BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] (499 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 1023 0.0 gi|23312374 protein phosphatase with EF hand calcium-binding dom... 238 9e-63 gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo... 235 8e-62 gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor... 235 8e-62 gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo... 231 2e-60 gi|23312380 protein phosphatase with EF hand calcium-binding dom... 227 2e-59 gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] 221 2e-57 gi|215272354 protein phosphatase 3, catalytic subunit, beta isof... 214 1e-55 gi|215272352 protein phosphatase 3, catalytic subunit, beta isof... 214 1e-55 gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo... 214 1e-55 gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso... 212 6e-55 gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo... 212 6e-55 gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof... 210 3e-54 gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo... 210 3e-54 gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo... 209 6e-54 gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom... 209 6e-54 gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo... 207 2e-53 gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor... 207 2e-53 gi|183603929 protein phosphatase 6, catalytic subunit isoform a ... 206 5e-53 gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H... 206 5e-53 gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof... 205 9e-53 gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso... 203 3e-52 gi|183603931 protein phosphatase 6, catalytic subunit isoform c ... 175 1e-43 gi|23312378 protein phosphatase with EF hand calcium-binding dom... 171 2e-42 gi|23312386 serine/threonine protein phosphatase with EF-hand mo... 164 2e-40 gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 89 9e-18 gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly... 87 5e-17 gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 86 8e-17 gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly... 86 1e-16 gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly... 86 1e-16 >gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] Length = 499 Score = 1023 bits (2644), Expect = 0.0 Identities = 499/499 (100%), Positives = 499/499 (100%) Query: 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS 60 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS Sbjct: 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS 60 Query: 61 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 120 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE Sbjct: 61 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 120 Query: 121 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPK 180 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPK Sbjct: 121 TVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPK 180 Query: 181 LEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVC 240 LEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVC Sbjct: 181 LEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVC 240 Query: 241 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL 300 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL Sbjct: 241 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL 300 Query: 301 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG 360 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG Sbjct: 301 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG 360 Query: 361 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNL 420 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNL Sbjct: 361 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNL 420 Query: 421 DYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP 480 DYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP Sbjct: 421 DYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP 480 Query: 481 HPNVKPMAYANTLLQLGMM 499 HPNVKPMAYANTLLQLGMM Sbjct: 481 HPNVKPMAYANTLLQLGMM 499 >gi|23312374 protein phosphatase with EF hand calcium-binding domain 1 isoform 1b [Homo sapiens] Length = 625 Score = 238 bits (607), Expect = 9e-63 Identities = 129/353 (36%), Positives = 204/353 (57%), Gaps = 25/353 (7%) Query: 156 EHKRSVVDSLD-IESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILV 214 E ++ + D D ++S+ + D Y+GP+L+ +T + + L++ +K+Q+ LH ++L Sbjct: 86 ESEQDMRDRWDYVDSIDVPDSYNGPRLQF-PLTCTDIDLLLEAFKEQQILHAHYVLEVLF 144 Query: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274 + K+VL ++ ++++T+CGD HG+ DL IF NGLPSE NPY+FNGDFVD Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204 Query: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYT---AQMYELF 331 RG S+E+++ L L+YP+ HL RGNHE MN YGF E+ KY ++ ++ Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264 Query: 332 SEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQ-----PPDS-------- 378 E + WLP+ ++ ++L++HGG+ + L+ + ++ERN+ PP Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGI--SETTDLNLLHRVERNKMKSVLIPPTETNRDHDTD 322 Query: 379 ---GPMCDLLWSDPQPQNGRSISK-RGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGY 434 + D+LWSDP+ +NG + RG C FGPDVT L + L +IRSHE K EGY Sbjct: 323 SKHNKIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGY 382 Query: 435 EVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPM 487 E+ H G+ VT+FSA NY ++ N+ +YI L S P+F Q+ +P+ Sbjct: 383 EICHDGKVVTIFSASNYYEEGSNRGAYIKL-CSGTTPRFFQYQVTKATCFQPL 434 >gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform [Homo sapiens] Length = 309 Score = 235 bits (599), Expect = 8e-62 Identities = 122/296 (41%), Positives = 180/296 (60%), Gaps = 11/296 (3%) Query: 189 SFMKELMQWYK---DQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHG 245 +F KEL QW + + K+L+ + + KE+L+K S + E +TVCGD HG Sbjct: 5 AFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCP----VTVCGDVHG 60 Query: 246 QFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHE 305 QF+DL+ +F + G +TN Y+F GD+VDRG +SVE + L K+ YP+ +LRGNHE Sbjct: 61 QFHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHE 119 Query: 306 TDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLD 364 + + Q+YGF E KY A +++ F+++F++LPL ++G++ +HGGL S TLD Sbjct: 120 SRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGL-SPSIDTLD 178 Query: 365 DIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYII 424 IR ++R ++ P GPMCDLLWSDP + G IS RG FG D+++ F N L + Sbjct: 179 HIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVS 238 Query: 425 RSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP 480 R+H++ EGY H VT+FSAPNYC + GN+A+ + L + L+ F QF P Sbjct: 239 RAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDT-LKYSFLQFDPAP 293 >gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform [Homo sapiens] Length = 309 Score = 235 bits (599), Expect = 8e-62 Identities = 122/296 (41%), Positives = 180/296 (60%), Gaps = 11/296 (3%) Query: 189 SFMKELMQWYK---DQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHG 245 +F KEL QW + + K+L+ + + KE+L+K S + E +TVCGD HG Sbjct: 5 AFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCP----VTVCGDVHG 60 Query: 246 QFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHE 305 QF+DL+ +F + G +TN Y+F GD+VDRG +SVE + L K+ YP+ +LRGNHE Sbjct: 61 QFHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHE 119 Query: 306 TDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLD 364 + + Q+YGF E KY A +++ F+++F++LPL ++G++ +HGGL S TLD Sbjct: 120 SRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGL-SPSIDTLD 178 Query: 365 DIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYII 424 IR ++R ++ P GPMCDLLWSDP + G IS RG FG D+++ F N L + Sbjct: 179 HIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVS 238 Query: 425 RSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP 480 R+H++ EGY H VT+FSAPNYC + GN+A+ + L + L+ F QF P Sbjct: 239 RAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDT-LKYSFLQFDPAP 293 >gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform [Homo sapiens] Length = 309 Score = 231 bits (588), Expect = 2e-60 Identities = 121/295 (41%), Positives = 177/295 (60%), Gaps = 11/295 (3%) Query: 190 FMKELMQWYK---DQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQ 246 F KEL QW + + K+L + + KE+L+K S + E +TVCGD HGQ Sbjct: 6 FTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCP----VTVCGDVHGQ 61 Query: 247 FYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHET 306 F+DL+ +F + G +TN Y+F GD+VDRG +SVE + L K+ Y + +LRGNHE+ Sbjct: 62 FHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES 120 Query: 307 DNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDD 365 + Q+YGF E KY A +++ F+++F++LPL ++G++ +HGGL S TLD Sbjct: 121 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGL-SPSIDTLDH 179 Query: 366 IRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIR 425 IR ++R ++ P GPMCDLLWSDP + G IS RG FG D+++ F N L + R Sbjct: 180 IRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSR 239 Query: 426 SHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP 480 +H++ EGY H VT+FSAPNYC + GN+A+ + L + L+ F QF P Sbjct: 240 AHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDT-LKYSFLQFDPAP 293 >gi|23312380 protein phosphatase with EF hand calcium-binding domain 1 isoform 1 [Homo sapiens] Length = 653 Score = 227 bits (578), Expect = 2e-59 Identities = 129/379 (34%), Positives = 204/379 (53%), Gaps = 49/379 (12%) Query: 156 EHKRSVVDSLD-IESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILV 214 E ++ + D D ++S+ + D Y+GP+L+ +T + + L++ +K+Q+ LH ++L Sbjct: 86 