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Search of human proteins with 5453832
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
(999 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 1955 0.0
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 1955 0.0
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 314 2e-85
gi|42544159 heat shock 105kD [Homo sapiens] 314 2e-85
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 304 2e-82
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 229 7e-60
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 227 5e-59
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 222 2e-57
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 222 2e-57
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 222 2e-57
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 219 8e-57
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 215 2e-55
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 207 5e-53
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 168 3e-41
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 154 5e-37
gi|48928056 heat shock protein 70kDa family member 13 precursor ... 137 5e-32
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 8e-09
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 54 6e-07
gi|70980549 programmed cell death 11 [Homo sapiens] 53 2e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 51 5e-06
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 51 5e-06
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 50 1e-05
gi|225543215 antigen identified by monoclonal antibody Ki-67 iso... 48 5e-05
gi|103472005 antigen identified by monoclonal antibody Ki-67 iso... 48 5e-05
gi|24308394 hypothetical protein LOC140893 [Homo sapiens] 47 7e-05
gi|20270186 high mobility group nucleosomal binding domain 3 iso... 47 9e-05
gi|33286446 opioid growth factor receptor [Homo sapiens] 47 1e-04
gi|58082089 hypothetical protein LOC161394 [Homo sapiens] 47 1e-04
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 46 2e-04
gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b ... 46 2e-04
>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 1955 bits (5065), Expect = 0.0
Identities = 999/999 (100%), Positives = 999/999 (100%)
Query: 1 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL 60
MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
Sbjct: 1 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL 60
Query: 61 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF 120
NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
Sbjct: 61 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF 120
Query: 121 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF 180
PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
Sbjct: 121 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF 180
Query: 181 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC 240
NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
Sbjct: 181 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC 240
Query: 241 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR 300
TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
Sbjct: 241 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR 300
Query: 301 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP 360
ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
Sbjct: 301 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP 360
Query: 361 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV 420
GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
Sbjct: 361 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV 420
Query: 421 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK 480
YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
Sbjct: 421 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK 480
Query: 481 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK 540
VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
Sbjct: 481 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK 540
Query: 541 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT 600
AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
Sbjct: 541 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT 600
Query: 601 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK 660
VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
Sbjct: 601 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK 660
Query: 661 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV 720
SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
Sbjct: 661 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV 720
Query: 721 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST 780
QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
Sbjct: 721 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST 780
Query: 781 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR 840
WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
Sbjct: 781 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR 840
Query: 841 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR 900
LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
Sbjct: 841 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR 900
Query: 901 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV 960
EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
Sbjct: 901 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV 960
Query: 961 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL 999
ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
Sbjct: 961 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL 999
>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 1955 bits (5065), Expect = 0.0
Identities = 999/999 (100%), Positives = 999/999 (100%)
Query: 1 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL 60
MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL
Sbjct: 1 MADKVRRQRPRRRVCWALVAVLLADLLALSDTLAVMSVDLGSESMKVAIVKPGVPMEIVL 60
Query: 61 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF 120
NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF
Sbjct: 61 NKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARF 120
Query: 121 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF 180
PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF
Sbjct: 121 PEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFF 180
Query: 181 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC 240
NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC
Sbjct: 181 NQAERRAVLQAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVC 240
Query: 241 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR 300
TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR
Sbjct: 241 TIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVR 300
Query: 301 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP 360
ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP
Sbjct: 301 ENPRAMAKLLREANRLKTVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVP 360
Query: 361 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV 420
GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV
Sbjct: 361 GPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAV 420
Query: 421 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK 480
YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK
Sbjct: 421 YQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRK 480
Query: 481 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK 540
VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK
Sbjct: 481 VITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIK 540
Query: 541 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT 600
AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT
Sbjct: 541 AHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDT 600
Query: 601 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK 660
VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK
Sbjct: 601 VQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDK 660
Query: 661 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV 720
SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV
Sbjct: 661 SEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSV 720
Query: 721 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST 780
QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST
Sbjct: 721 QKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAST 780
Query: 781 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR 840
WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR
Sbjct: 781 WLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGAR 840
Query: 841 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR 900
LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR
Sbjct: 841 LIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDR 900
Query: 901 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV 960
EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV
Sbjct: 901 EVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPISEPEKV 960
Query: 961 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL 999
ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL
Sbjct: 961 ETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKNDEL 999
>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
Length = 840
Score = 314 bits (805), Expect = 2e-85
Identities = 257/939 (27%), Positives = 425/939 (45%), Gaps = 116/939 (12%)
Query: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
++V+ +DLG +S VA+ + G +E + N+ S R TP ++ R G +A S I N
Sbjct: 1 MSVVGIDLGFQSCYVAVARAG-GIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISN 59
Query: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQ-ISSQLQFSPEEVLG 151
K T++ F+ G+ +P V ++ + + + + F+ E+V
Sbjct: 60 AKNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTA 119
Query: 152 MVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATAL 211
M+L+ + AE ++P+ D V++VP F+ AERR+V+ A ++AGL L+L+N+ TA AL
Sbjct: 120 MLLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVAL 179
