E ++ ++ E+ + E E + Q L
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREER-EKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 517 PELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGA 576
E E +E E++ KE++ ++E+E ++ E+RR +R +Q R +
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLR--EEPEKRRRQERERQC-----REEEELQQ 1118
Query: 577 ESISLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQEEP 616
E LL R R+Q + Y +Q+ +L +EEP
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158
Score = 33.1 bits (74), Expect = 0.80
Identities = 39/212 (18%), Positives = 88/212 (41%), Gaps = 26/212 (12%)
Query: 414 DEFLKEFENPEVPRED------QQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESA 467
++ L+E E ++ R++ +++Q +R + ++E +L+ +E R +E
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE--RKFREEEQ 1730
Query: 468 MPPPPPQGVKRKAGQ----IDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELELLP 523
+ Q R+ + ++ E + P ++ +Q+ + E + Q E +L
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRS 1790
Query: 524 EKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESISLLE 583
++ K +E+E +E +E Q + RW + Q+ QR
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR-------------- 1836
Query: 584 LCRNTNRKQAAAKFYSFLVLKKQQAIELTQEE 615
L + +R+ A + ++ +++ EL QEE
Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQELWQEE 1868
Score = 32.3 bits (72), Expect = 1.4
Identities = 44/215 (20%), Positives = 96/215 (44%), Gaps = 23/215 (10%)
Query: 406 KGGEADNL--DEFLKEFENPEVPR----EDQQQQHQQRDVIDEPIIEEPSRLQESVMEAS 459
KG E + +E L+ E E+ R E QQQ+ +++D + + E+ R +E+V+
Sbjct: 197 KGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE 256
Query: 460 RTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPEL 519
+ E PQ +++ Q + E + +++E+ E+ E+ +L E
Sbjct: 257 EEKLQEEE-----PQ--RQRELQEEEEQL---RKLERQELRRERQEEEQQQQ--RLRREQ 304
Query: 520 ELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRTQQMLHGLQRALAKTGAESI 579
+L + K++E+ +++EE + + QEERR + ++ ++ L + E
Sbjct: 305 QL-----RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 580 SLLELCRNTNRKQAAAKFYSFLVLKKQQAIELTQE 614
+L R ++ + L+++Q + Q+
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
Score = 32.3 bits (72), Expect = 1.4
Identities = 34/168 (20%), Positives = 75/168 (44%), Gaps = 12/168 (7%)
Query: 399 EDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEA 458
E+ R+ ++ L +E + R++++++ QQR ++ + E +E +++
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 459 SRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIP- 517
E Q +KR+ + + + ++ Q L E+ + Q +
Sbjct: 553 EEEKRLEQERRE---QRLKREQEERRDQLLKREEERRQQR-----LKREQEERLEQRLKR 604
Query: 518 -ELELLPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWN--KRTQQ 562
E+E L ++E+ +++ K ++ EEE ++QEERR +R QQ
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Score = 31.2 bits (69), Expect = 3.0
Identities = 35/149 (23%), Positives = 68/149 (45%), Gaps = 8/149 (5%)
Query: 421 ENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRTNIDESAMPPPPPQGVKRKA 480
E E RE Q+++ QQ + ++ + E +E + + + Q +R+
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE-ERREQQLRREQEEERRE 374
Query: 481 GQIDPEPVMPPQQV---EQMEIPPVELPPEEP-PNICQLIPELELLPEKE--KEKEKEKE 534
Q+ E + +Q EQ +L E+ QL E +L E++ +E+E+E+
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 535 DDEEEEDEDASGGDQDQEERR-WNKRTQQ 562
+ + E++ ++QEERR W KR ++
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEE 463