ESEQDMRDRWDYVDSIDVPDSYNGPRLQF-PLTCTDIDLLLEAFKEQQILHAHYVLEVLF 144 Query: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274 + K+VL ++ ++++T+CGD HG+ DL IF NGLPSE NPY+FNGDFVD Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204 Query: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYT---AQMYELF 331 RG S+E+++ L L+YP+ HL RGNHE MN YGF E+ KY ++ ++ Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264 Query: 332 SEVFEWLPLAQCINGKVLIMHGGL------------------------------------ 355 E + WLP+ ++ ++L++HGG+ Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSK 324 Query: 356 FSEDGVTLDDIRKIERNRQPPDS------GPMCDLLWSDPQPQNGRSISK-RGVSCQFGP 408 ++ GVT + +I+ N P + + D+LWSDP+ +NG + RG C FGP Sbjct: 325 HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGP 384 Query: 409 DVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD 468 DVT L + L +IRSHE K EGYE+ H G+ VT+FSA NY ++ N+ +YI L S Sbjct: 385 DVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL-CSG 443 Query: 469 LRPQFHQFTAVPHPNVKPM 487 P+F Q+ +P+ Sbjct: 444 TTPRFFQYQVTKATCFQPL 462 >gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens] Length = 307 Score = 221 bits (562), Expect = 2e-57 Identities = 123/292 (42%), Positives = 173/292 (59%), Gaps = 12/292 (4%) Query: 206 RKCAYQILVQVKEVLSKLSTLV--ETTLKETEK-ITVCGDTHGQFYDLLNIFELNGLPSE 262 R+C +VK + +K ++ E+ ++ + +TVCGD HGQFYDL +F + G E Sbjct: 15 RRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPE 74 Query: 263 TNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAK 322 TN Y+F GDFVDRG +SVE L L K+ YPD L+RGNHE+ + Q+YGF E K Sbjct: 75 TN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRK 133 Query: 323 Y-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPM 381 Y + ++ +E+F++L L+ I+GK+ +HGGL S TLD IR I+R ++ P GPM Sbjct: 134 YGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGL-SPSIQTLDQIRTIDRKQEVPHDGPM 192 Query: 382 CDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGR 441 CDLLWSDP+ G +S RG FG DV F N++D I R+H++ EGY+ Sbjct: 193 CDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNET 252 Query: 442 CVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPH-----PNVKPMA 488 +TV+SAPNYC + GN A+ + L L+ F F A P P+ KP+A Sbjct: 253 VLTVWSAPNYCYRCGNVAAILELD-EHLQKDFIIFEAAPQETRGIPSKKPVA 303 >gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform c [Homo sapiens] Length = 515 Score = 214 bits (546), Expect = 1e-55 Identities = 119/294 (40%), Positives = 172/294 (58%), Gaps = 22/294 (7%) Query: 203 KLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSE 262 ++ + A +I+ + +L + T++E ITVCGD HGQF+DL+ +FE+ G P+ Sbjct: 64 RVDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDLMKLFEVGGSPAN 119 Query: 263 TNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAK 322 T Y+F GD+VDRG FS+E +L L+ K+LYP LLRGNHE ++ + + F+ E K K Sbjct: 120 TR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIK 178 Query: 323 YTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMC 382 Y+ ++YE E F+ LPLA +N + L +HGGL S + TLDDIR+++R ++PP GPMC Sbjct: 179 YSERVYEACMEAFDSLPLAALLNQQFLCVHGGL-SPEIHTLDDIRRLDRFKEPPAFGPMC 237 Query: 383 DLLWSDPQPQNGRSISK--------RGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGY 434 DLLWSDP G S+ RG S + FL+ NNL IIR+HE + GY Sbjct: 238 DLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGY 297 Query: 435 EVAHGGR------CVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHP 482 + + +T+FSAPNY D NKA+ + + + + QF PHP Sbjct: 298 RMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM--NIRQFNCSPHP 349 >gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform a [Homo sapiens] Length = 525 Score = 214 bits (546), Expect = 1e-55 Identities = 119/294 (40%), Positives = 172/294 (58%), Gaps = 22/294 (7%) Query: 203 KLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSE 262 ++ + A +I+ + +L + T++E ITVCGD HGQF+DL+ +FE+ G P+ Sbjct: 64 RVDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDLMKLFEVGGSPAN 119 Query: 263 TNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAK 322 T Y+F GD+VDRG FS+E +L L+ K+LYP LLRGNHE ++ + + F+ E K K Sbjct: 120 TR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIK 178 Query: 323 YTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMC 382 Y+ ++YE E F+ LPLA +N + L +HGGL S + TLDDIR+++R ++PP GPMC Sbjct: 179 YSERVYEACMEAFDSLPLAALLNQQFLCVHGGL-SPEIHTLDDIRRLDRFKEPPAFGPMC 237 Query: 383 DLLWSDPQPQNGRSISK--------RGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGY 434 DLLWSDP G S+ RG S + FL+ NNL IIR+HE + GY Sbjct: 238 DLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGY 297 Query: 435 EVAHGGR------CVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHP 482 + + +T+FSAPNY D NKA+ + + + + QF PHP Sbjct: 298 RMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM--NIRQFNCSPHP 349 >gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform b [Homo