Query: 212 SYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269
+YG++++ + +N++F DMG + ++ + K L++ FD T
Sbjct: 180 AYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGK---------LKVLATAFDTT 230
Query: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANA-DHMA 328
LGG + + E L F E+ + D++ RA+ +L +E +LK ++SANA D
Sbjct: 231 LGGRKFD----EVLVNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPL 286
Query: 329 QIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATR 388
IE M+DVD + R +F E+C DL RV P++ L+ ++ ++I V +VGGATR
Sbjct: 287 SIECFMNDVDVSGTMNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATR 346
Query: 389 VPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVE 448
+P V+E + K GK EL +NADEA G Q A LS AFKV+ F + D V YPI +
Sbjct: 347 IPAVKEKISKFFGK-ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLR 405
Query: 449 FTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYG---DLGFLGP 505
+ EE + +FS+ P KV+TF R F Y DL + P
Sbjct: 406 WNSPAEE-------GSSDCEVFSKNHAAPFSKVLTFYR-KEPFTLEAYYSSPQDLPYPDP 457
Query: 506 EDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVE 565
+ F Q +T D S +K ++ G+ S+ +LVE
Sbjct: 458 A-IAQFSVQKVT------------PQSDGSSSKVKVKVRVNVHGIFSVSSA-----SLVE 499
Query: 566 DSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEE 625
EE+ EE + +K+E QV ++
Sbjct: 500 VHKSEEN------------------------------EEPMETDQNAKEEEKMQV---DQ 526
Query: 626 AEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEK 685
E VE+ Q P E K E E + S+A +K +
Sbjct: 527 EEPHVEEQQQQTPAENK----------AESEEMETSQAGSKDKKMD-------------- 562
Query: 686 KQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSL 743
Q P K+ V+ V+L + + L + + L ++ + ++D ++ER A N++
Sbjct: 563 -QPPQAKKAKVKTSTVDLPIENQLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAV 621
Query: 744 EAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRK 803
E +++E +DKL EY++ +E+ R + KL WL ++G + +KLAEL+
Sbjct: 622 EEYVYEMRDKL-SGEYEKFVSEDDRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKN 680
Query: 804 LCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINE 863
L Q + R +E ++ P+ L + + + + +MT +EK NE
Sbjct: 681 LGQPIKIRFQESEERPKLFEELGKQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNE 740
Query: 864 TWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNG 923
W N L Q K T PV+ SK+IEAK+ L +++K K P+ + KN
Sbjct: 741 AMEWMNNKLNLQNKQSLTMDPVVKSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNA 800
Query: 924 TRAEPPLNASASDQGEKVIPPAGQ--TEDAEPISEPEKV 960
+ N QG+ P A + T+ A P +K+
Sbjct: 801 EQ-----NGPVDGQGDNPGPQAAEQGTDTAVPSDSDKKL 834
>gi|42544159 heat shock 105kD [Homo sapiens]
Length = 858
Score = 314 bits (805), Expect = 2e-85
Identities = 256/934 (27%), Positives = 437/934 (46%), Gaps = 132/934 (14%)
Query: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
++V+ +D+GS+S +A+ + G +E + N+ S R TP +++ R G +A + I +
Sbjct: 1 MSVVGLDVGSQSCYIAVARAG-GIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITH 59
Query: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFD--PQRQ-----TVHFQISSQLQFS 145
T+ F+ G+ ++P + + + L++D P + V + L FS
Sbjct: 60 ANNTVSNFKRFHGRAFNDPFI-----QKEKENLSYDLVPLKNGGVGIKVMYMGEEHL-FS 113
Query: 146 PEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLIND 205
E++ M+L + AE+ ++P+ D VI+VP FF AERR+VL AA++ GL L+L+ND
Sbjct: 114 VEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMND 173
Query: 206 NTATALSYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRG 263
TA AL+YG++++ ++ + ++F DMG + + + K L++ G
Sbjct: 174 MTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGK---------LKVLG 224
Query: 264 VGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSAN 323
FD LGG + +L E F + K D + RA+ +L +E +LK ++S+N
Sbjct: 225 TAFDPFLGGKNFDEKLVEHFCAEFKTKYK----LDAKSKIRALLRLYQECEKLKKLMSSN 280
Query: 324 A-DHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVIL 382
+ D IE M+D D K+ R +FEELCA+L +++ P+ L+ + ++++ V +
Sbjct: 281 STDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEI 340
Query: 383 VGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVV 442
VGGATR+P V+E + K GK ++ +NADEA A G Q A LS AFKV+ F V DAV
Sbjct: 341 VGGATRIPAVKERIAKFFGK-DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVP 399
Query: 443 YPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGD-LG 501
+PI + + + E+ G+H +FSR P KV+TF R F Y D G
Sbjct: 400 FPISLIWNHDSEDTEGVHE-------VFSRNHAAPFSKVLTFLRRG-PFELEAFYSDPQG 451
Query: 502 FLGPE-DLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVF 560
PE + F QN++ K D E +K ++ G+ ++
Sbjct: 452 VPYPEAKIGRFVVQNVSAQK------------DGEKSRVKVKVRVNTHGIFTISTA---- 495
Query: 561 ETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQV 620
++VE EE+ ++ + PD +N VQ++ E G Q
Sbjct: 496 -SMVEKVPTEENEMSSEADMECLNQRPPENPDTDKN----VQQD--------NSEAGTQP 542
Query: 621 ELKEEAEAPVEDGSQPPPPE--PKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVA 678
+++ +A+ + PP PE + + P+ +KA EK+ EA+KP
Sbjct: 543 QVQTDAQ---QTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPK----------- 588
Query: 679 PAPEGEKKQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQER 736
++ + VEL + + L +D L ++ + ++D ++ER
Sbjct: 589 -----------------IKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIMQDKLEKER 631
Query: 737 EKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKE 796
A N++E +++E +DKL P Y++ E+ + L+ WL +EG +
Sbjct: 632 NDAKNAVEEYVYEFRDKLCGP-YEKFICEQDHQNFLRLLTETEDWLYEEGEDQAKQAYVD 690
Query: 797 KLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTT 856
KL EL K+ + R +E ++ P+ L L H + R E E EM
Sbjct: 691 KLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKK 750
Query: 857 LEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRP 916
+EK +NE W N + QAK + PV+ +++I+ K+ L+ + ++ T+P+P
Sbjct: 751 VEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVV-----TQPKP 805
Query: 917 R---PK------------------DKNGTRAEPP 929
+ PK DKN AEPP
Sbjct: 806 KIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPP 839
>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
Length = 839
Score = 304 bits (779), Expect = 2e-82
Identities = 238/911 (26%), Positives = 422/911 (46%), Gaps = 100/911 (10%)
Query: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
++V+ +DLG + +A+ + G +E + N+ S R TP ++L R G++A S + N
Sbjct: 1 MSVVGIDLGFLNCYIAVARSG-GIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTN 59
Query: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQT---VHFQISSQLQFSPEEV 149
+ T+ F+ L G+ D+P V + R P +EL P V + + + F+ E+V
Sbjct: 60 VRNTIHGFKKLHGRSFDDPIVQTERIRLP-YELQKMPNGSAGVKVRY-LEEERPFAIEQV 117
Query: 150 LGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTAT 209
GM+L + +E+ ++P+ D VI++P FF AERR+V+ AA++AGL L+L+N+ TA
Sbjct: 118 TGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAV 177
Query: 210 ALSYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFD 267
AL+YG++++ ++ +N++F DMG + + + K L++ FD
Sbjct: 178 ALAYGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGK---------LKVLATTFD 228
Query: 268 RTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANA-DH 326
LGG + E L F ++ K + +V+EN RA+ +L +E +LK ++SANA D
Sbjct: 229 PYLGGRNFD----EALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDL 284
Query: 327 MAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGA 386
IE M+D+D +K+ R +FE+LCA L RV P++ ++ A + ++I + +VGGA
Sbjct: 285 PLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGA 344
Query: 387 TRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPIL 446
TR+P V+E + K K ++ +NADEA A G Q A LS AFKV+ F + D V Y I
Sbjct: 345 TRIPAVKEQITKFFLK-DISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSIT 403
Query: 447 VEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPE 506
+ + E+ G + +F + P P KVITF++ F Y +L +
Sbjct: 404 LRWKTSFEDGSG-------ECEVFCKNHPAPFSKVITFHK-KEPFELEAFYTNLHEVPYP 455
Query: 507 DLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVED 566
D R+ GS + V + GDS K +K ++ G+ S+ + + +E
Sbjct: 456 DARI-GSFTIQNVFPQSDGDSSK---------VKVKVRVNIHGIFSVASASVIEKQNLEG 505
Query: 567 SAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEA 626
+ ++P E E + ++
Sbjct: 506 ------------------------------------DHSDAPMETETSFKNENKDNMDKM 529
Query: 627 EAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKK 686
+ E+G Q + + TPE E G + + + + +
Sbjct: 530 QVDQEEGHQ----KCHAEHTPE------------------EEIDHTGAKTKSAVSDKQDR 567
Query: 687 QKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAF 746
K+ V+ I + + L +D L ++ + ++D ++ER A N++E +
Sbjct: 568 LNQTLKKGKVKSIDLPIQSSLCRQLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEY 627
Query: 747 IFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQ 806
+++ +D+L Y++ T E ++S L WL ++G + +KL EL+K Q
Sbjct: 628 VYDFRDRL-GTVYEKFITPEDLSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQ 686
Query: 807 GLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWA 866
+ + E ++ P+ L+ L + ++ R E EM +EK I++ +
Sbjct: 687 PIQMKYMEHEERPKALNDLGKKIQLVMKVIEAYRNKDERYDHLDPTEMEKVEKCISDAMS 746
Query: 867 WKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRA 926
W N+ + Q KL T+ PV+ +I AK LD ++ K K P K K +
Sbjct: 747 WLNSKMNAQNKLSLTQDPVVKVSEIVAKSKELDNFCNPIIYKPKPKAEVPEDKPKANSEH 806
Query: 927 EPPLNASASDQ 937
P++ + +
Sbjct: 807 NGPMDGQSGTE 817
>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
Length = 643
Score = 229 bits (585), Expect = 7e-60
Identities = 183/620 (29%), Positives = 295/620 (47%), Gaps = 63/620 (10%)
Query: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A S A NP
Sbjct: 9 VGIDLGTTYSCVGVFQQG-RVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHN 67
Query: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLN 155
T+ + L+G++ + V +P ++ + + F PEE+ MVL+
Sbjct: 68 TVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
Query: 156 YSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGV 215
+ AE + QP+K AVITVP +FN ++R+A A +AGL VL++IN+ TA A++YG+
Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
Query: 216 FRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEM 275
RR +N++ +D+G G+ ++++ +AG+ +++ D LGG +
Sbjct: 188 DRR---GAGERNVLIFDLGGGTFDVSVLSI------DAGV---FEVKATAGDTHLGGEDF 235
