Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 5453936

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
         (500 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                     1048   0.0  
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...   451   e-127
gi|110624763 POU domain, class 3, transcription factor 4 [Homo s...   377   e-104
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s...   370   e-102
gi|42476164 POU class 2 homeobox 1 [Homo sapiens]                     206   3e-53
gi|148664218 POU transcription factor [Homo sapiens]                  202   6e-52
gi|4505959 POU domain, class 2, transcription factor 2 [Homo sap...   194   1e-49
gi|42560248 POU domain, class 5, transcription factor 1 isoform ...   190   2e-48
gi|116235491 POU domain, class 5, transcription factor 1 isoform...   189   4e-48
gi|227430410 POU class 5 homeobox 1B [Homo sapiens]                   183   3e-46
gi|170650730 pituitary specific transcription factor 1 isoform b...   181   1e-45
gi|4505955 pituitary specific transcription factor 1 isoform alp...   181   1e-45
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...   179   7e-45
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]     178   1e-44
gi|4505965 POU class 4 homeobox 3 [Homo sapiens]                      154   1e-37
gi|23463326 POU domain class 5, transcription factor 2 [Homo sap...   142   5e-34
gi|223890225 POU class 6 homeobox 1 [Homo sapiens]                    135   7e-32
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...   105   1e-22
gi|122937424 one cut homeobox 3 [Homo sapiens]                         87   3e-17
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    82   1e-15
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    82   1e-15
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    82   1e-15
gi|153792074 proline rich 12 [Homo sapiens]                            81   3e-15
gi|40288197 GATA binding protein 6 [Homo sapiens]                      80   3e-15
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    80   6e-15
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    79   1e-14
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    79   1e-14
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    79   1e-14
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    70   4e-12
gi|73476377 LBXCOR1 homolog [Homo sapiens]                             66   6e-11

>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 1048 bits (2710), Expect = 0.0
 Identities = 500/500 (100%), Positives = 500/500 (100%)

Query: 1   MATAASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTS 60
           MATAASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTS
Sbjct: 1   MATAASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTS 60

Query: 61  GAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASS 120
           GAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASS
Sbjct: 61  GAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASS 120

Query: 121 PWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPH 180
           PWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPH
Sbjct: 121 PWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPH 180

Query: 181 QGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGP 240
           QGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGP
Sbjct: 181 QGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGP 240

Query: 241 GGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGG 300
           GGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGG
Sbjct: 241 GGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGG 300

Query: 301 AGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTI 360
           AGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTI
Sbjct: 301 AGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTI 360

Query: 361 CRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGA 420
           CRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGA
Sbjct: 361 CRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGA 420

Query: 421 LESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQ 480
           LESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQ
Sbjct: 421 LESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQ 480

Query: 481 VGTVSADTPPPHHGLQTSVQ 500
           VGTVSADTPPPHHGLQTSVQ
Sbjct: 481 VGTVSADTPPPHHGLQTSVQ 500


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
           sapiens]
          Length = 443

 Score =  451 bits (1159), Expect = e-127
 Identities = 289/530 (54%), Positives = 311/530 (58%), Gaps = 117/530 (22%)

Query: 1   MATAASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTS 60
           MATAASN Y   + L ++ SIVH++  G                     GMQ G+     
Sbjct: 1   MATAASNHY---SLLTSSASIVHAEPPG---------------------GMQQGA----- 31

Query: 61  GAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEAS- 119
           G YR   S   +VQ D+  GA+ ++  GH LSHAHQW+TAL H                 
Sbjct: 32  GGYREAQS---LVQGDY--GALQSN--GHPLSHAHQWITALSHGGGGGGGGGGGGGGGGG 84

Query: 120 ------SPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRG----- 168
                 SPWS S +G      QP   P    Q    +GG G D+LH   AL  +      
Sbjct: 85  GGGGDGSPWSTSPLG------QPDIKPSVVVQ----QGGRG-DELHGPGALQQQHQQQQQ 133

Query: 169 -----------------PPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAG 211
                            PPHL       H G PG W           +AAAAAHLP   G
Sbjct: 134 QQQQQQQQQQQQQQQQRPPHLVHHAANHHPG-PGAW----------RSAAAAAHLPPSMG 182

Query: 212 GQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRG-DTPELAEH 270
                   LLYSQP  FTVNGML           GAGG    L H GL    D P  A+H
Sbjct: 183 ASNG---GLLYSQPS-FTVNGML-----------GAGGQPAGLHHHGLRDAHDEPHHADH 227

Query: 271 HHHHHHHAHPHPPHPHHAQGPPHHGGGGGGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFK 330
           H H H H H  PP P   QGPP H G           HDPHSDEDTPTSDDLEQFAKQFK
Sbjct: 228 HPHPHSHPHQQPPPPPPPQGPPGHPGA---------HHDPHSDEDTPTSDDLEQFAKQFK 278

Query: 331 QRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSS 390
           QRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSS
Sbjct: 279 QRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSS 338

Query: 391 TGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVV 450
           +GSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEIT+LADSLQLEKEVV
Sbjct: 339 SGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVV 398

Query: 451 RVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSADTPPPHHGLQTSVQ 500
           RVWFCNRRQKEKRMTPPG      +DVY      S DT PPHHG+QT VQ
Sbjct: 399 RVWFCNRRQKEKRMTPPGGTLPGAEDVYGG----SRDT-PPHHGVQTPVQ 443


>gi|110624763 POU domain, class 3, transcription factor 4 [Homo
           sapiens]
          Length = 361

 Score =  377 bits (968), Expect = e-104
 Identities = 253/494 (51%), Positives = 283/494 (57%), Gaps = 144/494 (29%)

Query: 1   MATAASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTS 60
           MATAASNPY    S+L++ S+VH+D+AG                      MQ GS     
Sbjct: 1   MATAASNPY----SILSSTSLVHADSAG----------------------MQQGSP---- 30

Query: 61  GAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASS 120
             +R      K++QSD++QG     + GH L H   WVT+L                   
Sbjct: 31  --FRNPQ---KLLQSDYLQGV---PSNGHPLGH--HWVTSLSDGG--------------- 65

Query: 121 PWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPH 180
           PWS +   +A SP       P            GR+DL  G  +HHR P H+    P  H
Sbjct: 66  PWSST---LATSPLDQQDVKP------------GREDLQLGAIIHHRSP-HVAHHSP--H 107

Query: 181 QGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLS----A 236
             HP  WGA+ A              PS+    QP     +YSQPG FTV+GML      
Sbjct: 108 TNHPNAWGASPAPN------------PSITSSGQPLN---VYSQPG-FTVSGMLEHGGLT 151

Query: 237 PPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGG 296
           PP        A   AQSL HP L                             + PP HG 
Sbjct: 152 PPP-------AAASAQSL-HPVL-----------------------------REPPDHGE 174

Query: 297 GGGGAGPGLNSH--DPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNV 354
                   L SH    HSDE+TPTSD+LEQFAKQFKQRRIKLGFTQADVGLALGTLYGNV
Sbjct: 175 --------LGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNV 226

Query: 355 FSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIE 414
           FSQTTICRFE LQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIE
Sbjct: 227 FSQTTICRFEGLQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIE 286

Query: 415 VSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTP 474
           VSVKG LE+HFLKCPKP+AQEI++LADSLQLEKEVVRVWFCNRRQKEKRMTPPG QQ  P
Sbjct: 287 VSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQ--P 344

Query: 475 DDVYSQVGTVSADT 488
            +VYS   TV  DT
Sbjct: 345 HEVYSH--TVKTDT 356


>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
           sapiens]
          Length = 451

 Score =  370 bits (951), Expect = e-102
 Identities = 251/502 (50%), Positives = 271/502 (53%), Gaps = 101/502 (20%)

Query: 39  GGGGGAGGGGGGMQPGSAAVTSGAYRGDP----SSVKMVQSDFMQGAMAASNGGHMLSHA 94
           G GGGAGG G  M P +AA  + A   +     ++ + VQ   M      +  GH +  A
Sbjct: 11  GPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQK-LMHHEWLGAGAGHPVGLA 69

Query: 95  H-QWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGA 153
           H QW   LP                   W+G                P    G    GG 
Sbjct: 70  HPQW---LPTGGGGGG-----------DWAGG---------------PHLEHGKAGGGGT 100

Query: 154 GR-DDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHL------ 206
           GR DD   G   H R            HQG       AA A AA A  + A HL      
Sbjct: 101 GRADDGGGGGGFHAR----------LVHQG-------AAHAGAAWAQGSTAHHLGPAMSP 143

Query: 207 -PSMAGGQQPPPQSLL----YSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPG--- 258
            P  +GG QP P  L     Y   GG  + GML+A      GGGGAG G    +H     
Sbjct: 144 SPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAA------GGGGAGPGLHHALHEDGHE 197

Query: 259 --LVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGGAGPGLNSHDPHSDEDT 316
             L     P L  H H H    H H    H A    H G GGGG+  G      HSDED 
Sbjct: 198 AQLEPSPPPHLGAHGHAH---GHAHAGGLHAAAAHLHPGAGGGGSSVG-----EHSDEDA 249

Query: 317 PTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKL 376
           P+SDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKL
Sbjct: 250 PSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKL 309

Query: 377 KPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEI 436
           KPLLNKWLEE DSS+GSPT++DKIAAQGRKRKKRTSIEV VKGALESHFLKCPKPSA EI
Sbjct: 310 KPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEI 369

Query: 437 TNLADSLQLEKEVVRVWFCNRRQKEKRMTP-PGIQQQTPDDVYSQ---------VGTVSA 486
           T LADSLQLEKEVVRVWFCNRRQKEKRMTP  G      DDVY+              SA
Sbjct: 370 TGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGGASPPSA 429

Query: 487 DTPPP--------HHGLQTSVQ 500
             PPP        HH L  SVQ
Sbjct: 430 PPPPPPAALHHHHHHTLPGSVQ 451



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 64/206 (31%), Positives = 72/206 (34%), Gaps = 51/206 (24%)

Query: 21  IVHSDAAGAGGGGGG------------GGGGGGGGA--GGGGGGMQPGSAAVTSGAYRGD 66
           + H      GGGGGG             GGGG G A  GGGGGG    +  V  GA    
Sbjct: 68  LAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFH--ARLVHQGAAHAG 125

Query: 67  PSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSA 126
            +  +   +  +  AM+ S G    S  HQ     P      A AA           G  
Sbjct: 126 AAWAQGSTAHHLGPAMSPSPGA---SGGHQ-----PQPLGLYAQAAYP--------GGGG 169