Score = 30.4 bits (67), Expect = 5.2
Identities = 36/152 (23%), Positives = 66/152 (43%), Gaps = 19/152 (12%)
Query: 396 LVPEDLRKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPII-EEPSRLQES 454
L E +R K + + D+ LK E R Q+ + +Q + +++ + EE RL++
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEE----RRQQRLKREQEERLEQRLKREEVERLEQE 613
Query: 455 VMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQV--EQMEIPPVELPPEEPPNI 512
R +E P + +++ + + + QQ+ EQ E L EE
Sbjct: 614 ERREQRLKREE------PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE- 666
Query: 513 CQLIPELELLPEKEKEKEKEKEDDEEEEDEDA 544
LE ++E E+E+ +++ EEE E A
Sbjct: 667 -----RLEQRLKREHEEERREQELAEEEQEQA 693
Score = 30.4 bits (67), Expect = 5.2
Identities = 33/159 (20%), Positives = 70/159 (44%), Gaps = 15/159 (9%)
Query: 402 RKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRT 461
R+ RK E +E L E + R+++++Q ++ + + + EE L+E + R
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ---EEEQLLREEREKRRRQ 1134
Query: 462 NIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIPELEL 521
++ Q + + + +PE Q++E+ EL EE E
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEK-RRRQELERQYREEEELQQEE-----------EQ 1182
Query: 522 LPEKEKEKEKEKEDDEEEEDEDASGGDQDQEERRWNKRT 560
L +E+EK +++ + + E+E+ + Q R ++R+
Sbjct: 1183 LLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Score = 30.0 bits (66), Expect = 6.7
Identities = 40/177 (22%), Positives = 78/177 (44%), Gaps = 15/177 (8%)
Query: 396 LVPEDLRKRRKGGEADNLDEFLKEF-ENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQES 454
L E+ + R+ E L E +++ E E+ +E++Q ++R+ +E R +E
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 455 VMEASRTNIDESAMPPPPPQGVKRKAGQIDPEPVMPPQQV-----EQMEIPPVELPPEEP 509
+ + + E P + + + + + E +Q+ E+ +E E
Sbjct: 1086 LQQEEEQLLREE--PEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 510 PNICQLIPELELL---PEKEKEKEKEKEDDEEEE--DEDASGGDQDQEERRWNKRTQ 561
+ Q E +LL PEK + +E E++ EEEE E+ ++QE+RR + Q
Sbjct: 1144 EEVQQ--EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
>gi|4502805 chromogranin A precursor [Homo sapiens]
Length = 457
Score = 41.2 bits (95), Expect = 0.003
Identities = 38/161 (23%), Positives = 69/161 (42%), Gaps = 24/161 (14%)
Query: 402 RKRRKGGEADNLDEFLKEFENPEVPREDQQQQHQQRDVIDEPIIEEPSRLQESVMEASRT 461
++++ G D L E L E+Q Q + ++ ++EP ++ +E EA ++
Sbjct: 93 QQKKHSGFEDELSEVL----------ENQSSQAELKEAVEEPSSKDVMEKREDSKEAEKS 142
Query: 462 N-IDESAMP---PPPPQGVKRKAGQIDPEPVMPPQQVEQMEIPPVELPPEEPPNICQLIP 517
+ A P P P Q K + P ++ PP LP ++ P Q
Sbjct: 143 GEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNTHPPASLPSQKYPGP-QAEG 201
Query: 518 ELELLPEKEKEKEK---------EKEDDEEEEDEDASGGDQ 549
+ E L + ++EK K ++EEEE+E+A G++
Sbjct: 202 DSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEE 242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,798,449
Number of Sequences: 37866
Number of extensions: 1539759
Number of successful extensions: 24646
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 420
Number of HSP's successfully gapped in prelim test: 515
Number of HSP's that attempted gapping in prelim test: 12734
Number of HSP's gapped (non-prelim): 7280
length of query: 631
length of database: 18,247,518
effective HSP length: 108
effective length of query: 523
effective length of database: 14,157,990
effective search space: 7404628770
effective search space used: 7404628770
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.