Query: 276 ELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMD 335
+ RL F E+ + + KD+ N RA+ +L R K LS++ +I+ L +
Sbjct: 236 D----NRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFE 291
Query: 336 DVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEV 395
VDF +TR FEELC+DLF PV++AL+ A++ +I V+LVGG+TR+P+VQ++
Sbjct: 292 GVDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKL 351
Query: 396 LLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFTREV 453
L +EL K+IN DEA A GA QAA L K KV+ ++ D V P+ +
Sbjct: 352 LQDFFNGKELNKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLD--VAPLSL------ 403
Query: 454 EEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGS 513
G+ + L R P ++ TF YS N + E R
Sbjct: 404 ----GLETAGGVMTTLIQRNATIPTKQTQTFTTYSD------NQPGVFIQVYEGERAMTK 453
Query: 514 QN--LTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEE 571
N L +L G+ + + P I+ F++D +G+LS+ T + S +
Sbjct: 454 DNNLLGRFELSGIPPAPRGVPQ-----IEVTFDIDANGILSV--------TATDRSTGKA 500
Query: 572 STLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVE 631
+ +T + N L +KE V E E+ AE ++V K EA V
Sbjct: 501 NKIT-ITNDKGRL--------SKEEVERMVHEAEQYKAEDEAQR--DRVAAKNSLEAHVF 549
Query: 632 DGSQPPPPEPKGDATPEGEK 651
E D PE ++
Sbjct: 550 HVKGSLQEESLRDKIPEEDR 569
Score = 50.4 bits (119), Expect = 8e-06
Identities = 56/273 (20%), Positives = 106/273 (38%), Gaps = 45/273 (16%)
Query: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
++ VL D+ E V + L+ D A L G +++L T K+ T T
Sbjct: 378 QAAVLMGDKCEKVQDLLLLDVAPLSLGLETAGGVMTTLIQRNATIPTKQTQTFTTY---- 433
Query: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659
S ++PG +++ E A +D + PP P+G P+ E + +
Sbjct: 434 -----SDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG--VPQIEVTFDID--- 483
Query: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719
G+ ++ A K + + G L ++++ +
Sbjct: 484 --------------ANGILSVTATDRSTGKANKITITNDKG---------RLSKEEVERM 520
Query: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779
V + + D +++R A NSLEA +F + L + ++ EE R ++ K
Sbjct: 521 VHEAEQYKAEDEAQRDRVAAKNSLEAHVFHVKGSLQEESLRDKIPEEDRRKMQDKCREVL 580
Query: 780 TWLEDEGVGATTVMLKEKLAELRKLCQGLFFRV 812
WLE + A + + EL ++C+ +F R+
Sbjct: 581 AWLEHNQL-AEKEEYEHQKRELEQICRPIFSRL 612
>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
Length = 646
Score = 227 bits (578), Expect = 5e-59
Identities = 174/599 (29%), Positives = 291/599 (48%), Gaps = 67/599 (11%)
Query: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP
Sbjct: 7 VGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
Query: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGMVL 154
T+ + L+G++ D+ V +P + D R V + + + F PEEV MVL
Sbjct: 66 TVFDAKRLIGRRFDDAVVQSDMKHWP-FMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
Query: 155 NYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYG 214
+ +AE + + + +AV+TVP +FN ++R+A A +AGL VL++IN+ TA A++YG
Sbjct: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
Query: 215 VFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLE 274
+ ++ +N++ +D+G G+ +I+T E G+ +++ D LGG +
Sbjct: 185 LDKKVGAE---RNVLIFDLGGGTFDVSILTI------EDGI---FEVKSTAGDTHLGGED 232
Query: 275 MELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM 334
+ R+ F + K KD+ EN RA+ +L R K LS++ +I+ L
Sbjct: 233 FDNRMVNHFIAEFKRKHK----KDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLY 288
Query: 335 DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQE 394
+ +DF +TR FEEL ADLF PV++AL+ A++ +I ++LVGG+TR+P++Q+
Sbjct: 289 EGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQK 348
Query: 395 VLLKAVGKEELGKNINADEAAAMGAVYQAAALS--KAFKVKPFVVRDAVVYPILVEFTRE 452
+L +EL K+IN DEA A GA QAA LS K+ V+ ++ D V P+ +
Sbjct: 349 LLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLD--VTPLSL----- 401
Query: 453 VEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHD---FNFHINYGDLGFLGPEDLR 509
GI + VL R P ++ TF YS + + G+ +L
Sbjct: 402 -----GIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNL- 455
Query: 510 VFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAE 569
L +L G+ + + P I+ F++D +G+L++ V+ E
Sbjct: 456 ------LGKFELTGIPPAPRGVPQ-----IEVTFDIDANGILNVSAVDK------STGKE 498
Query: 570 EESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEA 628
+ T+T +S KE+ VQE E+ AE K ++V K E+
Sbjct: 499 NKITITNDKGRLS-----------KEDIERMVQEAEKYKAEDEKQR--DKVSSKNSLES 544
Score = 42.0 bits (97), Expect = 0.003
Identities = 51/273 (18%), Positives = 106/273 (38%), Gaps = 45/273 (16%)
Query: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
++ +LS D+ E+V + L+ D + G ++ L TT K+ T T
Sbjct: 376 QAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTY---- 431
Query: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659
S ++PG +++ E A +D + PP P+G P+ E + +
Sbjct: 432 -----SDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG--VPQIEVTFDID--- 481
Query: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719
G+ +K K + + G L ++ + +
Sbjct: 482 --------------ANGILNVSAVDKSTGKENKITITNDKG---------RLSKEDIERM 518
Query: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779
VQ+ + D +++++ + NSLE++ F + + + Q +E +++I K +
Sbjct: 519 VQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEII 578
Query: 780 TWLEDEGVGATTVMLKEKLAELRKLCQGLFFRV 812
WL D+ A + + EL K+C + ++
Sbjct: 579 NWL-DKNQTAEKEEFEHQQKELEKVCNPIITKL 610
>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
Length = 493
Score = 222 bits (565), Expect = 2e-57
Identities = 146/456 (32%), Positives = 239/456 (52%), Gaps = 33/456 (7%)
Query: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP
Sbjct: 7 VGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 65
Query: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGMVL 154
T+ + L+G++ D+ V +P + D R V + + + F PEEV MVL
Sbjct: 66 TVFDAKRLIGRRFDDAVVQSDMKHWP-FMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVL 124
Query: 155 NYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYG 214
+ +AE + + + +AV+TVP +FN ++R+A A +AGL VL++IN+ TA A++YG
Sbjct: 125 TKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYG 184
Query: 215 VFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLE 274
+ ++ +N++ +D+G G+ +I+T E G+ +++ D LGG +
Sbjct: 185 LDKKVGAE---RNVLIFDLGGGTFDVSILTI------EDGI---FEVKSTAGDTHLGGED 232
Query: 275 MELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM 334
+ R+ F + K KD+ EN RA+ +L R K LS++ +I+ L
Sbjct: 233 FDNRMVNHFIAEFKRKHK----KDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLY 288
Query: 335 DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQE 394
+ +DF +TR FEEL ADLF PV++AL+ A++ +I ++LVGG+TR+P++Q+
Sbjct: 289 EGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQK 348
Query: 395 VLLKAVGKEELGKNINADEAAAMGAVYQAAALS--KAFKVKPFVVRDAVVYPILVEFTRE 452
+L +EL K+IN DEA A GA QAA LS K+ V+ ++ D V P+ +
Sbjct: 349 LLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLD--VTPLSL----- 401
Query: 453 VEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYS 488
GI + VL R P ++ TF YS
Sbjct: 402 -----GIETAGGVMTVLIKRNTTIPTKQTQTFTTYS 432
>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
Length = 641
Score = 222 bits (565), Expect = 2e-57
Identities = 155/526 (29%), Positives = 265/526 (50%), Gaps = 48/526 (9%)
Query: 34 AVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNP 93
A + +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP
Sbjct: 5 AAIGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNP 63
Query: 94 KATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGM 152
+ T+ + L+G++ +P V +P ++ D + V + + F PEE+ M
Sbjct: 64 QNTVFDAKRLIGRKFGDPVVQSDMKHWP-FQVINDGDKPKVQVSYKGETKAFYPEEISSM 122
Query: 153 VLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALS 212
VL + +AE + P+ +AVITVP +FN ++R+A A +AGL VL++IN+ TA A++
Sbjct: 123 VLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIA 182
Query: 213 YGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGG 272
YG+ R +N++ +D+G G+ +I+T + G+ +++ D LGG
Sbjct: 183 YGLDRT---GKGERNVLIFDLGGGTFDVSILTI------DDGI---FEVKATAGDTHLGG 230
Query: 273 LEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEG 332
+ + RL F E+ K + KD+ +N RA+ +L R K LS++ +I+
Sbjct: 231 EDFD----NRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDS 286
Query: 333 LMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRV 392
L + +DF +TR FEELC+DLF PV++AL+ A++ +I ++LVGG+TR+P+V
Sbjct: 287 LFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKV 346
Query: 393 QEVLLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFT 450
Q++L +L K+IN DEA A GA QAA L K+ V+ ++ D V P+ +
Sbjct: 347 QKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLD--VAPLSL--- 401
Query: 451 REVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHD---FNFHINYGDLGFLGPED 507
G+ + L R P ++ F YS + + G+ +
Sbjct: 402 -------GLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNN 454
Query: 508 LRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSL 553
L L +L G+ + + P I+ F++D +G+L++
Sbjct: 455 L-------LGRFELSGIPPAPRGVPQ-----IEVTFDIDANGILNV 488
Score = 39.7 bits (91), Expect = 0.014
Identities = 51/266 (19%), Positives = 102/266 (38%), Gaps = 45/266 (16%)
Query: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
++ +L D+ E+V + L+ D A L G +++L +T K+ T
Sbjct: 376 QAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTY---- 431
Query: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659
S ++PG +++ E A +D + PP P+G P+ E + +
Sbjct: 432 -----SDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG--VPQIEVTFDID--- 481
Query: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719
G+ +K A K + + G L ++++ +
Sbjct: 482 --------------ANGILNVTATDKSTGKANKITITNDKG---------RLSKEEIERM 518
Query: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779
VQ+ + D ++ER A N+LE++ F + + + +E ++++ K
Sbjct: 519 VQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVI 578
Query: 780 TWLEDEGVGATTVMLKEKLAELRKLC 805
+WL D A + K EL ++C
Sbjct: 579 SWL-DANTLAEKDEFEHKRKELEQVC 603
>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
Length = 641
Score = 222 bits (565), Expect = 2e-57
Identities = 155/526 (29%), Positives = 265/526 (50%), Gaps = 48/526 (9%)