Query: 127 VGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGG 186
            G+AG                   GG     LH   ALH  G      P PPPH    G 
Sbjct: 170 GGLAGMLA--------------AGGGGAGPGLH--HALHEDGHEAQLEPSPPPHL---GA 210

Query: 187 WGAAAAAAAAAAAAAAAAHLPSMAGG 212
            G A   A A    AAAAHL   AGG
Sbjct: 211 HGHAHGHAHAGGLHAAAAHLHPGAGG 236



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 32/115 (27%), Positives = 44/115 (38%), Gaps = 22/115 (19%)

Query: 22  VHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGA 81
           +++ AA  GGGGGG  G    G GG G G+                     +  D  +  
Sbjct: 158 LYAQAAYPGGGGGGLAGMLAAGGGGAGPGLH------------------HALHEDGHEAQ 199

Query: 82  MAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQP 136
           +  S   H+ +H H    A  HA A    AAAA +   +   GS+VG       P
Sbjct: 200 LEPSPPPHLGAHGH----AHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAP 250



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 32/100 (32%), Positives = 36/100 (36%), Gaps = 18/100 (18%)

Query: 237 PPGPGGGGGGAG-------------GGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPP 283
           P GPGGG GG G               A   +H G    +  +L   HH        HP 
Sbjct: 9   PRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLM--HHEWLGAGAGHPV 66

Query: 284 HPHHAQGPPHHGGGGG--GAGPGLNSHDPHSDEDTPTSDD 321
              H Q  P  GGGGG    GP L  H       T  +DD
Sbjct: 67  GLAHPQWLPTGGGGGGDWAGGPHL-EHGKAGGGGTGRADD 105


>gi|42476164 POU class 2 homeobox 1 [Homo sapiens]
          Length = 743

 Score =  206 bits (525), Expect = 3e-53
 Identities = 106/166 (63%), Positives = 128/166 (77%), Gaps = 7/166 (4%)

Query: 309 DPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQL 368
           D  S E+    ++LEQFAK FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFEAL L
Sbjct: 275 DTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNL 334

Query: 369 SFKNMCKLKPLLNKWLEEA-----DSSTGSPTSIDKIAAQG--RKRKKRTSIEVSVKGAL 421
           SFKNMCKLKPLL KWL +A     DSS  SP++++    +G  R+RKKRTSIE +++ AL
Sbjct: 335 SFKNMCKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVAL 394

Query: 422 ESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPP 467
           E  FL+  KP+++EIT +AD L +EKEV+RVWFCNRRQKEKR+ PP
Sbjct: 395 EKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPP 440


>gi|148664218 POU transcription factor [Homo sapiens]
          Length = 436

 Score =  202 bits (514), Expect = 6e-52
 Identities = 126/259 (48%), Positives = 154/259 (59%), Gaps = 39/259 (15%)

Query: 246 GAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGGAGPGL 305
           G G  +Q+  HPGL  G + E        H  A  H P P H    P  GG         
Sbjct: 142 GPGLASQAFGHPGLP-GSSLE-------PHLEASQHLPVPKHL---PSSGGA-------- 182

Query: 306 NSHDPHSDEDTPTS-DDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE 364
                    D P+  ++LE+FAK FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFE
Sbjct: 183 ---------DEPSDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFE 233

Query: 365 ALQLSFKNMCKLKPLLNKWLEEADS-----STGSPTSIDKIA-AQGRKRKKRTSIEVSVK 418
           AL LSFKNMCKLKPLL KWL +A+S     S  +P+S   ++   GRKRKKRTSIE +++
Sbjct: 234 ALNLSFKNMCKLKPLLEKWLNDAESSPSDPSVSTPSSYPSLSEVFGRKRKKRTSIETNIR 293

Query: 419 GALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTP---- 474
             LE  F   PKPS++EI+ +A+ L +EKEVVRVWFCNRRQKEKR+  P      P    
Sbjct: 294 LTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPIKPPVYN 353

Query: 475 DDVYSQVGTVSADTPPPHH 493
             + S  G++   + PP H
Sbjct: 354 SRLVSPSGSLGPLSVPPVH 372


>gi|4505959 POU domain, class 2, transcription factor 2 [Homo
           sapiens]
          Length = 463

 Score =  194 bits (494), Expect = 1e-49
 Identities = 102/167 (61%), Positives = 121/167 (72%), Gaps = 10/167 (5%)

Query: 310 PHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLS 369
           P   E+    ++LEQFA+ FKQRRIKLGFTQ DVGLA+G LYGN FSQTTI RFEAL LS
Sbjct: 175 PSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLS 234

Query: 370 FKNMCKLKPLLNKWLEEA-----DSSTGSPTSIDKIA-----AQGRKRKKRTSIEVSVKG 419
           FKNMCKLKPLL KWL +A     DSS  SP  +   +       GR+RKKRTSIE +V+ 
Sbjct: 235 FKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRF 294

Query: 420 ALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTP 466
           ALE  FL   KP+++EI  +A+ L +EKEV+RVWFCNRRQKEKR+ P
Sbjct: 295 ALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINP 341


>gi|42560248 POU domain, class 5, transcription factor 1 isoform 1
           [Homo sapiens]
          Length = 360

 Score =  190 bits (483), Expect = 2e-48
 Identities = 103/193 (53%), Positives = 129/193 (66%), Gaps = 3/193 (1%)

Query: 305 LNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFE 364
           L  +   S +      +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQTTICRFE
Sbjct: 129 LEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFE 188

Query: 365 ALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESH 424
           ALQLSFKNMCKL+PLL KW+EEAD++               +++KRTSIE  V+G LE+ 
Sbjct: 189 ALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENL 248

Query: 425 FLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQV--G 482
           FL+CPKP+ Q+I+++A  L LEK+VVRVWFCNRRQK KR +    Q++  +   S    G
Sbjct: 249 FLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGG 308

Query: 483 TVSAD-TPPPHHG 494
            VS    P PH G
Sbjct: 309 PVSFPLAPGPHFG 321


>gi|116235491 POU domain, class 5, transcription factor 1 isoform 2
           [Homo sapiens]
          Length = 265

 Score =  189 bits (481), Expect = 4e-48
 Identities = 101/177 (57%), Positives = 125/177 (70%), Gaps = 3/177 (1%)

Query: 321 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 380
           +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQTTICRFEALQLSFKNMCKL+PLL
Sbjct: 50  ELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLL 109

Query: 381 NKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLA 440
            KW+EEAD++               +++KRTSIE  V+G LE+ FL+CPKP+ Q+I+++A
Sbjct: 110 QKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIA 169

Query: 441 DSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQV--GTVSAD-TPPPHHG 494
             L LEK+VVRVWFCNRRQK KR +    Q++  +   S    G VS    P PH G
Sbjct: 170 QQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFG 226


>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
          Length = 359

 Score =  183 bits (465), Expect = 3e-46
 Identities = 100/190 (52%), Positives = 125/190 (65%), Gaps = 5/190 (2%)

Query: 309 DPHSDEDTPT-SDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ 367
           +P   +D      +LEQFAK  KQ+RI LG+TQADVGL LG L+G VFSQ TICRFEALQ
Sbjct: 132 NPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFSQKTICRFEALQ 191

Query: 368 LSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLK 427
           LSFKNMCKL+PLL KW+EEAD++               +++KRTSIE  V+G LE+ FL+
Sbjct: 192 LSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENRVRGNLENLFLQ 251

Query: 428 CPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSAD 487
           CPKP+ Q I+++A  L LEK+VVRVWFCNRRQK KR +    Q++  +   S        
Sbjct: 252 CPKPTLQ-ISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVS 310

Query: 488 TPP---PHHG 494
            PP   PH G
Sbjct: 311 FPPAPGPHFG 320


>gi|170650730 pituitary specific transcription factor 1 isoform beta
           [Homo sapiens]
          Length = 317

 Score =  181 bits (459), Expect = 1e-45
 Identities = 92/152 (60%), Positives = 118/152 (77%), Gaps = 2/152 (1%)

Query: 313 DEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKN 372
           D D+P   +LE+FA +FK RRIKLG+TQ +VG AL  ++G+ FSQTTICRFE LQLSFKN
Sbjct: 149 DMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKN 208

Query: 373 MCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPS 432
            CKLK +L+KWLEEA+   G+  + +K+ A  RKRK+RT+I ++ K ALE HF +  KPS
Sbjct: 209 ACKLKAILSKWLEEAE-QVGALYN-EKVGANERKRKRRTTISIAAKDALERHFGEQNKPS 266

Query: 433 AQEITNLADSLQLEKEVVRVWFCNRRQKEKRM 464
           +QEI  +A+ L LEKEVVRVWFCNRRQ+EKR+
Sbjct: 267 SQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 298


>gi|4505955 pituitary specific transcription factor 1 isoform alpha
           [Homo sapiens]
          Length = 291

 Score =  181 bits (459), Expect = 1e-45
 Identities = 92/152 (60%), Positives = 118/152 (77%), Gaps = 2/152 (1%)

Query: 313 DEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKN 372
           D D+P   +LE+FA +FK RRIKLG+TQ +VG AL  ++G+ FSQTTICRFE LQLSFKN
Sbjct: 123 DMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKN 182

Query: 373 MCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPS 432
            CKLK +L+KWLEEA+   G+  + +K+ A  RKRK+RT+I ++ K ALE HF +  KPS
Sbjct: 183 ACKLKAILSKWLEEAE-QVGALYN-EKVGANERKRKRRTTISIAAKDALERHFGEQNKPS 240

Query: 433 AQEITNLADSLQLEKEVVRVWFCNRRQKEKRM 464
           +QEI  +A+ L LEKEVVRVWFCNRRQ+EKR+
Sbjct: 241 SQEIMRMAEELNLEKEVVRVWFCNRRQREKRV 272


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score =  179 bits (453), Expect = 7e-45
 Identities = 126/329 (38%), Positives = 156/329 (47%), Gaps = 48/329 (14%)

Query: 165 HHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQ 224
           HH     L P     H   P     A A  A AAA    AH     GG  P         
Sbjct: 104 HHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAH-DGPGGGGGPGGGGGPGGG 162

Query: 225 PGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHP-- 282
           PGG           GPGGGGGG GGG         + G +     H H   H +HP    
Sbjct: 163 PGG-------GGGGGPGGGGGGPGGG---------LLGGSAHPHPHMHSLGHLSHPAAAA 206