sapiens] Length = 524 Score = 214 bits (546), Expect = 1e-55 Identities = 119/294 (40%), Positives = 172/294 (58%), Gaps = 22/294 (7%) Query: 203 KLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSE 262 ++ + A +I+ + +L + T++E ITVCGD HGQF+DL+ +FE+ G P+ Sbjct: 64 RVDEEIALRIINEGAAILRREKTMIEVEAP----ITVCGDIHGQFFDLMKLFEVGGSPAN 119 Query: 263 TNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAK 322 T Y+F GD+VDRG FS+E +L L+ K+LYP LLRGNHE ++ + + F+ E K K Sbjct: 120 TR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIK 178 Query: 323 YTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMC 382 Y+ ++YE E F+ LPLA +N + L +HGGL S + TLDDIR+++R ++PP GPMC Sbjct: 179 YSERVYEACMEAFDSLPLAALLNQQFLCVHGGL-SPEIHTLDDIRRLDRFKEPPAFGPMC 237 Query: 383 DLLWSDPQPQNGRSISK--------RGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGY 434 DLLWSDP G S+ RG S + FL+ NNL IIR+HE + GY Sbjct: 238 DLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGY 297 Query: 435 EVAHGGR------CVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHP 482 + + +T+FSAPNY D NKA+ + + + + QF PHP Sbjct: 298 RMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM--NIRQFNCSPHP 349 >gi|194688147 protein phosphatase 3, catalytic subunit, alpha isoform isoform 2 [Homo sapiens] Length = 511 Score = 212 bits (540), Expect = 6e-55 Identities = 118/314 (37%), Positives = 177/314 (56%), Gaps = 25/314 (7%) Query: 183 DGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGD 242 DGK + +K + + +L A +I+ + +L + L++ +TVCGD Sbjct: 38 DGKPRVDILKAHLM---KEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGD 90 Query: 243 THGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRG 302 HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLRG Sbjct: 91 IHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149 Query: 303 NHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVT 362 NHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL E T Sbjct: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIN-T 208 Query: 363 LDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISK--------RGVSCQFGPDVTKAF 414 LDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + F Sbjct: 209 LDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEF 268 Query: 415 LEENNLDYIIRSHEVKAEGYEVAHGGR------CVTVFSAPNYCDQMGNKASYIHLQGSD 468 L+ NNL I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 269 LQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 328 Query: 469 LRPQFHQFTAVPHP 482 + QF PHP Sbjct: 329 M--NIRQFNCSPHP 340 >gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform isoform 1 [Homo sapiens] Length = 521 Score = 212 bits (540), Expect = 6e-55 Identities = 118/314 (37%), Positives = 177/314 (56%), Gaps = 25/314 (7%) Query: 183 DGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGD 242 DGK + +K + + +L A +I+ + +L + L++ +TVCGD Sbjct: 38 DGKPRVDILKAHLM---KEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGD 90 Query: 243 THGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRG 302 HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLRG Sbjct: 91 IHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149 Query: 303 NHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVT 362 NHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL E T Sbjct: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIN-T 208 Query: 363 LDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISK--------RGVSCQFGPDVTKAF 414 LDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + F Sbjct: 209 LDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEF 268 Query: 415 LEENNLDYIIRSHEVKAEGYEVAHGGR------CVTVFSAPNYCDQMGNKASYIHLQGSD 468 L+ NNL I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 269 LQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 328 Query: 469 LRPQFHQFTAVPHP 482 + QF PHP Sbjct: 329 M--NIRQFNCSPHP 340 >gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform 3 [Homo sapiens] Length = 341 Score = 210 bits (534), Expect = 3e-54 Identities = 103/222 (46%), Positives = 145/222 (65%), Gaps = 3/222 (1%) Query: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296 + +CGD HGQ+YDLL +FE G P E+N Y+F GD+VDRG S+E I L +K+ YP++ Sbjct: 70 LKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPEN 128 Query: 297 FHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLF 356 F LLRGNHE ++N+IYGF E K +Y ++++ F++ F LP+A ++ K+ HGGL Sbjct: 129 FFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL- 187 Query: 357 SEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFL 415 S D +++ IR+I R PD G +CDLLWSDP G + RGVS FG +V FL Sbjct: 188 SPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFL 247 Query: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGN 457 +++LD I R+H+V +GYE + VT+FSAPNYC + N Sbjct: 248 HKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDN 289 >gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform 1 [Homo sapiens] Length = 330 Score = 210 bits (534), Expect = 3e-54 Identities = 103/222 (46%), Positives = 145/222 (65%), Gaps = 3/222 (1%) Query: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296 + +CGD HGQ+YDLL +FE G P E+N Y+F GD+VDRG S+E I L +K+ YP++ Sbjct: 59 LKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPEN 117 Query: 297 FHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLF 356 F LLRGNHE ++N+IYGF E K +Y ++++ F++ F LP+A ++ K+ HGGL Sbjct: 118 FFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL- 176 Query: 357 SEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFL 415 S D +++ IR+I R PD G +CDLLWSDP G + RGVS FG +V FL Sbjct: 177 SPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFL 236 Query: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGN 457 +++LD I R+H+V +GYE + VT+FSAPNYC + N Sbjct: 237 HKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDN 278 >gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform [Homo sapiens] Length = 323 Score = 209 bits (531), Expect = 6e-54 Identities = 103/222 (46%), Positives = 145/222 (65%), Gaps = 3/222 (1%) Query: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296 + +CGD HGQ+YDLL +FE G P E+N Y+F GD+VDRG S+E I L +K+ YP++ Sbjct: 59 LKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPEN 117 Query: 297 FHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLF 356 F LLRGNHE ++N+IYGF E K +Y ++++ F++ F LP+A ++ K+ HGGL Sbjct: 118 FFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL- 176 Query: 357 SEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFL 415 S D +++ IR+I R PD G +CDLLWSDP G + RGVS FG +V FL Sbjct: 177 SPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFL 236 Query: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGN 457 +++LD I R+H+V +GYE + VT+FSAPNYC + N Sbjct: 237 HKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDN 278 >gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo sapiens] Length = 512 Score = 209 bits (531), Expect = 6e-54 Identities = 119/315 (37%), Positives = 176/315 (55%), Gaps = 25/315 (7%) Query: 182 EDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCG 241 E+GK + +K + + +L + A +I+ +L + T++E ITVCG Sbjct: 33 ENGKPKVDVLKNHLV---KEGRLEEEVALKIINDGAAILRQEKTMIEVDAP----ITVCG 85 Query: 242 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 301 D HGQF+DL+ +FE+ G PS T Y+F GD+VDRG FS+E +L L+ K+ +P LLR Sbjct: 86 DIHGQFFDLMKLFEVGGSPSNTR-YLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLR 144 Query: 302 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 361 GNHE ++ + F+ E + KY+ Q+Y+ E F+ LPLA +N + L +HGG+ S + Sbjct: 145 GNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGM-SPEIT 203 Query: 362 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRS--------ISKRGVSCQFGPDVTKA 413 +LDDIRK++R +PP GP+CDLLWSDP G + RG S + Sbjct: 204 SLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCE 263 Query: 414 FLEENNLDYIIRSHEVKAEGYEVAHGGRC------VTVFSAPNYCDQMGNKASYIHLQGS 467 FL+ NNL IIR+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 264 FLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENN 323 Query: 468 DLRPQFHQFTAVPHP 482 + QF PHP Sbjct: 324 VM--NIRQFNCSPHP 336 >gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform 1 [Homo sapiens] Length = 327 Score = 207 bits (526), Expect = 2e-53 Identities = 112/261 (42%), Positives = 158/261 (60%), Gaps = 11/261 (4%) Query: 206 RKCAYQILVQVKE-------VLSKLSTLVETTLKETEK-ITVCGDTHGQFYDLLNIFELN 257 R C +VQ+ E + S+ L + L E E + +CGD HGQ+ DLL +FE Sbjct: 19 RGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYG 78 Query: 258 GLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEG 317 G P E N Y+F GD+VDRG S+E I L +K+ YP++F LLRGNHE ++N+IYGF Sbjct: 79 GFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYD 137 Query: 318 EVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPD 377 E K ++ ++++ F++ F LP+A ++ K+ HGGL S D +++ IR+I R PD Sbjct: 138 ECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTDVPD 196 Query: 378 SGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEV 436 +G +CDLLWSDP G + RGVS FG DV FL ++LD I R+H+V +GYE Sbjct: 197 TGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEF 256 Query: 437 AHGGRCVTVFSAPNYCDQMGN 457 + VT+FSAPNYC + N Sbjct: 257 FAKRQLVTLFSAPNYCGEFDN 277 >gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1 [Homo sapiens] Length = 327 Score = 207 bits (526), Expect = 2e-53 Identities = 112/261 (42%), Positives = 158/261 (60%), Gaps = 11/261 (4%) Query: 206 RKCAYQILVQVKE-------VLSKLSTLVETTLKETEK-ITVCGDTHGQFYDLLNIFELN 257 R C +VQ+ E + S+ L + L E E + +CGD HGQ+ DLL +FE Sbjct: 19 RGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYG 78 Query: 258 GLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEG 317 G P E N Y+F GD+VDRG S+E I L +K+ YP++F LLRGNHE ++N+IYGF Sbjct: 79 GFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYD 137 Query: 318 EVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPD 377 E K ++ ++++ F++ F LP+A ++ K+ HGGL S D +++ IR+I R PD Sbjct: 138 ECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTDVPD 196 Query: 378 SGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEV 436 +G +CDLLWSDP G + RGVS FG DV FL ++LD I R+H+V +GYE Sbjct: 197 TGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEF 256 Query: 437 AHGGRCVTVFSAPNYCDQMGN 457 + VT+FSAPNYC + N Sbjct: 257 FAKRQLVTLFSAPNYCGEFDN 277 >gi|183603929 protein phosphatase 6, catalytic subunit isoform a [Homo sapiens] Length = 342 Score = 206 bits (523), Expect = 5e-53 Identities = 113/245 (46%), Positives = 150/245 (61%), Gaps = 4/245 (1%) Query: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296 +TVCGD HGQFYDL +F G +TN YIF GDFVDRG +S+E L K +PD Sbjct: 85 VTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKWPDR 143 Query: 297 FHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGL 355 LLRGNHE+ + Q+YGF E + KY A + ++VF+ L +A I+ ++L +HGGL Sbjct: 144 ITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGL 203 Query: 356 FSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFL 415 S D TLD IR IERN++ P G CDL+WSDP+ + +IS RG FG VT F+ Sbjct: 204 -SPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFV 262 Query: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQ 475 NNL I R+H++ EGY+ + VTV+SAPNYC + GN AS + + + R + Sbjct: 263 HINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTR-EPKL 321 Query: 476 FTAVP 480 F AVP Sbjct: 322 FRAVP 326 >gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo sapiens] Length = 305 Score = 206 bits (523), Expect = 5e-53 Identities = 113/245 (46%), Positives = 150/245 (61%), Gaps = 4/245 (1%) Query: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296 +TVCGD HGQFYDL +F G +TN YIF GDFVDRG +S+E L K +PD Sbjct: 48 VTVCGDIHGQFYDLCELFRTGGQVPDTN-YIFMGDFVDRGYYSLETFTYLLALKAKWPDR 106 Query: 297 FHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGL 355 LLRGNHE+ + Q+YGF E + KY A + ++VF+ L +A I+ ++L +HGGL Sbjct: 107 ITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGL 166 Query: 356 FSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFL 415 S D TLD IR IERN++ P G CDL+WSDP+ + +IS RG FG VT F+ Sbjct: 167 -SPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFV 225 Query: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQ 475 NNL I R+H++ EGY+ + VTV+SAPNYC + GN AS + + + R + Sbjct: 226 HINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTR-EPKL 284 Query: 476 FTAVP 480 F AVP Sbjct: 285 FRAVP 289 >gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform 2 [Homo sapiens] Length = 286 Score = 205 bits (521), Expect = 9e-53 Identities = 102/218 (46%), Positives = 142/218 (65%), Gaps = 3/218 (1%) Query: 241 GDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLL 300 GD HGQ+YDLL +FE G P E+N Y+F GD+VDRG S+E I L +K+ YP++F LL Sbjct: 19 GDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL 77 Query: 301 RGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDG 360 RGNHE ++N+IYGF E K +Y ++++ F++ F LP+A ++ K+ HGGL S D Sbjct: 78 RGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDL 136 Query: 361 VTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSISKRGVSCQFGPDVTKAFLEENN 419 +++ IR+I R PD G +CDLLWSDP G + RGVS FG +V FL +++ Sbjct: 137 QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD 196 Query: 420 LDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGN 457 LD I R+H+V +GYE + VT+FSAPNYC + N Sbjct: 197 LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDN 234 >gi|194688149 protein phosphatase 3, catalytic subunit, alpha isoform isoform 3 [Homo sapiens] Length = 469 Score = 203 bits (517), Expect = 3e-52 Identities = 112/292 (38%), Positives = 167/292 (57%), Gaps = 23/292 (7%) Query: 183 DGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGD 242 DGK + +K + + +L A +I+ + +L + L++ +TVCGD Sbjct: 38 DGKPRVDILKAHLM---KEGRLEESVALRIITEGASILRQEKNLLDIDAP----VTVCGD 90 Query: 243 THGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRG 302 HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLRG Sbjct: 91 IHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRG 149 Query: 303 NHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVT 362 NHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL E T Sbjct: 150 NHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIN-T 208 Query: 363 LDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISK--------RGVSCQFGPDVTKAF 414 LDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + F Sbjct: 209 LDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEF 268 Query: 415 