Query: 34 AVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNP 93
A + +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP
Sbjct: 5 AAIGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNP 63
Query: 94 KATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGM 152
+ T+ + L+G++ +P V +P ++ D + V + + F PEE+ M
Sbjct: 64 QNTVFDAKRLIGRKFGDPVVQSDMKHWP-FQVINDGDKPKVQVSYKGETKAFYPEEISSM 122
Query: 153 VLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALS 212
VL + +AE + P+ +AVITVP +FN ++R+A A +AGL VL++IN+ TA A++
Sbjct: 123 VLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIA 182
Query: 213 YGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGG 272
YG+ R +N++ +D+G G+ +I+T + G+ +++ D LGG
Sbjct: 183 YGLDRT---GKGERNVLIFDLGGGTFDVSILTI------DDGI---FEVKATAGDTHLGG 230
Query: 273 LEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEG 332
+ + RL F E+ K + KD+ +N RA+ +L R K LS++ +I+
Sbjct: 231 EDFD----NRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDS 286
Query: 333 LMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRV 392
L + +DF +TR FEELC+DLF PV++AL+ A++ +I ++LVGG+TR+P+V
Sbjct: 287 LFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKV 346
Query: 393 QEVLLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFT 450
Q++L +L K+IN DEA A GA QAA L K+ V+ ++ D V P+ +
Sbjct: 347 QKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLD--VAPLSL--- 401
Query: 451 REVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHD---FNFHINYGDLGFLGPED 507
G+ + L R P ++ F YS + + G+ +
Sbjct: 402 -------GLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNN 454
Query: 508 LRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSL 553
L L +L G+ + + P I+ F++D +G+L++
Sbjct: 455 L-------LGRFELSGIPPAPRGVPQ-----IEVTFDIDANGILNV 488
Score = 39.7 bits (91), Expect = 0.014
Identities = 51/266 (19%), Positives = 102/266 (38%), Gaps = 45/266 (16%)
Query: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
++ +L D+ E+V + L+ D A L G +++L +T K+ T
Sbjct: 376 QAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTY---- 431
Query: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGS-------QPPPPEPKGDATPEGEKATEKENGD 659
S ++PG +++ E A +D + PP P+G P+ E + +
Sbjct: 432 -----SDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRG--VPQIEVTFDID--- 481
Query: 660 KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQS 719
G+ +K A K + + G L ++++ +
Sbjct: 482 --------------ANGILNVTATDKSTGKANKITITNDKG---------RLSKEEIERM 518
Query: 720 VQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAAS 779
VQ+ + D ++ER A N+LE++ F + + + +E ++++ K
Sbjct: 519 VQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVI 578
Query: 780 TWLEDEGVGATTVMLKEKLAELRKLC 805
+WL D A + K EL ++C
Sbjct: 579 SWL-DANTLAEKDEFEHKRKELEQVC 603
>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
Length = 641
Score = 219 bits (559), Expect = 8e-57
Identities = 143/455 (31%), Positives = 235/455 (51%), Gaps = 31/455 (6%)
Query: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP+
Sbjct: 9 IGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQN 67
Query: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVLGMVLN 155
T+ + L+G++ ++P V +P + + + + F PEE+ MVL
Sbjct: 68 TVFDAKRLIGRKFNDPVVQADMKLWPFQVINEGGKPKVLVSYKGENKAFYPEEISSMVLT 127
Query: 156 YSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYGV 215
+ AE F P+ +AVITVP +FN ++R+A A +AGL VL++IN+ TA A++YG+
Sbjct: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
Query: 216 FRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLEM 275
+ ++++ +D+G G+ +I+T + G+ +++ D LGG +
Sbjct: 188 DKG---GQGERHVLIFDLGGGTFDVSILTI------DDGI---FEVKATAGDTHLGGEDF 235
Query: 276 ELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLMD 335
+ RL F E+ K + KD+ +N RA+ +L R K LS++ +I+ L +
Sbjct: 236 D----NRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQANLEIDSLYE 291
Query: 336 DVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQEV 395
+DF +TR FEELCADLF PV++AL+ A+M +I ++LVGG+TR+P+VQ +
Sbjct: 292 GIDFYTSITRARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRL 351
Query: 396 LLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFTREV 453
L +L K+IN DEA A GA QAA L K+ KV+ ++ D V P+ +
Sbjct: 352 LQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLD--VAPLSL------ 403
Query: 454 EEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYS 488
G+ + L R P ++ F YS
Sbjct: 404 ----GLETAGGVMTALIKRNSTIPTKQTQIFTTYS 434
>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
Length = 639
Score = 215 bits (547), Expect = 2e-55
Identities = 159/546 (29%), Positives = 274/546 (50%), Gaps = 54/546 (9%)
Query: 36 MSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKA 95
+ +DLG+ V + + G +EI+ N + R TP V + ER GD+A + NP
Sbjct: 8 IGIDLGTTYSCVGVFQHG-KVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTN 66
Query: 96 TLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISSQLQ-FSPEEVLGMVL 154
T+ + L+G++ ++ V +P + + + V + + + F PEE+ MVL
Sbjct: 67 TIFDAKRLIGRKFEDATVQSDMKHWP-FRVVSEGGKPKVQVEYKGETKTFFPEEISSMVL 125
Query: 155 NYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATALSYG 214
+ +AE + + AVITVP +FN ++R+A A + GL VL++IN+ TA A++YG
Sbjct: 126 TKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYG 185
Query: 215 VFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTLGGLE 274
+ +K +N++ +D+G G+ +I+T E G+ +++ D LGG +
Sbjct: 186 L-DKKGCAGGEKNVLIFDLGGGTFDVSILTI------EDGI---FEVKSTAGDTHLGGED 235
Query: 275 MELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQIEGLM 334
+ R+ LA F + K KD+ N RA+ +L R K LS++ +I+ L
Sbjct: 236 FDNRMVSHLAEEFKRKHK----KDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLY 291
Query: 335 DDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPRVQE 394
+ VDF +TR FEEL ADLF PV++AL+ A++ +I++++LVGG+TR+P++Q+
Sbjct: 292 EGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQK 351
Query: 395 VLLKAVGKEELGKNINADEAAAMGAVYQAAAL--SKAFKVKPFVVRDAVVYPILVEFTRE 452
+L +EL K+IN DEA A GA QAA L K+ V+ ++ D V P+ +
Sbjct: 352 LLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLD--VTPLSL----- 404
Query: 453 VEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFN---FHINYGDLGFLGPEDLR 509
GI + L R P ++ TF YS + + + G+ +D
Sbjct: 405 -----GIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAM--TKDNN 457
Query: 510 VFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAE 569
+ G +LT G+ + + P I+ F++D +G+L++ T + S
Sbjct: 458 LLGKFDLT-----GIPPAPRGVPQ-----IEVTFDIDANGILNV--------TAADKSTG 499
Query: 570 EESTLT 575
+E+ +T
Sbjct: 500 KENKIT 505
Score = 34.3 bits (77), Expect = 0.60
Identities = 50/266 (18%), Positives = 99/266 (37%), Gaps = 31/266 (11%)
Query: 547 ESGVLSLDRVESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEE 606
++ +L D+ E+V + L+ D + G ++ L TT K+ T T + +
Sbjct: 379 QAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQ 438
Query: 607 SPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKP 666
S E GE+ K+ D + PP P+G P+ E + +
Sbjct: 439 SSVLVQVYE-GERAMTKDNNLLGKFDLTGIPPA-PRG--VPQIEVTFDID---------- 484
Query: 667 SEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDL 726
G+ +K K + + G L +D + + VQ+ +
Sbjct: 485 -------ANGILNVTAADKSTGKENKITITNDKG---------RLSKDDIDRMVQEAERY 528
Query: 727 TLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEG 786
D ++R A N+LE++ + + + + + +E+ + +I K WL D
Sbjct: 529 KSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWL-DRN 587
Query: 787 VGATTVMLKEKLAELRKLCQGLFFRV 812
A + K EL ++C + ++
Sbjct: 588 QMAEKDEYEHKQKELERVCNPIISKL 613
>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
Length = 654
Score = 207 bits (526), Expect = 5e-53
Identities = 128/400 (32%), Positives = 213/400 (53%), Gaps = 22/400 (5%)
Query: 31 DTLAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLK-ENERFFGDSAASMA 89
D V+ +DLG+ V + K G +EI+ N + R TP V E ER GD+A +
Sbjct: 26 DVGTVVGIDLGTTYSCVGVFKNG-RVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQL 84
Query: 90 IKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISS--QLQFSPE 147
NP+ T+ + L+G+ ++P V +F ++ + + I F+PE
Sbjct: 85 TSNPENTVFDAKRLIGRTWNDPSVQ-QDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPE 143
Query: 148 EVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNT 207
E+ MVL + AE + + + AV+TVP +FN A+R+A A +AGL V+++IN+ T
Sbjct: 144 EISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPT 203
Query: 208 ATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFD 267
A A++YG+ +R+ +NI+ +D+G G+ +++T ++ D
Sbjct: 204 AAAIAYGLDKREG----EKNILVFDLGGGTFDVSLLTID---------NGVFEVVATNGD 250
Query: 268 RTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHM 327
LGG + + R+ E L+ K + KDVR++ RA+ KL RE + K LS+
Sbjct: 251 THLGGEDFDQRVMEHFIKLY----KKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQAR 306
Query: 328 AQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGAT 387
+IE + DF +TR +FEEL DLF PVQ+ L+ +++ +I++++LVGG+T
Sbjct: 307 IEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGST 366
Query: 388 RVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALS 427
R+P++Q+++ + +E + IN DEA A GA QA LS
Sbjct: 367 RIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLS 406
>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
Length = 679
Score = 168 bits (425), Expect = 3e-41
Identities = 120/401 (29%), Positives = 202/401 (50%), Gaps = 32/401 (7%)
Query: 34 AVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLK-ENERFFGDSAASMAIKN 92
AV+ +DLG+ + VA+++ G +++ N E R TP +V + ER G A A+ N
Sbjct: 54 AVVGIDLGTTNSCVAVME-GKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTN 112
Query: 93 PKATLRYFQHLLGKQADNPHVA--LYQARFPEHELTFDPQRQTVHFQISSQLQFSPEEVL 150
P T + L+G++ D+P V + F + H ++ +SP ++
Sbjct: 113 PNNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEAHGKL-----YSPSQIG 167
Query: 151 GMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTATA 210
VL + AE++ K+AVITVP +FN ++R+A A +++GL VL++IN+ TA A
Sbjct: 168 AFVLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAA 227
Query: 211 LSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRTL 270
L+YG+ + +D + I YD+G G+ +I+ Q + +++ D L