Query: 283 --------PHPHHAQGPPHHGGGGGGAGPGLNSHDPHS---------------DEDTPTS 319
                   PHP       HHG     A          S               D DT   
Sbjct: 207 AMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSDTDPR 266

Query: 320 DDLEQFAKQFKQRRIKLGFTQADVGLALGTL----YGNVFSQTTICRFEALQLSFKNMCK 375
           + LE FA++FKQRRIKLG TQADVG AL  L     G++ SQ+TICRFE+L LS  NM  
Sbjct: 267 E-LEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSL-SQSTICRFESLTLSHNNMIA 324

Query: 376 LKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQE 435
           LKP+L  WLEEA+ +     +  ++   G K++KRTSI    K +LE++F   P+PS+++
Sbjct: 325 LKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEK 384

Query: 436 ITNLADSLQLEKEVVRVWFCNRRQKEKRM 464
           I  +A+ L L+K VVRVWFCN+RQK+KRM
Sbjct: 385 IAAIAEKLDLKKNVVRVWFCNQRQKQKRM 413



 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 50/123 (40%), Positives = 56/123 (45%), Gaps = 3/123 (2%)

Query: 12  GNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVK 71
           G +  AAG     D  G GGG GGGGG GGG  GGGGGG   G      G   G      
Sbjct: 132 GGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHP 191

Query: 72  MVQS---DFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVG 128
            + S        A AA N    L H      A  H AAAAAAAAAA   A++  + + VG
Sbjct: 192 HMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVG 251

Query: 129 MAG 131
            AG
Sbjct: 252 AAG 254



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 44/126 (34%), Positives = 46/126 (36%), Gaps = 11/126 (8%)

Query: 88  GHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGP 147
           G +L H      AL   A  A AAA        P  G   G  G P   P        GP
Sbjct: 114 GDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGG--GP 171

Query: 148 DVKGGAGRDDLHAGTALHH---RGPPHLGPPPP------PPHQGHPGGWGAAAAAAAAAA 198
              GG     L  G+A  H       HL  P        P    HPG   AAA   AAAA
Sbjct: 172 GGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAA 231

Query: 199 AAAAAA 204
           AAAAAA
Sbjct: 232 AAAAAA 237



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 24/66 (36%), Positives = 24/66 (36%), Gaps = 25/66 (37%)

Query: 264 TPELAEHHHHHHHHAH-------PHPPHPHHA------------------QGPPHHGGGG 298
           T  LA HHHHHHHH          H   P  A                   GP   GG G
Sbjct: 95  TVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPG 154

Query: 299 GGAGPG 304
           GG GPG
Sbjct: 155 GGGGPG 160


>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
          Length = 409

 Score =  178 bits (451), Expect = 1e-44
 Identities = 136/417 (32%), Positives = 182/417 (43%), Gaps = 58/417 (13%)

Query: 90  MLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVG-MAGSPQQPPQPPPPPPQGPD 148
           M+S   +   ++PH  +       +A+ ++SP S + +   A SP            G  
Sbjct: 3   MMSLNSKQAFSMPHGGSLHVEPKYSALHSTSPGSSAPIAPSASSPSSSSNAGGGGGGGGG 62

Query: 149 VKGGAGRDDLHAGTALHHRGPPHLGPPP--PPPHQGHPGGWGAAAAAAAAAAAAAAAAHL 206
             GG GR    + +     G          P P     GG   +  A A A AA      
Sbjct: 63  GGGGGGRSSSSSSSGSSGGGGSEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVS- 121

Query: 207 PSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPE 266
            S +    PP  S         T+N +             A   +  + HP  + G    
Sbjct: 122 QSKSHHHHPPHHSPFKPDATYHTMNTIPCT--------SAASSSSVPISHPSALAGT--- 170

Query: 267 LAEHHHHHHHHAHPHPPH----------------------------------PHHA-QGP 291
              HHHHHHHH H H PH                                  PH A   P
Sbjct: 171 ---HHHHHHHHHHHHQPHQALEGELLEHLSPGLALGAMAGPDGAVVSTPAHAPHMATMNP 227

Query: 292 PHHGGGGGGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTL- 350
            H          GL SH     +      DLE FA++FKQRRIKLG TQADVG AL  L 
Sbjct: 228 MHQAALSMAHAHGLPSHMGCMSDVDADPRDLEAFAERFKQRRIKLGVTQADVGSALANLK 287

Query: 351 ---YGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKR 407
               G++ SQ+TICRFE+L LS  NM  LKP+L  WLEEA+ S     +  ++     K+
Sbjct: 288 IPGVGSL-SQSTICRFESLTLSHNNMIALKPILQAWLEEAEKSHREKLTKPELFNGAEKK 346

Query: 408 KKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRM 464
           +KRTSI    K +LE++F   P+PS+++I  +A+ L L+K VVRVWFCN+RQK+KRM
Sbjct: 347 RKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRM 403



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 29/69 (42%), Positives = 38/69 (55%), Gaps = 12/69 (17%)

Query: 11 PGNSL-LAAGSIVHSDAAGAGGGGGGGGGGGGGG--------AGGGGGGMQPGSAAVTSG 61
          PG+S  +A  +   S ++ AGGGGGGGGGGGGGG        +G  GGG   GS A+   
Sbjct: 34 PGSSAPIAPSASSPSSSSNAGGGGGGGGGGGGGGGRSSSSSSSGSSGGG---GSEAMRRA 90

Query: 62 AYRGDPSSV 70
               PS++
Sbjct: 91 CLPTPPSNI 99


>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
          Length = 338

 Score =  154 bits (390), Expect = 1e-37
 Identities = 91/199 (45%), Positives = 122/199 (61%), Gaps = 13/199 (6%)

Query: 276 HHAHPHPPHPHHAQGPPHHGGGGGGAGPGLNSHDPHSDEDTPTSD------DLEQFAKQF 329
           H   P   HPHH     H     G + P  ++  PHS      SD      +LE FA++F
Sbjct: 137 HSVMPAQIHPHHLGAMGHLHQAMGMSHP--HTVAPHSAMPACLSDVESDPRELEAFAERF 194

Query: 330 KQRRIKLGFTQADVGLALGTL----YGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLE 385
           KQRRIKLG TQADVG AL  L     G++ SQ+TICRFE+L LS  NM  LKP+L  WLE
Sbjct: 195 KQRRIKLGVTQADVGAALANLKIPGVGSL-SQSTICRFESLTLSHNNMIALKPVLQAWLE 253

Query: 386 EADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQL 445
           EA+++     S  ++     +++KRTSI    K +LE++F   P+PS+++I  +A+ L L
Sbjct: 254 EAEAAYREKNSKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDL 313

Query: 446 EKEVVRVWFCNRRQKEKRM 464
           +K VVRVWFCN+RQK+KRM
Sbjct: 314 KKNVVRVWFCNQRQKQKRM 332


>gi|23463326 POU domain class 5, transcription factor 2 [Homo
           sapiens]
          Length = 328

 Score =  142 bits (359), Expect = 5e-34
 Identities = 74/173 (42%), Positives = 107/173 (61%), Gaps = 4/173 (2%)

Query: 321 DLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLL 380
           +L+Q AK+ +Q+R+ LG++QADVG+A+G L+G V SQTTICRFEA QLS  NM KL+PLL
Sbjct: 125 ELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLL 184

Query: 381 NKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLA 440
            KWL+E ++         ++  Q   + +R S E  +  +LE  F +CPKP+ Q+I+++A
Sbjct: 185 KKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIA 244

Query: 441 DSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSADTPPPHH 493
             LQL+K+VVRVWF NR +   R T       +P ++    G      P   H
Sbjct: 245 GCLQLQKDVVRVWFYNRSKMGSRPT----NDASPREIVGTAGPPCPGAPVCFH 293


>gi|223890225 POU class 6 homeobox 1 [Homo sapiens]
          Length = 301

 Score =  135 bits (341), Expect = 7e-32
 Identities = 73/167 (43%), Positives = 100/167 (59%), Gaps = 3/167 (1%)

Query: 308 HDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQ 367
           H P  DED    +++ +FAK FK RR+ LG TQ  VG AL    G  +SQ+ ICRFE L 
Sbjct: 133 HTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLD 192

Query: 368 LSFKNMCKLKPLLNKWLEEAD--SSTGSPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESH 424
           ++ K+  KLKP+L KWL EA+  +  G    ++ +  +  +KRK+RTS       AL ++
Sbjct: 193 ITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAY 252

Query: 425 FLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQ 471
           F K P P+ QEIT +A  L  ++EVVRVWFCNRRQ  K  +   + Q
Sbjct: 253 FEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQ 299


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score =  105 bits (261), Expect = 1e-22
 Identities = 68/208 (32%), Positives = 99/208 (47%), Gaps = 40/208 (19%)

Query: 306 NSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICR--- 362
           N      + D    +++ +FAK FK RR+ LG TQ  VG AL    G  +SQ+ ICR   
Sbjct: 468 NPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTI 527

Query: 363 ---------------------------------FEALQLSFKNMCKLKPLLNKWLEEADS 389
                                            FE L ++ K+  K+KP+L +W+ EA++
Sbjct: 528 LRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEA 587

Query: 390 S--TGSPTSIDKIAAQ-GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLE 446
               G     + I ++  +KRK+RTS        L +HF K   PS QE+T +A+ L  +
Sbjct: 588 RHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYD 647

Query: 447 KEVVRVWFCNRRQKEKRMTPPGIQQQTP 474
           +EVVRVWFCN+RQ  K  T   ++Q  P
Sbjct: 648 REVVRVWFCNKRQALKN-TIKRLKQHEP 674



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 16/122 (13%)

Query: 136 PPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAA 195
           P Q    PPQ P    G G              P  L PP P     +P    AAAAAAA
Sbjct: 265 PTQQSSSPPQKPSQSPGHGL-------------PSPLTPPNPLQLVNNPLASQAAAAAAA 311

Query: 196 AAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLV 255
            ++ A++ A   +++  Q    Q +  +Q     + G +   P PG     A G     V
Sbjct: 312 MSSIASSQAFGNALSSLQGVTGQLVTNAQG---QIIGTIPLMPNPGPSSQAASGTQGLQV 368

Query: 256 HP 257
            P
Sbjct: 369 QP 370


>gi|122937424 one cut homeobox 3 [Homo sapiens]
          Length = 494

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 123/496 (24%), Positives = 180/496 (36%), Gaps = 92/496 (18%)