LEENNLDYIIRSHEVKAEGYEVAHGGR------CVTVFSAPNYCDQMGNKAS 460 L+ NNL I+R+HE + GY + + +T+FSAPNY D NK + Sbjct: 269 LQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKVT 320 >gi|183603931 protein phosphatase 6, catalytic subunit isoform c [Homo sapiens] Length = 283 Score = 175 bits (443), Expect = 1e-43 Identities = 102/245 (41%), Positives = 137/245 (55%), Gaps = 26/245 (10%) Query: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296 +TVCGD HGQ GDFVDRG +S+E L K +PD Sbjct: 48 VTVCGDIHGQ-----------------------GDFVDRGYYSLETFTYLLALKAKWPDR 84 Query: 297 FHLLRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGL 355 LLRGNHE+ + Q+YGF E + KY A + ++VF+ L +A I+ ++L +HGGL Sbjct: 85 ITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGL 144 Query: 356 FSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFL 415 S D TLD IR IERN++ P G CDL+WSDP+ + +IS RG FG VT F+ Sbjct: 145 -SPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFV 203 Query: 416 EENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQ 475 NNL I R+H++ EGY+ + VTV+SAPNYC + GN AS + + + R + Sbjct: 204 HINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTR-EPKL 262 Query: 476 FTAVP 480 F AVP Sbjct: 263 FRAVP 267 >gi|23312378 protein phosphatase with EF hand calcium-binding domain 1 isoform 3 [Homo sapiens] Length = 591 Score = 171 bits (432), Expect = 2e-42 Identities = 103/342 (30%), Positives = 176/342 (51%), Gaps = 37/342 (10%) Query: 156 EHKRSVVDSLD-IESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILV 214 E ++ + D D ++S+ + D Y+GP+L+ +T + + L++ +K+Q+ LH ++L Sbjct: 86 ESEQDMRDRWDYVDSIDVPDSYNGPRLQF-PLTCTDIDLLLEAFKEQQILHAHYVLEVLF 144 Query: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274 + K+VL ++ ++++T+CGD HG+ DL IF NGLPSE NPY+FNGDFVD Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204 Query: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYT---AQMYELF 331 RG S+E+++ L L+YP+ HL RGNHE MN YGF E+ KY ++ ++ Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264 Query: 332 SEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQP 391 E + WLP+ ++ ++L++HGG+ + L+ + ++ERN+ M +L + Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGI--SETTDLNLLHRVERNK-------MKSVLIPPTET 315 Query: 392 QNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSH-EVKAEGYEVAH-----GGRCVTV 445 + N + +H +K G H + VT+ Sbjct: 316 NRDHDTDSK----------------HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQVVTI 359 Query: 446 FSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPM 487 FSA NY ++ N+ +YI L S P+F Q+ +P+ Sbjct: 360 FSASNYYEEGSNRGAYIKL-CSGTTPRFFQYQVTKATCFQPL 400 >gi|23312386 serine/threonine protein phosphatase with EF-hand motifs 2 [Homo sapiens] Length = 753 Score = 164 bits (414), Expect = 2e-40 Identities = 91/211 (43%), Positives = 128/211 (60%), Gaps = 6/211 (2%) Query: 166 DIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLST 225 D ES+ + D Y+GP+L + L++ ++ +++LH + +L + K+ L +L Sbjct: 104 DYESIEVPDSYTGPRLSFPLLP-DHATALVEAFRLKQQLHARYVLNLLYETKKHLVQLPN 162 Query: 226 LVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILT 285 + + +E+ITVCGD HGQ DL+ IF NGLPS Y+FNGDFVDRG SVE+++ Sbjct: 163 INRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPERSYVFNGDFVDRGKDSVEILMI 222 Query: 286 LFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYEL---FSEVFEWLPLAQ 342 LF F L+YP FHL RGNHE +N YGF EV KY E+ +VF WLPLA Sbjct: 223 LFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKYKVHGKEILRTLQDVFCWLPLAT 282 Query: 343 CINGKVLIMHGGLFSEDGVTLDDIRKIERNR 373 I+ KVLI+HGG+ D L+ + KIER++ Sbjct: 283 LIDEKVLILHGGV--SDITDLELLDKIERSK 311 Score = 90.5 bits (223), Expect = 3e-18 Identities = 44/97 (45%), Positives = 62/97 (63%), Gaps = 2/97 (2%) Query: 383 DLLWSDPQPQNG-RSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGR 441 D+LWSDP Q G ++ + RG C FGPDVT+ L++ N+ ++IRSHE K EGYE H + Sbjct: 443 DILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRK 502 Query: 442 CVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTA 478 +T+FSA NY + N+ +Y+ L G L P Q+ A Sbjct: 503 VLTIFSASNYYEVGSNRGAYVKL-GPALTPHIVQYQA 538 >gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1 [Homo sapiens] Length = 494 Score = 89.0 bits (219), Expect = 9e-18 Identities = 42/136 (30%), Positives = 77/136 (56%), Gaps = 3/136 (2%) Query: 24 ALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALG 83 A + AE K Q N Y+ KDY A +Y++AI++ P NA YYGNR+ + + ALG Sbjct: 24 AKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALG 83 Query: 84 DATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIV 143 DA +++ LD +++G+ R +++LG AA R ++ +++ + A+ +++ N ++ Sbjct: 84 DAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNANAVM 143 Query: 144 KQKAFERAIAGDEHKR 159 + +E+ D KR Sbjct: 144 E---YEKIAETDFEKR 156 Score = 63.2 bits (152), Expect = 5e-10 Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 