Sbjct: 228 LAYGLDKSED-----KVIAVYDLGGGTFDISILEIQ---------KGVFEVKSTNGDTFL 273
Query: 271 GGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQI 330
GG + + L + F K + D+ ++ A+ ++ A + K LS++ +
Sbjct: 274 GGEDFDQALLRHIVKEF----KRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINL 329
Query: 331 EGLMDDVD----FKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGA 386
L D K+TR +FE + DL R P Q+A+Q AE+S +I +VILVGG
Sbjct: 330 PYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGM 389
Query: 387 TRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALS 427
TR+P+VQ+ + G+ K +N DEA A+GA Q L+
Sbjct: 390 TRMPKVQQTVQDLFGRAP-SKAVNPDEAVAIGAAIQGGVLA 429
>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
Length = 509
Score = 154 bits (388), Expect = 5e-37
Identities = 114/397 (28%), Positives = 188/397 (47%), Gaps = 22/397 (5%)
Query: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
+A + V LG S VA+ K G +V N R TP +V ENE G +A I+N
Sbjct: 1 MAAIGVHLGCTSACVAVYKDG-RAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRN 59
Query: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQRQTVHFQISS--QLQF-SPEEV 149
T+ + +LG+ + +P Y A E + + + ++I + + +F +PE+V
Sbjct: 60 ISNTVMKVKQILGRSSSDPQAQKYIA---ESKCLVIEKNGKLRYEIDTGEETKFVNPEDV 116
Query: 150 LGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLINDNTAT 209
++ + + A D VITVP F + ++ A+ +AAR AG VL+LI++ +A
Sbjct: 117 ARLIFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAA 176
Query: 210 ALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRGVGFDRT 269
L+YG+ +D T NI+ + +G S +++ +G+ ++ D
Sbjct: 177 LLAYGI--GQDSPTGKSNILVFKLGGTSLSLSVMEVN------SGIY---RVLSTNTDDN 225
Query: 270 LGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSANADHMAQ 329
+GG L + LA F K DVR N RAM KL A K LS
Sbjct: 226 IGGAHFTETLAQYLASEFQRSFK----HDVRGNARAMMKLTNSAEVAKHSLSTLGSANCF 281
Query: 330 IEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRV 389
++ L + DF V+R FE LC+ LF + ++ L + D+I +V+L GG++R+
Sbjct: 282 LDSLYEGQDFDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRI 341
Query: 390 PRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAAL 426
P++Q+++ EL +I DE +GA +A L
Sbjct: 342 PKLQQLIKDLFPAVELLNSIPPDEVIPIGAAIEAGIL 378
>gi|48928056 heat shock protein 70kDa family member 13 precursor
[Homo sapiens]
Length = 471
Score = 137 bits (345), Expect = 5e-32
Identities = 118/452 (26%), Positives = 216/452 (47%), Gaps = 63/452 (13%)
Query: 17 ALVAVLLADLLALS----DTLAVMSVDLGSESMKVAIVKPGV-PMEIVLNKESRRKTPVI 71
A++ +LLA LA T V+ +DLG+ V + PG ++++ ++ P +
Sbjct: 11 AVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSM 70
Query: 72 VTLKENERFFGDSAASMAIKNPKATLRYFQHLLGKQADNPHVALYQARFPEHELTFDPQR 131
V+ +N+ + G + +A NP+ T+ + +GK + R+P L +
Sbjct: 71 VSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLN---KN 127
Query: 132 QTVHFQISSQ--LQFSPEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVL 189
V F ++S + SPE V +L + +AE + P+ +AVI+VP F+ +R + +
Sbjct: 128 GMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTI 187
Query: 190 QAARMAGLKVLQLINDNTATALSYGVFRRKDINTTAQNIMFYDMGSGSTVCTIVTYQMVK 249
+AA +AGLK+L++IN+ TA A++YG+ + +++ D+G G+ +++
Sbjct: 188 EAANLAGLKILRVINEPTAAAMAYGLHK-----ADVFHVLVIDLGGGTLDVSLL------ 236
Query: 250 TKEAGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQR--KGQRAKDVRENPRA-- 305
K+ GM R + + LGG + RL + L + R +++ +A
Sbjct: 237 NKQGGM---FLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVE 293
Query: 306 MAKL---LREANRL----------------------KTVLSANADHMAQI---EGLMD-- 335
M KL L ++ +L K LS+ DH GL D
Sbjct: 294 MVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKK 353
Query: 336 ----DVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVILVGGATRVPR 391
V F+ +++R F+ L DLF+++ P+QQ L+ + EI++V+LVGG+TR+PR
Sbjct: 354 SGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPR 413
Query: 392 VQEVLLKAVGKEELGKNINADEAAAMGAVYQA 423
+++V+ + GK+ +++ D A G QA
Sbjct: 414 IRQVIQEFFGKDP-NTSVDPDLAVVTGVAIQA 444
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 60.5 bits (145), Expect = 8e-09
Identities = 95/434 (21%), Positives = 165/434 (38%), Gaps = 60/434 (13%)
Query: 595 ENGTDTVQEEEESPAEGSKDEPG-----EQVELKEEAEAPVEDGSQPPP----PEPKGDA 645
E +EE +SPAE E E+ + EA++PV++ ++ P PE
Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641
Query: 646 TPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVV 705
T E K+ EK + E K EKA++ + A +P EK + P + E
Sbjct: 642 TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSP--EKAKSPVKAEAKSPEKAKS--- 696
Query: 706 LDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTE 765
P + A+S +K + + + E+ K+ EA +T +K P +E +
Sbjct: 697 ------PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA---KTPEKAKSPVKEEAKSP 747
Query: 766 EQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSAL 825
E+ K + L+ + A T +E + K + V+E K PE+ A
Sbjct: 748 EK-----AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEK--AK 800
Query: 826 DNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPAT---- 881
L + + IP+ +++ + V+ E+ E + AE+ K PAT
Sbjct: 801 SPLKEDAK---APEKEIPKKEEVKSPVKE---EEKPQEVKVKEPPKKAEEEKAPATPKTE 854
Query: 882 ---------------EKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRA 926
KP + K A + +V+ +A+ K P P+ + +
Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKV 914
Query: 927 EPPLNASASDQGEKVIPPAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPE---- 982
E +A ++ E + EP EK E E DT+ + P +P+
Sbjct: 915 EVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAK 974
Query: 983 -QKEQSTGQKRPLK 995
+++ T K P K
Sbjct: 975 AKEDDKTLSKEPSK 988
Score = 56.6 bits (135), Expect = 1e-07
Identities = 96/423 (22%), Positives = 160/423 (37%), Gaps = 47/423 (11%)
Query: 598 TDTVQEEEESPA---EGSKDEPGEQVELK---EEAEAPVEDGSQPPPPEPKGDATPEGEK 651
T+ V EEEE A EG ++E GE+ E + EE ++P + + P E K E +
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526
Query: 652 ATEKENGDKSEAQKPSE-----------KAEAGPEGVAPAPEGEKKQKPA------RKRR 694
E ++ +K EA+ P+E K EA A +PE E+ + PA + +
Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS 586
Query: 695 MVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKL 754
+E P+ + + + + + E+ + S E T+++
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646
Query: 755 YQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEE 814
PE + +E+ + S + + V + K E K V+E
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK------SPVKE 700
Query: 815 RKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAE 874
K PE+ + +K PE + + E T EK ++ + A E
Sbjct: 701 EAKSPEKAKSP----------VKEEAKSPEKAKSPVKEEAKTPEKA--KSPVKEEAKSPE 748
Query: 875 QAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASA 934
+AK P K L K EAK A + + K + + K+ +A+ PL A
Sbjct: 749 KAKSPEKAK-TLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDA 807
Query: 935 SDQGEKVIPPAGQTEDAEPISEPEKVE--TGSEPGDTEPLELGGPGAEPEQKEQSTGQKR 992
EK IP + E P+ E EK + EP E + E+K+ S ++
Sbjct: 808 K-APEKEIPK--KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA 864
Query: 993 PLK 995
P K
Sbjct: 865 PKK 867
Score = 47.8 bits (112), Expect = 5e-05
Identities = 85/407 (20%), Positives = 152/407 (37%), Gaps = 49/407 (12%)
Query: 592 DAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEK 651
+ E T V+E+ E + + E+V +EE EA E+G + EG +
Sbjct: 448 EKSEKETVIVEEQTE------ETQVTEEVTEEEEKEAKEEEGKEE-----------EGGE 490
Query: 652 ATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDL 711
E E G++ P+E+A A PE A +P E+ + PA + +E + P+
Sbjct: 491 EEEAEGGEEETKSPPAEEA-ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE- 548
Query: 712 PEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEI 771
A+S K + + + + E+E+A + E ++ +K P +E + + +
Sbjct: 549 ----KAKSPAKEEAKSPPEAKSPEKEEAKSPAEV---KSPEKAKSPAKEEAKSPAEAKSP 601
Query: 772 SGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNH 831
S + + V + K K + +E K PE+ + +
Sbjct: 602 EKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE----- 656
Query: 832 SSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDI 891
K PE + + E + EK + A A E+AK P E+ +K
Sbjct: 657 -----KEEAKSPEKAKSPVKAEAKSPEKAKSPVKA--EAKSPEKAKSPVKEE----AKSP 705
Query: 892 EAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDA 951
E + E + + K + + K +A+ P+ A + P +T D
Sbjct: 706 EKAKSPVKEEAK----SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761
Query: 952 E-PISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKRPLKND 997
+ P ++ E P D P + P E + + K PLK D
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKA--KSPLKED 806
Score = 38.9 bits (89), Expect = 0.024
Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 25/152 (16%)
Query: 594 KENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKAT 653
KE+ + +EE E ++ + P + P E K DA P+ +
Sbjct: 886 KESKVEAKKEEAE-----------------DKKKVPTPEKEAPAKVEVKEDAKPKEKTEV 928
Query: 654 EKENGDKSEAQ---KPSEKAEAGPEGVAPAPEGEKK--QKPARKRRMVEEIGVELVVLDL 708
K+ D ++A+ KP+EK EA PE E KK +KP + + E+ + +
Sbjct: 929 AKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED---DKTLSKE 985
Query: 709 PDLPEDKLAQSVQKLQDLTLRDLEKQEREKAA 740
P P+ + A+ + EK +KAA
Sbjct: 986 PSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 36.6 bits (83), Expect = 0.12
Identities = 45/188 (23%), Positives = 69/188 (36%), Gaps = 14/188 (7%)
Query: 594 KENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQ------PPPPEPKGDATP 647
KE V+EEE+ K+ P + E K A E+ P PK
Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876
Query: 648 EGEKATEKENGDKSEAQK---PSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELV 704
+ E A EK K EA+K +K PE APA K+ +++ V + +
Sbjct: 877 KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 936
Query: 705 VLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVST 764
P P +K + +K T + K+ EK +A + DK E +
Sbjct: 937 KAKEPSKPAEKKEAAPEKKD--TKEEKAKKPEEKPKTEAKA---KEDDKTLSKEPSKPKA 991
Query: 765 EEQREEIS 772
E+ + S
Sbjct: 992 EKAEKSSS 999
Score = 35.4 bits (80), Expect = 0.27
Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
Query: 592 DAKENGTDTVQEEEESPAEGSK-DEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGE 650
DAK V ++E A+ + +P E+ E E + E+ ++ P +PK +A + +
Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKED 978