Query: 11  PGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSV 70
           PG   L AG     D  G GGGGG GG GG G AGGG               +RG+ +  
Sbjct: 41  PGRPGLVAGMASLLDGGGGGGGGGAGGAGGAGSAGGGAD-------------FRGELAGP 87

Query: 71  KMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAA-----AAAAVEASSPWSGS 125
                  +  AM  +     L   +  +T L H    AA A      AAA   +    G 
Sbjct: 88  -------LHPAMGMACEAPGLGGTYTTLTPLQHLPPLAAVADKFHQHAAAAAVAGAHGGH 140

Query: 126 AVGMAGSPQQPPQPPPPPPQGPDVKGG--AGRDDLHAGTALHH-RGP-----PHLGPP-P 176
                     PP PPPP      V G     RD+  A  ++ H  GP     P +G P  
Sbjct: 141 PHAHPHPAAAPPPPPPPQRLAASVSGSFTLMRDERAALASVGHLYGPYGKELPAMGSPLS 200

Query: 177 PPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQ--PP----PQSLLYSQPGGFTV 230
           P P+   P   GA            AA   P    G +  PP    P + L  +      
Sbjct: 201 PLPNALPPALHGAPQPPPPPPPPPLAAYGPPGHLAGDKLLPPAAFEPHAALLGRAEDALA 260

Query: 231 NGMLSAPPGPGGGGGGAGGGAQSLVHPGLVR--GDTPELAEHHHHHHHHAHPHPPHPHHA 288
            G+      PGGGGG   GGA S    GL+   G       H                  
Sbjct: 261 RGL------PGGGGGTGSGGAGSGSAAGLLAPLGGLAAAGAH------------------ 296

Query: 289 QGPPHHGGGGGGAGPGLNSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLG-FTQADVGLAL 347
            GP  HGGGGG  G G       + E+  T +  ++   + K+  I    F Q  +  + 
Sbjct: 297 -GP--HGGGGGPGGSGGGPSAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQ 353

Query: 348 GTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKR 407
           GTL   + +     + ++ + +F+ M        KWL+E +    S   +     + +++
Sbjct: 354 GTLSDLLRNPKPWSKLKSGRETFRRMW-------KWLQEPEFQRMSALRLAACKRKEQEQ 406

Query: 408 KKRTSIEVS---------VKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRR 458
           +K  +++            +  L + F +  +PS +    ++  L LE   V  +F N R
Sbjct: 407 QKERALQPKKQRLVFTDLQRRTLIAIFKENKRPSKEMQVTISQQLGLELNTVSNFFMNAR 466

Query: 459 QK------EKRMTPPG 468
           ++      E+  T PG
Sbjct: 467 RRCMNRWAEEPSTAPG 482



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 40/139 (28%), Positives = 48/139 (34%), Gaps = 58/139 (41%)

Query: 198 AAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSL--- 254
           A +AAA H   +A G+           PG   V GM S   G GGGGGG  GGA      
Sbjct: 28  ARSAAAQHRGLVAPGR-----------PG--LVAGMASLLDGGGGGGGGGAGGAGGAGSA 74

Query: 255 -------------VHPGL-VRGDTPEL-------------------AEHHHHH------- 274
                        +HP + +  + P L                   A+  H H       
Sbjct: 75  GGGADFRGELAGPLHPAMGMACEAPGLGGTYTTLTPLQHLPPLAAVADKFHQHAAAAAVA 134

Query: 275 -HHHAHPHPPHPHHAQGPP 292
             H  HPH  HPH A  PP
Sbjct: 135 GAHGGHPH-AHPHPAAAPP 152



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 2/41 (4%)

Query: 4   AASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGA 44
           +A+    P   L AAG+  H    G GG GG GGG   G A
Sbjct: 279 SAAGLLAPLGGLAAAGA--HGPHGGGGGPGGSGGGPSAGAA 317


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 81/269 (30%), Positives = 104/269 (38%), Gaps = 24/269 (8%)

Query: 28  GAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNG 87
           GAGGGGGGGGGGGGG  GGGGGG   G+    +GA     ++          G    S+ 
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGG-GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA 305

Query: 88  GH-MLSHAHQWVTAL---PHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPP 143
           G+ +LS   Q    +   P    AA+ + AAA  A    +G     AG  Q P    P  
Sbjct: 306 GYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA----AGGFQRFAGQNQHPSGATPTL 361

Query: 144 PQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAA 203
            Q         R   + G+   +  P     PPPPP Q  P    AAA AAA    AAA 
Sbjct: 362 NQLLTSPSPMMRS--YGGSYPEYSSP---SAPPPPPSQ--PQSQAAAAGAAAGGQQAAAG 414

Query: 204 AHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGD 263
             L    G Q         + P              PG  G   G    S + P +++  
Sbjct: 415 MGLGKDMGAQYAA------ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMK-- 466

Query: 264 TPELAEHHHHHHHHAHPHPPHPHHAQGPP 292
            P+L     + H       P+P  + GPP
Sbjct: 467 RPQLYGMGSNPHSQPQQSSPYPGGSYGPP 495



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 56/202 (27%), Positives = 69/202 (34%), Gaps = 36/202 (17%)

Query: 123 SGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPP----PPP 178
           + +++G AG     P P    PQ     GGA   D  AG      GPP L  P      P
Sbjct: 78  NNNSLGGAGGGAPQPGPDMEQPQ----HGGA--KDSAAGGQADPPGPPLLSKPGDEDDAP 131

Query: 179 PHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPP 238
           P  G P G         A         +P   GG    P+   Y            SA P
Sbjct: 132 PKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG----------SAAP 181

Query: 239 GPGGGGGGAG------GGAQS----LVHP------GLVRGDTPELAEHHHHHHHHAHPHP 282
             GG GG AG      GG QS    ++H       G      P    H  + +   + +P
Sbjct: 182 ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP 241

Query: 283 PHPHHAQGPPHHGGGGGGAGPG 304
            +     G    GGGGGG G G
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSG 263



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 15/26 (57%), Positives = 15/26 (57%), Gaps = 2/26 (7%)

Query: 265 PELAEHHHHH--HHHAHPHPPHPHHA 288
           P    HHHHH  HHH H H  H HHA
Sbjct: 22  PHQQHHHHHHAHHHHHHAHHLHHHHA 47



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 47/179 (26%), Positives = 55/179 (30%), Gaps = 38/179 (21%)

Query: 107 AAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHH 166
           A   A     +   P  G A   A   Q  P  PP   +  D      +    AG    H
Sbjct: 85  AGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEH 144

Query: 167 RGPPHLGPPPPPPHQGHPGGWGAAAA-----------AAAAAAAAAAAAHLPSMAGGQQP 215
            G   LG   PP     PGG G  AA           A A+      A       GGQQ 
Sbjct: 145 PGLGALGTQQPPV--AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202

Query: 216 PPQSLLYSQ-------PGGFTV---------NGMLSAPPG---------PGGGGGGAGG 249
           P   +++S        PG             N   +  PG          GGGGGG GG
Sbjct: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG 261



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 16/34 (47%), Positives = 17/34 (50%), Gaps = 4/34 (11%)

Query: 262 GDTPELAEHHH-HHHHHAHPHPPHPHHAQGPPHH 294
           G+ P    H   HHHHHAH H  H HH     HH
Sbjct: 15  GEAPAAPPHQQHHHHHHAHHHHHHAHHLH---HH 45



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 42/138 (30%), Positives = 49/138 (35%), Gaps = 30/138 (21%)

Query: 173 GPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNG 232
           G P P P    P   GA  +AA                GGQ  PP   L S+PG      
Sbjct: 88  GAPQPGPDMEQPQHGGAKDSAA----------------GGQADPPGPPLLSKPGDED--- 128

Query: 233 MLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDT--PELAEHHHHHHHHAHPHPPHPHHAQG 290
              APP  G   GG         HPGL    T  P +A         A P   + ++   
Sbjct: 129 --DAPPKMGEPAGGR------YEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNN-YYGSA 179

Query: 291 PPHHGGGGGGAGPGLNSH 308
            P  GG GG AGP  + H
Sbjct: 180 APASGGPGGRAGPCFDQH 197



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 39/150 (26%), Positives = 50/150 (33%), Gaps = 15/150 (10%)

Query: 110 AAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGG---------AGRDDLHA 160
           A  ++AV AS   S S+ G   +P Q P  P   P    + GG          G +   +
Sbjct: 636 ATLSSAVSASG--STSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRS 693

Query: 161 GTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAA--AAAAHLPSMA--GGQQPP 216
           G       P    PP PP  Q       A + +         A     P MA  G QQ  
Sbjct: 694 GPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTG 753

Query: 217 PQSLLYSQPGGFTVNGMLSAPPGPGGGGGG 246
           P    +  PGG    G+ S       G  G
Sbjct: 754 PSMSPHPSPGGQMHAGISSFQQSNSSGTYG 783



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 40/161 (24%), Positives = 56/161 (34%), Gaps = 17/161 (10%)

Query: 75  SDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQ 134
           S F Q   + + G  M  +  Q   + P    A +   +A+     P  G +       Q
Sbjct: 771 SSFQQSNSSGTYGPQMSQYGPQGNYSRP---PAYSGVPSASYSGPGPGMGISANNQMHGQ 827

Query: 135 QPPQPPPPPPQGPDVKGGAGRDDLHAGTA--------LHHRGPPHLGPPPPPPHQGHPGG 186
            P QP    P G     G          +        +  +G P +GPP P  ++     
Sbjct: 828 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ-- 885

Query: 187 WGAAAAAAAAAAAAAAAAHLPSMAGGQQP--PPQSLLYSQP 225
              AAAA   AAA +A +   S  G  Q      S  YSQP
Sbjct: 886 --EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP 924


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 81/269 (30%), Positives = 104/269 (38%), Gaps = 24/269 (8%)

Query: 28  GAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNG 87
           GAGGGGGGGGGGGGG  GGGGGG   G+    +GA     ++          G    S+ 
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGG-GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA 305

Query: 88  GH-MLSHAHQWVTAL---PHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPP 143
           G+ +LS   Q    +   P    AA+ + AAA  A    +G     AG  Q P    P  
Sbjct: 306 GYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA----AGGFQRFAGQNQHPSGATPTL 361

Query: 144 PQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAA 203
            Q         R   + G+   +  P     PPPPP Q  P    AAA AAA    AAA 
Sbjct: 362 NQLLTSPSPMMRS--YGGSYPEYSSP---SAPPPPPSQ--PQSQAAAAGAAAGGQQAAAG 414