11/151 (7%) Query: 17 DEPPADGALKRAEELKTQAND---YFKAKDYENAIKFYSQAIELNPSN----AIYYGNRS 69 D A A + A+ LK + D FK +Y+ A + Y++A+ ++P+N A Y NR Sbjct: 242 DHEKACIACRNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRG 301 Query: 70 LAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVV---KVK 126 + A+ D T A++LD YIK Y RRA M ++ A+RDYE V K K Sbjct: 302 TVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTK 361 Query: 127 PHDKDAKMKYQECNKIVKQKAFERAIAGDEH 157 H + K E K K+K + + + D++ Sbjct: 362 EHKQLLKNAQLELRK-SKRKDYYKILGVDKN 391 >gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic subunit, alpha [Homo sapiens] Length = 384 Score = 86.7 bits (213), Expect = 5e-17 Identities = 66/245 (26%), Positives = 101/245 (41%), Gaps = 60/245 (24%) Query: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274 + KE+L++ S E +TV GD HGQ GD++D Sbjct: 183 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 215 Query: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEV 334 RG +S+E+++ L K+ Y + +L NHE+ + Q+Y E K+ + Sbjct: 216 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGD----- 270 Query: 335 FEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNG 394 G++ +HGGL S TL IR + ++ P GPM DLL+SDP Sbjct: 271 -----------GQLFCLHGGL-SPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDH-- 316 Query: 395 RSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQ 454 D + F + L + R+H++ G+ H V +FS PNYC Sbjct: 317 --------------DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYH 362 Query: 455 MGNKA 459 G A Sbjct: 363 CGGMA 367 >gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] Length = 313 Score = 85.9 bits (211), Expect = 8e-17 Identities = 44/119 (36%), Positives = 69/119 (57%) Query: 15 PRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLR 74 P PP++ AE LKT+ N+ K +++E A+ FY +AIELNP+NA+Y+ NR+ AY + Sbjct: 78 PARTPPSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSK 137 Query: 75 TECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAK 133 Y A+ D RAI +D Y K Y R + +L K A+ Y+ +++ P ++ K Sbjct: 138 LGNYAGAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNETYK 196 >gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic subunit, alpha [Homo sapiens] Length = 254 Score = 85.5 bits (210), Expect = 1e-16 Identities = 65/242 (26%), Positives = 100/242 (41%), Gaps = 60/242 (24%) Query: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274 + KE+L++ S E +TV GD HGQ GD++D Sbjct: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94 Query: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEV 334 RG +S+E+++ L K+ Y + +L NHE+ + Q+Y E K+ + Sbjct: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGD----- 149 Query: 335 FEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNG 394 G++ +HGGL S TL IR + ++ P GPM DLL+SDP Sbjct: 150 -----------GQLFCLHGGL-SPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDH-- 195 Query: 395 RSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQ 454 D + F + L + R+H++ G+ H V +FS PNYC Sbjct: 196 --------------DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYH 241 Query: 455 MG 456 G Sbjct: 242 CG 243 >gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic subunit, alpha [Homo sapiens] Length = 254 Score = 85.5 bits (210), Expect = 1e-16 Identities = 65/242 (26%), Positives = 100/242 (41%), Gaps = 60/242 (24%) Query: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274 + KE+L++ S E +TV GD HGQ GD++D Sbjct: 62 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 94 Query: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEV 334 RG +S+E+++ L K+ Y + +L NHE+ + Q+Y E K+ + Sbjct: 95 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGD----- 149 Query: 335 FEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNG 394 G++ +HGGL S TL IR + ++ P GPM DLL+SDP Sbjct: 150 -----------GQLFCLHGGL-SPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDH-- 195 Query: 395 RSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQ 454 D + F + L + R+H++ G+ H V +FS PNYC Sbjct: 196 --------------DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYH 241 Query: 455 MG 456 G Sbjct: 242 CG 243 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.136 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,463,255 Number of Sequences: 37866 Number of extensions: 870505 Number of successful extensions: 2572 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 89 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 2242 Number of HSP's gapped (non-prelim): 249 length of query: 499 length of database: 18,247,518 effective HSP length: 106 effective length of query: 393 effective length of database: 14,233,722 effective search space: 5593852746 effective search space used: 5593852746 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.