Query: 651 KATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPAR 691
T + K +A+K +EK+ + + + PE + K A+
Sbjct: 979 DKTLSKEPSKPKAEK-AEKSSSTDQKDSKPPEKATEDKAAK 1018
Score = 34.3 bits (77), Expect = 0.60
Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 13/90 (14%)
Query: 590 TPDAKENGTDTVQEEEESPAE---------GSKDEPGEQVELKEEAEAPVEDGSQPPPPE 640
T AK+ D +E PAE +K+E ++ E K + EA ++ + E
Sbjct: 926 TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Query: 641 PKGDATPEGEKATEKENGDKSEAQKPSEKA 670
P + P+ EKA + + D+ ++ KP EKA
Sbjct: 986 P---SKPKAEKAEKSSSTDQKDS-KPPEKA 1011
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 54.3 bits (129), Expect = 6e-07
Identities = 114/479 (23%), Positives = 167/479 (34%), Gaps = 80/479 (16%)
Query: 512 GSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEE 571
GSQ L K +G++ E +G K H N + S L E E + E
Sbjct: 1748 GSQRLNRDKDPKLGEAEGDAMAQEREG-KTH-NSETSAGSELGEAEQEGEGISERGETGG 1805
Query: 572 STLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVE 631
N GG + +G + ++ E AEG E VE E AE +
Sbjct: 1806 QGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPE---AEGEAQPESEGVEAPE-AEGDAQ 1861
Query: 632 DGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGV-APAPEGEKKQKPA 690
+ PE + PE E + E+ D + P + E PE A APE EK+ +P
Sbjct: 1862 EAEGEAQPESEDVEAPEAEGEAQPESED---VETPEAEWEVQPESEGAEAPEAEKEAQP- 1917
Query: 691 RKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFET 750
E VE + + D PE + A E QE E+AA E
Sbjct: 1918 ------ETESVEALETEGEDEPESEGA--------------EAQEAEEAAQEAEG----- 1952
Query: 751 QDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFF 810
QPE + + ++E EE E E V A V ++ + AE G
Sbjct: 1953 ---QTQPESEVIESQEAEEEAQP---------ESEDVEALEVEVETQEAE------GEAQ 1994
Query: 811 RVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTTLEKVINETWAWKNA 870
E + PE + + G P+ E ++V ET +
Sbjct: 1995 PESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKS-------EGEEAQEVEGETQKTEGD 2047
Query: 871 TLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRPRPKDKNGTRAEPPL 930
E + A E E + + EVQ +A P +D + AE
Sbjct: 2048 AQPESDGVEAPE--------AEEEAQEAEGEVQEAEGEA-----HPESEDVDAQEAEG-- 2092
Query: 931 NASASDQGEKVIPPAGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTG 989
A +G + G+ + AE I PE G ++E +E P AE E + +S G
Sbjct: 2093 EAQPESEGVEAPEAEGEAQKAEGIEAPE--TEGEAQPESEGIE--APEAEGEAQPESEG 2147
Score = 42.4 bits (98), Expect = 0.002
Identities = 40/189 (21%), Positives = 75/189 (39%), Gaps = 18/189 (9%)
Query: 591 PDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGE 650
P+A E +EE + ++G + +P + E +E E + PE G PE E
Sbjct: 2003 PEA-EGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAE 2061
Query: 651 KATEKENGD----KSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVL 706
+ ++ G+ + EA SE +A PE E + P + + G+E
Sbjct: 2062 EEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPET 2121
Query: 707 DLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEE 766
+ PE + ++ + + E + + +EA + + QPE + + +E
Sbjct: 2122 EGEAQPESEGIEAPE----------AEGEAQPESEGVEA---QDAEGEAQPESEGIEAQE 2168
Query: 767 QREEISGKL 775
EE +L
Sbjct: 2169 AEEEAQPEL 2177
Score = 41.6 bits (96), Expect = 0.004
Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 8/110 (7%)
Query: 587 GGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDAT 646
G P+A+ + E AEG E +E +E E + PE +G+A
Sbjct: 2131 GIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQ 2190
Query: 647 PEGE--KATEKENG-----DKSEAQKPSEKAEAGPEGVAPAPEGEKKQKP 689
PE E +A E E + EA + E+A+ PEGV PE E + +P
Sbjct: 2191 PESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGV-ETPEAEGEAQP 2239
Score = 41.6 bits (96), Expect = 0.004
Identities = 31/115 (26%), Positives = 46/115 (40%), Gaps = 16/115 (13%)
Query: 592 DAKENGTDTVQEEEESPAEGSKDEPGEQVELKEE----------AEAP-VEDGSQPPP-- 638
+A+E ++ E AEG E +E E EAP E+ +QP P
Sbjct: 2168 EAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEG 2227
Query: 639 ---PEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPA 690
PE +G+A PE E T+ E + ++E E +P PE P+
Sbjct: 2228 VETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPS 2282
Score = 40.4 bits (93), Expect = 0.008
Identities = 32/117 (27%), Positives = 53/117 (45%), Gaps = 15/117 (12%)
Query: 587 GGTTPDAKENGTDTVQEEEESPAEGSKDEPGE-QVELKEEAEAPVEDGSQPPP------P 639
G P++++ + E + +EG + E + + E EAP +G P P
Sbjct: 2076 GEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAP 2135
Query: 640 EPKGDATPEGE-------KATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKP 689
E +G+A PE E + + + EAQ+ E+A+ EGV APE E + +P
Sbjct: 2136 EAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGV-EAPEAEGEAQP 2191
Score = 39.7 bits (91), Expect = 0.014
Identities = 56/209 (26%), Positives = 93/209 (44%), Gaps = 28/209 (13%)
Query: 557 ESVFETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEES--------- 607
E++ E L E+ EE ++ G +S ++PD K + D +EEE+
Sbjct: 1388 EALEEGLKEEGLPEEGSVH--GQELSE----ASSPDGKGSQEDDPVQEEEAGRASASAEP 1441
Query: 608 -PAEGSKD--EPGEQVELKEEAEAPVEDGSQPPP--PEPKGDATPEGEKATEKE----NG 658
PAEG+++ EP + + + + + GSQ P +P G AT G++ T+ +
Sbjct: 1442 CPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPG-ATMMGQEHTQAQPTQGAA 1500
Query: 659 DKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVE--LVVLDLPDLPEDKL 716
++S + S + P V+ + +K A V E+ L DL D +L
Sbjct: 1501 ERSSSVACSAALDCDPIWVSVLLKKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAEL 1560
Query: 717 AQSV-QKLQDLTLRDLEKQEREKAANSLE 744
Q V Q+LQD T R+L+K + LE
Sbjct: 1561 QQDVAQRLQDSTKRELQKLQGRAGRMVLE 1589
Score = 36.2 bits (82), Expect = 0.16
Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 611 GSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKA 670
G + +PG+ L+ E P + G Q +P D PEG + G +S P
Sbjct: 989 GPEVDPGDDHSLEGLGE-PAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQ--- 1044
Query: 671 EAGPEGV--APAPEGEKKQKPA 690
A PEGV APA G ++ PA
Sbjct: 1045 GAAPEGVSEAPAEAGADREAPA 1066
Score = 35.4 bits (80), Expect = 0.27
Identities = 44/199 (22%), Positives = 81/199 (40%), Gaps = 19/199 (9%)
Query: 587 GGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDAT 646
G P+++ + E + +EG + + E E ++ + PE +G
Sbjct: 2123 GEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEA 2182
Query: 647 PEGEKATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVL 706
PE E + E+ + EA + +A+ EGV APE E++ +P E GVE
Sbjct: 2183 PEAEGEAQPES-EGIEAPEAEGEAQPELEGV-EAPEAEEEAQP-------EPEGVETPEA 2233
Query: 707 DLPDLPEDKLAQSVQK--LQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVST 764
+ PE + +K ++L D + +E ++++ + +D+ P T
Sbjct: 2234 EGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPV------PEDRPTPPPSPGGDT 2287
Query: 765 EEQR--EEISGKLSAASTW 781
QR + S AS+W
Sbjct: 2288 PHQRPGSQTGPSSSRASSW 2306
Score = 32.3 bits (72), Expect = 2.3
Identities = 35/131 (26%), Positives = 51/131 (38%), Gaps = 25/131 (19%)
Query: 535 ESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEEST---LTKLGNTISSLFGGGTTP 591
ES+GI+A +E L+ VE+ E A+ ES + G P
Sbjct: 2160 ESEGIEAQ-EAEEEAQPELEGVEA---PEAEGEAQPESEGIEAPEAEGEAQPELEGVEAP 2215
Query: 592 DAKEN------GTDTVQEEEESPAEGSKDEPGE------------QVELKEEAEAPVEDG 633
+A+E G +T + E E+ E + GE Q E E+ +PV +
Sbjct: 2216 EAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPED 2275
Query: 634 SQPPPPEPKGD 644
PPP P GD
Sbjct: 2276 RPTPPPSPGGD 2286
Score = 31.2 bits (69), Expect = 5.1
Identities = 42/152 (27%), Positives = 59/152 (38%), Gaps = 32/152 (21%)
Query: 540 KAHFNLDESGVLSLDRVESVFETLVEDSAEEESTLTKLGNT--------------ISSLF 585
K L E GV ++E ET E EEE+ L ++ T +
Sbjct: 1326 KTEEGLQEEGV----QLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGP 1381
Query: 586 GGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPP---EPK 642
GG +A E G +EE P EGS G+++ EA +P GSQ P E
Sbjct: 1382 EGGLQGEALEEGL----KEEGLPEEGSVH--GQELS---EASSPDGKGSQEDDPVQEEEA 1432
Query: 643 GDATPEGEKATEKENGDKSEAQKPSEKAEAGP 674
G A+ E + G + + PS +E P
Sbjct: 1433 GRASASAEPCPAE--GTEEPTEPPSHLSETDP 1462
>gi|70980549 programmed cell death 11 [Homo sapiens]
Length = 1871
Score = 52.8 bits (125), Expect = 2e-06
Identities = 67/290 (23%), Positives = 114/290 (39%), Gaps = 46/290 (15%)
Query: 581 ISSLFGGGTTPD---AKENGTDTVQEEEESPAEGSKDEPGEQVELK----------EEAE 627
+S L G PD A G T QEE ++ AE +D+ GE+ K EE E
Sbjct: 1393 LSFLPGDTGKPDVLSASLEGQLTKQEERKTEAE-ERDQKGEKKNQKRNEKKNQKGQEEVE 1451
Query: 628 APVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGP-----------EG 676
P ++ QP P+ A G + + ++ K +KA EG
Sbjct: 1452 MPSKEKQQPQKPQ----AQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREG 1507
Query: 677 VAPAPE-----GEKKQKPARKRRM------VEEIGVELVVLDLPDLPEDKLAQSVQKLQD 725
A E EK+ KPA R+ +G++ + LP L E ++ +K
Sbjct: 1508 KEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQ 1567
Query: 726 LTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDE 785
T++ K+ERE E + ++ L P Q S ++ + +++ WL+
Sbjct: 1568 ATIKK-SKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYM 1626
Query: 786 GVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMF 835
+++ A + + + FR E+ E+L+ LLN +M+
Sbjct: 1627 AFHLQATEIEKARAVAERALKTISFREEQ-----EKLNVWVALLNLENMY 1671
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 51.2 bits (121), Expect = 5e-06
Identities = 102/441 (23%), Positives = 173/441 (39%), Gaps = 63/441 (14%)
Query: 557 ESVFETLVEDSAEE-ESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDE 615
E + ET VED E E LT + ++ A+E + EEEE A+ S +
Sbjct: 455 EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVK 514
Query: 616 PGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPE 675
+EE E E+G + E EG K+ + E G SE + SEK E E
Sbjct: 515 ATAPEVKEEEGEKEEEEGQEEEEEE------DEGAKSDQAEEGG-SEKEGSSEKEEGEQE 567
Query: 676 GVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQE 735
E E ++ A++ + VEE E+ ++ + D + ++
Sbjct: 568 EGETEAEAEGEEAEAKEEKKVEEKSEEVAT------------------KEELVADAKVEK 609
Query: 736 REKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEG---VGATTV 792
EKA + + E + K P+ S E++ GK + +E++G V + V
Sbjct: 610 PEKAKSPVPKSPVEEKGKSPVPK----SPVEEK----GKSPVPKSPVEEKGKSPVPKSPV 661