Query: 204 AHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGD 263
             L    G Q         + P              PG  G   G    S + P +++  
Sbjct: 415 MGLGKDMGAQYAA------ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMK-- 466

Query: 264 TPELAEHHHHHHHHAHPHPPHPHHAQGPP 292
            P+L     + H       P+P  + GPP
Sbjct: 467 RPQLYGMGSNPHSQPQQSSPYPGGSYGPP 495



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 56/202 (27%), Positives = 69/202 (34%), Gaps = 36/202 (17%)

Query: 123 SGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPP----PPP 178
           + +++G AG     P P    PQ     GGA   D  AG      GPP L  P      P
Sbjct: 78  NNNSLGGAGGGAPQPGPDMEQPQ----HGGA--KDSAAGGQADPPGPPLLSKPGDEDDAP 131

Query: 179 PHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPP 238
           P  G P G         A         +P   GG    P+   Y            SA P
Sbjct: 132 PKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG----------SAAP 181

Query: 239 GPGGGGGGAG------GGAQS----LVHP------GLVRGDTPELAEHHHHHHHHAHPHP 282
             GG GG AG      GG QS    ++H       G      P    H  + +   + +P
Sbjct: 182 ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP 241

Query: 283 PHPHHAQGPPHHGGGGGGAGPG 304
            +     G    GGGGGG G G
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSG 263



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 15/26 (57%), Positives = 15/26 (57%), Gaps = 2/26 (7%)

Query: 265 PELAEHHHHH--HHHAHPHPPHPHHA 288
           P    HHHHH  HHH H H  H HHA
Sbjct: 22  PHQQHHHHHHAHHHHHHAHHLHHHHA 47



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 47/179 (26%), Positives = 55/179 (30%), Gaps = 38/179 (21%)

Query: 107 AAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHH 166
           A   A     +   P  G A   A   Q  P  PP   +  D      +    AG    H
Sbjct: 85  AGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEH 144

Query: 167 RGPPHLGPPPPPPHQGHPGGWGAAAA-----------AAAAAAAAAAAAHLPSMAGGQQP 215
            G   LG   PP     PGG G  AA           A A+      A       GGQQ 
Sbjct: 145 PGLGALGTQQPPV--AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202

Query: 216 PPQSLLYSQ-------PGGFTV---------NGMLSAPPG---------PGGGGGGAGG 249
           P   +++S        PG             N   +  PG          GGGGGG GG
Sbjct: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG 261



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 16/34 (47%), Positives = 17/34 (50%), Gaps = 4/34 (11%)

Query: 262 GDTPELAEHHH-HHHHHAHPHPPHPHHAQGPPHH 294
           G+ P    H   HHHHHAH H  H HH     HH
Sbjct: 15  GEAPAAPPHQQHHHHHHAHHHHHHAHHLH---HH 45



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 42/138 (30%), Positives = 49/138 (35%), Gaps = 30/138 (21%)

Query: 173 GPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNG 232
           G P P P    P   GA  +AA                GGQ  PP   L S+PG      
Sbjct: 88  GAPQPGPDMEQPQHGGAKDSAA----------------GGQADPPGPPLLSKPGDED--- 128

Query: 233 MLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDT--PELAEHHHHHHHHAHPHPPHPHHAQG 290
              APP  G   GG         HPGL    T  P +A         A P   + ++   
Sbjct: 129 --DAPPKMGEPAGGR------YEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNN-YYGSA 179

Query: 291 PPHHGGGGGGAGPGLNSH 308
            P  GG GG AGP  + H
Sbjct: 180 APASGGPGGRAGPCFDQH 197



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 39/150 (26%), Positives = 50/150 (33%), Gaps = 15/150 (10%)

Query: 110 AAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGG---------AGRDDLHA 160
           A  ++AV AS   S S+ G   +P Q P  P   P    + GG          G +   +
Sbjct: 623 ATLSSAVSASG--STSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRS 680

Query: 161 GTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAA--AAAAHLPSMA--GGQQPP 216
           G       P    PP PP  Q       A + +         A     P MA  G QQ  
Sbjct: 681 GPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTG 740

Query: 217 PQSLLYSQPGGFTVNGMLSAPPGPGGGGGG 246
           P    +  PGG    G+ S       G  G
Sbjct: 741 PSMSPHPSPGGQMHAGISSFQQSNSSGTYG 770



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 40/161 (24%), Positives = 56/161 (34%), Gaps = 17/161 (10%)

Query: 75  SDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQ 134
           S F Q   + + G  M  +  Q   + P    A +   +A+     P  G +       Q
Sbjct: 758 SSFQQSNSSGTYGPQMSQYGPQGNYSRP---PAYSGVPSASYSGPGPGMGISANNQMHGQ 814

Query: 135 QPPQPPPPPPQGPDVKGGAGRDDLHAGTA--------LHHRGPPHLGPPPPPPHQGHPGG 186
            P QP    P G     G          +        +  +G P +GPP P  ++     
Sbjct: 815 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ-- 872

Query: 187 WGAAAAAAAAAAAAAAAAHLPSMAGGQQP--PPQSLLYSQP 225
              AAAA   AAA +A +   S  G  Q      S  YSQP
Sbjct: 873 --EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP 911


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 81/269 (30%), Positives = 104/269 (38%), Gaps = 24/269 (8%)

Query: 28  GAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNG 87
           GAGGGGGGGGGGGGG  GGGGGG   G+    +GA     ++          G    S+ 
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGG-GAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSA 305

Query: 88  GH-MLSHAHQWVTAL---PHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPP 143
           G+ +LS   Q    +   P    AA+ + AAA  A    +G     AG  Q P    P  
Sbjct: 306 GYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSA----AGGFQRFAGQNQHPSGATPTL 361

Query: 144 PQGPDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAA 203
            Q         R   + G+   +  P     PPPPP Q  P    AAA AAA    AAA 
Sbjct: 362 NQLLTSPSPMMRS--YGGSYPEYSSP---SAPPPPPSQ--PQSQAAAAGAAAGGQQAAAG 414

Query: 204 AHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGD 263
             L    G Q         + P              PG  G   G    S + P +++  
Sbjct: 415 MGLGKDMGAQYAA------ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMK-- 466

Query: 264 TPELAEHHHHHHHHAHPHPPHPHHAQGPP 292
            P+L     + H       P+P  + GPP
Sbjct: 467 RPQLYGMGSNPHSQPQQSSPYPGGSYGPP 495



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 56/202 (27%), Positives = 69/202 (34%), Gaps = 36/202 (17%)

Query: 123 SGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGPP----PPP 178
           + +++G AG     P P    PQ     GGA   D  AG      GPP L  P      P
Sbjct: 78  NNNSLGGAGGGAPQPGPDMEQPQ----HGGA--KDSAAGGQADPPGPPLLSKPGDEDDAP 131

Query: 179 PHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPP 238
           P  G P G         A         +P   GG    P+   Y            SA P
Sbjct: 132 PKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYG----------SAAP 181

Query: 239 GPGGGGGGAG------GGAQS----LVHP------GLVRGDTPELAEHHHHHHHHAHPHP 282
             GG GG AG      GG QS    ++H       G      P    H  + +   + +P
Sbjct: 182 ASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYP 241

Query: 283 PHPHHAQGPPHHGGGGGGAGPG 304
            +     G    GGGGGG G G
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSG 263



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 15/26 (57%), Positives = 15/26 (57%), Gaps = 2/26 (7%)

Query: 265 PELAEHHHHH--HHHAHPHPPHPHHA 288
           P    HHHHH  HHH H H  H HHA
Sbjct: 22  PHQQHHHHHHAHHHHHHAHHLHHHHA 47



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 47/179 (26%), Positives = 55/179 (30%), Gaps = 38/179 (21%)

Query: 107 AAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHH 166
           A   A     +   P  G A   A   Q  P  PP   +  D      +    AG    H
Sbjct: 85  AGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEH 144

Query: 167 RGPPHLGPPPPPPHQGHPGGWGAAAA-----------AAAAAAAAAAAAHLPSMAGGQQP 215
            G   LG   PP     PGG G  AA           A A+      A       GGQQ 
Sbjct: 145 PGLGALGTQQPPV--AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202

Query: 216 PPQSLLYSQ-------PGGFTV---------NGMLSAPPG---------PGGGGGGAGG 249
           P   +++S        PG             N   +  PG          GGGGGG GG
Sbjct: 203 PGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGG 261



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 16/34 (47%), Positives = 17/34 (50%), Gaps = 4/34 (11%)

Query: 262 GDTPELAEHHH-HHHHHAHPHPPHPHHAQGPPHH 294
           G+ P    H   HHHHHAH H  H HH     HH
Sbjct: 15  GEAPAAPPHQQHHHHHHAHHHHHHAHHLH---HH 45



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 42/138 (30%), Positives = 49/138 (35%), Gaps = 30/138 (21%)

Query: 173 GPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNG 232
           G P P P    P   GA  +AA                GGQ  PP   L S+PG      
Sbjct: 88  GAPQPGPDMEQPQHGGAKDSAA----------------GGQADPPGPPLLSKPGDED--- 128

Query: 233 MLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDT--PELAEHHHHHHHHAHPHPPHPHHAQG 290
              APP  G   GG         HPGL    T  P +A         A P   + ++   
Sbjct: 129 --DAPPKMGEPAGGR------YEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNN-YYGSA 179

Query: 291 PPHHGGGGGGAGPGLNSH 308
            P  GG GG AGP  + H
Sbjct: 180 APASGGPGGRAGPCFDQH 197



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 39/150 (26%), Positives = 50/150 (33%), Gaps = 15/150 (10%)

Query: 110 AAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGG---------AGRDDLHA 160
           A  ++AV AS   S S+ G   +P Q P  P   P    + GG          G +   +
Sbjct: 623 ATLSSAVSASG--STSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRS 680

Query: 161 GTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAA--AAAAHLPSMA--GGQQPP 216
           G       P    PP PP  Q       A + +         A     P MA  G QQ  
Sbjct: 681 GPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTG 740

Query: 217 PQSLLYSQPGGFTVNGMLSAPPGPGGGGGG 246
           P    +  PGG    G+ S       G  G
Sbjct: 741 PSMSPHPSPGGQMHAGISSFQQSNSSGTYG 770



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 40/161 (24%), Positives = 56/161 (34%), Gaps = 17/161 (10%)

Query: 75  SDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQ 134
           S F Q   + + G  M  +  Q   + P    A +   +A+     P  G +       Q
Sbjct: 758 SSFQQSNSSGTYGPQMSQYGPQGNYSRP---PAYSGVPSASYSGPGPGMGISANNQMHGQ 814

Query: 135 QPPQPPPPPPQGPDVKGGAGRDDLHAGTA--------LHHRGPPHLGPPPPPPHQGHPGG 186
            P QP    P G     G          +        +  +G P +GPP P  ++     
Sbjct: 815 GPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ-- 872

Query: 187 WGAAAAAAAAAAAAAAAAHLPSMAGGQQP--PPQSLLYSQP 225
              AAAA   AAA +A +   S  G  Q      S  YSQP
Sbjct: 873 --EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQP 911


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 94/352 (26%), Positives = 117/352 (33%), Gaps = 64/352 (18%)

Query: 5   ASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGG--------------GGAGGGGGG 50
           A  P   G S   AG+   +    A GGGG GGGGGG              GG G   GG
Sbjct: 343 AGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGG 402

Query: 51  M----QPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAA 106
                 P S A       G P++         + + A   GG   S         P A  
Sbjct: 403 ATRPPPPRSTATPKCQSLGGPAAAYATG----KASGAGGAGGQAYSPGQPQGLLGPQAYG 458

Query: 107 AAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPP------PQGPDVKGG---AGRDD 157
                  A   + +P        +G P QPP  PPPP         PD   G     + +
Sbjct: 459 QGFGGGQAQDLSKAP------SYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGE 512

Query: 158 LHAGTALHHRGPPHLGPP------PPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAG 211
            + G A H +G P   P         P   GH GGWG ++      A+ +          
Sbjct: 513 PYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPP 572

Query: 212 GQQPPPQSLLYSQPGGFTVNGMLS----APPGPGGGGGGAGG------GAQSLVHPGLVR 261
               PP       PG +  + + S    APPG G    GAGG      G++ L  PG   
Sbjct: 573 ATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPP 632

Query: 262 GDTPELAEHHHHHHHHAHPHPPHPHHAQG----------PPHHGGGGGGAGP 303
            +  E  E    H   A P PP    A G              GG GG  GP
Sbjct: 633 AERTEDEEFLIQHLLQA-PSPPRTSGADGLVGEDGAADASKGLGGSGGAGGP 683



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 50/152 (32%), Positives = 65/152 (42%), Gaps = 30/152 (19%)

Query: 107 AAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHH 166
           A+++AAAAA E SSP   +  G A      P PPPP    P       R D    T + H
Sbjct: 249 ASSSAAAAAAEQSSPQLYNFSGAA------PGPPPPERALP-------RQD----TVIKH 291

Query: 167 RGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMA----GGQQPPPQSLLY 222
              P    PPPPP   H     A     +   +  +  H  ++A    GG +P P +   
Sbjct: 292 YQRPASAQPPPPPPPAH-----ALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEP 346

Query: 223 SQ--PGGFT--VNGMLSAPPGPGGGGGGAGGG 250
           S+  P G T   +G  + P   GGGG G GGG
Sbjct: 347 SKAGPSGATAGASGRATGPEAAGGGGAGGGGG 378



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 63/248 (25%), Positives = 92/248 (37%), Gaps = 47/248 (18%)

Query: 100 ALPHAAAAAAAAAAAAVEASSPWSGSA--VGMAGSPQQPPQPPPP-------------PP 144
           ALP ++   +++A +A +  + +      V  + S Q PP  PP              P 
Sbjct: 135 ALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPS 194

Query: 145 QGPDVKGGAGRDDLHAGTALHHRG------PPHL-GPP-PPPPHQGHPGGWGAAAAAAAA 196
           Q P V    G + L  G  L   G      PP+  GPP PPPP +  P  +   A+++AA
Sbjct: 195 QAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAA 254

Query: 197 AAAAAAAA----HLPSMAGGQQPPPQSL--------LYSQPGGFTVNGMLSAPPGPGG-- 242
           AAAA  ++    +    A G  PP ++L         Y +P     +     PP P    
Sbjct: 255 AAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRP----ASAQPPPPPPPAHAL 310

Query: 243 ------GGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGG 296
                 GG     G ++ +    + G  P            +         A GP   GG
Sbjct: 311 QHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGG 370

Query: 297 GGGGAGPG 304
           GG G G G
Sbjct: 371 GGAGGGGG 378



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 61/252 (24%), Positives = 77/252 (30%), Gaps = 49/252 (19%)

Query: 30  GGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAA----- 84
           G  G      G GG+GG GG              R    SV    +   +GA AA     
Sbjct: 663 GEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGL 722

Query: 85  ----------SNGGHMLSHAHQWVTALPHAAAAAAAAAA----------AAVEASSPWSG 124
                       GG          T++ H  A A    A             +++ P   
Sbjct: 723 GRLKEKKKGPERGGET---PEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPH 779

Query: 125 SAVGMAGSPQQPPQPPPPPPQ--------GPDVKGGAGRDDLHAGTALHHRGPPHLGPPP 176
             +  AG P  P   PPPPPQ         P     A +  +H        G P   PPP
Sbjct: 780 GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP 839

Query: 177 PPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGF--TVNGML 234
           PPP    P        A   +     AA  P +      P +SL    PG     +  + 
Sbjct: 840 PPP----PPPMPLQLEAHLRSHGLEPAAPSPRLR-----PEESL--DPPGAMQELLGALE 888

Query: 235 SAPPGPGGGGGG 246
             PP PG  G G
Sbjct: 889 PLPPAPGDTGVG 900



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 48/152 (31%), Positives = 54/152 (35%), Gaps = 21/152 (13%)

Query: 111  AAAAAVEASSPWSG-SAVGMAGSPQQP---------------PQPPPPPPQGPDVKGGAG 154
            A AAAV    P  G  +    G+P+ P               PQP PPPP  P       
Sbjct: 1425 APAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPS 1484

Query: 155  RDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQ 214
               L A T      PP   PPPPPP    P      AAA  AA     AA  PS    + 
Sbjct: 1485 PPPLVAPTPSSPPPPPL--PPPPPPAMPSPPPPPPPAAAPLAAPPEEPAA--PSPEDPEL 1540

Query: 215  PPPQSL-LYSQPGGFTVNGMLSAPPGPGGGGG 245
            P  + L L  +     V G      G  GG G
Sbjct: 1541 PDTRPLHLAKKQETAAVCGETDEEAGESGGEG 1572



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 67/252 (26%), Positives = 89/252 (35%), Gaps = 57/252 (22%)

Query: 99   TALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGP-DVKGGAGRDD 157
            + L HA + + +A+   V    P +       G+PQ PP PPPPPP  P  ++       
Sbjct: 804  SVLSHAPSPSPSASKVGVHLLEPATRD-----GAPQPPPPPPPPPPPMPLQLEAHLRSHG 858

Query: 158  LH-AGTALHHRGPPHLGPP-----------PPPPHQGHPGGWGAAAAAAAAAAAAAAAAH 205
            L  A  +   R    L PP           P PP  G  G         +     A A  
Sbjct: 859  LEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTG----VGPPNSEGKDPAGAYR 914

Query: 206  LPSMAGGQQPP---------PQSLLYSQPGGF--TVNGMLSAPPGPGGGGGGAGGGAQSL 254
             PS  G + P          P SLL  +   F  T+  M       GGG     G A   
Sbjct: 915  SPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMF------GGGAADDYGKA--- 965

Query: 255  VHPGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGGGGAG---PGLNSHDPH 311
              P    GD P+           A P P  P +    P+  G   GAG   PGL   DP+
Sbjct: 966  -GPPEDEGD-PKAG---------AGPPPGPPAYDPYGPYCPGRASGAGPETPGLGL-DPN 1013

Query: 312  SDEDTPTSDDLE 323
               + P++ + E
Sbjct: 1014 KPPELPSTVNAE 1025



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 50/191 (26%), Positives = 63/191 (32%), Gaps = 32/191 (16%)

Query: 4   AASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAY 63
           AA +  LP  S   + S  HS A    GGG G    GGGG       ++P    + S   
Sbjct: 518 AAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRP----LQSPPA 573

Query: 64  RGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWS 123
            G P  V         G+  A   G  LS        L    A + AA A   +     S
Sbjct: 574 TGRPPGV---------GSPGAP--GKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGS 622

Query: 124 GSAVGMAGSPQQPPQ------------PPPPPPQGPD-VKGGAGRDDLHAGTALHHRGPP 170
               G  G P +  +            P PP   G D + G  G  D   G      G  
Sbjct: 623 ELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLG----GSG 678

Query: 171 HLGPPPPPPHQ 181
             G PP  P++
Sbjct: 679 GAGGPPGTPYE 689



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 11/21 (52%), Positives = 13/21 (61%)

Query: 132  SPQQPPQPPPPPPQGPDVKGG 152
            +P  PP PPPPP    + KGG
Sbjct: 1038 APPPPPPPPPPPAPASEPKGG 1058



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 21/72 (29%), Positives = 23/72 (31%), Gaps = 22/72 (30%)

Query: 130  AGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAG----------------------TALHHR 167
            AG P  PP   P  P  P    GAG +    G                      +  H  
Sbjct: 978  AGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQA 1037

Query: 168  GPPHLGPPPPPP 179
             PP   PPPPPP
Sbjct: 1038 APPPPPPPPPPP 1049


>gi|40288197 GATA binding protein 6 [Homo sapiens]
          Length = 595

 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 64/195 (32%), Positives = 77/195 (39%), Gaps = 39/195 (20%)

Query: 104 AAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTA 163
           AAAAAAAAAAA+     P +     + G P               ++G       HAG A
Sbjct: 173 AAAAAAAAAAASSPVYVPTTRVGSMLPGLPYH-------------LQGSGSGPANHAGGA 219

Query: 164 LHHRGPPHLGPPPPPPHQGH-PGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLY 222
             H G P      PP   G    G GAA    A +AAA  +A  P       PP  +   
Sbjct: 220 GAHPGWPQASADSPPYGSGGGAAGGGAAGPGGAGSAAAHVSARFPY---SPSPPMANGAA 276

Query: 223 SQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAE-----------HH 271
            +PGG+   G         GG GG  GG  SL   G   G  P+ +            HH
Sbjct: 277 REPGGYAAAG--------SGGAGGVSGGGSSLAAMG---GREPQYSSLSAARPLNGTYHH 325