Query: 793 MLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEV 852
K K + VEE+ K P S ++ + + + KG + E ++
Sbjct: 662 EEKGKSPVSKS-------PVEEKAKSPVPKSPVEEAKSKAEVG-KGEQKEEEEKEV---K 710
Query: 853 EMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNK--AK 910
E EKV + K+ ++A+ P E+ V A+++ + + V+ L K +
Sbjct: 711 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV-------AEVVTITKSVKVHLEKETKE 763
Query: 911 FTKPRPRPKDKNGTRAEPPLNASASDQGEK-----VIPPAGQTEDAEPISEPEKVETGSE 965
KP + K+K E SD+G K I G+ E E + E E E GS
Sbjct: 764 EGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEV-EQETKEKGSG 822
Query: 966 PGDTEPLELGGPGAEPEQKEQ 986
+ + + G P +++
Sbjct: 823 REEEKGVVTNGLDLSPADEKK 843
Score = 46.2 bits (108), Expect = 2e-04
Identities = 76/312 (24%), Positives = 130/312 (41%), Gaps = 51/312 (16%)
Query: 530 KYPDYESKGIKAHFNLDESGVLSL--DRVESVFETLVEDSAEEESTLTKLGNTISSLFGG 587
K D +S+ +A + E +S+ ++ E+ E E AEEE K +
Sbjct: 461 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKA----- 515
Query: 588 GTTPDAKEN--------GTDTVQEEEE-----------SPAEGSKD-EPGEQVELKEEAE 627
T P+ KE G + +EE+E S EGS + E GEQ E + EAE
Sbjct: 516 -TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAE 574
Query: 628 APVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSE------KAEAGPEGVAPAP 681
A +G + E K E AT++E ++ +KP + K+ +G +P P
Sbjct: 575 A---EGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 631
Query: 682 EG--EKKQKPARKRRMVEEIGVELVVLDLPDLP-EDKLAQSVQK--LQDLTLRDLEKQER 736
+ E+K K + VEE G V P P E+K V K +++ + K
Sbjct: 632 KSPVEEKGKSPVPKSPVEEKGKSPV----PKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 687
Query: 737 EKAANSLEAFIFETQDKLYQ-----PEYQEVSTEEQREEISGKLSAASTWLEDEGVGATT 791
E+A + E E +++ + P+ ++V +E++ + + A + +++E V
Sbjct: 688 EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVV 747
Query: 792 VMLKEKLAELRK 803
+ K L K
Sbjct: 748 TITKSVKVHLEK 759
Score = 35.8 bits (81), Expect = 0.21
Identities = 58/288 (20%), Positives = 113/288 (39%), Gaps = 18/288 (6%)
Query: 713 EDKLAQSVQKLQDLTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEIS 772
++++A+ ++LQ ++ +LE K + + E + YQ+ + + E
Sbjct: 314 KEEIAEYRRQLQSKSI-ELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRG 372
Query: 773 GKLSAASTWLEDEGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHS 832
K A E + + + L ++A RKL +G EE + S L H
Sbjct: 373 TKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEG-----EETRFSTFAGSITGPLYTHR 427
Query: 833 SMFLKGARLI-PEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDI 891
+++ P+++ +V+ +E++I ET + E+A TE+ + K+
Sbjct: 428 PPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKE- 486
Query: 892 EAKMMALDREVQ-------YLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPP 944
E K A ++E + K+ P K++ G + E ++ E
Sbjct: 487 EKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSD 546
Query: 945 AGQTEDAEPISEPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKR 992
+ +E EK E E G+T E G E E KE+ +++
Sbjct: 547 QAEEGGSEKEGSSEKEEGEQEEGET---EAEAEGEEAEAKEEKKVEEK 591
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 51.2 bits (121), Expect = 5e-06
Identities = 102/441 (23%), Positives = 173/441 (39%), Gaps = 63/441 (14%)
Query: 557 ESVFETLVEDSAEE-ESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDE 615
E + ET VED E E LT + ++ A+E + EEEE A+ S +
Sbjct: 79 EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVK 138
Query: 616 PGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPE 675
+EE E E+G + E EG K+ + E G SE + SEK E E
Sbjct: 139 ATAPEVKEEEGEKEEEEGQEEEEEE------DEGAKSDQAEEGG-SEKEGSSEKEEGEQE 191
Query: 676 GVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQE 735
E E ++ A++ + VEE E+ ++ + D + ++
Sbjct: 192 EGETEAEAEGEEAEAKEEKKVEEKSEEVAT------------------KEELVADAKVEK 233
Query: 736 REKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEG---VGATTV 792
EKA + + E + K P+ S E++ GK + +E++G V + V
Sbjct: 234 PEKAKSPVPKSPVEEKGKSPVPK----SPVEEK----GKSPVPKSPVEEKGKSPVPKSPV 285
Query: 793 MLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEV 852
K K + VEE+ K P S ++ + + + KG + E ++
Sbjct: 286 EEKGKSPVSKS-------PVEEKAKSPVPKSPVEEAKSKAEVG-KGEQKEEEEKEV---K 334
Query: 853 EMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNK--AK 910
E EKV + K+ ++A+ P E+ V A+++ + + V+ L K +
Sbjct: 335 EAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV-------AEVVTITKSVKVHLEKETKE 387
Query: 911 FTKPRPRPKDKNGTRAEPPLNASASDQGEK-----VIPPAGQTEDAEPISEPEKVETGSE 965
KP + K+K E SD+G K I G+ E E + E E E GS
Sbjct: 388 EGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEV-EQETKEKGSG 446
Query: 966 PGDTEPLELGGPGAEPEQKEQ 986
+ + + G P +++
Sbjct: 447 REEEKGVVTNGLDLSPADEKK 467
Score = 46.2 bits (108), Expect = 2e-04
Identities = 76/312 (24%), Positives = 130/312 (41%), Gaps = 51/312 (16%)
Query: 530 KYPDYESKGIKAHFNLDESGVLSL--DRVESVFETLVEDSAEEESTLTKLGNTISSLFGG 587
K D +S+ +A + E +S+ ++ E+ E E AEEE K +
Sbjct: 85 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKA----- 139
Query: 588 GTTPDAKEN--------GTDTVQEEEE-----------SPAEGSKD-EPGEQVELKEEAE 627
T P+ KE G + +EE+E S EGS + E GEQ E + EAE
Sbjct: 140 -TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAE 198
Query: 628 APVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSE------KAEAGPEGVAPAP 681
A +G + E K E AT++E ++ +KP + K+ +G +P P
Sbjct: 199 A---EGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 255
Query: 682 EG--EKKQKPARKRRMVEEIGVELVVLDLPDLP-EDKLAQSVQK--LQDLTLRDLEKQER 736
+ E+K K + VEE G V P P E+K V K +++ + K
Sbjct: 256 KSPVEEKGKSPVPKSPVEEKGKSPV----PKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 311
Query: 737 EKAANSLEAFIFETQDKLYQ-----PEYQEVSTEEQREEISGKLSAASTWLEDEGVGATT 791
E+A + E E +++ + P+ ++V +E++ + + A + +++E V
Sbjct: 312 EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVV 371
Query: 792 VMLKEKLAELRK 803
+ K L K
Sbjct: 372 TITKSVKVHLEK 383
Score = 33.1 bits (74), Expect = 1.3
Identities = 34/157 (21%), Positives = 63/157 (40%), Gaps = 11/157 (7%)
Query: 843 PEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREV 902
P+++ +V+ +E++I ET + E+A TE+ + K+ E K A ++E
Sbjct: 63 PKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKE-EKKEAAEEKEE 121
Query: 903 Q-------YLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAEPIS 955
+ K+ P K++ G + E ++ E + +E
Sbjct: 122 EPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEG 181
Query: 956 EPEKVETGSEPGDTEPLELGGPGAEPEQKEQSTGQKR 992
EK E E G+T E G E E KE+ +++
Sbjct: 182 SSEKEEGEQEEGET---EAEAEGEEAEAKEEKKVEEK 215
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 50.1 bits (118), Expect = 1e-05
Identities = 144/667 (21%), Positives = 235/667 (35%), Gaps = 132/667 (19%)
Query: 401 GKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVVYPILVEFTREVEEEPGIH 460
G+E K++ D + + + K VR+A + L E ++VE P I
Sbjct: 65 GQEMTSKSLQTDTIVEEKKEVKLVEETVVPEEKSADVREAAIE--LPESVQDVEIPPNIP 122
Query: 461 S--LKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGDLGFLGPEDLRVFGSQNLTT 518
S LK ++ SR G + + + + + + ++ + D S+
Sbjct: 123 SVQLKMDRSQQTSRTGYWTMMNIPPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKE-DA 181
Query: 519 VKLKGVGDSF-KKYPDYESKGIKAHFNLDESGVLSLDRVESVFET------LVEDSAEEE 571
+K K G F ++P+++ A + +E G ++ R ET L+ED EE
Sbjct: 182 LKHKSSGKIFASEHPEFQP----ATNSNEEIGQKNISRTSFTQETKKGPPVLLEDELREE 237
Query: 572 STLTKL--GNTISSLFGGGTTPDAKENGTDTVQ---------EEEESPAEGSKDEPGEQV 620
T+ + G+ + + P + E +Q + E PAE + +
Sbjct: 238 VTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPST 297
Query: 621 ELKEEAEAP--VEDGS---QPPPPE-------------PKGDATPEGEKATE--KENGDK 660
E +AEA V + S QPPP E P + +P E E + ++
Sbjct: 298 EETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEE 357
Query: 661 SEAQKP----------------------SEKAEAGPEGVAPAP-EGEKKQKPARKRRMVE 697
S +++P S A+ P V P P EG ++ PA+ VE
Sbjct: 358 SPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAK----VE 413
Query: 698 EIGVELVVLDL-PDLPEDKLAQSVQKLQDLTLRDLEKQE----------REKAANSLEAF 746
VE + D+ P LPE+ + ++LQ T + +E +E A A
Sbjct: 414 PPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAE 473
Query: 747 IF----------ETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKE 796
I ET + P +E S EE E+ L A T E+ + E
Sbjct: 474 IQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQSPL-AEETTAEEASAEIQLLAAIE 532
Query: 797 KLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGA-------RLIPEMDQIF 849
A+ E + E SA + S KG L P +
Sbjct: 533 APADETP--------AEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEET 584
Query: 850 TEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKA 909
T E + +++ T A AE PA E P EVQ +
Sbjct: 585 TAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPA---------------EVQPPPAEE 629
Query: 910 KFTKPRPRPKDKNGTRAEPPLNASASDQGEKVIPPAGQTEDAE---PISEPEKVETGSEP 966
+ +P P ++ +PP A + +V PP + AE P +E E S P
Sbjct: 630 APAEVQPPPAEEAPAEVQPP---PAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLP 686
Query: 967 GDTEPLE 973
+ P+E
Sbjct: 687 AEETPIE 693
Score = 30.8 bits (68), Expect = 6.6
Identities = 33/151 (21%), Positives = 58/151 (38%), Gaps = 10/151 (6%)
Query: 843 PEMDQIFTEVEMTTLEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREV 902
P +++ +V+ E+ E + L+ + PA E P + + A +
Sbjct: 415 PTVEETLADVQPLLPEEAPREEA--RELQLSTAMETPAEEAPTEFQSPLPKETTAEEASA 472
Query: 903 QYLLNKAKFTKPRPRPKDKNGTRAEPPLNASASDQ---GEKVIPPAGQTEDAEPISEPEK 959
+ L A T+P P D+ A PL+ S + E P A +T E +E +
Sbjct: 473 EIQLLAA--TEP---PADETPAEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQL 527
Query: 960 VETGSEPGDTEPLELGGPGAEPEQKEQSTGQ 990
+ P D P E P +E E++ +
Sbjct: 528 LAAIEAPADETPAEAQSPLSEETSAEEAPAE 558
>gi|225543215 antigen identified by monoclonal antibody Ki-67
isoform 2 [Homo sapiens]
Length = 2896
Score = 47.8 bits (112), Expect = 5e-05
Identities = 78/355 (21%), Positives = 131/355 (36%), Gaps = 47/355 (13%)
Query: 508 LRVFGSQNLTTVKLKGVGDSFKKY-PDYESKGIKAHFNLDESGVLSLDRVESVFETLVED 566
+ + S+NL + +G + P ES G F+ + D+ S L
Sbjct: 415 IAISNSENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKC-SASPPLRRQ 473
Query: 567 SAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEA 626
E + K + T+ + K + T+T E S + + G E +
Sbjct: 474 CIRENGNVAKTPRNTYKM----TSLETKTSDTET----EPSKTVSTANRSGRSTEFRNIQ 525
Query: 627 EAPVEDGSQPPPPEPKGDATPEGEKAT---EKENGDKSEAQKPSEKAEAGPEGVAPAPEG 683
+ PVE S+ E G+KAT ++ G+ E ++P E + E +
Sbjct: 526 KLPVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYK---ENIELKEND 582
Query: 684 EKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSL 743
EK + R R ++ + DL LP+ +L + + Q+L L+ Q+ KA S
Sbjct: 583 EKMKAMKRSRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNL----LQTQDHAKAPKSE 638
Query: 744 EAFIFETQDKLYQPEYQEVSTEEQ------------REEI--SGKLSAAS-----TWLED 784
+ I + + QPE T + +EE+ GK + S T E
Sbjct: 639 KGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREP 698
Query: 785 EGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWP----ERLSALDNLLNHSSMF 835
G G + KE ++ RV KKWP E +L++L +F
Sbjct: 699 AGDGKSIRTFKESPKQILDPAA----RVTGMKKWPRTPKEEAQSLEDLAGFKELF 749
>gi|103472005 antigen identified by monoclonal antibody Ki-67 isoform
1 [Homo sapiens]
Length = 3256
Score = 47.8 bits (112), Expect = 5e-05
Identities = 78/355 (21%), Positives = 131/355 (36%), Gaps = 47/355 (13%)
Query: 508 LRVFGSQNLTTVKLKGVGDSFKKY-PDYESKGIKAHFNLDESGVLSLDRVESVFETLVED 566
+ + S+NL + +G + P ES G F+ + D+ S L
Sbjct: 775 IAISNSENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKC-SASPPLRRQ 833
Query: 567 SAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEA 626
E + K + T+ + K + T+T E S + + G E +
Sbjct: 834 CIRENGNVAKTPRNTYKM----TSLETKTSDTET----EPSKTVSTANRSGRSTEFRNIQ 885
Query: 627 EAPVEDGSQPPPPEPKGDATPEGEKAT---EKENGDKSEAQKPSEKAEAGPEGVAPAPEG 683
+ PVE S+ E G+KAT ++ G+ E ++P E + E +
Sbjct: 886 KLPVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYK---ENIELKEND 942
Query: 684 EKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTLRDLEKQEREKAANSL 743
EK + R R ++ + DL LP+ +L + + Q+L L+ Q+ KA S
Sbjct: 943 EKMKAMKRSRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNL----LQTQDHAKAPKSE 998
Query: 744 EAFIFETQDKLYQPEYQEVSTEEQ------------REEI--SGKLSAAS-----TWLED 784
+ I + + QPE T + +EE+ GK + S T E
Sbjct: 999 KGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREP 1058
Query: 785 EGVGATTVMLKEKLAELRKLCQGLFFRVEERKKWP----ERLSALDNLLNHSSMF 835
G G + KE ++ RV KKWP E +L++L +F
Sbjct: 1059 AGDGKSIRTFKESPKQILDPAA----RVTGMKKWPRTPKEEAQSLEDLAGFKELF 1109
>gi|24308394 hypothetical protein LOC140893 [Homo sapiens]
Length = 664
Score = 47.4 bits (111), Expect = 7e-05
Identities = 43/137 (31%), Positives = 54/137 (39%), Gaps = 26/137 (18%)
Query: 590 TPDAKENGTDTV----QEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQP-PPPEPKG- 643
+P A NGT QEE +P + S+ PG Q+ L ED +P PPP P+
Sbjct: 487 SPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPP 546
Query: 644 --------DATPEGEKA--TEKENGDKSEAQKP------SEKAEAGPEGVAPAPE----G 683
D PE KA E+ + E P S +AEA PE
Sbjct: 547 PHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQ 606
Query: 684 EKKQKPARKRRMVEEIG 700
E Q P RKR+ E G
Sbjct: 607 EHGQGPPRKRKRASEPG 623
>gi|20270186 high mobility group nucleosomal binding domain 3
isoform HMGN3a [Homo sapiens]
Length = 99
Score = 47.0 bits (110), Expect = 9e-05
Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
Query: 604 EEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEA 663
+ +SP E ++ + G +V +E ++P PP+P+ K +
Sbjct: 3 KRKSP-ENTEGKDGSKVTKQEPTRRSARLSAKPAPPKPEPKPRKTSAKKEPGAKISRGAK 61
Query: 664 QKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIG 700
K EK EAG EG AP+ GE K + A+K V+ G
Sbjct: 62 GKKEEKQEAGKEGTAPSENGETKAEEAQKTESVDNEG 98
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 46.6 bits (109), Expect = 1e-04
Identities = 34/134 (25%), Positives = 47/134 (35%), Gaps = 9/134 (6%)
Query: 566 DSAEEESTLTKLGNTISSLFGGGTTPDA------KENGTDTVQEEEESPAEGSKDEPGEQ 619
D +S G + G P ENG + E P EG+ P E
Sbjct: 462 DEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSET 521
Query: 620 VELKEEAEA---PVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEG 676
A P E S+ P P P G A E ++ + G + E AE+ E
Sbjct: 522 PGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSET 581
Query: 677 VAPAPEGEKKQKPA 690
P+P G + +PA
Sbjct: 582 PGPSPAGPTRDEPA 595
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 1/92 (1%)
Query: 606 ESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQK 665
+ PAE + PG E P E S+ P P P G A E ++ + G +
Sbjct: 572 DEPAESPSETPGPSPAGPTRDE-PAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPA 630
Query: 666 PSEKAEAGPEGVAPAPEGEKKQKPARKRRMVE 697
E AE+ E P+P G + +PA+ E
Sbjct: 631 GDEPAESPSETPGPSPAGPTRDEPAKAGEAAE 662
Score = 39.7 bits (91), Expect = 0.014
Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 1/85 (1%)
Query: 606 ESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQK 665
+ PAE + PG + + P E S+ P P P G A E ++ + G
Sbjct: 532 DEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 590
Query: 666 PSEKAEAGPEGVAPAPEGEKKQKPA 690
E AE+ E P P G +PA
Sbjct: 591 RDEPAESPSETPGPRPAGPAGDEPA 615
Score = 33.5 bits (75), Expect = 1.0
Identities = 22/86 (25%), Positives = 32/86 (37%), Gaps = 1/86 (1%)
Query: 606 ESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQK 665
+ PAE + PG + + P E S+ P P P G A E ++ + G
Sbjct: 592 DEPAESPSETPGPR-PAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPT 650
Query: 666 PSEKAEAGPEGVAPAPEGEKKQKPAR 691
E A+AG E E K +
Sbjct: 651 RDEPAKAGEAAELQDAEVESSAKSGK 676
>gi|58082089 hypothetical protein LOC161394 [Homo sapiens]
Length = 674
Score = 46.6 bits (109), Expect = 1e-04
Identities = 49/213 (23%), Positives = 83/213 (38%), Gaps = 8/213 (3%)
Query: 556 VESVFETLVEDSAEEESTLTKLGNTISS----LFGGGTTPDAKENGTDTVQEEE--ESPA 609
+ES ET + E+ G T+ L T P E EE E P
Sbjct: 151 LESAMETDPDPVPPTETMSEVSGATVRERNLELLEEETEPGVPEESLRVQHEETGLEPPE 210
Query: 610 EGSKDEPGEQV-ELKEEAEAPVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSE 668
+ +D P E++ E EE + ++P PE + E +K TE + E +
Sbjct: 211 QTKQDFPSEKLGESLEETDLQPPKMTKPETPEETQRESTE-KKRTEPPEQARLEFLEKEP 269
Query: 669 KAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPDLPEDKLAQSVQKLQDLTL 728
+ + G+ P E + + +R+ EE G EL PD P+ K +S + L
Sbjct: 270 RKSSEEAGLEPPEETQPEVPEEMQRKATEEKGTELPERTKPDFPDHKPRKSTDENVPEPL 329
Query: 729 RDLEKQEREKAANSLEAFIFETQDKLYQPEYQE 761
+++ + E+ + Q ++ +PE E
Sbjct: 330 EEIKLEFPEEESRKTNEETILEQSEMMKPESPE 362
Score = 33.1 bits (74), Expect = 1.3
Identities = 54/226 (23%), Positives = 84/226 (37%), Gaps = 28/226 (12%)
Query: 591 PDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGE 650
PD K + E P E K E E+ K E +E P P+ E
Sbjct: 313 PDHKPR--KSTDENVPEPLEEIKLEFPEEESRKTNEETILEQSEMMKPESPE-----EIR 365
Query: 651 KATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARK------RRMVEEIGVELV 704
K+ EK+N Q P E P+ + P E + + KP K E VE
Sbjct: 366 KSNEKKN-----PQPPEETGPVLPQEINPQVEEKTQTKPTEKILELPDETKPRETHVEFS 420
Query: 705 VLDLPD-------LPEDKLAQSVQKLQDLTLRDLEKQEREKAANSLEA-FIFETQDKLYQ 756
D P+ + D+L K L+L D ++E + E+ T + Q
Sbjct: 421 KEDRPEPIKSKYSVGNDELEHREPKRGKLSLSDKFRKEYYALGSLRESEESIGTHYEFLQ 480
Query: 757 P--EYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKEKLAE 800
P + VS E + S + S ++ ++ V + LKE+++E
Sbjct: 481 PLQKLLNVSEECSYSDPSESQTELSEFVHEKEVVDLSQELKERVSE 526
>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
sapiens]
Length = 729
Score = 46.2 bits (108), Expect = 2e-04
Identities = 44/169 (26%), Positives = 69/169 (40%), Gaps = 42/169 (24%)
Query: 591 PDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGSQPPPPEPKGDATPEGE 650
PD + G+DT + ++ P +D+P + + +E E P E PPP PK
Sbjct: 573 PDFESEGSDTQRRADDFPV---RDDPSD---VTDEDEGPAE-----PPPPPKLPLPAFRL 621
Query: 651 KATEKENGDKSEAQKPSEKAEAGPEGVAPAPEGEKKQKPARKRRMVEEIGVELVVLDLPD 710
K G E P E +E G EG P+ E +KK+K ++
Sbjct: 622 KNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEE----------------- 664
Query: 711 LPEDKLAQSVQKLQDLTLRDLEKQEREK------------AANSLEAFI 747
E+K A+ K + ++ K+ER + AA+ LEAF+
Sbjct: 665 --EEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFL 711
>gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
[Homo sapiens]
Length = 806
Score = 45.8 bits (107), Expect = 2e-04
Identities = 55/193 (28%), Positives = 80/193 (41%), Gaps = 26/193 (13%)
Query: 515 NLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVFETLVEDSAEEESTL 574
N+ +K+ + + KK KG+KA L E +LD E+ +E +
Sbjct: 7 NVKKLKVSELKEELKKRR-LSDKGLKAE--LMERLQAALDDEEAGGRPAMEPG----NGS 59
Query: 575 TKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQVELKEEAEAPVEDGS 634
LG + G G +A G D +EEEE EG G+Q+EL EE A S
Sbjct: 60 LDLGGDSAGRSGAGLEQEAAAGG-DEEEEEEEEEEEGISALDGDQMELGEENGAAGAADS 118
Query: 635 QPPPPEPKGDATPEGEKATEKENGD-----KSEAQKPSEKAEAGPEG----VAPAPEGEK 685
P E E A+E ENGD + E + E+ AG E P P +
Sbjct: 119 GP---------MEEEEAASEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQQPQPPATQ 169
Query: 686 KQKPARKRRMVEE 698
+Q+P ++R +E
Sbjct: 170 QQQPQQQRGAAKE 182
Score = 36.2 bits (82), Expect = 0.16
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 13/144 (9%)
Query: 565 EDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQV---E 621
E+ EEE ++ L L A ++G ++EEE + + + D+ G Q E
Sbjct: 87 EEEEEEEEGISALDGDQMELGEENGAAGAADSGP--MEEEEAASEDENGDDQGFQEGEDE 144
Query: 622 LKEEAEAPVED---GSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVA 678
L +E E ++ G Q P P P+ ++ KE KS P G
Sbjct: 145 LGDEEEGAGDENGHGEQQPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLFAVTVAPPGAR 204
Query: 679 PAP-----EGEKKQKPARKRRMVE 697
+G+ +QK K+R V+
Sbjct: 205 QGQQQAGGDGKTEQKGGDKKRGVK 228
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,567,105
Number of Sequences: 37866
Number of extensions: 1991956
Number of successful extensions: 17502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 235
Number of HSP's successfully gapped in prelim test: 891
Number of HSP's that attempted gapping in prelim test: 10629
Number of HSP's gapped (non-prelim): 5541
length of query: 999
length of database: 18,247,518
effective HSP length: 112
effective length of query: 887
effective length of database: 14,006,526
effective search space: 12423788562
effective search space used: 12423788562
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.