Query: 272 HHHHHHAHPHPPHPH 286
           HHHHHH HP P  P+
Sbjct: 326 HHHHHHHHPSPYSPY 340



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 50/191 (26%), Positives = 59/191 (30%), Gaps = 52/191 (27%)

Query: 28  GAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNG 87
           G+GGG  GGG  G GGAG         +AA  S  +   PS         M    A   G
Sbjct: 236 GSGGGAAGGGAAGPGGAG--------SAAAHVSARFPYSPSPP-------MANGAAREPG 280

Query: 88  GHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGP 147
           G+                AAA +  A  V      SG    +A    + PQ        P
Sbjct: 281 GY----------------AAAGSGGAGGV------SGGGSSLAAMGGREPQYSSLSAARP 318

Query: 148 DVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLP 207
                        GT  HH    H  P P  P+ G P       A  A          L 
Sbjct: 319 -----------LNGTYHHHHHHHHHHPSPYSPYVGAP----LTPAWPAGPFETPVLHSLQ 363

Query: 208 SMAGGQQPPPQ 218
           S AG   P P+
Sbjct: 364 SRAGAPLPVPR 374



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 1/57 (1%)

Query: 4   AASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTS 60
           +A  PY P   + A G+        A G GG GG  GGG +    GG +P  +++++
Sbjct: 260 SARFPYSPSPPM-ANGAAREPGGYAAAGSGGAGGVSGGGSSLAAMGGREPQYSSLSA 315


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 117/421 (27%), Positives = 140/421 (33%), Gaps = 134/421 (31%)

Query: 16  LAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMV-- 73
           L+A +   S AA +GG G GGGG GGG   G G G   G+ A   GA    P S  ++  
Sbjct: 329 LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGA---GAGAKGPRSYPVIPV 385

Query: 74  -QSDFMQGAMAASNG-GHMLSHAHQWVTA-----LPHAAAAAAAAAAAAVEASSPWSGSA 126
                  G +    G G +  H + +  A     L H    A AAA A   A +  +G+A
Sbjct: 386 PSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAA 445

Query: 127 --VGMAGS------------------PQQPP---------QPPPPPP--------QGPDV 149
              G++G                   P + P         QPPP PP        + P +
Sbjct: 446 PKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPAL 505

Query: 150 KGGAGRDDLHAGTAL--HHRGPPHLGPP----------PPPPHQG----------HPGGW 187
              A  D    G A       PP   PP          PPPP  G           PGG 
Sbjct: 506 LRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGS 565

Query: 188 GAAAAA-------AAAAAAAAAAAHLPSMAGGQQPPPQ--SLLYSQPGGFTVNGMLSAPP 238
           G   +A       + AAA A AAA     AG + P P    LL  +  G       SA  
Sbjct: 566 GGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFR 625

Query: 239 GPGG----------GGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHP--- 285
             GG           G  AG    +  HP            HHH HHHH H HPP P   
Sbjct: 626 PVGGKDDAESLAKLHGASAGAPHSAQTHP----------HHHHHPHHHHHHHHPPQPPSP 675

Query: 286 ---------------HHAQGP--------------PHHGG--GGGGAGPGLNSHDPHSDE 314
                          HH   P              PHH G    GG      S D   DE
Sbjct: 676 LLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDE 735

Query: 315 D 315
           D
Sbjct: 736 D 736



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/154 (31%), Positives = 62/154 (40%), Gaps = 36/154 (23%)

Query: 102 PHAAAAAAAAAAAAVEASSPWSGSAVG--MAGSPQQPPQPPPPPPQGPDVKGGAGRDDLH 159
           P ++  AAA AAAA  A     G  +G  + G+P  PP PPPPPP               
Sbjct: 255 PLSSVKAAAVAAAAAVAGG---GGLLGPHLLGAP--PPPPPPPPP--------------- 294

Query: 160 AGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQS 219
                   G PH     P           AA  AAA+ +AAAA+  + + +GG       
Sbjct: 295 ---LAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGG------- 344

Query: 220 LLYSQPGGFTVNGMLSAPPGPG-GGGGGAGGGAQ 252
              +  GG    G   A  G G G G GAG GA+
Sbjct: 345 ---AGTGGGGAGGGCVAGVGVGAGAGAGAGAGAK 375



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 2/60 (3%)

Query: 107 AAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHH 166
           A A A A  +  +S       G  G P     PPPPPP  P    G G      G+ +HH
Sbjct: 803 APAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSS--PGSPVHH 860


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 95/365 (26%), Positives = 120/365 (32%), Gaps = 94/365 (25%)

Query: 28  GAGGG----------GGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDF 77
           GAGG           G  G G G  G GGGG  +Q    ++  G+    PS   + Q D+
Sbjct: 548 GAGGSKLPPVLANLMGSMGAGKGPQGPGGGGINVQEILTSIM-GSPNSHPSEELLKQPDY 606

Query: 78  MQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAV-GMAGSPQQP 136
                       ++ H       + +            ++   P  G  + G  G P  P
Sbjct: 607 SDKIKQM-----LVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGP 661

Query: 137 PQP----PPPPPQGPD---------VKGGAGRDDLHAGTALHHRGPPHLG-----PPPPP 178
             P    PPPPP+G D         ++GG  R     G   +HRG    G     PPPPP
Sbjct: 662 VGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPP 721

Query: 179 -------------------------------PHQGHPGGWGAAAAAAA--AAAAAAAAAH 205
                                          PH+G  GG G ++             + H
Sbjct: 722 FRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGH 781

Query: 206 LP------SMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGL 259
            P      SM GG    P    +  PGG    G    P    GGG GAGGG +    PG 
Sbjct: 782 RPHEGPGGSMGGGGGHRP----HEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGG 837

Query: 260 VRGDTPELAEHH---------HHHH----HHAHPH---PPHPHHAQGPPHHGGGGGGAGP 303
             G +     H          H  H    H  H H   PPH H     P HGGGG     
Sbjct: 838 SMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHD 897

Query: 304 GLNSH 308
           G +SH
Sbjct: 898 GGHSH 902



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 67/248 (27%), Positives = 76/248 (30%), Gaps = 57/248 (22%)

Query: 31  GGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHM 90
           GG G G G    G GG GG   P       GA RG  S           G      GGH 
Sbjct: 694 GGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGA-RGGRSGGGPPNGRGGPGGGMVGGGGHR 752

Query: 91  LSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVK 150
                      PH         ++      P  G   GM GS  +P + P     G  + 
Sbjct: 753 -----------PHEGPGGGMGNSSG---HRPHEGPGGGM-GSGHRPHEGP-----GGSMG 792

Query: 151 GGAGRDDLHAGTALHHRGPPHLGP-------PPPPPHQGHPGGWGAAAA----AAAAAAA 199
           GG G           HR  PH GP           PH+G  GG GA            + 
Sbjct: 793 GGGG-----------HR--PHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSM 839

Query: 200 AAAAAHLPSMAGGQQPPPQSLLYSQPG--GFTVNGMLSAPP-------GPGGGGGGAGGG 250
             +  H P    G   P     +  PG  G    G    PP       GPG GGGG  G 
Sbjct: 840 GGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRG---PPPHEHRGHDGPGHGGGGHRGH 896

Query: 251 AQSLVHPG 258
                H G
Sbjct: 897 DGGHSHGG 904



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 54/200 (27%), Positives = 61/200 (30%), Gaps = 65/200 (32%)

Query: 11  PGNSLLAAGSIVHSDAAGAGGG-------------GGGGGGG-----GGGGAGGGGGGMQ 52
           PG  ++  G   H    G GGG             GGG G G     G GG+ GGGGG +
Sbjct: 741 PGGGMVGGGG--HRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHR 798

Query: 53  PGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAA 112
           P                          G   +   GH            PH        A
Sbjct: 799 PHEG----------------------PGGGISGGSGHR-----------PHEGPGGGMGA 825

Query: 113 AAAVEASSPWSGSAVGMAG-SPQQPPQPPPPPPQGP-DVKGGAGRDDLHAGTALH----H 166
                      GS  G  G  P + P    P    P DV G  G D  H G   H    H
Sbjct: 826 GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHD--HRGPPPHEHRGH 883

Query: 167 RGPPHLGPPPPPPHQGHPGG 186
            GP H G      H+GH GG
Sbjct: 884 DGPGHGG----GGHRGHDGG 899


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 117/421 (27%), Positives = 140/421 (33%), Gaps = 134/421 (31%)

Query: 16  LAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMV-- 73
           L+A +   S AA +GG G GGGG GGG   G G G   G+ A   GA    P S  ++  
Sbjct: 329 LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGA---GAGAKGPRSYPVIPV 385

Query: 74  -QSDFMQGAMAASNG-GHMLSHAHQWVTA-----LPHAAAAAAAAAAAAVEASSPWSGSA 126
                  G +    G G +  H + +  A     L H    A AAA A   A +  +G+A
Sbjct: 386 PSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAA 445

Query: 127 --VGMAGS------------------PQQPP---------QPPPPPP--------QGPDV 149
              G++G                   P + P         QPPP PP        + P +
Sbjct: 446 PKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPAL 505

Query: 150 KGGAGRDDLHAGTAL--HHRGPPHLGPP----------PPPPHQG----------HPGGW 187
              A  D    G A       PP   PP          PPPP  G           PGG 
Sbjct: 506 LRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGS 565

Query: 188 GAAAAA-------AAAAAAAAAAAHLPSMAGGQQPPPQ--SLLYSQPGGFTVNGMLSAPP 238
           G   +A       + AAA A AAA     AG + P P    LL  +  G       SA  
Sbjct: 566 GGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFR 625

Query: 239 GPGG----------GGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHP--- 285
             GG           G  AG    +  HP            HHH HHHH H HPP P   
Sbjct: 626 PVGGKDDAESLAKLHGASAGAPHSAQTHP----------HHHHHPHHHHHHHHPPQPPSP 675

Query: 286 ---------------HHAQGP--------------PHHGG--GGGGAGPGLNSHDPHSDE 314
                          HH   P              PHH G    GG      S D   DE
Sbjct: 676 LLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCCYPSEDSSEDE 735

Query: 315 D 315
           D
Sbjct: 736 D 736



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/154 (31%), Positives = 62/154 (40%), Gaps = 36/154 (23%)

Query: 102 PHAAAAAAAAAAAAVEASSPWSGSAVG--MAGSPQQPPQPPPPPPQGPDVKGGAGRDDLH 159
           P ++  AAA AAAA  A     G  +G  + G+P  PP PPPPPP               
Sbjct: 255 PLSSVKAAAVAAAAAVAGG---GGLLGPHLLGAP--PPPPPPPPP--------------- 294

Query: 160 AGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQS 219
                   G PH     P           AA  AAA+ +AAAA+  + + +GG       
Sbjct: 295 ---LAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGG------- 344

Query: 220 LLYSQPGGFTVNGMLSAPPGPG-GGGGGAGGGAQ 252
              +  GG    G   A  G G G G GAG GA+
Sbjct: 345 ---AGTGGGGAGGGCVAGVGVGAGAGAGAGAGAK 375



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 2/60 (3%)

Query: 107 AAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHH 166
           A A A A  +  +S       G  G P     PPPPPP  P    G G      G+ +HH
Sbjct: 803 APAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSS--PGSPVHH 860


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 117/421 (27%), Positives = 140/421 (33%), Gaps = 134/421 (31%)

Query: 16  LAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMV-- 73
           L+A +   S AA +GG G GGGG GGG   G G G   G+ A   GA    P S  ++  
Sbjct: 329 LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGA---GAGAKGPRSYPVIPV 385

Query: 74  -QSDFMQGAMAASNG-GHMLSHAHQWVTA-----LPHAAAAAAAAAAAAVEASSPWSGSA 126
                  G +    G G +  H + +  A     L H    A AAA A   A +  +G+A
Sbjct: 386 PSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAA 445

Query: 127 --VGMAGS------------------PQQPP---------QPPPPPP--------QGPDV 149
              G++G                   P + P         QPPP PP        + P +
Sbjct: 446 PKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPAL 505

Query: 150 KGGAGRDDLHAGTAL--HHRGPPHLGPP----------PPPPHQG----------HPGGW 187
              A  D    G A       PP   PP          PPPP  G           PGG 
Sbjct: 506 LRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGS 565

Query: 188 GAAAAA-------AAAAAAAAAAAHLPSMAGGQQPPPQ--SLLYSQPGGFTVNGMLSAPP 238
           G   +A       + AAA A AAA     AG + P P    LL  +  G       SA  
Sbjct: 566 GGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFR 625

Query: 239 GPGG----------GGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHP--- 285
             GG           G  AG    +  HP            HHH HHHH H HPP P   
Sbjct: 626 PVGGKDDAESLAKLHGASAGAPHSAQTHP----------HHHHHPHHHHHHHHPPQPPSP 675

Query: 286 ---------------HHAQGP--------------PHHGG--GGGGAGPGLNSHDPHSDE 314
                          HH   P              PHH G    GG      S D   DE
Sbjct: 676 LLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCCYPSEDSSEDE 735

Query: 315 D 315
           D
Sbjct: 736 D 736



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/154 (31%), Positives = 62/154 (40%), Gaps = 36/154 (23%)

Query: 102 PHAAAAAAAAAAAAVEASSPWSGSAVG--MAGSPQQPPQPPPPPPQGPDVKGGAGRDDLH 159
           P ++  AAA AAAA  A     G  +G  + G+P  PP PPPPPP               
Sbjct: 255 PLSSVKAAAVAAAAAVAGG---GGLLGPHLLGAP--PPPPPPPPP--------------- 294

Query: 160 AGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQS 219
                   G PH     P           AA  AAA+ +AAAA+  + + +GG       
Sbjct: 295 ---LAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGG------- 344

Query: 220 LLYSQPGGFTVNGMLSAPPGPG-GGGGGAGGGAQ 252
              +  GG    G   A  G G G G GAG GA+
Sbjct: 345 ---AGTGGGGAGGGCVAGVGVGAGAGAGAGAGAK 375



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 2/60 (3%)

Query: 107 AAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHH 166
           A A A A  +  +S       G  G P     PPPPPP  P    G G      G+ +HH
Sbjct: 803 APAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSS--PGSPVHH 860


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 76/282 (26%), Positives = 90/282 (31%), Gaps = 41/282 (14%)

Query: 33  GGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHMLS 92
           GGGGGG    G GGG GG+           +R  P  + + Q+    G     +G     
Sbjct: 10  GGGGGGFHRRGGGGGRGGLHD---------FRSPPPGMGLNQNRGPMGPGPGQSGPKPPI 60

Query: 93  HAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPP-----PPPPQGP 147
                    PH             +   P            QQPP PP     P   QGP
Sbjct: 61  PPPP-----PHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP 115

Query: 148 DVKGGAGRDDLHAGTALHHRGPPHLGPP---PPPPHQGHPGGWGAAAAAAAAAAAAAAAA 204
               G G     + +A     P    PP   P P     P    A   A      ++   
Sbjct: 116 GPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVP 175

Query: 205 HLPSMAGGQQPPPQSLLYSQPG-------GFTVNGMLSAPPGPGGGGG-GAGGGAQSLVH 256
             P  AGG  PPP ++    PG       G    G +   P PGGG G    GG     H
Sbjct: 176 TTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPH 235

Query: 257 PGLVRGDTPELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGGG 298
            G   G  P     HH         P H  H QGPP  G GG
Sbjct: 236 RG---GGEPRGGRQHH--------PPYHQQHHQGPPPGGPGG 266


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 82/315 (26%), Positives = 108/315 (34%), Gaps = 59/315 (18%)

Query: 15  LLAAGSIVHSDAAGAGGGGGGGGGGGGG----------GAGGGGGGM----QPGSAAVTS 60
           +L AG        G+GGGG G GGG GG          GAG GGG M    QP  AA  +
Sbjct: 369 VLGAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGAGPGGGAMFWGHQPSGAAKDA 428

Query: 61  GAYRGDPSSVKMVQS--DFMQGAMAASNGGHMLSHAHQWVTALPHAAAAAAAAAAAAVEA 118
            A     ++  +  +   F   A +     +  + +     A   AAAAAAAAAAA   A
Sbjct: 429 AAVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKAVAAAVAAAAAAAAAAAGSGA 488

Query: 119 SSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHLGP-PPP 177
             P  G+            + P    +GP        D+     AL    PP L P PPP
Sbjct: 489 PEPLDGAEPAKESGLGAEERCPSALSRGP-------LDEDGTDEAL----PPPLAPLPPP 537

Query: 178 PPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAP 237
           PP     G + +A         + A  +  +       P +                   
Sbjct: 538 PPPPARKGSYVSAFRPVVKDTESIAKLYGSAREAYGAGPARG------------------ 579

Query: 238 PGPGGGGGG--------AGGGAQSLVHPGLVRGDTPEL-AEHHHHHHHHAHPHPPHPHHA 288
           PGPG G GG         G  + +   P +   D PE+  E +             P   
Sbjct: 580 PGPGAGSGGYVSPDFLSEGSSSYNSASPDVDTADEPEVDVESNRFPDDEDAQEETEP--- 636

Query: 289 QGPPHHGGGGGGAGP 303
              P  GGG  G  P
Sbjct: 637 -SAPSAGGGPDGEQP 650



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 49/179 (27%), Positives = 61/179 (34%), Gaps = 44/179 (24%)

Query: 113 AAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHHRGPPHL 172
           +A  E S  W        G  +   +  P PP    ++   G D+          GPP  
Sbjct: 246 SATDELSHAWEDVKAMFNGGTRCGAEMAPGPPPHKSLR--CGEDEA--------AGPP-- 293

Query: 173 GPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAH------LPSMAGG---QQPPPQSLLYS 223
           GPPPP P +G     GA+  A        A         +PS   G   + PPP   L+ 
Sbjct: 294 GPPPPHPQRGLGLATGASGPAGPGGPGGGAGVRSYPVIPVPSKGFGLLQKLPPP---LFP 350

Query: 224 QPGGFTVN--------------GMLSAPPGPGGGG------GGAGGGAQSLVHPGLVRG 262
            P GF                 G     PG G GG      GGAGG   S + PG   G
Sbjct: 351 HPYGFPTAFGLCPKKDDPVLGAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGAG 409



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 45/154 (29%), Positives = 56/154 (36%), Gaps = 34/154 (22%)

Query: 175 PPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGML 234
           P PPPH+    G   AA                   G   PPP    + Q G     G  
Sbjct: 274 PGPPPHKSLRCGEDEAA-------------------GPPGPPPP---HPQRGLGLATGA- 310

Query: 235 SAPPGPGGGGGGAGGGAQSLVHP-----GLVRGDTPELAEHHHHH--HHHAHPHPPHP-- 285
           S P GPGG GGGAG  +  ++       GL++   P L  H +         P    P  
Sbjct: 311 SGPAGPGGPGGGAGVRSYPVIPVPSKGFGLLQKLPPPLFPHPYGFPTAFGLCPKKDDPVL 370

Query: 286 --HHAQGPPHHGGGGGGAGPGLNSHDPHSDEDTP 317
                +G P  G GGGGAG G  +  P +    P
Sbjct: 371 GAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPP 404



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 56/213 (26%), Positives = 70/213 (32%), Gaps = 38/213 (17%)

Query: 31  GGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNGGHM 90
           G G   G  G  G GG GGG    S  V     +G     K+                 +
Sbjct: 303 GLGLATGASGPAGPGGPGGGAGVRSYPVIPVPSKGFGLLQKLPPP--------------L 348

Query: 91  LSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQP-----PPPPPQ 145
             H + + TA             A      P +GS  G AG+      P     PP    
Sbjct: 349 FPHPYGFPTAFGLCPKKDDPVLGAGEPKGGPGTGSGGGGAGTGGGAGGPGASHLPPGAGA 408

Query: 146 GP--------DVKGGAGRD-----DLHAGTALHHRGP---PHLGPPPPPPH---QGHPGG 186
           GP            GA +D        A   ++   P   P  G  P P +   Q     
Sbjct: 409 GPGGGAMFWGHQPSGAAKDAAAVAAAAAAATVYPTFPMFWPAAGSLPVPSYPAAQSQAKA 468

Query: 187 WGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQS 219
             AA AAAAAAAAAAA +  P    G +P  +S
Sbjct: 469 VAAAVAAAAAAAAAAAGSGAPEPLDGAEPAKES 501


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,690,325
Number of Sequences: 37866
Number of extensions: 2202959
Number of successful extensions: 73314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1304
Number of HSP's successfully gapped in prelim test: 1329
Number of HSP's that attempted gapping in prelim test: 20237
Number of HSP's gapped (non-prelim): 25146
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press